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947 results on '"Moreno Mauricio"'

1. Real-time EEG-based Emotion Recognition Model using Principal Component Analysis and Tree-based Models for Neurohumanities

Author

Blanco-Rios, Miguel A., Candela-Leal, Milton O., Orozco-Romo, Cecilia, Remis-Serna, Paulina, Velez-Saboya, Carol S., Lozoya-Santos, Jorge De-J., Cebral-Loureda, Manuel, and Ramirez-Moreno, Mauricio A.

Subjects
Electrical Engineering and Systems Science - Signal Processing, Computer Science - Human-Computer Interaction, Computer Science - Machine Learning, Quantitative Biology - Neurons and Cognition
Abstract

Within the field of Humanities, there is a recognized need for educational innovation, as there are currently no reported tools available that enable individuals to interact with their environment to create an enhanced learning experience in the humanities (e.g., immersive spaces). This project proposes a solution to address this gap by integrating technology and promoting the development of teaching methodologies in the humanities, specifically by incorporating emotional monitoring during the learning process of humanistic context inside an immersive space. In order to achieve this goal, a real-time emotion detection EEG-based system was developed to interpret and classify specific emotions. These emotions aligned with the early proposal by Descartes (Passions), including admiration, love, hate, desire, joy, and sadness. This system aims to integrate emotional data into the Neurohumanities Lab interactive platform, creating a comprehensive and immersive learning environment. This work developed a ML, real-time emotion detection model that provided Valence, Arousal, and Dominance (VAD) estimations every 5 seconds. Using PCA, PSD, RF, and Extra-Trees, the best 8 channels and their respective best band powers were extracted; furthermore, multiple models were evaluated using shift-based data division and cross-validations. After assessing their performance, Extra-Trees achieved a general accuracy of 96%, higher than the reported in the literature (88% accuracy). The proposed model provided real-time predictions of VAD variables and was adapted to classify Descartes' six main passions. However, with the VAD values obtained, more than 15 emotions can be classified (reported in the VAD emotion mapping) and extend the range of this application., Comment: 20 pages, 7 figures. Submitted to Frontiers in Human Neuroscience

Published
2024
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2. Chromosome-level assembly of the gray fox (Urocyon cinereoargenteus) confirms the basal loss of PRDM9 in Canidae.

Author

Armstrong, Ellie, Bissell, Ky, Fatima, H, Heikkinen, Maya, Jessup, Anika, Junaid, Maryam, Lee, Dong, Lieb, Emily, Liem, Josef, Martin, Estelle, Moreno, Mauricio, Otgonbayar, Khuslen, Romans, Betsy, Royar, Kim, Adler, Mary, Needle, David, Harkess, Alex, Kelley, Joanna, Mooney, Jazlyn, and Mychajliw, Alexis

Subjects
Canidae, PRDM9, gray fox, heterozygosity, Animals, Foxes, Phylogeny, Chromosomes, DNA, Mitochondrial, Genome
Abstract

Reference genome assemblies have been created from multiple lineages within the Canidae family; however, despite its phylogenetic relevance as a basal genus within the clade, there is currently no reference genome for the gray fox (Urocyon cinereoargenteus). Here, we present a chromosome-level assembly for the gray fox (U. cinereoargenteus), which represents the most contiguous, non-domestic canid reference genome available to date, with 90% of the genome contained in just 34 scaffolds and a contig N50 and scaffold N50 of 59.4 and 72.9 Megabases, respectively. Repeat analyses identified an increased number of simple repeats relative to other canids. Based on mitochondrial DNA, our Vermont sample clusters with other gray fox samples from the northeastern United States and contains slightly lower levels of heterozygosity than gray foxes on the west coast of California. This new assembly lays the groundwork for future studies to describe past and present population dynamics, including the delineation of evolutionarily significant units of management relevance. Importantly, the phylogenetic position of Urocyon allows us to verify the loss of PRDM9 functionality in the basal canid lineage, confirming that pseudogenization occurred at least 10 million years ago.

Published
2024

24. Myocutaneous Rectus-Free Flap

Author

Moreno, Mauricio A., Stack, Brendan C., Jr, Stack Jr., Brendan C., editor, Moreno, Mauricio A., editor, Boyette, Jennings R., editor, and Vural, Emre A., editor

Published
2023
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48. Spinal cord regeneration in Xenopus tadpoles proceeds through activation of Sox2-positive cells

Author

Gaete Marcia, Muñoz Rosana, Sánchez Natalia, Tampe Ricardo, Moreno Mauricio, Contreras Esteban G, Lee-Liu Dasfne, and Larraín Juan

Subjects
Spinal cord regeneration, Sox2, Xenopus, Neurology. Diseases of the nervous system, RC346-429
Abstract

Abstract Background In contrast to mammals, amphibians, such as adult urodeles (for example, newts) and anuran larvae (for example, Xenopus) can regenerate their spinal cord after injury. However, the cellular and molecular mechanisms involved in this process are still poorly understood. Results Here, we report that tail amputation results in a global increase of Sox2 levels and proliferation of Sox2+ cells. Overexpression of a dominant negative form of Sox2 diminished proliferation of spinal cord resident cells affecting tail regeneration after amputation, suggesting that spinal cord regeneration is crucial for the whole process. After spinal cord transection, Sox2+ cells are found in the ablation gap forming aggregates. Furthermore, Sox2 levels correlated with regenerative capabilities during metamorphosis, observing a decrease in Sox2 levels at non-regenerative stages. Conclusions Sox2+ cells contribute to the regeneration of spinal cord after tail amputation and transection. Sox2 levels decreases during metamorphosis concomitantly with the lost of regenerative capabilities. Our results lead to a working hypothesis in which spinal cord damage activates proliferation and/or migration of Sox2+ cells, thus allowing regeneration of the spinal cord after tail amputation or reconstitution of the ependymal epithelium after spinal cord transection.

Published
2012
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