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1,429 results on '"Moradi, S"'

2. Preparing and Characterizing Chitosan Nanoparticles Containing Hemiscorpius lepturus Scorpion Venom as an Antigen Delivery System

Author

Mohammadpour Dounighi, N., Damavandi, M., Zolfagharian, H., and Moradi, S.

Subjects
Chitosan, Nanoparticle, Venom, Ionic gelation, Veterinary medicine, SF600-1100
Abstract

In recent years, chitosan nanoparticles have been studied widely for protein delivery. In this study, Hemiscorpius lepturus (HL) venom was encapsulated in chitosan nanoparticles. The aim of the present work was to carry out a systematic study for preparing biocompatible and biodegradable nanoparticles for loading HL scorpion venom and to evaluate their potential as an antigen delivery system. In this study, HL venom loaded chitosan nanoparticles fabricated by ionic gelation of chitosan and tripolyphosphate and the factors which may be influenced in the preparation of nanoparticles were analyzed. Also, their physicochemical properties and in vitro release behavior were studied. The optimum encapsulation efficiency and capacity were observed when the chitosan concentration and HL venom were 2mg/ml and 500µg/ml, respectively. The HL venom loaded nanoparticles were in the size range of 130-160nm (polydispersity index values of 0.423) and exhibited the positive zeta potential. Transmission electron microscope imaging showed spherical and smooth surface of nanoparticles. The profiles of the release exhibited a burst releases about 50% in the first 4 hr and then slowed down at a constant rate. The obtained results suggested that the chitosan nanoparticles prepared in this work had the potential for antigen delivery.

Published
2012

4. Phase and amplitude evolution in the network of triadic interactions of the Hasegawa-Wakatani system

Author

Gürcan, Ö. D., Anderson, J., Moradi, S., Biancalani, A., and Morel, P.

Subjects
Nonlinear Sciences - Chaotic Dynamics, Physics - Fluid Dynamics, Physics - Plasma Physics
Abstract

Hasegawa-Wakatani system, commonly used as a toy model of dissipative drift waves in fusion devices is revisited with considerations of phase and amplitude dynamics of its triadic interactions. It is observed that a single resonant triad can saturate via three way phase locking where the phase differences between dominant modes converge to constant values as individual phases increase in time. This allows the system to have approximately constant amplitude solutions. Non-resonant triads show similar behavior only when one of its legs is a zonal wave number. However when an additional triad, which is a reflection of the original one with respect to the $y$ axis is included, the behavior of the resulting triad pair is shown to be more complex. In particular, it is found that triads involving small radial wave numbers (large scale zonal flows) end up transferring their energy to the subdominant mode which keeps growing exponentially, while those involving larger radial wave numbers (small scale zonal flows) tend to find steady chaotic or limit cycle states (or decay to zero). In order to study the dynamics in a connected network of triads, a network formulation is considered including a pump mode, and a number of zonal and non-zonal subdominant modes as a dynamical system. It was observed that the zonal modes become clearly dominant only when a large number of triads are connected. When the zonal flow becomes dominant as a 'collective mean field', individual interactions between modes become less important, which is consistent with the inhomogeneous wave-kinetic picture. Finally, the results of direct numerical simulation is discussed for the same parameters and various forms of the order parameter are computed. It is observed that nonlinear phase dynamics results in a flattening of the large scale phase velocity as a function of scale in direct numerical simulations.

Published
2022
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11. P.067 Pharmacological prophylaxis for chronic migraine: A systematic review and network meta-analysis of randomized controlled trials

Author

Khalili, M, primary, Liaghatdar, A, additional, Mahdian, F, additional, Levit, T, additional, Moradi, S, additional, Hedayati, E, additional, Torabiardakani, K, additional, Ahmadi, F, additional, Khademioore, S, additional, Sofi-Mahmudi, A, additional, Atkin-Jones, T, additional, Patil, V, additional, Mirzayeh Fashami, F, additional, Mehmandoost, S, additional, Sharma, S, additional, Fereshtehnejad, M, additional, Busse, J, additional, and Sadeghirad, B, additional

Published
2024
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14. Job Burnout in Public and Special School Teachers

Author

Hemati Alamdarloo G. and Moradi S.

Subjects
job burnout, teachers, public schools, special schools, Medicine
Abstract

The purpose of this research was to compare job burnout among public and special school teachers. The statistical population of this research consisted of all public and special school teachers in Jahrom, Iran. Of these teachers, 84 (42 public school teachers and 42 special school teachers) were selected as the study sample. Special school teachers and public school teachers were chosen using convenience sampling and multistage random sampling methods, respectively. The Maslach Burnout Inventory was used to measure job burnout. The collected data were analyzed by multivariate analysis of variance (MANOVA). The results revealed that job burnout subscales (except for the Low sense of personal accomplishment), were higher among the special school teachers compared to those of the public school teachers (p

Published
2021
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18. Reliability Analysis of a Drilling Bit Penetration Model in Oil and Gas Wells: A Case Study.

Author

Jalakani, R., Tabatabaee Moradi, S. S., and Morenov, V.

Subjects
GAS wells, DRILLING & boring, MATHEMATICAL models, PARAMETER estimation, DATA analysis
Abstract

Rate of drilling bit penetration into the subsurface formations, referred to as rate of penetration (ROP), is considered as the main optimization parameter in the drilling operation. ROP optimization results in a faster and cheaper operation. The rate of bit penetration depends on several factors, including but not limited to rock properties, fluid characteristics and drilling operational parameters. Due to the diversity of affecting parameters, prediction of rate of penetration is a challenging task. There are various mathematical relations in the literature to estimate ROP. However, these relations are developed based on specific conditions, where data from a field or experimental tests are used to develop the relations. In this work, drilling data of three wells from one onshore oil fields are gathered and then the performances of some common ROP models are investigated. Results show that the simplified Bourgoyne and Young model can accurately predict the ROP in the mentioned field, which makes the model applicable for planning of the new offset wells in the future. It should be noted that the model requires fewer input data, which makes it more applicable. The results show the average R2 coefficient for the model is 0.91, which is higher than other models. The results confirmed the applicability of the model. [ABSTRACT FROM AUTHOR]

Published
2024
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19. Harnessing disulfide and transesterification bond exchange reactions for recyclable and reprocessable 3D-printed vitrimers

Author

Universitat Rovira i Virgili, Vilanova-Pérez, A; Moradi, S; Konuray, O; Ramis, X; Roig, A; Fernández-Francos, X, Universitat Rovira i Virgili, and Vilanova-Pérez, A; Moradi, S; Konuray, O; Ramis, X; Roig, A; Fernández-Francos, X

Abstract

Two new vitrimeric materials have been studied for potential additive manufacturing applications such as 3Dprinting. A monomer containing disulfide bonds and beta-hydroxyesters was easily synthesized from two lowcost and commercially available reagents. Another disulfide-containing monomer was synthesized for comparison purposes. Materials were prepared through a UV-light radical polymerization of methacrylates. The addition of two reactive diluents such as poly(ethylene glycol) methyl ether methacrylate (PEGMA) and ethylene glycol phenyl ether methacrylate (EGPMA) was necessary to achieve a suitable viscosity for the curing as well as for their printability. The curing process was controlled by FTIR. Thermomechanical properties were investigated by means of DMTA analysis revealing near-ambient T-g values. Stress relaxation tests revealed that both materials were capable to relax the 63% of the initial stress in less than 10 min at 110( degrees)C. The recyclability of the materials was achieved, and the mechanical and thermomechanical properties of the recycled samples were compared to the virgin ones revealing a great recovery of the initial properties. Finally, Digital Light Processing (DLP) technique was used to print complex structures with high resolution highlighting the great potential of these vitrimeric materials in 3D printing.

Published
2024

20. Core micro-instability analysis of JET hybrid and baseline discharges with carbon wall

Author

Moradi, S., Pusztai, I., Voitsekhovitch, I., Garzotti, L., Bourdelle, C., Pueschel, M. J., Lupelli, I., Romanelli, M., and contributors, the JET-EFDA

Subjects
Physics - Plasma Physics
Abstract

The core micro-instability characteristics of hybrid and baseline plasmas in a selected set of JET plasmas with carbon wall are investigated through local linear and non-linear and global linear gyro-kinetic simulations with the GYRO code [J. Candy and E. Belli, General Atomics Report GA-A26818 (2011)]. In particular, we study the role of plasma pressure on the micro-instabilities, and scan the parameter space for the important plasma parameters responsible for the onset and stabilization of the modes under experimental conditions. We find that a good core confinement due to strong stabilization of the micro-turbulence driven transport can be expected in the hybrid plasmas due to the stabilizing effect of the fast ion pressure that is more effective at the low magnetic shear of the hybrid discharges. While parallel velocity gradient destabilization is important for the inner core, at outer radii the hybrid plasmas may benefit from a strong quench of the turbulence transport by $\mathbf{E}\times\mathbf{B}$ rotation shear., Comment: accepted for publication in Nuclear Fusion

Published
2014
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23. Thin films thickness Measurement by the conductivity theory in the framework of born approximation

Author

Jannesar, M., Jafari, G. R., Farahani, S. Vasheghani, and Moradi, S.

Subjects
Condensed Matter - Mesoscale and Nanoscale Physics
Abstract

When the thickness of the layer is smaller than the electrons mean free path, the morphology affects the conductivity directly based on the layer thickness. This issue provides basis in order to estimate the thickness of the layer by understanding the morphology and the value of the conductivity. This method is an inverse approach on thickness estimation and is applied to various samples. The comparison of the results with other thickness estimations shows good consistency. The benefits of this approach is that the only parameter that needs to be measured is the conductivity, which is quite trivial. Despite the simplicity of this approach, its results would prove adequate to study both the material properties and the morphology of the layer. In addition, the possibility of repeating the measurements on thickness for AC currents with various frequencies enables averaging the measurements in order to obtain the most precise results., Comment: 11 pages, 4 figures

Published
2013
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24. Impurity transport in trapped electron mode driven turbulence

Author

Mollén, A., Pusztai, I., Fülöp, T., and Moradi, S.

Subjects
Physics - Plasma Physics
Abstract

Trapped electron mode turbulence is studied by gyrokinetic simulations with the GYRO code and an analytical model including the effect of a poloidally varying electrostatic potential. Its impact on radial transport of high-Z trace impurities close to the core is thoroughly investigated and the dependence of the zero-flux impurity density gradient (peaking factor) on local plasma parameters is presented. Parameters such as ion-to-electron temperature ratio, electron temperature gradient and main species density gradient mainly affect the impurity peaking through their impact on mode characteristics. The poloidal asymmetry, the safety factor and magnetic shear have the strongest effect on impurity peaking, and it is shown that under certain scenarios where trapped electron modes are dominant, core accumulation of high-Z impurities can be avoided. We demonstrate that accounting for the momentum conservation property of the impurity-impurity collision operator can be important for an accurate evaluation of the impurity peaking factor., Comment: 30 pages, 10 figures

Published
2013
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25. Micro-tearing modes in spherical and conventional tokamaks

Author

Moradi, S., Pusztai, I., Guttenfelder, W., Fülöp, T., and Mollén, A.

Subjects
Physics - Plasma Physics
Abstract

The onset and characteristics of Micro-Tearing Modes (MTM) in the core of spherical (NSTX) and conventional tokamaks (ASDEX-UG and JET) are studied through local linear gyrokinetic simulations with gyro [J. Candy and E. Belli, General Atomics Report GA-A26818 (2011)]. For experimentally relevant core plasma parameters in the NSTX and ASDEX-UG tokamaks, in agreement with previous works, we find MTMs as the dominant linear instability. Also, for JET-like core parameters considered in our study an MTM is found as the most unstable mode. In all these plasmas, finite collisionality is needed for MTMs to become unstable and the electron temperature gradient is found to be the fundamental drive. However, a significant difference is observed in the dependence of linear growth rate of MTMs on electron temperature gradient. While it varies weakly and non-monotonically in JET and ASDEX-UG plasmas, in NSTX it increases with the electron temperature gradient., Comment: 18 pages, 9 figures

Published
2013
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26. Possible mechanism responsible for observed impurity outward flow under radio frequency heating

Author

Moradi, S., Fülöp, T., Mollén, A., and Pusztai, I.

Subjects
Physics - Plasma Physics
Abstract

The effect of poloidal asymmetry of impurities on impurity transport driven by electrostatic turbulence in tokamak plasmas is analyzed. It is found that in the presence of in-out asymmetric impurity populations the zero-flux impurity density gradient (the so-called peaking factor) is significantly reduced. A sign change in the impurity flux may occur if the asymmetry is sufficiently large. This may be a contributing reason for the observed outward convection of impurities in the presence of radio frequency heating. The effect of in-out asymmetry is most significant in regions with low temperature gradients. In the trapped electron mode dominated case also an up-down asymmetry can lead to a sign change in the peaking factor from positive to negative. The effect of ion parallel compressibility on the peaking factor is significant, and leads to positive peaking factors in regions with high temperature gradients, even in the presence of in-out asymmetry., Comment: 19 pages, 14 figures

Published
2011
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27. A theory of non-local linear drift wave transport

Author

Moradi, S., Anderson, J., and Weyssow, B.

Subjects
Physics - Plasma Physics, Mathematical Physics
Abstract

Transport events in turbulent tokamak plasmas often exhibit non-local or non-diffusive action at a distance features that so far have eluded a conclusive theoretical description. In this paper a theory of non-local transport is investigated through a Fokker-Planck equation with fractional velocity derivatives. A dispersion relation for density gradient driven linear drift modes is derived including the effects of the fractional velocity derivative in the Fokker-Planck equation. It is found that a small deviation (a few percent) from the Maxwellian distribution function alters the dispersion relation such that the growth rates are substantially increased and thereby may cause enhanced levels of transport., Comment: 22 pages, 2 figures. Manuscript submitted to Physics of Plasmas

Published
2011
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28. Entanglement of Dirac fields in an expanding spacetime

Author

Fuentes, I., Mann, R. B., Martin-Martinez, E., and Moradi, S.

Subjects
Quantum Physics, General Relativity and Quantum Cosmology
Abstract

We study the entanglement generated between Dirac modes in a 2-dimensional conformally flat Robertson-Walker universe. We find radical qualitative differences between the bosonic and fermionic entanglement generated by the expansion. The particular way in which fermionic fields get entangled encodes more information about the underlying space-time than the bosonic case, thereby allowing us to reconstruct the parameters of the history of the expansion. This highlights the importance of bosonic/fermionic statistics to account for relativistic effects on the entanglement of quantum fields., Comment: revtex4, 7 figures, I.F. previously published as Fuentes-Guridi and Fuentes-Schuller. Journal reference updated

Published
2010
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29. A Fixed-Point Theorem For Mapping Satisfying a General Contractive Condition Of Integral Type Depended an Another Function

Author

Moradi, S. and Beiranvand, A.

Subjects
Mathematics - Functional Analysis, 46J10, 46J15, 47H10
Abstract

In this paper, we study the existence of fixed points for mappings defined on complete metric space (X, d) satisfying a general contractive inequality of integral type depended on another function. This conditions is analogous of Banach conditions and Branciari Theorem., Comment: 9 pages

Published
2009

30. Two Fixed-Point Theorems For Special Mappings

Author

Beiranvand, A., Moradi, S., Omid, M., and Pazandeh, H.

Subjects
Mathematics - Functional Analysis, 46J10, 46J15, 47H10
Abstract

In this paper, we study the existence of fixed points for mappings defined on complete (compact) metric space (X, d) satisfying a general contractive (contraction) inequality depended on another function. These conditions are analogous to Banach conditions., Comment: 6 pages

Published
2009

33. Discrete Symmetries for Spinor Field in de Sitter Space

Author

Moradi, S., Rouhani, S., and Takook, M. V.

Subjects
General Relativity and Quantum Cosmology
Abstract

Discrete symmetries, parity, time reversal, antipodal, and charge conjugation transformations for spinor field in de Sitter space, are presented in the ambient space notation, i.e. in a coordinate independent way. The PT and PCT transformations are also discussed in this notation. The five-current density is studied and their transformation under the discrete symmetries is discussed., Comment: 13 pages, LaTeX; appendices added

Published
2005
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39. On Relating to the Unconscious: An Outlook.

Author

Moradi, S. Robert

Subjects
*ARTIFICIAL intelligence, *CHATGPT, *GRADUATION (Education), *PROFESSIONS
Abstract

This article, initially crafted for a keynote at the Reiss-Davis Graduate Center's graduation in Los Angeles, was later submitted to Psychological Perspectives, aiming to spark dialogue on the unconscious psyche's role in clinical practice. Upon learning about the capabilities of artificial intelligence (AI), I turned to ChatGPT-4 for an edit, and the results were nothing short of surprising. Psychological Perspectives has chosen to display my original piece alongside the AI-edited version, highlighting the potential of technology in our field. In addition to sharing my reactions to the AI revisions—both consciously and through an incubated dream—I had the AI program craft an abstract and review, both found below. Nonetheless, my primary goal remains: to foster discussions on the unconscious psyche in our profession using this dual presentation as a catalyst for broader debates about AI's place in our work. [ABSTRACT FROM AUTHOR]

Published
2024
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40. A Review on Glycerol-Based Drilling Fluids and Glycerine as a Drilling Fluid Additive.

Author

Momeni, A., Moradi, S. Sh. Tabatabaee, and Nejad, S. A. Tabatabaei

Subjects
DRILLING fluids, DRILLING muds, PROPERTIES of fluids, GAS reservoirs, PETROLEUM in submerged lands, COALBED methane
Abstract

Copyright of Rudarsko-Geolosko-Naftni Zbornik is the property of Faculty of Mining, Geology & Petroleum Engineering and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2024
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41. Highly selective sol-gel derived optical sensor using 2,6-dichlorophenolindophenol for the sensitive determination of aqueous iron(III).

Author

Yari, Abdollah, Shiravandi, A., and Moradi, S.

Subjects
OPTICAL sensors, IRON, DRINKING water, SOL-gel processes, DETECTION limit, CHEMORECEPTORS
Abstract

The design and fabrication of a novel high-sensitivity optical sensor is reported that is highly selective for aqueous Fe3+. 2,6-Dichlorophenolindophenol is embedded in a film by the sol-gel method, which plays the role of the sensing element for Fe3+. The sensor selectively determined Fe(III) ion across a wide dynamic range from 1.70 × 10−8 to 3.31 × 10−3 M at pH 4.4 with a detection limit of 1.22 × 10−8 M. The response of the sensor is fully reversible and is selective for Fe3+. The microporous nature of the stable sol-gel coating provides a unique optical membrane that gives reliable measurements. In addition, the sensor exhibits a long lifetime, long-term stability, and good repeatability. This sensor was successfully used to determine Fe3+ in tap and river water and showed satisfactory results. [ABSTRACT FROM AUTHOR]

Published
2023
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42. Enhanced performance in fusion plasmas through turbulence suppression by megaelectronvolt ions

Author

Mazzi, S., Garcia, J., Zarzoso, D., Kazakov, Y., Ongena, J., Dreval, M., Nocente, M., Stancar, Z., Szepesi, G., Eriksson, J., Sahlberg, A., Benkadda, S., Abid, N., Abraham, K., Abreu, P., Adabonyan, O., Adrich, P., Afanasev, V., Afzal, M., Ahlgren, T., Aho-Mantila, L., Aiba, N., Airila, M., Akhtar, M., Albanese, R., Alderson-Martin, M., Alegre, D., Aleiferis, S., Aleksa, A., Alekseev, A., Alessi, E., Aleynikov, P., Algualcil, J., Ali, M., Allinson, M., Alper, B., Alves, E., Ambrosino, G., Ambrosino, R., Amosov, V., Andersson Sunden, E., Andrew, P., Angelini, B., Angioni, C., Antoniou, I., Appel, L., Appelbee, C., Aria, S., Ariola, M., Artaserse, G., Arter, W., Artigues, V., Asakura, N., Ash, A., Ashikawa, N., Aslanyan, V., Astrain, M., Asztalos, O., Auld, D., Auriemma, F., Austin, Y., Avotina, L., Aymerich, E., Baciero, A., Bairaktaris, F., Balbin, J., Balbinot, L., Balboa, I., Balden, M., Balshaw, C., Balshaw, N., Bandaru, V., Banks, J., Baranov, Y., Barcellona, C., Barnard, A., Barnard, M., Barnsley, R., Barth, A., Baruzzo, M., Barwell, S., Bassan, M., Batista, A., Batistoni, P., Baumane, L., Bauvir, B., Baylor, L., Beaumont, P., Beckett, D., Begolli, A., Beidler, M., Bekris, N., Beldishevski, M., Belli, E., Belli, F., Belonohy, E., Ben Yaala, M., Benayas, J., Bentley, J., Bergsaker, H., Bernardo, J., Bernert, M., Berry, M., Bertalot, L., Betar, H., Beurskens, M., Bickerton, S., Bieg, B., Bielecki, J., Bierwage, A., Biewer, T., Bilato, R., Bílkova, P., Birkenmeier, G., Bishop, H., Bizarro, J., Blackburn, J., Blanchard, P., Blatchford, P., Bobkov, V., Boboc, A., Bohm, P., Bohm, T., Bolshakova, I., Bolzonella, T., Bonanomi, N., Bonfiglio, D., Bonnin, X., Bonofiglo, P., Boocock, S., Booth, A., Booth, J., Borba, D., Borodin, D., Borodkina, I., Boulbe, C., Bourdelle, C., Bowden, M., Boyd, K., Bozicevic Mihalic, I., Bradnam, S., Braic, V., Brandt, L., Bravanec, R., Breizman, B., Brett, A., Brezinsek, S., Brix, M., Bromley, K., Brown, B., Brunetti, D., Buckingham, R., Buckley, M., Budny, R., Buermans, J., Bufferand, H., Buratti, P., Burgess, A., Buscarino, A., Busse, A., Butcher, D., Cal, E., Calabro, G., Calacci, L., Calado, R., Camenen, Y., Canal, G., Cannas, B., Cappelli, M., Carcangiu, S., Card, P., Cardinali, A., Carman, P., Carnevale, D., Carr, M., Carralero, D., Carraro, L., Carvalho, I., Carvalho, P., Casiraghi, I., Casson, F., Castaldo, C., Catalan, J., Catarino, N., Causa, F., Cavedon, M., Cecconello, M., Challis, C., Chamberlain, B., Chang, C., Chankin, A., Chapman, B., Chernyshova, M., Chiariello, A., Chmielewski, P., Chomiczewska, A., Chone, L., Ciraolo, G., Ciric, D., Citrin, J., Ciupinski, t., Clark, M., Clarkson, R., Clements, C., Cleverly, M., Coad, J., Coates, P., Cobalt, A., Coccorese, V., Coelho, R., Coenen, J., Coffey, I., Colangeli, A., Colas, L., Collins, C., Collins, J., Collins, S., Conka, D., Conroy, S., Conway, B., Conway, N., Coombs, D., Cooper, P., Cooper, S., Corradino, C., Corrigan, G., Coster, D., Cox, P., Craciunescu, T., Cramp, S., Crapper, C., Craven, D., Craven, R., Crialesi Esposito, M., Croci, G., Croft, D., Croitoru, A., Crombe, K., Cronin, T., Cruz, N., Crystal, C., Cseh, G., Cufar, A., Cullen, A., Curuia, M., Czarski, T., Dabirikhah, H., Dal Molin, A., Dale, E., Dalgliesh, P., Dalley, S., Dankowski, J., David, P., Davies, A., Davies, S., Davis, G., Dawson, K., Dawson, S., Day, I., De Bock, M., De Temmerman, G., De Tommasi, G., Deakin, K., Deane, J., Dejarnac, R., Del Sarto, D., Delabie, E., Del-Castillo-Negrete, D., Dempsey, A., Dendy, R., Devynck, P., Di Siena, A., Di Troia, C., Dickson, T., Dinca, P., Dittmar, T., Dobrashian, J., Doerner, R., Donne, A., Dorling, S., Dormido-Canto, S., Douai, D., Dowson, S., Doyle, R., Drewelow, P., Drews, P., Drummond, G., Duckworth, P., Dudding, H., Dumont, R., Dumortier, P., Dunai, D., Dunatov, T., Dunne, M., Duran, I., Durodie, F., Dux, R., Dvornova, A., Eastham, R., Edwards, J., Eich, T., Eichorn, A., Eidietis, N., Eksaeva, A., Haroun, H., Ellwood, G., Elsmore, C., Embreus, O., Emery, S., Ericsson, G., Eriksson, B., Eriksson, F., Eriksson, L., Ertmer, S., Esquembri, S., Esquisabel, A., Estrada, T., Evans, G., Evans, S., Fable, E., Fagan, D., Faitsch, M., Falessi, M., Fanni, A., Farahani, A., Farquhar, I., Fasoli, A., Faugeras, B., Fazinie, S., Felici, F., Felton, R., Fernandes, A., Fernandes, H., Ferrand, J., Ferreira, D., Ferreira, J., Ferro, G., Fessey, J., Ficker, O., Field, A., Figueiredo, A., Figueiredo, J., Fil, A., Fil, N., Finburg, P., Fiorucci, D., Fischer, U., Fishpool, G., Fittill, L., Fitzgerald, M., Flammini, D., Flanagan, J., Flinders, K., Foley, S., Fonnesu, N., Fontana, M., Fontdecaba, J., Forbes, S., Formisano, A., Fornal, T., Fortuna, L., Fortuna-Zalesna, E., Fortune, M., Fowler, C., Fransson, E., Frassinetti, L., Freisinger, M., Fresa, R., Fridstrom, R., Frigione, D., Fülop, T., Furseman, M., Fusco, V., Futatani, S., Gadariya, D., Gal, K., Galassi, D., Gafezka, K., Galeani, S., Gallart, D., Galvao, R., Gao, Y., Garcia-Munoz, M., Gardener, M., Garzotti, L., Gaspar, J., Gatto, R., Gaudio, P., Gear, D., Gebhart, T., Gee, S., Gelfusa, M., George, R., Gerasimov, S., Gervasini, G., Gethins, M., Ghani, Z., Gherendi, M., Ghezzi, F., Giacalone, J., Giacomelli, L., Giacometti, G., Gibson, C., Gibson, K., Gil, L., Gillgren, A., Gin, D., Giovannozzi, E., Giroud, C., Glen, R., Gloggler, S., Goff, J., Gohil, P., Goloborodko, V., Gomes, R., Goncalves, B., Goniche, M., Goodyear, A., Gore, S., Gorini, G., Görler, T., Gotts, N., Goulding, R., Gow, E., Graham, B., Graves, J., Greuner, H., Grierson, B., Griffiths, J., Griph, S., Grist, D., Gromelski, W., Groth, M., Grove, R., Gruca, M., Guard, D., Gupta, N., Gurl, C., Gusarov, A., Hackett, L., Hacquin, S., Hager, R., Hagg, L., Hakola, A., Halitovs, M., Hall, S., Hallworth-Cook, S., Ham, C., Hamaguchi, D., Hamed, M., Hamlyn-Harris, C., Hammond, K., Harford, E., Harrison, J., Harting, D., Hatano, Y., Hatch, D., Haupt, T., Hawes, J., Hawkes, N., Hawkins, 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moléculaires (PIIM), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), Institut de Recherche sur la Fusion par confinement Magnétique (IRFM), Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Swiss Plasma Center (SPC), Ecole Polytechnique Fédérale de Lausanne (EPFL), Laboratory for Plasma Physics (LPP), Ecole Royale Militaire / Koninklijke Militaire School (ERM KMS), Kharkiv Institute of Physics and Technology (Ukraine), V.N. Karazin Kharkiv National University (KhNU), Dipartimento di Fisica (Milano), Università degli Studi di Milano = University of Milan (UNIMI), Consiglio Nazionale delle Ricerche [Milano] (CNR), Jozef Stefan Institute [Ljubljana] (IJS), Culham Centre for Fusion Energy (CCFE), Department of Physics and Astronomy [Uppsala], Uppsala University, This work has been carried out within the framework of the EUROfusion Consortium and has received funding from the Euratom research and training programme 2014–2018 and 2019–2020 under Grant agreement No 633053., Mazzi, S, Garcia, J, Zarzoso, D, Kazakov, Y, Ongena, J, Dreval, M, Nocente, M, Stancar, Z, Szepesi, G, Eriksson, J, Sahlberg, A, Benkadda, S, Abid, N, Abraham, K, Abreu, P, Adabonyan, O, Adrich, P, Afzal, M, Ahlgren, T, Aho-Mantila, L, Aiba, N, Airila, M, Akhtar, M, Albanese, R, Alderson-Martin, M, Alegre, D, Aleiferis, S, Aleksa, A, Alessi, E, Aleynikov, P, Algualcil, J, Ali, M, Allinson, M, Alper, B, Alves, E, Ambrosino, G, Ambrosino, R, 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K., Zoulias, I., Zwingmann, W., Zychor, I., JET Contributors, Science and Technology of Nuclear Fusion, EIRES Eng. for Sustainable Energy Systems, Magneto-Hydro-Dynamic Stability of Fusion Plasmas, Applied Physics and Science Education, Kazakov, Yo, VTT Technical Research Centre of Finland, Culham Science Centre, Princeton Plasma Physics Laboratory, Department of Applied Physics, European Commission, Forschungszentrum Jülich, Universidade Lisboa, Fusion and Plasma Physics, University of Milan - Bicocca, Aalto University, General Atomics, ITER, University of Toyama, CEA, Oak Ridge National Laboratory, Technical University of Madrid, Swiss Federal Institute of Technology Lausanne, Dutch Institute for Fundamental Energy Research, Royal Military Academy, Seoul National University, Chalmers University of Technology, Max Planck Institute for Plasma Physics, KTH Royal Institute of Technology, and Aalto-yliopisto

Subjects
[PHYS]Physics [physics], Settore FIS/01, Settore ING-IND/18 - Fisica dei Reattori Nucleari, General Physics and Astronomy, simulation, magnetically confined plasma, nuclear fusion, tokamaks, turbulence suppression, Plasma, [PHYS.PHYS.PHYS-PLASM-PH]Physics [physics]/Physics [physics]/Plasma Physics [physics.plasm-ph], confinement, transport, Alpha particles, Fusion reactors, Turbulence, physics
Abstract

openaire: EC/H2020/633053/EU//EUROfusion Funding Information: We thank M. Baruzzo and F. Nave for the preparation and execution of JET experiments discussed in this paper; E. de la Luna for support in detailing the experimental diagnostics of JET; A. Ho for assistance in processing the experimental data; T. Görler for providing essential advice to ensure the correct numerical setup for the GENE modelling reported in this paper; Y. Camenen, X. Garbet and A. Bierwage for fruitful discussions about the gyrokinetic analyses; G. Giruzzi for valuable suggestions on the article strategy. The simulations were performed on the IRENE Joliot-Curie HPC system, in the framework of the PRACE projects IONFAST and AFIETC, led by J. Garcia, and on the CINECA Marconi HPC within the project GENE4EP, led by D. Zarzoso. This work has been carried out within the framework of the EUROfusion Consortium and has received funding from the Euratom research and training programme 2014-2018 and 2019-2020 under grant agreement no. 633053. The views and opinions express herein do not necessarily reflect those of the European Commission. Part of the work by Ye. O. Kazakov and J.Ongena was also carried out in the framework of projects done for the ITER Scientist Fellow Network (ISFN). Funding Information: We thank M. Baruzzo and F. Nave for the preparation and execution of JET experiments discussed in this paper; E. de la Luna for support in detailing the experimental diagnostics of JET; A. Ho for assistance in processing the experimental data; T. Görler for providing essential advice to ensure the correct numerical setup for the GENE modelling reported in this paper; Y. Camenen, X. Garbet and A. Bierwage for fruitful discussions about the gyrokinetic analyses; G. Giruzzi for valuable suggestions on the article strategy. The simulations were performed on the IRENE Joliot-Curie HPC system, in the framework of the PRACE projects IONFAST and AFIETC, led by J. Garcia, and on the CINECA Marconi HPC within the project GENE4EP, led by D. Zarzoso. This work has been carried out within the framework of the EUROfusion Consortium and has received funding from the Euratom research and training programme 2014-2018 and 2019-2020 under grant agreement no. 633053. The views and opinions express herein do not necessarily reflect those of the European Commission. Part of the work by Ye. O. Kazakov and J.Ongena was also carried out in the framework of projects done for the ITER Scientist Fellow Network (ISFN). Publisher Copyright: © 2022, The Author(s), under exclusive licence to Springer Nature Limited. Alpha particles with energies on the order of megaelectronvolts will be the main source of plasma heating in future magnetic confinement fusion reactors. Instead of heating fuel ions, most of the energy of alpha particles is transferred to electrons in the plasma. Furthermore, alpha particles can also excite Alfvénic instabilities, which were previously considered to be detrimental to the performance of the fusion device. Here we report improved thermal ion confinement in the presence of megaelectronvolts ions and strong fast ion-driven Alfvénic instabilities in recent experiments on the Joint European Torus. Detailed transport analysis of these experiments reveals turbulence suppression through a complex multi-scale mechanism that generates large-scale zonal flows. This holds promise for more economical operation of fusion reactors with dominant alpha particle heating and ultimately cheaper fusion electricity.

Published
2022

43. Enhanced performance in fusion plasmas through turbulence suppression by megaelectronvolt ions

Author

Mazzi, S, Garcia, J, Zarzoso, D, Kazakov, Y, Ongena, J, Dreval, M, Nocente, M, Stancar, Z, Szepesi, G, Eriksson, J, Sahlberg, A, Benkadda, S, Abid, N, Abraham, K, Abreu, P, Adabonyan, O, Adrich, P, Afzal, M, Ahlgren, T, Aho-Mantila, L, Aiba, N, Airila, M, Akhtar, M, Albanese, R, Alderson-Martin, M, Alegre, D, Aleiferis, S, Aleksa, A, Alessi, E, Aleynikov, P, Algualcil, J, Ali, M, Allinson, M, Alper, B, Alves, E, Ambrosino, G, Ambrosino, R, Andersson Sunden, E, Andrew, P, Angelini, B, Angioni, C, Antoniou, I, Appel, L, Appelbee, C, Aria, S, Ariola, M, Artaserse, G, Arter, W, Artigues, V, Asakura, N, Ash, A, Ashikawa, N, Aslanyan, V, Astrain, M, Asztalos, O, Auld, D, Auriemma, F, Austin, Y, Avotina, L, Aymerich, E, Baciero, A, Bairaktaris, F, Balbin, J, Balbinot, L, Balboa, I, Balden, M, Balshaw, C, Balshaw, N, Bandaru, V, Banks, J, Baranov, Y, Barcellona, C, Barnard, A, Barnard, M, Barnsley, R, Barth, A, Baruzzo, M, Barwell, S, Bassan, M, Batista, A, Batistoni, P, Baumane, L, Bauvir, B, Baylor, L, Beaumont, P, Beckett, D, Begolli, A, Beidler, M, Bekris, N, Beldishevski, M, Belli, E, Belli, F, Belonohy, E, Ben Yaala, M, Benayas, J, Bentley, J, Bergsaker, H, Bernardo, J, Bernert, M, Berry, M, Bertalot, L, Betar, H, Beurskens, M, Bickerton, S, Bieg, B, Bielecki, J, Bierwage, A, Biewer, T, Bilato, R, Bilkova, P, Birkenmeier, G, Bishop, H, Bizarro, J, Blackburn, J, Blanchard, P, Blatchford, P, Bobkov, V, Boboc, A, Bohm, P, Bohm, T, Bolshakova, I, Bolzonella, T, Bonanomi, N, Bonfiglio, D, Bonnin, X, Bonofiglo, P, Boocock, S, Booth, A, Booth, J, Borba, D, Borodin, D, Borodkina, I, Boulbe, C, Bourdelle, C, Bowden, M, Boyd, K, Bozicevic Mihalic, I, Bradnam, S, Braic, V, Brandt, L, Bravanec, R, Breizman, B, Brett, A, Brezinsek, S, Brix, M, Bromley, K, Brown, B, Brunetti, D, Buckingham, R, Buckley, M, Budny, R, Buermans, J, Bufferand, H, Buratti, P, Burgess, A, Buscarino, A, Busse, A, Butcher, D, de la Cal, E, Calabro, G, Calacci, L, Calado, R, Camenen, Y, Canal, G, Cannas, B, 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R., Kotschenreuther M., Koubiti M., Kowalska-Strzeciwilk E., Koziol K., Krasilnikov V., Kresina M., Krieger K., Krishnan N., Krivska A., Kruezi U., Ksiazek I., Kukushkin A. B., Kumpulainen H., Kurki-Suonio T., Kurotaki H., Kwak S., Kwon O. J., Laguardia L., Lagzdina E., Lahtinen A., Laing A., Lam N., Lambertz H. T., Lane B., Lane C., Lascas Neto E., Laszynska E., Lawson K. D., Lazaros A., Lazzaro E., Learoyd G., Lee C., Lee S. E., Leerink S., Leeson T., Lefebvre X., Leggate H. J., Lehmann J., Lehnen M., Leichtle D., Leipold F., Lengar I., Lennholm M., Leon Gutierrez E., Lepiavko B., Leppanen J., Lerche E., Lescinskis A., Lewis J., Leysen W., Li L., Li Y., Likonen J., Linsmeier C., Lipschultz B., Litaudon X., Litherland-Smith E., Liu F., Loarer T., Loarte A., Lobel R., Lomanowski B., Lomas P. J., Lopez J. M., Lorenzini R., Loreti S., Losada U., Loschiavo V. P., Loughlin M., Louka Z., Lovell J., Lowe T., Lowry C., Lubbad S., Luce T., Lucock R., Luna C., de la Luna E., Lungaroni M., Lungu C. P., Lunt T., Lutsenko V., Lyons B., Lyssoivan A., Machielsen M., Macusova E., Maenpaa R., Maggi C. F., Maggiora R., Magness M., Mahesan S., Maier H., Mailloux J., Maingi R., Malinowski K., Manas P., Mantica P., Mantsinen M. J., Manyer J., Manzanares A., Maquet P., Marceca G., Marchetto C., Marchuk O., Mariani A., Mariano G., Marin M., Marinelli M., Markovic T., Marocco D., Marot L., Marsden S., Marsh J., Marshall R., Martellucci L., Martin A., Martin A. J., Martone R., Maruyama S., Maslov M., Masuzaki S., Matejcik S., Mattei M., Matthews G. F., Matveev D., Matveeva E., Mauriya A., Maviglia F., Mayer M., Mayoral M. -L., Mazzotta C., McAdams R., McCarthy P. J., McClements K. G., McClenaghan J., McCullen P., McDonald D. C., McGuckin D., McHugh D., McIntyre G., McKean R., McKehon J., McMillan B., McNamee L., McShee A., Meakins A., Medley S., Meekes C. J., Meghani K., Meigs A. G., Meisl G., Meitner S., Menmuir S., Mergia K., Merriman S., Mertens P., Messiaen A., Michling R., Middleton P., Middleton-Gear D., Mietelski J., Milanesio D., Milani E., Militello F., Militello Asp A., Milnes J., Milocco A., Miloshevsky G., Minghao C., Minucci S., Miron I., Miyamoto M., Mlynar J., Moiseenko V., Monaghan P., Monakhov I., Moody T., Moon S., Mooney R., Moradi S., Morales J., Morales R. B., Mordijck S., Moreira L., Morgan L., Moro F., Morris J., Morrison K. -M., Moser L., Moulton D., Mrowetz T., Mundy T., Muraglia M., Murari A., Muraro A., Muthusonai N., N'Konga B., Na Y. -S., Nabais F., Naden M., Naish J., Naish R., Napoli F., Nardon E., Naulin V., Nave M. F. F., Nedzelskiy I., Nestoras I., Neu R., Ng S., Nicassio M., Nielsen A. H., Nina D., Nishijima D., Noble C., Nobs C. R., Nodwell D., Nordlund K., Nordman H., Normanton R., Noterdaeme J. -M., Nowak S., Nunn E., Nystrom H., Oberparleiter M., Obryk B., O'Callaghan J., Odupitan T., Oliver H. J. 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C., Olney R., O'Mullane M., Organ E., Orsitto F., Orszagh J., Osborne T., Otin R., Otsuka T., Owen A., Oya Y., Oyaizu M., Paccagnella R., Pace N., Packer L. W., Paige S., Pajuste E., Palade D., Pamela S. J. P., Panadero N., Panontin E., Papadopoulos A., Papp G., Papp P., Parail V. V., Pardanaud C., Parisi J., Parra Diaz F., Parsloe A., Parsons M., Parsons N., Passeri M., Patel A., Pau A., Pautasso G., Pavlichenko R., Pavone A., Pawelec E., Soldan C. P., Peacock A., Pearce M., Peluso E., Penot C., Pepperell K., Pereira R., Pereira T., Cippo E. P., Pereslavtsev P., von Thun C. P., Pericoli V., Perry D., Peterka M., Petersson P., Petravich G., Petrella N., Peyman M., Pillon M., Pinches S., Pintsuk G., de Sa W. P., dos Reis A. P., Piron C., Piron L., Pironti A., Pitts R., van de Plassche K. L., Platt N., Plyusnin V., Podesta M., Pokol G., Poli F. M., Pompilian O. G., Popovichev S., Poradzinski M., Porfiri M. T., Porkolab M., Porosnicu C., Porton M., Poulipoulis G., Predebon I., Prestopino G., Price C., Price D., Price M., Primetzhofer D., Prior P., Provatas G., Pucella G., Puglia P., Purahoo K., Pusztai I., Putignano O., Putterich T., Quercia A., Rachlew E., Radulescu G., Radulovic V., Rainford M., Raj P., Ralph G., Ramogida G., Rasmussen D., Rasmussen J. J., Ratta G., Ratynskaia S., Rebai M., Refy D., Reichle R., Reinke M., Reiser D., Reux C., Reynolds S., Richiusa M. L., Richyal S., Rigamonti D., Rimini F. G., Risner J., Riva M., Rivero-Rodriguez J., Roach C. M., Robins R., Robinson S., Robson D., Rodrigues P., Rodriguez Ramos M., Rodriguez-Fernandez P., Romanelli F., Romanelli M., Romanelli S., Romazanov J., Rossi R., Rowe S., Rowlands D., Rubel M., Rubinacci G., Rubino G., Ruchko L., Ruiz M., Ruiz J. R., Ruset C., Rzadkiewicz J., Saarelma S., Safi E., Salewski M., Salmi A., Salmon R., Salzedas F., Sanders I., Sandiford D., Santos B., Santucci A., Sarkimaki K., Sarwar R., Sarychev I., Sauter O., Sauwan P., Scapin N., Schluck F., Schmid K., Schmuck S., Schneider M., Schneider P. A., Schworer D., Scott G., Scott M., Scraggs D., Scully S., Segato M., Seo J., Sergienko G., Sertoli M., Sharapov S. E., Shaw A., Sheikh H., Sheikh U., Shepherd A., Shigin P., Shinohara K., Shiraiwa S., Shiraki D., Short M., Sias G., Silburn S. A., Silva A., Silva C., Silva J., Silvagni D., Simfukwe D., Simpson J., Sinclair D., Sipila S. K., Sips A. C. C., Siren P., Sirinelli A., Sjostrand H., Skinner N., Slater J., Smith N., Smith P., Snell J., Snoep G., Snoj L., Snyder P., Soare S., Solano E. R., Solokha V., Somers A., Sommariva C., Soni K., Sorokovoy E., Sos M., Sousa J., Sozzi C., Spagnolo S., Spelzini T., Spineanu F., Spong D., Sprada D., Sridhar S., Srinivasan C., Stables G., Staebler G., Stamatelatos I., Staniec P., Stankunas G., Stead M., Stefanikova E., Stephen A., Stephens J., Stevenson P., Stojanov M., Strand P., Strauss H. R., Strikwerda S., Strom P., Stuart C. I., Studholme W., Subramani M., Suchkov E., Sumida S., Sun H. J., Susts T. E., Svensson J., Svoboda J., Sweeney R., Sytnykov D., Szabolics T., Tabia B., Tadic T., Tal B., Tala T., Tallargio A., Tamain P., Tan H., Tanaka K., Tang W., Tardocchi M., Taylor D., Teimane A. S., Telesca G., Teplukhina A., Terentyev D., Terra A., Terranova D., Terranova N., Testa D., Tholerus E., Thomas J., Thoren E., Thorman A., Tierens W., Tinguely R. A., Tipton A., Todd H., Tokitani M., Tolias P., Tomes M., Tookey A., Torikai Y., von Toussaint U., Tsavalas P., Tskhakaya D., Turner I., Turner M., Turner M. M., Turnyanskiy M., Tvalashvili G., Tyrrell S., Tyshchenko M., Uccello A., Udintsev V., Urbanczyk G., Vadgama A., Valcarcel D., Valisa M., Vallejos Olivares P., Vallhagen O., Valovic M., Van Eester D., Varje J., Vartanian S., Vasilopoulou T., Vayakis G., Vecsei M., Vega J., Ventre S., Verdoolaege G., Verona C., Rinati G. V., Veshchev E., Vianello N., Viezzer E., Vignitchouk L., Vila R., Villari R., Villone F., Vincenzi P., Viola B., Virtanen A. J., Vitins A., Vizvary Z., Vlad G., Vlad M., Vondracek P., de Vries P., Wakeling B., Walkden N. R., Walker M., Walker R., Walsh M., Wang E., Wang N., Warder S., Warren R., Waterhouse J., Watts C., Wauters T., Weckmann A., Wedderburn Maxwell H., Weiland M., Weisen H., Weiszflog M., Welch P., Wendler N., West A., Wheatley M., Wheeler S., Whitehead A., Whittaker D., Widdowson A., Wiesen S., Wilkinson J., Williams J. C., Willoughby D., Wilson I., Wilson J., Wilson T., Wischmeier M., Wise P., Withenshaw G., Withycombe A., Witts D., Wojcik-Gargula A., Wolfrum E., Wood R., Woodley C., Woodley R., Woods B., Wright J., Wright J. C., Xu T., Yadikin D., Yajima M., Yakovenko Y., Yang Y., Yanling W., Yanovskiy V., Young I., Young R., Zabolockis R. J., Zacks J., Zagorski R., Zaitsev F. S., Zakharov L., Zarins A., Zastrow K. -D., Zayachuk Y., Zerbini M., Zhang W., Zhou Y., Zlobinski M., Zocco A., Zohar A., Zoita V., Zoletnik S., Zotta V. K., Zoulias I., Zwingmann W., and Zychor I.

Abstract

Alpha particles with energies on the order of megaelectronvolts will be the main source of plasma heating in future magnetic confinement fusion reactors. Instead of heating fuel ions, most of the energy of alpha particles is transferred to electrons in the plasma. Furthermore, alpha particles can also excite Alfvénic instabilities, which were previously considered to be detrimental to the performance of the fusion device. Here we report improved thermal ion confinement in the presence of megaelectronvolts ions and strong fast ion-driven Alfvénic instabilities in recent experiments on the Joint European Torus. Detailed transport analysis of these experiments reveals turbulence suppression through a complex multi-scale mechanism that generates large-scale zonal flows. This holds promise for more economical operation of fusion reactors with dominant alpha particle heating and ultimately cheaper fusion electricity.

Published
2022

48. Spectral entropy provides separation between Alzheimer’s disease patients and controls:a study of fNIRS

Author

Ferdinando, H. (H.), Moradi, S. (S.), Korhonen, V. (V.), Helakari, H. (H.), Kiviniemi, V. (V.), Myllylä, T. (T.), Ferdinando, H. (H.), Moradi, S. (S.), Korhonen, V. (V.), Helakari, H. (H.), Kiviniemi, V. (V.), and Myllylä, T. (T.)

Abstract

Functional near-infrared spectroscopy (fNIRS) is commonly used as a non-invasive tool to measure cerebral neurovascular dynamics. Its potential for diagnostics of various brain disorders has been already demonstrated in many recent studies, including Alzheimer’s disease (AD). fNIRS studies are usually based on comparing hemoglobin measurements at baseline and during a specific task. At present, many proposed methods using fNIRS to diagnose AD involve certain tasks, which may be challenging for the elderly and patients with cognitive decline. Here, we propose a method to characterize AD patients and control in resting state, by applying spectral entropy (SE) analysis on oxyhemoglobin and deoxyhemoglobin, HbO and HbR, respectively, and total hemoglobin (HbT) based on fNIRS signals measured from the left and right sides of the forehead. We applied SE to very low frequency (VLF) (0.008–0.1 Hz), respiratory (0.1–0.6 Hz), and cardiac (0.6–5 Hz) bands to find out which band delivered the optimum result. Next, a t test with 0.05 significant level was performed to compare SE values of AD patients and controls. Results from the VLF band looked promising as SE values from AD patients were always significantly higher than those from controls. In addition, this phenomenon was consistent for both sides of the forehead. However, significant differences in SE values in the respiratory band were found from the left hemisphere only, and in the cardiac band from the right hemisphere only. SE value from the VLF band supports a strong argument that it provides good predictability related to the development of AD. We demonstrated that SE of brain fNIRS signal can be an useful biomarker for Alzheimer’s disease pathology.

Published
2023

49. Fractional amplitude of physiological fluctuations of resting state fNIRS in Alzheimer’s disease patient and healthy control

Author

Ferdinando, H. (Hany), Moradi, S. (Sadegh), Korhonen, V. (Vesa), Kiviniemi, V. (Vesa), Myllylä, T. (Teemu), Ferdinando, H. (Hany), Moradi, S. (Sadegh), Korhonen, V. (Vesa), Kiviniemi, V. (Vesa), and Myllylä, T. (Teemu)

Abstract

Functional magnetic resonance imaging (fMRI) is a common medical device to diagnose Alzheimer’s disease (AD), but it is not for all subjects due to its cost and other issues. We investigated the potential of functional near-infrared spectroscopy (fNIRS) to separate AD patients from controls as a pre-screening prior to more thorough examination using fMRI. For this purpose, two-channel fNIRS device with 690 nm and 830 nm, sampled at 10 Hz, was placed on the forehead with 3 cm distance between light source and detector to provide resting state fNIRS signals from both sides of pre-frontal cortex. We applied fractional amplitude of physiological fluctuation (fAPF), modified from fractional amplitude of low frequency fluctuation (fALFF), to oxy-, deoxy-, and total-hemoglobin in very low frequency (0.008‐0.1 Hz), respiratory (0.1‐0.6 Hz), and cardiac (0.6‐5 Hz) bands. A t-test at 0.05 significance level was used to evaluate if the fAPF score from AD patients and healthy controls is significantly different. We found that fAPF score of total hemoglobin from both side at cardiac band showed its potential to distinguish AD patients from healthy controls. This finding was in-line with the recent finding that heart failure may co-occur in AD patients with the prevalence of one third of cases.

Published
2023

50. The JET hybrid scenario in Deuterium, Tritium and Deuterium-Tritium

Author

Hobirk, J., Challis, C. D., Kappatou, A., Lerche, E., Keeling, D., King, D., Aleiferis, S., Alessi, E., Angioni, C., Auriemma, F., Baruzzo, M., Belonohy, E., Bernardo, J., Boboc, A., Carvalho, I. S., Carvalho, P., Casson, F. J., Chomiczewska, A., Citrin, J., Coffey, I. H., Conway, N. J., Douai, D., Delabie, E., Eriksson, Benjamin, Eriksson, Jacob, Ficker, O., Field, A. R., Fontana, M., Fontdecaba, J. M., Frassinetti, L., Frigione, D., Gallart, D., Garcia, J., Gelfusa, M., Ghani, Z., Giacomelli, L., Giovannozzi, E., Giroud, C., Goniche, M., Gromelski, W., Hacquin, S., Ham, C., Hawkes, N. C., Henriques, R. B., Hillesheim, J. C., Ho, A., Horvath, L., Ivanova-Stanik, I., Jacquet, P., Jaulmes, F., Joffrin, E., Kim, H. T., Kiptily, V., Kirov, K., Kos, D., Kowalska-Strzeciwilk, E., Kumpulainen, H., Lawson, K., Lennholm, M., Litaudon, X., Litherland-Smith, E., Lomas, P. J., de la Luna, E., Maggi, C. F., Mailloux, J., Mantsinen, M. J., Maslov, M., Matthews, G., Mcclements, K. G., Meigs, A. G., Menmuir, S., Milocco, A., Miron, I. G., Moradi, S., Morales, R. B., Nowak, S., Orsitto, F., Patel, A., Piron, L., Prince, C., Pucella, G., Peluso, E., von Thun, C. Perez, Rachlew, E., Reux, C., Rimini, F., Saarelma, S., Schneider, P. A., Scully, S., Sertoli, M., Sharapov, S., Shaw, A., Silburn, S., Sips, A., Siren, P., Sozzi, C., Solano, E. R., Stancar, Z., Stankunas, G., Stuart, C., Sun, H. J., Szepesi, G., Valcarcel, D., Valisa, M., Verdoolaege, G., Viola, B., Wendler, N., Zerbini, M., Hobirk, J., Challis, C. D., Kappatou, A., Lerche, E., Keeling, D., King, D., Aleiferis, S., Alessi, E., Angioni, C., Auriemma, F., Baruzzo, M., Belonohy, E., Bernardo, J., Boboc, A., Carvalho, I. S., Carvalho, P., Casson, F. J., Chomiczewska, A., Citrin, J., Coffey, I. H., Conway, N. J., Douai, D., Delabie, E., Eriksson, Benjamin, Eriksson, Jacob, Ficker, O., Field, A. R., Fontana, M., Fontdecaba, J. M., Frassinetti, L., Frigione, D., Gallart, D., Garcia, J., Gelfusa, M., Ghani, Z., Giacomelli, L., Giovannozzi, E., Giroud, C., Goniche, M., Gromelski, W., Hacquin, S., Ham, C., Hawkes, N. C., Henriques, R. B., Hillesheim, J. C., Ho, A., Horvath, L., Ivanova-Stanik, I., Jacquet, P., Jaulmes, F., Joffrin, E., Kim, H. T., Kiptily, V., Kirov, K., Kos, D., Kowalska-Strzeciwilk, E., Kumpulainen, H., Lawson, K., Lennholm, M., Litaudon, X., Litherland-Smith, E., Lomas, P. J., de la Luna, E., Maggi, C. F., Mailloux, J., Mantsinen, M. J., Maslov, M., Matthews, G., Mcclements, K. G., Meigs, A. G., Menmuir, S., Milocco, A., Miron, I. G., Moradi, S., Morales, R. B., Nowak, S., Orsitto, F., Patel, A., Piron, L., Prince, C., Pucella, G., Peluso, E., von Thun, C. Perez, Rachlew, E., Reux, C., Rimini, F., Saarelma, S., Schneider, P. A., Scully, S., Sertoli, M., Sharapov, S., Shaw, A., Silburn, S., Sips, A., Siren, P., Sozzi, C., Solano, E. R., Stancar, Z., Stankunas, G., Stuart, C., Sun, H. J., Szepesi, G., Valcarcel, D., Valisa, M., Verdoolaege, G., Viola, B., Wendler, N., and Zerbini, M.

Abstract

The JET hybrid scenario has been developed from low plasma current carbon wall discharges to the record-breaking Deuterium-Tritium plasmas obtained in 2021 with the ITER-like Be/W wall. The development started in pure Deuterium with refinement of the plasma current, and toroidal magnetic field choices and succeeded in solving the heat load challenges arising from 37 MW of injected power in the ITER like wall environment, keeping the radiation in the edge and core controlled, avoiding MHD instabilities and reaching high neutron rates. The Deuterium hybrid plasmas have been re-run in Tritium and methods have been found to keep the radiation controlled but not at high fusion performance probably due to time constraints. For the first time this scenario has been run in Deuterium-Tritium (50:50). These plasmas were re-optimised to have a radiation-stable H-mode entry phase, good impurity control through edge Ti gradient screening and optimised performance with fusion power exceeding 10 MW for longer than three alpha particle slow down times, 8.3 MW averaged over 5 s and fusion energy of 45.8 MJ.

Published
2023
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