1. Ancient cattle genomics, origins, and rapid turnover in the Fertile Crescent
- Author
-
Andrew J. Hare, David Orton, Jörg Linstädter, Okan Ertugrul, Abdesalam Mikdad, Pierpaolo Maisano Delser, Johanna Lhuillier, Eberhard Sauer, Adamantios Sampson, Jelena Bulatović, Marjan Mashkour, Victoria E. Mullin, Marta Pereira Verdugo, Benjamin S. Arbuckle, Hossein Davoudi, Ron Kehati, Norbert Benecke, Mikhail V. Sablin, David E. MacHugh, Joachim Burger, Robin Bendrey, S. M. Farhad Vahidi, Kevin G. Daly, Matthew J. Collins, Matthew D. Teasdale, Saeed Ebrahimi, Liora Kolska Horwitz, Daniel G. Bradley, Roya Khazaeli, Fatemeh Azadeh Mohaseb, Chaido Koukouli-Chrysanthaki, George Kazantzis, Claude Rapin, Paula Wapnish Hesse, Amelie Scheu, Ivana Stojanović, Valeria Mattiangeli, Lionel Gourichon, Mutalib Khasanov, Deirdre Fulton, Ioannis Kontopoulos, Tarbiat Modares University [Tehran], ARCHEORIENT - Environnements et sociétés de l'Orient ancien (Archéorient), Université Lumière - Lyon 2 (UL2)-Centre National de la Recherche Scientifique (CNRS), University of Tehran, Zoological Institute, Russian Academy of Sciences [Moscow] (RAS), University of Reading (UOR), Centre d'Études Préhistoire, Antiquité, Moyen-Age (CEPAM), Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Centre National de la Recherche Scientifique (CNRS), Department of Anthropology, Baylor University, Baylor University, Archéozoologie, archéobotanique : sociétés, pratiques et environnements (AASPE), Muséum national d'Histoire naturelle (MNHN)-Centre National de la Recherche Scientifique (CNRS), HEC Paris - Recherche - Hors Laboratoire, Ecole des Hautes Etudes Commerciales (HEC Paris), Verdugo, Marta Pereira [0000-0003-1573-2493], Mullin, Victoria E [0000-0002-2604-2976], Scheu, Amelie [0000-0001-9455-0772], Daly, Kevin G [0000-0002-5579-6144], Maisano Delser, Pierpaolo [0000-0002-1844-1715], Hare, Andrew J [0000-0001-8595-6965], Burger, Joachim [0000-0001-9972-1868], Collins, Matthew J [0000-0003-4226-5501], Fulton, Deirdre [0000-0002-5922-5461], Mohaseb, Fatemeh A [0000-0003-3130-6603], Davoudi, Hossein [0000-0002-5236-1444], Ebrahimi, Saeed [0000-0003-4994-5892], MacHugh, David E [0000-0002-8112-4704], Ertuğrul, Okan [0000-0002-2949-1558], Kontopoulos, Ioannis [0000-0001-5591-8917], Sablin, Mikhail [0000-0002-2773-7454], Bendrey, Robin [0000-0001-5286-1601], Gourichon, Lionel [0000-0002-5160-5902], Arbuckle, Benjamin S [0000-0002-5445-5516], Mashkour, Marjan [0000-0003-3630-9459], Orton, David [0000-0003-4069-8004], Teasdale, Matthew D [0000-0002-7376-9975], Bradley, Daniel G [0000-0001-7335-7092], and Apollo - University of Cambridge Repository
- Subjects
0301 basic medicine ,010506 paleontology ,Mitochondrial DNA ,[SHS.ARCHEO]Humanities and Social Sciences/Archaeology and Prehistory ,Human Migration ,Introgression ,Zoology ,Genomics ,01 natural sciences ,DNA, Mitochondrial ,[SHS]Humanities and Social Sciences ,Domestication ,Evolution, Molecular ,03 medical and health sciences ,Bronze Age ,Animals ,[SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biochemistry [q-bio.BM] ,0105 earth and related environmental sciences ,[SDV.EE]Life Sciences [q-bio]/Ecology, environment ,[SDV.GEN]Life Sciences [q-bio]/Genetics ,Multidisciplinary ,Genome ,biology ,Human migration ,business.industry ,Aurochs ,Zebu ,biology.organism_classification ,humanities ,030104 developmental biology ,Fertility ,Cattle ,business - Abstract
Cattle were domesticated ∼10,000 years ago, but analysis of modern breeds has not elucidated their origins. Verdugo et al. performed genome-wide analysis of 67 ancient Near Eastern Bos taurus DNA samples. Several populations of ancient aurochs were progenitors of domestic cows. These genetic lineages mixed ∼4000 years ago in a region around the Indus Valley. Interestingly, mitochondrial analysis indicated that genetic material likely derived from arid-adapted Bos indicus (zebu) bulls was introduced by introgression.Science, this issue p. 173Genome-wide analysis of 67 ancient Near Eastern cattle, Bos taurus, remains reveals regional variation that has since been obscured by admixture in modern populations. Comparisons of genomes of early domestic cattle to their aurochs progenitors identify diverse origins with separate introgressions of wild stock. A later region-wide Bronze Age shift indicates rapid and widespread introgression of zebu, Bos indicus, from the Indus Valley. This process was likely stimulated at the onset of the current geological age, ~4.2 thousand years ago, by a widespread multicentury drought. In contrast to genome-wide admixture, mitochondrial DNA stasis supports that this introgression was male-driven, suggesting that selection of arid-adapted zebu bulls enhanced herd survival. This human-mediated migration of zebu-derived genetics has continued through millennia, altering tropical herding on each continent.
- Published
- 2019