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29 results on '"Mouratidis, Petros"'

1. Complementary techniques for the reliable characterisation of tissue samples: A case study on pancreatic tumours analysed by means of X-ray fluorescence analysis and IR spectroscopy.

Author

Frenzel, Katja, Kayser, Yves, Hornemann, Andrea, Kästner, Bernd, Hoehl, Arne, Mouratidis, Petros, Rivens, Ian, ter Haar, Gail, and Beckhoff, Burkhard

Subjects
X-ray absorption near edge structure, X-ray spectroscopy, DNA fingerprinting, PANCREATIC duct, TREATMENT effectiveness
Abstract

An improvement in the reliability and comparability of tissue characterization results is crucial for enabling further progress in cancer detection and the assessment of therapeutic effects. This can only be achieved by integrating quantitative methods into well-established qualitative characterization routines. This case study presents a hybrid metrological approach for tissue characterisation including vibrational Fourier Transform InfraRed (FTIR) spectroscopy and traceable reference-free X-Ray Fluorescence analysis (XRF). Through the combination of spatially resolved qualitative molecular information with quantitative elemental concentrations an all-encompassing sample characterisation can be provided. The study was performed on tissue sections of syngeneic murine pancreatic ductal adenocarcinoma KPC (KrasG12D/+; Trp53R172H/+; Pdx-1-Cre) tumours ex-vivo. Sections from healthy pancreatic tissues, sham-exposed tumours and tumours subjected to low dose radiotherapy treatment (2 Gray and 6 Gray) were analysed using both methods. Additional sample integrity studies using Near Edge X-ray Absorption Fine Structure (NEXAFS) spectroscopy at the carbon and nitrogen K-edges were performed to assess the effect of sample aging and XRF investigations on the samples. Results showed an increase in the concentrations of elemental biomarkers, including S, K and amide I structures in malignant pancreatic tissue compared to healthy pancreatic tissue. The exposure of tumours to 6 Gy radiation decreases the levels of these elements towards a phenotype seen in the healthy pancreas. A protocol for hybrid investigations is presented, with emphasis on the sample preparation, minimizing the impact of consecutive applied methods on their measurands, and ensuring the compatibility and reliability of achieved results. The study demonstrates the cancer recognition capabilities, and the sensitivity for low dosage radiotherapy treatment monitoring for each method individually and assesses the potential of combining molecular fingerprinting with non-destructive quantitative elemental information for tissue sample characterization. [ABSTRACT FROM AUTHOR]

Published
2024
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6. Focused Ultrasound-Mediated Hyperthermia in Vitro: An Experimental Arrangement for Treating Cells under Tissue-Mimicking Conditions

Author

Brüningk, Sarah C., Rivens, Ian, Mouratidis, Petros, and ter Haar, Gail

Subjects
In vitro, Focused ultrasound, High-intensity focused ultrasound, Phantoms, Imaging, Tissue mimic, High-Intensity Focused Ultrasound Ablation, Hyperthermia, Hyperthermia, Induced, In Vitro Techniques, Article
Abstract

An experimental arrangement that allows in vitro exposure of cells to focused ultrasound-mediated hyperthermia (43°C–55°C) in a tissue-mimicking phantom with biological, acoustic and thermal properties comparable to those of human soft tissue is described. Cells were embedded in a compressed collagen gel, which was sandwiched between 6-mm-thick slices of biocompatible, acoustically absorbing and thermally tissue mimicking poly(vinyl alcohol) cryo-gel. To illustrate the system's potential, cells were exposed using a 1.66-MHz focused ultrasound beam (spatial-peak temporal-average intensities (ISPTA) = 900–1400 W/cm2) that traced out a circular trajectory (5–8 mm in diameter). Real-time temperature monitoring allowed cells to be exposed reproducibly to a pre-determined thermal dose. An experimental planning tool that estimates the thermal dose distribution throughout the sample and allows spatial correlation with cell position has been developed. Treatment response was evaluated qualitatively using microscopy and cell viability testing. This experimental arrangement has significant potential for future, biologically relevant, in vitro focused ultrasound-mediated hyperthermia studies.

Published
2019

7. Supplement from Pulsed focused ultrasound can improve the anti-cancer effects of immune checkpoint inhibitors in murine pancreatic cancer

Author

Mouratidis, Petros X. E., Costa, Marcia, Rivens, Ian, Repasky, Elizabeth E., and ter Haar, Gail

Abstract

Pulsed high-intensity focused ultrasound (pHIFU) uses acoustic pressure to physically disrupt tumours. The aim of this study was to investigate whether pHIFU can be used in combination with immune checkpoint inhibitors (ICIs) to enhance survival of tumour-bearing animals. Murine orthotopic pancreatic KPC tumours were exposed both to a grid of pHIFU lesions (peak negative pressure = 17 MPa, frequency = 1.5 MHz, duty cycle = 1%, 1 pulse s−1, duration = 25 s) and to anti-CTLA-4/anti-PD-1 antibodies. Acoustic cavitation was detected using a weakly focused passive sensor. Tumour dimensions were measured with B-mode ultrasound before treatment and with callipers post-mortem. Immune cell subtypes were quantified with immunohistochemistry and flow cytometry. pHIFU treatment of pancreatic tumours resulted in detectable acoustic cavitation and increased infiltration of CD8+ T cells in the tumours of pHIFU and pHIFU + ICI-treated subjects compared to sham-exposed subjects. Survival of subjects treated with pHIFU + ICI was extended relative to both control untreated subjects and those treated with either pHIFU or ICI alone. Subjects treated with pHIFU + ICI had increased levels of CD8+IFNγ+ T cells, increased ratios of CD8+IFNγ+ to CD3+CD4+FoxP3+ and CD11b+Ly6G+ cells, and decreased CD11chigh cells in their tumours compared to controls. These results provide evidence that pHIFU combined with ICI may have potential for use in pancreatic cancer therapy.

Published
2021
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12. International Society for Therapeutic Ultrasound Conference 2016

Author

Fowlkes, Brian, Ghanouni, Pejman, Sanghvi, Narendra, Coussios, Constantin, Lyon, Paul C., Gray, Michael, Mannaris, Christophoros, Victor, Marie de Saint, Stride, Eleanor, Cleveland, Robin, Carlisle, Robert, Wu, Feng, Middleton, Mark, Gleeson, Fergus, Aubry, Jean-Franҫois, Pauly, Kim Butts, Moonen, Chrit, Vortman, Jacob, Sharabi, Shirley, Daniels, Dianne, Last, David, Guez, David, Levy, Yoav, Volovick, Alexander, Grinfeld, Javier, Rachmilevich, Itay, Amar, Talia, Zibly, Zion, Mardor, Yael, Harnof, Sagi, Plaksin, Michael, Weissler, Yoni, Shoham, Shy, Kimmel, Eitan, Naor, Omer, Farah, Nairouz, Paeng, Dong-Guk, Xu, Zhiyuan, Snell, John, Quigg, Anders H., Eames, Matthew, Jin, Changzhu, Everstine, Ashli C., Sheehan, Jason P., Lopes, Beatriz S., Kassell, Neal, Looi, Thomas, Khokhlova, Vera, Mougenot, Charles, Hynynen, Kullervo, Drake, James, Slayton, Michael, Amodei, Richard C., Compton, Keegan, McNelly, Ashley, Latt, Daniel, Kearney, John, Melodelima, David, Dupre, Aurelien, Chen, Yao, Perol, David, Vincenot, Jeremy, Chapelon, Jean-Yves, Rivoire, Michel, Guo, Wei, Ren, Guoxin, Shen, Guofeng, Neidrauer, Michael, Zubkov, Leonid, Weingarten, Michael S., Margolis, David J., Lewin, Peter A., McDannold, Nathan, Sutton, Jonathan, Vykhodtseva, Natalia, Livingstone, Margaret, Kobus, Thiele, Zhang, Yong-Zhi, Schwartz, Michael, Huang, Yuexi, Lipsman, Nir, Jain, Jennifer, Chapman, Martin, Sankar, Tejas, Lozano, Andres, Yeung, Robert, Damianou, Christakis, Papadopoulos, Nikolaos, Brokman, Omer, Zadicario, Eyal, Brenner, Ori, Castel, David, Wu, Shih-Ying, Grondin, Julien, Zheng, Wenlan, Heidmann, Marc, Karakatsani, Maria Eleni, Sánchez, Carlos J. Sierra, Ferrera, Vincent, Konofagou, Elisa E., Yiannakou, Marinos, Cho, HongSeok, Lee, Hwayoun, Han, Mun, Choi, Jong-Ryul, Lee, Taekwan, Ahn, Sanghyun, Chang, Yongmin, Park, Juyoung, Ellens, Nicholas, Partanen, Ari, Farahani, Keyvan, Airan, Raag, Carpentier, Alexandre, Canney, Michael, Vignot, Alexandre, Lafon, Cyril, Delattre, Jean-yves, Idbaih, Ahmed, Odéen, Henrik, Bolster, Bradley, Jeong, Eun Kee, Parker, Dennis L., Gaur, Pooja, Feng, Xue, Fielden, Samuel, Meyer, Craig, Werner, Beat, Grissom, William, Marx, Michael, Weber, Hans, Taviani, Valentina, Hargreaves, Brian, Tanaka, Jun, Kikuchi, Kentaro, Ishijima, Ayumu, Azuma, Takashi, Minamihata, Kosuke, Yamaguchi, Satoshi, Nagamune, Teruyuki, Sakuma, Ichiro, Takagi, Shu, Santin, Mathieu D., Marsac, Laurent, Maimbourg, Guillaume, Monfort, Morgane, Larrat, Benoit, François, Chantal, Lehéricy, Stéphane, Tanter, Mickael, Samiotaki, Gesthimani, Wang, Shutao, Acosta, Camilo, Feinberg, Eliza R., Kovacs, Zsofia I., Tu, Tsang-Wei, Papadakis, Georgios Z., Reid, William C., Hammoud, Dima A., Frank, Joseph A., Kovacs, Zsofia i., Kim, Saejeong, Jikaria, Neekita, Bresler, Michele, Qureshi, Farhan, Xia, Jingjing, Tsui, Po-Shiang, Liu, Hao-Li, Plata, Juan C., Sveinsson, Bragi, Salgaonkar, Vasant A., Adams, Matthew, Diederich, Chris, Ozhinsky, Eugene, Bucknor, Matthew D., Rieke, Viola, Mikhail, Andrew, Severance, Lauren, Negussie, Ayele H., Wood, Bradford, de Greef, Martijn, Schubert, Gerald, Ries, Mario, Poorman, Megan E., Dockery, Mary, Chaplin, Vandiver, Dudzinski, Stephanie O., Spears, Ryan, Caskey, Charles, Giorgio, Todd, Costa, Marcia M., Papaevangelou, Efthymia, Shah, Anant, Rivens, Ian, Box, Carol, Bamber, Jeff, ter Haar, Gail, Burks, Scott R., Nagle, Matthew, Nguyen, Ben, Milo, Blerta, Le, Nhan M., Song, Shaozhen, Zhou, Kanheng, Nabi, Ghulam, Huang, Zhihong, Ben-Ezra, Shmuel, Rosen, Shani, Mihcin, Senay, Strehlow, Jan, Karakitsios, Ioannis, Le, Nhan, Schwenke, Michael, Demedts, Daniel, Prentice, Paul, Haase, Sabrina, Preusser, Tobias, Melzer, Andreas, Mestas, Jean-Louis, Chettab, Kamel, Gomez, Gustavo Stadthagen, Dumontet, Charles, Werle, Bettina, Marquet, Fabrice, Bour, Pierre, Vaillant, Fanny, Amraoui, Sana, Dubois, Rémi, Ritter, Philippe, Haïssaguerre, Michel, Hocini, Mélèze, Bernus, Olivier, Quesson, Bruno, Livneh, Amit, Adam, Dan, Robin, Justine, Arnal, Bastien, Fink, Mathias, Pernot, Mathieu, Khokhlova, Tatiana D., Schade, George R., Wang, Yak-Nam, Kreider, Wayne, Simon, Julianna, Starr, Frank, Karzova, Maria, Maxwell, Adam, Bailey, Michael R., Lundt, Jonathan E., Allen, Steven P., Sukovich, Jonathan R., Hall, Timothy, Xu, Zhen, May, Philip, Lin, Daniel W., Constans, Charlotte, Deffieux, Thomas, Aubry, Jean-Francois, Park, Eun-Joo, Ahn, Yun Deok, Kang, Soo Yeon, Park, Dong-Hyuk, Lee, Jae Young, Vidal-Jove, J., Perich, E., Ruiz, A., Jaen, A., Eres, N., del Castillo, M. Alvarez, Myers, Rachel, Kwan, James, Coviello, Christian, Rowe, Cliff, Crake, Calum, Finn, Sean, Jackson, Edward, Pouliopoulos, Antonios, Li, Caiqin, Tinguely, Marc, Tang, Meng-Xing, Garbin, Valeria, Choi, James J., Folkes, Lisa, Stratford, Michael, Nwokeoha, Sandra, Li, Tong, Farr, Navid, D’Andrea, Samantha, Gravelle, Kayla, Chen, Hong, Lee, Donghoon, Hwang, Joo Ha, Tardoski, Sophie, Ngo, Jacqueline, Gineyts, Evelyne, Roux, Jean-Pau, Clézardin, Philippe, Conti, Allegra, Magnin, Rémi, Gerstenmayer, Matthieu, Lux, François, Tillement, Olivier, Mériaux, Sébastien, Penna, Stefania Della, Romani, Gian Luca, Dumont, Erik, Sun, Tao, Power, Chanikarn, Miller, Eric, Sapozhnikov, Oleg, Tsysar, Sergey, Yuldashev, Petr V., Svet, Victor, Li, Dongli, Pellegrino, Antonio, Petrinic, Nik, Siviour, Clive, Jerusalem, Antoine, Yuldashev, Peter V., Cunitz, Bryan W., Dunmire, Barbrina, Inserra, Claude, Guedra, Matthieu, Mauger, Cyril, Gilles, Bruno, Solovchuk, Maxim, Sheu, Tony W. H., Thiriet, Marc, Zhou, Yufeng, Neufeld, Esra, Baumgartner, Christian, Payne, Davnah, Kyriakou, Adamos, Kuster, Niels, Xiao, Xu, McLeod, Helen, Dillon, Christopher, Payne, Allison, Khokhova, Vera A., Sinilshchikov, Ilya, Andriyakhina, Yulia, Rybyanets, Andrey, Shvetsova, Natalia, Berkovich, Alex, Shvetsov, Igor, Shaw, Caroline J., Civale, John, Giussani, Dino, Lees, Christoph, Ozenne, Valery, Toupin, Solenn, Salgaonkar, Vasant, Kaye, Elena, Monette, Sebastien, Maybody, Majid, Srimathveeravalli, Govindarajan, Solomon, Stephen, Gulati, Amitabh, Bezzi, Mario, Jenne, Jürgen W., Lango, Thomas, Müller, Michael, Sat, Giora, Tanner, Christine, Zangos, Stephan, Günther, Matthias, Dinh, Au Hoang, Niaf, Emilie, Bratan, Flavie, Guillen, Nicolas, Souchon, Rémi, Lartizien, Carole, Crouzet, Sebastien, Rouviere, Olivier, Han, Yang, Payen, Thomas, Palermo, Carmine, Sastra, Steve, Olive, Kenneth, van Breugel, Johanna M., van den Bosch, Maurice A., Fellah, Benjamin, Le Bihan, Denis, Hernandez-Garcia, Luis, Cain, Charles A., Lyka, Erasmia, Elbes, Delphine, Li, Chunhui, Tamano, Satoshi, Jimbo, Hayato, Yoshizawa, Shin, Fujiwara, Keisuke, Itani, Kazunori, Umemura, Shin-ichiro, Stoianovici, Dan, Zaini, Zulfadhli, Takagi, Ryo, Zong, Shenyan, Watkins, Ron, Pascal-Tenorio, Aurea, Jones, Peter, Butts-Pauly, Kim, Bouley, Donna, Chen, Yazhu, Lin, Chung-Yin, Hsieh, Han-Yi, Wei, Kuo-Chen, Garnier, Camille, Renault, Gilles, Seifabadi, Reza, Wilson, Emmanuel, Eranki, Avinash, Kim, Peter, Lübke, Dennis, Huber, Peter, Georgii, Joachim, Dresky, Caroline V., Haller, Julian, Yarmolenko, Pavel, Sharma, Karun, Celik, Haydar, Li, Guofeng, Qiu, Weibao, Zheng, Hairong, Tsai, Meng-Yen, Chu, Po-Chun, Webb, Taylor, Vyas, Urvi, Walker, Matthew, Zhong, Jidan, Waspe, Adam C., Hodaie, Mojgan, Yang, Feng-Yi, Huang, Sin-Luo, Zur, Yuval, Assif, Benny, Aurup, Christian, Kamimura, Hermes, Carneiro, Antonio A., Rothlübbers, Sven, Schwaab, Julia, Houston, Graeme, Azhari, Haim, Weiss, Noam, Sosna, Jacob, Goldberg, S. Nahum, Barrere, Victor, Jang, Kee W., Lewis, Bobbi, Wang, Xiaotong, Suomi, Visa, Edwards, David, Larrabee, Zahary, Hananel, Arik, Rafaely, Boaz, Debbiny, Rasha Elaimy, Dekel, Carmel Zeltser, Assa, Michael, Menikou, George, Mouratidis, Petros, Pineda-Pardo, José A., de Pedro, Marta Del Álamo, Martinez, Raul, Hernandez, Frida, Casas, Silvia, Oliver, Carlos, Pastor, Patricia, Vela, Lidia, Obeso, Jose, Greillier, Paul, Zorgani, Ali, Catheline, Stefan, Solovov, Vyacheslav, Vozdvizhenskiy, Michael O., Orlov, Andrew E., Wu, Chueh-Hung, Sun, Ming-Kuan, Shih, Tiffany T., Chen, Wen-Shiang, Prieur, Fabrice, Pillon, Arnaud, Cartron, Valerie, Cebe, Patrick, Chansard, Nathalie, Lafond, Maxime, Seya, Pauline Muleki, Bera, Jean-Christophe, Boissenot, Tanguy, Fattal, Elias, Bordat, Alexandre, Chacun, Helene, Guetin, Claire, Tsapis, Nicolas, Maruyama, Kazuo, Unga, Johan, Suzuki, Ryo, Fant, Cécile, Rogez, Bernadette, Afadzi, Mercy, Myhre, Ola Finneng, Vea, Siri, Bjørkøy, Astrid, Yemane, Petros Tesfamichael, van Wamel, Annemieke, Berg, Sigrid, Hansen, Rune, Angelsen, Bjørn, and Davies, Catharina

Subjects
Meeting Abstracts
Published
2017

13. 5th International Symposium on Focused Ultrasound

Author

Abounader, Roger, Abraham, Christopher, Adema, Gosse, Agrawal, Punit, Airan, Raag, Aleman, Dionne, Alexander, Phillip, Alkins, Ryan, Alnazeer, Moez, Altman, Michael, Aly, Amirah, Amaral, Joao G., Amrahli, Maral, Amraoui, Sana, Andarawewa, Kumari, Andriyakhina, Yulia, Angstadt, Mary, Ankou, Bénédicte, Arias, Ana C., Arvanitis, Costas, Asadnia, Kiana, Aubert, Isabelle, Aubry, Jean-Francois, Aurup, Christian, Bader, Kenneth, Badr, Lena, Baek, Hongchae, Barbato, Gaetano, Beccaria, Kevin, Bellorofonte, Carlo, Benson, Lee, Bernus, Olivier, Berriet, Rémi, Bertolina, Jim, Beskin, Viktoriya, Bessière, Francis, Bethune, Allison, Bezzi, Mario, Bond, Aaron, Bonomo, Guido, Borowsky, Alexander, Borys, Nicolas, Böttcher, Joachim, Bouley, Donna, Bour, Pierre, Bourekas, Eric, Brenin, David, Brokman, Omer, Brosh, Inbar, Buckner, Andrew, Bullock, Timothy, Cafarelli, Andrea, Cahill, Jessica, Camarena, Francisco, Camelo-Piragua, Sandra, Campbell, Benjamin, Campbell, Fiona, Cannata, Jon, Canney, Michael, Carlson, Roy, Carneiro, Antonio, Carpentier, Alexandre, Catheline, Stefan, Cavin, Ian, Cesana, Claudio, Chabok, Hamid R., Chamanara, Marzieh, Chang, Jin H., Chang, Won S., Changizi, Barbara, Chapelon, Jean Y., Chaplin, Vandiver, Chapman, Martin, Chaudhary, Neeraj, Chaussy, Christian, Chen, Cherry, Chen, Johnny, Chen, Wohsing, Chen, Xiaoming, Chevalier, Philippe, Chiou, George, Chisholm, Alexander, Christofferson, Ivy, Chung, Hyun H., Ciuti, Gastone, Clement, Gregory, Cooper, Mark, Corea, Joseph, Corso, Cristiano, Cosman, Josh, Coughlin, Dezba, Crake, Calum, Cunitz, Bryan, Curiel, Laura, Curley, Colleen T., Czarnota, Gregory, Dababou, Susan, Dallapiazza, Robert, de Bever, Joshua, de Jager, Bram, de Ruiter, Joost, de Senneville, Baudouin D., Deckers, Roel, Delattre, Jean-Yves, den Brok, Martijn, Dhanaliwala, Ali, Diodato, Alessandro, Dixon, Adam, Donner, Elizabeth, Downs, Matthew, Du, Zhongmin, Dubois, Rémi, Dupre, Aurelien, Eikelenboom, Dylan, Elias, W. J., Ellens, Nicholas, Endre, Ruby, Eran, Ayelet, Erasmus, Hans-Peter, Everstine, Ashli, Farahani, Keyvan, Farrer, Alexis, Farry, Justin, Federau, Christian, Feng, Xue, Ferrer, Cyril, Ferrera, Vincent, Fishman, Paul, Foley, Jessica, Frenkel, Victor, Fütterer, Jurgen, Gach, H. M., Gandhi, Dheeraj, Gertner, Michael, Goldsher, Dorit, Gorgone, Alessandro, Greillier, Paul, Griesenauer, Rebekah, Grissom, William, Grondin, Julien, Guha, Chandan, Gulati, Amitabh, Gullapalli, Rao, Guo, Sijia, Gupta, Samit, Gurm, Hitinder, Gwinn, Ryder, Hadley, Rock, Haïssaguerre, Michel, Hammoud, Dima, Hananel, Arik, Hargrove, Amelia, Hatch, Robert, Haworth, Kevin, Hazan, Eilon, He, Ye, Heemels, Maurice, Heerschap, Arend, Hilas, Elaine, Hoang-Xuan, Khe, Hocini, Mélèze, Hodaie, Mojgan, Hofmann, Denis, Holland, Christy, Hoogenboom, Martijn, Hopyan, Sevan, Hossack, John, Houdouin, Alexandre, Hsu, Po-Hung, Hu, Jim, Hurwitz, Mark, Huss, Diane, Hwang, Chang-il, Hwang, Joo H., Idbaih, Ahmed, Ikeuchi, Masahiko, Ingham, Elizabeth, Ives, Kimberly, Izumi, Masashi, Jackson-Lewis, Vernice, Janát-Amsbury, Margit, Jang, Kee W., Jedruszczuk, Kathleen, Jiménez-Gambín, Sergio, Jiménez, Noé, Johnson, Sara, Jonathan, Sumeeth, Joy, Joyce, Jung, Hyun H., Jung, Na Y., Kahn, Itamar, Kamimura, Hermes, Kamrava, Seyed K., Kang, Jeeun, Kang, Kook J., Kang, Soo Y., Kao, Yi-tzu, Katti, Prateek, Kawasaki, Motohiro, Kaye, Elena, Keupp, Jochen, Kim, AeRang, Kim, Harry, Kim, Hyun-Chul, Kim, Hyuncheol, Kim, Hyungmin, Kim, Min S., Kim, Namho, Kiyasu, Katsuhito, Kneepkens, Esther, Knopp, Michael, Kobus, Thiele, Koral, Korgun, Kreider, Wayne, Krishna, Vibhor, Krug, Roland, Krupa, Steve, Kuo, Chia-Chun, Kwiecinski, Wojciech, Lacoste, Romain, Lam, Heather, Lamberti-Pasculli, Maria, Lang, Brian, Larner, James, Larrabee, Zachary, Leach, J. K., LeBlang, Suzanne, Leclercq, Delphine, Lee, Hak J., Lee, Jong-Hwan, Lehericy, Stéphane, Leighton, Wan, Leung, Steven, Lewis, Bobbi, Lewis, Matthew, Li, Dawei, Linn, Sabine, Lipsman, Nir, Liu, Hao-Li, Liu, Jingfei, Lopes, M. B., Lotz, Jeff, Lu, Xin, Lundt, Jonathan, Luo, Xi, Lustgarten, Lior, Lustig, Micheal, Macoskey, Jonathan, Madore, Bruno, Maev, Roman, Magat, Julie, Maimbourg, Guillaume, Maimon, Noam, Mainprize, Todd, Malayer, Jerry, Maples, Danny, Marquet, Fabrice, Marrocchio, Cristina, Marx, Mike, Mastorakos, Panagiotis, Mauri, Giovanni, McLean, Hailey, McMichael, John, Mead, Brian P., Melodelima, David, Melot-Dusseau, Sandrine, Menciassi, Arianna, Merrill, Robb, Meyer, Joshua, Midiri, Massimo, Miga, Michael, Migliore, Ilaria G., Miller, Eric, Minalga, Emilee, Moon, Hyungwon, Moore, David, Mourad, Pierre, Mouratidis, Petros, Mueller, Michael, Mugler, John, Muller, Sébastien, Namba, Hirofumi, Naor, Omer, Nassar, Maria, Nazai, Navid, Negron, Karina, Negussie, Ayele, Nguyen, Thai-Son, Nicolay, Klaas, Nikolaeva, Anastasia V., Oetgen, Matthew, Olive, Kenneth, Olumolade, Oluyemi, Orsi, Franco, Owens, Gabe, Ozilgen, Arda, Padegimas, Linas, Palermo, Carmine, Pan, Chia-Hsin, Pandey, Aditya, Papadakis, Georgios, Park, Chang K., Park, Sang M., Parker, Jonathon, Parvizi, Mohammad H., Pascal-Tenorio, Aurea, Patel, Janish, Patz, Sam, Payen, Thomas, Perich, Eloi, Pernot, Mathieu, Perol, David, Perry, James, Pillarisetty, Venu, Pioche, Mathieu, Pizzuto, Matthew, Plaksin, Michael, Plata, Juan, Price, Karl, Prince, Jessica, Przedborski, Serge, Quinones-Hinojosa, Alfredo, Ramachandran, Akhilesh, Ranjan, Ashish, Ravikumar, Vinod, Reichenbach, Juergen, Repasky, Elizabeth, Rezai, Ali, Ritter, Philippe, Rivoire, Michel, Rochman, Carrie, Rosenberg, Jarrett, Rosnitskiy, Pavel B., Ruiz, Antonio, Sahgal, Arjun, Samiotaki, Gesthimani, Sanghvi, Narendra, Santin, Mathieu D., Santos, Domiciano, Sasaki, Noboru, Sastra, Steve, Schade, George, Schall, Jeffrey, Schlesinger, Ilana, Schmitt, Paul, Schwaab, Julia, Scionti, Stephen, Scipione, Roberto, Scoarughi, Gian L., Scott, Serena, Sebeke, Lukas, Seifabadi, Reza, Seo, Jai, Sesenoglu-Laird, Ozge, Shah, Binit, Shahriari, Kian, Shaikh, Sumbul, Shea, Jill, Shi, Jiaqi, Shim, Jenny, Shinkov, Alexander, Shuman, Jillian, Silvestrini, Matthew, Sim, Changbeom, Sin, Vivian, Sinai, Alon, Singh, Manoj, Sinilshchikov, Ilya, Skalina, Karin, Slingluff, Craig, So, Po-Wah, Solomon, Stephen, Son, Keon H., Sperling, Scott, Stein, Ruben, Stein, Sherman, Stevens, Aaron, Stimec, Jennifer, Storm, Gert, Straube, William, Suelmann, Britt, Sutton, Jonathan, Svedin, Bryant, Takemasa, Ryuichi, Takiguchi, Mitsuyoshi, Tam, Emily, Tan, Jeremy, Tang, Xinyan, Tanter, Mickael, Tebebi, Pamela, Tehrani, Seruz, Temple, Michael, Teofilovic, Dejan, ter Haar, Gail, Terzi, Marina E., Thueroff, Stefan, Timbie, Kelsie, Tognarelli, Selene, Tretbar, Steffen, Trudeau, Maureen, Tsai, Yi-Chieh, Tsysar, Sergey A., Tucci, Samantha, Tuveson, David, Ushida, Takahiro, Vaessen, Paul, Vaillant, Fanny, Van Arsdell, Glen, van Breugel, Johanna, Van der Jeugd, Anneke, Van der Wall, Elsken, van Diest, Paul, van Stralen, Marijn, Varano, Gianluca, Velat, Manuela, Vidal-Jove, Joan, Vigna, Paolo D., Vignot, Alexandre, Vincenot, Jeremy, Vykhodtseva, Natalia, Wang, Bin, Wang, Han, Wang, Kevin, Wang, Qi, Wang, Qingguo, Wang, Shengping, Wang, Yak-Nam, Wang, Zhaorui, Wardlow, Rachel, Warren, Amy, Waszczak, Barbara, Watson, Katherine, Webb, Taylor, Wei-Bin, Shen, Wei, Kuo-Chen, Weiss, Steffen, Weissler, Yoni, Werner, Beat, Wesseling, Pieter, Williams, Noelle, Wilson, Emmanuel, Wintermark, Max, Witkamp, Arjen, Wong, Carlos, Wu, Jing-Fu, Wydra, Adrian, Xu, Alexis, Xu, Doudou, Xu, Su, Yang, Georgiana, Yang, Nai-Yi, Yao, Chen, Yarowsky, Paul, Ye, Patrick P., Yuldashev, Petr, Zaaroor, Menashe, Zachiu, Cornel, Zahos, Peter, Zangos, Stephan, Zhang, Dandan, Zhang, Hua, Zhang, Jimin, Zhang, Junhai, Zhang, Xi, Zhao, Li, Zhong, Pei, Zhuo, Jiachen, Zidowitz, Stephan, Zinke, Wolf, Zorgani, Ali, and Aerospace and Ocean Engineering

Subjects
GeneralLiterature_REFERENCE(e.g.,dictionaries,encyclopedias,glossaries)
Abstract

Published version

Published
2016

16. 5th International Symposium on Focused Ultrasound

Author

Zaaroor, Menashe, primary, Sinai, Alon, additional, Goldsher, Dorit, additional, Eran, Ayelet, additional, Nassar, Maria, additional, Schlesinger, Ilana, additional, Parker, Jonathon, additional, Ravikumar, Vinod, additional, Ghanouni, Pejman, additional, Stein, Sherman, additional, Halpern, Casey, additional, Krishna, Vibhor, additional, Hargrove, Amelia, additional, Agrawal, Punit, additional, Changizi, Barbara, additional, Bourekas, Eric, additional, Knopp, Michael, additional, Rezai, Ali, additional, Mead, Brian, additional, Kim, Namho, additional, Mastorakos, Panagiotis, additional, Suk, Jung Soo, additional, Miller, Wilson, additional, Klibanov, Alexander, additional, Hanes, Justin, additional, Price, Richard, additional, Wang, Shutao, additional, Olumolade, Oluyemi, additional, Kugelman, Tara, additional, Jackson-Lewis, Vernice, additional, Karakatsani, Maria Eleni, additional, Han, Yang, additional, Przedborski, Serge, additional, Konofagou, Elisa, additional, Hynynen, Kullervo, additional, Aubert, Isabelle, additional, Leinenga, Gerhard, additional, Nisbet, Rebecca, additional, Hatch, Robert, additional, Van der Jeugd, Anneke, additional, Evans, Harrison, additional, Götz, Jürgen, additional, Van der Jeugd, Ann, additional, Fishman, Paul, additional, Yarowsky, Paul, additional, Frenkel, Victor, additional, Wei-Bin, Shen, additional, Nguyen, Ben, additional, Sanchez, Carlos Sierra, additional, Acosta, Camilo, additional, Chen, Cherry, additional, Wu, Shih-Ying, additional, Aryal, Muna, additional, Papademetriou, Iason T., additional, Zhang, Yong-Zhi, additional, Power, Chanikarn, additional, McDannold, Nathan, additional, Porter, Tyrone, additional, Kovacs, Zsofia, additional, Kim, Saejeong, additional, Jikaria, Neekita, additional, Qureshi, Farhan, additional, Bresler, Michele, additional, Frank, Joseph, additional, Odéen, Henrik, additional, Chiou, George, additional, Snell, John, additional, Todd, Nick, additional, Madore, Bruno, additional, Parker, Dennis, additional, Pauly, Kim Butts, additional, Marx, Mike, additional, Jonathan, Sumeeth, additional, Grissom, William, additional, Arvanitis, Costas, additional, Clement, Gregory, additional, de Bever, Joshua, additional, Payne, Allison, additional, Christensen, Douglas, additional, Maimbourg, Guillaume, additional, Santin, Mathieu David, additional, Houdouin, Alexandre, additional, Lehericy, Stéphane, additional, Tanter, Mickael, additional, Aubry, Jean Francois, additional, Federau, Christian, additional, Werner, Beat, additional, Paeng, Dong-Guk, additional, Xu, Zhiyuan, additional, Quigg, Anders, additional, Eames, Matt, additional, Jin, Changzhu, additional, Everstine, Ashli, additional, Sheehan, Jason, additional, Lopes, M. Beatriz, additional, Kassell, Neal, additional, Drake, James, additional, Price, Karl, additional, Lustgarten, Lior, additional, Sin, Vivian, additional, Mougenot, Charles, additional, Donner, Elizabeth, additional, Tam, Emily, additional, Hodaie, Mojgan, additional, Waspe, Adam, additional, Looi, Thomas, additional, Pichardo, Samuel, additional, Lee, Wonhye, additional, Chung, Yong An, additional, Jung, Yujin, additional, Song, In-Uk, additional, Yoo, Seung-Schik, additional, Kim, Hyun-Chul, additional, Lee, Jong-Hwan, additional, Caskey, Charles, additional, Zinke, Wolf, additional, Cosman, Josh, additional, Shuman, Jillian, additional, Schall, Jeffrey, additional, Aurup, Christian, additional, Chen, Hong, additional, Kamimura, Hermes, additional, Carneiro, Antonio, additional, Sun, Tao, additional, Nazai, Navid, additional, Patz, Sam, additional, Livingstone, Margaret, additional, Mainprize, Todd, additional, Huang, Yuexi, additional, Alkins, Ryan, additional, Chapman, Martin, additional, Perry, James, additional, Lipsman, Nir, additional, Bethune, Allison, additional, Sahgal, Arjun, additional, Trudeau, Maureen, additional, Liu, Hao-Li, additional, Hsu, Po-Hung, additional, Wei, Kuo-Chen, additional, Sutton, Jonathan, additional, Alexander, Phillip, additional, Miller, Eric, additional, Kobus, Thiele, additional, Carpentier, Alexandre, additional, Canney, Michael, additional, Vignot, Alexandre, additional, Beccaria, Kevin, additional, Leclercq, Delphine, additional, Lafon, Cyril, additional, Chapelon, Jean Yves, additional, Hoang-Xuan, Khe, additional, Delattre, Jean-Yves, additional, Idbaih, Ahmed, additional, Moore, David, additional, Xu, Alexis, additional, Schmitt, Paul, additional, Foley, Jessica, additional, Sukovich, Jonathan, additional, Cain, Charles, additional, Pandey, Aditya, additional, Chaudhary, Neeraj, additional, Camelo-Piragua, Sandra, additional, Allen, Steven, additional, Cannata, Jon, additional, Teofilovic, Dejan, additional, Bertolina, Jim, additional, Hall, Timothy, additional, Xu, Zhen, additional, Grondin, Julien, additional, Ferrera, Vincent, additional, ter Haar, Gail, additional, Mouratidis, Petros, additional, Repasky, Elizabeth, additional, Timbie, Kelsie, additional, Badr, Lena, additional, Campbell, Benjamin, additional, McMichael, John, additional, Buckner, Andrew, additional, Prince, Jessica, additional, Stevens, Aaron, additional, Bullock, Timothy, additional, Skalina, Karin, additional, Guha, Chandan, additional, Orsi, Franco, additional, Bonomo, Guido, additional, Vigna, Paolo Della, additional, Mauri, Giovanni, additional, Varano, Gianluca, additional, Schade, George, additional, Wang, Yak-Nam, additional, Pillarisetty, Venu, additional, Hwang, Joo Ha, additional, Khokhlova, Vera, additional, Bailey, Michael, additional, Khokhlova, Tatiana, additional, Sinilshchikov, Ilya, additional, Yuldashev, Petr, additional, Andriyakhina, Yulia, additional, Kreider, Wayne, additional, Maxwell, Adam, additional, Sapozhnikov, Oleg, additional, Partanen, Ari, additional, Lundt, Jonathan, additional, Preusser, Tobias, additional, Haase, Sabrina, additional, Bezzi, Mario, additional, Jenne, Jürgen, additional, Langø, Thomas, additional, Midiri, Massimo, additional, Mueller, Michael, additional, Sat, Giora, additional, Tanner, Christine, additional, Zangos, Stephan, additional, Guenther, Matthias, additional, Melzer, Andreas, additional, Menciassi, Arianna, additional, Tognarelli, Selene, additional, Cafarelli, Andrea, additional, Diodato, Alessandro, additional, Ciuti, Gastone, additional, Rothluebbers, Sven, additional, Schwaab, Julia, additional, Strehlow, Jan, additional, Mihcin, Senay, additional, Tretbar, Steffen, additional, Payen, Thomas, additional, Palermo, Carmine, additional, Sastra, Steve, additional, Olive, Kenneth, additional, Adams, Matthew, additional, Salgaonkar, Vasant, additional, Scott, Serena, additional, Sommer, Graham, additional, Diederich, Chris, additional, Vidal-Jove, Joan, additional, Perich, Eloi, additional, Ruiz, Antonio, additional, Velat, Manuela, additional, Melodelima, David, additional, Dupre, Aurelien, additional, Vincenot, Jeremy, additional, Yao, Chen, additional, Perol, David, additional, Rivoire, Michel, additional, Tucci, Samantha, additional, Mahakian, Lisa, additional, Fite, Brett, additional, Ingham, Elizabeth, additional, Tam, Sarah, additional, Hwang, Chang-il, additional, Tuveson, David, additional, Ferrara, Katherine, additional, Scionti, Stephen, additional, Chen, Lili, additional, Cvetkovic, Dusica, additional, Chen, Xiaoming, additional, Gupta, Roohi, additional, Wang, Bin, additional, Ma, Charlie, additional, Bader, Kenneth, additional, Haworth, Kevin, additional, Holland, Christy, additional, Sanghvi, Narendra, additional, Carlson, Roy, additional, Chen, Wohsing, additional, Chaussy, Christian, additional, Thueroff, Stefan, additional, Cesana, Claudio, additional, Bellorofonte, Carlo, additional, Wang, Qingguo, additional, Wang, Han, additional, Wang, Shengping, additional, Zhang, Junhai, additional, Bazzocchi, Alberto, additional, Napoli, Alessandro, additional, Staruch, Robert, additional, Bing, Chenchen, additional, Shaikh, Sumbul, additional, Nofiele, Joris, additional, Szczepanski, Debra, additional, Staruch, Michelle Wodzak, additional, Williams, Noelle, additional, Laetsch, Theodore, additional, Chopra, Rajiv, additional, Rosenberg, Jarrett, additional, Bitton, Rachelle, additional, LeBlang, Suzanne, additional, Meyer, Joshua, additional, Hurwitz, Mark, additional, Yarmolenko, Pavel, additional, Celik, Haydar, additional, Eranki, Avinash, additional, Beskin, Viktoriya, additional, Santos, Domiciano, additional, Patel, Janish, additional, Oetgen, Matthew, additional, Kim, AeRang, additional, Kim, Peter, additional, Sharma, Karun, additional, Chisholm, Alexander, additional, Aleman, Dionne, additional, Scipione, Roberto, additional, Temple, Michael, additional, Amaral, Joao Guilherme, additional, Endre, Ruby, additional, Lamberti-Pasculli, Maria, additional, de Ruiter, Joost, additional, Campbell, Fiona, additional, Stimec, Jennifer, additional, Gupta, Samit, additional, Singh, Manoj, additional, Hopyan, Sevan, additional, Czarnota, Gregory, additional, Brenin, David, additional, Rochman, Carrie, additional, Kovatcheva, Roussanka, additional, Vlahov, Jordan, additional, Zaletel, Katja, additional, Stoinov, Julian, additional, Bucknor, Matthew, additional, Rieke, Viola, additional, Shim, Jenny, additional, Koral, Korgun, additional, Lang, Brian, additional, Wong, Carlos, additional, Lam, Heather, additional, Shinkov, Alexander, additional, Hu, Jim, additional, Zhang, Xi, additional, Macoskey, Jonathan, additional, Ives, Kimberly, additional, Owens, Gabe, additional, Gurm, Hitinder, additional, Shi, Jiaqi, additional, Pizzuto, Matthew, additional, Dillon, Christopher, additional, Christofferson, Ivy, additional, Hilas, Elaine, additional, Shea, Jill, additional, Greillier, Paul, additional, Ankou, Bénédicte, additional, Bessière, Francis, additional, Zorgani, Ali, additional, Pioche, Mathieu, additional, Kwiecinski, Wojciech, additional, Magat, Julie, additional, Melot-Dusseau, Sandrine, additional, Lacoste, Romain, additional, Quesson, Bruno, additional, Pernot, Mathieu, additional, Catheline, Stefan, additional, Chevalier, Philippe, additional, Marquet, Fabrice, additional, Bour, Pierre, additional, Vaillant, Fanny, additional, Amraoui, Sana, additional, Dubois, Rémi, additional, Ritter, Philippe, additional, Haïssaguerre, Michel, additional, Hocini, Mélèze, additional, Bernus, Olivier, additional, Tebebi, Pamela, additional, Burks, Scott, additional, Milo, Blerta, additional, Gertner, Michael, additional, Zhang, Jimin, additional, Wong, Andrew, additional, Liu, Yu, additional, Kheirolomoom, Azadeh, additional, Seo, Jai, additional, Watson, Katherine, additional, Zhang, Hua, additional, Foiret, Josquin, additional, Borowsky, Alexander, additional, Xu, Doudou, additional, Thanou, Maya, additional, Centelles, Miguell, additional, Wright, Mike, additional, Amrahli, Maral, additional, So, Po-Wah, additional, Gedroyc, Wladyslaw, additional, Kneepkens, Esther, additional, Heijman, Edwin, additional, Keupp, Jochen, additional, Weiss, Steffen, additional, Nicolay, Klaas, additional, Grüll, Holger, additional, Nagle, Matthew, additional, Nikolaeva, Anastasia V., additional, Terzi, Marina E., additional, Tsysar, Sergey A., additional, Cunitz, Bryan, additional, Mourad, Pierre, additional, Downs, Matthew, additional, Yang, Georgiana, additional, Wang, Qi, additional, Chen, Johnny, additional, Farry, Justin, additional, Dixon, Adam, additional, Du, Zhongmin, additional, Dhanaliwala, Ali, additional, Hossack, John, additional, Ranjan, Ashish, additional, Maples, Danny, additional, Wardlow, Rachel, additional, Malayer, Jerry, additional, Ramachandran, Akhilesh, additional, Namba, Hirofumi, additional, Kawasaki, Motohiro, additional, Izumi, Masashi, additional, Kiyasu, Katsuhito, additional, Takemasa, Ryuichi, additional, Ikeuchi, Masahiko, additional, Ushida, Takahiro, additional, Crake, Calum, additional, Kothapalli, Satya V. V. N., additional, Leighton, Wan, additional, Wang, Zhaorui, additional, Gach, H. Michael, additional, Straube, William, additional, Altman, Michael, additional, Kim, Young-sun, additional, Lim, Hyo Keun, additional, Rhim, Hyunchul, additional, van Breugel, Johanna, additional, Braat, Manon, additional, Moonen, Chrit, additional, van den Bosch, Maurice, additional, Ries, Mario, additional, Marrocchio, Cristina, additional, Dababou, Susan, additional, Lee, Jae Young, additional, Chung, Hyun Hoon, additional, Kang, Soo Yeon, additional, Kang, Kook Jin, additional, Son, Keon Ho, additional, Zhang, Dandan, additional, Plata, Juan, additional, Jones, Peter, additional, Pascal-Tenorio, Aurea, additional, Bouley, Donna, additional, Bond, Aaron, additional, Dallapiazza, Robert, additional, Huss, Diane, additional, Warren, Amy, additional, Sperling, Scott, additional, Gwinn, Ryder, additional, Shah, Binit, additional, Elias, W. Jeff, additional, Curley, Colleen, additional, Zhang, Ying, additional, Negron, Karina, additional, Abounader, Roger, additional, Samiotaki, Gesthimani, additional, Tu, Tsang-Wei, additional, Papadakis, Georgios, additional, Hammoud, Dima, additional, Silvestrini, Matthew, additional, Wolfram, Frank, additional, Güllmar, Daniel, additional, Reichenbach, Juergen, additional, Hofmann, Denis, additional, Böttcher, Joachim, additional, Schubert, Harald, additional, Lesser, Thomas G., additional, Almquist, Scott, additional, Camarena, Francisco, additional, Jiménez-Gambín, Sergio, additional, Jiménez, Noé, additional, Chang, Jin Woo, additional, Chaplin, Vandiver, additional, Griesenauer, Rebekah, additional, Miga, Michael, additional, Ellens, Nicholas, additional, Airan, Raag, additional, Quinones-Hinojosa, Alfredo, additional, Farahani, Keyvan, additional, Feng, Xue, additional, Fielden, Samuel, additional, Zhao, Li, additional, Wintermark, Max, additional, Meyer, Craig, additional, Guo, Sijia, additional, Lu, Xin, additional, Zhuo, Jiachen, additional, Xu, Su, additional, Gullapalli, Rao, additional, Gandhi, Dheeraj, additional, Brokman, Omer, additional, Baek, Hongchae, additional, Kim, Hyungmin, additional, Leung, Steven, additional, Webb, Taylor, additional, Vykhodtseva, Natalia, additional, Nguyen, Thai-Son, additional, Park, Chang Kyu, additional, Park, Sang Man, additional, Jung, Na Young, additional, Kim, Min Soo, additional, Chang, Won Seok, additional, Jung, Hyun Ho, additional, Plaksin, Michael, additional, Weissler, Yoni, additional, Shoham, Shy, additional, Kimmel, Eitan, additional, Rosnitskiy, Pavel B., additional, Krupa, Steve, additional, Hazan, Eilon, additional, Naor, Omer, additional, Levy, Yoav, additional, Maimon, Noam, additional, Brosh, Inbar, additional, Kahn, Itamar, additional, Cahill, Jessica, additional, Colas, Elodie Constanciel, additional, Wydra, Adrian, additional, Maev, Roman, additional, Aly, Amirah, additional, Sesenoglu-Laird, Ozge, additional, Padegimas, Linas, additional, Cooper, Mark, additional, Waszczak, Barbara, additional, Tehrani, Seruz, additional, Slingluff, Craig, additional, Larner, James, additional, Andarawewa, Kumari, additional, Ozhinsky, Eugene, additional, Shah, Rutwik, additional, Krug, Roland, additional, Deckers, Roel, additional, Linn, Sabine, additional, Suelmann, Britt, additional, Witkamp, Arjen, additional, Vaessen, Paul, additional, van Diest, Paul, additional, Bartels, Lambertus W., additional, Bos, Clemens, additional, Borys, Nicolas, additional, Storm, Gert, additional, Van der Wall, Elsken, additional, Farr, Navid, additional, Alnazeer, Moez, additional, Katti, Prateek, additional, Wood, Bradford, additional, Farrer, Alexis, additional, Ferrer, Cyril, additional, de Senneville, Baudouin Denis, additional, van Stralen, Marijn, additional, Liu, Jingfei, additional, Leach, J. Kent, additional, Zidowitz, Stephan, additional, Lee, Hsin-Lun, additional, Hsu, Fang-Chi, additional, Kuo, Chia-Chun, additional, Jeng, Shiu-Chen, additional, Chen, Tung-Ho, additional, Yang, Nai-Yi, additional, Chiou, Jeng-Fong, additional, Kao, Yi-tzu, additional, Pan, Chia-Hsin, additional, Wu, Jing-Fu, additional, Tsai, Yi-Chieh, additional, Johnson, Sara, additional, Li, Dawei, additional, He, Ye, additional, Karakitsios, Ioannis, additional, Schwenke, Michael, additional, Demedts, Daniel, additional, Xiao, Xu, additional, Cavin, Ian, additional, Minalga, Emilee, additional, Merrill, Robb, additional, Hadley, Rock, additional, Ramaekers, Pascal, additional, de Greef, Martijn, additional, Shahriari, Kian, additional, Parvizi, Mohammad Hossein, additional, Asadnia, Kiana, additional, Chamanara, Marzieh, additional, Kamrava, Seyed Kamran, additional, Chabok, Hamid Reza, additional, Stein, Ruben, additional, Muller, Sébastien, additional, Tan, Jeremy, additional, Zachiu, Cornel, additional, Erasmus, Hans-Peter, additional, Van Arsdell, Glen, additional, Benson, Lee, additional, Jang, Kee W., additional, Angstadt, Mary, additional, Lewis, Bobbi, additional, McLean, Hailey, additional, Hoogenboom, Martijn, additional, Eikelenboom, Dylan, additional, den Brok, Martijn, additional, Wesseling, Pieter, additional, Heerschap, Arend, additional, Fütterer, Jurgen, additional, Adema, Gosse, additional, Wang, Kevin, additional, Zhong, Pei, additional, Joy, Joyce, additional, McLeod, Helen, additional, Kim, Harry, additional, Lewis, Matthew, additional, Ozilgen, Arda, additional, Zahos, Peter, additional, Coughlin, Dezba, additional, Tang, Xinyan, additional, Lotz, Jeff, additional, Jedruszczuk, Kathleen, additional, Gulati, Amitabh, additional, Solomon, Stephen, additional, Kaye, Elena, additional, Mugler, John, additional, Barbato, Gaetano, additional, Scoarughi, Gian Luca, additional, Corso, Cristiano, additional, Gorgone, Alessandro, additional, Migliore, Ilaria Giuseppina, additional, Larrabee, Zachary, additional, Hananel, Arik, additional, Aubry, Jean-Francois, additional, Negussie, Ayele, additional, Wilson, Emmanuel, additional, Seifabadi, Reza, additional, Moon, Hyungwon, additional, Kang, Jeeun, additional, Sim, Changbeom, additional, Chang, Jin Ho, additional, Kim, Hyuncheol, additional, Lee, Hak Jong, additional, Sasaki, Noboru, additional, Takiguchi, Mitsuyoshi, additional, Sebeke, Lukas, additional, Luo, Xi, additional, de Jager, Bram, additional, Heemels, Maurice, additional, Abraham, Christopher, additional, Curiel, Laura, additional, Berriet, Rémi, additional, Janát-Amsbury, Margit, additional, Corea, Joseph, additional, Ye, Patrick Peiyong, additional, Arias, Ana Clauda, additional, Lustig, Micheal, additional, and Svedin, Bryant, additional

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2016
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25. International Society for Therapeutic Ultrasound Conference 2016: Tel Aviv, Israel. 14-18 March, 2016

Author

Fowlkes, Brian, Ghanouni, Pejman, Sanghvi, Narendra, Coussios, Constantin, Lyon, Paul C., Gray, Michael, Mannaris, Christophoros, Victor, Marie de Saint, Stride, Eleanor, Cleveland, Robin, Carlisle, Robert, Wu, Feng, Middleton, Mark, Gleeson, Fergus, Aubry, Jean-Franҫois, Pauly, Kim Butts, Moonen, Chrit, Vortman, Jacob, Sharabi, Shirley, Daniels, Dianne, Last, David, Guez, David, Levy, Yoav, Volovick, Alexander, Grinfeld, Javier, Rachmilevich, Itay, Amar, Talia, Zibly, Zion, Mardor, Yael, Harnof, Sagi, Plaksin, Michael, Weissler, Yoni, Shoham, Shy, Kimmel, Eitan, Naor, Omer, Farah, Nairouz, Paeng, Dong-Guk, Xu, Zhiyuan, Snell, John, Quigg, Anders H., Eames, Matthew, Jin, Changzhu, Everstine, Ashli C., Sheehan, Jason P., Lopes, Beatriz S., Kassell, Neal, Looi, Thomas, Khokhlova, Vera, Mougenot, Charles, Hynynen, Kullervo, Drake, James, Slayton, Michael, Amodei, Richard C., Compton, Keegan, McNelly, Ashley, Latt, Daniel, Kearney, John, Melodelima, David, Dupre, Aurelien, Chen, Yao, Perol, David, Vincenot, Jeremy, Chapelon, Jean-Yves, Rivoire, Michel, Guo, Wei, Ren, Guoxin, Shen, Guofeng, Neidrauer, Michael, Zubkov, Leonid, Weingarten, Michael S., Margolis, David J., Lewin, Peter A., McDannold, Nathan, Sutton, Jonathan, Vykhodtseva, Natalia, Livingstone, Margaret, Kobus, Thiele, Zhang, Yong-Zhi, Schwartz, Michael, Huang, Yuexi, Lipsman, Nir, Jain, Jennifer, Chapman, Martin, Sankar, Tejas, Lozano, Andres, Yeung, Robert, Damianou, Christakis, Papadopoulos, Nikolaos, Brokman, Omer, Zadicario, Eyal, Brenner, Ori, Castel, David, Wu, Shih-Ying, Grondin, Julien, Zheng, Wenlan, Heidmann, Marc, Karakatsani, Maria Eleni, Sánchez, Carlos J. Sierra, Ferrera, Vincent, Konofagou, Elisa E., Yiannakou, Marinos, Cho, HongSeok, Lee, Hwayoun, Han, Mun, Choi, Jong-Ryul, Lee, Taekwan, Ahn, Sanghyun, Chang, Yongmin, Park, Juyoung, Ellens, Nicholas, Partanen, Ari, Farahani, Keyvan, Airan, Raag, Carpentier, Alexandre, Canney, Michael, Vignot, Alexandre, Lafon, Cyril, Delattre, Jean-yves, Idbaih, Ahmed, Odéen, Henrik, Bolster, Bradley, Jeong, Eun Kee, Parker, Dennis L., Gaur, Pooja, Feng, Xue, Fielden, Samuel, Meyer, Craig, Werner, Beat, Grissom, William, Marx, Michael, Weber, Hans, Taviani, Valentina, Hargreaves, Brian, Tanaka, Jun, Kikuchi, Kentaro, Ishijima, Ayumu, Azuma, Takashi, Minamihata, Kosuke, Yamaguchi, Satoshi, Nagamune, Teruyuki, Sakuma, Ichiro, Takagi, Shu, Santin, Mathieu D., Marsac, Laurent, Maimbourg, Guillaume, Monfort, Morgane, Larrat, Benoit, François, Chantal, Lehéricy, Stéphane, Tanter, Mickael, Samiotaki, Gesthimani, Wang, Shutao, Acosta, Camilo, Feinberg, Eliza R., Kovacs, Zsofia I., Tu, Tsang-Wei, Papadakis, Georgios Z., Reid, William C., Hammoud, Dima A., Frank, Joseph A., Kovacs, Zsofia i., Kim, Saejeong, Jikaria, Neekita, Bresler, Michele, Qureshi, Farhan, Xia, Jingjing, Tsui, Po-Shiang, Liu, Hao-Li, Plata, Juan C., Sveinsson, Bragi, Salgaonkar, Vasant A., Adams, Matthew, Diederich, Chris, Ozhinsky, Eugene, Bucknor, Matthew D., Rieke, Viola, Mikhail, Andrew, Severance, Lauren, Negussie, Ayele H., Wood, Bradford, de Greef, Martijn, Schubert, Gerald, Ries, Mario, Poorman, Megan E., Dockery, Mary, Chaplin, Vandiver, Dudzinski, Stephanie O., Spears, Ryan, Caskey, Charles, Giorgio, Todd, Costa, Marcia M., Papaevangelou, Efthymia, Shah, Anant, Rivens, Ian, Box, Carol, Bamber, Jeff, ter Haar, Gail, Burks, Scott R., Nagle, Matthew, Nguyen, Ben, Milo, Blerta, Le, Nhan M., Song, Shaozhen, Zhou, Kanheng, Nabi, Ghulam, Huang, Zhihong, Ben-Ezra, Shmuel, Rosen, Shani, Mihcin, Senay, Strehlow, Jan, Karakitsios, Ioannis, Le, Nhan, Schwenke, Michael, Demedts, Daniel, Prentice, Paul, Haase, Sabrina, Preusser, Tobias, Melzer, Andreas, Mestas, Jean-Louis, Chettab, Kamel, Gomez, Gustavo Stadthagen, Dumontet, Charles, Werle, Bettina, Marquet, Fabrice, Bour, Pierre, Vaillant, Fanny, Amraoui, Sana, Dubois, Rémi, Ritter, Philippe, Haïssaguerre, Michel, Hocini, Mélèze, Bernus, Olivier, Quesson, Bruno, Livneh, Amit, Adam, Dan, Robin, Justine, Arnal, Bastien, Fink, Mathias, Pernot, Mathieu, Khokhlova, Tatiana D., Schade, George R., Wang, Yak-Nam, Kreider, Wayne, Simon, Julianna, Starr, Frank, Karzova, Maria, Maxwell, Adam, Bailey, Michael R., Lundt, Jonathan E., Allen, Steven P., Sukovich, Jonathan R., Hall, Timothy, Xu, Zhen, May, Philip, Lin, Daniel W., Constans, Charlotte, Deffieux, Thomas, Aubry, Jean-Francois, Park, Eun-Joo, Ahn, Yun Deok, Kang, Soo Yeon, Park, Dong-Hyuk, Lee, Jae Young, Vidal-Jove, J., Perich, E., Ruiz, A., Jaen, A., Eres, N., del Castillo, M. Alvarez, Myers, Rachel, Kwan, James, Coviello, Christian, Rowe, Cliff, Crake, Calum, Finn, Sean, Jackson, Edward, Pouliopoulos, Antonios, Li, Caiqin, Tinguely, Marc, Tang, Meng-Xing, Garbin, Valeria, Choi, James J., Folkes, Lisa, Stratford, Michael, Nwokeoha, Sandra, Li, Tong, Farr, Navid, D’Andrea, Samantha, Gravelle, Kayla, Chen, Hong, Lee, Donghoon, Hwang, Joo Ha, Tardoski, Sophie, Ngo, Jacqueline, Gineyts, Evelyne, Roux, Jean-Pau, Clézardin, Philippe, Conti, Allegra, Magnin, Rémi, Gerstenmayer, Matthieu, Lux, François, Tillement, Olivier, Mériaux, Sébastien, Penna, Stefania Della, Romani, Gian Luca, Dumont, Erik, Sun, Tao, Power, Chanikarn, Miller, Eric, Sapozhnikov, Oleg, Tsysar, Sergey, Yuldashev, Petr V., Svet, Victor, Li, Dongli, Pellegrino, Antonio, Petrinic, Nik, Siviour, Clive, Jerusalem, Antoine, Yuldashev, Peter V., Cunitz, Bryan W., Dunmire, Barbrina, Inserra, Claude, Guedra, Matthieu, Mauger, Cyril, Gilles, Bruno, Solovchuk, Maxim, Sheu, Tony W. H., Thiriet, Marc, Zhou, Yufeng, Neufeld, Esra, Baumgartner, Christian, Payne, Davnah, Kyriakou, Adamos, Kuster, Niels, Xiao, Xu, McLeod, Helen, Dillon, Christopher, Payne, Allison, Khokhova, Vera A., Sinilshchikov, Ilya, Andriyakhina, Yulia, Rybyanets, Andrey, Shvetsova, Natalia, Berkovich, Alex, Shvetsov, Igor, Shaw, Caroline J., Civale, John, Giussani, Dino, Lees, Christoph, Ozenne, Valery, Toupin, Solenn, Salgaonkar, Vasant, Kaye, Elena, Monette, Sebastien, Maybody, Majid, Srimathveeravalli, Govindarajan, Solomon, Stephen, Gulati, Amitabh, Bezzi, Mario, Jenne, Jürgen W., Lango, Thomas, Müller, Michael, Sat, Giora, Tanner, Christine, Zangos, Stephan, Günther, Matthias, Dinh, Au Hoang, Niaf, Emilie, Bratan, Flavie, Guillen, Nicolas, Souchon, Rémi, Lartizien, Carole, Crouzet, Sebastien, Rouviere, Olivier, Han, Yang, Payen, Thomas, Palermo, Carmine, Sastra, Steve, Olive, Kenneth, van Breugel, Johanna M., van den Bosch, Maurice A., Fellah, Benjamin, Le Bihan, Denis, Hernandez-Garcia, Luis, Cain, Charles A., Lyka, Erasmia, Elbes, Delphine, Li, Chunhui, Tamano, Satoshi, Jimbo, Hayato, Yoshizawa, Shin, Fujiwara, Keisuke, Itani, Kazunori, Umemura, Shin-ichiro, Stoianovici, Dan, Zaini, Zulfadhli, Takagi, Ryo, Zong, Shenyan, Watkins, Ron, Pascal-Tenorio, Aurea, Jones, Peter, Butts-Pauly, Kim, Bouley, Donna, Chen, Yazhu, Lin, Chung-Yin, Hsieh, Han-Yi, Wei, Kuo-Chen, Garnier, Camille, Renault, Gilles, Seifabadi, Reza, Wilson, Emmanuel, Eranki, Avinash, Kim, Peter, Lübke, Dennis, Huber, Peter, Georgii, Joachim, Dresky, Caroline V., Haller, Julian, Yarmolenko, Pavel, Sharma, Karun, Celik, Haydar, Li, Guofeng, Qiu, Weibao, Zheng, Hairong, Tsai, Meng-Yen, Chu, Po-Chun, Webb, Taylor, Vyas, Urvi, Walker, Matthew, Zhong, Jidan, Waspe, Adam C., Hodaie, Mojgan, Yang, Feng-Yi, Huang, Sin-Luo, Zur, Yuval, Assif, Benny, Aurup, Christian, Kamimura, Hermes, Carneiro, Antonio A., Rothlübbers, Sven, Schwaab, Julia, Houston, Graeme, Azhari, Haim, Weiss, Noam, Sosna, Jacob, Goldberg, S. Nahum, Barrere, Victor, Jang, Kee W., Lewis, Bobbi, Wang, Xiaotong, Suomi, Visa, Edwards, David, Larrabee, Zahary, Hananel, Arik, Rafaely, Boaz, Debbiny, Rasha Elaimy, Dekel, Carmel Zeltser, Assa, Michael, Menikou, George, Mouratidis, Petros, Pineda-Pardo, José A., de Pedro, Marta Del Álamo, Martinez, Raul, Hernandez, Frida, Casas, Silvia, Oliver, Carlos, Pastor, Patricia, Vela, Lidia, Obeso, Jose, Greillier, Paul, Zorgani, Ali, Catheline, Stefan, Solovov, Vyacheslav, Vozdvizhenskiy, Michael O., Orlov, Andrew E., Wu, Chueh-Hung, Sun, Ming-Kuan, Shih, Tiffany T., Chen, Wen-Shiang, Prieur, Fabrice, Pillon, Arnaud, Cartron, Valerie, Cebe, Patrick, Chansard, Nathalie, Lafond, Maxime, Seya, Pauline Muleki, Bera, Jean-Christophe, Boissenot, Tanguy, Fattal, Elias, Bordat, Alexandre, Chacun, Helene, Guetin, Claire, Tsapis, Nicolas, Maruyama, Kazuo, Unga, Johan, Suzuki, Ryo, Fant, Cécile, Rogez, Bernadette, Afadzi, Mercy, Myhre, Ola Finneng, Vea, Siri, Bjørkøy, Astrid, Yemane, Petros Tesfamichael, van Wamel, Annemieke, Berg, Sigrid, Hansen, Rune, Angelsen, Bjørn, and Davies, Catharina

Published
2017
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26. Differential Role of Apoptosis and Autophagy Associated with Anticancer Effect of Lupulone (Hop -Acid) Derivatives on Prostate Cancer Cells

Author

X.E. Mouratidis, Petros, W. Colston, Kay, Charolidi, Nicoletta, and Pirianov, Grisha

Abstract

Lupulone, a -acid derived from hop extracts has been shown to exhibit cytotoxic activity against cancer cells. In this study we investigated the functional role of different modes of cell death that mediate anticancer effect of lupulone derivatives in prostate cancer cells. ELISA, immunoblotting and siRNA approaches were utilised to study cell death, expression of proteins of interest and their functional activities. We found that the anticancer effect of lupulone derivatives on prostate cancer cells is associated with induction of apoptosis and autophagy as determined by increases of DNA fragmentation and LC3I/ LC3II conversion respectively. Inhibition of apoptosis using a pan-caspase inhibitor resulted in increased levels of autophagy. Following screening of proteins associated with autophagy we found that Atg4 expression was increased in prostate cancer cells after treatment with lupulone. Transfection of cells with siRNA against Atg4 resulted in increased levels of apoptosis in prostate cancer cells. Treatment of prostate cancer cells with lupulone derivatives initiated two modes of cell death: apoptosis as a killing pathway and autophagy as a protection against cell death. Further studies are required to investigate the regulation of Atg4β activity in lupulone derivatives-induced negative crosstalk between apoptosis and autophagy.

Published
2014

27. 5th International Symposium on Focused Ultrasound

Author

Zaaroor, Menashe, Sinai, Alon, Goldsher, Dorit, Eran, Ayelet, Nassar, Maria, Schlesinger, Ilana, Parker, Jonathon, Ravikumar, Vinod, Ghanouni, Pejman, Stein, Sherman, Halpern, Casey, Krishna, Vibhor, Hargrove, Amelia, Agrawal, Punit, Changizi, Barbara, Bourekas, Eric, Knopp, Michael, Rezai, Ali, Mead, Brian, Kim, Namho, Mastorakos, Panagiotis, Suk, Jung Soo, Miller, Wilson, Klibanov, Alexander, Hanes, Justin, Price, Richard, Wang, Shutao, Olumolade, Oluyemi, Kugelman, Tara, Jackson-Lewis, Vernice, Karakatsani, Maria Eleni (Marilena), Han, Yang, Przedborski, Serge, Konofagou, Elisa, Hynynen, Kullervo, Aubert, Isabelle, Leinenga, Gerhard, Nisbet, Rebecca, Hatch, Robert, Van der Jeugd, Anneke, Evans, Harrison, Götz, Jürgen, Van der Jeugd, Ann, Fishman, Paul, Yarowsky, Paul, Frenkel, Victor, Wei-Bin, Shen, Nguyen, Ben, Sanchez, Carlos Sierra, Acosta, Camilo, Chen, Cherry, Wu, Shih-Ying, Aryal, Muna, Papademetriou, Iason T., Zhang, Yong-Zhi, Power, Chanikarn, McDannold, Nathan, Porter, Tyrone, Kovacs, Zsofia, Kim, Saejeong, Jikaria, Neekita, Qureshi, Farhan, Bresler, Michele, Frank, Joseph, Odéen, Henrik, Chiou, George, Snell, John, Todd, Nick, Madore, Bruno, Parker, Dennis, Pauly, Kim Butts, Marx, Mike, Jonathan, Sumeeth, Grissom, William, Arvanitis, Costas, Clement, Gregory, de Bever, Joshua, Payne, Allison, Christensen, Douglas, Maimbourg, Guillaume, Santin, Mathieu David, Houdouin, Alexandre, Lehericy, Stéphane, Tanter, Mickael, Aubry, Jean Francois, Federau, Christian, Werner, Beat, Paeng, Dong-Guk, Xu, Zhiyuan, Quigg, Anders, Eames, Matt, Jin, Changzhu, Everstine, Ashli, Sheehan, Jason, Lopes, M. Beatriz, Kassell, Neal, Drake, James, Price, Karl, Lustgarten, Lior, Sin, Vivian, Mougenot, Charles, Donner, Elizabeth, Tam, Emily, Hodaie, Mojgan, Waspe, Adam, Looi, Thomas, Pichardo, Samuel, Lee, Wonhye, Chung, Yong An, Jung, Yujin, Song, In-Uk, Yoo, Seung-Schik, Kim, Hyun-Chul, Lee, Jong-Hwan, Caskey, Charles, Zinke, Wolf, Cosman, Josh, Shuman, Jillian, Schall, Jeffrey, Aurup, Christian, Chen, Hong, Kamimura, Hermes, Carneiro, Antonio, Sun, Tao, Nazai, Navid, Patz, Sam, Livingstone, Margaret, Mainprize, Todd, Huang, Yuexi, Alkins, Ryan, Chapman, Martin, Perry, James, Lipsman, Nir, Bethune, Allison, Sahgal, Arjun, Trudeau, Maureen, Liu, Hao-Li, Hsu, Po-Hung, Wei, Kuo-Chen, Sutton, Jonathan, Alexander, Phillip, Miller, Eric, Kobus, Thiele, Carpentier, Alexandre, Canney, Michael, Vignot, Alexandre, Beccaria, Kevin, Leclercq, Delphine, Lafon, Cyril, Chapelon, Jean Yves, Hoang-Xuan, Khe, Delattre, Jean-Yves, Idbaih, Ahmed, Moore, David, Xu, Alexis, Schmitt, Paul, Foley, Jessica, Sukovich, Jonathan, Cain, Charles, Pandey, Aditya, Chaudhary, Neeraj, Camelo-Piragua, Sandra, Allen, Steven, Cannata, Jon, Teofilovic, Dejan, Bertolina, Jim, Hall, Timothy, Xu, Zhen, Grondin, Julien, Ferrera, Vincent, ter Haar, Gail, Mouratidis, Petros, Repasky, Elizabeth, Timbie, Kelsie, Badr, Lena, Campbell, Benjamin, McMichael, John, Buckner, Andrew, Prince, Jessica, Stevens, Aaron, Bullock, Timothy, Skalina, Karin, Guha, Chandan, Orsi, Franco, Bonomo, Guido, Vigna, Paolo Della, Mauri, Giovanni, Varano, Gianluca, Schade, George, Wang, Yak-Nam, Pillarisetty, Venu, Hwang, Joo Ha, Khokhlova, Vera, Bailey, Michael, Khokhlova, Tatiana, Sinilshchikov, Ilya, Yuldashev, Petr, Andriyakhina, Yulia, Kreider, Wayne, Maxwell, Adam, Sapozhnikov, Oleg, Partanen, Ari, Lundt, Jonathan, Preusser, Tobias, Haase, Sabrina, Bezzi, Mario, Jenne, Jürgen, Langø, Thomas, Midiri, Massimo, Mueller, Michael, Sat, Giora, Tanner, Christine, Zangos, Stephan, Guenther, Matthias, Melzer, Andreas, Menciassi, Arianna, Tognarelli, Selene, Cafarelli, Andrea, Diodato, Alessandro, Ciuti, Gastone, Rothluebbers, Sven, Schwaab, Julia, Strehlow, Jan, Mihcin, Senay, Tretbar, Steffen, Payen, Thomas, Palermo, Carmine, Sastra, Steve, Olive, Kenneth, Adams, Matthew, Salgaonkar, Vasant, Scott, Serena, Sommer, Graham, Diederich, Chris, Vidal-Jove, Joan, Perich, Eloi, Ruiz, Antonio, Velat, Manuela, Melodelima, David, Dupre, Aurelien, Vincenot, Jeremy, Yao, Chen, Perol, David, Rivoire, Michel, Tucci, Samantha, Mahakian, Lisa, Fite, Brett, Ingham, Elizabeth, Tam, Sarah, Hwang, Chang-il, Tuveson, David, Ferrara, Katherine, Scionti, Stephen, Chen, Lili, Cvetkovic, Dusica, Chen, Xiaoming, Gupta, Roohi, Wang, Bin, Ma, Charlie, Bader, Kenneth, Haworth, Kevin, Holland, Christy, Sanghvi, Narendra, Carlson, Roy, Chen, Wohsing, Chaussy, Christian, Thueroff, Stefan, Cesana, Claudio, Bellorofonte, Carlo, Wang, Qingguo, Wang, Han, Wang, Shengping, Zhang, Junhai, Bazzocchi, Alberto, Napoli, Alessandro, Staruch, Robert, Bing, Chenchen, Shaikh, Sumbul, Nofiele, Joris, Szczepanski, Debra, Staruch, Michelle Wodzak, Williams, Noelle, Laetsch, Theodore, Chopra, Rajiv, Rosenberg, Jarrett, Bitton, Rachelle, LeBlang, Suzanne, Meyer, Joshua, Hurwitz, Mark, Yarmolenko, Pavel, Celik, Haydar, Eranki, Avinash, Beskin, Viktoriya, Santos, Domiciano, Patel, Janish, Oetgen, Matthew, Kim, AeRang, Kim, Peter, Sharma, Karun, Chisholm, Alexander, Aleman, Dionne, Scipione, Roberto, Temple, Michael, Amaral, Joao Guilherme, Endre, Ruby, Lamberti-Pasculli, Maria, de Ruiter, Joost, Campbell, Fiona, Stimec, Jennifer, Gupta, Samit, Singh, Manoj, Hopyan, Sevan, Czarnota, Gregory, Brenin, David, Rochman, Carrie, Kovatcheva, Roussanka, Vlahov, Jordan, Zaletel, Katja, Stoinov, Julian, Bucknor, Matthew, Rieke, Viola, Shim, Jenny, Koral, Korgun, Lang, Brian, Wong, Carlos, Lam, Heather, Shinkov, Alexander, Hu, Jim, Zhang, Xi, Macoskey, Jonathan, Ives, Kimberly, Owens, Gabe, Gurm, Hitinder, Shi, Jiaqi, Pizzuto, Matthew, Dillon, Christopher, Christofferson, Ivy, Hilas, Elaine, Shea, Jill, Greillier, Paul, Ankou, Bénédicte, Bessière, Francis, Zorgani, Ali, Pioche, Mathieu, Kwiecinski, Wojciech, Magat, Julie, Melot-Dusseau, Sandrine, Lacoste, Romain, Quesson, Bruno, Pernot, Mathieu, Catheline, Stefan, Chevalier, Philippe, Marquet, Fabrice, Bour, Pierre, Vaillant, Fanny, Amraoui, Sana, Dubois, Rémi, Ritter, Philippe, Haïssaguerre, Michel, Hocini, Mélèze, Bernus, Olivier, Tebebi, Pamela, Burks, Scott, Milo, Blerta, Gertner, Michael, Zhang, Jimin, Wong, Andrew, Liu, Yu, Kheirolomoom, Azadeh, Seo, Jai, Watson, Katherine, Zhang, Hua, Foiret, Josquin, Borowsky, Alexander, Xu, Doudou, Thanou, Maya, Centelles, Miguell, Wright, Mike, Amrahli, Maral, So, Po-Wah, Gedroyc, Wladyslaw, Kneepkens, Esther, Heijman, Edwin, Keupp, Jochen, Weiss, Steffen, Nicolay, Klaas, Grüll, Holger, Nagle, Matthew, Nikolaeva, Anastasia V., Terzi, Marina E., Tsysar, Sergey A., Cunitz, Bryan, Mourad, Pierre, Downs, Matthew, Yang, Georgiana, Wang, Qi, Chen, Johnny, Farry, Justin, Dixon, Adam, Du, Zhongmin, Dhanaliwala, Ali, Hossack, John, Ranjan, Ashish, Maples, Danny, Wardlow, Rachel, Malayer, Jerry, Ramachandran, Akhilesh, Namba, Hirofumi, Kawasaki, Motohiro, Izumi, Masashi, Kiyasu, Katsuhito, Takemasa, Ryuichi, Ikeuchi, Masahiko, Ushida, Takahiro, Crake, Calum, Kothapalli, Satya V. V. N., Leighton, Wan, Wang, Zhaorui, Gach, H. Michael, Straube, William, Altman, Michael, Kim, Young-sun, Lim, Hyo Keun, Rhim, Hyunchul, van Breugel, Johanna, Braat, Manon, Moonen, Chrit, van den Bosch, Maurice, Ries, Mario, Marrocchio, Cristina, Dababou, Susan, Lee, Jae Young, Chung, Hyun Hoon, Kang, Soo Yeon, Kang, Kook Jin, Son, Keon Ho, Zhang, Dandan, Plata, Juan, Jones, Peter, Pascal-Tenorio, Aurea, Bouley, Donna, Bond, Aaron, Dallapiazza, Robert, Huss, Diane, Warren, Amy, Sperling, Scott, Gwinn, Ryder, Shah, Binit, Elias, W. Jeff, Curley, Colleen, Zhang, Ying, Negron, Karina, Abounader, Roger, Samiotaki, Gesthimani, Tu, Tsang-Wei, Papadakis, Georgios, Hammoud, Dima, Silvestrini, Matthew, Wolfram, Frank, Güllmar, Daniel, Reichenbach, Juergen, Hofmann, Denis, Böttcher, Joachim, Schubert, Harald, Lesser, Thomas G., Almquist, Scott, Camarena, Francisco, Jiménez-Gambín, Sergio, Jiménez, Noé, Chang, Jin Woo, Chaplin, Vandiver, Griesenauer, Rebekah, Miga, Michael, Ellens, Nicholas, Airan, Raag, Quinones-Hinojosa, Alfredo, Farahani, Keyvan, Feng, Xue, Fielden, Samuel, Zhao, Li, Wintermark, Max, Meyer, Craig, Guo, Sijia, Lu, Xin, Zhuo, Jiachen, Xu, Su, Gullapalli, Rao, Gandhi, Dheeraj, Brokman, Omer, Baek, Hongchae, Kim, Hyungmin, Leung, Steven, Webb, Taylor, Vykhodtseva, Natalia, Nguyen, Thai-Son, Park, Chang Kyu, Park, Sang Man, Jung, Na Young, Kim, Min Soo, Chang, Won Seok, Jung, Hyun Ho, Plaksin, Michael, Weissler, Yoni, Shoham, Shy, Kimmel, Eitan, Rosnitskiy, Pavel B., Krupa, Steve, Hazan, Eilon, Naor, Omer, Levy, Yoav, Maimon, Noam, Brosh, Inbar, Kahn, Itamar, Cahill, Jessica, Colas, Elodie Constanciel, Wydra, Adrian, Maev, Roman, Aly, Amirah, Sesenoglu-Laird, Ozge, Padegimas, Linas, Cooper, Mark, Waszczak, Barbara, Tehrani, Seruz, Slingluff, Craig, Larner, James, Andarawewa, Kumari, Ozhinsky, Eugene, Shah, Rutwik, Krug, Roland, Deckers, Roel, Linn, Sabine, Suelmann, Britt, Witkamp, Arjen, Vaessen, Paul, van Diest, Paul, Bartels, Lambertus W., Bos, Clemens, Borys, Nicolas, Storm, Gert, Van der Wall, Elsken, Farr, Navid, Alnazeer, Moez, Katti, Prateek, Wood, Bradford, Farrer, Alexis, Ferrer, Cyril, de Senneville, Baudouin Denis, van Stralen, Marijn, Liu, Jingfei, Leach, J. Kent, Zidowitz, Stephan, Lee, Hsin-Lun, Hsu, Fang-Chi, Kuo, Chia-Chun, Jeng, Shiu-Chen, Chen, Tung-Ho, Yang, Nai-Yi, Chiou, Jeng-Fong, Kao, Yi-tzu, Pan, Chia-Hsin, Wu, Jing-Fu, Tsai, Yi-Chieh, Johnson, Sara, Li, Dawei, He, Ye, Karakitsios, Ioannis, Schwenke, Michael, Demedts, Daniel, Xiao, Xu, Cavin, Ian, Minalga, Emilee, Merrill, Robb, Hadley, Rock, Ramaekers, Pascal, de Greef, Martijn, Shahriari, Kian, Parvizi, Mohammad Hossein, Asadnia, Kiana, Chamanara, Marzieh, Kamrava, Seyed Kamran, Chabok, Hamid Reza, Stein, Ruben, Muller, Sébastien, Tan, Jeremy, Zachiu, Cornel, Erasmus, Hans-Peter, Van Arsdell, Glen, Benson, Lee, Jang, Kee W., Angstadt, Mary, Lewis, Bobbi, McLean, Hailey, Hoogenboom, Martijn, Eikelenboom, Dylan, den Brok, Martijn, Wesseling, Pieter, Heerschap, Arend, Fütterer, Jurgen, Adema, Gosse, Wang, Kevin, Zhong, Pei, Joy, Joyce, McLeod, Helen, Kim, Harry, Lewis, Matthew, Ozilgen, Arda, Zahos, Peter, Coughlin, Dezba, Tang, Xinyan, Lotz, Jeff, Jedruszczuk, Kathleen, Gulati, Amitabh, Solomon, Stephen, Kaye, Elena, Mugler, John, Barbato, Gaetano, Scoarughi, Gian Luca, Corso, Cristiano, Gorgone, Alessandro, Migliore, Ilaria Giuseppina, Larrabee, Zachary, Hananel, Arik, Aubry, Jean-Francois, Negussie, Ayele, Wilson, Emmanuel, Seifabadi, Reza, Moon, Hyungwon, Kang, Jeeun, Sim, Changbeom, Chang, Jin Ho, Kim, Hyuncheol, Lee, Hak Jong, Sasaki, Noboru, Takiguchi, Mitsuyoshi, Sebeke, Lukas, Luo, Xi, de Jager, Bram, Heemels, Maurice, Abraham, Christopher, Curiel, Laura, Berriet, Rémi, Janát-Amsbury, Margit, Corea, Joseph, Ye, Patrick Peiyong, Arias, Ana Clauda, Lustig, Micheal, and Svedin, Bryant

Subjects
lcsh:Medical physics. Medical radiology. Nuclear medicine, Fibroadenomata, Cryo-ablation, High-intensity focused ultrasound, Ablative techniques, lcsh:R895-920, Review, Meeting Abstracts, Laser ablation
Abstract

Introduction Breast fibroadenomata (FAD) are benign lesions which occur in about 10 % of all women. Diagnosis is made by triple assessment (physical examination, imaging and/or histopathology/cytology). For a definitive diagnosis of FAD, the treatment is conservative unless the patient is symptomatic. For symptomatic patients, the lumps can be surgically excised or removed interventionally by vacuum-assisted mammotomy (VAM). Ablative techniques like high-intensity focused ultrasound (HIFU), cryo-ablation and laser ablation have also been used for the treatment of FAD, providing a minimally invasive treatment without scarring or poor cosmesis. This review summarises current trials using minimally invasive ablative techniques in the treatment of breast FAD. Methods A comprehensive review of studies using minimally invasive ablative techniques was performed. Results There are currently several trials completed or recruiting patients using HIFU, cryo-ablation and laser ablation in the treatment of breast FAD. The results look very promising but cannot be compared at this point due to heterogeneity between studies. Conclusion Minimally invasive ablative techniques like HIFU, cryo-ablation and laser ablation are promising in the treatment of breast FAD. Future trials should be randomised and contain larger numbers of patients to determine the effectiveness of ablative techniques with more precision.

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28. Histological characterization of HIFU lesions.

Author

Rivens I, Jayadewa C, Mouratidis P, and Ter Haar G

Subjects
Animals, Rats, Liver pathology, Male, Rats, Sprague-Dawley, High-Intensity Focused Ultrasound Ablation methods
Abstract

Background: High intensity focused ultrasound (HIFU) can destroy tissue by thermal ablation which may be accompanied by acoustic cavitation and/or tissue water boiling, but the biological and histological effects of these treatments have not been fully documented. Here, detailed histological analysis over time using well characterized HIFU exposures in in vivo rat livers is described., Methods: Exposures used invoked either (i) thermal, with acoustic cavitation and/or tissue water boiling or (ii) predominantly thermal damage. Cavitation activity was detected using both active and passive methods. Histological assessment involved hematoxylin and eosin (H&E), picrosirius red and immunohistochemical staining., Results: Distinct concentric damage regions were identified after HIFU exposures. The outermost ring showed a red H&E-stained rim that was characterized by hemorrhage. The adjacent inner band appeared white due to increased extracellular spaces. The morphology of the next zone depended on the exposure. Where there was no tissue acoustic cavitation/water boiling, this was the lesion center, in which heat-fixed cells were seen. Where acoustic cavitation/boiling occurred, a centermost zone with irregular holes up to several hundred microns across was seen. Cleaved caspase-3 and Hsp70 staining in the periphery of both types of HIFU exposures was seen within the outermost ring of hemorrhage, where an inflammatory response was also observed. By day 7, a distinct acellular region in the center of the HIFU lesions had been created., Conclusions: These results identify the morphological effects and elucidate the similarities and differences of HIFU-induced thermal lesions in the presence or absence of acoustic cavitation/tissue water boiling.

Published
2024
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29. Transfection of indoleamine 2,3 dioxygenase in primary endothelial cells.

Author

Mouratidis PX and George AJ

Subjects
Cell Separation, Cells, Cultured, Electroporation, Endothelial Cells cytology, Enzyme Assays, Humans, Plasmids genetics, Saphenous Vein cytology, Endothelial Cells enzymology, Indoleamine-Pyrrole 2,3,-Dioxygenase metabolism, Transfection methods
Abstract

The endothelial cell plays a central role in the control of inflammatory processes. The recruitment of inflammatory leucocytes into the blood vessels is controlled by the expression of adhesion molecules on the endothelium as well as the secretion and presentation of chemokines. Indoleamine 2,3 dioxygenase (IDO) is an enzyme that metabolises tryptophan and is known to be central in the regulation of immune responses. IDO can be expressed on endothelial cells and can alter T-cell responses to the endothelium. We show that IDO can be readily transfected in primary endothelial cells and detail a method to determine the activity of the transfected protein.

Published
2010
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