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Introduction: When discussing cytotoxic chemotherapy, the way the drugs are administered is as important as choosing the regimen. Several aspects like hyperhydration, emesis, the period of administration, diet and allergic reactions have to be taken into consideration. Method: Recent literature on these five main topics was revised. Most relevant data was collected and summarized in an attempt to familiarize any reader with this matter. Conclusion:These aspects are of utmost importance in reducing toxicity, thus enabling more extended treatment compliance, administration of effective doses and better oncological outcomes. [ABSTRACT FROM AUTHOR]

Introduction: When discussing cytotoxic chemotherapy, the way the drugs are administered is as important as choosing the regimen. Several aspects like hyperhydration, emesis, the period of administration, diet and allergic reactions have to be taken into consideration. Method: Recent literature on these fi ve main topics was revised. Most relevant data was collected and summarized in an attempt to familiarize any reader with this matter. Conclusion:These aspects are of utmost importance in reducing toxicity, thus enabling more extended treatment compliance, administration of effective doses and better oncological outcomes. [ABSTRACT FROM AUTHOR]