48 results on '"Morretta, Elva"'
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2. Development of dual GPBAR1 agonist and RORγt inverse agonist for the treatment of inflammatory bowel diseases
3. H3K56 acetylation affects Candida albicans morphology and secreted soluble factors interacting with the host
4. High levels of soluble CD73 unveil resistance to BRAF inhibitors in melanoma cells
5. Combinatorial therapy with BAR502 and UDCA resets FXR and GPBAR1 signaling and reverses liver histopathology in a model of NASH
6. Bile acids serve as endogenous antagonists of the Leukemia inhibitory factor (LIF) receptor in oncogenesis
7. Activation of GPBAR1 attenuates vascular inflammation and atherosclerosis in a mouse model of NAFLD-related cardiovascular disease
8. A multidisciplinary functional proteomics-aided strategy as a tool for the profiling of a novel cytotoxic thiadiazolopyrimidone
9. Design, Synthesis, and Pharmacological Evaluation of Dual FXR-LIFR Modulators for the Treatment of Liver Fibrosis.
10. Synthesis, functional proteomics and biological evaluation of new 5-pyrazolyl ureas as potential anti-angiogenic compounds
11. A microbial derived bile acid acts as GPBAR1 agonist and RORγt inverse agonist and reverses inflammation in inflammatory bowel disease
12. Analysis of Hsp90 allosteric modulators interactome reveals a potential dual action mode involving mitochondrial MDH2
13. Novel insights on the molecular mechanism of action of the anti-angiogenic pyrazolyl-urea GeGe-3 by functional proteomics
14. Identification of Mortalin as the Main Interactor of Mycalin A, a Poly-Brominated C-15 Acetogenin Sponge Metabolite, by MS-Based Proteomics
15. Defective Bile Acid Signaling Promotes Vascular Dysfunction, Supporting a Role for G‐Protein Bile Acid Receptor 1/Farnesoid X Receptor Agonism and Statins in the Treatment of Nonalcoholic Fatty Liver Disease
16. The leukemia inhibitory factor regulates fibroblast growth factor receptor 4 transcription in gastric cancer
17. Bile Acids Serve As Endogenous Antagonists Of The Leukemia Inhibitory Factor (LIF) Receptor in Oncogenesis
18. Serum Bile Acid Levels Before and After Sleeve Gastrectomy and Their Correlation with Obesity-Related Comorbidities
19. Identification of a Protein Arginine Methyltransferase 7 (PRMT7)/Protein Arginine Methyltransferase 9 (PRMT9) Inhibitor
20. Targeting USP-7 by a Novel Fluorinated 5-Pyrazolyl-Urea Derivative
21. Discovery of BAR502, as potent steroidal antagonist of leukemia inhibitory factor receptor for the treatment of pancreatic adenocarcinoma
22. Curcumin Has Beneficial Effects on Lysosomal Alpha-Galactosidase: Potential Implications for the Cure of Fabry Disease
23. Repositioning Mifepristone as a Leukaemia Inhibitory Factor Receptor Antagonist for the Treatment of Pancreatic Adenocarcinoma
24. Beneficial effects of UDCA and norUDCA in a rodent model of steatosis are linked to modulation of GPBAR1/FXR signaling
25. Role of Intracellular and Extracellular Annexin A1 in MIA PaCa-2 Spheroids Formation and Drug Sensitivity
26. Drug affinity-responsive target stability unveils filamins as biological targets for artemetin, an anti-cancer flavonoid
27. Drug Repositioning for Fabry Disease: Acetylsalicylic Acid Potentiates the Stabilization of Lysosomal Alpha-Galactosidase by Pharmacological Chaperones
28. Exosomal CD73 from serum of patients with melanoma suppresses lymphocyte functions and is associated with therapy resistance to anti-PD-1 agents
29. Su1492 BILE ACIDS AS ENDOGENOUS ANTAGONISTS OF LEUKEMIA INHIBITORY FACTOR RECEPTOR (LIFR) IN GASTRIC CANCER (GC): IMPLICATIONS FOR THERAPEUTIC INTERVENTIONS
30. 913 THE BILE ACIDS METABOLITES PRODUCED BY THE INTESTINAL MICROBIOTA ACT AS GPBAR1 AGONIST AND RORΓT INVERSE AGONIST DETERMINING THE COURSE OF INFLAMMATORY BOWEL DISEASE
31. Label-Free Quantitative Proteomics to Explore the Action Mechanism of the Pharmaceutical-Grade Triticum vulgare Extract in Speeding Up Keratinocyte Healing
32. Atorvastatin protects against liver and vascular damage in a model of diet induced steatohepatitis by resetting FXR and GPBAR1 signaling
33. The Pyrazolyl-Urea Gege3 Inhibits the Activity of ANXA1 in the Angiogenesis Induced by the Pancreatic Cancer Derived EVs
34. Label-Free Quantitative Proteomics To Explore The Action Mechanism of The Pharmaceutical Grade Triticum Vulgare Extract In Speeding Up Keratinocytes Healing.
35. Involvement of 3′,5′‐cyclic inosine monophosphate in cystathionine γ‐lyase‐dependent regulation of the vascular tone
36. RETRACTED: Mesoglycan exerts its fibrinolytic effect through the activation of annexin A2
37. Serum CD73 is a prognostic factor in patients with metastatic melanoma and is associated with response to anti-PD-1 therapy
38. Mo1801 BILE ACID METABOLITES REGULATE INTESTINAL IMMUNITY BY ACTING AS GPBAR1 AGONIST AND RORΓT INVERSE AGONIST MODULATING THE BALANCE OF TH17/TREG AND M1/M2 MACROPHAGES
39. 217 BAR502, A DUAL FXR AND GPBAR1 AGONIST, SYNERGIZED ATORVASTATIN BENEFICIAL EFFECTS ON VASCULAR INFLAMMATION IN NASH
40. Opposite effects of the FXR agonist obeticholic acid on Mafg and Nrf2 mediate the development of acute liver injury in rodent models of cholestasis
41. Carbamoyl-Phosphate Synthase 1 as a Novel Target of Phomoxanthone A, a Bioactive Fungal Metabolite
42. Crellastatin A, a PARP‐1 Inhibitor Discovered by Complementary Proteomic Approaches
43. Atorvastatin protects against liver and vascular damage in a model of diet induced steatohepatitis by resetting FXR and GPBAR1 signaling.
44. Mesoglycan exerts its fibrinolytic effect through the activation of annexin A2.
45. Transcriptome Analysis of Dual FXR and GPBAR1 Agonism in Rodent Model of NASH Reveals Modulation of Lipid Droplets Formation
46. Discovering the Biological Target of 5-epi-Sinuleptolide Using a Combination of Proteomic Approaches
47. Repositioning Mifepristone as a Leukaemia Inhibitory Factor Receptor Antagonist for the Treatment of Pancreatic Adenocarcinoma
48. Drug Repositioning for Fabry Disease: Acetylsalicylic Acid Potentiates the Stabilization of Lysosomal Alpha-Galactosidase by Pharmacological Chaperones
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