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124 results on '"Moriyama, Yasushi"'

12. Dysconnectivity of the Agency Network in Schizophrenia: A Functional Magnetic Resonance Imaging Study

Author

Koreki, Akihiro, primary, Maeda, Takaki, additional, Okimura, Tsukasa, additional, Terasawa, Yuri, additional, Kikuchi, Toshiaki, additional, Umeda, Satoshi, additional, Nishikata, Shiro, additional, Yagihashi, Tatsuhiko, additional, Kasahara, Mari, additional, Nagai, Chiyoko, additional, Moriyama, Yasushi, additional, Den, Ryosuke, additional, Watanabe, Tamotsu, additional, Kikumoto, Hirotsugu, additional, Kato, Motoichiro, additional, and Mimura, Masaru, additional

Published
2019
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15. Insulin resistance and endothelial dysfunction in smokers: effects of vitamin C

Author

HIRAI, NOBUTAKA, KAWANO, HIROAKI, HIRASHIMA, OSAMU, MOTOYAMA, TAKESHI, MORIYAMA, YASUSHI, SAKAMOTO, TOMOHIRO, KUGIYAMA, KIYOTAKA, OGAWA, HISAO, NAKAO, KAZUWA, and YASUE, HIROFUMI

Subjects
Oxidation, Physiological -- Research, Smoking -- Research, Insulin -- Research, Endothelin -- Research, Biological sciences
Abstract

Insulin resistance and endothelial dysfunction in smokers: effects of vitamin C. Am J Physiol Heart Circ Physiol 279: H1172-H1178, 2000.--Cigarette smoking impairs endothelial function and is one of the major risk factors for atherosclerosis and coronary heart disease. Insulin resistance is associated with major risk factors for atherosclerosis. We examined the effects of vitamin C on insulin sensitivity and endothelial function by measuring steady-state plasma glucose (SSPG) and flow-mediated dilation (FMD) of the brachial artery. We studied 16 current smokers with normal glucose tolerance, 15 nonsmokers with impaired glucose tolerance (IGT), and 17 nonsmokers with normal glucose tolerance as controls. Both SSPG and FMD were blunted in smokers and nonsmokers with IGT compared with controls. In smokers, vitamin C decreased SSPG (P [is less than] 0.01 by ANOVA) with decreasing plasma thiobarbituric acid-reactive substances (TBARS) (P [is less than] 0.05 by ANOVA) and improved FMD (P [is less than] 0.05 by ANOVA). Furthermore, vitamin C improved both SSPG (P [is less than] 0.005 by ANOVA) and FMD (P [is less than] 0.05 by ANOVA) in nonsmokers with IGT. SSPG, FMD, or TBARS in controls did not change after vitamin C infusion. There was a significant correlation between SSPG and FMD both in smokers and nonsmokers with IGT, whereas no correlation was observed in controls. In conclusion, both insulin sensitivity and endothelial function were impaired in smokers and nonsmokers with IGT and were improved by vitamin C. Thus increased reactive oxygen species play an important role in the pathogenesis of insulin resistance as well as endothelial dysfunction in smokers and nonsmokers with IGT. oxidative stress; cigarette smoking; insulin sensitivity; endothelial function

Published
2000

20. Detailed analysis of error patterns in the number-transcoding task on the Japanese version of the Rapid Dementia Screening Test.

Author

Moriyama, Yasushi, Yoshino, Aihide, Muramatsu, Taro, and Mimura, Masaru

Subjects
*ALZHEIMER'S disease, *MATHEMATICS, *NEUROPSYCHOLOGICAL tests, *RESEARCH methodology evaluation, *MEDICAL coding, *PSYCHOLOGY
Abstract

Aim The number-transcoding task on the Japanese version of the Rapid Dementia Screening Test requires mutual conversion between Arabic and Chinese numerals (e.g. 209 → 二百九, 4054 → 四千五十四, 六百八十一 → 681, 二千二十七 → 2027). During this task, some characteristic errors have been seen among patients with Alzheimer's disease ( AD). The objective of this study was to clarify whether the frequency of appearance of error patterns differs between patients with mild and severe AD according to Clinical Dementia Rating ( CDR) scores. Methods A total of 250 patients with AD were recruited and subsequently categorized into two groups based on CDR scores (mild AD: CDR of 0.5 or 1; severe AD: CDR of 2 or 3). We analyzed 19 qualitative error patterns, including 15 that had been reported to date and 4 previously unreported errors, in each subtest. Results The frequency of appearance of two previously reported and four previously unreported errors in the mild and severe AD groups, respectively, were statistically significant. Conclusions Characteristic error pattern distributions in number transcoding can be observed in patients with mild and severe AD according to CDR scores and offers useful information for interpreting cognitive screening data. [ABSTRACT FROM AUTHOR]

Published
2017
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21. Detailed analysis of the supermarket task included on the Japanese version of the Rapid Dementia Screening Test.

Author

Moriyama, Yasushi, Yoshino, Aihide, Muramatsu, Taro, and Mimura, Masaru

Subjects
*ALZHEIMER'S disease, *CLUSTER analysis (Statistics), *DEMENTIA, *NEUROPSYCHOLOGICAL tests, *QUESTIONNAIRES, *STATISTICS, *DATA analysis, *SEVERITY of illness index, *RESEARCH methodology evaluation, *EVALUATION
Abstract

Aim The supermarket task, which is included in the Japanese version of the Rapid Dementia Screening Test, requires the quick (1 min) generation of words for things that can be bought in a supermarket. Cluster size and switches are investigated during this task. We investigated how the severity of dementia related to cluster size and switches on the supermarket task in patients with Alzheimer's disease. Methods We administered the Japanese version of the Rapid Dementia Screening Test to 250 patients with very mild to severe Alzheimer's disease and to 49 healthy volunteers. Patients had Mini- Mental State Examination scores from 12 to 26 and Clinical Dementia Rating scale scores from 0.5 to 3. Patients were divided into four groups based on their Clinical Dementia Rating score (0.5, 1, 2, 3). We performed statistical analyses between the four groups and control subjects based on cluster size and switch scores on the supermarket task. Results The score for cluster size and switches deteriorated according to the severity of dementia. Moreover, for subjects with a Clinical Dementia Rating score of 0.5, cluster size was impaired, but switches were intact. Conclusions Our findings indicate that the scores for cluster size and switches on the supermarket task may be useful for detecting the severity of symptoms of dementia in patients with Alzheimer's disease. [ABSTRACT FROM AUTHOR]

Published
2017
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23. The Japanese version of the Rapid Dementia Screening Test is effective compared to the clock-drawing test for detecting patients with mild Alzheimer's disease.

Author

Moriyama, Yasushi, Yoshino, Aihide, Yamanaka, Kaori, Kato, Motoichiro, Muramatsu, Taro, and Mimura, Masaru

Subjects
*ALZHEIMER'S disease, *NEUROPSYCHOLOGICAL tests, *RESEARCH methodology, *QUESTIONNAIRES, *RESEARCH methodology evaluation, *ONE-way analysis of variance
Abstract

The article presents a study on the Japanese version of the Rapid Dementia Screening Test (RDST-J), and its efficacy compared to the clock-drawing test (CDT) as brief psychometric screening tools for the severity of Alzheimer's disease. Topics include assessments using the Mini-Mental State Examination and Clinical Dementia Rating (CDR), their relative sensitivity and specificity, and results of the study showing that the RDST-J is more effective in distinguishing CDR 0.5 from controls.

Published
2016
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39. Circulating Levels of Secretory Type II Phospholipase A 2 Predict Coronary Events in Patients with Coronary Artery Disease

Author

Kugiyama, Kiyotaka, primary, Ota, Yasutaka, additional, Takazoe, Keiji, additional, Moriyama, Yasushi, additional, Kawano, Hiroaki, additional, Miyao, Yuji, additional, Sakamoto, Tomohiro, additional, Soejima, Hirofumi, additional, Ogawa, Hisao, additional, Doi, Hideki, additional, Sugiyama, Seigo, additional, and Yasue, Hirofumi, additional

Published
1999
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40. Improvement of endothelial vasomotor dysfunction by treatment with alpha-tocopherol in patients with high remnant lipoproteins levels

Author

Kugiyama, Kiyotaka, primary, Motoyama, Takeshi, additional, Doi, Hideki, additional, Kawano, Hiroaki, additional, Hirai, Nobutaka, additional, Soejima, Hirofumi, additional, Miyao, Yuji, additional, Takazoe, Keiji, additional, Moriyama, Yasushi, additional, Mizuno, Yuji, additional, Tsunoda, Ryusuke, additional, Ogawa, Hisao, additional, Sakamoto, Tomohiro, additional, Sugiyama, Seigo, additional, and Yasue, Hirofumi, additional

Published
1999
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42. Vitamin E administration improves impairment of endothelium-dependent vasodilation in patients with coronary spastic angina

Author

Motoyama, Takeshi, primary, Kawano, Hiroaki, additional, Kugiyama, Kiyotaka, additional, Hirashima, Osamu, additional, Ohgushi, Masamichi, additional, Tsunoda, Ryusuke, additional, Moriyama, Yasushi, additional, Miyao, Yuji, additional, Yoshimura, Michihiro, additional, Ogawa, Hisao, additional, and Yasue, Hirofumi, additional

Published
1998
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43. Relationship between serum angiotensin-converting enzyme activity and plasma plasminogen activator inhibitor activity in patients with recent myocardial infarction

Author

Moriyama, Yasushi, primary, Ogawa, Hisao, additional, Oshima, Shuichi, additional, Arai, Hidekazu, additional, Takazoe, Keiji, additional, Shimomura, Hideki, additional, Hirai, Nobutaka, additional, Suefuji, Hisakazu, additional, Soejima, Hirofumi, additional, Nishiyama, Koichi, additional, Misumi, Kenji, additional, and Yasue, Hirofumi, additional

Published
1998
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44. Serial Changes in Plasma Levels of Soluble P-Selectin in Patients With Acute Myocardial Infarction

Author

Shimomura, Hideki, primary, Ogawa, Hisao, additional, Arai, Hidekazu, additional, Moriyama, Yasushi, additional, Takazoe, Keiji, additional, Hirai, Nobutaka, additional, Kaikita, Koichi, additional, Hirashima, Osamu, additional, Misumi, Kenji, additional, Soejima, Hirofumi, additional, Nishiyama, Koichi, additional, and Yasue, Hirofumi, additional

Published
1998
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45. Captopril Reduced Plasminogen Activator Inhibitor Activity in Patients With Acute Myocardial Infarction

Author

Moriyama, Yasushi, primary, Ogawa, Hisao, additional, Oshima, Shuich, additional, Takazoe, Keiji, additional, Honda, Yoshio, additional, Hirashima, Osamu, additional, Arai, Hidekazu, additional, Sakamoto, Tomohiro, additional, Sumida, Hitoshi, additional, Suefuji, Hisakazu, additional, Kaikita, Koichi, additional, and Yasue, Hirofumi, additional

Published
1997
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49. Identification of an alkaliphilic actinomycetes that produces a PrPSc-degrading enzyme.

Author

Mitsuiki, Shinji, Takasugi, Mikako, Moriyama, Yasushi, Futagami, Taiki, Goto, Masatoshi, Kanouchi, Hiroaki, and Oka, Tatsuzo

Abstract

An alkaliphilic actinomycete strain TOA-1, that produces a PrPSc-degrading keratinase, was isolated from cement of bathroom tiles. This strain produced substrate and aerial mycelia. Growth occurred in the pH range 7.5–13.0, with an optimal pH of 10.0. A salt concentration of up to 8% was tolerated, and various organic substrates were used for growth. Strain TOA-1 contained meso-diaminopimelic acid, no diagnostic sugars, iso-C16:0 as the major cellular fatty acid, and MK-10, MK-10(H2), and MK-10(H4) as the predominant menaquinones. The G+C content was 71 mol%. All these characteristics, together with an analysis of its phylogenetic position, indicated that this strain belongs to the genus Nocardiopsis. DNA–DNA hybridization with its closest relative N. metallicus indicated a similarity of 55%, which suggested that strain TOA-1, deposited in the International Patent Organism Depositary National Institute of Advanced Industrial Science and Technology (FERM BP-08603) in Japan as a patent strain, represents a novel species of the genus Nocardiopsis. [ABSTRACT FROM AUTHOR]

Published
2010
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