321 results on '"Mohammad Ishaq"'
Search Results
2. Sarcoid Uveitis: An Experience from a Tertiary Care Hospital in Pakistan.
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Mohammad Ishaq, Syeda Urooj Riaz, Nousheen Iqbal, Asad Raza Jafri, Urooj Fatima, Amir Hussain, Khizra Ishaq, and Shifa Ishaq
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Sarcoidosis ,Uveitis ,Sun Classification ,Visual Acquity ,Systemic Diseases ,Medicine (General) ,R5-920 ,Dentistry ,RK1-715 - Abstract
Objectives: The Primary objective was to find the frequency of Sarcoid Uveitis among the patients pre- sented with Uveitis.The secondary objective was to follow the patients of sarcoid uveitis over treat- ment.. Methods: We did an observational prospective study, after acquiring ethical review letter from IRB Medicine department outpatient services of Jinnah Medical College Hospital Korangi was used where patients with Uveitis were referred for evaluation of systemic disease during jan 2019 to dec 2020. These patients underwent history, examination and biochemical and radiological investigations and were followed over a period of 1 year to see response to treatment. Results: A total of 372 patients presented with established uveitis out of which 36 patients i.e. 66 eyes presented to our eye clinic with decrease in vision with a mean age of 42±2 years. Among 36 patients, 89% presented with redness of eye and 72% presented with eye pain where as 8 % pre- sented with photophobia and floaters. Biochemically >10mg/dl calcium was observed in 18(50%) pa- tients and ACE level was found to be more than 40nmol/ml/min in 30(83.3%) patients. Among them 32 (88.9%) patients showed resolved inflammation whereas 2(5.56%) showed a change in inflamma- tion and 2(5.56%) showed no change. Conclusion: We found sarcoid uveitis as fairly common cause of uveitis. The patients were treated with the standard treatment of steroids and immunosuppressants i.e. Azathioprine and we concluded that use of steroids and immunosuppressant improved the outcome in our patients. The patients re- sponded fairly well to the designed treatment.
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- 2024
3. South Asian medical cohorts reveal strong founder effects and high rates of homozygosity
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Jeffrey D. Wall, J. Fah Sathirapongsasuti, Ravi Gupta, Asif Rasheed, Radha Venkatesan, Saurabh Belsare, Ramesh Menon, Sameer Phalke, Anuradha Mittal, John Fang, Deepak Tanneeru, Manjari Deshmukh, Akshi Bassi, Jacqueline Robinson, Ruchi Chaudhary, Sakthivel Murugan, Zameer ul-Asar, Imran Saleem, Unzila Ishtiaq, Areej Fatima, Saqib Shafi Sheikh, Shahid Hameed, Mohammad Ishaq, Syed Zahed Rasheed, Fazal-ur-Rehman Memon, Anjum Jalal, Shahid Abbas, Philippe Frossard, Christian Fuchsberger, Lukas Forer, Sebastian Schoenherr, Qixin Bei, Tushar Bhangale, Jennifer Tom, Santosh Gopi Krishna Gadde, Priya B V, Naveen Kumar Naik, Minxian Wang, Pui-Yan Kwok, Amit V. Khera, B. R. Lakshmi, Adam S. Butterworth, Rajiv Chowdhury, John Danesh, Emanuele di Angelantonio, Aliya Naheed, Vinay Goyal, Rukmini M. Kandadai, Hrishikesh Kumar, Rupam Borgohain, Adreesh Mukherjee, Pettarusp M. Wadia, Ravi Yadav, Soaham Desai, Niraj Kumar, Atanu Biswas, Pramod Kumar Pal, Uday B. Muthane, Shymal K. Das, Vedam L. Ramprasad, Prashanth L. Kukkle, Somasekar Seshagiri, Sekar Kathiresan, Arkasubhra Ghosh, V. Mohan, Danish Saleheen, Eric W. Stawiski, and Andrew S. Peterson
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Science - Abstract
Abstract The benefits of large-scale genetic studies for healthcare of the populations studied are well documented, but these genetic studies have traditionally ignored people from some parts of the world, such as South Asia. Here we describe whole genome sequence (WGS) data from 4806 individuals recruited from the healthcare delivery systems of Pakistan, India and Bangladesh, combined with WGS from 927 individuals from isolated South Asian populations. We characterize population structure in South Asia and describe a genotyping array (SARGAM) and imputation reference panel that are optimized for South Asian genomes. We find evidence for high rates of reproductive isolation, endogamy and consanguinity that vary across the subcontinent and that lead to levels of rare homozygotes that reach 100 times that seen in outbred populations. Founder effects increase the power to associate functional variants with disease processes and make South Asia a uniquely powerful place for population-scale genetic studies.
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- 2023
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4. Genome-wide analysis of blood lipid metabolites in over 5000 South Asians reveals biological insights at cardiometabolic disease loci
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Eric L. Harshfield, Eric B. Fauman, David Stacey, Dirk S. Paul, Daniel Ziemek, Rachel M. Y. Ong, John Danesh, Adam S. Butterworth, Asif Rasheed, Taniya Sattar, Zameer-ul-Asar, Imran Saleem, Zoubia Hina, Unzila Ishtiaq, Nadeem Qamar, Nadeem Hayat Mallick, Zia Yaqub, Tahir Saghir, Syed Nadeem Hasan Rizvi, Anis Memon, Mohammad Ishaq, Syed Zahed Rasheed, Fazal-ur-Rehman Memon, Anjum Jalal, Shahid Abbas, Philippe Frossard, Danish Saleheen, Angela M. Wood, Julian L. Griffin, and Albert Koulman
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Lipidomics ,Genetics ,Gaussian Graphical Modelling ,Network analysis ,South Asian ,Medicine - Abstract
Abstract Background Genetic, lifestyle, and environmental factors can lead to perturbations in circulating lipid levels and increase the risk of cardiovascular and metabolic diseases. However, how changes in individual lipid species contribute to disease risk is often unclear. Moreover, little is known about the role of lipids on cardiovascular disease in Pakistan, a population historically underrepresented in cardiovascular studies. Methods We characterised the genetic architecture of the human blood lipidome in 5662 hospital controls from the Pakistan Risk of Myocardial Infarction Study (PROMIS) and 13,814 healthy British blood donors from the INTERVAL study. We applied a candidate causal gene prioritisation tool to link the genetic variants associated with each lipid to the most likely causal genes, and Gaussian Graphical Modelling network analysis to identify and illustrate relationships between lipids and genetic loci. Results We identified 253 genetic associations with 181 lipids measured using direct infusion high-resolution mass spectrometry in PROMIS, and 502 genetic associations with 244 lipids in INTERVAL. Our analyses revealed new biological insights at genetic loci associated with cardiometabolic diseases, including novel lipid associations at the LPL, MBOAT7, LIPC, APOE-C1-C2-C4, SGPP1, and SPTLC3 loci. Conclusions Our findings, generated using a distinctive lipidomics platform in an understudied South Asian population, strengthen and expand the knowledge base of the genetic determinants of lipids and their association with cardiometabolic disease-related loci.
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- 2021
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5. Analyzing human knockouts to validate GPR151 as a therapeutic target for reduction of body mass index.
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Allan Gurtan, John Dominy, Shareef Khalid, Linh Vong, Shari Caplan, Treeve Currie, Sean Richards, Lindsey Lamarche, Daniel Denning, Diana Shpektor, Anastasia Gurinovich, Asif Rasheed, Shahid Hameed, Subhan Saeed, Imran Saleem, Anjum Jalal, Shahid Abbas, Raffat Sultana, Syed Zahed Rasheed, Fazal-Ur-Rehman Memon, Nabi Shah, Mohammad Ishaq, Amit V Khera, John Danesh, Philippe Frossard, and Danish Saleheen
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Genetics ,QH426-470 - Abstract
Novel drug targets for sustained reduction in body mass index (BMI) are needed to curb the epidemic of obesity, which affects 650 million individuals worldwide and is a causal driver of cardiovascular and metabolic disease and mortality. Previous studies reported that the Arg95Ter nonsense variant of GPR151, an orphan G protein-coupled receptor, is associated with reduced BMI and reduced risk of Type 2 Diabetes (T2D). Here, we further investigate GPR151 with the Pakistan Genome Resource (PGR), which is one of the largest exome biobanks of human homozygous loss-of-function carriers (knockouts) in the world. Among PGR participants, we identify eleven GPR151 putative loss-of-function (plof) variants, three of which are present at homozygosity (Arg95Ter, Tyr99Ter, and Phe175LeufsTer7), with a cumulative allele frequency of 2.2%. We confirm these alleles in vitro as loss-of-function. We test if GPR151 plof is associated with BMI, T2D, or other metabolic traits and find that GPR151 deficiency in complete human knockouts is not associated with clinically significant differences in these traits. Relative to Gpr151+/+ mice, Gpr151-/- animals exhibit no difference in body weight on normal chow and higher body weight on a high-fat diet. Together, our findings indicate that GPR151 antagonism is not a compelling therapeutic approach to treatment of obesity.
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- 2022
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6. RNA-activated protein kinase differentially modulates innate immune response mediated by supraphysiological concentrations of thyroid hormone
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Mohammad Ishaq and Ven Natarajan
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Immunologic diseases. Allergy ,RC581-607 - Abstract
Nuclear hormone receptor ligands are known to modulate innate immunity by dampening the immune response induced by pathogens. Here, we report that unlike other ligands, 3,3′,5-triiodo- l -thyronine (T3) induced the type 1 IFN response and expression of IFN-stimulated genes (ISGs). T3 action was found to be significantly amplified at supraphysiological concentrations (SPC) and in combination with double-stranded RNA mimic polyinosinic–polycytidylic acid. Induction by T3 was due to non-genomic mechanisms involving integrin binding, calcium mobilization, and phosphatidyl-inositol 3-kinase–AKT pathways, but was independent of TLR3, RIG-I, and IFN-β1 pathways. Whereas siRNA-induced knockdown of RNA-activated protein kinase (PKR) was found to abrogate the T3-induced expression of select ISGs, expression of other T3-induced ISGs was strongly induced by PKR knockdown, indicating the differential role of PKR in modulating T3 action. Together, we describe a novel role of T3 in modulating the innate immune response and identify the importance of PKR in regulating T3-induced immune activation. These findings have important implications in the basic understanding of the mechanisms of T3 function at SPCs and crosstalk involved in the thyroid hormone function and the innate immune response.
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- 2020
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7. Radiative MHD thin film flow of Williamson fluid over an unsteady permeable stretching sheet
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Zahir Shah, Ebenezer Bonyah, Saeed Islam, Waris Khan, and Mohammad Ishaq
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Applied mathematics ,Computational mathematics ,Science (General) ,Q1-390 ,Social sciences (General) ,H1-99 - Abstract
In this research work we have examined the flow of Williamson liquid film fluid with heat transmission and having the impact of thermal radiation embedded in a permeable medium over a time dependent stretching surface. The fluid flow of liquid films is assumed in two dimensions. By using suitable similarity transformation the governing non-linear partial differential equations have been transformed into non-linear differential equations. An optimal approach has been used to acquire the solution of the modelled problem. The convergence of the technique has been shown numerically. The impact of the Skin friction and Nusslet number and their influence on thin film flow are shown numerically. Thermal radiation, unsteadiness effect and porosity have mainly focused in this paper. Furthermore, for conception and physical demonstration the entrenched parameters, like porosity parameter k, Prandtl number Pr, unsteadiness parameter S, Radiation parameter Rd, Magnetic parameter M, and Williamson fluid parameter have been discussed graphically in detail with their effect on liquid film flow.
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- 2018
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8. Prolonged Impacted Denture in the Esophagus: A Case Report and Review of the Literature
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Gulzar Dar, Farooq Ganie, Mohammad Ishaq, Kowsar Jan, Zargar Ali, Ghulam Lone, Mashkoor Beigh, Tariq Abdullah, Maqsood Dar, and Mir Sidiq
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Artificial denture ,Esophagus ,Rigid esophagoscopy ,Foreign body ingestion ,Medical emergencies. Critical care. Intensive care. First aid ,RC86-88.9 - Abstract
Foreign body ingestion and aspiration is among the most common causes of emergency department visit associated with high morbidity and mortality. Ingested and aspirated denture is rare conditions being scarcely reported in the literature. We herein report a 57-year-old man who presented with 2-day history of liquid and solid dysphagia who was diagnosed to have impacted denture in esophagus since 3 years prior to presentation. He was diagnosed to have esophagus adenocarcinoma and had undergone esophageal radiotherapy. The denture was removed successfully using esophagoscopy and the patient was discharged after 48-hour care with good condition. To prevent accidental ingestion, dentures should be made to fit properly. Damaged or malfitting dentures should be discarded and replaced. Patients should be strongly advised against wearing them during sleep-time.
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- 2015
9. Coal Ash as a Low Cost Adsorbent for the Removal of Xylenol Orange from Aqueous Solution
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Mohammad Ishaq, Khalid Saeed, Imtiaz Ahmad, Sirraj Sultan, and Sohail Akhtar
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xylenol orange ,coal ash ,kinetics ,edx ,Chemical engineering ,TP155-156 ,Chemistry ,QD1-999 - Abstract
The removal ofxylenol orange from aqueous solution onto the coal ash was investigated at room temperature. The results show that the adsorption capacity of xylenol orange increased as the adsorption time increased and then equilibrium established after 30 min adsorption time. The results obtained revealed that the coal ash removed about 80 % of xylenol orange from the aqueous solution within 40 min. The effect of pH also studied, which showed that the adsorption of xylenol orange on the coal ash decreased as pH increased. The equilibrium adsorption isotherm data was fitted in Langmuir and Freundlich model equation and was found that the data followed both Langmuir and Freundlich isotherm models. Furthermore, we used a statistical measure (rank equation) in order to measure the strength of the relationship between the adsorption of xylenol orange onto coal ash and different adsorption time, and adsorption of different concentration of dye at equilibrium time.
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- 2014
10. Contributors
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Acharya, Shamasunder, primary, Arumugam, Somasundaram, additional, Bagchi, Manashi, additional, Bagchi, Debasis, additional, Bala, Sapna, additional, Balakrishnan, Grrishma, additional, Bandopadhyay, Purbita, additional, Bandyopadhyay, Arun, additional, Banerjee, Mainak, additional, Banik, Samudra P., additional, Bhadada, Sanjay Kumar, additional, Bhat, Sowrabha, additional, Bhatnagar, Apoorva, additional, Bhowmik, Eshita, additional, Bir, Aritri, additional, Biswas, Subhash Ch., additional, Brodosi, Lucia, additional, Burrage, Lauren, additional, Buttari, Brigitta, additional, Chakrabarti, Sankha Shubhra, additional, Chakrabarti, Partha, additional, Chakrabarti, Sasanka, additional, Chakraborty, Sanjoy, additional, Chatterjee, Aroup, additional, Chatterjee, Sudip, additional, Chattopadhyay, Dipanjan, additional, Chaudhury, Tirthankar, additional, Cherian, Kripa Elizabeth, additional, Chowdhury, Amarta Shankar, additional, Dabadghao, Preeti, additional, Dabas, Aashima, additional, Das, Snehasis, additional, Das, Pamelika, additional, Das, Jishna, additional, Dasgupta, Riddhi, additional, Dasgupta, I., additional, Dissanayake, H.A., additional, Downs, Bernard W., additional, Dutta, Deep, additional, Duttaroy, Asim K., additional, Fariduddin, Maria M., additional, Fazeli, Mostafa, additional, Ferns, Gordon A., additional, Ferrari, Carlos K.B., additional, Gangopadhyay, Kalyan Kumar, additional, Ganguly, Dipyaman, additional, Ganguly, Anirban, additional, Ganie, Mohd Ashraf, additional, Garg, M.K., additional, Gargari, Piyas, additional, Geer, Mohammad Ishaq, additional, Ghayour-Mobarhan, Majid, additional, Ghosh, Amrit Raj, additional, Ghosh, Arindam, additional, Ghosh, Rituparna, additional, Goswami, Soumik, additional, Grover, B., additional, Gupta, Sudhiranjan, additional, Haldipur, Ashrita C., additional, Hayer, M.K., additional, Heller, Simon, additional, Iqbal, Ahmed, additional, Jacob, Jubbin J., additional, Jebasingh, Felix, additional, Jude, Edward B., additional, Kanumilli, Naresh, additional, Kapoor, Nitin, additional, Kettler, Zelpha K., additional, Khoo, C.M., additional, Krishnaveni, G.V., additional, Kumar, Sandeep, additional, Kumar, Angad, additional, Kushner, Steve, additional, Lee, K.O., additional, Li, Dong, additional, Li, Li, additional, Maisnam, Indira, additional, Majumdar, Sujoy, additional, Majumder, Anirban, additional, Marchesini, Giulio, additional, Marwaha, Raman Kumar, additional, Mirshad, Reshma, additional, Misra, A., additional, Mitra, Sandip Kumar, additional, Mittal, Madhukar, additional, Mohan, Viswanathan, additional, Mondal, Sunetra, additional, Müller, Walter E., additional, Mukherjee, Sutapa, additional, Mukherjee, J.J., additional, Mukhopadhyay, Rajarshi, additional, Mukhopadhyay, Satinath, additional, Muthiah, Mark, additional, Naik, Ramachandra G., additional, Pal, Rimesh, additional, Palui, Rajan, additional, Paul, Thomas V., additional, Petroni, Maria Letizia, additional, Prasanna, Vani Sai, additional, Preuss, Harry G., additional, Profumo, Elisabetta, additional, Puppala, Alekhya, additional, Rankawat, Sourbh, additional, Rasool, Abid, additional, Ray, Aleepta Guha, additional, Ray, Sayantan, additional, Ray, Sandipan, additional, Raychaudhuri, Smriti K., additional, Raychaudhuri, Siba P., additional, Roy, Trina, additional, Saberi-Karimian, Maryam, additional, Safarian-Bana, Hamideh, additional, Saha, Arpita, additional, Saha, Sarmistha, additional, Sahar, Tajali, additional, Sahoo, J.P., additional, Saikia, Uma Kaimal, additional, Sanjeevi, Carani B., additional, Sanyal, Arun J., additional, Sarkar, Jit, additional, Sarkar, Sulogna, additional, Saso, Luciano, additional, Satpathi, Tirthankar, additional, Sharif, Adnan, additional, Shetty, Shrinath Pratap, additional, Singh, Awadhesh Kumar, additional, Singh, Ritu, additional, Sinha, Ashim, additional, Somasundaram, N.P., additional, Sreedhar, Remya, additional, Srividya, N., additional, Tabatabaeizadeh, Seyed-Amir, additional, Tan, Eunice Xiang Xuan, additional, Thomas, Nihal, additional, Unnikrishnan, Ranjit, additional, Velayutham, Ravichandiran, additional, Vella, Adrian, additional, Viswanathan, Vijay, additional, Vora, Jiten, additional, Wagle, S.S., additional, Welch, Andrew, additional, Yajnik, C.S., additional, Yellurkar, Manoj Limbraj, additional, Yousuf, Syed Douhath, additional, and Zhang, Jian, additional
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- 2024
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11. Inter-relationship between polycystic ovary syndrome and metabolic syndrome
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Ganie, Mohd Ashraf, primary, Rasool, Abid, additional, Sahar, Tajali, additional, and Geer, Mohammad Ishaq, additional
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- 2024
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12. Entropy Generation on Nanofluid Thin Film Flow of Eyring–Powell Fluid with Thermal Radiation and MHD Effect on an Unsteady Porous Stretching Sheet
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Mohammad Ishaq, Gohar Ali, Zahir Shah, Saeed Islam, and Sher Muhammad
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entropy generation ,Eyring–Powell fluid ,thin film ,unsteady porous stretching sheet ,nanofluid ,HAM ,thermal radiation ,MHD ,Science ,Astrophysics ,QB460-466 ,Physics ,QC1-999 - Abstract
This research paper investigates entropy generation analysis on two-dimensional nanofluid film flow of Eyring–Powell fluid with heat amd mass transmission over an unsteady porous stretching sheet in the existence of uniform magnetic field (MHD). The flow of liquid films are taken under the impact of thermal radiation. The basic time dependent equations of heat transfer, momentum and mass transfer are modeled and converted to a system of differential equations by employing appropriate similarity transformation with unsteady dimensionless parameters. Entropy analysis is the main focus in this work and the impact of physical parameters on the entropy profile are discussed in detail. The influence of thermophoresis and Brownian motion has been taken in the nanofluids model. An optima approach has been applied to acquire the solution of modeled problem. The convergence of the HAM (Homotopy Analysis Method) has been presented numerically. The disparity of the Nusslet number, Skin friction, Sherwood number and their influence on the velocity, heat and concentration fields has been scrutinized. Moreover, for comprehension, the physical presentation of the embedded parameters are explored analytically for entropy generation and discussed.
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- 2018
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13. Suicidal behavior among teenagers: A review
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Mohammad Ishaq, Muslim Shah, Shaista Taufiq Meghani, and Neelam Punjani
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suicide ,teenagers ,suicidal behavior ,Medicine - Abstract
After every 16 minutes one individual die not merely from a disease or an accident but intentionally through suicide. Literature reveals that it is a long process usually stretches over years from suicidal ideation to planning and finally an attempt. The causes of suicidal behavior are immense which captivate these poor and innocent creatures in great troubles. In teenagers the suicidal ideations are related to multiple internal and external factors. They consume different lethal liquids and adopt different methods for performing this violent act. Further on its impact is not only on her individual and family life but has a great impact on the society as well. It is not an essay task to eradicate this violent act but as we a responsible member of the society we can assess their suffering and agony and help them identifying different social groups. Along with it we can also prevent the suicide at three different levels that’s primary secondary and tertiary. We can also do the counseling. In conclusion, I would say that it is a rising issue of today’s world and we all must give our efforts to show a reduction in its prevalence.
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- 2011
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14. Frequency of modifiable risk factors in stroke patients admitted to teaching hospitals in Bannu district
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Abdul Razzaq, Mian Akhtar Ali Kakakhail, Fawad Ahmad, and Mohammad Ishaq
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Medicine - Abstract
Background: Stroke is one of the common causes of admission in medical and neurological wards in the hospitals. The aim of this study to assess the prevalence of modifiable risks factors in stroke patients admitted to the teaching hospitals in Bannu District. Methods: This descriptive study was conducted on 56 patients admitted with stroke to medical units of District Headquarter and Khalifa Gul Nawaz Teaching Hospitals, Bannu, from January 2011 to December 2011. History and thorough clinical examination were performed on all patients to collect all relevant information. Necessary laboratory investigations were done. CT was performed to establish the diagnosis of stroke. All the findings were recorded on printed proformas. Patients with focal neurological deficit for more than 24 hours, presenting within 7 days of onset, irrespective of age and sex were included in the study. Those with tubercular meningitis, brain tumor, encephalitis, trauma or multiple sclerosis were excluded. Results: Out of 56 patients, 34(60.71%) were males and 22(39.30%) females, with male to female ratio of 1.5:1. Mean age was 57.5 years. Cerebral infarction was found in 37(66%), while hemorrhagic stroke in 19(34%) patients. The risk factors were hypertension in 36(64%),diabetes mellitus14(25%), hyperlipidemia10(18%),and cardiovascular diseases 10(18%). Conclusion: The major modifiable risk factors for stroke in our set-up are hypertension, diabetes mellitus, cardiovascular disease and hyperlipidemia.
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- 2012
15. Diagnostic value of Pleural Biopsy in Exudative Pleural effusion
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Mohammad Ishaq Khattak, Said Amin, Ghulam Shabbier, and Sadiq ur Rehman
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Medicine - Abstract
Background: Exudative pleural effusion is a common diagnostic problem. This study was conducted to find the diagnostic yield of pleural biopsy in exudative pleural effusion. Material & Methods: This descriptive study was conducted in Medical B unit, Khyber Teaching Hospital Peshawar, from January 2009 to December 2009. Cases were confirmed through history, clinical examination and routine investigations. Patients with pleural effusion were first subjected to pleural fluid aspiration. The standard criteria for exudative pleural effusion were used and pleural biopsy was performed in patients with exudative pleural effusion. Specimens were placed in 10% formalin and sent for histopathology. Results: Fifty patients fulfilled the inclusion criteria; 33(66%) male and 17(34%) female. Out of these, 45(90%) had adequate specimen while in 5(10%) the tissue was inadequate. Among the 45 cases with adequate specimen, 40(80%) had a positive yield whereas in 5(10%) the result was nonspecific inflammation. In 40 cases with positive yield, 27(67.5%) were found to be granulomatous inflammation, 10(25%) malignant and 3(7.5%) parapneumonic. The most common complication of pleural biopsy was pain at biopsy site experienced in 100% cases and 3(6%) patients had phenumothrax. Conclusion: Pleural biopsy is safe, minimally invasive procedure and has a high diagnostic yield in exudative pleural effusion.
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- 2012
16. Frequency and risk factors for Hepatitis C among pregnant women
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Tehniyat Ishaq, Mohammad Ishaq Khattak, Said Amin, and Najib ul Haq
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Medicine - Abstract
Background: Hepatitis C virus is a major burden on public health worldwide. This study was conducted to evaluate the frequency and various risk factors for hepatitis C virus among pregnant women in our set-up. Material & Methods: This cross-sectional study was conducted on pregnant women in Gynaecology & Obstetrics Department, Kuwait Teaching Hospital, Peshawar, from January 2007 to January 2009. After detailed history and examination, 5 ml blood was taken. Rapid Immuno-chromatographic Technique for qualitative detection of antibodies for hepatitis C was the screening technique used. Those found positive were confirmed by ELISA. The women were also evaluated for the presence of risk factors for Hepatitis C virus infection. Pre-structured proforma was used to collect and record data. Results were analyzed on SPSS version 16. Results: During the study period 2050 pregnant women were tested for anti-HCV. Out of these, 103(5%) were found positive for anti-HCV. Regarding risk factors; history of previous delivery, abortions, injections, blood transfusion, surgery, dental extraction and tattooing were associated with HCV positive status. Sixty four (62%) anti-HCV positive women did not have any identifiable risk factor. Conclusion: Hepatitis C is a common infection in pregnant women. Risk factors include use of contaminated syringes, contaminated surgical instruments and blood products.
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- 2012
17. Pyrexia of unknown origin: Aetiologic Frequency in a Tertiary Care Hospital
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Mohammad Ishaq Khattak, Tehniyat Ishaq, Said Amin, Sadiq ur Rehman, and Ghulam Shabbir
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Medicine - Abstract
Background: The aetiology of fever varies with age, sex, and geographical location. The most common causes fall in three main groups namely infections, collagen vascular diseases and malignancies. This study was conducted to know the frequency of different diseases causing pyrexia of unknown origin in patients admitted to a tertiary care hospital. Material & Methods: This was a descriptive study of 100 patients with fever admitted to Medical Unit, Khyber Teaching Hospital Peshawar from March 2008 to March 2009. A detailed history and clinical examination was performed on admission and then periodically during the patient stay in the hospital. Based on the history and clinical examination, investigation plan was made. The preliminary laboratory investigations e.g. complete blood count, urinalysis, blood film examination and x-ray chest, were carried out. In every patient an attempt was made to isolate a causative micro-organism through cultures. Results: Out of 100 patients 40 were males and 60 females. We were successful only in 83% of the cases to determine the cause. Majority (57%) had infective aetiology of which tuberculosis was at the top of the list (32%). The other diagnoses included neoplasms (10%), collagen vascular diseases (12%) and miscellaneous (3%). Conclusion: Pyrexia of unknown origin is predominantly caused by infections led by tuberculosis and followed by typhoid fever, malaria and infective endocarditis. Collagen vascular diseases and neoplasms are next to infection. A significant number remains undiagnosed.
- Published
- 2010
18. Factors associated with adherence to anti-hypertensive treatment in Pakistan.
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Saman K Hashmi, Maria B Afridi, Kanza Abbas, Rubina A Sajwani, Danish Saleheen, Philippe M Frossard, Mohammad Ishaq, Aisha Ambreen, and Usman Ahmad
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Medicine ,Science - Abstract
OBJECTIVES: Poor adherence is one of the biggest obstacles in therapeutic control of high blood pressure. The objectives of this study were (i) to measure adherence to antihypertensive therapy in a representative sample of the hypertensive Pakistani population and (ii) to investigate the factors associated with adherence in the studied population. METHODS AND RESULTS: A cross-sectional study was conducted on a simple random sample of 460 patients at the Aga Khan University Hospital (AKUH) and National Institute of Cardiovascular Diseases, Karachi, from September 2005-May 2006. Adherence was assessed using the Morisky Medication Adherence Scale (MMAS), with scores ranging from 0 (non-adherent) to 4 (adherent). In addition to MMAS, patient self-reports about the number of pills taken over a prescribed period were used to estimate adherence as a percentage. AKU Anxiety and Depression Scale (AKU-ADS) was incorporated to find any association between depression and adherence. At a cut-off value of 80%, 77% of the cases were adherent. Upon univariate analyses, increasing age, better awareness and increasing number of pills prescribed significantly improved adherence, while depression showed no association. Significant associations, upon multivariate analyses, included number of drugs that a patient was taking (P
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- 2007
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19. Communicating for the Safe Use of Medicines: Progress and Directions for the 2020s Promoted by the Special Interest Group of the International Society of Pharmacovigilance
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Bahri, Priya, Bowring, Geoffrey, Edwards, Brian D., Anton, Christopher, Aronson, Jeffrey K., Caro-Rojas, Angela, Hugman, Bruce P. J., Mol, Peter G., Trifirò, Gianluca, Ilic, Katarina, Daghfous, Riadh, Fermont, Irene, Furlan, Giovanni, Gaissmaier, Wolfgang, Geer, Mohammad Ishaq, Hartigan-Go, Kenneth Y., Houÿez, François, Neth, Hansjörg, Norgela, Gediminas, Oppamayun, Yaowares, Raynor, D. K. Theo, Bouhlel, Mehdi, Santoro, Federica, and Sultana, Janet
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- 2023
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20. Monitoring and evaluating progress towards universal health coverage: An analysis of health service coverage indicators in Jammu and Kashmir
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Rasool, Shafiqa, primary and Geer, Mohammad Ishaq, additional
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- 2024
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21. Digitization of Manuscripts and Rare Documents in Select Institutions Located in Srinagar, Jammu and Kashmir: a status report.
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Mohammad Ishaq Lone, A. Wahid, and A. Shakoor
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- 2022
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22. Connecting Pharmacists and Other Health Care Providers (HCPs) towards Drug Therapy Optimization: A Pharmaceutical Care Approach
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Mir Javid Iqbal, Geer Mohammad Ishaq, and Abdullah A. Assiri
- Subjects
Medicine - Abstract
Background. Pharmaceutical care services offered by pharmacists rationalize drug therapy, improve patient quality of life, and save patients’ lives. This study was designed to optimize patient drug therapy through pharmaceutical care services offered by a pharmacist in consultation with other health care providers (HCPs) at a tertiary care hospital. Methods. This descriptive study was conducted to assess the role and effectiveness of pharmacists in optimizing drug therapy outcomes. The study was carried out at an internal and pulmonary medicine unit of a tertiary care hospital in Srinagar, Jammu and Kashmir, India, with a total of 50 health care providers (HCPs) (24 doctors, 16 nurses, and 10 pharmacists). A total of 182 patients (males and females) of all age groups were recruited into the study over a period of nine months. Patient-specific pharmaceutical care plans initiated by the pharmacist based on drug therapy-related needs and problems were used to address and optimize drug therapy outcomes in consultation with other HCPs. Results. A total of 388 drug-related problems (DRPs) with an average of 2.29 DRPs per patient were identified, for which 258 pharmaceutical care plans as interventions were proposed, out of which 233 (90.31%) were accepted and implemented. Preassessment and postassessment by HCPs on services rendered by the pharmacist showed a positive change in attitude among HCPs with respect to their endorsement and acceptance of the pharmacist’s services in providing direct patient care. Conclusions. Pharmaceutical care services offered by pharmacists helped in optimizing drug therapy and patient care.
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- 2023
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23. Preservation of rare documentary sources in private libraries and religious institutions
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Lone, Mohammad Ishaq, Wahid, Abdul, and Shakoor, Abdul
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- 2021
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24. The Effect of Climate And Environment on Human Mental State and Health
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Mazloum Yar, Fayaz Gul, primary and Shaheedzooy, Mohammad Ishaq, additional
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- 2024
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25. The Role of Environmental and Geographical Factors in the Education Process.
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Yar, Fayaz Gul Mazloum and Shaheedzooy, Mohammad Ishaq
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GEOGRAPHY education ,LEARNING ability ,SOCIAL development ,CHILD behavior ,CLASSROOM environment - Abstract
In the course of human history, continuous learning has been a vital component of societal development, underscoring the crucial role of a standardized educational environment. The academic setting significantly molds students' learning experiences, necessitating a profound comprehension by teaching staff of environmental factors influencing this process. This article aims to investigate the impact of environmental and geographical factors on the educational process, exploring how these elements shape educational environments and conditions. The research employs a comprehensive approach, delving into the diverse characteristics of environmental elements and their role in creating meaning within learning spaces. The study also analyzes key factors such as classroom size and lighting, recognized for their critical impact on optimizing learning environments. Findings offer valuable insights into the influence of environmental and geographical factors on education, unveiling crucial contributing elements to the creation of optimal educational spaces. The study's outcomes provide a foundation for improving educational structures and enhancing learning experiences by emphasizing the need for tailored learning environments aligned with children's behavioral patterns. [ABSTRACT FROM AUTHOR]
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- 2024
- Full Text
- View/download PDF
26. Chapter 40 - Inter-relationship between polycystic ovary syndrome and metabolic syndrome
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Ganie, Mohd Ashraf, Rasool, Abid, Sahar, Tajali, and Geer, Mohammad Ishaq
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- 2024
- Full Text
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27. Early Complications of Modified Tension-Band Wiring (MTBW) in the Treatment of Close Patellar Fractures
- Author
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Ghareeb Ullah, Mohammad Ishaq, Muhammad Hanif, Kamran Saeed, Usman Ullah, and Jamshed Khan
- Abstract
Introduction: Patella fracture account for 1 Percent of all skeletal fracture, Patella fractures are problematic because the loss of the extensor mechanism of the knee, loss of articular congruity and stiffness of the knee joint. The surgical goals are anatomic reconstruction of the articular surface and stable fixation to allow early motion. Modified tension band wiring MTBW (MTBW) is the procedure of choice for patellar fracture these days because of the dramatic decrease in post-operative complications with this procedure.The complications noted in the early post-operative period are infection,loss of reduction, prominence of hardware, and knee stiffness. Objective: To determine the frequency of early post-operative complications following modified tension band wiring MTBW for closed patellar fractures. Methods: This study was conducted in the department of orthopedic surgery, Lady Reading Hospital, Peshawar from June 2010-september 2011. Through a descriptive cross sectional study, a total of hundred patients of closed patellar fractures were selected in a consecutive manner from the OPD and ER department. All patients were subjected to modified tension band wiring MTBW under G/A by an expert orthopedic surgeon and data was also collected at 1st week, 1st month, 3 months and 6 months regarding early post-operative complications like loss of reduction, infection, prominence of hardware and stiffness. Results: Total patients were hundred. There were 60 (60 Percent) males and 40 (40 Percent) were females. Mean age of the patients was 43.82 years + 14.3SD years (range 20-85 years). 74 (74 Percent) were presented with history of road traffic accident. Overall complication rate by the end of 6 months was a total of 25 Percent with of 21 Percent patients with infection, 11 Percent had developed stiffness, 6 Percent with hardware prominence and only 4 Percent with loss of reduction. Conclusion: The frequency of early post-operative complication following modified tension band wiring MTBW for closed patellar fractures was higher than previously reported and further research work should be carried out to identify the factors responsible for it. Keywords: Developed Stiffness, Closed Fracture Patella, Modified Tension Band Wiring MTBW, Early Post-Operative Complications, Hardware Prominence
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- 2022
28. Frequency of Anterior Knee Pain (AKP) in Different Gender Groups after Total Knee Replacement (TKR)
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Sajawal Khan, Muhammad Hanif, Mohammad Ishaq, Usman Ullah, Ghareeb Ullah, and Jamshed Khan
- Abstract
Introduction: Anterior Knee Pain (AKP) is one of the most common causes of persistent problems after knee replacement. Total Knee Arthroplasty (TKA) is a surgical procedure in which artificial joint or prosthesis replace the damage knee. A significant proportion of the patients experience AKP after surgery. Objective: To find out the frequency of Anterior Knee Pain after Total Knee Arthroplasty. Study Setting: Department of Orthopedics, KTH Khyber Teaching Hospital, Peshawar. Study Design: A Cross sectional study. Study Duration: June -2020 to February -2021. Subjects and Methods: After recording complete history, physical examination and routine baseline investigations were done. Patients were put on OT list and surgeries were performed in all patients by expert orthopedic surgeon designated for performing total knee arthroplasty. Post-operatively, patients were kept under observations for 5 days in ward and were discharged if indicated. Patients were followed at regular intervals and finally at the end of 3rd month to measure the intensity of pain on VAS. Results: Out of 205 patients, 69.3% were males and 30.7% were females. Means ± SD calculated for age was 48.62±7.98 years, for BMI was 24.63±3.07 and for Pain on VAS was 1.31±1.39. Most patients (51.7%) were recorded in 51-60 years age group. Rheumatoid Arthritis (RA) in 18% while Osteoarthritis (OA) was found in 82% patients. 21.5% patients were diabetic while 31.7% patients were hypertensive. AKP at 3rd month was found in 8.8% patients. Conclusion: It is evident that anterior knee pain (AKP) after the total knee arthroplasty (TKA), or total knee replacement (TKR) is prevalent and clinically relevant. There is an absolute need for further investigations to find out ways to decrease or eliminate the AKP after TKA in order to improve the quality of life after this surgery. Keywords: Anterior Knee Pain, Total Knee Replacement, Total Knee Arthroplasty.
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- 2023
29. Clinical Features and Surgical Management of Intracranial Meningioma’s in the Elderly
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Naeem Ul Haq, Hayat Mohammad Khan, Musawer Khan, Mohammad Ishaq, Muhammad Usman, and Gohar Ali
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General Medicine - Abstract
Objective: Given the threat related with surgical intervention of intracranial meningiomas in the older population because of maturing physiology and numerous co morbidities, an endeavor was made to distinguish mediators impacting results and to characterize a category of individuals who ought not be surgically treated because of deprived prognosis. Study Setting: The study was conducted in neurosurgery unit mardan medical complex / bacha khan medical college Name of Hospital, Pakistan. Methods: The investigation of 58 individuals over the age of 70 years was conducted to determine short- and long-term results. Additionally, we derived scores for our patients using the previously reported CRGS, SKALE, and GSS grading systems. Result: As per the SKALE reviewing framework, neurological grimness was exclusively associated with a crucial site (P=0.02). Six people (10.3 percent) capitulated to their wounds. The Karnofsky score (KPS 60 versus KPS 70; P=0.0162), the American Society scale status (ASA 1 or 2 versus ASA 3; P=0.0022), and the evaluation of meningioma’s were totally connected with mortality (P=0.012). The WHO grade (P=0.00048) and Simpson evaluation of resection (P=0.0437) were related with tumor repetition in six cases. Except for patients who died because of medical procedure or reoccurrence (15.5%), majority of subjects improved (50%) or remain unaltered (25.9%) in contrast with their karnofsky score before surgery. Conclusion: Neurological impairment following surgery was only observed in patients with a significant tumor placement (skull base, eloquent area, large vessels indulgence by the tumor). Because of the greatly increased threat of fatality, surgery should be carefully considered in individuals with a low functional state (KPS 60) or a bad bodily state (ASA 3 status). During routine visits, the majority of patients’ neurological health enhanced or remains constant in comparison to their condition before operation.
- Published
- 2022
30. Research Output during the Period of Conflict: A Study
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Lone, Mohammad Ishaq
- Published
- 2017
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31. Open Access Journal Publishing: A DOAJ Perspective with Reference to Environmental Sciences
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Lone, Mohammad Ishaq and Khan, Nusrat Jabeen
- Published
- 2016
32. Connecting Pharmacists and Other Health Care Providers (HCPs) towards Drug Therapy Optimization: A Pharmaceutical Care Approach
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Iqbal, Mir Javid, primary, Mohammad Ishaq, Geer, additional, and Assiri, Abdullah A., additional
- Published
- 2023
- Full Text
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33. Application of Strontium Aluminate Europium and Dysprosium Doped in Cement Mortar as a Luminescent Material for the Maintenance of Green Environments
- Author
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Muhammad Naeem, Saileen Khan, Ivar Zekker, Fazle Subhan, Muhammad Salman, null Alamgir, Asmat Ullah, Saleem Ullah, Ali Hussain, Abbas Khan, Mohammad Ishaq Ali Shah, Muhammad Ikram, Muhammad Zahoor, Luqman Ali Shah, Roy Hendroko Setyobudi, Mohamad Nor Azra, and Asif Khan
- Subjects
Environmental Engineering ,General Chemical Engineering ,Environmental Chemistry ,Geotechnical Engineering and Engineering Geology ,Waste Management and Disposal ,Water Science and Technology - Published
- 2023
34. Communicating for the Safe Use of Medicines : Progress and Directions for the 2020s Promoted by the Special Interest Group of the International Society of Pharmacovigilance
- Author
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Priya Bahri, Geoffrey Bowring, Brian D. Edwards, Christopher Anton, Jeffrey K. Aronson, Angela Caro-Rojas, Bruce P. J. Hugman, Peter G. Mol, Gianluca Trifirò, Katarina Ilic, Riadh Daghfous, Irene Fermont, Giovanni Furlan, Wolfgang Gaissmaier, Mohammad Ishaq Geer, Kenneth Y. Hartigan-Go, François Houÿez, Hansjörg Neth, Gediminas Norgela, Yaowares Oppamayun, D. K. Theo Raynor, Mehdi Bouhlel, Federica Santoro, and Janet Sultana
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Pharmacology ,ddc:150 ,Pharmacology (medical) ,Toxicology - Abstract
published
- Published
- 2023
35. Jämförelse av mattor för vibrationsmatare med hjälp av försöksplanering
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Johannesson, Simon and Mohammad Ishaq, Shukrullah
- Subjects
Optimal design ,DoE ,responsyta ,Mechanical Engineering ,vibrationsmatare ,Försöksplanering ,Statistisk försöksplanering ,vibratory feeders ,Maskinteknik ,Design of experiments ,Design-Expert ,response surface - Abstract
Detab is a company in Jönköping that develops systems for feeding parts for robots and packaging processes. To control the flow of parts on their vibratory feeders, Detab uses different carpets with angled straws. The two mainly used carpets have been discontinued and must now be replaced. A newly emerged option is a contender in replacing one of the carpets. The new white carpet is completely additively manufactured. To compare the old carpet and the new carpet, data is needed to show how different settings affect the flow of the parts. Through design of experiments and response surface methods, tests can be performed in a systematic and mathematical way compare the performance of different settings. Some basic parameters were defined to begin the investigation of which design of experiments method would be used to best compare the carpets. The parameters defined where the parts that would be used in the tests, the factors that were to be adjusted during the tests, the maximum and minimum values of the selected factors and how the results would be measured. Different methods were tested, and finally optimal design was chosen and executed using the program Design-Expert. The completed tests resulted in response surfaces that were constructed using Design-Expert. These response surfaces were analyzed and several similarities and differences between the different carpets were observed. Primarily, it was found that the green carpet had more settings that resulted in a flow above 0 parts/minute. Using Design-Expert, the response surfaces could be analyzed to find the optimal settings and their expected response. These points and more were then compared with tests performed afterwards to see if the expected values matched reality. It turned out that there were some uncertainties in how well the surfaces could predict the response in comparison with reality. Based on the experiments carried out, recommendations were made on how the company should proceed to be able to assess whether the new carpet is worth using in future construction of their machines.
- Published
- 2023
36. COVID-19 LOCKDOWNS AND TOBACCO USE AMONG PRIVATE UNIVERSITY STUDENTS IN DHAKA, BANGLADESH
- Author
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Mohammad Ishaq, Md. Ekhtekharul Islam, Hazur Rahman, and Zahirul Islam
- Abstract
The current study was aimed to investigate the changes in tobacco usage and their correlations among students from a private university in Dhaka, Bangladesh, during the lockdown periods due to the COVID19 pandemic. It is designed as a cross-sectional study in which 572 students participated, among which 207 were smokers, in a self-administered online survey on Google Classrooms through Google forms. The socioeconomic characteristics of the participants, COVID-19, and tobacco use-related information were collected using a close-ended questionnaire. Participating students were asked if their tobacco consumption had changed during the COVID-19 lockdowns compared to before the pandemic. Among the smokers, 31.9% stated an increase in tobacco use in the extended lockdown periods imposed by the authorities to contain coronavirus infection and the rest had no change in such behavior. Tobacco intake in the form of cigarette smoking was substantially increased among the participants who thought the lockdown period was more stressful than preCOVID times (aOR = 5.767, 95% CI: 2.5-13.26, p < 0.001), participants whose caffeine intake increased (aOR = 3.524, 95% CI: 1.70-7.29, p < 0.002), participants who attended any social events during lockdowns (aOR = 2.720, 95% CI: 1.26-5.86, p p
- Published
- 2022
37. The changing political trends in erstwhile FATA: a study of the last three elections
- Author
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Mohammad Ishaq, Muhammad Shoaib, and Raja Qaiser Ahmed
- Subjects
Politics ,Sociology and Political Science ,Political science ,Political economy ,Political Science and International Relations ,FATA - Abstract
This study investigates the changing political trends in erstwhile Federally Administered Tribal Areas of Pakistan. Analysis of the last three elections (2008, 2013, 2018) shows a substantial change in the region. The tribal structure, local traditions, power arrangement and electoral practices have changed significantly over a decade. The extension of the Political Parties Order to the region and its merger with Khyber Pakhtunkhwa stimulated political activities in the area that increased the political awareness of tribal people. The results of the 2013 and 2018 elections highlight the changes. Electoral activities, women participation and voter turnout increased with every election. Tribal youth joined existing political forums to demand their democratic rights. A significant percentage of the young, educated Pashtuns joined the Pashtun Tahafuz Movement in its demand for improved governance.
- Published
- 2021
38. Evolution of My Identity Vis-à-Vis Islam and Kashmir
- Author
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Khan, Mohammad Ishaq and Khan, Nyla Ali, editor
- Published
- 2012
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39. Thermal Radiation and Magnetohydrodynamics Effect on Unsteady Squeezing Non-Newtonian Nanofluids with Heat and Mass Transfer
- Author
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Ubaid Ullah, Shahaz Ahmad Khan, Hamid Khan, Syeda Nazia Jamal, Sher Muhammad, Tahir Khan, Syed Inayat Ali Shah, Syed Asif Hussain, Mohammad Ishaq, and Adnan Khan
- Subjects
Physics::Fluid Dynamics ,Fluid Flow and Transfer Processes ,Nanofluid ,Materials science ,Thermal radiation ,Mechanical Engineering ,Mass transfer ,Mechanics ,Magnetohydrodynamics ,Non-Newtonian fluid - Abstract
The research article primarily deals with non-Newtonian squeezing nanofluid flow between parallel plates by taking into account different phenomena in the modeled problem. The thermal radiation and magneto hydrodynamics impact in fluid flow model is mainly focused in this analysis. The proposed nanofluid model also encompasses thermophoresis and the Brownian movement effects. The basic equations of nanofluids model such as velocity, heat and concentration equations are transformed into ordinary differential equations with the help of appropriate similarity transformations. As a tool, the semi numerical scheme is used for solving the proposed problem with the greatest possible accuracy for the purpose of illustration and analysis. The basic physical parameters involved in velocity, heat and concentration profiles in the nanofluids flow are discussed in detail. The variation of skin friction, Nusselt number and Sherwood number along with their impacts on the velocity, heat and concentration are determined. It is also focused to show the influence of different physical parameters graphically as well as in tabulated form. Excellent agreement between the results of semi analytical method and already published work is obtained, indicating the validity of the semi analytical approach. The study presented herein fills the gap in the literature, and will have a broad impact in industrial and biomedical fields.
- Published
- 2021
40. Supra-subduction zone tectonic setting of the Muslim Bagh Ophiolite, northwestern Pakistan: Insights from geochemistry and petrology
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Kakar, Mohammad Ishaq, Kerr, Andrew C., Mahmood, Khalid, Collins, Alan S., Khan, Mehrab, and McDonald, Iain
- Published
- 2014
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41. Digital Library of Kashmiri Willow Wicker Items: A Small Step towards Preservation of Culture.
- Author
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Mohammad Ishaq Lone and Zahid Ashraf Wani
- Published
- 2014
- Full Text
- View/download PDF
42. Posterior Short Segment Fixation with Index Level Screw for the Unstable Thoracolumbar Burst Fracture
- Author
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Mohammad Masud Rana, Nokul Kumar Datta, Mohammad Ishaq Bhuiyan, Md. Asadullah Ripon, and Dr. Sayed Didarul Islam
- Subjects
General Medicine - Abstract
Background: Thoracolumbar fracture is nearly 90% of all the spine injuries which treated by spine surgeons. The choice of the stabilization type is still the subject of controversy. In long segment fixation, the problem is that more motion segment loss is concerned. The number of motion segments involved in fusion of spine fracture is minimized by posterior short segment fixation with index level screw. Objective: The purpose of the study is to assess the ability of short segment fixation with index level screw at fracture level to correct deformity, maintain correction and prevent failure. Method: 15 patients who were operated between March 2018 and January 2021 were taken for the retrospective analysis. All patients were surgically treated with short segment fixation using a posterior surgical approach with transpedicular instrumentation. Pedicle screws were placed at one level above and below the fracture site. Additionally, pedicle screws were also inserted at the index level of the fracture. All the patients were followed up at 3 months, 6 months and 12 months postoperatively. Results: The Mean pre-operative kyphosis was 14° (range 6° to 24°). Average post-operative kyphosis was 0° (range 6° to −18°). Average follow-up kyphosis of all cases was 10° (range 0.85° to 35.00°). Excluding failures, average follow-up kyphosis was 8° (range 0.85° to 25.00°). The height of the vertebral body was maintained upto 95% in 6 patients, 80% in 6 patients, and 70% in 3 patients. At initial one-month follow-up, average Oswestry disability score was severe at 52.63% (range 16% to 84%). At most recent follow-up, average Oswestry disability score was minimal at 5.5% (range 0% to 16%). One patient was lost to long-term follow- up. Mean difference from one-month follow-up to most recent follow-up (excluding failures) was 47.27% (P < 0.0001). Conclusion: The short same-segment fixation reduces the implantation failure rate and reoperation rate in our study. Long-term correction of kyp
- Published
- 2021
43. Outcome of Varus Derotation Osteotomy for Containment of Femoral Head in Advanced Perthes Disease
- Author
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Mohammad Masud Rana, Mohammad Ishaq Bhuiyan, Abu Zihad Mohammad Salim, Nokul Kumar Datta, and Asadullah Ripon
- Subjects
medicine.medical_specialty ,Femoral head ,medicine.anatomical_structure ,business.industry ,medicine.medical_treatment ,Medicine ,business ,Osteotomy ,Surgery - Abstract
Background: Legg-Calve-Perthes (LCP) disease, or idiopathic avascular necrosis of the femoral head occurs during early childhood and is caused by impaired circulation in the femoral head. Varus derotation osteotomy (VDO) was described over half a century ago, and is now a popular method for the operative treatment of Perthes disease. Objective: To find out the clinical and radiological outcome of varus derotation osteotomy for containment of femoral head in advanced Perthes disease. Materials and Methods: This observational study was conducted in the Department of Orthopaedic Surgery, Bangabandhu Sheikh Mujib Medical University (BSMMU), Shahbag, Dhaka from March 2015 to September 2017. Total 20 cases of advanced Perthes disease were enrolled. Pre- and post-operative period were evaluated by interview and clinical examination by using a semi-structured questionnaire. Demographic and clinical information were recorded. All patients had a pre- and post-operative x-rays. We used visual analog scales (VAS) for scoring pain; Wiberg’s central edge angle, epiphyseal extraction index, neck shaft angle and Larson (Iowa) hip score were used to assess the outcome of VDO. Comparison of continuous variables between the two groups was made with Student’s t-tests. Comparison of proportions between Herring groups B and C were made with chi-square tests. p
- Published
- 2021
44. Preservation of rare documentary sources in private libraries and religious institutions
- Author
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Mohammad Ishaq Lone, Abdul Wahid, and Abdul Shakoor
- Subjects
History ,05 social sciences ,Library science ,Collection management ,0509 other social sciences ,Library and Information Sciences ,050905 science studies ,050904 information & library sciences ,Document storage ,Materials management ,Library materials - Abstract
Purpose The study is an endeavour to find out the preservation status of rare documents in Srinagar. The rare documents, here, mean the manuscripts and rare books, journals, reports, magazines, archival documents, etc. These resources are available in private libraries of individuals and religious institutions in Srinagar. This study aims to find these private libraries of individuals/families and religious institutions, which are unknown to the scholarly world and observe the preservation status of rare documents. The main focus is to document their present preservation status to give an opportunity to the stakeholders, particularly the government organizations, to take appropriate action before they are lost forever. Design/methodology/approach Before conducting the survey, the investigator interviewed 114 persons including literary persons, faith leaders, librarians, faculty members from various prominent institutions in Srinagar to get leads regarding the persons/families and religious institutions in possession of rare documents. The investigator gathered data through two different schedules and later analyzed the same in this study after carrying out a pilot study to make necessary changes to the schedules compiled for the study. The investigator visited personally each family/individual and religious institution to gather the data for months together. Findings An arduous job was carried out in which around 111 individuals/families and religious institutions were found to be having such rare resources. However, the data gathered reveals a dismal picture of private libraries and religious institutions, in possession of rare documents, as almost all caretakers/ families are devoid of any knowledge regarding the maintenance of these important sources of knowledge. Further, the traditional methods of preservation are still in vogue in some private libraries. These traditional methods have opened new areas of research while at the same time can prove detrimental to the collection if they are useless. Originality/value The study is the first of its kind in the summer capital of Jammu and Kashmir i.e. Srinagar. The study gives an idea of preservation status of manuscripts and rare documents including books, magazines, journals, archival documents, etc. so that the same are taken care of for posterity. The study is an eye-opener for the policymakers, conservators, archivists and others interested in historical documents. The study will help in furthering the research process as it needs to be ascertained whether the traditional methods of preservation are fruitful. In short, the study is quite helpful in understanding the nature of collection in Srinagar so that appropriate steps are taken by all particularly the Government in J&K. The paper will surely help in the policy formulation in the future.
- Published
- 2021
45. Dosage and clinical outcomes of medical emergency team and conventional referral mediated unplanned intensive care admissions.
- Author
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Satyavolu, Rajkumar, Ruknuddeen, Mohammad Ishaq, Soar, Natalie, and Edwards, Suzanne Melissa
- Published
- 2023
- Full Text
- View/download PDF
46. A Prospective Observational Study on Prevalence and Prognostic Indicators among Tuberculosis and Multidrug Resistance Tuberculosis Patients in Tertiary Care Teaching Hospital
- Author
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L. Siva Sankar Reddy, A. Noorjahan, K. Mallikarjuna, B. Bhargavi, R. E. Ugandar, and B. Mohammad Ishaq
- Subjects
medicine.medical_specialty ,Tuberculosis ,business.industry ,Disease ,medicine.disease ,Regimen ,Interim ,Internal medicine ,medicine ,Observational study ,Infectious disease (athletes) ,Rural area ,business ,Prospective cohort study - Abstract
Tuberculosis (TB) is a communicable systemic infectious disease with high morbidity and mortality associated with it. Resistance to medications used to treat tuberculosis has been on the rise in recent years. (multidrug-resistant tuberculosis) (MDR-TB) is a significant challenge to (TB) control around the world. An observational research was conducted in a tertiary care teaching hospital to determine the interim pharmacological and microbial results of Rifampicin resistance TB patients. Data from Santhiram Medical College and General Hospital, Nandyal, Kurnool Dist. Andhra Pradesh were obtained from Aug 2020 to Feb 2021, after receiving ethical approval from the Institutional Ethics Committee. The effects of the regimen are determined in terms of cure, finished treatment, treatment failure, number of patients moved to MDR-TB, number of patients who died in long-term MDR-TB regimen patients. Microsoft Excel 2007 was used to analyse the data. There were 82 male and 23 female out of 105 patients included in the study. Of these 75 patients were from rural areas and 40 from urban areas Using the Chi-square test and X2=12.1026, p=0.0005, which was important, the correlation between geographical spread and treatment result was determined. Out of 115 patients, 99 (86.09 percent) were cured of their disease, 06 (5.22 percent) died, 10 (8.69 percent) developed MDR-TB, and 2 (1.74 percent) were deemed medication errors. Males between the ages of 51 and 70 are more vulnerable to TB than females, according to our results. Compared to females of the same age, male patients over 40 years of age are more vulnerable to MDRTB. this was not part of the research objectives, emphasis should not be placed on this as either conclusion or recommendation.
- Published
- 2021
47. S-53-6: ANALYSIS OF BP SCREENING IN PAKISTAN (MMM EXPERIENCE)
- Author
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Mohammad Ishaq
- Subjects
Physiology ,Internal Medicine ,Cardiology and Cardiovascular Medicine - Published
- 2023
48. Cybercrime in India: A study, 2007 to 2011
- Author
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Lone, Mohammad Ishaq
- Published
- 2013
49. Dosage and clinical outcomes of medical emergency team and conventional referral mediated unplanned intensive care admissions
- Author
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Rajkumar Satyavolu, Mohammad Ishaq Ruknuddeen, Natalie Soar, and Suzanne Melissa Edwards
- Subjects
Original Articles ,Critical Care and Intensive Care Medicine ,Critical Care Nursing - Abstract
Background: Unplanned intensive care unit (ICU) admission occurs via activation of medical emergency team (MET) and conventional ICU referral (CIR), i.e., ICU consultation. We aimed to compare the dosage, association with unplanned ICU admissions and hospital mortality between MET and CIR systems. Methods: We performed a retrospective, single centre observational study on unplanned ICU admissions from hospital wards between July 2017 and June 2018. We evaluated the dosage (expressed per 1000 admissions) and association of CIR and MET system with unplanned ICU admission using Chi-square test. The relationship (unadjusted and adjusted to Australia and New Zealand risk of death (ANZROD) and lead time) between unplanned ICU admission pathway (MET vs CIR) and hospital mortality was tested by binary logistic regression analysis [Odds ratio (OR) with 95% confidence interval (CI)]. Results: Out of 38,628 patients hospitalised, 679 had unplanned ICU admission (2%) with an ICU admission rate of 18 per 1000 ward admissions. There were 2153 MET and 453 CIR activations, producing a dosage of 56 and 12 per 1000 admissions, respectively. Higher unplanned ICU admission was significantly associated with CIR compared to MET activation (324/453 (71.5%) vs 355/2153 (16.5%) p < 0.001). On binary logistic regression, MET system was significantly associated with higher hospital mortality on unadjusted analysis (OR 1.65 (95% CI: 1.09–2.48) p = 0.02) but not after adjustment with ANZROD and lead time (OR 1.15 (95% CI: 0.71–1.86), p = 0.58). Conclusions: Compared to CIR, MET system had higher dosage but lower frequency of unplanned ICU admissions and lacked independent association with hospital mortality.
- Published
- 2022
50. Teknoøkonomisk vurdering av grønn hydrogenproduksjon i Norge ved bruk av mikronett i kombinasjon med vindkraft
- Author
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Omar, Mohammad Ishaq and Frausig, Jesper
- Abstract
Store deler av Norges hydrogenforbruk kommer fra grått hydrogen, som har store direkte utslipp. Derfor ønskes det å se på muligheter for alternative kilder for hydrogen i Norge. Et alternativ er grønt hydrogen, som er produsert ved å spalte vann ved bruk av elektrolyse. Norge har høy andel fornybare energikilder i strømnettet, som er optimalt for produksjon av grønt hydrogen ved å konvertere elektrisitet fra strømnettet til grønt hydrogen. Det finnes videre en del vindparker i Norge, blant dem en vindpark på Bessakerfjellet som har en installert effekt på 57,5MW. Anlegget konverterer per i dag vindkraft til elektrisitet, og selger elektrisiteten, ved hjelp av blant annet spottpriser. Spottprisene varierer basert på forbruk og belastning av strømnettet. Gjennom oppgaven blir det sett på samspillsøkonomien mellom å benytte seg av vindkraft i kombinasjon med hydrogenproduksjonsanlegg, hydrogenlagringstank og batteri i et mikronett, med formål om å optimalisere det økonomiske resultatet. Oppgaven benytter spottpriser for år 2019 som et utgangspunkt for teknoøkonomiske analyser, ved gjennomgang av datasettet for spottpriser 2019, finner man spottpris varierer fra 57 kr per MWh til 1069 kr per MWh. Ved å kombinere vindparken på Bessakerfjellet i et mikronett, kan optimaliseringen av strømforbruket oppnås ved hjelp av styringssystem som tar beslutning om hva og hvor strømmen skal gå for å optimalisere det økonomiske resultatet. Gjennom scenarioanalyser gjort i oppgaven, fremkommer det at ulike konfigurasjoner gir ulikt økonomisk bidrag til totaløkonomien, og ulike hovedelementer har ulikt økonomisk bidrag. Av scenarioanalyser gjort i oppgaven vil det være lønnsomt å produsere grønt hydrogen i kombinasjon med vindkraft hvis salgsprisen på hydrogen er over 4,5USD per kg. Bidrag fra batteri er negativt økonomisk og vil derfor fra anbefales å ikke benytte i stor skala hvis formålet er økonomisk optimalisering. Large parts of Norway's hydrogen consumption come from gray hydrogen, which has large direct emissions. Therefore, it is desired to look at opportunities for alternative sources of hydrogen in Norway. An alternative is green hydrogen, which is produced by splitting water using electrolysis. Norway has a high proportion of renewable energy sources in the electricity grid, which is optimal to produce green hydrogen by converting electricity from the electricity grid to green hydrogen. There are also several wind farms in Norway, among them a wind farm on Bessakerfjellet, which has an installed capacity of 57.5 MW. As of today, the plant converts wind power into electricity, and sells the electricity, using spot prices. Spot prices vary based on consumption and load on the power grid. The thesis looks at the interplay economy between using wind power in combination with a hydrogen production plant, hydrogen storage tank and battery in a microgrid, with the aim of optimizing the economic result. The thesis uses spot prices for the year 2019 as a starting point for techno-economic analyzes, when reviewing the data set for spot prices 2019, one finds spot prices vary from NOK 57 per MWh to NOK 1069 per MWh. By combining the wind farm on Bessakerfjellet in a microgrid, the optimization of power consumption can be achieved with the help of a control system that decides what and where the power should go to optimize the financial result. Through scenario analyzes done in the thesis, it emerges that different configurations make different financial contributions to the total economy, and different main elements have different financial contributions. From scenario analyzes done in the thesis, it will be profitable to produce green hydrogen in combination with wind power if the selling price of hydrogen is minimum 4.5USD per kg. Contributions from batteries are negative financially and will therefore be recommended not to use on a large scale if the purpose is economic optimization. M-IØ
- Published
- 2022
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