500 results on '"Mizuguchi, Mineyuki"'
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2. Combinatorial screening for therapeutics in ATTRv amyloidosis identifies naphthoquinone analogues as TTR-selective amyloid disruptors
3. Development of Benziodarone Analogues with Enhanced Potency for Selective Binding to Transthyretin in Human Plasma
4. Enzymatic activity of cGAS in the presence of three types of DNAs: Limited cGAS stimulation by single-stranded HIV-1 SL2 DNA
5. Glavonoid, a possible supplement for prevention of ATTR amyloidosis
6. Structural and dynamics analysis of intrinsically disordered proteins by high-speed atomic force microscopy
7. Trypsin‐induced aggregation of transthyretin Valine 30 variants associated with hereditary amyloidosis.
8. Tau activates microglia via the PQBP1-cGAS-STING pathway to promote brain inflammation
9. Resveratrol Derivatives Inhibit Transthyretin Fibrillization: Structural Insights into the Interactions between Resveratrol Derivatives and Transthyretin
10. New cytotoxic polyacetylene alcohols from the Egyptian marine sponge Siphonochalina siphonella
11. Discovery of a new class of MTH1 inhibitor by X-ray crystallographic screening
12. The Accumulation of Heparan Sulfate S-Domains in Kidney Transthyretin Deposits Accelerates Fibril Formation and Promotes Cytotoxicity
13. Characterization of susceptibility variants of poliovirus grown in the presence of favipiravir
14. Rafoxanide, a salicylanilide anthelmintic, interacts with human plasma protein transthyretin
15. Design and Structural Optimization of Thiadiazole Derivatives with Potent GLS1 Inhibitory Activity
16. Design, synthesis, structure–activity relationship studies, and evaluation of novel GLS1 inhibitors
17. DPP8 Selective Inhibitor Tominostat as a Novel and Broad-Spectrum Anticancer Agent against Hematological Malignancies
18. A novel serine racemase inhibitor suppresses neuronal over-activation in vivo
19. Crystallization and Biophysical Approaches for Studying the Interactions Between the Vps4-MIT Domain and ESCRT-III Proteins
20. Chlorinated Naringenin Analogues as Potential Inhibitors of Transthyretin Amyloidogenesis
21. Structural and mutational analyses of decarboxylated osteocalcin provide insight into its adiponectin‐inducing activity.
22. The hydrophobic residue Leu73 is crucial for the high stability and low aggregation properties of murine transthyretin
23. Multifunctional Therapeutic Cyclodextrin-Appended Dendrimer Complex for Treatment of Systemic and Localized Amyloidosis
24. Determination of Hardness of a Pharmaceutical Oral Jelly by Using T2 Relaxation Behavior Measured by Time-Domain NMR
25. Neutron crystallographic analysis of the nucleotide-binding domain of Hsp72 in complex with ADP
26. Interaction between tachyplesin I, an antimicrobial peptide derived from horseshoe crab, and lipopolysaccharide
27. Effect of albumin on transthyretin and amyloidogenic transthyretin Val30Met disposition and tissue deposition in familial amyloidotic polyneuropathy
28. Aged vervet monkeys developing transthyretin amyloidosis with the human disease-causing Ile122 allele: a valid pathological model of the human disease
29. A chalcone derivative suppresses TSLP induction in mice and human keratinocytes through binding to BET family proteins
30. Repositioning of the Anthelmintic Drugs Bithionol and Triclabendazole as Transthyretin Amyloidogenesis Inhibitors
31. Rifampicin is a candidate preventive medicine against amyloid-β and tau oligomers
32. Overexpression of an antimicrobial peptide derived from C. elegans using an aggregation-prone protein coexpression system
33. Phenolic compounds prevent the oligomerization of α-synuclein and reduce synaptic toxicity
34. Polyglutamine tract-binding protein-1 binds to U5-15kD via a continuous 23-residue segment of the C-terminal domain
35. Inhibitory activities of anthraquinone and xanthone derivatives against transthyretin amyloidogenesis
36. Polyglutamine tract binding protein-1 is an intrinsically unstructured protein
37. Chapter 2 NMR Studies of Protein Folding: Folding Studies of Calcium‐Binding Lysozyme and α‐Lactalbumin
38. Crystal structure of death-associated protein kinase 1 in complex with the dietary compound resveratrol
39. Characterization of the denatured structure of pyrrolidone carboxyl peptidase from a hyperthermophile under nondenaturing conditions: Role of the C-terminal [alpha]-helix of the protein in folding and stability
40. Structural approach to a novel tandem repeat DNA-building domain, STPR, by CD and NMR
41. Biosensor recognition of thyroid-disrupting chemicals using transport proteins
42. Disassembling and bleaching of chloride-free pharaonis halorhodopsin by octyl-beta-glucoside
43. Structural and dynamics analysis of intrinsically disordered proteins by high-speed atomic force microscopy
44. Neutron diffraction experiment with the Y116S variant of transthyretin using iBIX at J-PARC: application of a new integration method
45. A low amyloidogenic E61K transthyretin mutation may cause familial amyloid polyneuropathy
46. Transthyretin Amyloidogenesis Inhibitors: From Discovery to Current Developments
47. Stabilization of protein by replacement of a fluctuating loop: structural analysis of a chimera of bovine alpha-lactalbumin and equine lysozyme
48. Expression of SOLOIST/MRTFB i4, a novel neuronal isoform of the mouse serum response factor coactivator myocardin‐related transcription factor‐B, negatively regulates dendritic complexity in cortical neurons
49. Structural and thermodynamic analyses of interactions between death-associated protein kinase 1 and anthraquinones
50. New cytotoxic polyacetylene amides from the Egyptian marine sponge Siphonochalina siphonella
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