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34 results on '"Mourelo S"'

15. Evaluación de la tasa de detección de la recidiva local y de cuerpo completo mediante la valoración integrada de la PET/RM con [18F]F-PSMA-1007 de pacientes con cáncer de próstata tratados con prostatectomía con recidiva bioquímica muy baja (<0,5ng/ml). Implicaciones terapéuticas

Author

Garcia, J.R., Compte, A., Pastor, J., Mourelo, S., Mont, L., Bassa, P., Llinares, E., Soler, M., Valls, E., Blanch, T., and Riera, E.

Abstract

Analizar la eficacia de la valoración integrada [18F]F-PSMA-1007 PET/RM en la detección precoz (PSA<0,5ng/ml) de la recidiva local (RL) tras prostatectomía.

Published
2024
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32. El dinamismo místico en el pensamiento de Blondel

Author

García-Mourelo, S. (Santiago)

Subjects
Maurice Blondel, Filosofía, Mística
Abstract

El presente artículo muestra la dinámica de la vida mística en el trasfondo de la obra del joven Blondel. La sabiduría a la que aspira la reflexión filosófica es una de las gracias del camino místico; este no está margen de la razón, sino que la excede y prolonga hacia sus más altas cotas. La filosofía de la acción del maestro de Aix ofrece, a parte hominis, no solo una vía racionalmente posible para su consecución –con todas sus potencialidades apologéticas–, sino, también, una propuesta vital para asimilar el don recibido, a parte Dei, en la totalidad de la vida: pensamiento, voluntad y consistencia ontológica.

Published
2019

33. HER2 blockade in metastatic collecting duct carcinoma (CDC) of the kidney: a case report.

Author

Bronchud MH, Castillo S, Escriva de Romaní S, Mourelo S, Fernández A, Baena C, Murillo J, Julia JC, Esquius J, Romero R, and Andreu X

Subjects
Administration, Oral, Aged, Antibodies, Monoclonal, Humanized administration & dosage, Capecitabine, Carcinoma, Renal Cell pathology, Deoxycytidine administration & dosage, Deoxycytidine analogs & derivatives, Fluorouracil administration & dosage, Fluorouracil analogs & derivatives, Humans, Injections, Intravenous, Kidney Neoplasms pathology, Lapatinib, Male, Quinazolines administration & dosage, Trastuzumab, Treatment Outcome, Antineoplastic Combined Chemotherapy Protocols administration & dosage, Brain Neoplasms prevention & control, Brain Neoplasms secondary, Carcinoma, Renal Cell drug therapy, Carcinoma, Renal Cell secondary, Kidney Neoplasms drug therapy, Receptor, ErbB-2 antagonists & inhibitors
Abstract

Background: Collecting duct carcinoma of the kidney (CDC) is a rare cancer associated with bad prognosis and, at present, with no specific effective therapies., Case Report: We report a clinical case with disseminated highgrade CDC presenting with widespread metastasis to both lungs, pelvic bones, axial skeleton, and the central nervous system (posterior fossa, both hemispheres and pituitary-hypothalamic). The primary tumor in the kidney was demonstrated (by fluorescence in situ hybridization and immunohistochemistry with Herceptest (3+ score)) to significantly overexpress HER2. Critically ill at presentation, the patient received oral capecitabine together with double HER2 blockade with both intravenous trastuzumab and oral lapatinib. His clinical response was a dramatic improvement and a progressive decline in the radiological size of all of his multiple cancer lesions., Conclusion: Double HER2 blockade is an effective therapy in disseminated CDC even in the presence of brain metastases.

Published
2012
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