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13 results on '"Moran Torres, Juan"'

6. The pleiotropic phenotype of FlbA of Aspergillus niger is explained in part by the activity of seven of its downstream-regulated transcription factors

Author

Sub Molecular Microbiology, Afd Biomol.Mass Spect. and Proteomics, Molecular Microbiology, Chen, Xiaoyi, Moran Torres, Juan P., Jan Vonk, Peter, Damen, J. Mirjam A., Reiding, Karli R., Dijksterhuis, Jan, Lugones, Luis G., Wösten, Han A.B., Sub Molecular Microbiology, Afd Biomol.Mass Spect. and Proteomics, Molecular Microbiology, Chen, Xiaoyi, Moran Torres, Juan P., Jan Vonk, Peter, Damen, J. Mirjam A., Reiding, Karli R., Dijksterhuis, Jan, Lugones, Luis G., and Wösten, Han A.B.

Published
2024

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Author

Molecular Microbiology, Biomolecular Mass Spectrometry and Proteomics, Sub Molecular Microbiology, Afd Biomol.Mass Spect. and Proteomics, Lyu, Jun, Torchia, Costanza, Post, Harm, Moran Torres, Juan P, Altelaar, A F Maarten, de Cock, Hans, Wösten, Han A B, Molecular Microbiology, Biomolecular Mass Spectrometry and Proteomics, Sub Molecular Microbiology, Afd Biomol.Mass Spect. and Proteomics, Lyu, Jun, Torchia, Costanza, Post, Harm, Moran Torres, Juan P, Altelaar, A F Maarten, de Cock, Hans, and Wösten, Han A B

Published
2023

10. Heterogeneity in Spore Aggregation and Germination Results in Different Sized, Cooperative Microcolonies in an Aspergillus niger Culture

Author

Lyu, Jun, Tegelaar, Martin, Post, Harm, Moran Torres, Juan, Torchia, Costanza, Altelaar, A F Maarten, Bleichrodt, Robert-Jan, de Cock, Hans, Lugones, Luis G, Wösten, Han A B, Lyu, Jun, Tegelaar, Martin, Post, Harm, Moran Torres, Juan, Torchia, Costanza, Altelaar, A F Maarten, Bleichrodt, Robert-Jan, de Cock, Hans, Lugones, Luis G, and Wösten, Han A B

Abstract

The fungus Aspergillus niger is among the most abundant fungi in the world and is widely used as a cell factory for protein and metabolite production. This fungus forms asexual spores called conidia that are used for dispersal. Notably, part of the spores and germlings aggregate in an aqueous environment. The aggregated conidia/ germlings give rise to large microcolonies, while the nonaggregated spores/germlings result in small microcolonies. Here, it is shown that small microcolonies release a larger variety and quantity of secreted proteins compared to large microcolonies. Yet, the secretome of large microcolonies has complementary cellulase activity with that of the small microcolonies. Also, large microcolonies are more resistant to heat and oxidative stress compared to small microcolonies, which is partly explained by the presence of nongerminated spores in the core of the large microcolonies. Together, it is proposed that heterogeneity in germination and aggregation has evolved to form a population of different sized A. niger microcolonies, thereby increasing stress survival and producing a meta-secretome more optimally suited to degrade complex substrates.

Published
2023

11. Heterogeneity in Spore Aggregation and Germination Results in Different Sized, Cooperative Microcolonies in an Aspergillus niger Culture

Author

Molecular Microbiology, Biomolecular Mass Spectrometry and Proteomics, Sub Molecular Microbiology, Afd Biomol.Mass Spect. and Proteomics, Sub Biomol.Mass Spect. and Proteomics, Lyu, Jun, Tegelaar, Martin, Post, Harm, Moran Torres, Juan, Torchia, Costanza, Altelaar, A F Maarten, Bleichrodt, Robert-Jan, de Cock, Hans, Lugones, Luis G, Wösten, Han A B, Molecular Microbiology, Biomolecular Mass Spectrometry and Proteomics, Sub Molecular Microbiology, Afd Biomol.Mass Spect. and Proteomics, Sub Biomol.Mass Spect. and Proteomics, Lyu, Jun, Tegelaar, Martin, Post, Harm, Moran Torres, Juan, Torchia, Costanza, Altelaar, A F Maarten, Bleichrodt, Robert-Jan, de Cock, Hans, Lugones, Luis G, and Wösten, Han A B

Published
2023

12. Inheritable CRISPR based epigenetic modification in a fungus

Author

Molecular Microbiology, Sub Molecular Microbiology, Chen, Xiaoyi, Moran Torres, Juan P, Li, Yiling, Lugones, Luis G, Wösten, Han A B, Molecular Microbiology, Sub Molecular Microbiology, Chen, Xiaoyi, Moran Torres, Juan P, Li, Yiling, Lugones, Luis G, and Wösten, Han A B

Published
2023

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