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1. Searching for star-planet interactions in GJ 486 at radio wavelengths with the uGMRT

Author

Peña-Moñino, L., Pérez-Torres, M., Kansabanik, D., Blázquez-Calero, G., Kavanagh, R. D., Gómez, J. F., Moldón, J., Alberdi, A., Amado, P. J., Anglada, G., Caballero, J. A., Mohan, A., Leto, P., Narang, M., Osorio, M., Revilla, D., and Trigilio, C.

Subjects
Astrophysics - Earth and Planetary Astrophysics, Astrophysics - Solar and Stellar Astrophysics
Abstract

We search for radio emission from star-planet interactions in the M-dwarf system GJ~486, which hosts an Earth-like planet. We observed the GJ~486 system with the upgraded Giant Metrewave Radio Telescope (uGMRT) from 550 to 750 MHz in nine different epochs, between October 2021 and February 2022, covering almost all orbital phases of GJ~486 b from different orbital cycles. We obtained radio images and dynamic spectra of the total and circularly polarized intensity for each individual epoch We do not detect any quiescent radio emission in any epoch above 3$\sigma$. Similarly, we do not detect any bursty emission in our dynamic spectra. While we cannot completely rule out that the absence of a radio detection is due to time variability of the radio emission, or to the maximum electron-cyclotron maser emission being below our observing range, this seems unlikely. We discuss two possible scenarios: an intrinsic dim radio signal, or alternatively, that the anisotropic beamed emission pointed away from the observer. If the non-detection of radio emission from star-planet interaction in GJ~486 is due to an intrinsically dim signal, this implies that, independently of whether the planet is magnetized or not, the mass-loss rate is small (\dot{M}_\star $\lesssim$ 0.3 \dot{M}_\sun) and that, concomitantly, the efficiency of the conversion of Poynting flux into radio emission must be low ($\beta \lesssim 10^{-3}$). Free-free absorption effects are negligible, given the high value of the coronal temperature. Finally, if the anisotropic beaming pointed away from us, this would imply that GJ~486 has very low values of its magnetic obliquity and inclination.

Published
2024

2. TOI-4438 b: a transiting mini-Neptune amenable to atmospheric characterization

Author

Goffo, E., Chaturvedi, P., Murgas, F., Morello, G., Orell-Miquel, J., Acuña, L., Peña-Moñino, L., Pallé, E., Hatzes, A. P., Geraldía-González, S., Pozuelos, F. J., Lanza, A. F., Gandolfi, D., Caballero, J. A., Schlecker, M., Pérez-Torres, M., Lodieu, N., Schweitzer, A., Hellier, C., Jeffers, S. V., Duque-Arribas, C., Cifuentes, C., Béjar, V. J. S., Daspute, M., Dubois, F., Dufoer, S., Esparza-Borges, E., Fukui, A., Hayashi, Y., Herrero, E., Mori, M., Narita, N., Parviainen, H., Tal-Or, L., Vanaverbeke, S., Hermelo, I., Amado, P. J., Dreizler, S., Henning, Th., Lillo-Box, J., Luque, R., Mallorquín, M., Nagel, E., Quirrenbach, A., Reffert, S., Reiners, A., Ribas, I., Schöfer, P., Tabernero, H. M., and Zechmeister, M.

Subjects
Astrophysics - Earth and Planetary Astrophysics
Abstract

We report the confirmation and mass determination of a mini-Neptune transiting the M3.5 V star TOI-4438 (G 182-34) every 7.44 days. A transit signal was detected with NASA's TESS space mission in the sectors 40, 52, and 53. In order to validate the planet TOI-4438 b and to determine the system properties, we combined TESS data with high-precision radial velocity measurements from the CARMENES spectrograph, spanning almost one year, and ground-based transit photometry. We found that TOI-4438 b has a radius of Rb = 2.52 +/- 0.13 R_Earth (5% precision), which together with a mass of Mb=5.4 +/- 1.1 M_Earth (20% precision), results in a bulk density of rho = 1.85+0.51-0.44 g cm-3 (28% precision), aligning the discovery with a volatile-rich planet. Our interior structure retrieval with a pure water envelope yields a minimum water mass fraction of 46% (1-sigma). TOI-4438 b is a volatile-rich mini-Neptune with likely H/He mixed with molecules, such as water, CO_2, and CH_4. The primary star has a J-band magnitude of 9.7, and the planet has a high transmission spectroscopy metric (TSM) of 136 +/- 13. Taking into account the relatively warm equilibrium temperature of T_eq = 435 +/- 15 K, and the low activity level of its host star, TOI-4438 b is one of the most promising mini-Neptunes around an M dwarf for transmission spectroscopy studies., Comment: Accepted for publication on Astronomy & Astrophysics

Published
2024
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3. Wolf 327b: A new member of the pack of ultra-short-period super-Earths around M dwarfs

Author

Murgas, F., Pallé, E., Orell-Miquel, J., Carleo, I., Peña-Moñino, L., Pérez-Torres, M., Watkins, C. N., Jeffers, S. V., Azzaro, M., Barkaoui, K., Belinski, A. A., Caballero, J. A., Charbonneau, D., Cheryasov, D. V., Ciardi, D. R., Collins, K. A., Cortés-Contreras, M., de Leon, J., Duque-Arribas, C., Enoc, G., Esparza-Borges, E., Fukui, A., Geraldía-González, S., Gilbert, E. A., Hatzes, A. P., Hayashi, Y., Henning, Th., Herrero, E., Jenkins, J. M., Lillo-Box, J., Lodieu, N., Lund, M. B., Luque, R., Montes, D., Nagel, E., Narita, N., Parviainen, H., Polanski, A. S., Reffert, S., Schlecker, M., Schöfer, P., Schwarz, R. P., Schweitzer, A., Seager, S., Stassun, K. G., Tabernero, H. M., Terada, Y., Twicken, J. D., Vanaverbeke, S., Winn, J. N., Zambelli, R., Amado, P. J., Quirrenbach, A., Reiners, A., and Ribas, I.

Subjects
Astrophysics - Earth and Planetary Astrophysics, Astrophysics - Solar and Stellar Astrophysics
Abstract

Planets with orbital periods shorter than 1 day are rare and have formation histories that are not completely understood. Small ($R_\mathrm{p} < 2\; R_\oplus$) ultra-short-period (USP) planets are highly irradiated, probably have rocky compositions with high bulk densities, and are often found in multi-planet systems. Additionally, USP planets found around small stars are excellent candidates for characterization using present-day instrumentation. Of the current full sample of approximately 5500 confirmed exoplanets, only 130 are USP planets and around 40 have mass and radius measurements. Wolf 327 (TOI-5747) is an M dwarf ($R_\star = 0.406 \pm 0.015 \; R_\odot$, $M_\star = 0.405 \pm 0.019 \; M_\odot$, $T_{\mathrm{eff}}=3542 \pm 70$ K, and $V = 13$ mag) located at a distance $d = 28.5$ pc. NASA's planet hunter satellite, TESS, detected transits in this star with a period of 0.573 d (13.7 h) and with a transit depth of 818 ppm. Ground-based follow-up photometry, high resolution imaging, and radial velocity (RV) measurements taken with the CARMENES spectrograph confirm the presence of this new USP planet. Wolf 327b is a super-Earth with a radius of $R_\mathrm{p} = 1.24 \pm 0.06 \; R_\oplus$ and a mass of $M_\mathrm{p} = 2.53 \pm 0.46 \; M_\oplus$, yielding a bulk density of $7.24 \pm 1.66 $\,g cm$^{-3}$ and thus suggesting a rocky composition. Owing to its close proximity to its host star ($a = 0.01$ au), Wolf 327b has an equilibrium temperature of $996 \pm 22$ K. This planet has a mass and radius similar to K2-229b, a planet with an inferred Mercury-like internal composition. Planet interior models suggest that Wolf 327b has a large iron core, a small rocky mantle, and a negligible (if any) H/He atmosphere., Comment: 26 pages, 19 figures. Accepted for publication in A&A

Published
2024

4. Evidence for a radiation belt around a brown dwarf

Author

Climent, J. B., Guirado, J. C., Pérez-Torres, M., Marcaide, J. M., and Peña-Moñino, L.

Subjects
Astrophysics - Solar and Stellar Astrophysics, Astrophysics - Earth and Planetary Astrophysics
Abstract

Radio observations of ultracool dwarfs, objects comprising brown dwarfs and the very lowest mass stars, have mainly focused on analyzing their light-curve and spectral energy distributions providing valuable insights into their magnetic fields. However, spatially-resolved studies of such magnetospheres have been elusive so far. Radio interferometric observations of the brown dwarf LSR J1835+3259 reveal an extended magnetosphere with a morphology compatible with the presence of a radiation belt, similar to that of Jupiter and Earth, consisting of energetic particles confined via magnetic mirroring. Our finding suggests that radio emitting ultracool dwarfs may behave as scaled up versions of Jupiter, validating the connection between dipole-ordered magnetic fields and the presence of belt-like morphologies and aurorae beyond our Solar System.

Published
2023
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5. The CARMENES search for exoplanets around M dwarfs. A long-period planet around GJ 1151 measured with CARMENES and HARPS-N data

Author

Blanco-Pozo, J., Perger, M., Damasso, M., Escudé, G. Anglada, Ribas, I., Baroch, D., Caballero, J. A., Cifuentes, C., Jeffers, S. V., Lafarga, M., Kaminski, A., Kaur, S., Nagel, E., Perdelwitz, V., Pérez-Torres, M., Sozzetti, A., Viganò, D., Amado, P. J., Andreuzzi, G., Brown, E. L., Del Sordo, F., Dreizler, S., Galadí-Enríquez, D., Hatzes, A. P., Kürster, M., Lanza, A. F., Melis, A., Molinari, E., Montes, D., Murgia, M., Pallé, E., Peña-Moñino, L., Perrodin, D., Pilia, M., Poretti, E., Quirrenbach, A., Reiners, A., Schweitzer, A., Osorio, M. R. Zapatero, and Zechmeister, M.

Subjects
Astrophysics - Earth and Planetary Astrophysics
Abstract

Detecting a planetary companion in a short-period orbit through radio emission from the interaction with its host star is a new prospect in exoplanet science. Recently, a tantalising signal was found close to the low-mass stellar system GJ 1151 using LOFAR observations. We studied spectroscopic time-series data of GJ 1151 in order to search for planetary companions, investigate possible signatures of stellar magnetic activity, and to find possible explanations for the radio signal. We used the combined radial velocities measured from spectra acquired with the CARMENES, HARPS-N, and HPF instruments, extracted activity indices from those spectra in order to mitigate the impact of stellar magnetic activity on the data, and performed a detailed analysis of Gaia astrometry and all available photometric time series coming from the MEarth and ASAS-SN surveys. We found a M$>$10.6 M$_{\oplus}$ companion to GJ 1151 in a 390d orbit at a separation of 0.57 au. Evidence for a second modulation is also present; this could be due to long-term magnetic variability or a second (substellar) companion. The star shows episodes of elevated magnetic activity, one of which could be linked to the observed LOFAR radio emission. We show that it is highly unlikely that the detected GJ 1151 b, or any additional outer companion is the source of the detected signal. We cannot firmly rule out the suggested explanation of an undetected short-period planet that could be related to the radio emission, as we establish an upper limit of 1.2 M$_{\oplus}$ for the minimum mass., Comment: 18 pages, 11 figures. Accepted version, A&A (2023)

Published
2023
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6. The HD 260655 system: Two rocky worlds transiting a bright M dwarf at 10 pc

Author

Luque, R., Fulton, B. J., Kunimoto, M., Amado, P. J., Gorrini, P., Dreizler, S., Hellier, C., Henry, G. W., Molaverdikhani, K., Morello, G., Peña-Moñino, L., Pérez-Torres, M., Pozuelos, F. J., Shan, Y., Anglada-Escudé, G., Béjar, V. J. S., Bergond, G., Boyle, A. W., Caballero, J. A., Charbonneau, D., Ciardi, D. R., Dufoer, S., Espinoza, N., Everett, M., Fischer, D., Hatzes, A. P., Henning, Th., Hesse, K., Howard, A., Howell, S. B., Isaacson, H., Jeffers, S. V., Jenkins, J. M., Kane, S. R., Kemmer, J., Khalafinejad, S., Kidwell Jr., R. C., Kossakowski, D., Latham, D. W., Lillo-Box, J., Lissauer, J. J., Montes, D., Orell-Miquel, J., Pallé, E., Pollacco, D., Quirrenbach, A., Reffert, S., Reiners, A., Ribas, I., Ricker, G. R., Rogers, L. A., Sanz-Forcada, J., Schlecker, M., Schweitzer, A., Seager, S., Shporer, A., Stassun, K. G., Stock, S., Tal-Or, L., Ting, E. B., Trifonov, T., Vanaverbeke, S., Vanderspek, R., Villaseñor, J., Winn, J. N., Winters, J. G., and Osorio, M. R. Zapatero

Subjects
Astrophysics - Earth and Planetary Astrophysics, Physics - Space Physics
Abstract

We report the discovery of a multi-planetary system transiting the M0 V dwarf HD 260655 (GJ 239, TOI-4599). The system consists of at least two transiting planets, namely HD 260655 b, with a period of 2.77 d, a radius of R$_b$ = 1.240$\pm$0.023 R$_\oplus$, a mass of M$_b$ = 2.14$\pm$0.34 M$_\oplus$, and a bulk density of $\rho_b$ = 6.2$\pm$1.0 g cm$^{-3}$, and HD 260655 c, with a period of 5.71 d, a radius of R$_c$ = 1.533$^{+0.051}_{-0.046}$ R$_\oplus$, a mass of M$_c$ = 3.09$\pm$0.48 M$_\oplus$, and a bulk density of $\rho_c$ = 4.7$^{+0.9}_{-0.8}$ g cm$^{-3}$. The planets were detected in transit by the TESS mission and confirmed independently with archival and new precise radial velocities obtained with the HIRES and CARMENES instruments since 1998 and 2016, respectively. At a distance of 10 pc, HD 260655 becomes the fourth closest known multi-transiting planet system after HD 219134, LTT 1445 A, and AU Mic. Due to the apparent brightness of the host star (J = 6.7 mag), both planets are among the most suitable rocky worlds known today for atmospheric studies with the JWST, both in transmission and emission., Comment: 24 pages, 17 figures. Accepted for publication in A&A

Published
2022
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7. Energetic nuclear transients in luminous and ultraluminous infrared galaxies

Author

Reynolds, T. M., Mattila, S., Kankare, E., Efstathiou, A., Kool, E., Ryder, S., Peña-Moñino, L., and Pérez-Torres, M. A.

Subjects
Astrophysics - Astrophysics of Galaxies, Astrophysics - High Energy Astrophysical Phenomena
Abstract

Energetic nuclear outbursts have been discovered in luminous and ultraluminous infrared galaxies (U/LIRGs) at unexpectedly high rates. To investigate this population of transients, we performed a search in mid-IR data from the Wide-field Infrared Survey Explorer (WISE) satellite and its NEOWISE survey to detect and characterise luminous and smoothly evolving transients in a sample of 215 U/LIRGs. We report three new transients, all with $\Delta L > 10^{43}$ erg s$^{-1}$, in addition to two previously known cases. Their host galaxies are all part of major galaxy mergers, and through radiative transfer model fitting we find that all have a significant contribution from an active galactic nucleus (AGN). We characterised the transients through measurements of their luminosities and resulting energetics, all of which are between 10$^{50.9}$ erg and 10$^{52.2}$ erg. The IR emission of the five transients was found to be consistent with re-radiation by the hot dust of emission at shorter wavelengths, presumably originating from an accretion event, onto the supermassive black hole. The corresponding transient rate of (1.6-4.6)$\times$10$^{-3}$ / yr / galaxy is over an order of magnitude higher than the rate of large amplitude flares shown by AGN in the optical. We suggest that the observed transients are part of a dust-obscured population of tidal disruption events (TDEs) that have remained out of the reach of optical surveys due to the obscuring dust. In one case, this is supported by our radio observations. We also discuss other plausible explanations. The observed rate of events is significantly higher than optical TDE rates, which can be expected in U/LIRG hosts undergoing a major galaxy merger with increased stellar densities in the nuclear regions. Continued searches for such transients and their multi-wavelength follow-up is required to constrain their rate and nature., Comment: 15 pages; 8 figures, published by A&A. Re-uploaded to reflect published version. Main changes from previous version are expanded radio analysis and slightly altered rate due to additional year of NEOWISE data

Published
2022
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18. PERcutaneous transhepatic cholangioscopy using a new single-operator short CHOLangioscope (PERCHOL): a European feasibility study

Author

Perez-Cuadrado-Robles, E., additional, Phillpotts, S., additional, Bronswijk, M., additional, Conrad, C. Cim, additional, Binda, C., additional, Monino, L., additional, Basiliya, K., additional, Hollenbach, M., additional, Papaefthymiou, A., additional, Alric, H., additional, Quénéhervé, L., additional, Di Gaeta, A., additional, Mathieu, P., additional, Khani, A., additional, Lorenzo, D., additional, Moreels, T., additional, Rahmi, G., additional, Carlo, F., additional, Prat, F., additional, Laleman, W., additional, Cellier, C., additional, Van der Merwe, S., additional, Webster, G., additional, and Ellrichmann, M., additional

Published
2023
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24. Risk factors of anastomosis related difficult ERCP following EUS-guided gastro-gastrostomy (EDGE) using a standardized protocol

Author

Perez-Cuadrado-Robles, E., additional, Alric, H., additional, Quénéhervé, L., additional, Monino, L., additional, Poghosyan, T., additional, Benosman, H., additional, Vienne, A., additional, Perrod, G., additional, Rebibo, L., additional, Ali, A., additional, Gonzalez, E. Tenorio, additional, Ragot, E., additional, Karoui, M., additional, Cellier, C., additional, and Rahmi, G., additional

Published
2023
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40. Alternative endoscopic salvage therapies using lumen-apposing metal stents for stent misdeployment during endoscopic ultrasound-directed transgastric intervention.

Author

Monino L, Marique L, Deswysen Y, Navez B, Danse E, and Moreels T

Abstract

Competing Interests: L. Monino is a consultant for Taewoong Medical, Fujifilm and Prion Medical, and has received speaker’s fees from Olympus Belgium and Olympus Europe. T. G. Moreels has received speaker’s fees from Olympus Belgium and Olympus Europe. L. Marique, Y. Deswysen, B. Navez, and E. Danse declare that they have no conflict of interest.

Published
2024
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41. Endoscopic ultrasound-guided gastroenterostomy to treat obstructive gastric twist after laparoscopic sleeve gastrectomy.

Author

Monino L, Deswysen Y, Thoma M, Deprez PH, and Moreels T

Subjects
Humans, Ultrasonography, Interventional, Female, Gastric Outlet Obstruction etiology, Gastric Outlet Obstruction surgery, Middle Aged, Adult, Gastrectomy methods, Gastrectomy adverse effects, Gastroenterostomy methods, Gastroenterostomy adverse effects, Endosonography methods, Laparoscopy methods
Abstract

Competing Interests: LM is consultant for Prion Medical and Braun Medical and received speaker’s fees from Olympus Belgium and Olympus Europe. PHD is consultant for Boston Scientific TGM received speaker’s fees from Olympus Belgium and Olympus Europe. Others authors declare that they have no conflict of interest.

Published
2024
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42. Endoscopic Management of Biliary and Pancreatic Pathologies in Roux-en-Y Gastric Bypass Patients: Development of a Treatment Algorithm Based on 9-Year Experience.

Author

Monino L, Marique L, Deswysen Y, Thoma M, Deprez PH, Goffette P, Navez B, and Moreels TG

Subjects
Humans, Female, Middle Aged, Retrospective Studies, Male, Pancreatic Diseases surgery, Treatment Outcome, Postoperative Complications epidemiology, Balloon Enteroscopy methods, Endosonography, Adult, Biliary Tract Diseases surgery, Biliary Tract Diseases etiology, Gastric Bypass methods, Algorithms, Cholangiopancreatography, Endoscopic Retrograde methods, Obesity, Morbid surgery, Laparoscopy methods
Abstract

Background: Management of biliopancreatic pathology in Roux-en-Y gastric bypass (RYGB) patients is challenging despite the availability of multiple approaches like single-balloon enteroscopy-assisted ERCP (SBE-ERCP), laparoscopy-assisted ERCP (LA-ERCP), and EUS-directed transgastric intervention (EDGI). We evaluated the outcomes of the interchangeable combination of endoscopic procedures to treat biliopancreatic pathology in RYGB patients., Materials and Methods: This is a monocentric retrospective study of consecutive RYGB patients with biliopancreatic pathology between June 2014 and September 2023. Primary endpoints were technical success, adverse events (AE), and parameters of endoscopic procedures according to etiology. A clinically useful management algorithm was developed., Results: A total of 102 patients with RYGB (73 women; mean age 55 ± 10 years) were included. A total of 113 SBE-ERCP (in 90 patients), 26 EDGI (in 23 patients), and 2 LA-ERCP (in 2 patients) were performed. Technical success of SBE-ERCP was lower compared to EDGI (74.4% vs 95.1%, p = 0.002). The AE rate was lower using SBE-ERCP compared to EDGI (12.4% vs 38.5%, p = 0.003). Two sub-groups based on etiology were identified as "common bile duct stone" (CBDS) and "Other." In the CBDS group, the mean number and time of procedures were lower in SBE-ERCP as the first-line technique compared to first-line EDGI (1.1 vs 2.7, p < 0.00 and 91 ± 20.7 min vs 161 ± 61.3 min, p < 0.00)., Conclusion: A combination of endoscopic procedures can achieve high technical success in managing biliopancreatic pathology in RYGB patients with an acceptable AE rate. In the case of CBDS, SBE-ERCP appeared to be a good first-line single-step option. For other indications, EDGI should be proposed as the first line., (© 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)

Published
2024
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43. Endoscopic treatment of biliopancreatic pathology in patients with Whipple's pancreaticoduodenectomy surgical variants: Lessons learned from single-balloon enteroscopy-assisted ERCP.

Author

Garcés-Durán R, Monino L, Deprez PH, Piessevaux H, and Moreels TG

Subjects
Humans, Male, Female, Middle Aged, Retrospective Studies, Aged, Treatment Outcome, Adult, Biliary Tract Diseases surgery, Biliary Tract Diseases etiology, Pancreatic Diseases surgery, Pancreatic Diseases diagnostic imaging, Aged, 80 and over, Pancreaticoduodenectomy adverse effects, Pancreaticoduodenectomy methods, Cholangiopancreatography, Endoscopic Retrograde adverse effects, Single-Balloon Enteroscopy adverse effects, Single-Balloon Enteroscopy methods, Feasibility Studies
Abstract

Background: Endoscopic treatment of biliopancreatic pathology is challenging due to surgically altered anatomy after Whipple's pancreaticoduodenectomy. This study aimed to evaluate the feasibility and safety of single-balloon enteroscopy-assisted endoscopic retrograde cholangiopancreatography (SBE-ERCP) to treat biliopancreatic pathology in patients with Whipple's pancreaticoduodenectomy surgical variants., Methods: We retrospectively analyzed 106 SBE-ERCP procedures in 46 patients with Whipple's variants. Technical and clinical success rates and adverse events were evaluated., Results: Biliary SBE-ERCP was performed in 34 patients and pancreatic SBE-ERCP in 17, including 5 with both indications. From a total of 106 SBE-ERCP procedures, 76 were biliary indication with technical success rate of 68/76 (90%) procedures and clinical success rate of 30/34 (88%) patients. Mild adverse event rate was 8/76 (11%), without serious adverse events. From a total of 106 SBE-ERCP procedures, 30 were pancreatic indication with technical success rate of 24/30 (80%) procedures (P = 0.194 vs. biliary SBE-ERCP) and clinical success rate of 11/17 (65%) patients (P = 0.016 vs. biliary SBE-ERCP). Mild adverse event rate was 6/30 (20%) (P = 0.194 vs. biliary SBE-ERCP), without serious adverse events. After SBE-ERCP failure, endoscopic ultrasound-guided drainage, percutaneous drainage and redo surgery were alternative therapeutic options., Conclusions: Biliopancreatic pathology after Whipple's pancreaticoduodenectomy variants can be treated using SBE-ERCP without serious adverse events. Technical and clinical success rates are high for biliary indications, whereas clinical success rate of pancreatic indications is significantly lower. SBE-ERCP can be considered as first-line treatment option in this patient group with surgically altered anatomy., (Copyright © 2023 First Affiliated Hospital, Zhejiang University School of Medicine in China. Published by Elsevier B.V. All rights reserved.)

Published
2024
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44. PERcutaneous transhepatic CHOLangioscopy using a new single-operator short cholangioscope (PERCHOL): European feasibility study.

Author

Pérez-Cuadrado-Robles E, Phillpotts S, Bronswijk M, Conrad CC, Binda C, Monino L, Basiliya K, Hollenbach M, Papaefthymiou A, Alric H, Quénéhervé L, Di Gaeta A, Pioche M, Khani A, Lorenzo D, Moreels TG, Rahmi G, Boeken T, Fabbri C, Prat F, Laleman W, Cellier C, Van der Merwe S, Webster G, and Ellrichmann M

Subjects
Humans, Male, Middle Aged, Female, Retrospective Studies, Aged, Europe, Equipment Design, Adult, Feasibility Studies, Endoscopy, Digestive System instrumentation, Endoscopy, Digestive System methods
Abstract

Objectives: A new short device for percutaneous endoscopic cholangioscopy was recently developed. However, feasibility and safety has not yet been evaluated. The aim of this study was to assess clinical success, technical success, and adverse events (AEs)., Methods: This observational multicenter retrospective study included all patients who underwent percutaneous cholangioscopy using a short cholangioscope between 2020 and 2022. The clinical success, defined as the complete duct clearance or obtaining at least one cholangioscopy-guided biopsy, was assessed. The histopathological accuracy, technical success, and the AE rate were also evaluated., Results: Fifty-one patients (60 ± 15 years, 45.1% male) were included. The majority of patients had altered anatomy (n = 40, 78.4%), and biliary stones (n = 34, 66.7%) was the commonest indication. The technique was predominantly wire-guided (n = 44, 86.3%) through a percutaneous sheath (n = 36, 70.6%) following a median interval of 8.5 days from percutaneous drainage. Cholangioscopy-guided electrohydraulic lithotripsy was performed in 29 cases (56.9%), combined with a retrieval basket in eight cases (27.6%). The clinical success was 96.6%, requiring a median of one session (range 1-3). Seventeen patients (33.3%) underwent cholangioscopy-guided biopsies. There were four (7.8%) cholangioscopy-related AEs (cholangitis and peritonitis). Overall, the technical success and AE rates were 100% and 19.6%, respectively, in a median follow-up of 7 months., Conclusion: Percutaneous endoscopic cholangioscopy with a new short device is effective and safe, requiring a low number of sessions to achieve duct clearance or accurate histopathological diagnosis., (© 2023 The Authors. Digestive Endoscopy published by John Wiley & Sons Australia, Ltd on behalf of Japan Gastroenterological Endoscopy Society.)

Published
2024
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45. Patient Radiation Exposure during Enteroscopy-Assisted Endoscopic Retrograde Cholangiopancreatography in Surgically Altered Anatomy (with Video).

Author

Monino L and Moreels TG

Abstract

Background: Fluoroscopy must be used cautiously during endoscopic retrograde cholangiopancreatography (ERCP). Radiation exposure data in patients with surgically altered anatomy undergoing enteroscopy-assisted ERCP (EA-ERCP) are scarce., Methods: 34 consecutive EA-ERCP procedures were compared with 68 conventional ERCP (C-ERCP) procedures. Patient and procedure characteristics and radiation data were collected., Results: Surgical reconstructions were gastrojejunostomy, Roux-en-Y hepaticojejunostomy, Roux-en-Y total gastrectomy, Roux-en-Y gastric bypass and Whipple's duodenopancreatectomy. Procedures were restricted to biliary indications. Mean fluoroscopy time was comparable in both groups (370 ± 30 s EA-ERCP vs. 393 ± 40 s C-ERCP, p = 0.7074), whereas total mean radiation dose was lower in EA-ERCP (83 ± 6 mGy) compared to C-ERCP (110 ± 11 mGy, p = 0.0491) and dose area product (DAP) was higher in EA-ERCP (2216 ± 173 µGy*m 2 ) compared to C-ERCP (1600 ± 117 µGy*m 2 , p = 0.0038), as was total procedure time (77 ± 5 min vs. 39 ± 3 min, p < 0.0001). Enteroscope insertion to reach the bile duct during EA-ERCP took 28 ± 4 min, ranging from 4 to 90 min. These results indicate that C-ERCP procedures are generally more complex, needing magnified fluoroscopy, whereas EA-ERCP procedures take more time for enteroscope insertion under wide field fluoroscopic guidance (increased DAP) with less complex ERCP manipulation (lower total radiation dose)., Conclusions: Radiation exposure during EA-ERCP in surgically altered anatomy is different as compared to C-ERCP. EA-ERCP takes longer with a higher DAP because of the enteroscope insertion, but with lower total radiation dose because these ERCP procedures are usually less complex.

Published
2024
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46. Endoscopic management of complex colorectal anastomotic leakage with a pelvic collection and rectovaginal fistula.

Author

Monino L, Bachmann R, Leonard D, Remue C, Danse E, Kartheuser A, and Moreels T

Subjects
Female, Humans, Rectovaginal Fistula etiology, Rectovaginal Fistula surgery, Rectum surgery, Endoscopy, Anastomosis, Surgical adverse effects, Anastomotic Leak diagnostic imaging, Anastomotic Leak etiology, Anastomotic Leak surgery, Colorectal Neoplasms surgery
Abstract

Competing Interests: L. Monino is consultant for Prion Medical and Braun Medical, and is a speaker for Olympus Belgium and Olympus Europe. T.G. Moreels is a speaker for Olympus Belgium and Olympus Europe. R. Bachmann, D. Leonard, C. Remue, E. Danse, and A. Kartheuser declare that they have no conflict of interest.

Published
2023
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47. Endoscopic ultrasound-guided gastroenterostomy with lumen-apposing metal stents: a retrospective multicentric comparison of wireless and over-the-wire techniques.

Author

Monino L, Perez-Cuadrado-Robles E, Gonzalez JM, Snauwaert C, Alric H, Gasmi M, Ouazzani S, Benosman H, Deprez PH, Rahmi G, Cellier C, Moreels TG, and Barthet M

Subjects
Male, Humans, Aged, Female, Retrospective Studies, Treatment Outcome, Endosonography methods, Stents adverse effects, Ultrasonography, Interventional methods, Gastroenterostomy methods, Gastric Outlet Obstruction etiology
Abstract

Background: Endoscopic ultrasound-guided gastroenterostomy (EUS-GE) using lumen-apposing metal stents (LAMSs) appears to be effective and safe in gastric outlet obstruction (GOO); however, the EUS-GE procedure is not standardized, with the use of assisted or direct methods still debated. The aim of this study was to compare the outcomes of EUS-GE techniques focusing on an assisted with orointestinal drain wireless endoscopic simplified technique (WEST) and the nonassisted direct technique over a guidewire (DTOG)., Method: This was a multicenter European retrospective study involving four tertiary centers. Consecutive patients who underwent EUS-GE for GOO between August 2017 and May 2022 were included. The primary aim was to compare the technical success and adverse event (AE) rates of the different EUS-GE techniques. Clinical success was also analyzed., Results: 71 patients (mean [SD] age 66.2 10 years; 42.3 % men; 80.3 % malignant etiology) were included. Technical success was higher in the WEST group (95.1 % vs. 73.3 %; estimate of relative risk from odds ratio (eRR) 3.2, 95 %CI 0.94-10.9; P  = 0.01). The rate of AEs was lower in the WEST group (14.6 % vs. 46.7 %; eRR 2.3, 95 %CI 1.2-4.5; P  = 0.007). Clinical success was comparable between the two groups at 1 month (97.5 % vs. 89.3 %). The median follow-up was 5 months (range 1-57)., Conclusion: The WEST resulted in a higher technical success rate with fewer AEs, with clinical success comparable with the DTOG. Therefore, the WEST (with an orointestinal drain) should be preferred when performing EUS-GE., Competing Interests: L. Monino is a consultant for Prion Medical and Braun Medical and has received speaker’s fees from Olympus Belgium and Olympus Europe. E. Pérez-Cuadrado-Robles and J.-M. Gonzalez are consultants for Boston Scientific. P. H. Deprez is a consultant for Boston Scientific and Olympus Europe. T. G. Moreels has received speaker’s fees from Olympus Belgium and Olympus Europe. M. Barthet is a consultant for Boston Scientific.C. Snauwaert, H. Alric, M. Gasmi, S. Ouazzani, H. Benosman, G. Rahmi, and C. Cellier declare that they have no conflict of interest., (Thieme. All rights reserved.)

Published
2023
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48. Risk factors of anastomosis-related difficult endoscopic retrograde cholangiopancreatography following endoscopic ultrasound-guided gastro-gastrostomy using a standardized protocol (with video).

Author

Pérez-Cuadrado-Robles E, Alric H, Quénéhervé L, Monino L, Poghosyan T, Benosman H, Vienne A, Perrod G, Rebibo L, Aidibi A, Tenorio-González E, Ragot E, Karoui M, Cellier C, and Rahmi G

Subjects
Aged, Female, Humans, Male, Middle Aged, Endosonography methods, Gastrostomy adverse effects, Observational Studies as Topic, Retrospective Studies, Risk Factors, Stents, Ultrasonography, Interventional, Cholangiopancreatography, Endoscopic Retrograde methods, Gastric Bypass methods
Abstract

Objectives: Little is known about how to perform the endoscopic ultrasound (EUS)-directed transgastric endoscopic retrograde cholangiopancreatography (ERCP; EDGE) in patients with gastric bypass using lumen-apposing metal stents (LAMS). The aim was to assess the risk factors of anastomosis-related difficult ERCP., Methods: Observational single-center study. All patients who underwent an EDGE procedure in 2020-2022 following a standardized protocol were included. Risk factors for difficult ERCP, defined as the need of >5 min LAMS dilation or failure to pass a duodenoscope in the second duodenum, were assessed., Results: Forty-five ERCPs were performed in 31 patients (57.4 ± 8.2 years old, 38.7% male). The EUS procedure was done using a wire-guided technique (n = 28, 90.3%) for biliary stones (n = 22, 71%) in most cases. The location of the anastomosis was gastro-gastric (n = 24, 77.4%) and mainly in the middle-excluded stomach (n = 21, 67.7%) with an oblique axis (n = 22, 71%). The ERCP technical success was 96.8%. There were 10 difficult ERCPs (32.3%) due to timing (n = 8), anastomotic dilation (n = 8), or failure to pass (n = 3). By multivariable analysis adjusted by two-stage procedures, the risk factors for a difficult ERCP were the jejuno-gastric route (85.7% vs. 16.7%; odds ratio [OR a ] 31.875; 95% confidence interval [CI] 1.649-616.155; P = 0.022), and the anastomosis to the proximal/distal excluded stomach (70% vs. 14.3%; OR a 22.667; 95% CI 1.676-306.570; P = 0.019). There was only one complication (3.2%) and one persistent gastro-gastric fistula (3.2%) in a median follow-up of 4 months (2-18 months), with no weight regain (P = 0.465)., Conclusions: The jejunogastric route and the anastomosis with the proximal/distal excluded stomach during the EDGE procedure increase the difficulty of ERCP., (© 2023 The Authors. Digestive Endoscopy published by John Wiley & Sons Australia, Ltd on behalf of Japan Gastroenterological Endoscopy Society.)

Published
2023
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49. Peroral endoscopic myotomy and valve section for treatment of persistent and disabling dysphagia after laparoscopic fundoplication (with video).

Author

Gonzalez JM, Barthet M, Debourdeau A, Monino L, and Vitton V

Abstract

Background and Aims: The use of laparoscopic fundoplication (LF) to treat refractory GERD may induce refractory dysphagia (5%-10%). The management is complex, and peroral endoscopic myotomy (POEM) including valve incision is a new therapeutic option., Methods: This retrospective study involved patients with postfundoplication refractory dysphagia treated by POEM associated with complete wrap incision. Patients were evaluated with Eckardt and dysphagia scores. Study objectives were to evaluate clinical and technical outcomes, adverse events, and GERD recurrence., Results: Twenty-six patients, with a mean age of 57.3 ± 15.6 years, were included. Mean follow-up was 25.3 ± 17.6 months. The technical and clinical success rates were 96% and 84.6%, respectively. Among failures, 1 patient underwent Lewis-Santy, 2 required dilations, and 1 was lost to follow-up. Three late recurrences occurred and were endoscopically managed. Five patients (19%) had GERD recurrence that was mainly improved by proton pump inhibitors., Conclusions: POEM with fundoplication is a serious therapeutic option for managing persistent dysphagia after LF, with a low risk of GERD recurrence., Competing Interests: Disclosure The following authors disclosed financial relationships: J-M. Gonzalez: Consultant for Boston Scientific and Fujifilm. M. Barthet: Consultant for Boston Scientific. All other authors disclosed no financial relationships., (Copyright © 2023 American Society for Gastrointestinal Endoscopy. Published by Elsevier Inc. All rights reserved.)

Published
2023
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50. Endoscopic Vacuum Therapy of Upper Gastrointestinal Anastomotic Leaks: How to Deal with the Challenges (with Video).

Author

Monino L and Moreels TG

Abstract

Anastomotic leaks after gastrointestinal surgery have an important impact on surgical outcomes because of the high morbidity and mortality rates. Multiple treatment options exist requiring an individualized patient-tailored treatment plan after multidisciplinary discussion. Endoscopic vacuum therapy (EVT) is a novel treatment option that is nowadays recognized as an effective and useful endoscopic approach to treat leaks or perforations in both the upper and lower gastrointestinal tract. EVT has a very good safety profile. However, it is a time-consuming endeavour requiring engagement from the endoscopist and understanding from the patient. To the unexperienced, the EVT technique may be prone to several hurdles which may deter endoscopists from using it and depriving patients from a potentially life-saving therapeutic option. The current review highlights the possible difficulties of the EVT procedure and aims to provide some practical solutions to facilitate its use in daily clinical practice. Personal tips and tricks are shared to overcome the pre-, intra- and post-procedural hurdles. An instructive video of the procedure helps to illustrate the technique of EVT.

Published
2023
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