605 results on '"Moccia, M."'
Search Results
2. The role of biomarkers in differential diagnosis of neurodegenerative dementias: A case report
- Author
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Carbone, G., primary, La Civita, E., additional, Fiorenza, M., additional, Nicolella, V., additional, Jannuzzi, G., additional, Sirica, R., additional, Felicelli, G., additional, Delle Cave, T., additional, Sansone, R., additional, D’Angelo, M., additional, Moccia, M., additional, Brescia Morra, V., additional, and Terracciano, D., additional
- Published
- 2024
- Full Text
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3. Clinical validation in multiple sclerosis of the lumipulse immunoassay for plasma neurofilament light chain
- Author
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Fiorenza, M., primary, Carbone, G., additional, La Civita, E., additional, Felicelli, G., additional, Sansone, R., additional, Delle Cave, T., additional, D’Angelo, M., additional, Sirica, R., additional, Jannuzzi, G., additional, Nicolella, V., additional, Moccia, M., additional, Brescia Morra, V., additional, and Terracciano, D., additional
- Published
- 2024
- Full Text
- View/download PDF
4. Global investments in pandemic preparedness and COVID-19: development assistance and domestic spending on health between 1990 and 2026
- Author
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Micah, A, Bhangdia, K, Cogswell, I, Lasher, D, Lidral-Porter, B, Maddison, E, Nguyen, T, Patel, N, Pedroza, P, Solorio, J, Stutzman, H, Tsakalos, G, Wang, Y, Warriner, W, Zhao, Y, Zlavog, B, Abbafati, C, Abbas, J, Abbasi-Kangevari, M, Abbasi-Kangevari, Z, Abdelmasseh, M, Abdulah, D, Abedi, A, Abegaz, K, Abhilash, E, Aboagye, R, Abolhassani, H, Abrigo, M, Abubaker Ali, H, Abu-Gharbieh, E, Adem, M, Afzal, M, Ahmadi, A, Ahmed, H, Ahmed Rashid, T, Aji, B, Akbarialiabad, H, Akelew, Y, Al Hamad, H, Alam, K, Alanezi, F, Alanzi, T, Al-Hanawi, M, Alhassan, R, Aljunid, S, Almustanyir, S, Al-Raddadi, R, Alvis-Guzman, N, Alvis-Zakzuk, N, Amare, A, Ameyaw, E, Amini-Rarani, M, Amu, H, Ancuceanu, R, Andrei, T, Anwar, S, Appiah, F, Aqeel, M, Arabloo, J, Arab-Zozani, M, Aravkin, A, Aremu, O, Aruleba, R, Athari, S, Avila-Burgos, L, Ayanore, M, Azari, S, Baig, A, Bantie, A, Barrow, A, Baskaran, P, Basu, S, Batiha, A, Baune, B, Berezvai, Z, Bhardwaj, N, Bhardwaj, P, Bhaskar, S, Boachie, M, Bodolica, V, Botelho, J, Braithwaite, D, Breitborde, N, Busse, R, Cahuana-Hurtado, L, Catala-Lopez, F, Chansa, C, Charan, J, Chattu, V, Chen, S, Chukwu, I, Dadras, O, Dandona, L, Dandona, R, Dargahi, A, Debela, S, Denova-Gutierrez, E, Desye, B, Dharmaratne, S, Diao, N, Doan, L, Dodangeh, M, dos Santos, W, Doshmangir, L, Dube, J, Eini, E, El Sayed Zaki, M, El Tantawi, M, Enyew, D, Eskandarieh, S, Ezati Asar, M, Fagbamigbe, A, Faraon, E, Fatehizadeh, A, Fattahi, H, Fekadu, G, Fischer, F, Foigt, N, Fowobaje, K, Freitas, A, Fukumoto, T, Fullman, N, Gaal, P, Gamkrelidze, A, Garcia-Gordillo, M, Gebrehiwot, M, Gerema, U, Ghafourifard, M, Ghamari, S, Ghanbari, R, Ghashghaee, A, Gholamrezanezhad, A, Golechha, M, Golinelli, D, Goshu, Y, Goyomsa, G, Guha, A, Gunawardane, D, Gupta, B, Hamidi, S, Harapan, H, Hashempour, R, Hayat, K, Heidari, G, Heredia-Pi, I, Herteliu, C, Heyi, D, Hezam, K, Hiraike, Y, Hlongwa, M, Holla, R, Hoque, M, Hosseinzadeh, M, Hostiuc, S, Hussain, S, Ilesanmi, O, Immurana, M, Iradukunda, A, Ismail, N, Isola, G, J, L, Jakovljevic, M, Jalili, M, Janodia, M, Javaheri, T, Jayapal, S, Jemere, D, Joo, T, Joseph, N, Jozwiak, J, Jurisson, M, Kaambwa, B, Kadashetti, V, Kadel, R, Kadir, D, Kalankesh, L, Kamath, R, Kandel, H, Kantar, R, Karanth, S, Karaye, I, Karimi, S, Kassa, B, Kayode, G, Keikavoosi-Arani, L, Keshri, V, Keskin, C, Khader, Y, Khafaie, M, Khajuria, H, Khayat Kashani, H, Kifle, Z, Kim, H, Kim, J, Kim, M, Kim, Y, Kisa, A, Kohler, S, Kompani, F, Kosen, S, Koulmane Laxminarayana, S, Koyanagi, A, Krishan, K, Kusuma, D, Lam, J, Lamnisos, D, Larsson, A, Lee, S, Lee, W, Lee, Y, Lenzi, J, Lim, L, Lorenzovici, L, Lozano, R, Machado, V, Madadizadeh, F, Magdy Abd El Razek, M, Mahmoudi, R, Majeed, A, Malekpour, M, Manda, A, Mansouri, B, Mansournia, M, Mantovani, L, Marrugo Arnedo, C, Martorell, M, Masoud, A, Mathews, E, Maude, R, Mechili, E, Mehrabi Nasab, E, Mendes, J, Meretoja, A, Meretoja, T, Mesregah, M, Mestrovic, T, Mirica, A, Mirrakhimov, E, Mirutse, M, Mirza, M, Mirza-Aghazadeh-Attari, M, Misganaw, A, Moccia, M, Moghadasi, J, Mohammadi, E, Mohammadi, M, Mohammadian-Hafshejani, A, Mohammadshahi, M, Mohammed, S, Mohseni, M, Mokdad, A, Monasta, L, Mossialos, E, Mostafavi, E, Mousavi Isfahani, H, Mpundu-Kaambwa, C, Murthy, S, Muthupandian, S, Nagarajan, A, Naidoo, K, Naimzada, M, Nangia, V, Naqvi, A, Nayak, B, Ndejjo, R, Noroozi, N, Noubiap, J, Nuruzzaman, K, Nzoputam, C, Nzoputam, O, Oancea, B, Obi, F, Ogunkoya, A, Oh, I, Okonji, O, Olagunju, A, Olagunju, T, Olakunde, B, Omar Bali, A, Onwujekwe, O, Opio, J, Otoiu, A, Otstavnov, N, Otstavnov, S, Owolabi, M, Palicz, T, Palladino, R, Pana, A, Parekh, T, Pasupula, D, Patel, J, Patton, G, Paudel, U, Paun, M, Pawar, S, Perna, S, Perumalsamy, N, Petcu, I, Piracha, Z, Poursadeqiyan, M, Pourtaheri, N, Prada, S, Rafiei, S, Raghav, P, Rahim, F, Rahman, M, Rahmani, A, Ranabhat, C, Raru, T, Rashedi, S, Rashidi, M, Ravangard, R, Rawaf, S, Rawassizadeh, R, Redwan, E, Reiner, R, Renzaho, A, Rezaei, M, Rezaei, N, Riaz, M, Rodriguez, J, Saad, A, Saddik, B, Sadeghian, S, Saeb, M, Saeed, U, Sahu, M, Saki, M, Salamati, P, Salari, H, Salehi, S, Samy, A, Sanabria, J, Sanmarchi, F, Santos, J, Santric-Milicevic, M, Sao Jose, B, Sarikhani, Y, Sathian, B, Satpathy, M, Savic, M, Sayadi, Y, Schwendicke, F, Senthilkumaran, S, Sepanlou, S, Servan-Mori, E, Setshegetso, N, Seylani, A, Shahabi, S, Shaikh, M, Shakhmardanov, M, Shanawaz, M, Sharew, M, Sharew, N, Sharma, R, Shayan, M, Sheikh, A, Shenoy, S, Shetty, A, Shetty, P, Shivakumar, K, Silva, L, Simegn, W, Singh, J, Singh, K, Skhvitaridze, N, Skryabin, V, Skryabina, A, Socea, B, Solomon, Y, Song, S, Stefan, S, Suleman, M, Tabares-Seisdedos, R, Tat, N, Tat, V, Tefera, B, Tichopad, A, Tobe-Gai, R, Tovani-Palone, M, Tudor Car, L, Tufa, D, Vasankari, T, Vasic, M, Vervoort, D, Vlassov, V, Vo, B, Vu, L, Waheed, Y, Wamai, R, Wang, C, Wassie, G, Wickramasinghe, N, Yaya, S, Yigit, A, Yigit, V, Yonemoto, N, Younis, M, Yu, C, Yunusa, I, Zaki, L, Zaman, B, Zangeneh, A, Zare Dehnavi, A, Zastrozhin, M, Zeng, W, Zhang, Z, Zuhlke, L, Zuniga, Y, Hay, S, Murray, C, Dieleman, J, Micah A. E., Bhangdia K., Cogswell I. E., Lasher D., Lidral-Porter B., Maddison E. R., Nguyen T. N. N., Patel N., Pedroza P., Solorio J., Stutzman H., Tsakalos G., Wang Y., Warriner W., Zhao Y., Zlavog B. S., Abbafati C., Abbas J., Abbasi-Kangevari M., Abbasi-Kangevari Z., Abdelmasseh M., Abdulah D. M., Abedi A., Abegaz K. H., Abhilash E. S., Aboagye R. G., Abolhassani H., Abrigo M. R. M., Abubaker Ali H., Abu-Gharbieh E., Adem M. H., Afzal M. S., Ahmadi A., Ahmed H., Ahmed Rashid T., Aji B., Akbarialiabad H., Akelew Y., Al Hamad H., Alam K., Alanezi F. M., Alanzi T. M., Al-Hanawi M. K., Alhassan R. K., Aljunid S. M., Almustanyir S., Al-Raddadi R. M., Alvis-Guzman N., Alvis-Zakzuk N. J., Amare A. T., Ameyaw E. K., Amini-Rarani M., Amu H., Ancuceanu R., Andrei T., Anwar S. L., Appiah F., Aqeel M., Arabloo J., Arab-Zozani M., Aravkin A. Y., Aremu O., Aruleba R. T., Athari S. S., Avila-Burgos L., Ayanore M. A., Azari S., Baig A. A., Bantie A. T., Barrow A., Baskaran P., Basu S., Batiha A. -M. M., Baune B. T., Berezvai Z., Bhardwaj N., Bhardwaj P., Bhaskar S., Boachie M. K., Bodolica V., Botelho J. S. B., Braithwaite D., Breitborde N. J. K., Busse R., Cahuana-Hurtado L., Catala-Lopez F., Chansa C., Charan J., Chattu V. K., Chen S., Chukwu I. S., Dadras O., Dandona L., Dandona R., Dargahi A., Debela S. A., Denova-Gutierrez E., Desye B., Dharmaratne S. D., Diao N., Doan L. P., Dodangeh M., dos Santos W. M., Doshmangir L., Dube J., Eini E., El Sayed Zaki M., El Tantawi M., Enyew D. B., Eskandarieh S., Ezati Asar M., Fagbamigbe A. F., Faraon E. J. A., Fatehizadeh A., Fattahi H., Fekadu G., Fischer F., Foigt N. A., Fowobaje K. R., Freitas A., Fukumoto T., Fullman N., Gaal P. A., Gamkrelidze A., Garcia-Gordillo M. A., Gebrehiwot M., Gerema U., Ghafourifard M., Ghamari S. -H., Ghanbari R., Ghashghaee A., Gholamrezanezhad A., Golechha M., Golinelli D., Goshu Y. A., Goyomsa G. G., Guha A., Gunawardane D. A., Gupta B., Hamidi S., Harapan H., Hashempour R., Hayat K., Heidari G., Heredia-Pi I., Herteliu C., Heyi D. Z., Hezam K., Hiraike Y., Hlongwa M. M., Holla R., Hoque M. E., Hosseinzadeh M., Hostiuc S., Hussain S., Ilesanmi O. S., Immurana M., Iradukunda A., Ismail N. E., Isola G., J L. M., Jakovljevic M., Jalili M., Janodia M. D., Javaheri T., Jayapal S. K., Jemere D. M., Joo T., Joseph N., Jozwiak J. J., Jurisson M., Kaambwa B., Kadashetti V., Kadel R., Kadir D. H., Kalankesh L. R., Kamath R., Kandel H., Kantar R. S., Karanth S. D., Karaye I. M., Karimi S. E., Kassa B. G., Kayode G. A., Keikavoosi-Arani L., Keshri V. R., Keskin C., Khader Y. S., Khafaie M. A., Khajuria H., Khayat Kashani H. R., Kifle Z. D., Kim H., Kim J., Kim M. S., Kim Y. J., Kisa A., Kohler S., Kompani F., Kosen S., Koulmane Laxminarayana S. L., Koyanagi A., Krishan K., Kusuma D., Lam J., Lamnisos D., Larsson A. O., Lee S. -W., Lee S. W. H., Lee W. -C., Lee Y. H., Lenzi J., Lim L. -L., Lorenzovici L., Lozano R., Machado V. S. M., Madadizadeh F., Magdy Abd El Razek M., Mahmoudi R., Majeed A., Malekpour M. -R., Manda A. L., Mansouri B., Mansournia M. A., Mantovani L. G., Marrugo Arnedo C. A., Martorell M., Masoud A., Mathews E., Maude R. J., Mechili E. A., Mehrabi Nasab E., Mendes J. J. J. M., Meretoja A., Meretoja T. J., Mesregah M. K., Mestrovic T., Mirica A., Mirrakhimov E. M., Mirutse M. K., Mirza M., Mirza-Aghazadeh-Attari M., Misganaw A., Moccia M., Moghadasi J., Mohammadi E., Mohammadi M., Mohammadian-Hafshejani A., Mohammadshahi M., Mohammed S., Mohseni M., Mokdad A. H., Monasta L., Mossialos E., Mostafavi E., Mousavi Isfahani H., Mpundu-Kaambwa C., Murthy S., Muthupandian S., Nagarajan A. J., Naidoo K. S., Naimzada M. D., Nangia V., Naqvi A. A., Nayak B. P., Ndejjo R., Nguyen T. H., Noroozi N., Noubiap J. J., Nuruzzaman K. M., Nzoputam C. I., Nzoputam O. J., Oancea B., Obi F. C. A., Ogunkoya A., Oh I. -H., Okonji O. C., Olagunju A. T., Olagunju T. O., Olakunde B. O., Omar Bali A., Onwujekwe O. E., Opio J. N., Otoiu A., Otstavnov N., Otstavnov S. S., Owolabi M. O., Palicz T., Palladino R., Pana A., Parekh T., Pasupula D. K., Patel J., Patton G. C., Paudel U., Paun M., Pawar S., Perna S., Perumalsamy N., Petcu I. -R., Piracha Z. Z., Poursadeqiyan M., Pourtaheri N., Prada S. I., Rafiei S., Raghav P. R., Rahim F., Rahman M. H. U., Rahman M., Rahmani A. M., Ranabhat C. L., Raru T. B., Rashedi S., Rashidi M. -M., Ravangard R., Rawaf S., Rawassizadeh R., Redwan E. M. M., Reiner R. C., Renzaho A. M. N., Rezaei M., Rezaei N., Riaz M. A., Rodriguez J. A. B., Saad A. M. A., Saddik B., Sadeghian S., Saeb M. R., Saeed U., Sahu M., Saki M., Salamati P., Salari H., Salehi S., Samy A. M., Sanabria J., Sanmarchi F., Santos J. V., Santric-Milicevic M. M., Sao Jose B. P., Sarikhani Y., Sathian B., Satpathy M., Savic M., Sayadi Y., Schwendicke F., Senthilkumaran S., Sepanlou S. G., Servan-Mori E., Setshegetso N., Seylani A., Shahabi S., Shaikh M. A., Shakhmardanov M. Z., Shanawaz M., Sharew M. M. S., Sharew N. T., Sharma R., Shayan M., Sheikh A., Shenoy S. M., Shetty A., Shetty P. H., Shivakumar K. M., Silva L. M. L. R., Simegn W., Singh J. A., Singh K., Skhvitaridze N., Skryabin V. Y., Skryabina A. A., Socea B., Solomon Y., Song S., Stefan S. C., Suleman M., Tabares-Seisdedos R., Tat N. Y., Tat V. Y., Tefera B. N., Tichopad A., Tobe-Gai R., Tovani-Palone M. R., Tudor Car L., Tufa D. G., Vasankari T. J., Vasic M., Vervoort D., Vlassov V., Vo B., Vu L. G., Waheed Y., Wamai R. G., Wang C., Wassie G. T., Wickramasinghe N. D., Yaya S., Yigit A., Yigit V., Yonemoto N., Younis M. Z., Yu C., Yunusa I., Zaki L., Zaman B. A., Zangeneh A., Zare Dehnavi A., Zastrozhin M. S., Zeng W., Zhang Z. -J., Zuhlke L. J., Zuniga Y. M. H., Hay S. I., Murray C. J. L., Dieleman J. L., Micah, A, Bhangdia, K, Cogswell, I, Lasher, D, Lidral-Porter, B, Maddison, E, Nguyen, T, Patel, N, Pedroza, P, Solorio, J, Stutzman, H, Tsakalos, G, Wang, Y, Warriner, W, Zhao, Y, Zlavog, B, Abbafati, C, Abbas, J, Abbasi-Kangevari, M, Abbasi-Kangevari, Z, Abdelmasseh, M, Abdulah, D, Abedi, A, Abegaz, K, Abhilash, E, Aboagye, R, Abolhassani, H, Abrigo, M, Abubaker Ali, H, Abu-Gharbieh, E, Adem, M, Afzal, M, Ahmadi, A, Ahmed, H, Ahmed Rashid, T, Aji, B, Akbarialiabad, H, Akelew, Y, Al Hamad, H, Alam, K, Alanezi, F, Alanzi, T, Al-Hanawi, M, Alhassan, R, Aljunid, S, Almustanyir, S, Al-Raddadi, R, Alvis-Guzman, N, Alvis-Zakzuk, N, Amare, A, Ameyaw, E, Amini-Rarani, M, Amu, H, Ancuceanu, R, Andrei, T, Anwar, S, Appiah, F, Aqeel, M, Arabloo, J, Arab-Zozani, M, Aravkin, A, Aremu, O, Aruleba, R, Athari, S, Avila-Burgos, L, Ayanore, M, Azari, S, Baig, A, Bantie, A, Barrow, A, Baskaran, P, Basu, S, Batiha, A, Baune, B, Berezvai, Z, Bhardwaj, N, Bhardwaj, P, Bhaskar, S, Boachie, M, Bodolica, V, Botelho, J, Braithwaite, D, Breitborde, N, Busse, R, Cahuana-Hurtado, L, Catala-Lopez, F, Chansa, C, Charan, J, Chattu, V, Chen, S, Chukwu, I, Dadras, O, Dandona, L, Dandona, R, Dargahi, A, Debela, S, Denova-Gutierrez, E, Desye, B, Dharmaratne, S, Diao, N, Doan, L, Dodangeh, M, dos Santos, W, Doshmangir, L, Dube, J, Eini, E, El Sayed Zaki, M, El Tantawi, M, Enyew, D, Eskandarieh, S, Ezati Asar, M, Fagbamigbe, A, Faraon, E, Fatehizadeh, A, Fattahi, H, Fekadu, G, Fischer, F, Foigt, N, Fowobaje, K, Freitas, A, Fukumoto, T, Fullman, N, Gaal, P, Gamkrelidze, A, Garcia-Gordillo, M, Gebrehiwot, M, Gerema, U, Ghafourifard, M, Ghamari, S, Ghanbari, R, Ghashghaee, A, Gholamrezanezhad, A, Golechha, M, Golinelli, D, Goshu, Y, Goyomsa, G, Guha, A, Gunawardane, D, Gupta, B, Hamidi, S, Harapan, H, Hashempour, R, Hayat, K, Heidari, G, Heredia-Pi, I, Herteliu, C, Heyi, D, Hezam, K, Hiraike, Y, Hlongwa, M, Holla, R, Hoque, M, Hosseinzadeh, M, Hostiuc, S, Hussain, S, Ilesanmi, O, Immurana, M, Iradukunda, A, Ismail, N, Isola, G, J, L, Jakovljevic, M, Jalili, M, Janodia, M, Javaheri, T, Jayapal, S, Jemere, D, Joo, T, Joseph, N, Jozwiak, J, Jurisson, M, Kaambwa, B, Kadashetti, V, Kadel, R, Kadir, D, Kalankesh, L, Kamath, R, Kandel, H, Kantar, R, Karanth, S, Karaye, I, Karimi, S, Kassa, B, Kayode, G, Keikavoosi-Arani, L, Keshri, V, Keskin, C, Khader, Y, Khafaie, M, Khajuria, H, Khayat Kashani, H, Kifle, Z, Kim, H, Kim, J, Kim, M, Kim, Y, Kisa, A, Kohler, S, Kompani, F, Kosen, S, Koulmane Laxminarayana, S, Koyanagi, A, Krishan, K, Kusuma, D, Lam, J, Lamnisos, D, Larsson, A, Lee, S, Lee, W, Lee, Y, Lenzi, J, Lim, L, Lorenzovici, L, Lozano, R, Machado, V, Madadizadeh, F, Magdy Abd El Razek, M, Mahmoudi, R, Majeed, A, Malekpour, M, Manda, A, Mansouri, B, Mansournia, M, Mantovani, L, Marrugo Arnedo, C, Martorell, M, Masoud, A, Mathews, E, Maude, R, Mechili, E, Mehrabi Nasab, E, Mendes, J, Meretoja, A, Meretoja, T, Mesregah, M, Mestrovic, T, Mirica, A, Mirrakhimov, E, Mirutse, M, Mirza, M, Mirza-Aghazadeh-Attari, M, Misganaw, A, Moccia, M, Moghadasi, J, Mohammadi, E, Mohammadi, M, Mohammadian-Hafshejani, A, Mohammadshahi, M, Mohammed, S, Mohseni, M, Mokdad, A, Monasta, L, Mossialos, E, Mostafavi, E, Mousavi Isfahani, H, Mpundu-Kaambwa, C, Murthy, S, Muthupandian, S, Nagarajan, A, Naidoo, K, Naimzada, M, Nangia, V, Naqvi, A, Nayak, B, Ndejjo, R, Noroozi, N, Noubiap, J, Nuruzzaman, K, Nzoputam, C, Nzoputam, O, Oancea, B, Obi, F, Ogunkoya, A, Oh, I, Okonji, O, Olagunju, A, Olagunju, T, Olakunde, B, Omar Bali, A, Onwujekwe, O, Opio, J, Otoiu, A, Otstavnov, N, Otstavnov, S, Owolabi, M, Palicz, T, Palladino, R, Pana, A, Parekh, T, Pasupula, D, Patel, J, Patton, G, Paudel, U, Paun, M, Pawar, S, Perna, S, Perumalsamy, N, Petcu, I, Piracha, Z, Poursadeqiyan, M, Pourtaheri, N, Prada, S, Rafiei, S, Raghav, P, Rahim, F, Rahman, M, Rahmani, A, Ranabhat, C, Raru, T, Rashedi, S, Rashidi, M, Ravangard, R, Rawaf, S, Rawassizadeh, R, Redwan, E, Reiner, R, Renzaho, A, Rezaei, M, Rezaei, N, Riaz, M, Rodriguez, J, Saad, A, Saddik, B, Sadeghian, S, Saeb, M, Saeed, U, Sahu, M, Saki, M, Salamati, P, Salari, H, Salehi, S, Samy, A, Sanabria, J, Sanmarchi, F, Santos, J, Santric-Milicevic, M, Sao Jose, B, Sarikhani, Y, Sathian, B, Satpathy, M, Savic, M, Sayadi, Y, Schwendicke, F, Senthilkumaran, S, Sepanlou, S, Servan-Mori, E, Setshegetso, N, Seylani, A, Shahabi, S, Shaikh, M, Shakhmardanov, M, Shanawaz, M, Sharew, M, Sharew, N, Sharma, R, Shayan, M, Sheikh, A, Shenoy, S, Shetty, A, Shetty, P, Shivakumar, K, Silva, L, Simegn, W, Singh, J, Singh, K, Skhvitaridze, N, Skryabin, V, Skryabina, A, Socea, B, Solomon, Y, Song, S, Stefan, S, Suleman, M, Tabares-Seisdedos, R, Tat, N, Tat, V, Tefera, B, Tichopad, A, Tobe-Gai, R, Tovani-Palone, M, Tudor Car, L, Tufa, D, Vasankari, T, Vasic, M, Vervoort, D, Vlassov, V, Vo, B, Vu, L, Waheed, Y, Wamai, R, Wang, C, Wassie, G, Wickramasinghe, N, Yaya, S, Yigit, A, Yigit, V, Yonemoto, N, Younis, M, Yu, C, Yunusa, I, Zaki, L, Zaman, B, Zangeneh, A, Zare Dehnavi, A, Zastrozhin, M, Zeng, W, Zhang, Z, Zuhlke, L, Zuniga, Y, Hay, S, Murray, C, Dieleman, J, Micah A. E., Bhangdia K., Cogswell I. E., Lasher D., Lidral-Porter B., Maddison E. R., Nguyen T. N. N., Patel N., Pedroza P., Solorio J., Stutzman H., Tsakalos G., Wang Y., Warriner W., Zhao Y., Zlavog B. S., Abbafati C., Abbas J., Abbasi-Kangevari M., Abbasi-Kangevari Z., Abdelmasseh M., Abdulah D. M., Abedi A., Abegaz K. H., Abhilash E. S., Aboagye R. G., Abolhassani H., Abrigo M. R. M., Abubaker Ali H., Abu-Gharbieh E., Adem M. H., Afzal M. S., Ahmadi A., Ahmed H., Ahmed Rashid T., Aji B., Akbarialiabad H., Akelew Y., Al Hamad H., Alam K., Alanezi F. M., Alanzi T. M., Al-Hanawi M. K., Alhassan R. K., Aljunid S. M., Almustanyir S., Al-Raddadi R. M., Alvis-Guzman N., Alvis-Zakzuk N. J., Amare A. T., Ameyaw E. K., Amini-Rarani M., Amu H., Ancuceanu R., Andrei T., Anwar S. L., Appiah F., Aqeel M., Arabloo J., Arab-Zozani M., Aravkin A. Y., Aremu O., Aruleba R. T., Athari S. S., Avila-Burgos L., Ayanore M. A., Azari S., Baig A. A., Bantie A. T., Barrow A., Baskaran P., Basu S., Batiha A. -M. M., Baune B. T., Berezvai Z., Bhardwaj N., Bhardwaj P., Bhaskar S., Boachie M. K., Bodolica V., Botelho J. S. B., Braithwaite D., Breitborde N. J. K., Busse R., Cahuana-Hurtado L., Catala-Lopez F., Chansa C., Charan J., Chattu V. K., Chen S., Chukwu I. S., Dadras O., Dandona L., Dandona R., Dargahi A., Debela S. A., Denova-Gutierrez E., Desye B., Dharmaratne S. D., Diao N., Doan L. P., Dodangeh M., dos Santos W. M., Doshmangir L., Dube J., Eini E., El Sayed Zaki M., El Tantawi M., Enyew D. B., Eskandarieh S., Ezati Asar M., Fagbamigbe A. F., Faraon E. J. A., Fatehizadeh A., Fattahi H., Fekadu G., Fischer F., Foigt N. A., Fowobaje K. R., Freitas A., Fukumoto T., Fullman N., Gaal P. A., Gamkrelidze A., Garcia-Gordillo M. A., Gebrehiwot M., Gerema U., Ghafourifard M., Ghamari S. -H., Ghanbari R., Ghashghaee A., Gholamrezanezhad A., Golechha M., Golinelli D., Goshu Y. A., Goyomsa G. G., Guha A., Gunawardane D. A., Gupta B., Hamidi S., Harapan H., Hashempour R., Hayat K., Heidari G., Heredia-Pi I., Herteliu C., Heyi D. Z., Hezam K., Hiraike Y., Hlongwa M. M., Holla R., Hoque M. E., Hosseinzadeh M., Hostiuc S., Hussain S., Ilesanmi O. S., Immurana M., Iradukunda A., Ismail N. E., Isola G., J L. M., Jakovljevic M., Jalili M., Janodia M. D., Javaheri T., Jayapal S. K., Jemere D. M., Joo T., Joseph N., Jozwiak J. J., Jurisson M., Kaambwa B., Kadashetti V., Kadel R., Kadir D. H., Kalankesh L. R., Kamath R., Kandel H., Kantar R. S., Karanth S. D., Karaye I. M., Karimi S. E., Kassa B. G., Kayode G. A., Keikavoosi-Arani L., Keshri V. R., Keskin C., Khader Y. S., Khafaie M. A., Khajuria H., Khayat Kashani H. R., Kifle Z. D., Kim H., Kim J., Kim M. S., Kim Y. J., Kisa A., Kohler S., Kompani F., Kosen S., Koulmane Laxminarayana S. L., Koyanagi A., Krishan K., Kusuma D., Lam J., Lamnisos D., Larsson A. O., Lee S. -W., Lee S. W. H., Lee W. -C., Lee Y. H., Lenzi J., Lim L. -L., Lorenzovici L., Lozano R., Machado V. S. M., Madadizadeh F., Magdy Abd El Razek M., Mahmoudi R., Majeed A., Malekpour M. -R., Manda A. L., Mansouri B., Mansournia M. A., Mantovani L. G., Marrugo Arnedo C. A., Martorell M., Masoud A., Mathews E., Maude R. J., Mechili E. A., Mehrabi Nasab E., Mendes J. J. J. M., Meretoja A., Meretoja T. J., Mesregah M. K., Mestrovic T., Mirica A., Mirrakhimov E. M., Mirutse M. K., Mirza M., Mirza-Aghazadeh-Attari M., Misganaw A., Moccia M., Moghadasi J., Mohammadi E., Mohammadi M., Mohammadian-Hafshejani A., Mohammadshahi M., Mohammed S., Mohseni M., Mokdad A. H., Monasta L., Mossialos E., Mostafavi E., Mousavi Isfahani H., Mpundu-Kaambwa C., Murthy S., Muthupandian S., Nagarajan A. J., Naidoo K. S., Naimzada M. D., Nangia V., Naqvi A. A., Nayak B. P., Ndejjo R., Nguyen T. H., Noroozi N., Noubiap J. J., Nuruzzaman K. M., Nzoputam C. I., Nzoputam O. J., Oancea B., Obi F. C. A., Ogunkoya A., Oh I. -H., Okonji O. C., Olagunju A. T., Olagunju T. O., Olakunde B. O., Omar Bali A., Onwujekwe O. E., Opio J. N., Otoiu A., Otstavnov N., Otstavnov S. S., Owolabi M. O., Palicz T., Palladino R., Pana A., Parekh T., Pasupula D. K., Patel J., Patton G. C., Paudel U., Paun M., Pawar S., Perna S., Perumalsamy N., Petcu I. -R., Piracha Z. Z., Poursadeqiyan M., Pourtaheri N., Prada S. I., Rafiei S., Raghav P. R., Rahim F., Rahman M. H. U., Rahman M., Rahmani A. M., Ranabhat C. L., Raru T. B., Rashedi S., Rashidi M. -M., Ravangard R., Rawaf S., Rawassizadeh R., Redwan E. M. M., Reiner R. C., Renzaho A. M. N., Rezaei M., Rezaei N., Riaz M. A., Rodriguez J. A. B., Saad A. M. A., Saddik B., Sadeghian S., Saeb M. R., Saeed U., Sahu M., Saki M., Salamati P., Salari H., Salehi S., Samy A. M., Sanabria J., Sanmarchi F., Santos J. V., Santric-Milicevic M. M., Sao Jose B. P., Sarikhani Y., Sathian B., Satpathy M., Savic M., Sayadi Y., Schwendicke F., Senthilkumaran S., Sepanlou S. G., Servan-Mori E., Setshegetso N., Seylani A., Shahabi S., Shaikh M. A., Shakhmardanov M. Z., Shanawaz M., Sharew M. M. S., Sharew N. T., Sharma R., Shayan M., Sheikh A., Shenoy S. M., Shetty A., Shetty P. H., Shivakumar K. M., Silva L. M. L. R., Simegn W., Singh J. A., Singh K., Skhvitaridze N., Skryabin V. Y., Skryabina A. A., Socea B., Solomon Y., Song S., Stefan S. C., Suleman M., Tabares-Seisdedos R., Tat N. Y., Tat V. Y., Tefera B. N., Tichopad A., Tobe-Gai R., Tovani-Palone M. R., Tudor Car L., Tufa D. G., Vasankari T. J., Vasic M., Vervoort D., Vlassov V., Vo B., Vu L. G., Waheed Y., Wamai R. G., Wang C., Wassie G. T., Wickramasinghe N. D., Yaya S., Yigit A., Yigit V., Yonemoto N., Younis M. Z., Yu C., Yunusa I., Zaki L., Zaman B. A., Zangeneh A., Zare Dehnavi A., Zastrozhin M. S., Zeng W., Zhang Z. -J., Zuhlke L. J., Zuniga Y. M. H., Hay S. I., Murray C. J. L., and Dieleman J. L.
- Abstract
Background: The COVID-19 pandemic highlighted gaps in health surveillance systems, disease prevention, and treatment globally. Among the many factors that might have led to these gaps is the issue of the financing of national health systems, especially in low-income and middle-income countries (LMICs), as well as a robust global system for pandemic preparedness. We aimed to provide a comparative assessment of global health spending at the onset of the pandemic; characterise the amount of development assistance for pandemic preparedness and response disbursed in the first 2 years of the COVID-19 pandemic; and examine expectations for future health spending and put into context the expected need for investment in pandemic preparedness. Methods: In this analysis of global health spending between 1990 and 2021, and prediction from 2021 to 2026, we estimated four sources of health spending: development assistance for health (DAH), government spending, out-of-pocket spending, and prepaid private spending across 204 countries and territories. We used the Organisation for Economic Co-operation and Development (OECD)'s Creditor Reporting System (CRS) and the WHO Global Health Expenditure Database (GHED) to estimate spending. We estimated development assistance for general health, COVID-19 response, and pandemic preparedness and response using a keyword search. Health spending estimates were combined with estimates of resources needed for pandemic prevention and preparedness to analyse future health spending patterns, relative to need. Findings: In 2019, at the onset of the COVID-19 pandemic, US$9·2 trillion (95% uncertainty interval [UI] 9·1–9·3) was spent on health worldwide. We found great disparities in the amount of resources devoted to health, with high-income countries spending $7·3 trillion (95% UI 7·2–7·4) in 2019; 293·7 times the $24·8 billion (95% UI 24·3–25·3) spent by low-income countries in 2019. That same year, $43·1 billion in development assistance was provid
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- 2023
5. Olfactory function and cognition in relapsing–remitting and secondary-progressive multiple sclerosis
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Carotenuto, A., Costabile, T., Moccia, M., Falco, F., Scala, M.R., Russo, C.V., Saccà, F., De Rosa, A., Lanzillo, R., and Brescia Morra, V.
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- 2019
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6. Exploring Interface Effects in Flatland Optics
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Moccia, M., primary, Castaldi, G., additional, Alù, A., additional, and Galdi, V., additional
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- 2023
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7. Fake news, influencers and health-related professional participation on the Web: A pilot study on a social-network of people with Multiple Sclerosis
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Lavorgna, L., De Stefano, M., Sparaco, M., Moccia, M., Abbadessa, G., Montella, P., Buonanno, D., Esposito, S., Clerico, M., Cenci, C., Trojsi, F., Lanzillo, R., Rosa, L., Morra, V. Brescia, Ippolito, D., Maniscalco, G., Bisecco, A., Tedeschi, G., and Bonavita, S.
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- 2018
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8. Why do people search Wikipedia for information on multiple sclerosis?
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Brigo, F., Lattanzi, S., Bragazzi, N., Nardone, R., Moccia, M., and Lavorgna, L.
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- 2018
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9. Spectral-Domain Method of Moments for the Study of Line Waves
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Lovat, G., primary, Fuscaldo, W., additional, Moccia, M., additional, Castaldi, G., additional, Galdi, V., additional, and Burghignoli, P., additional
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- 2023
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10. Utilization of peginterferon-β-1a in the real-world practice for relapsing-remitting multiple sclerosis.
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MOCCIA, M., SANTONI, L., VACCARI, I., AFFINITO, G., CALIENDO, D., RUBBA, F., LANZILLO, R., TRIASSI, M., MORRA, V. BRESCIA, and PALLADINO, R.
- Abstract
OBJECTIVE: Peginterferon β-1a (PEG-IFN-β-1a) is the most recent interferon beta formulation approved for treating relapsing-remitting multiple sclerosis (RRMS). We aim to describe the real-world utilization of PEG-IFN-β-1a in RRMS and compare it with other injectable disease-modifying therapies (DMTs). PATIENTS AND METHODS: In this population-based study, we used 2015-2019 routinely collected healthcare data of the Campania region of Italy from National Healthcare System DMT prescriptions, inpatient and outpatient clinical records of hospitals in Campania, and the Federico II University MS clinical registry for a subset of patients. We included individuals with RRMS receiving new prescriptions of PEG-IFN-β-1a [n=281; age = 38.8±12.3 years; females=70.5%; disease duration = 8 .4±8.3 years; Expanded Disability S tatus Scale (EDSS) at baseline=2.0 (1.0-6.5)], glatiramer acetate [n=751; age = 46.0±11.4 years; females= 67.1%; disease duration = 9.8±8.2 years; EDSS=4.0 (1.5-8.5)], and subcutaneous (SC) IFN-β-1a [n=1,226; a ge = 3 9.7±11.7 y ears; f emales= 66.5%; disease duration = 8.2±6.5 years; EDSS 2.5 (1.5-6.5)]. Adherence [medication possession ratio (MPR)], escalation to more effective DMTs, hospitalization rates and costs were measured. We used mixed-effect linear regression models (for adherence, hospitalization rates and costs) and Cox regression models (for escalation) to assess differences between PEGIFN-β-1a (statistical reference), glatiramer acetate, and SC IFN-β-1a. All models included age, sex, previous treatment/untreated, year of treatment initiation, treatment duration, and adherence as covariates. RESULTS: Adherence was lower in glatiramer acetate (MPR = 0.91±0.1; Coeff=-0.11; p<0.01), and IFN-β-1a (MPR = 0.92±0.1; Coeff=-0.08; p<0.01), compared with PEG-IFN-β-1a (MPR = 1.01±0.1). The probability of escalating to more effective DMTs was higher for glatiramer acetate (14.9%; HR=4.09; p<0.01) and IFN-β-1a (9.1%; HR=3.35; p=0.01), compared with PEG-IFN-β-1a (4.9%). No differences in annualized hospitalization rates were identified between glatiramer acetate [annualized hospitalization rates (AHR) = 0.05±0.30; Coeff=0.02; p=0.31), IFN-β-1a (AHR = 0.02±0.21; Coeff=0.01; p=0.97], and P EG-IFN-β-1a (AHR = 0 .02±0.24); h owever, monthly costs for MS admissions were higher for glatiramer acetate (€49.45±€195.27; Coeff=-29.89; p=0.03), compared with IFN-β-1a (€29.42±€47.83; Coeff=6.79; p=0.61), and PEGIFN-β-1a (€23.91±€43.90). CONCLUSIONS: SC PEG-IFN-β-1a and IFN-β-1a were used in relatively similar populations, while glatiramer acetate was preferred in older and more disabled patients. PEG-IFN-β-1a was associated with higher adherence and lower escalation rates toward more effective (and costly) DMTs. [ABSTRACT FROM AUTHOR]
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- 2024
11. MR Imaging Signs of Gadolinium Retention Are Not Associated with Long-Term Motor and Cognitive Outcomes in Multiple Sclerosis
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Scaravilli, A., primary, Tranfa, M., additional, Pontillo, G., additional, Falco, F., additional, Criscuolo, C., additional, Moccia, M., additional, Monti, S., additional, Lanzillo, R., additional, Brescia Morra, V., additional, Palma, G., additional, Petracca, M., additional, Tedeschi, E., additional, Elefante, A., additional, Brunetti, A., additional, and Cocozza, S., additional
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- 2023
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12. Engineered Acoustic Sensors for Underwater Applications Based on Coated Fiber Bragg Gratings
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Moccia, M., Pisco, M., Consales, M., Iadicicco, A., Cutolo, A., Galdi, V., Cusano, A., Baldini, Francesco, editor, D’Amico, Arnaldo, editor, Di Natale, Corrado, editor, Siciliano, Pietro, editor, Seeber, Renato, editor, De Stefano, Luca, editor, Bizzarri, Ranieri, editor, and Andò, Bruno, editor
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- 2014
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13. Signs and symptoms of COVID-19 in patients with multiple sclerosis
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Schiavetti I., Carmisciano L., Ponzano M., Cordioli C., Cocco E., Marfia G. A., Inglese M., Filippi M., Radaelli M., Bergamaschi R., Immovilli P., Capobianco M., De Rossi N., Brichetto G., Scandellari C., Cavalla P., Pesci I., Confalonieri P., Perini P., Trojano M., Lanzillo R., Tedeschi G., Comi G., Battaglia M. A., Patti F., Salvetti M., Sormani M. P., Abbadessa G., Aguglia U., Allegorico L., Rossi Allegri B. M., Alteno A., Amato M. P., Annovazzi P., Antozzi C., Appendino L., Arena S., Baione V., Balgera R., Barcella V., Baroncini D., Barrila C., Bellacosa A., Bellucci G., Bergamaschi V., Bezzini D., Biolzi B., Bisecco A., Bonavita S., Borriello G., Bosa C., Bosco A., Bovis F., Bozzali M., Brambilla L., Brescia Morra V., Buccafusca M., Bucciantini E., Bucello S., Buscarinu M. C., Cabboi M. P., Calabrese M., Calabria F., Caleri F., Camilli F., Caniatti L. M., Cantello R., Capra R., Capuano R., Carta P., Celani M. G., Cellerino M., Cerqua R., Chisari C., Clerici R., Clerico M., Cola G., Conte A., Conti M. Z., Cordano C., Cordera S., Corea F., Correale C., Cottone S., Crescenzo F., Curti E., d'Ambrosio A., D'Amico E., Danni M. C., d'Arma A., Dattola V., de Biase S., De Luca G., De Mercanti S. F., De Mitri P., De Stefano N., Della Cava F. M., Cava M. D., Di Lemme S., di Napoli M., Di Sapio A., Docimo R., Dutto A., Evangelista L., Fanara S., Fantozzi R., Ferraro D., Ferro M. T., Fioretti C., Fratta M., Frau J., Fronza M., Furlan R., Gajofatto A., Gallo A., Gallo P., Gasperini C., Ghazaryan A., Giometto B., Gobbin F., Govone F., Granella F., Grange E., Grasso M. G., Grimaldi L. M. E., Guareschi A., Guaschino C., Guerrieri S., Guidetti D., Juergenson I. B., Iaffaldano P., Ianniello A., Iasevoli L., Imperiale D., Infante M. T., Iodice R., Iovino A., Konrad G., Landi D., Lapucci C., Lavorgna L., L'Episcopo M. R., Leva S., Liberatore G., Lo Re M., Longoni M., Lopiano L., Lorefice L., Lucchini M., Lus G., Maimone D., Malentacchi M., Mallucci G., Malucchi S., Mancinelli C. R., Mancinelli L., Manganotti P., Maniscalco G. T., Mantero V., Marangoni S., Marastoni D., Marinelli F., Marti A., Boneschi Martinelli F., Masserano Z. F., Matta F., Mendozzi L., Meucci G., Miante S., Miele G., Milano E., Mirabella M., Missione R., Moccia M., Moiola L., Montepietra S., MontiBragadin M., Montini F., Motta R., Nardone R., Gabri Nicoletti C., Nobile-Orazio E., Nozzolillo A., Onofrj M., Orlandi R., Palmieri A., Paolicelli D., Pasquali L., Pasto L., Pedrazzoli E., Petracca M., Petrone A., Piantadosi C., Pietroboni A. M., Pinardi F., Portaccio E., Pozzato M., Pozzilli C., Prosperini L., Protti A., Ragonese P., Rasia S., Realmuto S., Repice A., Rigoni E., Rilla M. T., Rinaldi F., Romano C. M., Ronzoni M., Rovaris M., Ruscica F., Sabattini L., Salemi G., Saraceno L., Sartori A., Sbragia E., Scarano G. I., Scarano V., Sessa M., Sgarito C., Sibilia G., Siciliano G., Signori A., Signoriello E., Sinisi L., Sireci F., Sola P., Solaro C., Sotgiu S., Sparaco M., Stromillo M. L., Strumia S., Susani E. L., Tabiadon G., Teatini F., Tomassini V., Tonietti S., Torri V., Tortorella C., Toscano S., Totaro R., Trotta M., Turano G., Ulivelli M., Valentino M., Vaula G., Vecchio D., Vercellino M., Verrengia E. P., Vianello M., Virgilio E., Vitetta F., Vollaro S., Zaffaroni M., Zampolini M., Zarbo I. R., Zito A., Zuliani L., Schiavetti, Irene, Carmisciano, Luca, Ponzano, Marta, Cordioli, Cinzia, Cocco, Eleonora, Marfia, Girolama Alessandra, Inglese, Matilde, Filippi, Massimo, Radaelli, Marta, Bergamaschi, Roberto, Immovilli, Paolo, Capobianco, Marco, De Rossi, Nicola, Brichetto, Giampaolo, Scandellari, Cinzia, Cavalla, Paola, Pesci, Ilaria, Confalonieri, Paolo, Perini, Paola, Trojano, Maria, Lanzillo, Roberta, Tedeschi, Gioacchino, Comi, Giancarlo, Battaglia, Mario Alberto, Patti, Francesco, Salvetti, Marco, Sormani, Maria Pia, Gianmarco, Abbadessa, Umberto, Aguglia, Allegorico, Lia, Beatrice Maria Rossi Allegri, Anastasia, Alteno, Amato, MARIA PIA, Pietro, Annovazzi, Carlo, Antozzi, Lucia, Appendino, Sebastiano, Arena, Viola, Baione, Roberto, Balgera, Valeria, Barcella, Damiano, Baroncini, Caterina, Barrilà, Alessandra, Bellacosa, Gianmarco, Bellucci, Valeria, Bergamaschi, Daiana, Bezzini, Beatrice, Biolzi, Bisecco, Alvino, Simona, Bonavita, Giovanna, Borriello, Chiara, Bosa, Antonio, Bosco, Francesca, Bovi, Marco, Bozzali, Laura, Brambilla, BRESCIA MORRA, Vincenzo, Maria, Buccafusca, Elisabetta, Bucciantini, Sebastiano, Bucello, Maria Chiara Buscarinu, Maria Paola Cabboi, Massimiliano, Calabrese, Francesca, Calabria, Francesca, Caleri, Federico, Camilli, Luisa Maria Caniatti, Roberto, Cantello, Ruggero, Capra, Rocco, Capuano, Patrizia, Carta, Maria Grazia Celani, Maria, Cellerino, Raffaella, Cerqua, Clara, Chisari, Raffaella, Clerici, Marinella, Clerico, Gaia, Cola, Antonella, Conte, Marta Zaffira Conti, Christian, Cordano, Susanna, Cordera, Francesco, Corea, Claudio, Correale, Salvatore, Cottone, Francesco, Crescenzo, Erica, Curti, Alessandro, D’Ambrosio, Emanuele, D’Amico, Maura Chiara Danni, Alessia, D’Arma, Vincenzo, Dattola, Stefano de Biase, Giovanna De Luca, Stefania Federica De Mercanti, Paolo De Mitri, Nicola De Stefano, Fabio Maria Della Cava, Marco Della Cava, Sonia Di Lemme, Mario di Napoli, Alessia Di Sapio, Renato, Docimo, Anna, Dutto, Luana, Evangelista, Salvatore, Fanara, Roberta, Fantozzi, Diana, Ferraro, Maria Teresa Ferrò, Cristina, Fioretti, Mario, Fratta, Jessica, Frau, Marzia, Fronza, Roberto, Furlan, Alberto, Gajofatto, Gallo, Antonio, Paolo, Gallo, Claudio, Gasperini, Anna, Ghazaryan, Bruno, Giometto, Francesca, Gobbin, Flora, Govone, Franco, Granella, Erica, Grange, Grasso, MARIA GRAZIA, Grimaldi, Luigi M. E., Angelica, Guareschi, Clara, Guaschino, Simone, Guerrieri, Donata, Guidetti, Ina Barbara Juergenson, Pietro, Iaffaldano, Ianniello, Antonio, Luigi, Iasevoli, Daniele, Imperiale, Maria Teresa Infante, Iodice, Rosa, Iovino, Aniello, Giovanna, Konrad, Doriana, Landi, Caterina, Lapucci, Luigi, Lavorgna, Maria Rita L’Episcopo, Serena, Leva, Giuseppe, Liberatore, Marianna Lo Re, Marco, Longoni, Leonardo, Lopiano, Lorena, Lorefice, Matteo, Lucchini, Lus, Giacomo, Maimone, Davide, Maria, Malentacchi, Giulia, Mallucci, Simona, Malucchi, Chiara Rosa Mancinelli, Luca, Mancinelli, Paolo, Manganotti, Giorgia Teresa Maniscalco, Vittorio, Mantero, Sabrina, Marangoni, Damiano, Marastoni, Fabiana, Marinelli, Marti, NICOLA ALESSANDRO, Filippo Boneschi Martinelli, Zoli Federco Masserano, Francesca, Matta, Laura, Mendozzi, Giuseppe, Meucci, Silvia, Miante, Giuseppina, Miele, Eva, Milano, Massimiliano, Mirabella, Rosanna, Missione, Moccia, Marcello, Lucia, Moiola, Sara, Montepietra, Margherita, Montibragadin, Federico, Montini, Roberta, Motta, Raffaele, Nardone, Carolina Gabri Nicoletti, Eduardo, Nobile‐orazio, Nozzolillo, Agostino, Marco, Onofrj, Riccardo, Orlandi, Anna, Palmieri, Damiano, Paolicelli, Livia, Pasquali, Luisa, Pastò, Elisabetta, Pedrazzoli, Petracca, Maria, Alfredo, Petrone, Carlo, Piantadosi, Pietroboni, Anna M., Federica, Pinardi, Emilio, Portaccio, Mattia, Pozzato, Pozzilli, Carlo, Luca, Prosperini, Alessandra, Protti, Paolo, Ragonese, Sarah, Rasia, Sabrina, Realmuto, Anna, Repice, Eleonora, Rigoni, Maria Teresa Rilla, DELLA RATTA RINALDI, Francesca, Calogero Marcello Romano, Marco, Ronzoni, Marco, Rovari, Francesca, Ruscica, Loredana, Sabattini, Giuseppe, Salemi, Lorenzo, Saraceno, Alessia, Sartori, Arianna, Sartori, Elvira, Sbragia, Giuditta Ilaria Scarano, Valentina, Scarano, Maria, Sessa, Caterina, Sgarito, Sibilia, Grazia, Gabriele, Siciliano, Alessio, Signori, Signoriello, Elisabetta, Sinisi, Leonardo, Francesca, Sireci, Patrizia, Sola, Claudio, Solaro, Stefano, Sotgiu, Maddalena, Sparaco, Maria Laura Stromillo, Silvia, Strumia, Emanuela Laura Susani, Giulietta, Tabiadon, Francesco, Teatini, Valentina, Tomassini, Simone, Tonietti, Valentina, Torri, Tortorella, Carla, Simona, Toscano, Rocco, Totaro, Maria, Trotta, Gabriella, Turano, Monica, Ulivelli, Manzo, Valentino, Giovanna, Vaula, Domizia, Vecchio, Marco, Vercellino, Elena Pinuccia Verrengia, Marika, Vianello, Eleonora, Virgilio, Francesca, Vitetta, Vollaro, Stefano, Mauro, Zaffaroni, Mauro, Zampolini, Ignazio Roberto Zarbo, Antonio, Zito, and Luigi Zuliani, Schiavetti, I., Carmisciano, L., Ponzano, M., Cordioli, C., Cocco, E., Marfia, G. A., Inglese, M., Filippi, M., Radaelli, M., Bergamaschi, R., Immovilli, P., Capobianco, M., De Rossi, N., Brichetto, G., Scandellari, C., Cavalla, P., Pesci, I., Confalonieri, P., Perini, P., Trojano, M., Lanzillo, R., Tedeschi, G., Comi, G., Battaglia, M. A., Patti, F., Salvetti, M., Sormani, M. P., Abbadessa, G., Aguglia, U., Allegorico, L., Rossi Allegri, B. M., Alteno, A., Amato, M. P., Annovazzi, P., Antozzi, C., Appendino, L., Arena, S., Baione, V., Balgera, R., Barcella, V., Baroncini, D., Barrila, C., Bellacosa, A., Bellucci, G., Bergamaschi, V., Bezzini, D., Biolzi, B., Bisecco, A., Bonavita, S., Borriello, G., Bosa, C., Bosco, A., Bovis, F., Bozzali, M., Brambilla, L., Brescia Morra, V., Buccafusca, M., Bucciantini, E., Bucello, S., Buscarinu, M. C., Cabboi, M. P., Calabrese, M., Calabria, F., Caleri, F., Camilli, F., Caniatti, L. M., Cantello, R., Capra, R., Capuano, R., Carta, P., Celani, M. G., Cellerino, M., Cerqua, R., Chisari, C., Clerici, R., Clerico, M., Cola, G., Conte, A., Conti, M. Z., Cordano, C., Cordera, S., Corea, F., Correale, C., Cottone, S., Crescenzo, F., Curti, E., D'Ambrosio, A., D'Amico, E., Danni, M. C., D'Arma, A., Dattola, V., de Biase, S., De Luca, G., De Mercanti, S. F., De Mitri, P., De Stefano, N., Della Cava, F. M., Cava, M. D., Di Lemme, S., di Napoli, M., Di Sapio, A., Docimo, R., Dutto, A., Evangelista, L., Fanara, S., Fantozzi, R., Ferraro, D., Ferro, M. T., Fioretti, C., Fratta, M., Frau, J., Fronza, M., Furlan, R., Gajofatto, A., Gallo, A., Gallo, P., Gasperini, C., Ghazaryan, A., Giometto, B., Gobbin, F., Govone, F., Granella, F., Grange, E., Grasso, M. G., Grimaldi, L. M. E., Guareschi, A., Guaschino, C., Guerrieri, S., Guidetti, D., Juergenson, I. B., Iaffaldano, P., Ianniello, A., Iasevoli, L., Imperiale, D., Infante, M. T., Iodice, R., Iovino, A., Konrad, G., Landi, D., Lapucci, C., Lavorgna, L., L'Episcopo, M. R., Leva, S., Liberatore, G., Lo Re, M., Longoni, M., Lopiano, L., Lorefice, L., Lucchini, M., Lus, G., Maimone, D., Malentacchi, M., Mallucci, G., Malucchi, S., Mancinelli, C. R., Mancinelli, L., Manganotti, P., Maniscalco, G. T., Mantero, V., Marangoni, S., Marastoni, D., Marinelli, F., Marti, A., Boneschi Martinelli, F., Masserano, Z. F., Matta, F., Mendozzi, L., Meucci, G., Miante, S., Miele, G., Milano, E., Mirabella, M., Missione, R., Moccia, M., Moiola, L., Montepietra, S., Montibragadin, M., Montini, F., Motta, R., Nardone, R., Gabri Nicoletti, C., Nobile-Orazio, E., Nozzolillo, A., Onofrj, M., Orlandi, R., Palmieri, A., Paolicelli, D., Pasquali, L., Pasto, L., Pedrazzoli, E., Petracca, M., Petrone, A., Piantadosi, C., Pietroboni, A. M., Pinardi, F., Portaccio, E., Pozzato, M., Pozzilli, C., Prosperini, L., Protti, A., Ragonese, P., Rasia, S., Realmuto, S., Repice, A., Rigoni, E., Rilla, M. T., Rinaldi, F., Romano, C. M., Ronzoni, M., Rovaris, M., Ruscica, F., Sabattini, L., Salemi, G., Saraceno, L., Sartori, A., Sbragia, E., Scarano, G. I., Scarano, V., Sessa, M., Sgarito, C., Sibilia, G., Siciliano, G., Signori, A., Signoriello, E., Sinisi, L., Sireci, F., Sola, P., Solaro, C., Sotgiu, S., Sparaco, M., Stromillo, M. L., Strumia, S., Susani, E. L., Tabiadon, G., Teatini, F., Tomassini, V., Tonietti, S., Torri, V., Tortorella, C., Toscano, S., Totaro, R., Trotta, M., Turano, G., Ulivelli, M., Valentino, M., Vaula, G., Vecchio, D., Vercellino, M., Verrengia, E. P., Vianello, M., Virgilio, E., Vitetta, F., Vollaro, S., Zaffaroni, M., Zampolini, M., Zarbo, I. R., Zito, A., and Zuliani, L.
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Multiple Sclerosis ,Anosmia ,Clinical Sciences ,neurological disorders ,Neurodegenerative ,Settore MED/26 ,demyelinating disease ,COVID-19 ,demyelinating diseases ,disease-modifying treatment ,multiple sclerosis ,Humans ,neurological disorder ,Aged ,Neurology & Neurosurgery ,SARS-CoV-2 ,Pain Research ,Neurosciences ,Brain Disorders ,Settore MED/26 - NEUROLOGIA ,Good Health and Well Being ,Neurology ,multiple sclerosi ,Neurology (clinical) ,MuSC-19 Study Group ,Ageusia ,Human - Abstract
Background and purpose: Clinical outcomes of multiple sclerosis (MS) patients affected by coronavirus disease 2019 (COVID-19) have been thoroughly investigated, but a further analysis on main signs and symptoms and their risk factors still needs attention. The objective of this study was to group together and describe based on similarity the most common signs and symptoms of COVID-19 in MS patients and identify all factors associated with their manifestation. Method: Logistic and linear regression models were run to recognize factors associated with each pooled group of symptoms and their total number. Results: From March 2020 to November 2021, data were collected from 1354 MS patients with confirmed infection of COVID-19. Ageusia and anosmia was less frequent in older people (odds ratio [OR] 0.98; p=0.005) and more in smoker patients (OR 1.39; p=0.049). Smoke was also associated with an incremental number of symptoms (OR 1.24; p=0.031), substance abuse (drugs or alcohol), conjunctivitis and rash (OR 5.20; p=0.042) and the presence of at least one comorbidity with shortness of breath, tachycardia or chest pain (OR 1.24; p=0.008). Some disease-modifying therapies were associated with greater frequencies of certain COVID-19 symptoms (association between anti-CD20 therapies and increment in the number of concomitant symptoms: OR 1.29; p=0.05). Differences in frequencies between the three waves were found for flu-like symptoms (G1, p=0.024), joint or muscle pain (G2, p=0.013) and ageusia and anosmia (G5, p < 0.001). All cases should be referred to variants up to Delta. Conclusion: Several factors along with the choice of specific therapeutic approaches might have a different impact on the occurrence of some COVID-19 symptoms.
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- 2022
14. Association between institutional affiliations of academic editors and authors in medical journals
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Palladino, R, primary, Alfano, R, additional, Moccia, M, additional, Barone-Adesi, F, additional, Majeed, A, additional, Triassi, M, additional, and Millett, C, additional
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- 2022
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15. Recent Advances and Perspectives in Line-Wave Electromagnetics
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Moccia, M., primary, Castaldi, G., additional, and Galdi, V., additional
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- 2022
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16. Redistribution of garbage codes to underlying causes of death: a systematic analysis on Italy and a comparison with most populous Western European countries based on the Global Burden of Disease Study 2019 (Jan, 10.1093/eurpub/ckab194, 2022)
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Monasta, L, Alicandro, G, Pasovic, M, Cunningham, M, Armocida, B, Albano, L, Beghi, E, Beghi, M, Bosetti, C, Bragazzi, NL, Carreras,G, Castelpietra, G, Alberico, L, Cattaruzza,MS, Collatuzzo,G, Conti, S, Damiani, G, Ferrara, P, Fornari,C, Gallus, S, Giampaoli,S, Golinelli, D, Isola, G, Lauriola, C, La Vecchia, C, Leonardi, M, Magnani, FG, Minelli, G, Moccia, M, Pedersini, P, Perico, N, Raggi, A, Remuzzi, G, Sanmarchi, F, Sattin, D, Unim, B, Villafañe, JH, Violante, FS, Murray, CJL, Ronfani, L, Naghavi, M, Monasta, L, Alicandro, G, Pasovic, M, Cunningham, M, Armocida, B, Albano, L, Beghi, E, Beghi, M, Bosetti, C, Bragazzi, Nl, Carreras, G, Castelpietra, G, Alberico, L, Cattaruzza, M, Collatuzzo, G, Conti, S, Damiani, G, Ferrara, P, Fornari, C, Gallus, S, Giampaoli, S, Golinelli, D, Isola, G, Lauriola, C, La Vecchia, C, Leonardi, M, Magnani, Fg, Minelli, G, Moccia, M, Pedersini, P, Perico, N, Raggi, A, Remuzzi, G, Sanmarchi, F, Sattin, D, Unim, B, Villafañe, Jh, Violante, F, Murray, Cjl, Ronfani, L, and Naghavi, M
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heterogeneity cause of death ,global burden of disease ,ischemic stroke diabetes mellitus type 2 ,garbage glasgow coma scale ,italy - Abstract
In the originally published version of this manuscript, an author was erroneously omitted from the list of authors. The list should read: “Lorenzo Monasta, Gianfranco Alicandro, Maja Pasovic, Matthew Cunningham, Benedetta Armocida, Christopher J L Murray, Luca Ronfani, Mohsen Naghavi, GBD 2019 Italy Causes of Death Collaborators” instead of “Lorenzo Monasta, Gianfranco Alicandro, Maja Pasovic, Matthew Cunningham, Benedetta Armocida, Luca Ronfani, Mohsen Naghavi, GBD 2019 Italy Causes of Death Collaborators”. This error has been corrected online.
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- 2022
17. Telemedicine for management of patients with amyotrophic lateral sclerosis through COVID-19 tail
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Bombaci, A, Abbadessa, G, Trojsi, F, Leocani, L, Bonavita, S, Lavorgna, L, Tedeschi, G, Mancardi, G, Padovani, A, Clerico, M, Brigo, F, Lanzillo, R, Russo, A, Giometto, B, Straccia, G, Iodice, R, Bucello, S, Annovazzi, P, Moccia, M, Prosperini, L, Stromillo, M, Repice, A, Miele, G, Lerario, A, De Martino, A, Iodice, F, Di Lorenzo, F, Cuffaro, L, Romoli, M, Silvestro, M, Artusi, C, Bombaci A., Abbadessa G., Trojsi F., Leocani L., Bonavita S., Lavorgna L., Tedeschi G., Mancardi G., Padovani A., Clerico M., Brigo F., Lanzillo R., Russo A., Giometto B., Straccia G., Iodice R., Bucello S., Annovazzi P., Moccia M., Prosperini L., Stromillo M. L., Repice A. M., Miele G., Lerario A., De Martino A., Iodice F., Di Lorenzo F., Cuffaro L., Romoli M., Silvestro M., Artusi C. A., Bombaci, A, Abbadessa, G, Trojsi, F, Leocani, L, Bonavita, S, Lavorgna, L, Tedeschi, G, Mancardi, G, Padovani, A, Clerico, M, Brigo, F, Lanzillo, R, Russo, A, Giometto, B, Straccia, G, Iodice, R, Bucello, S, Annovazzi, P, Moccia, M, Prosperini, L, Stromillo, M, Repice, A, Miele, G, Lerario, A, De Martino, A, Iodice, F, Di Lorenzo, F, Cuffaro, L, Romoli, M, Silvestro, M, Artusi, C, Bombaci A., Abbadessa G., Trojsi F., Leocani L., Bonavita S., Lavorgna L., Tedeschi G., Mancardi G., Padovani A., Clerico M., Brigo F., Lanzillo R., Russo A., Giometto B., Straccia G., Iodice R., Bucello S., Annovazzi P., Moccia M., Prosperini L., Stromillo M. L., Repice A. M., Miele G., Lerario A., De Martino A., Iodice F., Di Lorenzo F., Cuffaro L., Romoli M., Silvestro M., and Artusi C. A.
- Abstract
Over the last months, due to coronavirus disease (COVID-19) pandemic, containment measures have led to important social restriction. Healthcare systems have faced a complete rearrangement of resources and spaces, with the creation of wards devoted to COVID-19 patients. In this context, patients affected by chronic neurological diseases, such as amyotrophic lateral sclerosis (ALS), are at risk to be lost at follow-up, leading to a higher risk of morbidity and mortality. Telemedicine may allow meet the needs of these patients. In this commentary, we briefly discuss the digital tools to remotely monitor and manage ALS patients. Focusing on detecting disease progression and preventing life-threatening conditions, we propose a toolset able to improve ALS management during this unprecedented situation.
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- 2021
18. JC virus antibody index in natalizumab-treated patients: correlations with John Cunningham virus DNA and C-reactive protein level
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Lanzillo R, Liuzzi R, Vallefuoco L, Moccia M, Amato L, Vacca G, Vacchiano V, Portella G, and Brescia Morra V
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Therapeutics. Pharmacology ,RM1-950 - Abstract
Roberta Lanzillo,1 Raffaele Liuzzi,2 Luca Vallefuoco,3 Marcello Moccia,1 Luca Amato,1 Giovanni Vacca,1 Veria Vacchiano,1 Giuseppe Portella,3 Vincenzo Brescia Morra1 1Neurological Sciences Department, Federico II University, 2Institute of Biostructure and Bioimaging, National Research Council, 3Clinical Pathology Department, Federico II University, Naples, ItalyAbstract: Natalizumab-treated patients have a higher risk of developing progressive multifocal leukoencephalopathy. Exposure to John Cunningham virus (JCV) is a prerequisite for PML (progressive multifocal leukoencephalopathy). To assess JCV exposure in multiple sclerosis patients, we performed a serological examination, obtained the antibody index, performed real-time polymerase chain reaction (PCR) to detect JCV DNA in plasma and urine, and investigated the role of ultrasensitive C-reactive protein (usCRP) as a possible biological marker of JCV reactivation. We retrospectively analyzed consecutive natalizumab-treated multiple sclerosis patients who underwent a JCV antibody test through a two-step enzyme-linked immunosorbent assay (STRATIFY test) to the measure of serum usCRP levels, and to perform blood and urine JCV PCR. The studied cohort included 97 relapsing–remitting patients (60 women). Fifty-two patients (53.6%) tested positive for anti-JCV antibodies. PCR showed JCV DNA in the urine of 30 out of 83 (36.1%) patients and 28 out of 44 seropositive patients (63.6%), with a 6.7% false-negative rate for the STRATIFY test. Normalized optical density values were higher in urinary JCV DNA-positive patients (P
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- 2014
19. Mode coupling and field distribution in sub-mm permanently bent single mode optical fibers
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Iadicicco, A., Paladino, D., Moccia, M., Quero, G., Campopiano, S., Bock, W.J., and Cusano, A.
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- 2013
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20. Population-level risks of alcohol consumption by amount, geography, age, sex, and year: a systematic analysis for the Global Burden of Disease Study 2020
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Bryazka, D, Reitsma, MB, Griswold, MG, Abate, KH, Abbafati, C, Kangevari, MA, Kangevari, ZA, Abdoli, A, Abdollahi, M, Abdullah, AYM, Abhilash, ES, Abu Gharbieh, E, Acuna, JM, Addolorato, G, Adebayo, OM, Adekanmbi, V, Adhikari, K, Adhikari, S, Adnani, QES, Afzal, S, Agegnehu, WY, Aggarwal, M, Ahinkorah, BO, Ahmad, AR, Ahmad, S, Ahmad, T, Ahmadi, A, Ahmadi, S, Ahmed, H, Rashid, TA, Akunna, CJ, Al Hamad, H, Alam, MZ, Alem, DT, Alene, KA, Alimohamadi, Y, Alizadeh, A, Allel, K, Alonso, J, Alvand, S, Guzman, NA, Amare, F, Ameyaw, EK, Amiri, S, Ancuceanu, R, Anderson, JA, Andrei, CL, Andrei, T, Arabloo, J, Arshad, M, Artamonov, AA, Aryan, Z, Asaad, M, Asemahagn, MA, Burt, TA, Athari, SS, Atnafu, DD, Atorkey, P, Atreya, A, Ausloos, F, Ausloos, M, Ayano, G, Ayanore, MA, Ayinde, OO, Mateos, JLA, Azadnajafabad, S, Azanaw, MM, Khyavy, MA, Jafari, AA, Azzam, AY, Badiye, AD, Bagheri, N, Bagherieh, S, Bairwa, M, Bakkannavar, SM, Bakshi, RK, Balchut, AH, Null, T, Barra, F, Barrow, A, Baskaran, P, Belo, L, Bennett, DA, Bensenor, IM, Bhagavathula, AS, Bhala, N, Bhalla, A, Bhardwaj, N, Bhardwaj, P, Bhaskar, S, Bhattacharyya, K, Bhojaraja, VS, Bintoro, BS, Blokhina, EAE, Bodicha, BBA, Boloor, A, Bosetti, C, Braithwaite, D, Brenner, H, Briko, NI, Brunoni, AR, Butt, ZA, Cao, C, Cao, Y, Cardenas, R, Carvalho, AF, Carvalho, M, Maia, JMC, Castelpietra, G, de Araujo, LFSC, Cattaruzza, MS, Chakraborty, PA, Charan, J, Chattu, VK, Chaurasia, A, Cherbuin, N, Dinh, TC, Chudal, N, Chung, SC, Churko, C, Ciobanu, LG, Cirillo, M, Claro, RM, Costanzo, S, Cowden, RG, Criqui, MH, Martins, NC, Culbreth, GT, Dachew, BA, Dadras, O, Dai, X, Damiani, G, Dandona, L, Dandona, R, Daniel, BD, Danielewicz, A, Gela, JD, Davletov, K, de Araujo, JAP, de Sa Junior, AR, Debela, SA, Dehghan, A, Demetriades, AK, Molla, MD, Desai, R, Desta, AA, da Silva, DD, Diaz, D, Digesa, LE, Diress, M, Dodangeh, M, Dongarwar, D, Dorostkar, F, Dsouza, HL, Duko, B, Duncan, BB, Edvardsson, K, Ekholuenetale, M, Elgar, FJ, Elhadi, M, Elmonem, MA, Endries, AY, Eskandarieh, S, Etemadimanesh, A, Fagbamigbe, AF, Fakhradiyev, IR, Farahmand, F, Sa Farinha, CSE, Faro, A, Farzadfar, F, Fatehizadeh, A, Fauk, NK, Feigin, VL, Feldman, R, Feng, X, Fentaw, Z, Ferrero, S, Desideri, LF, Filip, I, Fischer, F, Francis, JM, Franklin, RC, Gaal, PA, Gad, MM, Gallus, S, Galvano, F, Ganesan, B, Garg, T, Gebrehiwot, MGD, Gebremeskel, TG, Gebremichael, MA, Gemechu, TR, Getacher, L, Getachew, ME, Obsa, AG, Getie, A, Ghaderi, A, Ghafourifard, M, Ghajar, A, Ghamari, SH, Ghandour, LA, Nour, MG, Ghashghaee, A, Ghozy, S, Glozah, FN, Glushkova, EV, Godos, J, Goel, A, Goharinezhad, S, Golechha, M, Goleij, P, Golitaleb, M, Greaves, F, Grivna, M, Grosso, G, Gudayu, TW, Gupta, B, Gupta, R, Gupta, S, Gupta, VB, Gupta, VK, Nejad, NH, Mirzaian, AH, Hall, BJ, Halwani, R, Handiso, TB, Hankey, GJ, Hariri, S, Haro, JM, Hasaballah, A, Moghaddam, HH, Hay, S, Hayat, K, Heidari, G, Heidari, M, Hendrie, D, Herteliu, C, Heyi, DZ, Hezam, K, Hlongwa, MM, Holla, R, Hossain, MM, Hossain, S, Hosseini, SK, Hosseinzadeh, M, Hostiuc, M, Hostiuc, S, Hu, G, Huang, J, Hussain, S, Ibitoye, SE, Ilic, IM, Ilic, MD, Immurana, M, Irham, LM, Islam, MM, Islam, RM, Islam, SMS, Iso, H, Itumalla, R, Iwagami, M, Jabbarinejad, R, Jacob, L, Jakovljevic, M, Jamalpoor, Z, Jamshidi, E, Jayapal, SK, Jayarajah, UU, Jayawardena, R, Jebai, R, Jeddi, SA, Jema, AT, Jha, RP, Jindal, HA, Jonas, JB, Joo, T, Joseph, N, Joukar, F, Jozwiak, JJ, Jurisson, M, Kabir, A, Kabthymer, RH, Kamble, BD, Kandel, H, Kanno, GG, Kapoor, N, Karaye, IM, Karimi, SE, Kassa, BG, Kaur, RJ, Kayode, GA, Keykhaei, M, Khajuria, H, Khalilov, R, Khan, IA, Ab Khan, M, Kim, H, Kim, J, Kim, MS, Kimokoti, RW, Kivimaki, M, Klymchuk, V, Knudsen, AKS, Kolahi, AA, Korshunov, VA, Koyanagi, A, Krishan, K, Krishnamoorthy, Y, Kumar, GA, Kumar, N, Ben, L, Lallukka, T, Lasrado, S, Lau, J, Lee, SW, Lee, WC, Lee, YH, Lim, LL, Lim, SS, Lobo, SW, Lopukhov, PD, Lorkowski, S, Lozano, R, Lucchetti, G, Madadizadeh, F, Mahjoub, S, Mahmoodpoor, A, Mahumud, RA, Makki, A, Malekpour, MR, Manjunatha, N, Mansouri, B, Mansournia, MA, Raga, JM, Villa, FAM, Matzopoulos, R, Maulik, PK, Mayeli, M, McGrath, JJ, Meena, JK, Nasab, EM, Menezes, RG, Mensink, GBM, Mentis, AFA, Meretoja, A, Merga, BT, Mestrovic, T, Jonasson, JM, Miazgowski, B, de Sa, ACMGN, Miller, TR, Mini, G, Mirica, A, Mirijello, A, Mirmoeeni, S, Mirrakhimov, EM, Misra, S, Moazen, B, Mobarakabadi, M, Moccia, M, Mohammad, Y, Mohammadi, E, Hafshejani, AM, Mohammed, TA, Moka, N, Mokdad, AH, Momtazmanesh, S, Moradi, Y, Mostafavi, E, Mubarik, S, Mullany, EC, Mulugeta, BT, Zamora, EM, Murray, CJL, Mwita, JC, Naghavi, M, Naimzada, MD, Nangia, V, Nayak, BP, Negoi, I, Negoi, RI, Nejadghaderi, SA, Nepal, S, Neupane, SPP, Kandel, SN, Nigatu, YT, Nowroozi, A, Nuruzzaman, KM, Nzoputam, CI, Obamiro, KO, Ogbo, FA, Oguntade, AS, Aliabad, HO, Olakunde, BO, Oliveira, GMM, Bali, AO, Omer, E, Altamirano, DVO, Otoiu, A, Otstavnov, SS, Oumer, B, Mahesh, PA, Monedero, AP, Palladino, R, Pana, A, Jonas, SP, Pandey, A, Pardhan, S, Parekh, T, Park, EK, Parry, CDH, Kan, FP, Patel, J, Pati, S, Patton, GC, Paudel, U, Pawar, S, Peden, AE, Petcu, IR, Phillips, MR, Pinheiro, M, Plotnikov, E, Pradhan, PMS, Prashant, A, Quan, J, Radfar, A, Rafiei, A, Raghav, PR, Movaghar, VR, Rahman, A, Rahman, MM, Rahman, M, Rahmani, AM, Rahmani, S, Ranabhat, CL, Ranasinghe, P, Rao, CR, Rasali, DP, Rashidi, MM, Ratan, ZA, Rawaf, DL, Rawaf, S, Rawal, L, Renzaho, AMN, Rezaei, N, Rezaei, S, Rezaeian, M, Riahi, SM, Rodriguez, ER, Roth, GA, Rwegerera, GM, Saddik, B, Sadeghi, E, Sadeghian, R, Saeed, U, Saeedi, F, Sagar, R, Sahebkar, A, Sahoo, H, Sahraian, MA, Rahman, KSU, Salahi, S, Salimzadeh, H, Samy, AM, Sanmarchi, F, Milicevic, MMS, Sarikhani, Y, Sathian, B, Saya, GK, Sayyah, M, Schmidt, MI, Schutte, AE, Schwarzinger, M, Schwebel, DC, Seidu, AA, Kumar, NS, SeyedAlinaghi, S, Seylani, A, Sha, F, Shahin, S, Sanavi, FS, Shahrokhi, S, Shaikh, MA, Shaker, E, Shakhmardanov, MZ, Beyranvand, MS, Sheikhbahaei, S, Sheikhi, RA, Shetty, A, Shetty, JK, Shiferaw, DS, Shigematsu, M, Shiri, R, Shirkoohi, R, Shivakumar, KM, Shivarov, V, Shobeiri, P, Shrestha, R, Sidemo, NB, Sigfusdottir, ID, Silva, DAS, da Silva, NT, Singh, JA, Singh, S, Skryabin, VY, Skryabina, AA, Sleet, DA, Solmi, M, Solomon, Y, Song, S, Song, Y, Sorensen, RJD, Soshnikov, S, Soyiri, IN, Stein, DJ, Subba, SH, Szocska, M, Seisdedos, RT, Tabuchi, T, Taheri, M, Tan, KK, Tareke, M, Tarkang, EE, Temesgen, G, Temesgen, WA, Temsah, MH, Thankappan, KR, Thapar, R, Thomas, NK, Tiruneh, C, Todorovic, J, Torrado, M, Touvier, M, Palone, MRT, Mai, TNT, Llimos, ST, Tripathy, JP, Vakilian, A, Valizadeh, R, Varmaghani, M, Varthya, SB, Vasankari, TJ, Vos, T, Wagaye, B, Waheed, Y, Walde, MT, Wang, C, Wang, Y, Wang, YP, Westerman, R, Wickramasinghe, ND, Wubetu, AD, Xu, S, Yamagishi, K, Yang, L, Yesera, GEE, Yigit, A, Yigit, V, Yimaw, AE, Yon, DK, Yonemoto, N, Yu, C, Zadey, S, Zahir, M, Zare, I, Zastrozhin, MS, Zastrozhina, A, Zhang, ZJ, Zhong, C, Zmaili, M, Zuniga, YMH, Gakidou, E, Madureira-Carvalho, AM, Bryazka, D, Reitsma, MB, Griswold, MG, Abate, KH, Abbafati, C, Kangevari, MA, Kangevari, ZA, Abdoli, A, Abdollahi, M, Abdullah, AYM, Abhilash, ES, Abu Gharbieh, E, Acuna, JM, Addolorato, G, Adebayo, OM, Adekanmbi, V, Adhikari, K, Adhikari, S, Adnani, QES, Afzal, S, Agegnehu, WY, Aggarwal, M, Ahinkorah, BO, Ahmad, AR, Ahmad, S, Ahmad, T, Ahmadi, A, Ahmadi, S, Ahmed, H, Rashid, TA, Akunna, CJ, Al Hamad, H, Alam, MZ, Alem, DT, Alene, KA, Alimohamadi, Y, Alizadeh, A, Allel, K, Alonso, J, Alvand, S, Guzman, NA, Amare, F, Ameyaw, EK, Amiri, S, Ancuceanu, R, Anderson, JA, Andrei, CL, Andrei, T, Arabloo, J, Arshad, M, Artamonov, AA, Aryan, Z, Asaad, M, Asemahagn, MA, Burt, TA, Athari, SS, Atnafu, DD, Atorkey, P, Atreya, A, Ausloos, F, Ausloos, M, Ayano, G, Ayanore, MA, Ayinde, OO, Mateos, JLA, Azadnajafabad, S, Azanaw, MM, Khyavy, MA, Jafari, AA, Azzam, AY, Badiye, AD, Bagheri, N, Bagherieh, S, Bairwa, M, Bakkannavar, SM, Bakshi, RK, Balchut, AH, Null, T, Barra, F, Barrow, A, Baskaran, P, Belo, L, Bennett, DA, Bensenor, IM, Bhagavathula, AS, Bhala, N, Bhalla, A, Bhardwaj, N, Bhardwaj, P, Bhaskar, S, Bhattacharyya, K, Bhojaraja, VS, Bintoro, BS, Blokhina, EAE, Bodicha, BBA, Boloor, A, Bosetti, C, Braithwaite, D, Brenner, H, Briko, NI, Brunoni, AR, Butt, ZA, Cao, C, Cao, Y, Cardenas, R, Carvalho, AF, Carvalho, M, Maia, JMC, Castelpietra, G, de Araujo, LFSC, Cattaruzza, MS, Chakraborty, PA, Charan, J, Chattu, VK, Chaurasia, A, Cherbuin, N, Dinh, TC, Chudal, N, Chung, SC, Churko, C, Ciobanu, LG, Cirillo, M, Claro, RM, Costanzo, S, Cowden, RG, Criqui, MH, Martins, NC, Culbreth, GT, Dachew, BA, Dadras, O, Dai, X, Damiani, G, Dandona, L, Dandona, R, Daniel, BD, Danielewicz, A, Gela, JD, Davletov, K, de Araujo, JAP, de Sa Junior, AR, Debela, SA, Dehghan, A, Demetriades, AK, Molla, MD, Desai, R, Desta, AA, da Silva, DD, Diaz, D, Digesa, LE, Diress, M, Dodangeh, M, Dongarwar, D, Dorostkar, F, Dsouza, HL, Duko, B, Duncan, BB, Edvardsson, K, Ekholuenetale, M, Elgar, FJ, Elhadi, M, Elmonem, MA, Endries, AY, Eskandarieh, S, Etemadimanesh, A, Fagbamigbe, AF, Fakhradiyev, IR, Farahmand, F, Sa Farinha, CSE, Faro, A, Farzadfar, F, Fatehizadeh, A, Fauk, NK, Feigin, VL, Feldman, R, Feng, X, Fentaw, Z, Ferrero, S, Desideri, LF, Filip, I, Fischer, F, Francis, JM, Franklin, RC, Gaal, PA, Gad, MM, Gallus, S, Galvano, F, Ganesan, B, Garg, T, Gebrehiwot, MGD, Gebremeskel, TG, Gebremichael, MA, Gemechu, TR, Getacher, L, Getachew, ME, Obsa, AG, Getie, A, Ghaderi, A, Ghafourifard, M, Ghajar, A, Ghamari, SH, Ghandour, LA, Nour, MG, Ghashghaee, A, Ghozy, S, Glozah, FN, Glushkova, EV, Godos, J, Goel, A, Goharinezhad, S, Golechha, M, Goleij, P, Golitaleb, M, Greaves, F, Grivna, M, Grosso, G, Gudayu, TW, Gupta, B, Gupta, R, Gupta, S, Gupta, VB, Gupta, VK, Nejad, NH, Mirzaian, AH, Hall, BJ, Halwani, R, Handiso, TB, Hankey, GJ, Hariri, S, Haro, JM, Hasaballah, A, Moghaddam, HH, Hay, S, Hayat, K, Heidari, G, Heidari, M, Hendrie, D, Herteliu, C, Heyi, DZ, Hezam, K, Hlongwa, MM, Holla, R, Hossain, MM, Hossain, S, Hosseini, SK, Hosseinzadeh, M, Hostiuc, M, Hostiuc, S, Hu, G, Huang, J, Hussain, S, Ibitoye, SE, Ilic, IM, Ilic, MD, Immurana, M, Irham, LM, Islam, MM, Islam, RM, Islam, SMS, Iso, H, Itumalla, R, Iwagami, M, Jabbarinejad, R, Jacob, L, Jakovljevic, M, Jamalpoor, Z, Jamshidi, E, Jayapal, SK, Jayarajah, UU, Jayawardena, R, Jebai, R, Jeddi, SA, Jema, AT, Jha, RP, Jindal, HA, Jonas, JB, Joo, T, Joseph, N, Joukar, F, Jozwiak, JJ, Jurisson, M, Kabir, A, Kabthymer, RH, Kamble, BD, Kandel, H, Kanno, GG, Kapoor, N, Karaye, IM, Karimi, SE, Kassa, BG, Kaur, RJ, Kayode, GA, Keykhaei, M, Khajuria, H, Khalilov, R, Khan, IA, Ab Khan, M, Kim, H, Kim, J, Kim, MS, Kimokoti, RW, Kivimaki, M, Klymchuk, V, Knudsen, AKS, Kolahi, AA, Korshunov, VA, Koyanagi, A, Krishan, K, Krishnamoorthy, Y, Kumar, GA, Kumar, N, Ben, L, Lallukka, T, Lasrado, S, Lau, J, Lee, SW, Lee, WC, Lee, YH, Lim, LL, Lim, SS, Lobo, SW, Lopukhov, PD, Lorkowski, S, Lozano, R, Lucchetti, G, Madadizadeh, F, Mahjoub, S, Mahmoodpoor, A, Mahumud, RA, Makki, A, Malekpour, MR, Manjunatha, N, Mansouri, B, Mansournia, MA, Raga, JM, Villa, FAM, Matzopoulos, R, Maulik, PK, Mayeli, M, McGrath, JJ, Meena, JK, Nasab, EM, Menezes, RG, Mensink, GBM, Mentis, AFA, Meretoja, A, Merga, BT, Mestrovic, T, Jonasson, JM, Miazgowski, B, de Sa, ACMGN, Miller, TR, Mini, G, Mirica, A, Mirijello, A, Mirmoeeni, S, Mirrakhimov, EM, Misra, S, Moazen, B, Mobarakabadi, M, Moccia, M, Mohammad, Y, Mohammadi, E, Hafshejani, AM, Mohammed, TA, Moka, N, Mokdad, AH, Momtazmanesh, S, Moradi, Y, Mostafavi, E, Mubarik, S, Mullany, EC, Mulugeta, BT, Zamora, EM, Murray, CJL, Mwita, JC, Naghavi, M, Naimzada, MD, Nangia, V, Nayak, BP, Negoi, I, Negoi, RI, Nejadghaderi, SA, Nepal, S, Neupane, SPP, Kandel, SN, Nigatu, YT, Nowroozi, A, Nuruzzaman, KM, Nzoputam, CI, Obamiro, KO, Ogbo, FA, Oguntade, AS, Aliabad, HO, Olakunde, BO, Oliveira, GMM, Bali, AO, Omer, E, Altamirano, DVO, Otoiu, A, Otstavnov, SS, Oumer, B, Mahesh, PA, Monedero, AP, Palladino, R, Pana, A, Jonas, SP, Pandey, A, Pardhan, S, Parekh, T, Park, EK, Parry, CDH, Kan, FP, Patel, J, Pati, S, Patton, GC, Paudel, U, Pawar, S, Peden, AE, Petcu, IR, Phillips, MR, Pinheiro, M, Plotnikov, E, Pradhan, PMS, Prashant, A, Quan, J, Radfar, A, Rafiei, A, Raghav, PR, Movaghar, VR, Rahman, A, Rahman, MM, Rahman, M, Rahmani, AM, Rahmani, S, Ranabhat, CL, Ranasinghe, P, Rao, CR, Rasali, DP, Rashidi, MM, Ratan, ZA, Rawaf, DL, Rawaf, S, Rawal, L, Renzaho, AMN, Rezaei, N, Rezaei, S, Rezaeian, M, Riahi, SM, Rodriguez, ER, Roth, GA, Rwegerera, GM, Saddik, B, Sadeghi, E, Sadeghian, R, Saeed, U, Saeedi, F, Sagar, R, Sahebkar, A, Sahoo, H, Sahraian, MA, Rahman, KSU, Salahi, S, Salimzadeh, H, Samy, AM, Sanmarchi, F, Milicevic, MMS, Sarikhani, Y, Sathian, B, Saya, GK, Sayyah, M, Schmidt, MI, Schutte, AE, Schwarzinger, M, Schwebel, DC, Seidu, AA, Kumar, NS, SeyedAlinaghi, S, Seylani, A, Sha, F, Shahin, S, Sanavi, FS, Shahrokhi, S, Shaikh, MA, Shaker, E, Shakhmardanov, MZ, Beyranvand, MS, Sheikhbahaei, S, Sheikhi, RA, Shetty, A, Shetty, JK, Shiferaw, DS, Shigematsu, M, Shiri, R, Shirkoohi, R, Shivakumar, KM, Shivarov, V, Shobeiri, P, Shrestha, R, Sidemo, NB, Sigfusdottir, ID, Silva, DAS, da Silva, NT, Singh, JA, Singh, S, Skryabin, VY, Skryabina, AA, Sleet, DA, Solmi, M, Solomon, Y, Song, S, Song, Y, Sorensen, RJD, Soshnikov, S, Soyiri, IN, Stein, DJ, Subba, SH, Szocska, M, Seisdedos, RT, Tabuchi, T, Taheri, M, Tan, KK, Tareke, M, Tarkang, EE, Temesgen, G, Temesgen, WA, Temsah, MH, Thankappan, KR, Thapar, R, Thomas, NK, Tiruneh, C, Todorovic, J, Torrado, M, Touvier, M, Palone, MRT, Mai, TNT, Llimos, ST, Tripathy, JP, Vakilian, A, Valizadeh, R, Varmaghani, M, Varthya, SB, Vasankari, TJ, Vos, T, Wagaye, B, Waheed, Y, Walde, MT, Wang, C, Wang, Y, Wang, YP, Westerman, R, Wickramasinghe, ND, Wubetu, AD, Xu, S, Yamagishi, K, Yang, L, Yesera, GEE, Yigit, A, Yigit, V, Yimaw, AE, Yon, DK, Yonemoto, N, Yu, C, Zadey, S, Zahir, M, Zare, I, Zastrozhin, MS, Zastrozhina, A, Zhang, ZJ, Zhong, C, Zmaili, M, Zuniga, YMH, Gakidou, E, and Madureira-Carvalho, AM
- Abstract
BACKGROUND: The health risks associated with moderate alcohol consumption continue to be debated. Small amounts of alcohol might lower the risk of some health outcomes but increase the risk of others, suggesting that the overall risk depends, in part, on background disease rates, which vary by region, age, sex, and year. METHODS: For this analysis, we constructed burden-weighted dose-response relative risk curves across 22 health outcomes to estimate the theoretical minimum risk exposure level (TMREL) and non-drinker equivalence (NDE), the consumption level at which the health risk is equivalent to that of a non-drinker, using disease rates from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2020 for 21 regions, including 204 countries and territories, by 5-year age group, sex, and year for individuals aged 15-95 years and older from 1990 to 2020. Based on the NDE, we quantified the population consuming harmful amounts of alcohol. FINDINGS: The burden-weighted relative risk curves for alcohol use varied by region and age. Among individuals aged 15-39 years in 2020, the TMREL varied between 0 (95% uncertainty interval 0-0) and 0·603 (0·400-1·00) standard drinks per day, and the NDE varied between 0·002 (0-0) and 1·75 (0·698-4·30) standard drinks per day. Among individuals aged 40 years and older, the burden-weighted relative risk curve was J-shaped for all regions, with a 2020 TMREL that ranged from 0·114 (0-0·403) to 1·87 (0·500-3·30) standard drinks per day and an NDE that ranged between 0·193 (0-0·900) and 6·94 (3·40-8·30) standard drinks per day. Among individuals consuming harmful amounts of alcohol in 2020, 59·1% (54·3-65·4) were aged 15-39 years and 76·9% (73·0-81·3) were male. INTERPRETATION: There is strong evidence to support recommendations on alcohol consumption varying by age and location. Stronger interventions, particularly those tailored towards younger individuals, are needed to reduce the substantial global health loss attribu
- Published
- 2022
21. Signs and symptoms of COVID-19 in patients with multiple sclerosis
- Author
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Schiavetti, I., Carmisciano, L., Ponzano, M., Cordioli, C., Cocco, E., Marfia, G. A., Inglese, M., Filippi, M., Radaelli, M., Bergamaschi, R., Immovilli, P., Capobianco, M., De Rossi, N., Brichetto, G., Scandellari, C., Cavalla, P., Pesci, I., Confalonieri, P., Perini, P., Trojano, M., Lanzillo, R., Tedeschi, G., Comi, G., Battaglia, M. A., Patti, F., Salvetti, M., Sormani, M. P., Abbadessa, G., Aguglia, U., Allegorico, L., Rossi Allegri, B. M., Alteno, A., Amato, M. P., Annovazzi, P., Antozzi, C., Appendino, L., Arena, S., Baione, V., Balgera, R., Barcella, V., Baroncini, D., Barrila, C., Bellacosa, A., Bellucci, G., Bergamaschi, V., Bezzini, D., Biolzi, B., Bisecco, A., Bonavita, S., Borriello, G., Bosa, C., Bosco, A., Bovis, F., Bozzali, M., Brambilla, L., Brescia Morra, V., Buccafusca, M., Bucciantini, E., Bucello, S., Buscarinu, M. C., Cabboi, M. P., Calabrese, M., Calabria, F., Caleri, F., Camilli, F., Caniatti, L. M., Cantello, R., Capra, R., Capuano, R., Carta, P., Celani, M. G., Cellerino, M., Cerqua, R., Chisari, C., Clerici, R., Clerico, M., Cola, G., Conte, A., Conti, M. Z., Cordano, C., Cordera, S., Corea, F., Correale, C., Cottone, S., Crescenzo, F., Curti, E., D'Ambrosio, A., D'Amico, E., Danni, M. C., D'Arma, A., Dattola, V., de Biase, S., De Luca, G., De Mercanti, S. F., De Mitri, P., De Stefano, N., Della Cava, F. M., Cava, M. D., Di Lemme, S., di Napoli, M., Di Sapio, A., Docimo, R., Dutto, A., Evangelista, L., Fanara, S., Fantozzi, R., Ferraro, D., Ferro, M. T., Fioretti, C., Fratta, M., Frau, J., Fronza, M., Furlan, R., Gajofatto, A., Gallo, A., Gallo, P., Gasperini, C., Ghazaryan, A., Giometto, B., Gobbin, F., Govone, F., Granella, F., Grange, E., Grasso, M. G., Grimaldi, L. M. E., Guareschi, A., Guaschino, C., Guerrieri, S., Guidetti, D., Juergenson, I. B., Iaffaldano, P., Ianniello, A., Iasevoli, L., Imperiale, D., Infante, M. T., Iodice, R., Iovino, A., Konrad, G., Landi, D., Lapucci, C., Lavorgna, L., L'Episcopo, M. R., Leva, S., Liberatore, G., Lo Re, M., Longoni, M., Lopiano, L., Lorefice, L., Lucchini, Matteo, Lus, G., Maimone, D., Malentacchi, M., Mallucci, G., Malucchi, S., Mancinelli, C. R., Mancinelli, L., Manganotti, P., Maniscalco, G. T., Mantero, V., Marangoni, S., Marastoni, D., Marinelli, F., Marti, A., Boneschi Martinelli, F., Masserano, Z. F., Matta, F., Mendozzi, L., Meucci, G., Miante, S., Miele, G., Milano, E., Mirabella, Massimiliano, Missione, R., Moccia, M., Moiola, L., Montepietra, S., Montibragadin, M., Montini, F., Motta, R., Nardone, R., Gabri Nicoletti, C., Nobile-Orazio, E., Nozzolillo, A., Onofrj, M., Orlandi, R., Palmieri, A., Paolicelli, D., Pasquali, L., Pasto, L., Pedrazzoli, E., Petracca, M., Petrone, A., Piantadosi, C., Pietroboni, A. M., Pinardi, F., Portaccio, E., Pozzato, M., Pozzilli, C., Prosperini, L., Protti, A., Ragonese, P., Rasia, S., Realmuto, S., Repice, A., Rigoni, E., Rilla, M. T., Rinaldi, F., Romano, C. M., Ronzoni, M., Rovaris, M., Ruscica, F., Sabattini, L., Salemi, G., Saraceno, L., Sartori, A., Sbragia, E., Scarano, G. I., Scarano, V., Sessa, M., Sgarito, C., Sibilia, G., Siciliano, G., Signori, A., Signoriello, E., Sinisi, L., Sireci, F., Sola, P., Solaro, C., Sotgiu, S., Sparaco, M., Stromillo, M. L., Strumia, S., Susani, E. L., Tabiadon, G., Teatini, F., Tomassini, V., Tonietti, S., Torri, V., Tortorella, C., Toscano, S., Totaro, R., Trotta, M., Turano, G., Ulivelli, M., Valentino, M., Vaula, G., Vecchio, D., Vercellino, M., Verrengia, E. P., Vianello, M., Virgilio, E., Vitetta, F., Vollaro, S., Zaffaroni, M., Zampolini, M., Zarbo, I. R., Zito, A., Zuliani, L., Lucchini M. (ORCID:0000-0002-0447-2297), Mirabella M. (ORCID:0000-0002-7783-114X), Schiavetti, I., Carmisciano, L., Ponzano, M., Cordioli, C., Cocco, E., Marfia, G. A., Inglese, M., Filippi, M., Radaelli, M., Bergamaschi, R., Immovilli, P., Capobianco, M., De Rossi, N., Brichetto, G., Scandellari, C., Cavalla, P., Pesci, I., Confalonieri, P., Perini, P., Trojano, M., Lanzillo, R., Tedeschi, G., Comi, G., Battaglia, M. A., Patti, F., Salvetti, M., Sormani, M. P., Abbadessa, G., Aguglia, U., Allegorico, L., Rossi Allegri, B. M., Alteno, A., Amato, M. P., Annovazzi, P., Antozzi, C., Appendino, L., Arena, S., Baione, V., Balgera, R., Barcella, V., Baroncini, D., Barrila, C., Bellacosa, A., Bellucci, G., Bergamaschi, V., Bezzini, D., Biolzi, B., Bisecco, A., Bonavita, S., Borriello, G., Bosa, C., Bosco, A., Bovis, F., Bozzali, M., Brambilla, L., Brescia Morra, V., Buccafusca, M., Bucciantini, E., Bucello, S., Buscarinu, M. C., Cabboi, M. P., Calabrese, M., Calabria, F., Caleri, F., Camilli, F., Caniatti, L. M., Cantello, R., Capra, R., Capuano, R., Carta, P., Celani, M. G., Cellerino, M., Cerqua, R., Chisari, C., Clerici, R., Clerico, M., Cola, G., Conte, A., Conti, M. Z., Cordano, C., Cordera, S., Corea, F., Correale, C., Cottone, S., Crescenzo, F., Curti, E., D'Ambrosio, A., D'Amico, E., Danni, M. C., D'Arma, A., Dattola, V., de Biase, S., De Luca, G., De Mercanti, S. F., De Mitri, P., De Stefano, N., Della Cava, F. M., Cava, M. D., Di Lemme, S., di Napoli, M., Di Sapio, A., Docimo, R., Dutto, A., Evangelista, L., Fanara, S., Fantozzi, R., Ferraro, D., Ferro, M. T., Fioretti, C., Fratta, M., Frau, J., Fronza, M., Furlan, R., Gajofatto, A., Gallo, A., Gallo, P., Gasperini, C., Ghazaryan, A., Giometto, B., Gobbin, F., Govone, F., Granella, F., Grange, E., Grasso, M. G., Grimaldi, L. M. E., Guareschi, A., Guaschino, C., Guerrieri, S., Guidetti, D., Juergenson, I. B., Iaffaldano, P., Ianniello, A., Iasevoli, L., Imperiale, D., Infante, M. T., Iodice, R., Iovino, A., Konrad, G., Landi, D., Lapucci, C., Lavorgna, L., L'Episcopo, M. R., Leva, S., Liberatore, G., Lo Re, M., Longoni, M., Lopiano, L., Lorefice, L., Lucchini, Matteo, Lus, G., Maimone, D., Malentacchi, M., Mallucci, G., Malucchi, S., Mancinelli, C. R., Mancinelli, L., Manganotti, P., Maniscalco, G. T., Mantero, V., Marangoni, S., Marastoni, D., Marinelli, F., Marti, A., Boneschi Martinelli, F., Masserano, Z. F., Matta, F., Mendozzi, L., Meucci, G., Miante, S., Miele, G., Milano, E., Mirabella, Massimiliano, Missione, R., Moccia, M., Moiola, L., Montepietra, S., Montibragadin, M., Montini, F., Motta, R., Nardone, R., Gabri Nicoletti, C., Nobile-Orazio, E., Nozzolillo, A., Onofrj, M., Orlandi, R., Palmieri, A., Paolicelli, D., Pasquali, L., Pasto, L., Pedrazzoli, E., Petracca, M., Petrone, A., Piantadosi, C., Pietroboni, A. M., Pinardi, F., Portaccio, E., Pozzato, M., Pozzilli, C., Prosperini, L., Protti, A., Ragonese, P., Rasia, S., Realmuto, S., Repice, A., Rigoni, E., Rilla, M. T., Rinaldi, F., Romano, C. M., Ronzoni, M., Rovaris, M., Ruscica, F., Sabattini, L., Salemi, G., Saraceno, L., Sartori, A., Sbragia, E., Scarano, G. I., Scarano, V., Sessa, M., Sgarito, C., Sibilia, G., Siciliano, G., Signori, A., Signoriello, E., Sinisi, L., Sireci, F., Sola, P., Solaro, C., Sotgiu, S., Sparaco, M., Stromillo, M. L., Strumia, S., Susani, E. L., Tabiadon, G., Teatini, F., Tomassini, V., Tonietti, S., Torri, V., Tortorella, C., Toscano, S., Totaro, R., Trotta, M., Turano, G., Ulivelli, M., Valentino, M., Vaula, G., Vecchio, D., Vercellino, M., Verrengia, E. P., Vianello, M., Virgilio, E., Vitetta, F., Vollaro, S., Zaffaroni, M., Zampolini, M., Zarbo, I. R., Zito, A., Zuliani, L., Lucchini M. (ORCID:0000-0002-0447-2297), and Mirabella M. (ORCID:0000-0002-7783-114X)
- Abstract
Background and purpose Clinical outcomes of multiple sclerosis (MS) patients affected by coronavirus disease 2019 (COVID-19) have been thoroughly investigated, but a further analysis on main signs and symptoms and their risk factors still needs attention. The objective of this study was to group together and describe based on similarity the most common signs and symptoms of COVID-19 in MS patients and identify all factors associated with their manifestation. Method Logistic and linear regression models were run to recognize factors associated with each pooled group of symptoms and their total number. Results From March 2020 to November 2021, data were collected from 1354 MS patients with confirmed infection of COVID-19. Ageusia and anosmia was less frequent in older people (odds ratio [OR] 0.98; p = 0.005) and more in smoker patients (OR 1.39; p = 0.049). Smoke was also associated with an incremental number of symptoms (OR 1.24; p = 0.031), substance abuse (drugs or alcohol), conjunctivitis and rash (OR 5.20; p = 0.042) and the presence of at least one comorbidity with shortness of breath, tachycardia or chest pain (OR 1.24; p = 0.008). Some disease-modifying therapies were associated with greater frequencies of certain COVID-19 symptoms (association between anti-CD20 therapies and increment in the number of concomitant symptoms: OR 1.29; p = 0.05). Differences in frequencies between the three waves were found for flu-like symptoms (G1, p = 0.024), joint or muscle pain (G2, p = 0.013) and ageusia and anosmia (G5, p < 0.001). All cases should be referred to variants up to Delta. Conclusion Several factors along with the choice of specific therapeutic approaches might have a different impact on the occurrence of some COVID-19 symptoms.
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- 2022
22. SARS-CoV-2 serology after COVID-19 in multiple sclerosis: An international cohort study
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Sormani, M. P., Schiavetti, I., Landi, D., Carmisciano, L., De Rossi, N., Cordioli, C., Moiola, L., Radaelli, M., Immovilli, P., Capobianco, M., Brescia Morra, V., Trojano, M., Tedeschi, G., Comi, G., Battaglia, M. A., Patti, F., Fragoso, Y. D., Sen, S., Siva, A., Furlan, R., Salvetti, M., Abbadessa, G., Aguglia, U., Allegorico, L., Allegri, R. B. M., Amato, M. P., Annovazzi, P., Antozzi, C., Appendino, L., Arena, S., Baione, V., Balgera, R., Barcella, V., Baroncini, D., Barrila, C., Bellacosa, A., Bellucci, G., Bergamaschi, R., Bergamaschi, V., Bezzini, D., Biolzi, B., Bisecco, A., Bonavita, S., Borriello, G., Bosa, C., Bosco, A., Bovis, F., Bozzali, M., Brambilla, L., Brescia, M. V., Brichetto, G., Buccafusca, M., Bucciantini, E., Bucello, S., Buscarinu, M. C., Cabboi, M. P., Calabrese, M., Calabria, F., Caleri, F., Camilli, F., Caniatti, L. M., Cantello, R., Capra, R., Capuano, R., Carta, P., Cavalla, P., Celani, M. G., Cellerino, M., Cerqua, R., Chisari, C., Clerici, R., Clerico, M., Cocco, E., Cola, G., Confalonieri, P., Conte, A., Conti, M. Z., Cordano, C., Cordera, S., Corea, F., Correale, C., Cottone, S., Crescenzo, F., Curti, E., D'Ambrosio, A., D'Amico, E., Danni, M. C., D'Arma, A., Dattola, V., de Biase, S., De Luca, G., De Mercanti, S. F., De Mitri, P., De Stefano, N., Della Cava, M., di Napoli, M., Di Sapio, A., Docimo, R., Dutto, A., Evangelista, L., Fanara, S., Ferraro, D., Ferro, M. T., Filippi, M., Fioretti, C., Fratta, M., Frau, J., Fronza, M., Gajofatto, A., Gallo, A., Gallo, P., Gasperini, C., Ghazaryan, A., Giometto, B., Gobbin, F., Govone, F., Granella, F., Grange, E., Grasso, M. G., Guareschi, A., Guaschino, C., Guerrieri, S., Guidetti, D., Iaffaldano, P., Ianniello, A., Iasevoli, L., Imperiale, D., Infante, M. T., Inglese, M., Iodice, R., Iovino, A., Konrad, G., Lanzillo, R., Lapucci, C., Lavorgna, L., L'Episcopo Maria, R., Leva, S., Liberatore, G., Lo Re, M., Longoni, M., Lopiano, L., Lorefice, L., Lucchini, Matteo, Lus, G., Maimone, D., Malentacchi, M., Mallucci, G., Malucchi, S., Mancinelli, C. R., Mancinelli, L., Manganotti, P., Maniscalco, T. G., Mantero, V., Marangoni, S., Marastoni, D., Marfia, A. G., Marinelli, F., Marti, A., Martinelli Boneschi, F., Masserano Zoli, F., Matta, F., Mendozzi, L., Meucci, G., Miante, S., Miele, G., Milano, E., Mirabella, Massimiliano, Missione, R., Moccia, M., Montepietra, S., Monti Bragadin, M., Montini, F., Motta, R., Nardone, R., Nicoletti, C. G., Nobile-Orazio, E., Nozzolillo, A., Onofrj, M., Orlandi, R., Palmieri, A., Paolicelli, D., Pasquali, L., Pasto, L., Pedrazzoli, E., Perini, P., Pesci, I., Petracca, M., Petrone, A., Piantadosi, C., Pietroboni, A. M., Pinardi, F., Ponzano, M., Portaccio, E., Pozzato, M., Pozzilli, C., Prosperini, L., Protti, A., Ragonese, P., Rasia, S., Realmuto, S., Repice, A., Rigoni, E., Rilla, M. T., Rinaldi, F., Romano, C. M., Ronzoni, M., Rovaris, M., Ruscica, F., Sabattini, L., Salemi, G., Saraceno, L., Sartori, A., Sbragia, E., Scandellari, C., Scarano Giuditta, I., Scarano, V., Schillaci, V., Sessa, M., Sgarito, C., Sibilia, G., Siciliano, G., Signori, A., Signoriello, E., Sinisi, L., Sireci, F., Sola, P., Solaro, C., Sotgiu, S., Sparaco, M., Stromillo, M. L., Strumia, S., Susani, L. E., Tabiadon, G., Teatini, F., Tomassini, V., Tonietti, S., Torri, C. V., Tortorella, C., Toscano, S., Totaro, R., Trotta, M., Turano, G., Ulivelli, M., Valentino, M., Vaula, G., Vecchio, D., Vercellino, M., Verrengia, E. P., Vianello, M., Virgilio, E., Vitetta, F., Vollaro, S., Zaffaroni, M., Zampolini, M., Zarbo, I. R., Zito, A., Zuliani, L., Lucchini M. (ORCID:0000-0002-0447-2297), Mirabella M. (ORCID:0000-0002-7783-114X), Sormani, M. P., Schiavetti, I., Landi, D., Carmisciano, L., De Rossi, N., Cordioli, C., Moiola, L., Radaelli, M., Immovilli, P., Capobianco, M., Brescia Morra, V., Trojano, M., Tedeschi, G., Comi, G., Battaglia, M. A., Patti, F., Fragoso, Y. D., Sen, S., Siva, A., Furlan, R., Salvetti, M., Abbadessa, G., Aguglia, U., Allegorico, L., Allegri, R. B. M., Amato, M. P., Annovazzi, P., Antozzi, C., Appendino, L., Arena, S., Baione, V., Balgera, R., Barcella, V., Baroncini, D., Barrila, C., Bellacosa, A., Bellucci, G., Bergamaschi, R., Bergamaschi, V., Bezzini, D., Biolzi, B., Bisecco, A., Bonavita, S., Borriello, G., Bosa, C., Bosco, A., Bovis, F., Bozzali, M., Brambilla, L., Brescia, M. V., Brichetto, G., Buccafusca, M., Bucciantini, E., Bucello, S., Buscarinu, M. C., Cabboi, M. P., Calabrese, M., Calabria, F., Caleri, F., Camilli, F., Caniatti, L. M., Cantello, R., Capra, R., Capuano, R., Carta, P., Cavalla, P., Celani, M. G., Cellerino, M., Cerqua, R., Chisari, C., Clerici, R., Clerico, M., Cocco, E., Cola, G., Confalonieri, P., Conte, A., Conti, M. Z., Cordano, C., Cordera, S., Corea, F., Correale, C., Cottone, S., Crescenzo, F., Curti, E., D'Ambrosio, A., D'Amico, E., Danni, M. C., D'Arma, A., Dattola, V., de Biase, S., De Luca, G., De Mercanti, S. F., De Mitri, P., De Stefano, N., Della Cava, M., di Napoli, M., Di Sapio, A., Docimo, R., Dutto, A., Evangelista, L., Fanara, S., Ferraro, D., Ferro, M. T., Filippi, M., Fioretti, C., Fratta, M., Frau, J., Fronza, M., Gajofatto, A., Gallo, A., Gallo, P., Gasperini, C., Ghazaryan, A., Giometto, B., Gobbin, F., Govone, F., Granella, F., Grange, E., Grasso, M. G., Guareschi, A., Guaschino, C., Guerrieri, S., Guidetti, D., Iaffaldano, P., Ianniello, A., Iasevoli, L., Imperiale, D., Infante, M. T., Inglese, M., Iodice, R., Iovino, A., Konrad, G., Lanzillo, R., Lapucci, C., Lavorgna, L., L'Episcopo Maria, R., Leva, S., Liberatore, G., Lo Re, M., Longoni, M., Lopiano, L., Lorefice, L., Lucchini, Matteo, Lus, G., Maimone, D., Malentacchi, M., Mallucci, G., Malucchi, S., Mancinelli, C. R., Mancinelli, L., Manganotti, P., Maniscalco, T. G., Mantero, V., Marangoni, S., Marastoni, D., Marfia, A. G., Marinelli, F., Marti, A., Martinelli Boneschi, F., Masserano Zoli, F., Matta, F., Mendozzi, L., Meucci, G., Miante, S., Miele, G., Milano, E., Mirabella, Massimiliano, Missione, R., Moccia, M., Montepietra, S., Monti Bragadin, M., Montini, F., Motta, R., Nardone, R., Nicoletti, C. G., Nobile-Orazio, E., Nozzolillo, A., Onofrj, M., Orlandi, R., Palmieri, A., Paolicelli, D., Pasquali, L., Pasto, L., Pedrazzoli, E., Perini, P., Pesci, I., Petracca, M., Petrone, A., Piantadosi, C., Pietroboni, A. M., Pinardi, F., Ponzano, M., Portaccio, E., Pozzato, M., Pozzilli, C., Prosperini, L., Protti, A., Ragonese, P., Rasia, S., Realmuto, S., Repice, A., Rigoni, E., Rilla, M. T., Rinaldi, F., Romano, C. M., Ronzoni, M., Rovaris, M., Ruscica, F., Sabattini, L., Salemi, G., Saraceno, L., Sartori, A., Sbragia, E., Scandellari, C., Scarano Giuditta, I., Scarano, V., Schillaci, V., Sessa, M., Sgarito, C., Sibilia, G., Siciliano, G., Signori, A., Signoriello, E., Sinisi, L., Sireci, F., Sola, P., Solaro, C., Sotgiu, S., Sparaco, M., Stromillo, M. L., Strumia, S., Susani, L. E., Tabiadon, G., Teatini, F., Tomassini, V., Tonietti, S., Torri, C. V., Tortorella, C., Toscano, S., Totaro, R., Trotta, M., Turano, G., Ulivelli, M., Valentino, M., Vaula, G., Vecchio, D., Vercellino, M., Verrengia, E. P., Vianello, M., Virgilio, E., Vitetta, F., Vollaro, S., Zaffaroni, M., Zampolini, M., Zarbo, I. R., Zito, A., Zuliani, L., Lucchini M. (ORCID:0000-0002-0447-2297), and Mirabella M. (ORCID:0000-0002-7783-114X)
- Abstract
Background: The MuSC-19 project is an Italian cohort study open to international partners that collects data on multiple sclerosis (MS) patients with COVID-19. During the second wave of the pandemic, serological tests became routinely available. Objective: To evaluate the seroprevalence of anti-SARS-CoV-2 antibodies according to the use of disease-modifying therapy (DMT) in a subset of patients included in the MuSC-19 data set who had undergone a serological test. Methods: We evaluated the association between positive serological test results and time elapsed since infection onset, age, sex, Expanded Disability Status Scale score, comorbidities and DMT exposure using a multivariable logistic model. Results: Data were collected from 423 patients (345 from Italy, 61 from Turkey and 17 from Brazil) with a serological test performed during follow-up. Overall, 325 out of 423 tested patients (76.8%) had a positive serological test. At multivariate analysis, therapy with anti-CD20 was significantly associated with a reduced probability of developing antibodies after COVID-19 (odds ratio (OR) = 0.20, p = 0.002). Conclusion: Patients with MS maintain the capacity to develop humoral immune response against SARS-COV-2, although to a lesser extent when treated with anti-CD20 drugs. Overall, our results are reassuring with respect to the possibility to achieve sufficient immunization with vaccination.
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- 2022
23. A longitudinal real‐life comparison study of natalizumab and fingolimod
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Lanzillo, R., Carotenuto, A., Moccia, M., Saccà, F., Russo, C. V., Massarelli, M., De Rosa, A., and Brescia Morra, V.
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- 2017
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24. Growth hormone/IGF-1 axis longitudinal evaluation in clinically isolated syndrome patients on interferon β-1b therapy: stimulation tests and correlations with clinical and radiological conversion to multiple sclerosis
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Lanzillo, R., Di Somma, C., Quarantelli, M., Carotenuto, A., Pivonello, C., Moccia, M., Cianflone, A., Marsili, A., Puorro, G., Saccà, F., Russo, C. V., De Luca Picione, C., Ausiello, F., Colao, A., and Morra, Brescia V.
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- 2017
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25. Grey: white matter ratio at diagnosis and the risk of 10‐year multiple sclerosis progression
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Moccia, M., Quarantelli, M., Lanzillo, R., Cocozza, S., Carotenuto, A., Carotenuto, B., Alfano, B., Prinster, A., Triassi, M., Nardone, A., Palladino, R., Brunetti, A., and Brescia Morra, V.
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- 2017
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26. POSA80 Natalizumab Utilization in Terms of Dosing Interval and Costs: A 2015-2019 Population-Based Study
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Affinito, G, primary, Santoni, L, additional, Montella, E, additional, Masera, S, additional, Brescia Morra, V, additional, Triassi, M, additional, Palladino, R, additional, and Moccia, M, additional
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- 2022
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27. Associations between cognitive impairment at onset and disability accrual in young people with multiple sclerosis
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Carotenuto A., Moccia M., Costabile T., Signoriello E., Paolicelli D., Simone M., Lus G., Brescia Morra V., Lanzillo R., Rosa L., Barbarulo A. M., Falco F., Viterbo R. G., Lauro F., Carotenuto, Antonio, Moccia, Marcello, Costabile, Teresa, Signoriello, Elisabetta, Paolicelli, Damiano, Simone, Marta, Lus, Giacomo, Brescia Morra, Vincenzo, Lanzillo, Roberta, Carotenuto, A., Moccia, M., Costabile, T., Signoriello, E., Paolicelli, D., Simone, M., Lus, G., Brescia Morra, V., Lanzillo, R., Rosa, L., Barbarulo, A. M., Falco, F., Viterbo, R. G., and Lauro, F.
- Subjects
Adult ,Male ,medicine.medical_specialty ,Multiple Sclerosis ,020205 medical informatics ,Adolescent ,Population ,lcsh:Medicine ,02 engineering and technology ,Predictive markers ,Risk Assessment ,Article ,03 medical and health sciences ,Disability Evaluation ,Young Adult ,0302 clinical medicine ,Cognition ,Visual memory ,Recurrence ,Internal medicine ,0202 electrical engineering, electronic engineering, information engineering ,medicine ,Humans ,Cognitive Dysfunction ,Longitudinal Studies ,Young adult ,Age of Onset ,10. No inequality ,education ,lcsh:Science ,Child ,Retrospective Studies ,education.field_of_study ,Multidisciplinary ,Proportional hazards model ,business.industry ,Multiple sclerosis ,lcsh:R ,Retrospective cohort study ,Cognitive neuroscience ,medicine.disease ,Disease Progression ,lcsh:Q ,Female ,Age of onset ,business ,030217 neurology & neurosurgery ,Follow-Up Studies - Abstract
Differently from the adult multiple sclerosis (MS) population, the predictive value of cognitive impairment in early-onset MS is still unknown. We aim to evaluate whether cognitive performances at disease onset predict disease progression in young people with MS. This is a retrospective study on early onset (
- Published
- 2019
28. 324 Piloting of a Toolkit for Delirium Detection and Management at Four Emergency Departments
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Lesser, A., primary, Stuck, A., additional, Ring, H., additional, Moccia, M., additional, Bruursema, S., additional, Anderson, R., additional, Babine, R., additional, Davenport, K., additional, Baker, S., additional, and Inouye, S., additional
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- 2021
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29. A multicenter survey on access to care in Multiple Sclerosis-related trigeminal neuralgia
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Ferraro, D., Annovazzi, P., Lanzillo, R., Calabrese, M., Fantozzi, R., De Luca, G., Cordioli, C., Paolicelli, D., Ragonese, P., Gajofatto, A., Lo Fermo, S., Cavalla, P., Tortorella, C., Pesci, I., Gallo, A., Pinardi, F., Di Filippo, M., Maniscalco, G.T., Nociti, V., Radaelli, M., Tomassini, V., Buscarinu, M.C., Moccia, M., Camera, V., Cocco, E., Gasperini, C., and Solaro, C.
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- 2021
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30. The Framingham cardiovascular risk score in multiple sclerosis
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Moccia, M., Lanzillo, R., Palladino, R., Maniscalco, G. T., De Rosa, A., Russo, C., Massarelli, M., Carotenuto, A., Postiglione, E., Caporale, O., Triassi, M., and Morra, Brescia V.
- Published
- 2015
- Full Text
- View/download PDF
31. Increased bilirubin levels in de novo Parkinsonʼs disease
- Author
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Moccia, M., Picillo, M., Erro, R., Longo, K., Amboni, M., Santangelo, G., Palladino, R., Allocca, R., Caporale, O., Triassi, M., Pellecchia, M. T., Barone, P., and Vitale, C.
- Published
- 2015
- Full Text
- View/download PDF
32. Cognitive performances and DAT imaging in early Parkinsonʼs disease with mild cognitive impairment: a preliminary study
- Author
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Pellecchia, M. T., Picillo, M., Santangelo, G., Longo, K., Moccia, M., Erro, R., Amboni, M., Vitale, C., Vicidomini, C., Salvatore, M., Barone, P., and Pappatà, S.
- Published
- 2015
- Full Text
- View/download PDF
33. Uric acid relates to dopamine transporter availability in Parkinsonʼs disease
- Author
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Moccia, M., Pappatà, S., Erro, R., Picillo, M., Vitale, C., Amboni, M., Longo, K., Palladino, R., Barone, P., and Pellecchia, Maria Teresa
- Published
- 2015
- Full Text
- View/download PDF
34. Relationship between apathy and cognitive dysfunctions in de novo untreated Parkinsonʼs disease: a prospective longitudinal study
- Author
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Santangelo, G., Vitale, C., Trojano, L., Picillo, M., Moccia, M., Pisano, G., Pezzella, D., Cuoco, S., Erro, R., Longo, K., Pellecchia, M. T., Amboni, M., De Rosa, A., De Michele, G., and Barone, P.
- Published
- 2015
- Full Text
- View/download PDF
35. Presence and progression of non-motor symptoms in relation to uric acid in de novo Parkinsonʼs disease
- Author
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Moccia, M., Picillo, M., Erro, R., Vitale, C., Longo, K., Amboni, M., Santangelo, G., Palladino, R., Capo, G., Orefice, G., Barone, P., and Pellecchia, M. T.
- Published
- 2015
- Full Text
- View/download PDF
36. Label-free DNA biosensing by topological light confinement
- Author
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Zito, G, Zito, G, Sanità, G, Guilcapi Alulema, B, Lara Yépez, SN, Lanzio, V, Riminucci, F, Cabrini, S, Moccia, M, Avitabile, C, Lamberti, A, Mocella, V, Rendina, I, Romano, S, Zito, G, Zito, G, Sanità, G, Guilcapi Alulema, B, Lara Yépez, SN, Lanzio, V, Riminucci, F, Cabrini, S, Moccia, M, Avitabile, C, Lamberti, A, Mocella, V, Rendina, I, and Romano, S
- Abstract
Large-area and transparent all-dielectric metasurfaces sustaining photonic bound states in the continuum (BICs) provide a set of fundamental advantages for ultrasensitive biosensing. BICs bridge the gap of large effective mode volume with large experimental quality factor. Relying on the transduction mechanism of reactive sensing principle, herein, we first numerically study the potential of subwavelength confinement driven by topological decoupling from free space radiation for BIC-based biosensing. Then, we experimentally combine this capability with minimal and low-cost optical setup, applying the devised quasi-BIC resonator for PNA/DNA selective biosensing with real-time monitoring of the binding event. A sensitivity of 20 molecules per micron squared is achieved, i.e. 0.01 pg. Further enhancement can easily be envisaged, pointing out the possibility of single-molecule regime. This work aims at a precise and ultrasensitive approach for developing low-cost point-of-care tools suitable for routine disease prescreening analyses in laboratory, also adaptable to industrial production control.
- Published
- 2021
37. Non-motor predictors for levodopa requirement in de-novo patients with Parkinsonʼs disease: 1021
- Author
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Erro, R., Picillo, M., Vitale, C., Amboni, M., Moccia, M., Pellecchia, M. T., and Barone, P.
- Published
- 2014
38. Neuropsychological correlates of Pisa syndrome in Parkinsonʼs disease: 998
- Author
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Vitale, C., Falco, F., Allocca, R., Erro, R., Moccia, M., Trojano, L., Barone, P., and Santangelo, G.
- Published
- 2014
39. Relationship between apathy and cognitive dysfunctions in de novo, untreated Parkinsonʼs disease: A prospective longitudinal study: 888
- Author
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Santangelo, G., Vitale, C., Picillo, M., Moccia, M., Pisano, G., Pezzella, D., Cuoco, S., Longo, K., Erro, R., Pellecchia, M. T., Amboni, M., De Rosa, A., De Michele, G., and Barone, P.
- Published
- 2014
40. Serum uric acid relates with non-motor symptoms in de novo Parkinsonʼs disease: 877
- Author
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Moccia, M., Picillo, M., Erro, R., Vitale, C., Longo, K., Amboni, M., Spina, E., Pezzella, D., Santangelo, G., Pellecchia, M. T., and Barone, P.
- Published
- 2014
41. How does smoking affect olfaction in Parkinsonʼs disease?: 376
- Author
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Moccia, M., Picillo, M., Erro, R., Spina, E., Vitale, C., Amboni, M., Falco, F., Santangelo, G., Pellecchia, M. T., and Barone, P.
- Published
- 2014
42. Hypomorphic NOTCH3 allele in an Italian family with CADASIL features: EP1217
- Author
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Moccia, M., Erro, R., Mosca, L., Cervasio, M., Caranci, F., Leonardi, A., Vitale, C., Picillo, M., Allocca, R., Falco, F., Santangelo, G., Del Basso-De Caro, M. L., Penco, S., and Barone, P.
- Published
- 2014
43. Insulin-like growth factor-1 predicts cognitive functions at 2-year follow-up in early, drug-naïve Parkinsonʼs disease
- Author
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Pellecchia, M. T., Santangelo, G., Picillo, M., Pivonello, R., Longo, K., Pivonello, C., Vitale, C., Amboni, M., De Rosa, A., Moccia, M., Erro, R., De Michele, G., Santoro, L., Colao, A., and Barone, P.
- Published
- 2014
- Full Text
- View/download PDF
44. Validation of an Italian version of the 40-item University of Pennsylvania Smell Identification Test that is physician administered: Our experience on one hundred and thirty-eight healthy subjects
- Author
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Picillo, M., Iavarone, A., Pellecchia, M. T., Amboni, M., Erro, R., Moccia, M., Vitale, C., Longo, K., Santangelo, G., Spina, E., Scannapieco, S., Orefice, G., and Barone, P.
- Published
- 2014
- Full Text
- View/download PDF
45. Retinal vascular density in multiple sclerosis: a one year follow up
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Lanzillo, R, Cennamo, G, Moccia, M, Criscuolo, C, Carotenuto, A, Frattaruolo, N, Sparnelli, F, MELENZANE, ANTONIETTA, Lamberti, A, Servillo, G, Tranfa, F, De Crecchio, G, Brescia Morra, V, Lanzillo, R, Cennamo, G, Moccia, M, Criscuolo, C, Carotenuto, A, Frattaruolo, N, Sparnelli, F, Melenzane, Antonietta, Lamberti, A, Servillo, G, Tranfa, F, De Crecchio, G, and Brescia Morra, V
- Subjects
retina ,optical coherence tomography ,parafovea ,multiple sclerosi ,vascular density - Abstract
Vascular pathology is increasingly acknowledged as a risk factor of multiple sclerosis (MS). Vascular density (VD) is reduced in MS patients' eyes on optical coherence tomography (OCT) angiography (A).
- Published
- 2019
46. Risk of invasive fungal infections among patients treated with disease modifying treatments for multiple sclerosis: a comprehensive review
- Author
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Scotto, R., primary, Reia, A., additional, Buonomo, A.R., additional, Moccia, M., additional, Viceconte, G., additional, Pisano, E., additional, Zappulo, E., additional, Brescia Morra, V., additional, and Gentile, I., additional
- Published
- 2021
- Full Text
- View/download PDF
47. Bioisosteric discovery of NPA101.3, a second generation RET/VEGFR2 inhibitor optimized for single-agent polypharmacology
- Author
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Moccia, M., Frett, B., Zhang, L., Lakkaniga, R., Briggs, D.C., Chauhan, R., Brescia, A., Federico, G., Santoro, M., McDonald, Neil Q., Li, H., and Carlomagno, F.
- Subjects
congenital, hereditary, and neonatal diseases and abnormalities ,endocrine system ,endocrine system diseases ,bcs - Abstract
RET receptor tyrosine kinase is a driver oncogene in human cancer. We recently identified the clinical drug candidate Pz-1, which targets RET and VEGFR2. A key in vivo metabolite of Pz-1 is its less active demethylated pyrazole analogue. Using bioisosteric substitution methods, here, we report the identification of NPA101.3, lacking the structural liability for demethylation. NPA101.3 showed selective inhibitory profile and an inhibitory concentration 50 (IC50) of
- Published
- 2020
48. Characteristics and treatment of Multiple Sclerosis-related trigeminal neuralgia: An Italian multi-centre study
- Author
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Ferraro, D., Annovazzi, P., Moccia, M., Lanzillo, R., De Luca, G., Nociti, Viviana, Fantozzi, R., Paolicelli, D., Ragonese, P., Gajofatto, A., Boffa, L., Cavalla, P., Lo Fermo, S., Buscarinu, M. C., Lorefice, L., Cordioli, C., Calabrese, M., Gallo, A., Pinardi, F., Tortorella, C., Di Filippo, M., Camera, V., Maniscalco, G. T., Radaelli, M., Buttari, F., Tomassini, V., Cocco, E., Gasperini, C., Solaro, C., Nociti V. (ORCID:0000-0002-4607-3948), Ferraro, D., Annovazzi, P., Moccia, M., Lanzillo, R., De Luca, G., Nociti, Viviana, Fantozzi, R., Paolicelli, D., Ragonese, P., Gajofatto, A., Boffa, L., Cavalla, P., Lo Fermo, S., Buscarinu, M. C., Lorefice, L., Cordioli, C., Calabrese, M., Gallo, A., Pinardi, F., Tortorella, C., Di Filippo, M., Camera, V., Maniscalco, G. T., Radaelli, M., Buttari, F., Tomassini, V., Cocco, E., Gasperini, C., Solaro, C., and Nociti V. (ORCID:0000-0002-4607-3948)
- Abstract
Background: The prevalence of trigeminal neuralgia (TN) in Multiple Sclerosis (MS) patients is higher than in the general population and its management can be particularly challenging. Our aim is to describe the characteristics, treatment and prognostic factors of MS-related TN in a retrospective multicentre study. Methods: Neurologists members of the RIREMS group (Rising Researchers in MS) enrolled MS patients with a TN diagnosis and filled out a spreadsheet comprising their clinical data. Results: Population consisted of 298 patients. First-choice preventive treatments were carbamazepine and oxcarbazepine. A surgical procedure was performed in 81 (30%) patients, most commonly gamma knife stereotactic radiosurgery (37%), followed by microvascular decompression (22%) and radiofrequency thermocoagulation (21%); one third of patients underwent at least two procedures. Surgery was associated with higher disability, male sex and longer interval between MS and TN onset. Patients (77%) who stayed on at least one preventive medication at most recent follow-up, after a mean period of 8 years, had a higher disability compared to the untreated group. Furthermore, patients with higher disability at TN onset were less likely to discontinue their first preventive medication due to pain remission, had bilateral TN more frequently and underwent surgical interventions earlier. Conclusion: MS patients with a higher disability at TN onset and with a longer interval between MS and TN onset had differing clinical features and outcomes: pain was more frequently bilateral, surgery was more frequent and anticipated, and preventive medication discontinuation due to pain remission was less common.
- Published
- 2020
49. Engineered Acoustic Sensors for Underwater Applications Based on Coated Fiber Bragg Gratings
- Author
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Moccia, M., primary, Pisco, M., additional, Consales, M., additional, Iadicicco, A., additional, Cutolo, A., additional, Galdi, V., additional, and Cusano, A., additional
- Published
- 2013
- Full Text
- View/download PDF
50. PDG80 Healthcare Resource Utilization and Costs for Extended Interval Dosing of Natalizumab in Relapsing Remitting Multiple Sclerosis
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Moccia, M., primary, Loperto, I., additional, Santoni, L., additional, Masera, S., additional, Carotenuto, A., additional, Triassi, M., additional, Brescia Morra, V., additional, and Palladino, R., additional
- Published
- 2020
- Full Text
- View/download PDF
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