23,401 results on '"Morabito A"'
Search Results
2. HETDEX-LOFAR Spectroscopic Redshift Catalog
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Debski, Maya H., Zeimann, Gregory R., Hill, Gary J., Schneider, Donald P., Morabito, Leah, Dalton, Gavin, Jarvis, Matt J., Cooper, Erin Mentuch, Ciardullo, Robin, Gawiser, Eric, and Jurlin, Nika
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Astrophysics - Astrophysics of Galaxies - Abstract
We combine the power of blind integral field spectroscopy from the Hobby-Eberly Telescope (HET) Dark Energy Experiment (HETDEX) with sources detected by the Low Frequency Array (LOFAR) to construct the HETDEX-LOFAR Spectroscopic Redshift Catalog. Starting from the first data release of the LOFAR Two-metre Sky Survey (LoTSS), including a value-added catalog with photometric redshifts, we extracted 28,705 HETDEX spectra. Using an automatic classifying algorithm, we assigned each object a star, galaxy, or quasar label along with a velocity/redshift, with supplemental classifications coming from the continuum and emission line catalogs of the internal, fourth data release from HETDEX (HDR4). We measured 9,087 new redshifts; in combination with the value-added catalog, our final spectroscopic redshift sample is 9,710 sources. This new catalog contains the highest substantial fraction of LOFAR galaxies with spectroscopic redshift information; it improves archival spectroscopic redshifts, and facilitates research to determine the [O II] emission properties of radio galaxies from $0.0 < z < 0.5$, and the Ly$\alpha$ emission characteristics of both radio galaxies and quasars from $1.9 < z < 3.5$. Additionally, by combining the unique properties of LOFAR and HETDEX, we are able to measure star formation rates (SFR) and stellar masses. Using the Visible Integral-field Replicable Unit Spectrograph (VIRUS), we measure the emission lines of [O III], [Ne III], and [O II] and evaluate line-ratio diagnostics to determine whether the emission from these galaxies is dominated by AGN or star formation and fit a new SFR-L$_{150MHz}$ relationship., Comment: 21 pages, 17 figures, submitted to ApJ
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- 2024
3. A spatially-resolved spectral analysis of giant radio galaxies with MeerKAT
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Charlton, K. K. L., Delhaize, J., Thorat, K., Heywood, I., Jarvis, M. J., Hardcastle, M. J., An, Fangxia, Delvecchio, I., Hale, C. L., Whittam, I. H., Brüggen, M., Marchetti, L., Morabito, L., Randriamanakoto, Z., White, S. V., and Taylor, A. R.
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Astrophysics - Astrophysics of Galaxies - Abstract
In this study we report spatially resolved, wideband spectral properties of three giant radio galaxies (GRGs) in the COSMOS field: MGTC J095959.63+024608.6 , MGTC J100016.84+015133.0 and MGTC J100022.85+031520.4. One such galaxy MGTC J100022.85+031520.4 is reported here for the first time with a projected linear size of 1.29 Mpc at a redshift of 0.1034. Unlike the other two, it is associated with a brightest cluster galaxy (BCG), making it one of the few GRGs known to inhabit cluster environments. We examine the spectral age distributions of the three GRGs using new MeerKAT UHF-band (544-1088 MHz) observations, and $L$-band (900-1670 MHz) data from the MeerKAT International GHz Tiered Extragalactic Exploration (MIGHTEE) survey. We test two different models of spectral ageing, the Jaffe-Perola and Tribble models, using the Broadband Radio Astronomy Tools (\textsc{brats}) software which we find agree well with each other. We estimate the Tribble spectral age for MGTC J095959.63+024608.6 as 68 Myr, MGTC J100016.84+015133.0 as 47 Myr and MGTC J100022.85+031520.4 as 67 Myr. We find significant disagreements between these spectral age estimates and the estimates of the dynamical ages of these GRGs, modelled in cluster and group environments. Our results highlight the need for additional processes which are not accounted for in either the dynamic age or spectral age estimations., Comment: 13 pages, 9 figures. Accepted for publication in MNRAS
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- 2024
4. A hidden Active Galactic Nuclei population: the first radio luminosity functions constructed by physical process
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Morabito, Leah K., Kondapally, R., Best, P. N., Yue, B. -H., de Jong, J. M. G. H. J., Sweijen, F., Bondi, Marco, Schwarz, Dominik J., Smith, D. J. B., van Weeren, R. J., Röttgering, H. J. A., Shimwell, T. W., and Prandoni, Isabella
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Astrophysics - Astrophysics of Galaxies - Abstract
Both star formation (SF) and Active Galactic Nuclei (AGN) play an important role in galaxy evolution. Statistically quantifying their relative importance can be done using radio luminosity functions. Until now these relied on galaxy classifications, where sources with a mixture of radio emission from SF and AGN are labelled as either a star-forming galaxy or an AGN. This can cause the misestimation of the relevance of AGN. Brightness temperature measurements at 144 MHz with the International LOFAR telescope can separate radio emission from AGN and SF. We use the combination of sub-arcsec and arcsec resolution imaging of 7,497 sources in the Lockman Hole and ELAIS-N1 fields to identify AGN components in the sub-arcsec resolution images and subtract them from the total flux density, leaving flux density from SF only. We construct, for the first time, radio luminosity functions by physical process, either SF or AGN activity, revealing a hidden AGN population at $L_{\textrm{144MHz}}$$<10^{24}$ W$\,$Hz$^{-1}$ . This population is 1.56$\pm$0.06 more than expected for $0.5
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- 2024
5. Hamiltonian Braids via Generating Functions
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Morabito, Francesco
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Mathematics - Symplectic Geometry ,53D40, 37E30 - Abstract
Given a compactly supported Hamiltonian diffeomorphism of the plane, one can define a generating function for it. In this paper, we show how generating functions retain information about the braid type of collections of fixed points of Hamiltonian diffeomorphisms. One the one hand, we show that it is possible to define a filtration keeping track of linking numbers of pairs of fixed points on the Morse complex of the generating function. On the other, we provide a finite-dimensional proof of a Theorem by Alves and Meiwes about the lower-semicontinuity of the topological entropy with respect to the Hofer norm. The technical tools come from work by Le Calvez which was developed in the 90s. In particular, we apply a version of positivity of intersections for generating functions., Comment: 44 pages, 1 figure. Comments welcome!
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- 2024
6. STOP! Benchmarking Large Language Models with Sensitivity Testing on Offensive Progressions
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Morabito, Robert, Madhusudan, Sangmitra, McDonald, Tyler, and Emami, Ali
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Computer Science - Computation and Language ,Computer Science - Artificial Intelligence ,Computer Science - Computers and Society - Abstract
Mitigating explicit and implicit biases in Large Language Models (LLMs) has become a critical focus in the field of natural language processing. However, many current methodologies evaluate scenarios in isolation, without considering the broader context or the spectrum of potential biases within each situation. To address this, we introduce the Sensitivity Testing on Offensive Progressions (STOP) dataset, which includes 450 offensive progressions containing 2,700 unique sentences of varying severity that progressively escalate from less to more explicitly offensive. Covering a broad spectrum of 9 demographics and 46 sub-demographics, STOP ensures inclusivity and comprehensive coverage. We evaluate several leading closed- and open-source models, including GPT-4, Mixtral, and Llama 3. Our findings reveal that even the best-performing models detect bias inconsistently, with success rates ranging from 19.3% to 69.8%. We also demonstrate how aligning models with human judgments on STOP can improve model answer rates on sensitive tasks such as BBQ, StereoSet, and CrowS-Pairs by up to 191%, while maintaining or even improving performance. STOP presents a novel framework for assessing the complex nature of biases in LLMs, which will enable more effective bias mitigation strategies and facilitates the creation of fairer language models., Comment: 9 pages (excluding references), accepted to EMNLP 2024 Main Conference
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- 2024
7. Risk Analysis in Healthcare Organizations: Methodological Framework and Critical Variables
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Pascarella G, Rossi M, Montella E, Capasso A, De Feo G, Botti Snr G, Nardone A, Montuori P, Triassi M, D'Auria S, and Morabito A
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healthcare risk analysis ,risk matrix ,consequences-likelihood analysis. ,Public aspects of medicine ,RA1-1270 - Abstract
Giacomo Pascarella,1 Matteo Rossi,2 Emma Montella,3 Arturo Capasso,2 Gianfranco De Feo,1 Gerardo Botti Snr,1 Antonio Nardone,3 Paolo Montuori,3 Maria Triassi,3 Stefania D’Auria,4 Alessandro Morabito5 1Scientific Directorate, Istituto Nazionale Tumori “Fondazione G. Pascale”, IRCCS, Napoli, Italy; 2Wroclaw School of Banking Wyższa Szkoła Bankowa, Wrocalw, Poland; 3Department of Public Health, Università Federico II, Napoli, Italy; 4Department of Health Management, Istituto Nazionale Tumori, “Fondazione G. Pascale”, IRCCS, Napoli, Italy; 5Thoracic Department, Istituto Nazionale Tumori “Fondazione G. Pascale” IRCCS, Napoli, ItalyCorrespondence: Giacomo PascarellaScientific Directorate, Istituto Nazionale Tumori “Fondazione G. Pascale”, IRCCS, Via Mariano Semmola, 52, Napoli, 80131, ItalyEmail g.pascarella@istitutotumori.na.itPurpose: A risk assessment matrix is a widely used tool for analyzing, assessing and setting priorities in risk management in many fields. This paper overviews critical variables, advantages, disadvantages, strengths and weaknesses of this tool, according to the ISO 31000 risk management framework.Results: Risk assessment is one of the key stages in the Risk Management Process and involves specific steps: identifying hazards, analyzing and evaluating all possible risks. Several methods are developed to assess risks in the literature. A risk matrix method, also called “decision matrix risk assessment (DMRA) technique”, is a systematic approach used to determine the risk level and to compare different risks and define which threats need to be controlled first. The actors involved in risk assessment are called on to manage different issues related to the choice of the most appropriate methodological approach, the assessment of the adequacy of the existing control measures, the articulation of risk consequence domains, the definition of the impact-consequences, the explanation of risk likelihood scales and the development of a risk matrix.Conclusion: We highlighted a number of recommendations in order to address these issues, especially useful when healthcare organizations provide insufficient guidance on how to use risk matrices as well as what to do in response to the existing criticisms on their use.Keywords: healthcare risk analysis, risk matrix, consequences-likelihood analysis
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- 2021
8. ADformer: A Multi-Granularity Transformer for EEG-Based Alzheimer's Disease Assessment
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Wang, Yihe, Mammone, Nadia, Petrovsky, Darina, Tzallas, Alexandros T., Morabito, Francesco C., and Zhang, Xiang
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Electrical Engineering and Systems Science - Signal Processing ,Computer Science - Computational Engineering, Finance, and Science ,Computer Science - Machine Learning - Abstract
Electroencephalogram (EEG) has emerged as a cost-effective and efficient method for supporting neurologists in assessing Alzheimer's disease (AD). Existing approaches predominantly utilize handcrafted features or Convolutional Neural Network (CNN)-based methods. However, the potential of the transformer architecture, which has shown promising results in various time series analysis tasks, remains underexplored in interpreting EEG for AD assessment. Furthermore, most studies are evaluated on the subject-dependent setup but often overlook the significance of the subject-independent setup. To address these gaps, we present ADformer, a novel multi-granularity transformer designed to capture temporal and spatial features to learn effective EEG representations. We employ multi-granularity data embedding across both dimensions and utilize self-attention to learn local features within each granularity and global features among different granularities. We conduct experiments across 5 datasets with a total of 525 subjects in setups including subject-dependent, subject-independent, and leave-subjects-out. Our results show that ADformer outperforms existing methods in most evaluations, achieving F1 scores of 75.19% and 93.58% on two large datasets with 65 subjects and 126 subjects, respectively, in distinguishing AD and healthy control (HC) subjects under the challenging subject-independent setup., Comment: 17 pages main paper + 3 pages supplementary materials. This work will submit to the IEEE for possible publication
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- 2024
9. Environments of luminous low-frequency radio galaxies since cosmic noon: jet-mode feedback dominates in groups
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Petter, Grayson C., Hickox, Ryan C., Morabito, Leah K., and Alexander, David M.
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Astrophysics - Astrophysics of Galaxies - Abstract
Coupling between relativistic jets launched by accreting supermassive black holes and the surrounding gaseous media is a vital ingredient in galaxy evolution models. To constrain the environments in which this feedback takes place over cosmic time, we study the host halo properties of luminous low-frequency radio galaxies ($L_{150 \ \mathrm{MHz}} \gtrsim$ 25.25 W/Hz) selected with the International LOFAR Telescope out to $z \sim 2$ through tomographic clustering and cosmic microwave background lensing measurements. We find that these systems occupy halos characteristic of galaxy groups ($M_h = 10^{13} - 10^{14} h^{-1} M_{\odot}$), evolving at a rate consistent with the mean growth rate of halos over the past $\sim$10 Gyr. The coevolution of the clustering and the luminosity function reveals that the duty cycle of these systems is of order $\sim 10\%$ but has been mildly increasing since $z\sim 2$, while the duty cycle of quasars has been declining. We estimate the characteristic kinetic heating power injected by powerful jets per halo as a function of mass, and compare to the same quantity injected by quasar winds. We find that powerful jet heating dominates over quasar winds in halos $M_h \gtrsim 10^{13} h^{-1} M_{\odot}$ at $z < 2$. These results conform to the paradigm of galaxy evolution in which mechanical jet power feedback is the dominant heating mechanism of the gas content of groups and clusters., Comment: Accepted to ApJ
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- 2024
10. Future-Proofing Mobile Networks: A Digital Twin Approach to Multi-Signal Management
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Morabito, Roberto, Pandey, Bivek, Daubaris, Paulius, Wanigarathna, Yasith R, and Tarkoma, Sasu
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Computer Science - Networking and Internet Architecture ,Computer Science - Artificial Intelligence - Abstract
Digital Twins (DTs) are set to become a key enabling technology in future wireless networks, with their use in network management increasing significantly. We developed a DT framework that leverages the heterogeneity of network access technologies as a resource for enhanced network performance and management, enabling smart data handling in the physical network. Tested in a Campus Area Network environment, our framework integrates diverse data sources to provide real-time, holistic insights into network performance and environmental sensing. We also envision that traditional analytics will evolve to rely on emerging AI models, such as Generative AI (GenAI), while leveraging current analytics capabilities. This capacity can simplify analytics processes through advanced ML models, enabling descriptive, diagnostic, predictive, and prescriptive analytics in a unified fashion. Finally, we present specific research opportunities concerning interoperability aspects and envision aligning advancements in DT technology with evolved AI integration., Comment: A shortened version of this paper is currently under review for publication in an IEEE magazine. If accepted, the copyright will be transferred to IEEE
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- 2024
11. Into the depths: Unveiling ELAIS-N1 with LOFAR's deepest sub-arcsecond wide-field images
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de Jong, J. M. G. H. J., van Weeren, R. J., Sweijen, F., Oonk, J. B. R., Shimwell, T. W., Offringa, A. R., Morabito, L. K., Röttgering, H. J. A., Kondapally, R., Escott, E. L., Best, P. N., Bondi, M., Ye, H., and Petley, J. W.
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Astrophysics - Instrumentation and Methods for Astrophysics ,Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
We present the deepest wide-field 115-166 MHz image at sub-arcsecond resolution spanning an area of 2.5 by 2.5 degrees centred at the ELAIS-N1 deep field. To achieve this, we improved the calibration for the International LOFAR Telescope. This enhancement enabled us to efficiently process 32 hrs of data from four different 8-hr observations using the high-band antennas (HBAs) of all 52 stations, covering baselines up to approximately 2,000 km across Europe. The DI calibration was improved by using an accurate sky model and refining the series of calibration steps on the in-field calibrator, while the DD calibration was improved by adopting a more automated approach for selecting the DD calibrators and inspecting the self-calibration on these sources. We also added an additional round of self-calibration for the Dutch core and remote stations in order to refine the solutions for shorter baselines. To complement our highest resolution at 0.3", we also made intermediate resolution wide-field images at 0.6" and 1.2". Our resulting wide-field images achieve a central noise level of 14 muJy/beam at 0.3", doubling the depth and uncovering four times more objects than the Lockman Hole deep field image at comparable resolution but with only 8 hrs of data. Compared to LOFAR imaging without the international stations, we note that due to the increased collecting area and the absence of confusion noise, we reached a point-source sensitivity comparable to a 500-hr ELAIS-N1 6" image with 16 times less observing time. Importantly, we have found that the computing costs for the same amount of data are almost halved (to about 139,000 CPU hrs per 8 hrs of data) compared to previous efforts, though they remain high. Our work underscores the value and feasibility of exploiting all Dutch and international LOFAR stations to make deep wide-field images at sub-arcsecond resolution., Comment: Images and catalogues will be available on https://lofar-surveys.org/hd-en1.html
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- 2024
12. Exploring the Boundaries of On-Device Inference: When Tiny Falls Short, Go Hierarchical
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Behera, Adarsh Prasad, Daubaris, Paulius, Bravo, Iñaki, Gallego, José, Morabito, Roberto, Widmer, Joerg, and Champati, Jaya Prakash Varma
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Computer Science - Machine Learning ,Computer Science - Distributed, Parallel, and Cluster Computing - Abstract
On-device inference holds great potential for increased energy efficiency, responsiveness, and privacy in edge ML systems. However, due to less capable ML models that can be embedded in resource-limited devices, use cases are limited to simple inference tasks such as visual keyword spotting, gesture recognition, and predictive analytics. In this context, the Hierarchical Inference (HI) system has emerged as a promising solution that augments the capabilities of the local ML by offloading selected samples to an edge server or cloud for remote ML inference. Existing works demonstrate through simulation that HI improves accuracy. However, they do not account for the latency and energy consumption on the device, nor do they consider three key heterogeneous dimensions that characterize ML systems: hardware, network connectivity, and models. In contrast, this paper systematically compares the performance of HI with on-device inference based on measurements of accuracy, latency, and energy for running embedded ML models on five devices with different capabilities and three image classification datasets. For a given accuracy requirement, the HI systems we designed achieved up to 73% lower latency and up to 77% lower device energy consumption than an on-device inference system. The key to building an efficient HI system is the availability of small-size, reasonably accurate on-device models whose outputs can be effectively differentiated for samples that require remote inference. Despite the performance gains, HI requires on-device inference for all samples, which adds a fixed overhead to its latency and energy consumption. Therefore, we design a hybrid system, Early Exit with HI (EE-HI), and demonstrate that compared to HI, EE-HI reduces the latency by up to 59.7% and lowers the device's energy consumption by up to 60.4%.
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- 2024
13. Multiple effectiveness aspects of tapentadol for moderate–severe cancer-pain treatment: an observational prospective study
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Cascella M, Forte CA, Bimonte S, Esposito G, Romano C, Costanzo R, Morabito A, and Cuomo A
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tapentadol ,cancer pain ,pain treatment ,quality of life ,neuropathic pain ,Medicine (General) ,R5-920 - Abstract
M Cascella,1 CA Forte,1 S Bimonte,1 G Esposito,1 C Romano,2 R Costanzo,2 A Morabito,2 A Cuomo1 1Department of Anesthesia and Pain Medicine, Istituto Nazionale Tumori, IRCCS – Fondazione G Pascale, Naples, Italy; 2Thoracic Medical Oncology, Istituto Nazionale Tumori, IRCCS – Fondazione G Pascale, Naples, Italy Background: Previous studies have shown the efficacy of tapentadol (TP) for chronic cancer pain. We evaluated multiple effectiveness aspects of TP prolonged release on moderate–severe cancer-related pain, neuropathic pain (NeP), patient satisfaction, and quality of life. Methods: An observational prospective study was conducted on 80 cancer patients. Opioid-naïve patients received a starting dose of prolonged-release TP 50 mg twice daily, and opioid-experienced patients were switched to TP, not to exceed 500 mg/day. Treatment response was evaluated at 3, 6, 30–40, and 60–70 days through response rate, numeric rating-scale scoring, survival analysis (time to event for response), pain-intensity difference, TP escalation-index percentage, and effects on NeP. The drug-sparing effect on concomitant therapies was evaluated. Results: Seventy of 80 patients (88%) were responders to treatment (95% CI 78%–94%). Compared to T0, pain-intensity reductions were statistically significant for all intervals (P
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- 2018
14. Confidence Under the Hood: An Investigation into the Confidence-Probability Alignment in Large Language Models
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Kumar, Abhishek, Morabito, Robert, Umbet, Sanzhar, Kabbara, Jad, and Emami, Ali
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Computer Science - Computation and Language ,Computer Science - Artificial Intelligence ,Computer Science - Machine Learning - Abstract
As the use of Large Language Models (LLMs) becomes more widespread, understanding their self-evaluation of confidence in generated responses becomes increasingly important as it is integral to the reliability of the output of these models. We introduce the concept of Confidence-Probability Alignment, that connects an LLM's internal confidence, quantified by token probabilities, to the confidence conveyed in the model's response when explicitly asked about its certainty. Using various datasets and prompting techniques that encourage model introspection, we probe the alignment between models' internal and expressed confidence. These techniques encompass using structured evaluation scales to rate confidence, including answer options when prompting, and eliciting the model's confidence level for outputs it does not recognize as its own. Notably, among the models analyzed, OpenAI's GPT-4 showed the strongest confidence-probability alignment, with an average Spearman's $\hat{\rho}$ of 0.42, across a wide range of tasks. Our work contributes to the ongoing efforts to facilitate risk assessment in the application of LLMs and to further our understanding of model trustworthiness., Comment: 9 pages (excluding references), accepted to ACL 2024 Main Conference
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- 2024
15. The LOFAR Two-metre Sky Survey: The nature of the faint source population and SFR-radio luminosity relation using Prospector
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Das, Soumyadeep, Smith, Daniel J. B., Haskell, Paul, Hardcastle, Martin J., Best, Philip N., Duncan, Kenneth J., Arnaudova, Marina I., Shenoy, Shravya, Kondapally, Rohit, Cochrane, Rachel K., Drake, Alyssa B., Gürkan, Gülay, Małek, Katarzyna, Morabito, Leah K., and Prandoni, Isabella
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Astrophysics - Astrophysics of Galaxies - Abstract
Spectral energy distribution (SED) fitting has been extensively used to determine the nature of the faint radio source population. Recent efforts have combined fits from multiple SED-fitting codes to account for the host galaxy and any active nucleus that may be present. We show that it is possible to produce similar-quality classifications using a single energy-balance SED fitting code, Prospector, to model up to 26 bands of UV$-$far-infrared aperture-matched photometry for $\sim$31,000 sources in the ELAIS-N1 field from the LOFAR Two-Metre Sky Survey (LoTSS) Deep fields first data release. One of a new generation of SED-fitting codes, Prospector accounts for potential contributions from radiative active galactic nuclei (AGN) when estimating galaxy properties, including star formation rates (SFRs) derived using non-parametric star formation histories. Combining this information with radio luminosities, we classify 92 per cent of the radio sources as a star-forming galaxy, high/low-excitation radio galaxy, or radio-quiet AGN and study the population demographics as a function of 150 MHz flux density, luminosity, SFR, stellar mass, redshift and apparent $r$-band magnitude. Finally, we use Prospector SED fits to investigate the SFR$-$150 MHz luminosity relation for a sample of $\sim$$133,000~3.6~\mu$m-selected $z<1$ sources, finding that the stellar mass dependence is significantly weaker than previously reported, and may disappear altogether at $\log_{10} (\mathrm{SFR}/M_\odot~\mathrm{yr}^{-1}) > 0.5$. This approach makes it significantly easier to classify radio sources from LoTSS and elsewhere, and may have important implications for future studies of star-forming galaxies at radio wavelengths., Comment: 20 pages, 13 figures, accepted for publication in MNRAS
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- 2024
16. Follow-Me AI: Energy-Efficient User Interaction with Smart Environments
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Saleh, Alaa, Donta, Praveen Kumar, Morabito, Roberto, Motlagh, Naser Hossein, and Lovén, Lauri
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Computer Science - Distributed, Parallel, and Cluster Computing ,Computer Science - Artificial Intelligence ,Computer Science - Emerging Technologies ,Computer Science - Machine Learning - Abstract
This article introduces Follow-Me AI, a concept designed to enhance user interactions with smart environments, optimize energy use, and provide better control over data captured by these environments. Through AI agents that accompany users, Follow-Me AI negotiates data management based on user consent, aligns environmental controls as well as user communication and computes resources available in the environment with user preferences, and predicts user behavior to proactively adjust the smart environment. The manuscript illustrates this concept with a detailed example of Follow-Me AI in a smart campus setting, detailing the interactions with the building's management system for optimal comfort and efficiency. Finally, this article looks into the challenges and opportunities related to Follow-Me AI.
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- 2024
17. Improved Decision Module Selection for Hierarchical Inference in Resource-Constrained Edge Devices
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Behera, Adarsh Prasad, Morabito, Roberto, Widmer, Joerg, and Champati, Jaya Prakash
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Computer Science - Distributed, Parallel, and Cluster Computing - Abstract
The Hierarchical Inference (HI) paradigm employs a tiered processing: the inference from simple data samples are accepted at the end device, while complex data samples are offloaded to the central servers. HI has recently emerged as an effective method for balancing inference accuracy, data processing, transmission throughput, and offloading cost. This approach proves particularly efficient in scenarios involving resource-constrained edge devices, such as IoT sensors and micro controller units (MCUs), tasked with executing tinyML inference. Notably, it outperforms strategies such as local inference execution, inference offloading to edge servers or cloud facilities, and split inference (i.e., inference execution distributed between two endpoints). Building upon the HI paradigm, this work explores different techniques aimed at further optimizing inference task execution. We propose and discuss three distinct HI approaches and evaluate their utility for image classification.
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- 2024
18. Hofer Energy and Link Preserving Diffeomorphisms in Higher Genus
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Morabito, Francesco and Trifa, Ibrahim
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Mathematics - Symplectic Geometry ,53D40 37E30 - Abstract
Given a pre-monotone Lagrangian link, we obtain Hofer energy estimates for Hamiltonian diffeomorphisms preserving it. Such estimates depend on the braid type of the Hamiltonian diffeomorphism only, and the natural language to talk about this phenomenon is provided by a family of norms on braid groups for surfaces with boundary. This generalises the results obtained by the first author to higher genus surfaces with boundary., Comment: Exposition has been improved and typos have been corrected. No changes to the main result have been made
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- 2024
19. Spatial characterization of debris ejection from the interaction of a tightly focused PW-laser pulse with metal targets
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Vladisavlevici, I. -M., Vlachos, C., Dubois, J. -L., Huerta, A., Agarwal, S., Ahmed, H., Apiñaniz, J. I., Cernaianu, M., Gugiu, M., Krupka, M., Lera, R., Morabito, A., Sangwan, D., Ursescu, D., Curcio, A., Fefeu, N., Pérez-Hernández, J. A., Vacek, T., Vicente, P., Woolsey, N., Gatti, G., Rodríguez-Frías, M. D., Santos, J. J., Bradford, P. W., and Ehret, M.
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Physics - Plasma Physics ,Physics - Applied Physics - Abstract
We present a novel scheme for rapid quantitative analysis of debris generated during experiments with solid targets following relativistic laser-plasma interaction at high-power laser facilities. Experimental data indicates that predictions by available modelling for non-mass-limited targets are reasonable, with debris on the order of hundreds ug-per-shot. We detect for the first time that several % of the debris is ejected directional following the target normal (rear- and interaction side); and confirm previous work that found the debris ejection in direction of the interaction side to be larger than on the side of the target rear.
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- 2024
20. A novel Bayesian approach for decomposing the radio emission of quasars: I. Modelling the radio excess in red quasars
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Yue, B. -H., Best, P. N., Duncan, K. J., Calistro-Rivera, G., Morabito, L. K., Petley, J. W., Prandoni, I., Röttgering, H. J. A., and Smith, D. J. B.
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Astrophysics - Astrophysics of Galaxies - Abstract
Studies show that both radio jets from the active galactic nuclei (AGN) and the star formation (SF) activity in quasar host galaxies contribute to the quasar radio emission; yet their relative contributions across the population remain unclear. Here, we present an improved parametric model that allows us to statistically separate the SF and AGN components in observed quasar radio flux density distributions, and investigate how their relative contributions evolve with AGN bolometric luminosity ($L_\mathrm{bol}$) and redshift ($z$) using a fully Bayesian method. Based on the newest data from LOFAR Two-Metre Sky Survey Data Release 2, our model gives robust fitting results out to $z\sim4$, showing a quasar host galaxy SFR evolution that increases with bolometric luminosity and with redshift out to $z\sim4$. This differs from the global cosmic SFR density, perhaps due to the importance of galaxy mergers. The prevalence of radio AGN emissions increases with quasar luminosity, but has little dependence on redshift. Furthermore, our new methodology and large sample size allow us to subdivide our dataset to investigate the role of other parameters. Specifically, in this paper, we explore quasar colour and demonstrate that the radio excess in red quasars is due to an enhancement in AGN-related emission, since the host galaxy SF contribution to the total radio emission is independent of quasar colour. We also find evidence that this radio enhancement occurs mostly in quasars with weak or intermediate radio power., Comment: Accepted for publication in MNRAS. 19 pages, 13 figures, 1 table
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- 2024
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21. The first high-redshift cavity power measurements of cool-core galaxy clusters with the International LOFAR Telescope
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Timmerman, R., van Weeren, R. J., Botteon, A., Röttgering, H. J. A., Morabito, L. K., and Sweijen, F.
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Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
Radio-mode feedback associated with the active galactic nuclei (AGN) at the cores of galaxy clusters injects large amount of energy into the intracluster medium (ICM), offsetting radiative losses through X-ray emission. This mechanism prevents the ICM from rapidly cooling down and fueling extreme starburst activity as it accretes onto the central galaxies, and is therefore a key ingredient in the evolution of galaxy clusters. However, the influence and mode of feedback at high redshifts (z~1) remains largely unknown. Low-frequency sub-arcsecond resolution radio observations taken with the International LOFAR Telescope have demonstrated their ability to assist X-ray observations with constraining the energy output from the AGNs (or "cavity power") in galaxy clusters, thereby enabling research at higher redshifts than before. In this pilot project, we test this hybrid method on a high redshift (0.6
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- 2024
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22. Spatial and single-nucleus transcriptomic analysis of genetic and sporadic forms of Alzheimer’s disease
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Miyoshi, Emily, Morabito, Samuel, Henningfield, Caden M., Das, Sudeshna, Rahimzadeh, Negin, Shabestari, Sepideh Kiani, Michael, Neethu, Emerson, Nora, Reese, Fairlie, Shi, Zechuan, Cao, Zhenkun, Srinivasan, Shushrruth Sai, Scarfone, Vanessa M., Arreola, Miguel A., Lu, Jackie, Wright, Sierra, Silva, Justine, Leavy, Kelsey, Lott, Ira T., Doran, Eric, Yong, William H., Shahin, Saba, Perez-Rosendahl, Mari, Head, Elizabeth, Green, Kim N., and Swarup, Vivek
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- 2024
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23. Development of an automatic methodology for the recognition and dimensional characterization of constant-radius sweeping features from ancient ceramic artefacts
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Di Angelo, Luca, Di Stefano, Paolo, Guardiani, Emanuele, and Morabito, Anna Eva
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- 2024
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24. Mapping small metabolite changes after traumatic brain injury using AP-MALDI MSI
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Siciliano, Angela Marika, Moro, Federico, De Simone, Giulia, Pischiutta, Francesca, Morabito, Aurelia, Pastorelli, Roberta, Brunelli, Laura, Zanier, Elisa R., and Davoli, Enrico
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- 2024
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25. How does the radio enhancement of broad absorption line quasars relate to colour and accretion rate?
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Petley, J. W., Morabito, L. K., Rankine, A. L., Richards, G. T., Thomas, N. L., Alexander, D. M., Fawcett, V. A., Rivera, G. Calistro, Prandoni, I., Best, P. N., and Kolwa, S.
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Astrophysics - Astrophysics of Galaxies ,Astrophysics - High Energy Astrophysical Phenomena - Abstract
The origin of radio emission in different populations of radio-quiet quasars is relatively unknown, but recent work has uncovered various drivers of increased radio-detection fraction. In this work, we pull together three known factors: optical colour ($g-i$), \CIV Distance (a proxy for $L/L_{Edd}$) and whether or not the quasar contains broad absorption lines (BALQSOs) which signify an outflow. We use SDSS DR14 spectra along with the LOFAR Two Metre Sky Survey Data Release 2 and find that each of these properties have an independent effect. BALQSOs are marginally more likely to be radio-detected than non-BALQSOs at similar colours and $L/L_{Edd}$, moderate reddening significantly increases the radio-detection fraction and the radio-detection increases with $L/L_{Edd}$ above a threshold for all populations. We test a widely used simple model for radio wind shock emission and calculate energetic efficiencies that would be required to reproduce the observed radio properties. We discuss interpretations of these results concerning radio-quiet quasars more generally. We suggest that radio emission in BALQSOs is connected to a different physical origin than the general quasar population since they show different radio properties independent of colour and \CIV distance., Comment: 14 pages, 8 figures, 2 tables
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- 2024
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26. Experimentally implemented dynamic optogenetic optimization of ATPase expression using knowledge-based and Gaussian-process-supported models
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Espinel-Ríos, Sebastián, Behrendt, Gerrich, Bauer, Jasmin, Morabito, Bruno, Pohlodek, Johannes, Schütze, Andrea, Findeisen, Rolf, Bettenbrock, Katja, and Klamt, Steffen
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Electrical Engineering and Systems Science - Systems and Control - Abstract
Optogenetic modulation of adenosine triphosphatase (ATPase) expression represents a novel approach to maximize bioprocess efficiency by leveraging enforced adenosine triphosphate (ATP) turnover. In this study, we experimentally implement a model-based open-loop optimization scheme for optogenetic modulation of the expression of ATPase. Increasing the intracellular concentration of ATPase, and thus the level of ATP turnover, in bioprocesses with product synthesis coupled with ATP generation, can lead to increased product formation and substrate uptake. Previous simulation studies formulated optimal control problems using dynamic constraint-based models to find optimal light inputs in fermentations with optogenetically mediated ATPase expression. However, using these models poses challenges due to resulting bilevel optimizations and complex parameterization. Here, we outline a simplified unsegregated and quasi-unstructured kinetic modeling approach that reduces the number of dynamic states and leads to single-level optimizations. The models can be augmented with Gaussian processes to compensate for model uncertainties. We implement optimal control constrained by knowledge-based and hybrid models for optogenetic ATPase expression in $\textit{Escherichia coli}$ with lactate as the main product. To do so, we genetically engineer $\textit{E. coli}$ to obtain optogenetic expression of ATPase using the CcaS/CcaR system. This represents the first experimental implementation of model-based optimization of ATPase expression in bioprocesses., Comment: 24 pages, 5 figures, journal submission
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- 2024
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27. BIN1K358R suppresses glial response to plaques in mouse model of Alzheimer's disease
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Garcia‐Agudo, Laura Fernandez, Shi, Zechuan, Smith, Ian F, Kramár, Enikö A, Tran, Katelynn, Kawauchi, Shimako, Wang, Shuling, Collins, Sherilyn, Walker, Amber, Shi, Kai‐Xuan, Neumann, Jonathan, Liang, Heidi Yahan, Da Cunha, Celia, Milinkeviciute, Giedre, Morabito, Samuel, Miyoshi, Emily, Rezaie, Narges, Gomez‐Arboledas, Angela, Arvilla, Adrian Mendoza, Ghaemi, Daryan Iman, Tenner, Andrea J, LaFerla, Frank M, Wood, Marcelo A, Mortazavi, Ali, Swarup, Vivek, MacGregor, Grant R, and Green, Kim N
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Biomedical and Clinical Sciences ,Neurosciences ,Clinical Sciences ,Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD) ,Alzheimer's Disease ,Brain Disorders ,Neurodegenerative ,Dementia ,Acquired Cognitive Impairment ,Aging ,2.1 Biological and endogenous factors ,Aetiology ,Neurological ,Mice ,Animals ,Alzheimer Disease ,Plaque ,Amyloid ,Amyloid beta-Peptides ,Neuroglia ,Mice ,Transgenic ,Disease Models ,Animal ,Alzheimer's disease ,astrocytes ,BIN1 K358R ,inflammation ,MODEL-AD ,oligodendrocytes ,MODEL‐AD ,Geriatrics ,Clinical sciences ,Biological psychology - Abstract
IntroductionThe BIN1 coding variant rs138047593 (K358R) is linked to Late-Onset Alzheimer's Disease (LOAD) via targeted exome sequencing.MethodsTo elucidate the functional consequences of this rare coding variant on brain amyloidosis and neuroinflammation, we generated BIN1K358R knock-in mice using CRISPR/Cas9 technology. These mice were subsequently bred with 5xFAD transgenic mice, which serve as a model for Alzheimer's pathology.ResultsThe presence of the BIN1K358R variant leads to increased cerebral amyloid deposition, with a dampened response of astrocytes and oligodendrocytes, but not microglia, at both the cellular and transcriptional levels. This correlates with decreased neurofilament light chain in both plasma and brain tissue. Synaptic densities are significantly increased in both wild-type and 5xFAD backgrounds homozygous for the BIN1K358R variant.DiscussionThe BIN1 K358R variant modulates amyloid pathology in 5xFAD mice, attenuates the astrocytic and oligodendrocytic responses to amyloid plaques, decreases damage markers, and elevates synaptic densities.HighlightsBIN1 rs138047593 (K358R) coding variant is associated with increased risk of LOAD. BIN1 K358R variant increases amyloid plaque load in 12-month-old 5xFAD mice. BIN1 K358R variant dampens astrocytic and oligodendrocytic response to plaques. BIN1 K358R variant decreases neuronal damage in 5xFAD mice. BIN1 K358R upregulates synaptic densities and modulates synaptic transmission.
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- 2024
28. Relapse to cocaine seeking is regulated by medial habenula NR4A2/NURR1 in mice
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Childs, Jessica E, Morabito, Samuel, Das, Sudeshna, Santelli, Caterina, Pham, Victoria, Kusche, Kelly, Vera, Vanessa Alizo, Reese, Fairlie, Campbell, Rianne R, Matheos, Dina P, Swarup, Vivek, and Wood, Marcelo A
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Biological Sciences ,Substance Misuse ,Drug Abuse (NIDA only) ,Neurosciences ,Genetics ,Brain Disorders ,Behavioral and Social Science ,Aetiology ,2.1 Biological and endogenous factors ,Good Health and Well Being ,Mice ,Animals ,Habenula ,Cocaine ,Memory ,Gene Expression Regulation ,Recurrence ,CP: Neuroscience ,Nr4a2 ,Nurr1 ,addiction ,cocaine ,learning and memory ,medial habenula ,relapse ,self-administration ,single-nucleus RNA sequencing ,substance use disorder ,transcription factor regulatory network ,Biochemistry and Cell Biology ,Medical Physiology ,Biological sciences - Abstract
Drugs of abuse can persistently change the reward circuit in ways that contribute to relapse behavior, partly via mechanisms that regulate chromatin structure and function. Nuclear orphan receptor subfamily4 groupA member2 (NR4A2, also known as NURR1) is an important effector of histone deacetylase 3 (HDAC3)-dependent mechanisms in persistent memory processes and is highly expressed in the medial habenula (MHb), a region that regulates nicotine-associated behaviors. Here, expressing the Nr4a2 dominant negative (Nurr2c) in the MHb blocks reinstatement of cocaine seeking in mice. We use single-nucleus transcriptomics to characterize the molecular cascade following Nr4a2 manipulation, revealing changes in transcriptional networks related to addiction, neuroplasticity, and GABAergic and glutamatergic signaling. The network controlled by NR4A2 is characterized using a transcription factor regulatory network inference algorithm. These results identify the MHb as a pivotal regulator of relapse behavior and demonstrate the importance of NR4A2 as a key mechanism driving the MHb component of relapse.
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- 2024
29. Towards Message Brokers for Generative AI: Survey, Challenges, and Opportunities
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Saleh, Alaa, Morabito, Roberto, Tarkoma, Sasu, Pirttikangas, Susanna, and Lovén, Lauri
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Computer Science - Distributed, Parallel, and Cluster Computing ,Computer Science - Artificial Intelligence ,Computer Science - Machine Learning ,Computer Science - Networking and Internet Architecture ,C.2.4 ,I.2.11 ,I.2.7 - Abstract
In today's digital world, Generative Artificial Intelligence (GenAI) such as Large Language Models (LLMs) is becoming increasingly prevalent, extending its reach across diverse applications. This surge in adoption has sparked a significant increase in demand for data-centric GenAI models, highlighting the necessity for robust data communication infrastructures. Central to this need are message brokers, which serve as essential channels for data transfer within various system components. This survey aims to delve into a comprehensive analysis of traditional and modern message brokers, offering a comparative study of prevalent platforms. Our study considers numerous criteria including, but not limited to, open-source availability, integrated monitoring tools, message prioritization mechanisms, capabilities for parallel processing, reliability, distribution and clustering functionalities, authentication processes, data persistence strategies, fault tolerance, and scalability. Furthermore, we explore the intrinsic constraints that the design and operation of each message broker might impose, recognizing that these limitations are crucial in understanding their real-world applicability. Finally, this study examines the enhancement of message broker mechanisms specifically for GenAI contexts, emphasizing the criticality of developing a versatile message broker framework. Such a framework would be poised for quick adaptation, catering to the dynamic and growing demands of GenAI in the foreseeable future. Through this dual-pronged approach, we intend to contribute a foundational compendium that can guide future innovations and infrastructural advancements in the realm of GenAI data communication., Comment: 20 pages, 181 references, 7 figures, 5 tables
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- 2023
30. Ubiquitous radio emission in quasars: predominant AGN origin and a connection to jets, dust and winds
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Rivera, G. Calistro, Alexander, D. M., Harrison, C. M., Fawcett, V. A., Best, P. N., Williams, W. L., Hardcastle, M. J., Rosario, D. J., Smith, D. J. B., Arnaudova, M. I., Escott, E., Gürkan, G., Kondapally, R., Miley, G., Morabito, L. K., Petley, J., Prandoni, I., Röttgering, H. J. A., and Yue, B. -H.
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Astrophysics - Astrophysics of Galaxies ,Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
We present a comprehensive study of the physical origin of radio emission in optical quasars at redshifts z < 2.5. We focus particularly on the associations between compact radio emission, dust reddening, and outflows identified in our earlier work. Leveraging the deepest low-frequency radio data available to date (LoTSS Deep DR1), we achieve radio detection fractions of up to 94%, demonstrating the virtual ubiquity of radio emission in quasars, and a continuous distribution in radio loudness. Through our analysis of radio properties, combined with spectral energy distribution modeling of multiwavelength photometry, we establish that the primary source of radio emission in quasars is the AGN, rather than star formation. Modeling the dust reddening of the accretion disk emission shows a continuous increase in radio detection in quasars as a function of the reddening parameter E(B-V), suggesting a causal link between radio emission and dust reddening. Confirming previous findings, we observe that the radio excess in red quasars is most pronounced for sources with compact radio morphologies and intermediate radio loudness. We find a significant increase in [Oiii] and Civ outflow velocities for red quasars not seen in our control sample, with particularly powerful [Oiii] winds in those around the radio-quiet/radio-loud threshold. Based on the combined characterisation of radio, reddening, and wind properties in our sample, we favor a model in which the compact radio emission observed in quasars originates in compact radio jets and their interaction with a dusty, circumnuclear environment. Our results align with the theory that jet-induced winds and shocks resulting from this interaction are the origin of the enhanced radio emission in red quasars. Further investigation of this model is crucial for advancing our understanding of quasar feedback mechanisms and their role in galaxy evolution., Comment: 11 pages, 8 Figures, submitted to A&A
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- 2023
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31. LOFAR HBA Observations of the Euclid Deep Field North (EDFN)
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Bondi, M., Scaramella, R., Zamorani, G., Ciliegi, P., Vitello, F., Arias, M., Best, P. N., Bonato, M., Botteon, A., Brienza, M., Brunetti, G., Hardcastle, M. J., Magliocchetti, M., Massaro, F., Morabito, L. K., Pentericci, L., Prandoni, I., Röttgering, H. J. A., Shimwell, T. W., Tasse, C., van Weeren, R. J., and White, G. J.
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Astrophysics - Astrophysics of Galaxies - Abstract
We present the first deep (72 hours of observations) radio image of the Euclid Deep Field North (EDFN) obtained with the LOw-Frequency ARray (LOFAR) High Band Antenna (HBA) at 144 MHz. The EDFN is the latest addition to the LOFAR Two-Metre Sky Survey (LoTSS) Deep Fields and these observations represent the first data release for this field. The observations produced a 6" resolution image with a central r.m.s. noise of $32\,\mu$Jy\,beam$^{-1}$. A catalogue of $\sim 23,000$ radio sources above a signal-to-noise ratio (SNR) threshold of 5 is extracted from the inner circular 10 deg$^2$ region. We discuss the data analysis and we provide a detailed description of how we derived the catalogue of radio sources and on the issues related to direction-dependent calibration and their effects on the final products. Finally, we derive the radio source counts at 144 MHz in the EDFN using catalogues of mock radio sources to derive the completeness correction factors. The source counts in the EDFN are consistent with those obtained from the first data release of the other LoTSS Deep Fields (ELAIS-N1, Lockman Hole and Bootes), despite the different method adopted to construct the final catalogue and to assess its completeness., Comment: accepted for publication in A&A
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- 2023
32. Biochar characteristics and Pb2+/Zn2+ sorption capacities: the role of feedstock variation
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Chafik, Y., Hassan, S. H., Lebrun, M., Sena-Velez, M., Cagnon, B., Carpin, S., Boukroute, A., Bourgerie, S., and Morabito, D.
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- 2024
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33. Improved overall survival in patients developing endocrine toxicity during treatment with nivolumab for advanced non-small cell lung cancer in a prospective study
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Albertelli, M., Rossi, G., Nazzari, E., Genova, C., Biello, F., Rijavec, E., Dal Bello, M. G., Patti, L., Tagliamento, M., Barletta, G., Morabito, P., Boschetti, M., Dotto, A., Campana, D., Ferone, D., and Grossi, F.
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- 2024
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34. Does thyroglossal duct arborization play a role in the post-surgical outcome of Sistrunk procedure in children?
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Spinelli, Claudio, Ghionzoli, Marco, Ugolini, Clara, Oreglio, Chiara, Guglielmo, Carla, Morabito, Antonino, Patrizio, Armando, Fallahi, Poupak, Ferrari, Silvia Martina, and Antonelli, Alessandro
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- 2024
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35. Efficacy of probiotic supplements in improving the symptoms of psychosis, anxiety, insomnia, and anorexia due to amphetamine and methamphetamine use: a randomized clinical trial
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Badrfam, Rahim, Zandifar, Atefeh, Hajialigol, Amirhossein, Rashidian, Maryam, Schmidt, Norman Brad, Morabito, Danielle, Qorbani, Mostafa, Shahrestanaki, Ehsan, and Mehrabani Natanzi, Mahboobeh
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- 2024
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36. IκBε deficiency accelerates disease development in chronic lymphocytic leukemia
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Bordini, Jessica, Lenzi, Chiara, Frenquelli, Michela, Morabito, Alessia, Pseftogas, Athanasios, Belloni, Daniela, Mansouri, Larry, Tsiolas, George, Perotta, Eleonora, Ranghetti, Pamela, Gandini, Francesca, Genova, Francesca, Hägerstrand, Daniel, Gavriilidis, Georgios, Keisaris, Sofoklis, Pechlivanis, Nikolaos, Davi, Frederic, Kay, Neil E., Langerak, Anton W., Pospisilova, Sarka, Scarfò, Lydia, Makris, Antonios, Psomopoulos, Fotis E., Stamatopoulos, Kostas, Rosenquist, Richard, Campanella, Alessandro, and Ghia, Paolo
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- 2024
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37. Cosmic evolution of FRI and FRII sources out to z=2.5
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de Jong, J. M. G. H. J., Röttgering, H. J. A., Kondapally, R., Mingo, B., van Weeren, R. J., Best, P. N., Morabito, L. K., Magliocchetti, M., Oonk, J. B. R., Villarrubia-Aguilar, A., and Vecchi, F. F.
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Astrophysics - Astrophysics of Galaxies - Abstract
Radio-loud active galactic nuclei (RLAGN) play an important role in the evolution of galaxies through the effects on their environment. The two major morphological classes are core-bright (FRI) and edge-bright (FRII) sources. With the LOw-Frequency ARray (LOFAR) we compare the FRI and FRII evolution down to lower flux densities and with larger samples than before with the aim to examine the cosmic space density evolution for FRIs and FRIIs by analyzing their space density evolution between L_150~10^24.5 W/Hz and L_150~10^28.5 W/Hz and up to z=2.5. We construct radio luminosity functions (RLFs) from FRI and FRII catalogues based on recent data from LOFAR at 150MHz to study the space densities as a function of radio luminosity and redshift. To partly correct for selection biases and completeness, we simulate how sources appear at a range of redshifts. We report a space density enhancement from low to high redshift for FRI and FRII sources brighter than L_150~10^27 W/Hz. This is possibly related to the higher gas availability in the earlier denser universe. The constant FRI/FRII space density ratio evolution as a function of radio luminosity and redshift in our results suggests that the jet-disruption of FRIs might be primarily caused by events occurring on scales within the host galaxy, rather than being driven by changes in the overall large-scale environment. Remaining selection biases in our results also highlight the need to resolve more sources at angular scales below 40 arcsec and therefore strengthens the motivation for the further development and automation of the calibration and imaging pipeline of LOFAR data to produce images at sub-arcsecond resolution.
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- 2023
38. Nuclear regions as seen with LOFAR international baselines: A high-resolution study of the recurrent activity
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Jurlin, N., Morganti, R., Sweijen, F., Morabito, L. K., Brienza, M., Barthel, P., and Miley, G. K.
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Astrophysics - Astrophysics of Galaxies - Abstract
Radio galaxies dominate the radio sky and are essential to the galaxy evolution puzzle. High-resolution studies of statistical samples of radio galaxies are expected to shed light on the triggering mechanisms of the AGN, alternating between the phases of activity and quiescence. In this work, we focus on the sub-arcsec radio structures in the central regions of the 35 radio galaxies over 6.6 $deg^2$ of the Lockman Hole region. These sources were previously classified as active, remnant, and candidate restarted radio galaxies using 150 MHz LOFAR observations. We examine the morphologies and study the spectral properties of their central regions to explore their evolutionary stages and revise the criteria used to select the initial sample. We use the newly available LOFAR 150 MHz image obtained using international baselines, achieving 0.38'' x 0.30'' resolution, making this the first systematic study of the nuclear regions at high resolution and low frequency. We use publicly available images from the FIRST survey at 1.4 GHz and the Karl G. Jansky VLA Sky Survey at 3 GHz to achieve our goals. In addition, for one restarted candidate we present new dedicated observations with the VLA at 3 GHz. We have found various morphologies of the central regions of the radio galaxies in our sample, some resembling miniature double-double radio galaxies. We also see the beginnings of active jets or distinct detections unrelated to the large-scale structure. Furthermore, we have found diverse radio spectra in our sample - flat, steep, or peaked between 150 MHz and 3 GHz, indicative of the different life-cycle phases. Based on these analyses, we confirm five of six previously considered restarted candidates and identify three more from the active sample, supporting previous results suggesting that the restarted phase can occur after a relatively short remnant phase (i.e. a few tens of millions of years)., Comment: Accepted for publication in A&A, 22 pages, 5 tables, 8 figures
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- 2023
39. AI-native Interconnect Framework for Integration of Large Language Model Technologies in 6G Systems
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Tarkoma, Sasu, Morabito, Roberto, and Sauvola, Jaakko
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Computer Science - Networking and Internet Architecture ,Computer Science - Artificial Intelligence - Abstract
The evolution towards 6G architecture promises a transformative shift in communication networks, with artificial intelligence (AI) playing a pivotal role. This paper delves deep into the seamless integration of Large Language Models (LLMs) and Generalized Pretrained Transformers (GPT) within 6G systems. Their ability to grasp intent, strategize, and execute intricate commands will be pivotal in redefining network functionalities and interactions. Central to this is the AI Interconnect framework, intricately woven to facilitate AI-centric operations within the network. Building on the continuously evolving current state-of-the-art, we present a new architectural perspective for the upcoming generation of mobile networks. Here, LLMs and GPTs will collaboratively take center stage alongside traditional pre-generative AI and machine learning (ML) algorithms. This union promises a novel confluence of the old and new, melding tried-and-tested methods with transformative AI technologies. Along with providing a conceptual overview of this evolution, we delve into the nuances of practical applications arising from such an integration. Through this paper, we envisage a symbiotic integration where AI becomes the cornerstone of the next-generation communication paradigm, offering insights into the structural and functional facets of an AI-native 6G network.
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- 2023
40. Device Sampling and Resource Optimization for Federated Learning in Cooperative Edge Networks
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Wang, Su, Morabito, Roberto, Hosseinalipour, Seyyedali, Chiang, Mung, and Brinton, Christopher G.
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Computer Science - Networking and Internet Architecture ,Computer Science - Distributed, Parallel, and Cluster Computing ,Computer Science - Machine Learning - Abstract
The conventional federated learning (FedL) architecture distributes machine learning (ML) across worker devices by having them train local models that are periodically aggregated by a server. FedL ignores two important characteristics of contemporary wireless networks, however: (i) the network may contain heterogeneous communication/computation resources, and (ii) there may be significant overlaps in devices' local data distributions. In this work, we develop a novel optimization methodology that jointly accounts for these factors via intelligent device sampling complemented by device-to-device (D2D) offloading. Our optimization methodology aims to select the best combination of sampled nodes and data offloading configuration to maximize FedL training accuracy while minimizing data processing and D2D communication resource consumption subject to realistic constraints on the network topology and device capabilities. Theoretical analysis of the D2D offloading subproblem leads to new FedL convergence bounds and an efficient sequential convex optimizer. Using these results, we develop a sampling methodology based on graph convolutional networks (GCNs) which learns the relationship between network attributes, sampled nodes, and D2D data offloading to maximize FedL accuracy. Through evaluation on popular datasets and real-world network measurements from our edge testbed, we find that our methodology outperforms popular device sampling methodologies from literature in terms of ML model performance, data processing overhead, and energy consumption., Comment: Published in IEEE/ACM Transactions on Networking. arXiv admin note: substantial text overlap with arXiv:2101.00787
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- 2023
41. Edge AI Inference in Heterogeneous Constrained Computing: Feasibility and Opportunities
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Morabito, Roberto, Tatipamula, Mallik, Tarkoma, Sasu, and Chiang, Mung
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Computer Science - Hardware Architecture ,Computer Science - Artificial Intelligence ,Computer Science - Distributed, Parallel, and Cluster Computing ,Computer Science - Networking and Internet Architecture - Abstract
The network edge's role in Artificial Intelligence (AI) inference processing is rapidly expanding, driven by a plethora of applications seeking computational advantages. These applications strive for data-driven efficiency, leveraging robust AI capabilities and prioritizing real-time responsiveness. However, as demand grows, so does system complexity. The proliferation of AI inference accelerators showcases innovation but also underscores challenges, particularly the varied software and hardware configurations of these devices. This diversity, while advantageous for certain tasks, introduces hurdles in device integration and coordination. In this paper, our objectives are three-fold. Firstly, we outline the requirements and components of a framework that accommodates hardware diversity. Next, we assess the impact of device heterogeneity on AI inference performance, identifying strategies to optimize outcomes without compromising service quality. Lastly, we shed light on the prevailing challenges and opportunities in this domain, offering insights for both the research community and industry stakeholders., Comment: This paper has been accepted for publication in the proceedings of the IEEE International Workshop on Computer Aided Modeling and Design of Communication Links and Networks 2023 (IEEE CAMAD 2023)
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- 2023
42. MIGHTEE: multi-wavelength counterparts in the COSMOS field
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Whittam, I. H., Prescott, M., Hale, C. L., Jarvis, M . J., Heywood, I., An, Fangxia, Glowacki, M., Maddox, N., Marchetti, L., Morabito, L. K., Adams, N. J., Bowler, R. A. A., Hatfield, P. W., Varadaraj, R. G., Collier, J., Frank, B., Taylor, A. R., Santos, M. G., Vaccari, M., Afonso, J., Ao, Y., Delhaize, J., Knowles, K., Kolwa, S., Randriamampandry, S. M., Randriamanakoto, Z., Smirnov, O., Smith, D. J. B., and White, S. V.
- Subjects
Astrophysics - Astrophysics of Galaxies - Abstract
In this paper we combine the Early Science radio continuum data from the MeerKAT International GHz Tiered Extragalactic Exploration (MIGHTEE) Survey, with optical and near-infrared data and release the cross-matched catalogues. The radio data used in this work covers $0.86$ deg$^2$ of the COSMOS field, reaches a thermal noise of $1.7$ $\mu$Jy/beam and contains $6102$ radio components. We visually inspect and cross-match the radio sample with optical and near-infrared data from the Hyper Suprime-Cam (HSC) and UltraVISTA surveys. This allows the properties of active galactic nuclei and star-forming populations of galaxies to be probed out to $z \approx 5$. Additionally, we use the likelihood ratio method to automatically cross-match the radio and optical catalogues and compare this to the visually cross-matched catalogue. We find that 94 per cent of our radio source catalogue can be matched with this method, with a reliability of $95$ per cent. We proceed to show that visual classification will still remain an essential process for the cross-matching of complex and extended radio sources. In the near future, the MIGHTEE survey will be expanded in area to cover a total of $\sim$20~deg$^2$; thus the combination of automated and visual identification will be critical. We compare redshift distribution of SFG and AGN to the SKADS and T-RECS simulations and find more AGN than predicted at $z \sim 1$., Comment: 15 pages, 15 figures. Accepted for publication in MNRAS
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- 2023
43. 1-arcsecond imaging of ELAIS-N1 field at 144MHz using the LoTSS survey with international LOFAR telescope
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Ye, Haoyang, Sweijen, Frits, van Weeren, Reinout, Williams, Wendy, de Jong, Jurjen, Morabito, Leah K., Rottgering, Huub, Shimwell, T. W., Best, P. N., Bondi, Marco, Brüggen, Marcus, de Gasperin, Francesco, and Tasse, C.
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Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
We present the first wide area (2.5 x 2.5 deg^2) LOFAR High Band Antenna image at a resolution of 1.2'' x 2'' with a median noise of approximately 80 microJy per beam. It was made from an 8-hour International LOFAR Telescope (ILT) observation of the ELAIS-N1 field at frequencies ranging from 120 to 168 MHz with the most up-to-date ILT imaging methods. This intermediate resolution falls between the highest possible resolution (0.3'') achievable by using all International LOFAR Telescope (ILT) baselines and the standard 6-arcsecond resolution in the LoTSS (LOFAR Two-meter Sky Survey) image products utilising the LOFAR Dutch baselines only. This is the first demonstration of the feasibility of imaging using the ILT at a resolution of around 1'', which provides unique information on source morphology at scales that fall below the surface brightness limits at higher resolutions. The total calibration and imaging computational time is approximately 52,000 core hours, nearly 5 times more than required to produce a 6'' resolution image. We also present a radio source catalogue containing 2263 sources detected over the 2.5 x 2.5 deg^2 image of the ELAIS-N1 field, with a peak intensity threshold of 5.5 sigma. The catalogue has been cross-matched with the LoTSS deep ELAIS-N1 field radio catalogue, and its flux density and positional accuracy have been investigated and corrected accordingly. We find that approximately 80% of sources which we expect to be detectable based on their peak brightness in the LoTSS 6'' resolution image are detected in this image, which is approximately a factor of two higher than for 0.3'' resolution imaging in the Lockman Hole, implying there is a wealth of information on these intermediate scales., Comment: 20 pages, 19 figures, revised manuscript submitted to A&A
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- 2023
44. How Can AI be Distributed in the Computing Continuum? Introducing the Neural Pub/Sub Paradigm
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Lovén, Lauri, Morabito, Roberto, Kumar, Abhishek, Pirttikangas, Susanna, Riekki, Jukka, and Tarkoma, Sasu
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Computer Science - Networking and Internet Architecture - Abstract
This paper proposes the neural publish/subscribe paradigm, a novel approach to orchestrating AI workflows in large-scale distributed AI systems in the computing continuum. Traditional centralized broker methodologies are increasingly struggling with managing the data surge resulting from the proliferation of 5G systems, connected devices, and ultra-reliable applications. Moreover, the advent of AI-powered applications, particularly those leveraging advanced neural network architectures, necessitates a new approach to orchestrate and schedule AI processes within the computing continuum. In response, the neural pub/sub paradigm aims to overcome these limitations by efficiently managing training, fine-tuning and inference workflows, improving distributed computation, facilitating dynamic resource allocation, and enhancing system resilience across the computing continuum. We explore this new paradigm through various design patterns, use cases, and discuss open research questions for further exploration.
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- 2023
45. Association between PD-1 single nucleotide gene variants and the risk of metastatic melanoma
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Boutros, Andrea, Carosio, Roberta, Campanella, Dalila, Banelli, Barbara, Morabito, Anna, Pistillo, Maria Pia, Croce, Elena, Queirolo, Paola, Tanda, Enrica Teresa, Raposio, Edoardo, Fontana, Vincenzo, and Spagnolo, Francesco
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- 2024
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46. Youth Mental Health Crisis Response: A Multiple Methods Study to Map Resources and Identify Facilitators and Barriers to Service Access
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Astraea Augsberger, Margaret Carroll, Riana C. Howard, Gloria Ng, Thomas Maldonado-Reis, Andria Amador, Melissa S. Morabito, and Jennifer Greif Green
- Abstract
Youth mental health crises in the USA increased dramatically during the COVID-19 pandemic. Schools are uniquely positioned to address the growing mental health needs of youth by connecting them with mental health services; however, they are often under-resourced to provide these services. This study used community resource mapping to identify the existence, distribution, and types of youth mental health crisis services available in the Boston area. Semi-structured interviews with school and community providers were conducted to examine the facilitators and barriers to youth mental health crisis service access. Findings show that while 23 programs were identified in Boston, there were gaps in terms of service availability by neighborhood, language accessibility, and type of crisis services provided. Thematic analysis of the qualitative interviews identified attitudinal and structural barriers to service utilization, including family stigma related to mental health diagnosis and services, resource accessibility and COVID-19 impacts, and the need for additional training and support for families and school-based staff. Findings demonstrate the need for cross-discipline school and community collaboration and culturally responsive mental health education and promotion.
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- 2024
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47. Comparative analysis of mathematical formulations for the two-dimensional guillotine cutting problem
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Becker, Henrique, Martin, Mateus, Araujo, Olinto, Buriol, Luciana S., and Morabito, Reinaldo
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Mathematics - Optimization and Control ,Computer Science - Discrete Mathematics ,Computer Science - Data Structures and Algorithms ,Computer Science - Mathematical Software ,G.2.0 - Abstract
About ten years ago, a paper proposed the first integer linear programming formulation for the constrained two-dimensional guillotine cutting problem (with unlimited cutting stages). Since, six other formulations followed, five of them in the last two years. This spike of interest gave no opportunity for a comprehensive comparison between the formulations. We review each formulation and compare their empirical results over instance datasets of the literature. We adapt most formulations to allow for piece rotation. The possibility of adaptation was already predicted but not realized by the prior work. The results show the dominance of pseudo-polynomial formulations until the point instances become intractable by them, while more compact formulations keep achieving good primal solutions. Our study also reveals a small but consistent advantage of the Gurobi solver over the CPLEX solver in our context; that the choice of solver hardly benefits one formulation over another; and a mistake in the generation of the T instances, which should have the same optima with or without guillotine cuts. Our study also proposes hybridising the most recent formulation with a prior formulation for a restricted version of the problem. The hybridisations show a reduction of about 20% of the branch-and-bound time thanks to the symmetries broken by the hybridisation., Comment: 23 pages, 7 tables, 3 figures
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- 2023
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48. Sub-arcsecond resolution imaging of M 51 with the International LOFAR Telescope
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Venkattu, Deepika, Lundqvist, Peter, Pérez-Torres, Miguel, Morabito, Leah, Moldón, Javier, Conway, John, Chandra, Poonam, and Tasse, Cyril
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Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Astrophysics of Galaxies - Abstract
We present an International LOFAR Telescope sub-arcsecond resolution image of the nearby galaxy M 51 with a beam size of 0.436" x 0.366" and rms of 46 $\mu$Jy. We compare this image with an European VLBI Network study of M 51, and discuss the supernovae in this galaxy, which have not yet been probed at these low radio frequencies. We find a flux density of 0.97 mJy for SN 2011dh in the ILT image, which is about five times smaller than the flux density reported by the LOFAR Twometre Sky Survey at 6" resolution using the same dataset without the international stations. This difference makes evident the need for LOFAR international baselines to reliably obtain flux density measurements of compact objects in nearby galaxies. Our LOFAR flux density measurement of SN 2011dh directly translates into fitting the radio light curves for the supernova and constraining massloss rates of progenitor star. We do not detect two other supernovae in the same galaxy, SN 1994I and SN 2005cs, and our observations place limits on the evolution of both supernovae at radio wavelengths. We also discuss the radio emission from the centre of M 51, in which we detect the Active Galactic Nucleus and other parts of the nuclear emission in the galaxy, and a possible detection of Component N. We discuss a few other sources, including the detection of a High mass X-ray Binary not detected by LoTSS, but with a flux density in the ILT image that matches well with higher frequency catalogues., Comment: Accepted for publication in the Astrophysical Journal. 16 pages, 5 figures
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- 2023
49. Cosmic evolution of radio-AGN feedback: confronting models with data
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Kondapally, R., Best, P. N., Raouf, M., Thomas, N. L., Davé, R., Shabala, S. S., Röttgering, H. J. A., Hardcastle, M. J., Bonato, M., Cochrane, R. K., Małek, K., Morabito, L. K., Prandoni, I., and Smith, D. J. B.
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Astrophysics - Astrophysics of Galaxies ,Astrophysics - High Energy Astrophysical Phenomena - Abstract
Radio-mode feedback is a key ingredient in galaxy formation and evolution models, required to reproduce the observed properties of massive galaxies in the local Universe. We study the cosmic evolution of radio-AGN feedback out to $z\sim2.5$ using a sample of 9485 radio-excess AGN. We combine the evolving radio luminosity functions with a radio luminosity scaling relationship to estimate AGN jet kinetic powers and derive the cosmic evolution of the kinetic luminosity density, $\Omega_{\rm{kin}}$ (i.e. the volume-averaged heating output). Compared to all radio-AGN, low-excitation radio galaxies (LERGs) dominate the feedback activity out to $z\sim2.5$, with both these populations showing a constant heating output of $\Omega_{\rm{kin}} \approx 4-5 \times 10^{32}\,\rm{W\,Mpc^{-3}}$ across $0.5 < z < 2.5$. We compare our observations to predictions from semi-analytical and hydrodynamical simulations, which broadly match the observed evolution in $\Omega_{\rm{kin}}$, although their absolute normalisation varies. Comparison to the Semi-Analytic Galaxy Evolution (SAGE) model suggests that radio-AGN may provide sufficient heating to offset radiative cooling losses, providing evidence for a self-regulated AGN feedback cycle. We integrate the kinetic luminosity density across cosmic time to obtain the kinetic energy density output from AGN jets throughout cosmic history to be $\sim 10^{50}\,\rm{J\,Mpc^{-3}}$. Compared to AGN winds, the kinetic energy density from AGN jets dominates the energy budget at $z \lesssim 2$; this suggests that AGN jets play an important role in AGN feedback across most of cosmic history., Comment: 15 pages, 6 figures, accepted for publication in MNRAS
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- 2023
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50. Targeting heterochromatin eliminates chronic myelomonocytic leukemia malignant stem cells through reactivation of retroelements and immune pathways
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Hidaoui, Donia, Porquet, Audrey, Chelbi, Rabie, Bohm, Mathieu, Polyzou, Aikaterini, Alcazer, Vincent, Depil, Stéphane, Imanci, Aygun, Morabito, Margot, Renneville, Aline, Selimoglu-Buet, Dorothée, Thépot, Sylvain, Itzykson, Raphael, Laplane, Lucie, Droin, Nathalie, Trompouki, Eirini, Elvira-Matelot, Emilie, Solary, Eric, and Porteu, Françoise
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- 2024
- Full Text
- View/download PDF
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