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1. The developmental roots of neurodegeneration

Author

Morgan C. Stephens, Vicky Brandt, and Juan Botas

Subjects
Neurons, Huntington Disease, General Neuroscience, Humans, Neurodegenerative Diseases
Abstract

Neurodegenerative disorders can alter neural circuitry long before symptoms appear, but the path from early changes to later pathologies is obscure. In this issue of Neuron, Capizzi et al. (2021) show how early axonal growth defects in Huntington's disease create vulnerability to later degeneration.

Published
2022

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