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39 results on '"Morel, Veronique"'

1. Bortezomib and high-dose melphalan conditioning regimen in frontline multiple myeloma: an IFM randomized phase 3 study

Author

Roussel, Murielle, Lauwers-Cances, Valérie, Macro, Margaret, Leleu, Xavier, Royer, Bruno, Hulin, Cyrille, Karlin, Lionel, Perrot, Aurore, Touzeau, Cyrille, Chrétien, Marie-Lorraine, Rigaudeau, Sophie, Dib, Mamoun, Nicolas-Virelizier, Emmanuelle, Escoffre-Barbe, Martine, Belhadj, Karim, Mariette, Clara, Stoppa, Anne-Marie, Araujo, Carla, Doyen, Chantal, Fontan, Jean, Kolb, Brigitte, Garderet, Laurent, Brechignac, Sabine, Malfuson, Jean-Valère, Jaccard, Arnaud, Lenain, Pascal, Borel, Cécile, Hebraud, Benjamin, Benbrahim, Omar, Dorvaux, Véronique, Manier, Salomon, Augeul-Meunier, Karine, Vekemans, Marie-Christiane, Randriamalala, Edouard, Chaoui, Driss, Caers, Jo, Chaleteix, Carine, Benboubker, Lofti, Vincent, Laure, Glaisner, Sylvie, Zunic, Patricia, Slama, Borhane, Eveillard, Jean-Richard, Humbrecht-Kraut, Catherine, Morel, Véronique, Mineur, Philippe, Eisenmann, Jean-Claude, Demarquette, Hélène, Richez, Valentine, Vignon, Marguerite, Caillot, Denis, Facon, Thierry, Moreau, Philippe, Colin, Anne-Laurène, Olivier, Pascale, Wuilleme, Soraya, Avet-Loiseau, Hervé, Corre, Jill, and Attal, Michel

Published
2022
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9. Post-transplantation Burkitt lymphoma: a retrospective study of 55 patients

Author

Walczak, Pierre, primary, Choquet, Sylvain, additional, Dantal, Jacques, additional, Boutboul, David, additional, Suarez, Felipe, additional, Baron, Marine, additional, Morel, Veronique, additional, Cluzeau, Thomas, additional, Touati, Mohamed, additional, Elias, Michelle, additional, Bachy, Emmanuel, additional, Nicolas-Virelizier, Emmanuelle, additional, Houot, Roch, additional, Venton, Geoffroy, additional, Jacquet, Caroline, additional, Moles-Moreau, Marie-Pierre, additional, Jardin, Fabrice, additional, Durot, Eric, additional, Balegroune, Noureddine, additional, Ecotiere, Laure, additional, Guieze, Romain, additional, Kamar, Nassim, additional, Ysebaert, Loic, additional, Couzi, Lionel, additional, Gonzalez, Hugo, additional, Roulin, Louise, additional, Ou, Kevin, additional, Caillard, Sophie, additional, Zimmermann, Heiner, additional, Trappe, Ralf Ulrich, additional, and Roos-Weil, Damien, additional

Published
2023
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10. Post-transplantation Burkitt lymphoma: a retrospective study of 55 patients

Author

Walczak, Pierre, Choquet, Sylvain, Dantal, Jacques, Boutboul, David, Suarez, Felipe, Baron, Marine, Morel, Veronique, Cluzeau, Thomas, Touati, Mohamed, Elias, Michelle, Bachy, Emmanuel, Nicolas-Virelizier, Emmanuelle, Houot, Roch, Venton, Geoffroy, Jacquet, Caroline, Moles-Moreau, Marie-Pierre, Jardin, Fabrice, Durot, Eric, Balegroune, Noureddine, Ecotiere, Laure, Guieze, Romain, Kamar, Nassim, Ysebaert, Loic, Couzi, Lionel, Gonzalez, Hugo, Roulin, Louise, Ou, Kevin, Caillard, Sophie, Zimmermann, Heiner, Trappe, Ralf Ulrich, Roos-Weil, Damien, Walczak, Pierre, Choquet, Sylvain, Dantal, Jacques, Boutboul, David, Suarez, Felipe, Baron, Marine, Morel, Veronique, Cluzeau, Thomas, Touati, Mohamed, Elias, Michelle, Bachy, Emmanuel, Nicolas-Virelizier, Emmanuelle, Houot, Roch, Venton, Geoffroy, Jacquet, Caroline, Moles-Moreau, Marie-Pierre, Jardin, Fabrice, Durot, Eric, Balegroune, Noureddine, Ecotiere, Laure, Guieze, Romain, Kamar, Nassim, Ysebaert, Loic, Couzi, Lionel, Gonzalez, Hugo, Roulin, Louise, Ou, Kevin, Caillard, Sophie, Zimmermann, Heiner, Trappe, Ralf Ulrich, and Roos-Weil, Damien

Published
2023

12. Efficacy of CAR-T Cells in Primary Central Nervous System Lymphomas: The French Experience of the National LOC Network

Author

Sylvain, Choquet, primary, Le Garff-Tavernier, Magali, additional, Souchet, Laetitia, additional, Roos Weil, Damien, additional, Morel, Veronique, additional, Uzunov, Madalina, additional, Metz, Carole, additional, Nguyen Quoc, Stephanie, additional, Jacque, Nathalie, additional, Gauthier, Nicolas, additional, Willems, Lise, additional, Waultier, Agathe, additional, Salanoubat, Celia, additional, Houot, Roch, additional, Ursu, Renata, additional, Barrie, Maryline, additional, Ahle, Guido, additional, Soussain, Carole, additional, Alcantara, Marion, additional, and Houillier, Caroline, additional

Published
2022
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14. Inflammation in Waldenström macroglobulinemia is associated with 6q deletion and need for treatment initiation

Author

Forgeard, Nathalie, primary, Baron, Marine, additional, Caron, Jonathan, additional, Boccon-Gibod, Clementine, additional, Krzisch, Daphne, additional, Guedes, Nayara, additional, Morel, Veronique, additional, Jacque, Nathalie, additional, Ouzegdouh, Maya, additional, Choquet, Sylvain, additional, Bravetti, Clotilde, additional, Nguyen-Khac, Florence, additional, Chapiro, Elise, additional, Leblond, Veronique, additional, and Roos-Weil, Damien, additional

Published
2022
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17. CAR T-cell therapy in primary central nervous system lymphoma: the clinical experience of the French LOC network

Author

Alcantara, Marion, Houillier, Caroline, Blonski, Marie, Rubio, Marie-Thérèse, Willems, Lise, Rascalou, Agathe Waultier, Le Garff-Tavernier, Magali, Maloum, Karim, Bravetti, Clotilde, Souchet, Laetitia, Roos-Weil, Damien, Morel, Véronique, Uzunov, Madalina, Metz, Carole, Dhib-Charfi, Meriem, Nguyen, Stéphanie, Shor, Natalia, Psimaras, Dimitri, Weiss, Nicolas, Jacque, Nathalie, Solorzano, Silvia, Gauthier, Nicolas, Le Cann, Marie, Norol, Françoise, Soussain, Carole, and Choquet, Sylvain

Published
2022
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20. The Eatl-001 Trial: Results of a Phase 2 Study of Brentuximab Vedotin and CHP Followed By Consolidation with High-Dose Therapy - Autologous Stem-Cell Transplantation (HDT-ASCT) in the Frontline Treatment of Patients with Enteropathy-Associated T-Cell Lymphoma

Author

Sibon, David, primary, Khater, Sherine, additional, Bruneau, Julie, additional, Brouzes, Chantal, additional, Lhermitte, Ludovic, additional, Molina, Thierry Jo, additional, Cartron, Guillaume, additional, Morel, Veronique, additional, Malamut, Georgia, additional, Chauchet, Adrien, additional, Morschhauser, Franck, additional, Perard, Baptiste, additional, Boulet, Jean-Michel, additional, Gauchy, Anne-Cécile, additional, Cerf-Bensussan, Nadine, additional, Macintyre, Elizabeth A., additional, Asnafi, Vahid, additional, Cellier, Christophe, additional, and Hermine, Olivier, additional

Published
2021
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22. The Role of PET-MRI in Multiple Myeloma Patients

Author

Garderet, Laurent, primary, Kharroubi-Lakouas, Driss, additional, roos Weil, Damien, additional, Jacque, Nathalie, additional, Ouzegdouh Ouarab, Maya, additional, Martino, Suella, additional, Morel, Veronique, additional, Grenier, Adrien, additional, Sylvain, Choquet, additional, Leblond, Veronique, additional, Kas, Aurelie, additional, and Lucidarme, Olivier, additional

Published
2020
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24. Transoral vertebroplasty for the C1 lateral mass

Author

Clarençon, Frédéric, primary, Shotar, Eimad, additional, Cormier, Evelyne, additional, Premat, Kevin, additional, Drir, Mehdi, additional, Lahlou, Ghizlene, additional, Morel, Veronique, additional, Spano, Jean-Philippe, additional, Bonaccorsi, Raphaël, additional, Di Maria, Federico, additional, Hervochon, Rémi, additional, Pascal-Mousselard, Hugues, additional, and Chiras, Jacques, additional

Published
2020
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25. Repression by Suppressor of Hairless and activation by Notch are required to define a single row of single-minded expressing cells in the Drosophila embryo

Author

Morel, Veronique and Schweisguth, Francois

Subjects
Genetic research -- Analysis, Drosophila -- Research, Cells -- Analysis, Genetic transcription -- Research, Cellular signal transduction -- Analysis, Biological sciences
Abstract

Research has been conducted on the Notch signal transduction. The binding of DNA and activation of Notch target gene transcription has been discussed.

Published
2000

26. CD19 CAR T-Cell Therapy in Patients with Relapse/Refractory DLBCL: Retrospective Analysis of the Eligibility Criteria

Author

Paillassa, Jérôme, primary, Di Blasi, Roberta, additional, Chevret, Sylvie, additional, Bernard, Sophie, additional, Darmon, Michael, additional, Meignin, Veronique, additional, Deau-Fischer, Bénédicte, additional, Camus, Vincent, additional, Casasnovas, Rene-Olivier, additional, Cartron, Guillaume, additional, Chaoui, Driss, additional, Delwail, Vincent, additional, Feugier, Pierre, additional, Fornecker, Luc Mathieu, additional, Gyan, Emmanuel, additional, Haioun, Corinne, additional, Kuhnowski, Frederique, additional, Malfuson, Jean Valère, additional, Marolleau, Jean-Pierre, additional, Morel, Veronique, additional, Damaj, Gandhi, additional, Quinquenel, Anne, additional, Rigaudeau, Sophie, additional, Salanoubat, Celia, additional, Salmeron, Géraldine, additional, Sibon, David, additional, Azoulay, Elie, additional, Berquier, Maxime, additional, and Thieblemont, Catherine, additional

Published
2019
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27. Gain of the short arm of chromosome 2 (2p gain) has a significant role in drug‐resistant chronic lymphocytic leukemia

Author

Kostopoulou, Fotini, Gabillaud, Clementine, Chapiro, Elise, Grange, Beatrice, Tran, Julie, Bouzy, Simon, Degaud, Michael, Ghamlouch, Hussein, Le Garff‐Tavernier, Magali, Maloum, Karim, Choquet, Sylvain, Leblond, Veronique, Gabarre, Jean, Lavaud, Anne, Morel, Veronique, Roos‐Weil, Damien, Uzunov, Madalina, Guieze, Romain, Bernard, Olivier A., Susin, Santos A., Tournilhac, Olivier, Nguyen‐Khac, Florence, CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Sorbonne Université (SU), Centre de Recherche des Cordeliers (CRC (UMR_S_1138 / U1138)), École Pratique des Hautes Études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), Hématopoïèse normale et pathologique (U1170 Inserm), Université Paris-Sud - Paris 11 (UP11)-Institut Gustave Roussy (IGR)-Institut National de la Santé et de la Recherche Médicale (INSERM), Université Paris-Saclay, Role of intra-Clonal Heterogeneity and Leukemic environment in ThErapy Resistance of chronic leukemias (CHELTER), Université Clermont Auvergne [2017-2020] (UCA [2017-2020]), Institut Gustave Roussy (IGR), Service d'Hématologie Biologique [CHU Pitié-Salpêtrière], Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), École pratique des hautes études (EPHE), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Sud - Paris 11 (UP11)-Institut Gustave Roussy (IGR), Service d'Hématologie clinique [CHU Pitié-Salpêtrière], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), and Gestionnaire, Hal Sorbonne Université

Subjects
[SDV.MHEP.HEM] Life Sciences [q-bio]/Human health and pathology/Hematology, Adult, Male, Immunoglobulin Variable Region, Antineoplastic Agents, [SDV.CAN]Life Sciences [q-bio]/Cancer, Polymorphism, Single Nucleotide, Immunophenotyping, Time-to-Treatment, [SDV.CAN] Life Sciences [q-bio]/Cancer, Recurrence, immune system diseases, hemic and lymphatic diseases, [SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN], Antineoplastic Combined Chemotherapy Protocols, Chromosome Duplication, Humans, Longitudinal Studies, Protein Kinase Inhibitors, In Situ Hybridization, Fluorescence, Original Research, Cancer Biology, Aged, Chromosome Aberrations, drug resistance, 2p gain, [SDV.MHEP.HEM]Life Sciences [q-bio]/Human health and pathology/Hematology, Middle Aged, Prognosis, Leukemia, Lymphocytic, Chronic, B-Cell, Treatment Outcome, Drug Resistance, Neoplasm, Chromosomes, Human, Pair 2, Karyotyping, Mutation, [SDV.BBM.GTP] Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN], chronic lymphocytic leukemia, Female
Abstract

International audience; The different types of drug resistance encountered in chronic lymphocytic leukemia (CLL) cannot be fully accounted for by the 17p deletion (and/or TP53 mutation), a complex karyotype (CK), immunoglobulin heavy-chain variable region genes (IGHV) status and gene mutations. Hence, we sought to assess the associations between recurrent genomic abnormalities in CLL and the disease's development and outcome. To this end, we analyzed 64 samples from patients with CLL and gain of the short arm of chromosome 2 (2p+), which is frequent in late-stage and relapsed/refractory CLL. We found that fludarabine/cyclophosphamide/rituximab (a common first-line treatment in CLL) is not effective in removing the 2p+ clone - even in samples lacking a CK, the 17p deletion or unmutated IGHV. Our results suggest strongly that patients with CLL should be screened for 2p+ (using karyotyping and fluorescence in situ hybridization) before a treatment option is chosen. Longer follow-up is now required to evaluate bendamustine-rituximab, ibrutinib, and idelalisib-rituximab treatments.

Published
2019

29. Treatment CLL: Impact in the Dynamic of Clonal Evolution

Author

Bouzy, Simon, primary, Armand, Marine, additional, Gabillaud, Clementine, additional, Chapiro, Elise, additional, Bougacha, Nadia, additional, Kostopoulou, Fotini, additional, Davi, Frederic, additional, Le Garff-Tavernier, Magali, additional, Maloum, Karim, additional, Leblond, Veronique, additional, Morel, Veronique, additional, Roos-Weil, Damien, additional, Lavaud, Anne, additional, Gabarre, Jean, additional, Sylvain, Choquet, additional, Susin, Santos, additional, Bernard, Olivier, additional, and Nguyen-Khac, Florence, additional

Published
2018
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30. Post-Transplant Lymphoproliferative Disorders (PTLD) in Real Life: Data from the French K-Virogref Registry on 525 Adult Patients

Author

Tichadou, Antoine, Toussaint, Elise, Fornecker, Luc Matthieu, Morel, Veronique, Boussen, Inès, Roos Weil, Damien, Baron, Marine, Uzunov, Madalina, Souchet, Laetitia, Roulin, Louise, Azar, Nabih, Lepretre, Stéphane, Fontanet, Bijou, Jacquet, Caroline, Durot, Eric, Boutboul, David, Suarez, Felipe, Cluzeau, Thomas, Touati, Mohamed, Bachy, Emmanuel, Houot, Roch, Jardin, Fabrice, Guieze, Romain, Ysebaert, Loic, Farnault de Lassus, Laure, and Choquet, Sylvain

Abstract

Introduction

Published
2023
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31. A webmapping platform for publishing, sharing, and managing EO-derived data for forest protection

Author

Viergever, Karin, additional, Andrade, Pedro R., additional, Cardoso, Manoel, additional, Castillo, Miguel, additional, Exbrayat, Jean-François, additional, Middlemiss, Sarah, additional, Milodowski, David, additional, Mitchard, Edward T. A., additional, Ometto, Jean, additional, Morel, Veronique, additional, Tipper, Richard, additional, and Williams, Mathew, additional

Published
2016
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32. The Gain of the Short Arm of Chromosome 2 (2pgain) Plays an Important Role in CLL Drug Resistance, and Has to be Systematically Considered before Deciding an Adapted Therapy

Author

Kostopoulou, Fotini, Bougacha, Nadia, Gabillaud, Clementine, Chapiro, Elise, Bouzy, Simon, Le Garff-Tavernier, Magali, Maloum, Karim, Sylvain, Choquet, Leblond, Veronique, Gabarre, Jean, Lavaud, Anne, Morel, Veronique, Roos-Weil, Damien, Uzunov, Madalina, Guieze, Romain, Tournilhac, Olivier, Susin, Santos, Bernard, Olivier, and Nguyen-Khac, Florence

Published
2017
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33. The Gain of the Short Arm of Chromosome 2 (2p+) Induces XPO1 Overexpression and Drug Resistance in Chronic Lymphocytic Leukemia

Author

Cosson, Adrien, Chapiro, Elise, Lambert, Jérome, Cung, Hong-Anh, Algrin, Caroline, Damm, Frédérik, Gabillaud, Clémentine, Davi, Frederic, Merle-Béral, Hélène, Choquet, Sylvain, Uzunov, Madalina, Morel, Véronique, Leblond, Veronique, Maloum, Karim, Leprêtre, Stéphane, Feugier, Pierre, Lesty, Claude, Lejeune, Julie, Sutton, Laurent, A. Susin, Santos, and Nguyen-Khac, Florence

Published
2015
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37. Clonal Evolution in CLL

Author

Bouzy, Simon, Armand, Marine, Gabillaud, Clementine, Chapiro, Elise, Bougacha, Nadia, Kostopoulou, Fotini, Davi, Frederic, Le Garff-Tavernier, Magali, Maloum, Karim, Leblond, Veronique, Morel, Veronique, Roos-Weil, Damien, Lavaud, Anne, Gabarre, Jean, Sylvain, Choquet, Susin, Santos, Bernard, Olivier, and Nguyen-Khac, Florence

Abstract

CLL has a heterogeneous genetic landscape, and is characterized by recurrent structural abnormalities. In the era of personalized medicine, it is important to understand the role of clonal and subclonal abnormalities, their dynamic evolution and their impact on disease relapse.

Published
2017
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39. Gain of the short arm of chromosome 2 (2p gain) has a significant role in drug-resistant chronic lymphocytic leukemia.

Author

Kostopoulou F, Gabillaud C, Chapiro E, Grange B, Tran J, Bouzy S, Degaud M, Ghamlouch H, Le Garff-Tavernier M, Maloum K, Choquet S, Leblond V, Gabarre J, Lavaud A, Morel V, Roos-Weil D, Uzunov M, Guieze R, Bernard OA, Susin SA, Tournilhac O, and Nguyen-Khac F

Subjects
Adult, Aged, Antineoplastic Agents therapeutic use, Antineoplastic Combined Chemotherapy Protocols adverse effects, Antineoplastic Combined Chemotherapy Protocols therapeutic use, Chromosome Aberrations, Female, Humans, Immunoglobulin Variable Region genetics, Immunophenotyping, In Situ Hybridization, Fluorescence, Karyotyping, Leukemia, Lymphocytic, Chronic, B-Cell diagnosis, Leukemia, Lymphocytic, Chronic, B-Cell drug therapy, Leukemia, Lymphocytic, Chronic, B-Cell mortality, Longitudinal Studies, Male, Middle Aged, Mutation, Polymorphism, Single Nucleotide, Prognosis, Protein Kinase Inhibitors pharmacology, Protein Kinase Inhibitors therapeutic use, Recurrence, Time-to-Treatment, Treatment Outcome, Antineoplastic Agents pharmacology, Chromosome Duplication, Chromosomes, Human, Pair 2, Drug Resistance, Neoplasm genetics, Leukemia, Lymphocytic, Chronic, B-Cell genetics
Abstract

The different types of drug resistance encountered in chronic lymphocytic leukemia (CLL) cannot be fully accounted for by the 17p deletion (and/or TP53 mutation), a complex karyotype (CK), immunoglobulin heavy-chain variable region genes (IGHV) status and gene mutations. Hence, we sought to assess the associations between recurrent genomic abnormalities in CLL and the disease's development and outcome. To this end, we analyzed 64 samples from patients with CLL and gain of the short arm of chromosome 2 (2p+), which is frequent in late-stage and relapsed/refractory CLL. We found that fludarabine/cyclophosphamide/rituximab (a common first-line treatment in CLL) is not effective in removing the 2p+ clone - even in samples lacking a CK, the 17p deletion or unmutated IGHV. Our results suggest strongly that patients with CLL should be screened for 2p+ (using karyotyping and fluorescence in situ hybridization) before a treatment option is chosen. Longer follow-up is now required to evaluate bendamustine-rituximab, ibrutinib, and idelalisib-rituximab treatments., (© 2019 The Authors. Cancer Medicine published by John Wiley & Sons Ltd.)

Published
2019
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