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420 results on '"Muhammad, Hayat"'

1. The Precarity of Progress: Implications of a Shifting Gendered Division of Labor for Relationships and Well-Being as a Function of Country-Level Gender Equality

Author

Fisher, Alexandra N., Ryan, Michelle K., Liao, Yuan-Hsi, Mikołajczak, Gosia, Riedijk, Larisa, Leander, N. Pontus, Abakoumkin, Georgios, Abdul Khaiyom, Jamilah Hanum, Ahmedi, Vjollca, Agostini, Maximilian, Atta, Moshin, Bagci, Sabahat Cigdem, J. Bélanger, Jocelyn, Berisha Kida, Edona, B. I. Bernardo, Allan, Chobthamkit, Phatthanakit, Choi, Hoon-Seok, Cristea, Mioara, Damnjanovic, Kaja, Danyliuk, Ivan, Di Santo, Daniela, M. Douglas, Karen, Enea, Violeta, J. Fitzsimons, Gavan, Gómez, Ángel, Gützkow, Ben, Hamaidia, Ali, Helmy, Mai, Hudiyana, Joevarian, Jovanović, Veljko, Jovanović, Veljko, Kende, Anna, Keng, Shian-Ling, Kieu, Tra Thi Thanh, Koc, Yasin, Kreienkamp, Jannis, Kurapov, Anton, Lantos, Nóra Anna, P. Lemay, Edward, Lueders, Adrian, Malik, Najma Iqbal, O. McCabe, Kira, Mehulić, Jasmina, Molinario, Erica, Moyano, Manuel, Muhammad, Hayat, Muluk, Hamdi, F. Nisa, Claudia, Nyúl, Boglárka, A. O’Keefe, Paul, Olivias Osuna, Jose Javier, Osin, Evgeny, Park, Joonha, Pica, Gennaro, Pierro, Antonio, Rees, Jonas, Reitsema, Anne Margit, Rullo, Marika, Samekin, Adil, M. Schumpe, Birga, A. Selim, Heyla, Stanton, Michael Vicente, Tseliou, Eleftheria, R vanDellen, Michelle, Vázquez, Alexandra, Wollast, Robin, Yeung, Victoria Wai-Lan, Zand, Somayeh, Žeželj, Iris Lav, and Zúñiga, Claudia

Published
2024
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2. Dosage constraint of the ribosome-associated molecular chaperone drives the evolution and fates of its duplicates in bacteria

Author

Tianyu Wan, Li Zhuo, Zhuo Pan, Rui-yun Chen, Han Ma, Ying Cao, Jianing Wang, Jing-jing Wang, Wei-feng Hu, Ya-jun Lai, Muhammad Hayat, and Yue-zhong Li

Subjects
trigger factor, gene duplication, dosage constraint, ribosome binding, holdase, Microbiology, QR1-502
Abstract

ABSTRACT Gene duplication events happen prevalently during evolution, and the mechanisms governing the loss or retention of duplicated genes are mostly elusive. Our genome scanning analysis revealed that trigger factor (TF), the one and only bacterial ribosome-associated molecular chaperone, is singly copied in virtually every bacterium except for a very few that possess two or more copies. However, even in these exceptions, only one complete TF copy exists, while other homologs lack the N-terminal domain that contains the conserved ribosome binding site (RBS) motif. Consistently, we demonstrated that the overproduction of the N-terminal complete TF proteins is detrimental to the cell, which can be rescued by removing the N-terminal domain. Our findings also indicated that TF overproduction leads to a decrease in protein productivity and profile changes in proteome due to its characteristic ribosome binding and holdase activities. Additionally, these N-terminal deficient TF homologs in bacteria with multiple TF homologs partition the function of TF via subfunctionalization. Our results revealed that TF is subjected to a dosage constraint that originates from its own intrinsic functions, which may drive the evolution and fates of duplicated TFs in bacteria.IMPORTANCEGene duplication events presumably occur in tig, which encodes the ribosome-associated molecular chaperone trigger factor (TF). However, TF is singly copied in virtually every bacterium, and these exceptions with multiple TF homologs always retain only one complete copy while other homologs lack the N-terminal domain. Here, we reveal the manner and mechanism underlying the evolution and fates of TF duplicates in bacteria. We discovered that the mutation-to-loss or retention-to-sub/neofunctionalization of TF duplicates is associated with the dosage constraint of N-terminal complete TF. The dosage constraint of TF is attributed to its characteristic ribosome binding and substrate-holding activities, causing a decrease in protein productivity and profile changes in cellular proteome.

Published
2024
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5. Characteristics and outcomes of COVID-19 patients admitted to hospital with and without respiratory symptoms

Author

Barbara Wanjiru Citarella, Christiana Kartsonaki, Elsa D. Ibáñez-Prada, Bronner P. Gonçalves, Joaquin Baruch, Martina Escher, Mark G. Pritchard, Jia Wei, Fred Philippy, Andrew Dagens, Matthew Hall, James Lee, Demetrios James Kutsogiannis, Evert-Jan Wils, Marília Andreia Fernandes, Bharath Kumar Tirupakuzhi Vijayaraghavan, Prasan Kumar Panda, Ignacio Martin-Loeches, Shinichiro Ohshimo, Arie Zainul Fatoni, Peter Horby, Jake Dunning, Jordi Rello, Laura Merson, Amanda Rojek, Michel Vaillant, Piero Olliaro, Luis Felipe Reyes, S.A. Moharam, Sabriya Abdalasalam, Alaa Abdalfattah Abdalhadi, Naana Reyam Abdalla, Walaa Abdalla, Almthani Hamza Abdalrheem, Ashraf Abdalsalam, Saedah Abdeewi, Esraa Hassan Abdelgaum, Mohamed Abdelhalim, Mohammed Abdelkabir, Israa Abdelrahman, Sheryl Ann Abdukahil, Lamees Adil Abdulbaqi, Salaheddin Abdulhamid, Widyan Abdulhamid, Nurul Najmee Abdulkadir, Eman Abdulwahed, Rawad Abdunabi, Ryuzo Abe, Laurent Abel, Ahmed Mohammed Abodina, Amal Abrous, Lara Absil, Kamal Abu Jabal, Nashat Abu Salah, Abdurraouf Abusalama, Tareg Abdallah Abuzaid, Subhash Acharya, Andrew Acker, Elisabeth Adam, Safia Adem, Manuella Ademnou, Francisca Adewhajah, Diana Adrião, Anthony Afum-Adjei Awuah, Melvin Agbogbatey, Saleh Al Ageel, Aya Mustafa Ahmed, Musaab Mohammed Ahmed, Shakeel Ahmed, Zainab Ahmed Alaraji, Abdulrahman Ahmed Elhefnawy Enan, Reham Abdelhamid Ahmed Khalil, Ali Mostafa Ahmed Mohamed Abdelaziz, Kate Ainscough, Eka Airlangga, Tharwat Aisa, Ali Aisha, Bugila Aisha, Ali Ait Hssain, Younes Ait Tamlihat, Takako Akimoto, Ernita Akmal, Chika Akwani, Eman Al Qasim, Ahmed Alajeeli, Ahmed Alali, Razi Alalqam, Aliya Mohammed Alameen, Mohammed Al-Aquily, Zinah A. Alaraji, Khalid Albakry, Safa Albatni, Angela Alberti, Osama Aldabbourosama, Tala Al-dabbous, Amer Aldhalia, Abdulkarim Aldoukali, Senthilkumar Alegesan, Marta Alessi, Beatrice Alex, Kévin Alexandre, Abdulrahman Al-Fares, Asil Alflite, Huda Alfoudri, Qamrah Alhadad, Hoda Salem Alhaddad, Maali Khalid Mohamed Abdalla Alhasan, Ahmad Nabil Alhouri, Hasan Alhouri, Adam Ali, Imran Ali, Maha TagElser Mohammed Ali, Syed Ali Abbas, Yomna Ali Abdelghafar, Naseem Ali Sheikh, Kazali Enagnon Alidjnou, Mahmoud Aljadi, Sarah Aljamal, Mohammed Alkahlout, Akram Alkaseek, Qabas Alkhafajee, Clotilde Allavena, Nathalie Allou, Lana Almasri, Abdulrahman Almjersah, Raja Ahmed Alqandouz, Walaa Alrfaea, Moayad Alrifaee, Rawan Alsaadi, Yousef Al-Saba'a, Entisar Alshareea, Eslam Alshenawy, Aneela Altaf, João Melo Alves, João Alves, Rita Alves, Joana Alves Cabrita, Maria Amaral, Amro Essam Amer, Nur Amira, Amos Amoako Adusei, John Amuasi, Roberto Andini, Claire Andrejak, Andrea Angheben, François Angoulvant, Sophia Ankrah, Séverine Ansart, Sivanesen Anthonidass, Massimo Antonelli, Carlos Alexandre Antunes de Brito, Ardiyan Apriyana, Yaseen Arabi, Irene Aragao, Francisco Arancibia, Carolline Araujo, Antonio Arcadipane, Patrick Archambault, Lukas Arenz, Jean-Benoît Arlet, Christel Arnold-Day, Lovkesh Arora, Rakesh Arora, Elise Artaud-Macari, Diptesh Aryal, Angel Asensio, Elizabeth A. Ashley, Muhammad Ashraf, Muhammad Sheharyar Ashraf, Abir Ben Ashur, Franklin Asiedu-Bekoe, Namra Asif, Mohammad Asim, Grace Assi, Jean Baptiste Assie, Amirul Asyraf, Fouda Atangana, Ahmed Atia, Minahel Atif, Asia Atif Abdelrhman Abdallahrs, Anika Atique, Moad Atlowly, AM Udara Lakshan Attanyake, Johann Auchabie, Hugues Aumaitre, Adrien Auvet, Abdelmalek Awad Ali Mohammed, Eyvind W. Axelsen, Ared Ayad, Ahmed Ayman Hassan Helmi, Laurène Azemar, Mohammed Azizeldin, Cecile Azoulay, Hakeem Babatunde, Benjamin Bach, Delphine Bachelet, Claudine Badr, Roar Bævre-Jensen, Nadia Baig, John Kenneth Baillie, J Kevin Baird, Erica Bak, Agamemnon Bakakos, Nazreen Abu Bakar, Hibah Bileid Bakeer, Ashraf Bakri, Andriy Bal, Mohanaprasanth Balakrishnan, Irene Bandoh, Firouzé Bani-Sadr, Renata Barbalho, Nicholas Yuri Barbosa, Wendy S. Barclay, Saef Umar Barnett, Michaela Barnikel, Helena Barrasa, Cleide Barrigoto, Marie Bartoli, Joaquín Baruch, Romain Basmaci, Muhammad Fadhli Hassin Basri, AbdAlkarim Batool, Denise Battaglini, Jules Bauer, Diego Fernando Bautista Rincon, Denisse Bazan Dow, Abigail Beane, Alexandra Bedossa, Ker Hong Bee, Husna Begum, Sylvie Behilill, Albertus Beishuizen, Aleksandr Beljantsev, David Bellemare, Anna Beltrame, Beatriz Amorim Beltrão, Marine Beluze, Nicolas Benech, Lionel Eric Benjiman, Suzanne Bennett, Luís Bento, Jan-Erik Berdal, Lamis Berdeweel, Delphine Bergeaud, Hazel Bergin, Giulia Bertoli, Lorenzo Bertolino, Simon Bessis, Sybille Bevilcaqua, Karine Bezulier, Amar Bhatt, Krishna Bhavsar, Isabella Bianchi, Claudia Bianco, Sandra Bichoka, Farah Nadiah Bidin, Felwa Bin Humaid, Mohd Nazlin Bin Kamarudin, Muhannud Binnawara, Zeno Bisoffi, Patrick Biston, Laurent Bitker, Mustapha Bittaye, Jonathan Bitton, Pablo Blanco-Schweizer, Catherine Blier, Frank Bloos, Mathieu Blot, Filomena Boccia, Laetitia Bodenes, Debby Bogaert, Anne-Hélène Boivin, Ariel Bolanga, Isabela Bolaños, Pierre-Adrien Bolze, François Bompart, Aurelius Bonifasius, Joe Bonney, Diogo Borges, Raphaël Borie, Hans Martin Bosse, Elisabeth Botelho-Nevers, Lila Bouadma, Olivier Bouchaud, Sabelline Bouchez, Damien Bouhour, Kévin Bouiller, Laurence Bouillet, Camile Bouisse, Latsaniphone Bountthasavong, Anne-Sophie Boureau, John Bourke, Maude Bouscambert, Aurore Bousquet, Marielle Boyer-Besseyre, Maria Boylan, Fernando Augusto Bozza, Axelle Braconnier, Cynthia Braga, Timo Brandenburger, Filipa Brás Monteiro, Luca Brazzi, Dorothy Breen, Patrick Breen, David Brewster, Kathy Brickell, Tessa Broadley, Helen Brotherton, Alex Browne, Nicolas Brozzi, Sonja Hjellegjerde Brunvoll, Marjolein Brusse-Keizer, Petra Bryda, Nina Buchtele, Polina Bugaeva, Marielle Buisson, Danilo Buonsenso, Erlina Burhan, Donald Buri, Aidan Burrell, Ingrid G. Bustos, Denis Butnaru, André Cabie, Susana Cabral, Joana Cabrita, Eder Caceres, Cyril Cadoz, Rui Caetano Garcês, Kate Calligy, Jose Andres Calvache, João Camões, Valentine Campana, Paul Campbell, Josie Campisi, Cecilia Canepa, Mireia Cantero, Janice Caoili, Pauline Caraux-Paz, Sheila Cárcel, Filipa Cardoso, Filipe Cardoso, Nelson Cardoso, Sofia Cardoso, Simone Carelli, Nicolas Carlier, Thierry Carmoi, Gayle Carney, Inês Carqueja, Marie-Christine Carret, François Martin Carrier, Ida Carroll, Gail Carson, Maire-Laure Casanova, Mariana Cascão, Siobhan Casey, José Casimiro, Bailey Cassandra, Silvia Castañeda, Nidyanara Castanheira, Guylaine Castor-Alexandre, Ivo Castro, Ana Catarino, François-Xavier Catherine, Paolo Cattaneo, Roberta Cavalin, Giulio Giovanni Cavalli, Alexandros Cavayas, Adrian Ceccato, Masaneh Ceesay, Shelby Cerkovnik, Minerva Cervantes-Gonzalez, Muge Cevik, Anissa Chair, Catherine Chakveatze, Adrienne Chan, Meera Chand, Jean-Marc Chapplain, Charlotte Charpentier, Julie Chas, Muhammad Mobin Chaudry, Jonathan Samuel Chávez Iñiguez, Anjellica Chen, Yih-Sharng Chen, Léo Chenard, Matthew Pellan Cheng, Antoine Cheret, Thibault Chiarabini, Julian Chica, Suresh Kumar Chidambaram, Leong Chin Tho, Catherine Chirouze, Davide Chiumello, Sung-Min Cho, Bernard Cholley, Danoy Chommanam, Marie-Charlotte Chopin, Yock Ping Chow, Ting Soo Chow, Nathaniel Christy, Hiu Jian Chua, Jonathan Chua, Jose Pedro Cidade, José Miguel Cisneros Herreros, Anna Ciullo, Jennifer Clarke, Rolando Claure-Del Granado, Sara Clohisey, Cassidy Codan, Caitriona Cody, Jennifer Coles, Megan Coles, Gwenhaël Colin, Michael Collins, Pamela Combs, Jennifer Connolly, Marie Connor, Anne Conrad, Elaine Conway, Graham S. Cooke, Hugues Cordel, Amanda Corley, Sabine Cornelis, Alexander Daniel Cornet, Arianne Joy Corpuz, Andrea Cortegiani, Grégory Corvaisier, Camille Couffignal, Sandrine Couffin-Cadiergues, Roxane Courtois, Stéphanie Cousse, Juthaporn Cowan, Rachel Cregan, Gloria Crowl, Jonathan Crump, Claudina Cruz, Marc Csete, Ailbhe Cullen, Matthew Cummings, Gerard Curley, Elodie Curlier, Colleen Curran, Paula Custodio, Ana da Silva Filipe, Charlene Da Silveira, Al-Awwab Dabaliz, John Arne Dahl, Darren Dahly, Umberto D'Alessandro, Peter Daley, Zaina Dalloul, Heidi Dalton, Jo Dalton, Seamus Daly, Juliana Damas, Joycelyn Dame, Cammandji Damien, Nick Daneman, Jorge Dantas, Frédérick D'Aragon, Gillian de Loughry, Diego de Mendoza, Etienne De Montmollin, Rafael Freitas de Oliveira França, Ana Isabel de Pinho Oliveira, Rosanna De Rosa, Cristina De Rose, Thushan de Silva, Peter de Vries, Jillian Deacon, David Dean, Alexa Debard, Bianca DeBenedictis, Marie-Pierre Debray, Nathalie DeCastro, William Dechert, Romain Decours, Eve Defous, Isabelle Delacroix, Alexandre Delamou, Eric Delaveuve, Karen Delavigne, Nathalie M. Delfos, Ionna Deligiannis, Andrea Dell'Amore, Christelle Delmas, Pierre Delobel, Corine Delsing, Elisa Demonchy, Emmanuelle Denis, Dominique Deplanque, Pieter Depuydt, Diane Descamps, Mathilde Desvallées, Santi Dewayanti, Pathik Dhangar, Alpha Diallo, Souleymane Taran Diallo, Sylvain Diamantis, André Dias, Fernanda Dias Da Silva, Rodrigo Diaz, Juan Jose Diaz, Priscila Diaz, Bakary K. Dibba, Kévin Didier, Jean-Luc Diehl, Wim Dieperink, Jérôme Dimet, Vincent Dinot, Fara Diop, Alphonsine Diouf, Yael Dishon, Cedric Djadda, Félix Djossou, Annemarie B. Docherty, Helen Doherty, Arjen M. Dondorp, Christl A. Donnelly, Yoann Donohue, Sean Donohue, Peter Doran, Céline Dorival, Eric D'Ortenzio, Yash Doshi, Phouvieng Douangdala, James Joshua Douglas, Renee Douma, Nathalie Dournon, Joanne Downey, Mark Downing, Thomas Drake, Aoife Driscoll, Ibrahim Kwaku Duah, Claudio Duarte Fonseca, Vincent Dubee, François Dubos, Audrey Dubot-Pérès, Alexandre Ducancelle, Toni Duculan, Susanne Dudman, Abhijit Duggal, Paul Dunand, Mathilde Duplaix, Emanuele Durante-Mangoni, Lucian Durham, III, Bertrand Dussol, Juliette Duthoit, Xavier Duval, Anne Margarita Dyrhol-Riise, Sim Choon Ean, Ada Ebo, Marco Echeverria-Villalobos, Michael Edelstein, Siobhan Egan, Linn Margrete Eggesbø, Khadeja Ehzaz, Carla Eira, Mohammed El Sanharawi, Marwan El Sayed, Mohammed Elabid, Mohamed Bashir Elagili, Subbarao Elapavaluru, Mohammad Elbahnasawy, Sohail Elboshra, Brigitte Elharrar, Jacobien Ellerbroek, Merete Ellingjord-Dale, Hamida ELMagrahi, Mohammad Muatasm Elmubark, Loubna Elotmani, Lauren Eloundou, Philippine Eloy, Basma Elshaikhy, Tarek Elshazly, Wafa Elsokni, Aml Ahmed Eltayeb, Iqbal Elyazar, Zarief Kamel Emad, Hussein Embarek, Isabelle Enderle, Tomoyuki Endo, Gervais Eneli, Chan Chee Eng, Ilka Engelmann, Vincent Enouf, Olivier Epaulard, Haneen Esaadi, Mariano Esperatti, Hélène Esperou, Catarina Espírito Santo, Marina Esposito-Farese, Rachel Essaka, Lorinda Essuman, João Estevão, Manuel Etienne, Anna Greti Everding, Mirjam Evers, Isabelle Fabre, Marc Fabre, Ismaila Fadera, Asgad Osman Abdalla Fadlalla, Amna Faheem, Arabella Fahy, Cameron J. Fairfield, Zul Fakar, Komal Fareed, Pedro Faria, Ahmed Farooq, Hanan Fateena, Mohamed Fathi, Salem Fatima, Karine Faure, Raphaël Favory, Mohamed Fayed, Niamh Feely, Jorge Fernandes, Susana Fernandes, François-Xavier Ferrand, Eglantine Ferrand Devouge, Joana Ferrão, Mário Ferraz, Benigno Ferreira, Isabel Ferreira, Bernardo Ferreira, Sílvia Ferreira, Nicolas Ferriere, Céline Ficko, Claudia Figueiredo-Mello, William Finlayson, Thomas Flament, Tom Fletcher, Aline-Marie Florence, Letizia Lucia Florio, Brigid Flynn, Deirdre Flynn, Jean Foley, Victor Fomin, Tatiana Fonseca, Patricia Fontela, Karen Forrest, Simon Forsyth, Denise Foster, Giuseppe Foti, Berline Fotso, Erwan Fourn, Robert A. Fowler, Marianne Fraher, Diego Franch-Llasat, Christophe Fraser, John F. Fraser, Marcela Vieira Freire, Ana Freitas Ribeiro, Craig French, Caren Friedrich, Ricardo Fritz, Stéphanie Fry, Nora Fuentes, Masahiro Fukuda, G. Argin, Valérie Gaborieau, Rostane Gaci, Massimo Gagliardi, Jean-Charles Gagnard, Amandine Gagneux-Brunon, Abdou Gai, Sérgio Gaião, Linda Gail Skeie, Adham Mohamed Galal Mohamed Ramadan, Phil Gallagher, Carrol Gamble, Yasmin Gani, Arthur Garan, Rebekha Garcia, Julia Garcia-Diaz, Esteban Garcia-Gallo, Navya Garimella, Denis Garot, Valérie Garrait, Basanta Gauli, Anatoliy Gavrylov, Alexandre Gaymard, Johannes Gebauer, Eva Geraud, Louis Gerbaud Morlaes, Nuno Germano, Malak Ghemmeid, Praveen Kumar Ghisulal, Jade Ghosn, Marco Giani, Tristan Gigante, Elaine Gilroy, Guillermo Giordano, Michelle Girvan, Valérie Gissot, Gezy Giwangkancana, Daniel Glikman, Petr Glybochko, Eric Gnall, Geraldine Goco, François Goehringer, Siri Goepel, Jean-Christophe Goffard, Jin Yi Goh, Brigitta Golács, Jonathan Golob, Kyle Gomez, Joan Gómez-Junyent, Marie Gominet, Alicia Gonzalez, Patricia Gordon, Isabelle Gorenne, Laure Goubert, Cécile Goujard, Tiphaine Goulenok, Margarite Grable, Jeronimo Graf, Edward Wilson Grandin, Pascal Granier, Giacomo Grasselli, Lorenzo Grazioli, Christopher A. Green, Courtney Greene, William Greenhalf, Segolène Greffe, Domenico Luca Grieco, Matthew Griffee, Fiona Griffiths, Ioana Grigoras, Albert Groenendijk, Fassou Mathias Grovogui, Heidi Gruner, Yusing Gu, Jérémie Guedj, Martin Guego, Anne-Marie Guerguerian, Daniela Guerreiro, Romain Guery, Anne Guillaumot, Laurent Guilleminault, Maisa Guimarães de Castro, Thomas Guimard, Marieke Haalboom, Daniel Haber, Ali Hachemi, Abdurrahman Haddud, Nadir Hadri, Wael Hafez, Fakhir Raza Haidri, Fatima Mhd Rida Hajij, Sheeba Hakak, Adam Hall, Sophie Halpin, Shaher Hamdan, Abdelhafeez Hamdi, Jawad Hameed, Ansley Hamer, Raph L. Hamers, Rebecca Hamidfar, Bato Hammarström, Naomi Hammond, Terese Hammond, Lim Yuen Han, Matly Hanan, Rashan Haniffa, Kok Wei Hao, Hayley Hardwick, Ewen M. Harrison, Janet Harrison, Samuel Bernard Ekow Harrison, Alan Hartman, Sulieman Hasan, Mohammad Ali Nabil Hasan, Mohd Shahnaz Hasan, Junaid Hashmi, Madiha Hashmi, Amoni Hassan, Ebtisam Hassanin, Muhammad Hayat, Ailbhe Hayes, Leanne Hays, Jan Heerman, Lars Heggelund, Ahmed Helmi, Ross Hendry, Martina Hennessy, Aquiles Rodrigo Henriquez-Trujillo, Maxime Hentzien, Diana Hernandez, Andrew Hershey, Liv Hesstvedt, Astarini Hidayah, Eibhlin Higgins, Rupert Higgins, Samuel Hinton, Hiroaki Hiraiwa, Haider Hirkani, Hikombo Hitoto, Antonia Ho, Yi Bin Ho, Alexandre Hoctin, Isabelle Hoffmann, Wei Han Hoh, Oscar Hoiting, Rebecca Holt, Jan Cato Holter, Juan Pablo Horcajada, Ikram Houas, Mabrouka Houderi, Catherine L. Hough, Stuart Houltham, Jimmy Ming-Yang Hsu, Jean-Sébastien Hulot, Abby Hurd, Iqbal Hussain, Aliae Mohamed Hussein, Mahmood Hussein, Fatima Ibrahim, Bashir Ibran, Samreen Ijaz, M. Arfan Ikram, Carlos Cañada Illana, Patrick Imbert, Muhammad Imran Ansari, Rana Imran Sikander, Hugo Inácio, Carmen Infante Dominguez, Yun Sii Ing, Mariachiara Ippolito, Vera Irawany, Sarah Isgett, Tiago Isidoro, Nadiah Ismail, Margaux Isnard, Mette Stausland Istre, Junji Itai, Daniel Ivulich, Danielle Jaafar, Salma Jaafoura, Hamza Jaber, Julien Jabot, Clare Jackson, Abubacarr Jagne, Stéphane Jaureguiberry, Denise Jaworsky, Florence Jego, Anilawati Mat Jelani, Synne Jenum, Ruth Jimbo-Sotomayor, Ong Yiaw Joe, Ruth Noemí Jorge García, Silje Bakken Jørgensen, Cédric Joseph, Mark Joseph, Swosti Joshi, Mercé Jourdain, Philippe Jouvet, Anna Jung, Hanna Jung, Dafsah Juzar, Ouifiya Kafif, Florentia Kaguelidou, Neerusha Kaisbain, Thavamany Kaleesvran, Sabina Kali, Karl Trygve Kalleberg, Smaragdi Kalomoiri, Muhammad Aisar Ayadi Kamaluddin, Armand Saloun Kamano, Zul Amali Che Kamaruddin, Nadiah Kamarudin, Kavita Kamineni, Darshana Hewa Kandamby, Kong Yeow Kang, Darakhshan Kanwal, Dyah Kanyawati, Mohamed Karghul, Pratap Karpayah, Todd Karsies, Daisuke Kasugai, Kevin Katz, Christy Kay, Lamees Kayyali, Seán Keating, Pulak Kedia, Andrea Kelly, Aoife Kelly, Claire Kelly, Niamh Kelly, Sadie Kelly, Yvelynne Kelly, Maeve Kelsey, Kalynn Kennon, Sommay Keomany, Maeve Kernan, Younes Kerroumi, Sharma Keshav, Shams Khail, Sarah Khaled, Imrana Khalid, Antoine Khalil, Irfan Khan, Quratul Ain Khan, Sushil Khanal, Abid Khatak, Krish Kherajani, Michelle E. Kho, Denisa Khoo, Ryan Khoo, Saye Khoo, Muhammad Nasir Khoso, Amin Khuwaja, Khor How Kiat, Yuri Kida, Peter Kiiza, Beathe Kiland Granerud, Anders Benjamin Kildal, Jae Burm Kim, Antoine Kimmoun, Detlef Kindgen-Milles, Nobuya Kitamura, Eyrun Floerecke Kjetland Kjetland, Paul Klenerman, Rob Klont, Gry Kloumann Bekken, Stephen R. Knight, Robin Kobbe, Paa Kobina Forson, Chamira Kodippily, Malte Kohns Vasconcelos, Sabin Koirala, Mamoru Komatsu, Franklina Korkor Abebrese, Volkan Korten, Stephanie Kouba, Mohamed Lamine Kourouma, Karifa Kourouma, Arsène Kpangon, Karolina Krawczyk, Ali Kredan, Vinothini Krishnan, Sudhir Krishnan, Oksana Kruglova, Anneli Krund, Pei Xuan Kuan, Ashok Kumar, Deepali Kumar, Ganesh Kumar, Mukesh Kumar, Dinesh Kuriakose, Ethan Kurtzman, Demetrios Kutsogiannis, Galyna Kutsyna, Ama Kwakyewaa Bedu-Addo, Sylvie Kwedi, Konstantinos Kyriakoulis, Marie Lachatre, Marie Lacoste, John G. Laffey, Nadhem Lafhej, Marie Lagrange, Fabrice Laine, Olivier Lairez, Sanjay Lakhey, Marc Lambert, François Lamontagne, Marie Langelot-Richard, Vincent Langlois, Eka Yudha Lantang, Marina Lanza, Cédric Laouénan, Samira Laribi, Delphine Lariviere, Stéphane Lasry, Sakshi Lath, Naveed Latif, Youssef Latifeh, Odile Launay, Didier Laureillard, Yoan Lavie-Badie, Andy Law, Cassie Lawrence, Teresa Lawrence, Minh Le, Clément Le Bihan, Cyril Le Bris, Georges Le Falher, Lucie Le Fevre, Quentin Le Hingrat, Marion Le Maréchal, Soizic Le Mestre, Gwenaël Le Moal, Vincent Le Moing, Hervé Le Nagard, Ema Leal, Marta Leal Santos, Biing Horng Lee, Heng Gee Lee, Su Hwan Lee, Jennifer Lee, Todd C. Lee, Yi Lin Lee, Gary Leeming, Bénédicte Lefebvre, Laurent Lefebvre, Benjamin Lefèvre, Sylvie LeGac, Merili-Helen Lehiste, Jean-Daniel Lelievre, François Lellouche, Adrien Lemaignen, Véronique Lemee, Anthony Lemeur, Gretchen Lemmink, Ha Sha Lene, Jenny Lennon, Rafael León, Marc Leone, Tanel Lepik, Quentin Lepiller, François-Xavier Lescure, Olivier Lesens, Mathieu Lesouhaitier, Amy Lester-Grant, Andrew Letizia, Sophie Letrou, Bruno Levy, Yves Levy, Claire Levy-Marchal, Katarzyna Lewandowska, Erwan L'Her, Gianluigi Li Bassi, Janet Liang, Ali Liaquat, Geoffrey Liegeon, Kah Chuan Lim, Wei Shen Lim, Chantre Lima, Bruno Lina, Lim Lina, Andreas Lind, Maja Katherine Lingad, Guillaume Lingas, Sylvie Lion-Daolio, Keibun Liu, Marine Livrozet, Patricia Lizotte, Antonio Loforte, Navy Lolong, Leong Chee Loon, Diogo Lopes, Dalia Lopez-Colon, Anthony L. Loschner, Paul Loubet, Bouchra Loufti, Guillame Louis, Silvia Lourenco, Lara Lovelace-Macon, Lee Lee Low, Marije Lowik, Jia Shyi Loy, Jean Christophe Lucet, Carlos M. Luna, Olguta Lungu, Miles Lunn, Liem Luong, Nestor Luque, Dominique Luton, Olavi Maasikas, Moïse Machado, Sara Machado, Gabriel Macheda, Mustafa Magzoub, Rafael Mahieu, Sophie Mahy, Ana Raquel Maia, Lars S. Maier, Oumou Maiga Ascofare, Mylène Maillet, Thomas Maitre, Nimisha Abdul Majeed, Maximilian Malfertheiner, Nadia Malik, Paddy Mallon, Fernando Maltez, Denis Malvy, Victoria Manda, Laurent Mandelbrot, Frank Manetta, Julie Mankikian, Edmund Manning, Aldric Manuel, Veronika Maráczi, Ceila Maria Sant′Ana Malaque, Flávio Marino, Samuel Markowicz, Ana Marques, Catherine Marquis, Laura Marsh, Brian Marsh, Megan Marshal, John Marshall, Celina Turchi Martelli, Dori-Ann Martin, Emily Martin, Guillaume Martin-Blondel, Alessandra Martinelli, F. Eduardo Martinez, Martin Martinot, Alejandro Martín-Quiros, Ana Martins, João Martins, Nuno Martins, Caroline Martins Rego, Gennaro Martucci, Olga Martynenko, Eva Miranda Marwali, Marsilla Marzukie, David Maslove, Sabina Mason, Sobia Masood, Fatma Masoud, Moise Massoma, Palmer Masumbe, Mohd Basri Mat Nor, Moshe Matan, Henrique Mateus Fernandes, Meghena Mathew, Christina Mathew, Mathieu Mattei, Laurence Maulin, Juergen May, Javier Maynar, Mayfong Mayxay, Thierry Mazzoni, Lisa Mc Sweeney, Colin McArthur, Naina McCann, Peter McCanny, Aine McCarthy, Anne McCarthy, Colin McCloskey, Rachael McConnochie, Sherry McDermott, Sarah E. McDonald, Aine McElroy, Samuel McElwee, Natalie McEvoy, Allison McGeer, Kenneth A. McLean, Paul McNally, Bairbre McNicholas, Edel Meaney, Cécile Mear-Passard, Maggie Mechlin, Nastia Medombou, Omar Mehkri, Ferruccio Mele, Luis Melo, Kashif Ali Memon, João João Mendes, Ogechukwu Menkiti, Kusum Menon, France Mentré, Alexander J. Mentzer, Emmanuelle Mercier, Noémie Mercier, Antoine Merckx, Mayka Mergeay-Fabre, Blake Mergler, António Mesquita, Roberta Meta, Osama Metwally, Agnès Meybeck, Dan Meyer, Alison M. Meynert, Vanina Meysonnier, Mehdi Mezidi, Céline Michelanglei, Isabelle Michelet, Efstathia Mihelis, Vladislav Mihnovit, Duha Milad Abdullah, Jennene Miller, Hugo Miranda-Maldonado, Nor Arisah Misnan, Nik Nur Eliza Mohamed, Nouralsabah Mohamed, Tahira Jamal Mohamed, Alaa Mohamed Ads, Ahmed Reda Mohamed Elsayed Abdelhalim, Libya Mohammed, Shrouk Fawze Mohammed Mostafa, Manahil Omer Abdelrahman Mohammedahmed, Omer Abdullah Mohammedelhassan, Asma Moin, Walaa Mokhtar, Elena Molinos, Brenda Molloy, Mary Mone, Agostinho Monteiro, Claudia Montes, Giorgia Montrucchio, Sarah Moore, Shona C. Moore, Lina Morales Cely, Marwa Morgom, Lucia Moro, Catherine Motherway, Ana Motos, Hugo Mouquet, Clara Mouton Perrot, Julien Moyet, Suleiman Haitham Mualla, Mohamed Muftah, Aisha Kalsoom Mufti, Ng Yong Muh, Mo'nes Muhaisen, Dzawani Muhamad, Jimmy Mullaert, Fredrik Müller, Karl Erik Müller, Daniel Munblit, Syed Muneeb Ali, Nadeem Munir, Laveena Munshi, Aisling Murphy, Patrick Murray, Marlène Murris, Srinivas Murthy, Himed Musaab, Alamin Mustafa, Mus'ab Mustafa, Dana Mustafa, Himasha Muvindi, Dimitra Melia Myrodia, Farah Nadia Mohd-Hanafiah, Behzad Nadjm, Dave Nagpal, Alex Nagrebetsky, Blanka Nagybányai-Nagy, Herwin Nanda Boudoin, Mangala Narasimhan, Nageswaran Narayanan, Prashant Nasa, Rashid Nasim Khan, Ahmad Nasrallah, Adel Gerges Nassif Metri, Alasdair Nazerali-Maitland, Nadège Neant, Holger Neb, Nikita Nekliudov, Matthew Nelder, Erni Nelwan, Raul Neto, Emily Neumann, Wing Yiu Ng, Pauline Yeung Ng, Anthony Nghi, Duc Nguyen, Orna Ni Choileain, Niamh Ni Leathlobhair, Nerissa Niba, Alistair D. Nichol, Prompak Nitayavardhana, Stephanie Nonas, Nurul Amani Mohd Noordin, Nurul Faten Izzati Norharizam, Anita North, Alessandra Notari, Mahdad Noursadeghi, Adam Nowinski, Saad Nseir, Leonard Numfor, Nurnaningsih Nurnaningsih, Dwi Utomo Nusantara, Elsa Nyamankolly, Anders Benteson Nygaard, Fionnuala O. Brien, Annmarie O. Callaghan, Annmarie O'Callaghan, Giovanna Occhipinti, Derbrenn OConnor, Max O'Donnell, Lawrence Ofori-Boadu, Tawnya Ogston, Takayuki Ogura, Tak-Hyuk Oh, Sophie O'Halloran, Katie O'Hearn, Sally-Ann Ohene, João Oliveira, Larissa Oliveira, Piero L. Olliaro, Cinderella Omar Rageh Elnaggar, Alsarrah Ali Mohammed Omer, Pierre Ondobo, David S.Y. Ong, Jee Yan Ong, Wilna Oosthuyzen, Anne Opavsky, Peter Openshaw, Saijad Orakzai, Claudia Milena Orozco-Chamorro, Jamel Ortoleva, Mohamed Osama Elsayed Soliman, Javier Osatnik, Linda O'Shea, Miriam O'Sullivan, Eman Othman, Siti Zubaidah Othman, Nadia Ouamara, Rachida Ouissa, Micheal Owusu, Ama Akyampomaa Owusu-Asare, Eric Oziol, Maïder Pagadoy, Justine Pages, Amanda Palacios, Massimo Palmarini, Giovanna Panarello, Hem Paneru, Lai Hui Pang, Mauro Panigada, Nathalie Pansu, Aurélie Papadopoulos, Rachael Parke, Melissa Parker, Jérémie Pasquier, Bruno Pastene, Fabian Patauner, Drashti Patel, Mohan Dass Pathmanathan, Luís Patrão, Patricia Patricio, Lisa Patterson, Rajyabardhan Pattnaik, Christelle Paul, Mical Paul, Jorge Paulos, William A. Paxton, Jean-François Payen, Sandra L. Peake, Kalaiarasu Peariasamy, Giles J. Peek, Florent Peelman, Nathan Peiffer-Smadja, Vincent Peigne, Mare Pejkovska, Paolo Pelosi, Ithan D. Peltan, Rui Pereira, Daniel Perez, Thomas Perpoint, Antonio Pesenti, Vincent Pestre, Lenka Petrou, Michele Petrovic, Ventzislava Petrov-Sanchez, Frank Olav Pettersen, Gilles Peytavin, Richard Odame Philips, Ooyanong Phonemixay, Soulichanya Phoutthavong, Michael Piagnerelli, Walter Picard, Olivier Picone, Maria de Piero, Djura Piersma, Carlos Pimentel, Raquel Pinto, Catarina Pires, Lionel Piroth, Ayodhia Pitaloka, Chiara Piubelli, Riinu Pius, Simone Piva, Laurent Plantier, Hon Shen Png, Julien Poissy, Ryadh Pokeerbux, Sergio Poli, Georgios Pollakis, Diane Ponscarme, Diego Bastos Porto, Andra-Maris Post, Douwe F. Postma, Pedro Povoa, Diana Póvoas, Jeff Powis, Sofia Prapa, Viladeth Praphasiri, Sébastien Preau, Christian Prebensen, Jean-Charles Preiser, Anton Prinssen, Gamage Dona Dilanthi Priyadarshani, Lucia Proença, Sravya Pudota, Bambang Pujo Semedi, Mathew Pulicken, Peter Puplampu, Gregory Purcell, Luisa Quesada, Vilmaris Quinones-Cardona, Else Quist-Paulsen, Mohammed Quraishi, Fadi Qutishat, Maia Rabaa, Christian Rabaud, Ebenezer Rabindrarajan, Aldo Rafael, Marie Rafiq, Abdelrahman Ragab, Mutia Rahardjani, Arslan Rahat Ullah, Ahmad Kashfi Haji Ab Rahman, Rozanah Abd Rahman, Fernando Rainieri, Giri Shan Rajahram, Pratheema Ramachandran, Nagarajan Ramakrishnan, José Ramalho, Ahmad Afiq Ramli, Blandine Rammaert, Grazielle Viana Ramos, Asim Rana, Rajavardhan Rangappa, Ritika Ranjan, Christophe Rapp, Aasiyah Rashan, Thalha Rashan, Ghulam Rasheed, Menaldi Rasmin, Indrek Rätsep, Cornelius Rau, Tharmini Ravi, Ali Raza, Andre Real, Stanislas Rebaudet, Sarah Redl, Brenda Reeve, Attaur Rehman, Muhammad Osama Rehman Khalid, Dag Henrik Reikvam, Renato Reis, Jonathan Remppis, Martine Remy, Hongru Ren, Hanna Renk, Anne-Sophie Resseguier, Matthieu Revest, Oleksa Rewa, Maria Ines Ribeiro, Antonia Ricchiuto, David Richardson, Denise Richardson, Laurent Richier, Siti Nurul Atikah Ahmad Ridzuan, Ana L. Rios, Asgar Rishu, Patrick Rispal, Karine Risso, Maria Angelica Rivera Nuñez, Chiara Robba, André Roberto, Stephanie Roberts, Charles Roberts, David L. Robertson, Olivier Robineau, Anna Roca, Ferran Roche-Campo, Paola Rodari, Simão Rodeia, Bernhard Roessler, Claire Roger, Pierre-Marie Roger, Roberto Roncon-Albuquerque, Jr., Mélanie Roriz, Manuel Rosa-Calatrava, Michael Rose, Dorothea Rosenberger, Andrea Rossanese, Matteo Rossetti, Patrick Rossignol, Carine Roy, Benoît Roze, Desy Rusmawatiningtyas, Clark D. Russell, Maeve Ryan, Steffi Ryckaert, Aleksander Rygh Holten, Isabela Saba, Sairah Sadaf, Musharaf Sadat, Valla Sahraei, Abdurraouf Said, Nadia Saidani, Pranya Sakiyalak, Fodé Bangaly Sako, Moamen Salah, Ali Alaa Salah Eldin Mohamed Abbas, Nawal Salahuddin, Leonardo Salazar, Jodat Saleem, Mohammed Saleh Alyasiri, Talat Ahmed Abu Salem, Gabriele Sales, Charlotte Salmon Gandonniere, Hélène Salvator, Dana Samardali, Shaden Samardali, Yehia Samir Shaaban Aly Orabi, Emely Sanchez, Olivier Sanchez, Kizy Sanchez de Oliveira, Angel Sanchez-Miralles, Vanessa Sancho-Shimizu, Gyan Sandhu, Zulfiqar Sandhu, Pierre-François Sandrine, Oana Săndulescu, Marlene Santos, Shirley Sarfo-Mensah, Bruno Sarmento Banheiro, Iam Claire E. Sarmiento, Benjamine Sarton, Ankana Satya, Sree Satyapriya, Rumaisah Satyawati, Egle Saviciute, Yen Tsen Saw, Justin Schaffer, Tjard Schermer, Arnaud Scherpereel, Marion Schneider, János Schnur, Stephan Schroll, Michael Schwameis, Gary Schwartz, Janet T. Scott, James Scott-Brown, Nicholas Sedillot, Tamara Seitz, Jaganathan Selvanayagam, Mageswari Selvarajoo, Malcolm G. Semple, Rasidah Bt Senian, Eric Senneville, Claudia Sepulveda, Filipa Sequeira, Tânia Sequeira, Ary Serpa Neto, Ellen Shadowitz, Syamin Asyraf Shahidan, Hamza Shahla, Laila Shalabi, Haitam Shames, Anuraj Shankar, Shaikh Sharjeel, Pratima Sharma, Catherine A. Shaw, Victoria Shaw, John Robert Sheenan, Dr. Rajesh Mohan Shetty, Rohan Shetty, Mohiuddin Shiekh, Nobuaki Shime, Keiki Shimizu, Sally Shrapnel, Shubha Kalyan Shrestha, Pramesh Sundar Shrestha, Hoi Ping Shum, Nassima Si Mohammed, Ng Yong Siang, Moses Siaw-Frimpong, Jeanne Sibiude, Bountoy Sibounheuang, Nidhal Siddig, Atif Siddiqui, Maqsood Ahmed Siddiqui, Louise Sigfrid, Fatoumata Sillah, Piret Sillaots, Catarina Silva, Maria Joao Silva, Rogério Silva, Benedict Sim Lim Heng, Wai Ching Sin, Dario Sinatti, Mahendra Singh, Punam Singh, Pompini Agustina Sitompul, Karisha Sivam, Vegard Skogen, Sue Smith, Benjamin Smood, Coilin Smyth, Morgane Snacken, Dominic So, Tze Vee Soh, Lene Bergendal Solberg, Joshua Solomon, Tom Solomon, Emily Somers, Agnès Sommet, Myung Jin Song, Rima Song, Tae Song, Jack Song Chia, Arne Søraas, Albert Sotto, Edouard Soum, Ana Chora Sousa, Marta Sousa, Maria Sousa Uva, Vicente Souza-Dantas, Mamadou Saliou Sow, Alexandra Sperry, Elisabetta Spinuzza, B. P. Sanka Ruwan Sri Darshana, Shiranee Sriskandan, Sarah Stabler, Thomas Staudinger, Stephanie-Susanne Stecher, Trude Steinsvik, Ymkje Stienstra, Birgitte Stiksrud, Eva Stolz, Amy Stone, Anca Streinu-Cercel, Adrian Streinu-Cercel, Geoff Strong, Ami Stuart, David Stuart, Richa Su, Decy Subekti, Gabriel Suen, Jacky Y. Suen, Prasanth Sukumar, Asfia Sultana, Charlotte Summers, Dubravka Supic, Deepashankari Suppiah, Magdalena Surovcová, Atie Suwarti, Andrey Svistunov, Sarah Syahrin, Augustina Sylverken, Konstantinos Syrigos, Jaques Sztajnbok, Konstanty Szuldrzynski, Shirin Tabrizi, Fabio S. Taccone, Lysa Tagherset, Shahdattul Mawarni Taib, Sara Taleb, Cheikh Talla, Jelmer Talsma, Renaud Tamisier, Maria Lawrensia Tampubolon, Kim Keat Tan, Yan Chyi Tan, Hiroyuki Tanaka, Taku Tanaka, Hayato Taniguchi, Huda Taqdees, Arshad Taqi, Coralie Tardivon, Yousef Tarek Kamal Mostafa, Ali Tarhabat, Pierre Tattevin, M Azhari Taufik, Hassan Tawfik, Tze Yuan Tee, João Teixeira, Sofia Tejada, Marie-Capucine Tellier, Sze Kye Teoh, Vanessa Teotonio, François Téoulé, Olivier Terrier, Nicolas Terzi, Hubert Tessier-Grenier, Adrian Tey, Alif Adlan Mohd Thabit, Anand Thakur, Zhang Duan Tham, Suvintheran Thangavelu, Elmi Theron, Vincent Thibault, Simon-Djamel Thiberville, Benoît Thill, Jananee Thirumanickam, Niamh Thompson, Shaun Thompson, Emma C. Thomson, David Thomson, Mathew Thorpe, Surain Raaj Thanga Thurai, Ryan S. Thwaites, Paul Tierney, Vadim Tieroshyn, Peter S. Timashev, Jean-François Timsit, Noémie Tissot, Fiona Toal, Jordan Zhien Yang Toh, Maria Toki, Kristian Tonby, Sia Loong Tonnii, Marta Torre, Antoni Torres, Margarida Torres, Rosario Maria Torres Santos-Olmo, Hernando Torres-Zevallos, Aboubacar Tounkara, Michael Towers, Fodé Amara Traoré, Tony Trapani, Cécile Tromeur, Ioannis Trontzas, Tiffany Trouillon, Jeanne Truong, Christelle Tual, Sarah Tubiana, Helen Tuite, Alexis F. Turgeon, Jean-Marie Turmel, Lance C.W. Turtle, Anders Tveita, Pawel Twardowski, Makoto Uchiyama, PG Ishara Udayanga, Andrew Udy, Roman Ullrich, Alberto Uribe, Asad Usman, Effua Usuf, Timothy M. Uyeki, Cristinava Vajdovics, Piero Valentini, Luís Val-Flores, Stijn Van de Velde, Marcel van den Berge, Machteld van der Feltz, Job van der Palen, Paul van der Valk, Nicky Van Der Vekens, Peter Van der Voort, Sylvie Van Der Werf, Laura van Gulik, Jarne Van Hattem, Carolien van Netten, Ilonka van Veen, Noémie Vanel, Henk Vanoverschelde, Michael Varrone, Shoban Raj Vasudayan, Charline Vauchy, Pavan Kumar Vecham, Shaminee Veeran, Aurélie Veislinger, Sebastian Vencken, Sara Ventura, Annelies Verbon, José Ernesto Vidal, César Vieira, Deepak Vijayan, Judit Villar, Pierre-Marc Villeneuve, Andrea Villoldo, Gayatri Vishwanathan, Benoit Visseaux, Hannah Visser, Chiara Vitiello, Manivanh Vongsouvath, Harald Vonkeman, Fanny Vuotto, Suhaila Abdul Wahab, Noor Hidayu Wahab, Nadirah Abdul Wahid, Marina Wainstein, Laura Walsh, Wan Fadzlina Wan Muhd Shukeri, Chih-Hsien Wang, Steve Webb, Katharina Weil, Tan Pei Wen, Hassi Wesam, Sanne Wesselius, T. Eoin West, Murray Wham, Bryan Whelan, Nicole White, Paul Henri Wicky, Aurélie Wiedemann, Surya Otto Wijaya, Keith Wille, Sue Willems, Bailey Williams, Patricia J. Williams, Virginie Williams, Jessica Wittman, Calvin Wong, Xin Ci Wong, Yew Sing Wong, Teck Fung Wong, Natalie Wright, Lim Saio Xian, Ioannis Xynogalas, Siti Rohani Binti Mohd Yakop, Masaki Yamazaki, Elizabeth Yarad, Yazdan Yazdanpanah, Nicholas Yee Liang Hing, Abdelrahman Yehia Mahmoud Abdelaal, Cécile Yelnik, Chian Hui Yeoh, Stephanie Yerkovich, Touxiong Yiaye, Toshiki Yokoyama, Hodane Yonis, Obada Yousif, Saptadi Yuliarto, Akram Zaaqoq, Marion Zabbe, Gustavo E. Zabert, Kai Zacharowski, Masliza Zahid, Maram Zahran, Nor Zaila Binti Zaidan, Maria Zambon, Miguel Zambrano, Alberto Zanella, Nurul Zaynah, Hiba Zayyad, Alexander Zoufaly, and David Zucman

Subjects
COVID-19, Non-respiratory symptoms, Respiratory symptoms, Risk factors, Mortality, Science (General), Q1-390, Social sciences (General), H1-99
Abstract

Background: COVID-19 is primarily known as a respiratory illness; however, many patients present to hospital without respiratory symptoms. The association between non-respiratory presentations of COVID-19 and outcomes remains unclear. We investigated risk factors and clinical outcomes in patients with no respiratory symptoms (NRS) and respiratory symptoms (RS) at hospital admission. Methods: This study describes clinical features, physiological parameters, and outcomes of hospitalised COVID-19 patients, stratified by the presence or absence of respiratory symptoms at hospital admission. RS patients had one or more of: cough, shortness of breath, sore throat, runny nose or wheezing; while NRS patients did not. Results: Of 178,640 patients in the study, 86.4 % presented with RS, while 13.6 % had NRS. NRS patients were older (median age: NRS: 74 vs RS: 65) and less likely to be admitted to the ICU (NRS: 36.7 % vs RS: 37.5 %). NRS patients had a higher crude in-hospital case-fatality ratio (NRS 41.1 % vs. RS 32.0 %), but a lower risk of death after adjusting for confounders (HR 0.88 [0.83–0.93]). Conclusion: Approximately one in seven COVID-19 patients presented at hospital admission without respiratory symptoms. These patients were older, had lower ICU admission rates, and had a lower risk of in-hospital mortality after adjusting for confounders.

Published
2024
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7. Omega-3 fatty acids enriched flaxseed oil effects on meat quality and fatty acid profile of broiler chi

Author

Sher ALI, Nouman ASIF, Muhammad HAYAT, Rana Muhammad BILAL, Kashif NAUMAN, Jamal NASIR, Bilal ASGHAR, and Iftikhar BADAR

Subjects
flaxseed oil, n-3 lc-pufa, meat quality, sensory attributes, broiler meat, Veterinary medicine, SF600-1100
Abstract

The study was planned to evaluate effect of adding flaxseed oil on meat quality, sensory attributes and fatty acids profile of broiler chicken meat. Further, optimization of supplementalflaxseed oil duration and level was also tested. A n=300 day-old broiler chicken (Ross-308) were procured from the hatchery and randomly divided into 5 treatments, T0 (control) T1 and T2 (3% and 4% flaxseed oil, 14-35 day), while T3 and T4 having (3% and 4% flaxseed oil, 21-35 day) groups respectively. Each treatment contained 6 replicates with 10 chicks per replicate. The T3 tested diet linearly raised n-3 (PUFA) contents. The n-6/n-3 ratio was also significantly lowered from 7.72 to 1.12%. Regardless of dietary flaxseed oil level, LC-PUFA contents were higher in the T2 group. Meat quality traits were not statistically affected while T1 exhibited a significantly increased meat tenderness value, but interestingly, all other sensory attributes remained statistically unaffected. An equivalent amount of n-3 LC-PUFA may be found in 3% dietary flaxseed oil for the last 21 days of rearing with optimized meat quality and sensory attributes. Healthy broiler meat enriched with n-3 fatty acids may be produced by dietary manipulation.

Published
2023
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8. Predictors of Preterm Neonatal Mortality in India and Pakistan: A Secondary Analysis of Data from PURPOSe Study

Author

Shiyam Sunder Tikmani MSc, Sarah Saleem FCPS, Afreen Sadia FCPS, Carla M. Bann PhD, Muhammad Hayat Bozdar FCPS, Jamal Raza MD, Sangappa M. Dhaded MD, Shivaprasad S. Goudar MD, Guruparasad Gowdar MD, Haleema Yasmin FCPS, Elizabeth M. McClure PhD, and Robert L. Goldenberg MD

Subjects
Pediatrics, RJ1-570
Abstract

Objective. To create a prediction model for preterm neonatal mortality. Methods. A secondary analysis was conducted using data from a prospective cohort study, the Project to Understand and Research Preterm Pregnancy Outcome South Asia. The Cox proportional hazard model was used and adjusted hazard ratios (AHR) with 95% confidence intervals (95% CI) were reported. Results. Overall, 3446 preterm neonates were included. The mean age of preterm neonates was 0.65 (1.25) hours and 52% were female. The preterm neonatal mortality rate was 23.3%. The maternal factors predicting preterm neonatal death was any antepartum hemorrhage, AHR 1.99 (1.60-2.47), while neonatal predictors were preterm who received positive pressure ventilation AHR 1.30 (1.08-1.57), temperature

Published
2024
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9. Pattern, frequency and factors associated with inappropriate high dosing in chronic kidney disease patients at a tertiary care hospital in Pakistan

Author

Muhammad Hayat, Nafees Ahmad, Syed Liaquat Ali Khan, Syed Mohkumuddin, Wajeeha Siddique, Amjad Khan, and Muhammad Atif

Subjects
Age, antibiotics, antidiabetics, antihypertensives, Cardiovascular diseases, Chronic renal disease, Diabetes mellitus, Diseases of the genitourinary system. Urology, RC870-923
Abstract

Abstract Background Patients with chronic kidney diseases (CKD) are susceptible to the toxic drug effects if given unadjusted doses. Although Pakistan harbors a high burden of CKD patients, there is limited information available on the frequency, pattern and factors associated with unadjusted drug doses among CKD patients. Methods This cross-sectional study conducted at Sandeman Provincial Hospital, Quetta included 303 non-dialysis ambulatory CKD patients (glomerular filtration rate 60 years (OR = 9.49), hypertension (OR = 2.68), diabetes mellitus (OR = 3.47) and cardiovascular diseases (OR = 2.82) had statistically significant association (p-value

Published
2023
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10. Identification of Prospective Ebola Virus VP35 and VP40 Protein Inhibitors from Myxobacterial Natural Products

Author

Muhammad Hayat, Tian Gao, Ying Cao, Muhammad Rafiq, Li Zhuo, and Yue-Zhong Li

Subjects
Ebola virus, VP35 and VP40 proteins, myxobacterial natural products, molecular docking, molecular dynamic simulation, Microbiology, QR1-502
Abstract

The Ebola virus (EBOV) is a lethal pathogen causing hemorrhagic fever syndrome which remains a global health challenge. In the EBOV, two multifunctional proteins, VP35 and VP40, have significant roles in replication, virion assembly, and budding from the cell and have been identified as druggable targets. In this study, we employed in silico methods comprising molecular docking, molecular dynamic simulations, and pharmacological properties to identify prospective drugs for inhibiting VP35 and VP40 proteins from the myxobacterial bioactive natural product repertoire. Cystobactamid 934-2, Cystobactamid 919-1, and Cittilin A bound firmly to VP35. Meanwhile, 2-Hydroxysorangiadenosine, Enhypyrazinone B, and Sorangiadenosine showed strong binding to the matrix protein VP40. Molecular dynamic simulations revealed that, among these compounds, Cystobactamid 919-1 and 2-Hydroxysorangiadenosine had stable interactions with their respective targets. Similarly, molecular mechanics Poisson–Boltzmann surface area (MMPBSA) calculations indicated close-fitting receptor binding with VP35 or VP40. These two compounds also exhibited good pharmacological properties. In conclusion, we identified Cystobactamid 919-1 and 2-Hydroxysorangiadenosine as potential ligands for EBOV that target VP35 and VP40 proteins. These findings signify an essential step in vitro and in vivo to validate their potential for EBOV inhibition.

Published
2024
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11. Study of modified biomass of Gossypium hirsutum as heavy metal biosorbent

Author

Zeeshan Ali, Muhammad Sajid, Nadeem Raza, Younas Sohail, Muhammad Hayat, Suryyia Manzoor, Nasir Shakeel, Komal Aziz Gill, Ahmad A. Ifseisi, and Mohd Zahid Ansari

Subjects
Gossypium hirsutum, Heavy metal ions removal, Adsorption isotherms, Biomass modifications, Kinetics, Environmental samples, Chemistry, QD1-999
Abstract

The presence of heavy metals in aqueous media can cause serious threats to living organisms. Consequently, for the efficient and economic removal of heavy metals from water, a wide range of biomass as biosorbents has been investigated. The present study was designed to deploy Gossypium hirsutum stem powder as a biosorbent for efficient removal of toxic heavy metals including Pb2+, Cu2+, Zn2+ and Ni2+ ions from aqueous media. The biomass was modified through acid and base treatment prior to its deployment as biosorbent. Different instrumental techniques such as FTIR, SEM and TGA were used to analyze the structural, morphological, and thermal characteristics of biosorbent. AAS, and UV spectrophotometer were used to quantify the metal ions in solutions. Nonlinear models of Langmuir and Freundlich isotherms was explored for practical use in real sample analysis, and adsorption parameters were optimized systematically. The adsorption isotherms followed the non-linear Langmuir model, which best fit four heavy metals with an R2 value (0.99) in both acidic and base-modified biomass. The base treated biomass showed relatively higher maximum uptake capacity for the investigated heavy metals (Pb2+ 121.24, Cu2+ 117.09, Zn2+ 130.65, and Ni2+ 111.09 mg g−1) than that of acid treated biomass. Thermogravimetric analysis revealed the degradation pattern of designed adsorbent. Fourier transform infrared spectroscopy confirmed the presence of OH and Cl groups which were added during pretreatment. Scanning electron microscopy showed that the modified material has rough surface area which can contribute in enhancing the adsorption of heavy metals. The regeneration studies of modified biosorbent using 0.1 M HNO3 solution demonstrated that the biosorbent can be effectively utilized for further five biosorption cycles without significant loss in its adsorption capability. The findings of the study revealed that acid and base modified Gossypium hirsutum stem could be efficiently utilized as a biosorbent for the removal of heavy metals in water at pH 5.5 with an adsorbent dose of 0.5 g and equilibrium time of 35 min.

Published
2023
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12. The role of DMSO and MSM in treatment of tendinopathies affection in equine: A comparative study

Author

Hamid Akbar, Fiaz Ahmad, Muhammad Hayat, Muhammad Khan, Muhammad Tipu, Muhammad Sajjad, Hafiz Ahmad, and Fawad Khalil

Subjects
sdft, horses, dmso, msm, ultrasonography, Veterinary medicine, SF600-1100
Abstract

Superficial digital flexor tendon (SDFT) injury is a main cause of lameness in polo and racehorses inciting long-term lameness and recovery. This study aimed to compare the efficacy of topical dimethyl sulfoxide (DMSO) and Methylsulfonylmethane (MSM) on bowed tendons in horses. Ten client-owned injured horses, aged between 5-15 years with an average age of 8.5 years and weighing approximately 400-500 kg, suffering from chronic tendinitis were selected and allocated into two groups: group A (DMSO) and group B (MSM). The group A animals (n=5) were treated with 60 mL of topical 90% DMSO aqueous solution, while Group B animals (n=5) received 60 mL of topical 90% MSM aqueous solution on the bowed tendon at days 0, 7, 14, 21, 28, 35, and day 42. Clinical examinations were performed to evaluate the severity of pain and lameness grade. Ultrasound scans of the superficial digital flexor tendon were taken at days 0, 21, and day 42. Images were placed in numerical form, and the fiber alignment score of the fibers (FS) and the echogenicity score (ES) of the superficial digital flexor tendon at the maximum injury zone (MIZ) were recorded. Results showed that pain reduction and lameness significantly (P0.05) however, it was significantly declined in group A at 42d than 0d (P

Published
2022
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13. Interannual variation in evapotranspiration in an urban forest reserve with respect to drought

Author

Ruizhi Yang, Peng Liu, Yun Tian, Jingyong Ma, Yujie Bai, Cheng Li, Songyu Huang, Yanmei Mu, Muhammad Hayat, Sundas Iqbal, Haiqun Yu, Feng Zhang, and Hong Ma

Subjects
drought, evapotranspiration, interannual variability, precipitation, urban forests, Forestry, SD1-669.5, Environmental sciences, GE1-350
Abstract

IntroductionA warming global climate is expected to perturb the hydrological cycle, resulting in deviations in both frequency and duration of drought and thus being hypothesized to lead to interannual variation in evapotranspiration (ET). Interannual variation in ET in urban forest ecosystems in response to drought remains poorly understood.MethodsHere, ET in an urban forest reserve in the megalopolis of Beijing was investigated using eddy-covariance measurements collected over six consecutive years (2012–2017).ResultsThe mean annual cumulative ET was 462 ± 83mm (±first standard deviation), with a coefficient of variation of 18%. Interannual variation in both annual and monthly ET was shown to be largely controlled by canopy conductance (gs), affected by environmental factors. The main factors affecting interannual variation in monthly ET varied seasonally, namely, soil volumetric water content (VWC) and normalized difference vegetation index (NDVI) in spring, precipitation and soil temperature in summer, and VWC and net radiation (Rn) in autumn. Interannual variation in annual ET was driven largely by spring and mid-summer droughts induced by insufficient precipitation during the non-growing and mid-growing seasons, respectively. Spring drought reduced annual ET by restricting leafing out, shortening growing season length (GSL), and reducing the normalized difference vegetation index (NDVI). The summer drought reduced annual ET by reducing stomatal conductance.Discussion and conclusionResults from this study point to the importance of precipitation timing and volume and the soil moisture carry-over effect in controlling interannual variation in ecosystem ET. Irrigation during the early spring and mid-summer is viewed as a practical management measure for sustaining growth and better ecosystem services in urban forests in Northern China.

Published
2023
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14. Hypertriglyceridemia induced pancreatitis management – a case report

Author

Aisha Kulsoom Mufti, Naqeeb Ullah, Muhammad Hayat, and Muhammad Aimal Khan

Subjects
Hypertriglyceridemia induced Acute pancreatitis (HTAP), Lipoprotein lipase (LPL), Triglycerides (TG), Deep vein thrombosis (DVT), Systemic inflammatory response syndrome (SIRS), Hypertriglyceridemia (HTG), Medicine
Abstract

Acute pancreatitis results in high morbidity and mortality. Gallstones and alcoholism are considered leading causes of acute pancreatitis. However, increasing prevalence of obesity, diabetes and lifestyle choices has resulted in Hypertriglyceridemia induced pancreatitis (HTAP) becoming more common. HTAP is said to be more severe than other causes. The treatment options available vary including intravenous (IV) insulin, heparin, plasma exchange, fibrates, niacin, omega three fatty acids and dietary restrictions. This is a case report of a patient presenting with HTAP and the dilemma treating physicians faced in trying to balance the need for urgent treatment with invasiveness of procedure and paucity of evidence. Keywords: Hypertriglyceridemia induced Acute pancreatitis (HTAP), Lipoprotein lipase (LPL), Triglycerides (TG). Deep vein thrombosis (DVT), Systemic inflammatory response syndrome (SIRS), Hypertriglyceridemia (HTG), Infusions, Intravenous (IV).

Published
2023
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16. Punden Mbah Onggo Dongso: Tata Kelakuan dalam Legitimasi The Beyond (Studi di Dusun Tlogorejo, Desa Bumiaji, Kecamatan Bumiaji, Kota Batu)

Author

muhammad muhammad hayat

Subjects
Social Sciences
Abstract

Abstract Key words: Behavior, Legitimacy, The Beyond            Villagers Culture is inseparable with their vertical relation to nature. Nature is understood as a sign of caring, protecting and blessing. That concept places nature as the beyond. In the beyond, nature is placed as “thing†which has legitimacy. This phenomenon also happens in Tlogorejo District, Bumiaji Village, Bumiaji Regency Batu City. One of “thing†which is considered as the beyond is Punden Mbah Onggo Dốngso. Punden becomes a place where villagers go to ask for permission if they will hold or certain event such as wedding, khitan or other villagers events. It happens that the sign of nature has a lofty position as a sacred one or the beyond. This statement reflects the truly high degree of respect.            The beyond refers to the unseen reality as the basic power which can give a sign of protection on welfare for society when that place has been understood as the way society care, keep and perform contemplation ritual. Finally the elaboration of the three concepts has encouraged the society to always remember and want to know about the good power of Punden Mbah Onggo Dongso. Therefore the society continuously consider Punden Mbah Onggo Dongso as a place to consult or ask permission before they hold whatever events they want to have.               This research uses qualitative approach with deep analysis through verstehen method from Max Weber. The analysis is done using cyclical method from Miles and Huberman. The result shows that Punden Mbah Onggo Dongso is a from òf celebrating the presence of subject. It is a process of firming the legitimacy and behavior of the collective society. And the conclusion is Punden Mbah Onggo Dongso has become a way of society in appreciating the pagan in their daily behavior norms.      Â

Published
2023
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18. Detection of carbapenemases bla OXA48-bla KPC-bla NDM-bla VIM and extended-spectrum-β-lactamase bla OXA1-bla SHV-bla TEM genes in Gram-negative bacterial isolates from ICU burns patients

Author

Muhammad Hayat Haider, Timothy D. McHugh, Kerry Roulston, Liã Bárbara Arruda, Zahra Sadouki, and Saba Riaz

Subjects
Burns, Carbapenemases, Enterobacteriaceae, ESBLs, bla OXA48, Pseudomonas aeruginosa, Therapeutics. Pharmacology, RM1-950, Infectious and parasitic diseases, RC109-216, Microbiology, QR1-502
Abstract

Abstract Background and objectives Burn patients are highly susceptible to invasion by multidrug-resistant Gram-negative bacteria (MDR-GNB) through post-burn damage. The prevalence of MDR-GNB isolated from burns patients has increased dramatically in the last decade, representing a serious risk to patients admitted to burns units worldwide. The challenges of managing infected burns patients are exacerbated in poor resource settings. This study was designed to develop a pathway for the rapid diagnosis of multidrug-resistant (MDR) Gram-negative infections and identify the bacterial genes including bla OXA1, bla TEM, and bla SHV encoding ESBLs and bla OXA48, bla KPC, bla NDM, and bla VIM encoding carbapenemases from the patient of post burns infection. Methods Clinical isolates were collected (August 2017 to August 2018) from Intensive care unit (ICU) of Burn Centre. Antibiotic susceptibility testing and phenotypic detection of ESBLs and carbapenemases was performed by disk diffusion, double disk synergy test (DDST), combination disk test (CDT), and Imipenem + EDTA combined disk test (IMP + EDTA CDT). Polymerase chain reaction (PCR) detection was performed for ESBLs bla OXA1-bla SHV-bla TEM and carbapenemases genes bla OXA48-bla KPC-bla NDM-bla VIM Results In total, of 170 Gram-negative isolates, 104 (61.2%) were confirmed as multidrug-resistant (MDR); Pseudomonas aeruginosa was found to be the most prevalent 43/104 (41.4%), followed by Klebsiella pneumoniae 17/104 (16.4%), Acinetobacter baumannii12/104 (11.5%), and 6/104 Proteus mirabilis (5.8%). All isolates (100%) were resistant to cefotaxime and ceftazidime, while the meropenem resistance was 58.7%. ESBL and carbapenemase genotypes were found to be associated with higher MAR index (0.65–0.88) and MIC (> 32 µg/ml) values P. aeruginosa was the major ESBL and carbapenemase producer as determined by phenotypic testing and PCR. bla TEM positive isolates among ESBLs producers were predominant 81.8% (27/33), followed by 27.3% bla OXA1 and bla SHV, respectively. bla VIM positive isolates among carbapenemase producers were predominant 47.7% (21/44), followed by 27.3% bla KPC, 20.5% bla OXA48, and 11.4% bla NDM positive isolates. Conclusions The predominant organism causing burn infections was ESBL and carbapenemase-producing Pseudomonas aeruginosa. There are only limited effective antibiotics against such strains. bla VIM and bla TEM individually and in co-existence with bla KPC, bla OXA48, bla SHV, and bla OXA1 confer antimicrobial resistance in burns patients. Rapid detection of ESBL and carbapenemase genes will inform treatment strategies improving the outcome for post-burn patients in ICU.

Published
2022
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19. COVID-19 stressors and health behaviors: A multilevel longitudinal study across 86 countries

Author

Keng, Shian-Ling, Stanton, Michael V., Haskins, LeeAnn B., Almenara, Carlos A., Ickovics, Jeannette, Jones, Antwan, Grigsby-Toussaint, Diana, Agostini, Maximilian, Bélanger, Jocelyn J., Gützkow, Ben, Kreienkamp, Jannis, Lemay, Edward P., Jr., vanDellen, Michelle R., Abakoumkin, Georgios, Abdul Khaiyom, Jamilah Hanum, Ahmedi, Vjollca, Akkas, Handan, Atta, Mohsin, Bagci, Sabahat Cigdem, Basel, Sima, Berisha Kida, Edona, Bernardo, Allan B.I., Buttrick, Nicholas R., Chobthamkit, Phatthanakit, Choi, Hoon–Seok, Cristea, Mioara, Csaba, Sára, Damnjanovic, Kaja, Danyliuk, Ivan, Dash, Arobindu, Di Santo, Daniela, Douglas, Karen M., Enea, Violeta, Faller, Daiane G., Fitzsimons, Gavan, Gheorghiu, Alexandra, Gómez, Ángel, Hamaidia, Ali, Han, Qing, Helmy, Mai, Hudiyana, Joevarian, Jeronimus, Bertus F., Jiang, Ding–Yu, Jovanović, Veljko, Kamenov, Željka, Kende, Anna, Kieu, Tra Thi Thanh, Koc, Yasin, Kovyazina, Kamila, Kozytska, Inna, Krause, Joshua, Kruglanski, Arie W., Kurapov, Anton, Kutlaca, Maja, Lantos, Nóra Anna, Lesmana, Cokorda Bagus Jaya, Louis, Winnifred R., Lueders, Adrian, Maj, Marta, Malik, Najma Iqbal, Martinez, Anton, McCabe, Kira O., Mehulić, Jasmina, Milla, Mirra Noor, Mohammed, Idris, Molinario, Erica, Moyano, Manuel, Muhammad, Hayat, Mula, Silvana, Muluk, Hamdi, Myroniuk, Solomiia, Najafi, Reza, Nisa, Claudia F., Nyúl, Boglárka, O'Keefe, Paul A., Osuna, Jose Javier Olivas, Osin, Evgeny N., Park, Joonha, Pica, Gennaro, Pierro, Antonio, Rees, Jonas, Reitsema, Anne Margit, Resta, Elena, Rullo, Marika, Ryan, Michelle K., Samekin, Adil, Santtila, Pekka, Sasin, Edyta M., Schumpe, Birga M., Selim, Heyla A., Stroebe, Wolfgang, Sultana, Samiah, Sutton, Robbie M., Tseliou, Eleftheria, Utsugi, Akira, van Breen, Jolien Anne, Van Lissa, Caspar J., Van Veen, Kees, Vázquez, Alexandra, Wollast, Robin, Yeung, Victoria Wai–lan, Zand, Somayeh, Žeželj, Iris Lav, Zheng, Bang, Zick, Andreas, Zúñiga, Claudia, and Leander, N. Pontus

Published
2022
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20. Using machine learning to identify important predictors of COVID-19 infection prevention behaviors during the early phase of the pandemic

Author

Van Lissa, Caspar J., Stroebe, Wolfgang, vanDellen, Michelle R., Leander, N. Pontus, Agostini, Maximilian, Draws, Tim, Grygoryshyn, Andrii, Gützgow, Ben, Kreienkamp, Jannis, Vetter, Clara S., Abakoumkin, Georgios, Abdul Khaiyom, Jamilah Hanum, Ahmedi, Vjolica, Akkas, Handan, Almenara, Carlos A., Atta, Mohsin, Bagci, Sabahat Cigdem, Basel, Sima, Kida, Edona Berisha, Bernardo, Allan B.I., Buttrick, Nicholas R., Chobthamkit, Phatthanakit, Choi, Hoon-Seok, Cristea, Mioara, Csaba, Sára, Damnjanović, Kaja, Danyliuk, Ivan, Dash, Arobindu, Di Santo, Daniela, Douglas, Karen M., Enea, Violeta, Faller, Daiane Gracieli, Fitzsimons, Gavan J., Gheorghiu, Alexandra, Gómez, Ángel, Hamaidia, Ali, Han, Qing, Helmy, Mai, Hudiyana, Joevarian, Jeronimus, Bertus F., Jiang, Ding-Yu, Jovanović, Veljko, Kamenov, Željka, Kende, Anna, Keng, Shian-Ling, Thanh Kieu, Tra Thi, Koc, Yasin, Kovyazina, Kamila, Kozytska, Inna, Krause, Joshua, Kruglanksi, Arie W., Kurapov, Anton, Kutlaca, Maja, Lantos, Nóra Anna, Lemay, Edward P., Jr., Jaya Lesmana, Cokorda Bagus, Louis, Winnifred R., Lueders, Adrian, Malik, Najma Iqbal, Martinez, Anton P., McCabe, Kira O., Mehulić, Jasmina, Milla, Mirra Noor, Mohammed, Idris, Molinario, Erica, Moyano, Manuel, Muhammad, Hayat, Mula, Silvana, Muluk, Hamdi, Myroniuk, Solomiia, Najafi, Reza, Nisa, Claudia F., Nyúl, Boglárka, O’Keefe, Paul A., Olivas Osuna, Jose Javier, Osin, Evgeny N., Park, Joonha, Pica, Gennaro, Pierro, Antonio, Rees, Jonas H., Reitsema, Anne Margit, Resta, Elena, Rullo, Marika, Ryan, Michelle K., Samekin, Adil, Santtila, Pekka, Sasin, Edyta M., Schumpe, Birga M., Selim, Heyla A., Stanton, Michael Vicente, Sultana, Samiah, Sutton, Robbie M., Tseliou, Eleftheria, Utsugi, Akira, Anne van Breen, Jolien, Van Veen, Kees, Vázquez, Alexandra, Wollast, Robin, Wai-Lan Yeung, Victoria, Zand, Somayeh, Žeželj, Iris Lav, Zheng, Bang, Zick, Andreas, Zúñiga, Claudia, and Bélanger, Jocelyn J.

Published
2022
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21. Challenges and Approaches of Culturing the Unculturable Archaea

Author

Muhammad Rafiq, Noor Hassan, Maliha Rehman, Muhammad Hayat, Gullasht Nadeem, Farwa Hassan, Naveed Iqbal, Hazrat Ali, Sahib Zada, Yingqian Kang, Wasim Sajjad, and Muhsin Jamal

Subjects
archaeal cultivation, archaeal diversity, culturing media, culturing methods, Biology (General), QH301-705.5
Abstract

Since Carl Woese’s discovery of archaea as a third domain of life, numerous archaeal species have been discovered, yet archaeal diversity is poorly characterized. Culturing archaea is complicated, but several queries about archaeal cell biology, evolution, physiology, and diversity need to be solved by culturing and culture-dependent techniques. Increasing interest in demand for innovative culturing methods has led to various technological and methodological advances. The current review explains frequent hurdles hindering uncultured archaea isolation and discusses features for more archaeal cultivation. This review also discusses successful strategies and available media for archaeal culturing, which might be helpful for future culturing practices.

Published
2023
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22. Concern with COVID-19 pandemic threat and attitudes towards immigrants: The mediating effect of the desire for tightness

Author

Mula, Silvana, Di Santo, Daniela, Resta, Elena, Bakhtiari, Farin, Baldner, Conrad, Molinario, Erica, Pierro, Antonio, Gelfand, Michele J., Denison, Emmy, Agostini, Maximilian, Bélanger, Jocelyn J., Gützkow, Ben, Kreienkamp, Jannis, Abakoumkin, Georgios, Abdul Khaiyom, Jamilah Hanum, Ahmedi, Vjollca, Akkas, Handan, Almenara, Carlos A., Atta, Mohsin, Bagci, Sabahat Cigdem, Basel, Sima, Kida, Edona Berisha, Bernardo, Allan B.I., Buttrick, Nicholas R., Chobthamkit, Phatthanakit, Choi, Hoon-Seok, Cristea, Mioara, Csaba, Sára, Damnjanovic, Kaja, Danyliuk, Ivan, Dash, Arobindu, Douglas, Karen M., Enea, Violeta, Faller, Daiane Gracieli, Fitzsimons, Gavan J., Gheorghiu, Alexandra, Gómez, Ángel, Hamaidia, Ali, Han, Qing, Helmy, Mai, Hudiyana, Joevarian, Jeronimus, Bertus F., Jiang, Ding-Yu, Jovanović, Veljko, Kamenov, Željka, Kende, Anna, Keng, Shian-Ling, Kieu, Tra Thi Thanh, Koc, Yasin, Kovyazina, Kamila, Kozytska, Inna, Krause, Joshua, Kruglanski, Arie W., Kurapov, Anton, Kutlaca, Maja, Lantos, Nóra Anna, Lemay, Edward P., Jr, Lesmana, Cokorda Bagus Jaya, Louis, Winnifred R., Lueders, Adrian, Malik, Najma Iqbal, Martinez, Anton, McCabe, Kira O., Mehulić, Jasmina, Milla, Mirra Noor, Mohammed, Idris, Moyano, Manuel, Muhammad, Hayat, Muluk, Hamdi, Myroniuk, Solomiia, Najafi, Reza, Nisa, Claudia F., Nyúl, Boglárka, O'Keefe, Paul A., Olivas Osuna, Jose Javier, Osin, Evgeny N., Park, Joonha, Pica, Gennaro, Rees, Jonas H., Reitsema, Anne Margit, Rullo, Marika, Ryan, Michelle K., Samekin, Adil, Santtila, Pekka, Sasin, Edyta, Schumpe, Birga Mareen, Selim, Heyla A., Stanton, Michael Vicente, Stroebe, Wolfgang, Sultana, Samiah, Sutton, Robbie M., Tseliou, Eleftheria, Utsugi, Akira, van Breen, Jolien Anne, van Lissa, Caspar J., Van Veen, Kees, vanDellen, Michelle R., Vázquez, Alexandra, Wollast, Robin, Yeung, Victoria Wai-lan, Zand, Somayeh, Žeželj, Iris Lav, Zheng, Bang, Zick, Andreas, Zúñiga, Claudia, and Leander, N. Pontus

Published
2022
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23. Frequency, types and predictors of drug therapy problems among non-dialysis chronic kidney disease patients at a tertiary care hospital in Pakistan.

Author

Muhammad Hayat, Nafees Ahmad, Syed Mohkumuddin, Syed Liaquat Ali Khan, Amer Hayat Khan, Noman Ul Haq, Naheed Haque, and Amjad Khan

Subjects
Medicine, Science
Abstract

BackgroundDrug therapy problems (DTPs) are common among patients suffering from chronic kidney disease (CKD). However, there is a lack of information about DTPs and its predictors among CKD patients from Pakistan.ObjectivesTo evaluate the frequency, type and predictors of various types of DTPs among CKD patients at a tertiary-care hospital in Pakistan.MethodologyThis was a cross-sectional study carried out at Sandeman Provincial Hospital, Quetta between 1-11-2020 and 31-1-2021. It included 303 non-dialysis ambulatory patients of CKD-stage 3 and above. Cipolle et al., criterion was used for classifying the DTPs and a clinician at the study site checked the identified DTPs for accuracy. Data were analyzed by SPSS 23. Multivariate analysis was conducted to find the predictors of individual types of DTPs. A p-value ResultsThe patients received a total of 2265 drugs with a median of eight drugs per patient (range: 3-15 drugs). A total of 576 DTPs were identified among 86.1% patients with a median of two DTPs (interquartile range 1-3) per patient. Dosage too high (53.5%) was the most common DTP followed by adverse drug reactions (ADRs) (50.5%) and need of additional drug therapy (37.6%). In multivariate analysis, patients' age of >40 years emerged as a predictor of unnecessary drug therapy and dosage too high. The odds of needing a different drug product was significantly high in patients with cardiovascular diseases (CVD) and diabetes mellitus (DM). The dosage too low had significant association with CVD. The risk of ADRs was significantly high in elderly patients (>60 years) and those with CVD. The presence of hypertension, DM and CKD stage-5 emerged as predictors of dosage too high.ConclusionThis study revealed a high prevalence of DTPs among CKD patients. Targeted interventions in high risk patients may reduce the frequency of DTPs at the study site.

Published
2023
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26. Predictors of adherence to public health behaviors for fighting COVID-19 derived from longitudinal data

Author

Schumpe, Birga M., Van Lissa, Caspar J., Bélanger, Jocelyn J., Ruggeri, Kai, Mierau, Jochen, Nisa, Claudia F., Molinario, Erica, Gelfand, Michele J., Stroebe, Wolfgang, Agostini, Maximilian, Gützkow, Ben, Jeronimus, Bertus F., Kreienkamp, Jannis, Kutlaca, Maja, Lemay, Jr, Edward P., Reitsema, Anne Margit, vanDellen, Michelle R., Abakoumkin, Georgios, Abdul Khaiyom, Jamilah Hanum, Ahmedi, Vjollca, Akkas, Handan, Almenara, Carlos A., Atta, Mohsin, Bagci, Sabahat Cigdem, Basel, Sima, Berisha Kida, Edona, Bernardo, Allan B. I., Buttrick, Nicholas R., Chobthamkit, Phatthanakit, Choi, Hoon-Seok, Cristea, Mioara, Csaba, Sara, Damnjanović, Kaja, Danyliuk, Ivan, Dash, Arobindu, Di Santo, Daniela, Douglas, Karen M., Enea, Violeta, Faller, Daiane, Fitzsimons, Gavan J., Gheorghiu, Alexandra, Gómez, Ángel, Hamaidia, Ali, Han, Qing, Helmy, Mai, Hudiyana, Joevarian, Jiang, Ding-Yu, Jovanović, Veljko, Kamenov, Zeljka, Kende, Anna, Keng, Shian-Ling, Kieu, Tra Thi Thanh, Koc, Yasin, Kovyazina, Kamila, Kozytska, Inna, Krause, Joshua, Kruglanski, Arie W., Kurapov, Anton, Lantos, Nóra Anna, Lesmana, Cokorda Bagus J., Louis, Winnifred R., Lueders, Adrian, Malik, Najma Iqbal, Martinez, Anton P., McCabe, Kira O., Mehulić, Jasmina, Milla, Mirra Noor, Mohammed, Idris, Moyano, Manuel, Muhammad, Hayat, Mula, Silvana, Muluk, Hamdi, Myroniuk, Solomiia, Najafi, Reza, Nyúl, Boglárka, O’Keefe, Paul A., Olivas Osuna, Jose Javier, Osin, Evgeny N., Park, Joonha, Pica, Gennaro, Pierro, Antonio, Rees, Jonas H., Resta, Elena, Rullo, Marika, Ryan, Michelle K., Samekin, Adil, Santtila, Pekka, Sasin, Edyta, Selim, Heyla A., Stanton, Michael Vicente, Sultana, Samiah, Sutton, Robbie M., Tseliou, Eleftheria, Utsugi, Akira, van Breen, Jolien A., Van Veen, Kees, Vázquez, Alexandra, Wollast, Robin, Yeung, Victoria Wai-Lan, Zand, Somayeh, Žeželj, Iris Lav, Zheng, Bang, Zick, Andreas, Zúñiga, Claudia, and Leander, N. Pontus

Published
2022
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27. Modeling Mechanical Properties of Aluminum Composite Produced Using Stir Casting Method

Author

Jokhio, Muhammad Hayat, Panhwer, Muhammad Ibrahim, and Unar, Mukhtiar Ali

Subjects
Condensed Matter - Materials Science
Abstract

ANN (Artificial Neural Networks) modeling methodology was adopted for predicting mechanical properties of aluminum cast composite materials. For this purpose aluminum alloy were developed using conventional foundry method. The composite materials have complex nature which posses the nonlinear relationship among heat treatment, processing parameters, and composition and affects their mechanical properties. These nonlinear relation ships with properties can more efficiently be modeled by ANNs. Neural networks modeling needs sufficient data base consisting of mechanical properties, chemical composition and processing parameters. Such data base is not available for modeling. Therefore, a large range of experimental work was carried out for the development of aluminum composite materials. Alloys containing Cu, Mg and Zn as matrix were reinforced with 1- 15% Al2O3 particles using stir casting method. Alloys composites were cast in a metal mold. More than eighty standard samples were prepared for tensile tests. Sixty samples were given solution treatments at 580oC for half an hour and tempered at 120oC for 24 hours. The samples were characterized to investigate mechanical properties using Scanning Electron Microscope, X-Ray Spectrometer, Optical Metallurgical Microscope, Vickers Hardness, Universal Testing Machine and Abrasive Wear Testing Machine. A MLP (Multilayer Perceptron) feedforward was developed and used for modeling purpose. Training, testing and validation of the model were carried out using back propagation learning algorithm. The modeling results show that an architecture of 14 inputs with 9 hidden neurons and 4 outputs which includes the tensile strength, elongation, hardness and abrasive wear resistance gives reasonably accurate results with an error within the range of 2-7 % in training, testing and validation., Comment: 14 pages, Mehran University Research Journal of Engineering and Technology, Vol. 30, No.1, January 2011

Published
2016

28. Manufacturing of Aluminum Composite Material Using Stir Casting Process

Author

Jokhio, Muhammad Hayat, Panhwer, Muhammad Ibrahim, and Unar, Mukhtiar Ali

Subjects
Condensed Matter - Materials Science
Abstract

Manufacturing of aluminum alloy based casting composite materials via stir casting is one of the prominent and economical route for development and processing of metal matrix composites materials. Properties of these materials depend upon many processing parameters and selection of matrix and reinforcements. Literature reveals that most of the researchers are using 2, 6 and 7xxx aluminum matrix reinforced with SiC particles for high strength properties whereas, insufficient information is available on reinforcement of "Al2O3" particles in 7xxx aluminum matrix. The 7xxx series aluminum matrix usually contains Cu-Zn-Mg. Therefore, the present research was conducted to investigate the effect of elemental metal such as Cu-Zn-Mg in aluminum matrix on mechanical properties of stir casting of aluminum composite materials reinforced with alpha "Al2O3" particles using simple foundry melting alloying and casting route. The age hardening treatments were also applied to study the aging response of the aluminum matrix on strength, ductility and hardness. The experimental results indicate that aluminum matrix cast composite can be manufactured via conventional foundry method giving very good responses to the strength and ductility up to 10% "Al2O3" particles reinforced in aluminum matrix., Comment: 12 pages, Mehran University Research Journal of Engineering and Technology, Vol. 30, No. 1, January 2011

Published
2016

29. Intergenerational conflicts of interest and prosocial behavior during the COVID-19 pandemic

Author

Abakoumkin, Georgios, Khaiyom, Jamilah Hanum Abdul, Ahmedi, Vjollca, Akkas, Handan, Almenara, Carlos A., Kurapov, Anton, Atta, Mohsin, Bagci, Sabahat Cigdem, Basel, Sima, Kida, Edona Berisha, Buttrick, Nicholas R., Chobthamkit, Phatthanakit, Choi, Hoon-Seok, Cristea, Mioara, Csaba, Sára, Damnjanovic, Kaja, Danyliuk, Ivan, Dash, Arobindu, Di Santo, Daniela, Douglas, Karen M., Enea, Violeta, Faller, Daiane Gracieli, Fitzsimons, Gavan, Gheorghiu, Alexandra, Gómez, Ángel, Han, Qing, Helmy, Mai, Hudiyana, Joevarian, Jeronimus, Bertus F., Jiang, Ding-Yu, Jovanović, Veljko, Kamenov, Željka, Kende, Anna, Keng, Shian-Ling, Kieu, Tra Thi Thanh, Koc, Yasin, Kovyazina, Kamila, Kozytska, Inna, Krause, Joshua, Kruglanski, Arie W., Kutlaca, Maja, Lantos, Nóra Anna, Lemay, Edward P., Jr., Lesmana, Cokorda Bagus Jaya, Louis, Winnifred R., Lueders, Adrian, Malik, Najma, Martinez, Anton, McCabe, Kira O., Mehulić, Jasmina, Milla, Mirra Noor, Mohammed, Idris, Molinario, Erica, Moyano, Manuel, Muhammad, Hayat, Mula, Silvana, Muluk, Hamdi, Myroniuk, Solomiia, Najafi, Reza, Nisa, Claudia F., Nyúl, Boglárka, O'Keefe, Paul A., Osuna, Jose Javier Olivas, Osin, Evgeny N., Park, Joonha, Pica, Gennaro, Pierro, Antonio, Rees, Jonas, Reitsema, Anne Margit, Resta, Elena, Rullo, Marika, Ryan, Michelle K., Samekin, Adil, Santtila, Pekka, Sasin, Edyta, Schumpe, Birga Mareen, Selim, Heyla A., Stanton, Michael Vicente, Stroebe, Wolfgang, Sultana, Samiah, Sutton, Robbie M., Tseliou, Eleftheria, Utsugi, Akira, van Breen, Jolien Anne, Van Veen, Kees, van Dellen, Michelle R., Vázquez, Alexandra, Wollast, Robin, Yeung, Victoria Wai-lan, Zand, Somayeh, Žeželj, Iris Lav, Zheng, Bang, Zick, Andreas, Zúñiga, Claudia, Jin, Shuxian, Balliet, Daniel, Romano, Angelo, Spadaro, Giuliana, van Lissa, Caspar J., Agostini, Maximilian, Bélanger, Jocelyn J., Gützkow, Ben, Kreienkamp, Jannis, and Leander, N. Pontus

Published
2021
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30. The Precarity of Progress: Implications of a Shifting Gendered Division of Labor for Relationships and Well-Being as a Function of Country-Level Gender Equality

Author

Leerstoel Derks, Work and Organizational Psychology: Occupational Health Psychology, Fisher, Alexandra N., Ryan, Michelle K., Liao, Yuan Hsi, Mikołajczak, Gosia, Riedijk, Larisa, Leander, N. Pontus, Abakoumkin, Georgios, Abdul Khaiyom, Jamilah Hanum, Ahmedi, Vjollca, Agostini, Maximilian, Atta, Moshin, Bagci, Sabahat Cigdem, J. Bélanger, Jocelyn, Berisha Kida, Edona, B. I. Bernardo, Allan, Chobthamkit, Phatthanakit, Choi, Hoon Seok, Cristea, Mioara, Damnjanovic, Kaja, Danyliuk, Ivan, Di Santo, Daniela, M. Douglas, Karen, Enea, Violeta, J. Fitzsimons, Gavan, Gómez, Ángel, Gützkow, Ben, Hamaidia, Ali, Helmy, Mai, Hudiyana, Joevarian, Jovanović, Veljko, Kende, Anna, Keng, Shian Ling, Kieu, Tra Thi Thanh, Koc, Yasin, Kreienkamp, Jannis, Kurapov, Anton, Lantos, Nóra Anna, P. Lemay, Edward, Lueders, Adrian, Malik, Najma Iqbal, O. McCabe, Kira, Mehulić, Jasmina, Molinario, Erica, Moyano, Manuel, Muhammad, Hayat, Muluk, Hamdi, F. Nisa, Claudia, Nyúl, Boglárka, A. O’Keefe, Paul, Olivias Osuna, Jose Javier, Osin, Evgeny, Park, Joonha, Pica, Gennaro, Pierro, Antonio, Rees, Jonas, Reitsema, Anne Margit, Rullo, Marika, Samekin, Adil, M. Schumpe, Birga, A. Selim, Heyla, Stanton, Michael Vicente, Tseliou, Eleftheria, R vanDellen, Michelle, Vázquez, Alexandra, Wollast, Robin, Yeung, Victoria Wai Lan, Zand, Somayeh, Žeželj, Iris Lav, Zúñiga, Claudia, Leerstoel Derks, Work and Organizational Psychology: Occupational Health Psychology, Fisher, Alexandra N., Ryan, Michelle K., Liao, Yuan Hsi, Mikołajczak, Gosia, Riedijk, Larisa, Leander, N. Pontus, Abakoumkin, Georgios, Abdul Khaiyom, Jamilah Hanum, Ahmedi, Vjollca, Agostini, Maximilian, Atta, Moshin, Bagci, Sabahat Cigdem, J. Bélanger, Jocelyn, Berisha Kida, Edona, B. I. Bernardo, Allan, Chobthamkit, Phatthanakit, Choi, Hoon Seok, Cristea, Mioara, Damnjanovic, Kaja, Danyliuk, Ivan, Di Santo, Daniela, M. Douglas, Karen, Enea, Violeta, J. Fitzsimons, Gavan, Gómez, Ángel, Gützkow, Ben, Hamaidia, Ali, Helmy, Mai, Hudiyana, Joevarian, Jovanović, Veljko, Kende, Anna, Keng, Shian Ling, Kieu, Tra Thi Thanh, Koc, Yasin, Kreienkamp, Jannis, Kurapov, Anton, Lantos, Nóra Anna, P. Lemay, Edward, Lueders, Adrian, Malik, Najma Iqbal, O. McCabe, Kira, Mehulić, Jasmina, Molinario, Erica, Moyano, Manuel, Muhammad, Hayat, Muluk, Hamdi, F. Nisa, Claudia, Nyúl, Boglárka, A. O’Keefe, Paul, Olivias Osuna, Jose Javier, Osin, Evgeny, Park, Joonha, Pica, Gennaro, Pierro, Antonio, Rees, Jonas, Reitsema, Anne Margit, Rullo, Marika, Samekin, Adil, M. Schumpe, Birga, A. Selim, Heyla, Stanton, Michael Vicente, Tseliou, Eleftheria, R vanDellen, Michelle, Vázquez, Alexandra, Wollast, Robin, Yeung, Victoria Wai Lan, Zand, Somayeh, Žeželj, Iris Lav, and Zúñiga, Claudia

Published
2024

32. Predictors of Preterm Neonatal Mortality in India and Pakistan: A Secondary Analysis of Data from PURPOSe Study

Author

Tikmani, Shiyam Sunder, primary, Saleem, Sarah, additional, Sadia, Afreen, additional, M. Bann, Carla, additional, Bozdar, Muhammad Hayat, additional, Raza, Jamal, additional, Dhaded, Sangappa M., additional, Goudar, Shivaprasad S., additional, Gowdar, Guruparasad, additional, Yasmin, Haleema, additional, McClure, Elizabeth M., additional, and Goldenberg, Robert L., additional

Published
2024
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33. A Critical Study of Blasphemy Laws of Pakistan and their Impact on the Minorities of the Country

Author

Abdul Muhaimin Khan and Muhammad Hayat Khan

Subjects
blasphemy, ḥanafī school of thought, qur’ān, ḥadith, sharī‘at, four rightly guided caliphs, umayyad, abbasids, Islam, BP1-253, Islamic law, KBP1-4860
Abstract

The blasphemy laws are the parts of Pakistan Penal Code which were set up by the British regime in 1860. These laws were aimed to safeguard the religious feelings of the followers of various beliefs. The laws encompassed all the religions who lived in the subcontinent. It is also said that the sections 295-B and 295-C which were introduced in 1980s are meant to shield only one religion and that is Islam. This research has critically examined the blasphemy laws of Pakistan and their impacts on the status of non-Muslims living in the country. The study has highlighted views of the adherents and the opponents of these laws. It gives a fact sheet of what has happened so far in the country in terms of the outcomes of these laws. The research includes a recent survey on issue related to blasphemy and it ends up with few recommendations.

Published
2020
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35. A Quasi Experimental study to Compare Thermo-regulator blanket with conventional method (incubator) for temperature regulations in preterm, Low Birth weight neonates landing at Emergency department of a tertiary care pediatric facility

Author

Murtaza Ali Gowa, Allah Rakhia, Muhammad Hayat Bozdar, Mehboob Noonari, and Syed Jamal Raza

Subjects
Medicine
Abstract

Objective: To compare incubator and thermal blanket for thermoregulation in preterm and low birth weight neonates. Method: The pilot study was conducted from January to March 2018 at the emergency department of the National Institute of Child Health, Karachi, and comprised preterm and low birth weight neonates without any co-morbidity who were randomised to control and interventional groups. Data was collected using a proforma about demographics, weight, gestational age and brief clinical history. Temperature, blood pressure and pulse were monitored along with other routine care after every 15 minutes in the incubator, and the same procedure was adopted for thermal blankets. Data was analysed using Statistical Package for Social Sciences (SPSS) Version 23. Results: Of the 38 subjects, 19(50%) each were cases and controls. The mean gestational age between the groups was not significantly different (p>0.05). Temperature for the first 60 minutes remained similar in the two groups, but at 75 minutes and onwards, the incubator showed a significantly better results (p

Published
2022
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36. An In situ neutron diffraction study of phase formation during Ti–Si3N4 powder sintering

Author

Harshpreet Singh, Muhammad Hayat, Saifang Huang, Yanwei Sui, and Peng Cao

Subjects
Titanium, Neutron diffraction, Sintering, Ti composite, Phase formation, Mining engineering. Metallurgy, TN1-997
Abstract

This paper characterises and evaluates Si3N4/Ti composites during thermal treatment using an in situ neutron diffraction technique. The composites were developed using a conventional press and sinter technique. Pure titanium (Ti) was chosen as the matrix, and different concentrations of Si3N4 were used as the reinforcement. The effects of sintering temperature and the concentration of Si3N4 in the Ti matrix were investigated with respect to phase constituents. The Si3N4 mass fraction in the Ti matrix was found to be the key parameter for the reaction. Because of its instability in Ti at higher temperatures, in situ reactions between the reinforcing particles and matrix led to the formation of intermetallic compounds, such as Ti5Si3 and possibly Ti3Si, in the composites containing higher weight fractions of Si3N4.

Published
2022
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37. Lives versus Livelihoods? Perceived economic risk has a stronger association with support for COVID-19 preventive measures than perceived health risk

Author

Nisa, Claudia F., Bélanger, Jocelyn J., Faller, Daiane G., Buttrick, Nicholas R., Mierau, Jochen O., Austin, Maura M. K., Schumpe, Birga M., Sasin, Edyta M., Agostini, Maximilian, Gützkow, Ben, Kreienkamp, Jannis, Abakoumkin, Georgios, Abdul Khaiyom, Jamilah Hanum, Ahmedi, Vjollca, Akkas, Handan, Almenara, Carlos A., Atta, Mohsin, Bagci, Sabahat Cigdem, Basel, Sima, Kida, Edona Berisha, Bernardo, Allan B. I., Chobthamkit, Phatthanakit, Choi, Hoon-Seok, Cristea, Mioara, Csaba, Sára, Damnjanović, Kaja, Danyliuk, Ivan, Dash, Arobindu, Di Santo, Daniela, Douglas, Karen M., Enea, Violeta, Fitzsimons, Gavan, Gheorghiu, Alexandra, Gómez, Ángel, Grzymala-Moszczynska, Joanna, Hamaidia, Ali, Han, Qing, Helmy, Mai, Hudiyana, Joevarian, Jeronimus, Bertus F., Jiang, Ding-Yu, Jovanović, Veljko, Kamenov, Željka, Kende, Anna, Keng, Shian-Ling, Kieu, Tra Thi Thanh, Koc, Yasin, Kovyazina, Kamila, Kozytska, Inna, Krause, Joshua, Kruglanski, Arie W., Kurapov, Anton, Kutlaca, Maja, Lantos, Nóra Anna, Lemay, Jr., Edward P., Lesmana, Cokorda Bagus Jaya, Louis, Winnifred R., Lueders, Adrian, Malik, Najma Iqbal, Martinez, Anton, McCabe, Kira O., Mehulić, Jasmina, Milla, Mirra Noor, Mohammed, Idris, Molinario, Erica, Moyano, Manuel, Muhammad, Hayat, Mula, Silvana, Muluk, Hamdi, Myroniuk, Solomiia, Najafi, Reza, Nyúl, Boglárka, O’Keefe, Paul A., Osuna, Jose Javier Olivas, Osin, Evgeny N., Park, Joonha, Pica, Gennaro, Pierro, Antonio, Rees, Jonas, Reitsema, Anne Margit, Resta, Elena, Rullo, Marika, Ryan, Michelle K., Samekin, Adil, Santtila, Pekka, Selim, Heyla A., Stanton, Michael Vicente, Sultana, Samiah, Sutton, Robbie M., Tseliou, Eleftheria, Utsugi, Akira, van Breen, Jolien Anne, Van Lissa, Caspar J., Van Veen, Kees, vanDellen, Michelle R., Vázquez, Alexandra, Wollast, Robin, Yeung, Victoria Wai-lan, Zand, Somayeh, Žeželj, Iris Lav, Zheng, Bang, Zick, Andreas, Zúñiga, Claudia, and Leander, N. Pontus

Published
2021
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38. Effect of Animal Age, Postmortem Calcium Chloride Marination, and Storage Time on Meat Quality Characteristics of M. longissimus thoracis et lumborum of Buffalo Bulls

Author

Muawuz Ijaz, Muhammad Hayat Jaspal, Muhammad Usman Akram, Iftikhar Hussain Badar, Muhammad Kashif Yar, Raheel Suleman, Adeel Manzoor, Muhammad Farooq, Sher Ali, Zubair Hussain, Mubarik Mahmood, Abdur Rahman, and Rao Sharafat Ali

Subjects
buffalo meat, spent buffalo, carabeef, calcium chloride, marination, shelf life, Chemical technology, TP1-1185
Abstract

This study investigated the effect of animal age, calcium chloride marination, and storage time on meat quality characteristics of buffalo bulls to suggest a cost-effective method of improving buffalo meat quality. The current study was designed considering the importance of buffalo meat and the usage of meat from spent buffalo animals in local markets of South Asian countries. A total of 36 animals comprised of 18 young and 18 spent buffalo bulls were selected. After slaughtering and 24 h of postmortem chilling, striploins were separated and cut into 16 steaks and equally divided into two groups, i.e., either marinated with calcium chloride or not. Meat quality characteristics were recorded on 0, 2, 4, 6, 8, and 10 days of storage. The results showed that the pH value of young animals was higher than the value of spent animals and pH was increased over the storage time. Color b*, C*, and h* values were higher in spent animals as compared with the young animals; however, values of colors L* and h* were higher and a* was lower in marinated samples than the values of non-marinated samples. Color a* and C* values were increased and h* was decreased with lengthening the storage time. The meat cooking loss was higher in marinated and the water-holding capacity was higher in non-marinated meat samples. Shear force values were lower in young animals and marinated samples than the values of spent animals and non-marinated meat samples, respectively. Sensory characteristic scores of marinated samples were better than the non-marinated samples. In conclusion, calcium chloride marination can be used to improve the quality characteristics of buffalo meat.

Published
2022
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40. Conceptual replication and extension of health behavior theories' predictions in the context of COVID‐19: Evidence across countries and over time

Author

Abakoumkin, Georgios, primary, Tseliou, Eleftheria, additional, McCabe, Kira O., additional, Lemay, Edward P., additional, Stroebe, Wolfgang, additional, Agostini, Maximilian, additional, Bélanger, Jocelyn J., additional, Gützkow, Ben, additional, Kreienkamp, Jannis, additional, Kutlaca, Maja, additional, VanDellen, Michelle R., additional, Abdul Khaiyom, Jamilah Hanum, additional, Ahmedi, Vjollca, additional, Akkas, Handan, additional, Almenara, Carlos A., additional, Atta, Mohsin, additional, Bagci, Sabahat Cigdem, additional, Basel, Sima, additional, Berisha Kida, Edona, additional, Bernardo, Allan B. I., additional, Buttrick, Nicholas R., additional, Chobthamkit, Phatthanakit, additional, Choi, Hoon‐Seok, additional, Cristea, Mioara, additional, Csaba, Sára, additional, Damnjanovic, Kaja, additional, Danyliuk, Ivan, additional, Di Santo, Daniela, additional, Douglas, Karen M., additional, Enea, Violeta, additional, Faller, Daiane Gracieli, additional, Fitzsimons, Gavan, additional, Gheorghiu, Alexandra, additional, Gómez, Ángel, additional, Grzymala‐Moszczynska, Joanna, additional, Hamaidia, Ali, additional, Han, Qing, additional, Helmy, Mai, additional, Hudiyana, Joevarian, additional, Jeronimus, Bertus F., additional, Jiang, Ding‐Yu, additional, Jovanović, Veljko, additional, Kamenov, Željka, additional, Kende, Anna, additional, Keng, Shian‐Ling, additional, Kieu, Tra Thi Thanh, additional, Koc, Yasin, additional, Kovyazina, Kamila, additional, Kozytska, Inna, additional, Krause, Joshua, additional, Kruglanski, Arie W., additional, Kurapov, Anton, additional, Lantos, Nóra Anna, additional, Lesmana, Cokorda Bagus Jaya, additional, Louis, Winnifred R., additional, Lueders, Adrian, additional, Malik, Najma Iqbal, additional, Martinez, Anton, additional, Mehulić, Jasmina, additional, Milla, Mirra Noor, additional, Mohammed, Idris, additional, Molinario, Erica, additional, Moyano, Manuel, additional, Muhammad, Hayat, additional, Mula, Silvana, additional, Muluk, Hamdi, additional, Myroniuk, Solomiia, additional, Najafi, Reza, additional, Nisa, Claudia F., additional, Nyúl, Boglárka, additional, O’Keefe, Paul A., additional, Olivas Osuna, Jose Javier, additional, Osin, Evgeny N., additional, Park, Joonha, additional, Pica, Gennaro, additional, Pierro, Antonio, additional, Rees, Jonas, additional, Reitsema, Anne Margit, additional, Resta, Elena, additional, Rullo, Marika, additional, Ryan, Michelle K., additional, Samekin, Adil, additional, Santtila, Pekka, additional, Sasin, Edyta, additional, Schumpe, Birga Mareen, additional, Selim, Heyla A., additional, Stanton, Michael Vicente, additional, Sultana, Samiah, additional, Sutton, Robbie M., additional, Utsugi, Akira, additional, van Breen, Jolien Anne, additional, Van Lissa, Caspar J., additional, Van Veen, Kees, additional, Vázquez, Alexandra, additional, Wollast, Robin, additional, Yeung, Victoria Wai‐lan, additional, Zand, Somayeh, additional, Žeželj, Iris Lav, additional, Zheng, Bang, additional, Zick, Andreas, additional, Zúñiga, Claudia, additional, and Leander, N. Pontus, additional

Published
2023
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42. SENESCENCE OR APOPTOSIS: CHONDROCYTE RESPONSE TO INFLAMMATION IN VITRO IS DEPENDENT ON ITS DIMENSIONAL ENVIRONMENT

Author

Strangmark, Estelle, primary, Wang, Jia Hua, additional, Hosni, Rawiya Al, additional, Muhammad, Hayat, additional, Alkhrayef, Mohammad, additional, Robertson-Waters, Eve, additional, MacMillan, Alexandra, additional, Gompels, Benjamin, additional, Vogt, Antonia, additional, Khan, Wasim, additional, Birch, Mark, additional, and McCaskie, Andrew, additional

Published
2023
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43. Age, sex, and chilling effects on goat meat

Author

Farid, Muhammad Umar, primary, Jaspal, Muhammad Hayat, additional, Luqman, Nida, additional, Asghar, Bilal, additional, Ijaz, Muawuz, additional, Yar, Muhammad Kashif, additional, Ali Taseer, Muhammad Sulman, additional, Iqbal, Zeeshan, additional, Naeem, Muhammad Ahsan, additional, and Nasir, Jamal, additional

Published
2023
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44. An Analytical Study of the Outcomes and Impacts of Religious Education of Pakistan, the Challenges and Opportunities

Author

Dr. Abdul Muhaimin, Dr. Atta Ullah, and Muhammad Hayat Khan

Subjects
religious, education, madāris, ijtihād, Islam, BP1-253, Religions. Mythology. Rationalism, BL1-2790
Abstract

This study focuses on the impact of Religious Education in Pakistan at individual and collective levels. The research discusses the educational basis for the study of religion and analyzes the contribution of religious education towards the intellectual growth of individuals. The study raises few questions regarding religious education in Pakistan such as; why has our education system been divided into religious and secular education system. Whether the existing religious education is able to create a linkage between religion and society or not, if not what are the areas which need to be focused. What are the possibilities of sidelining the religious education and what could be its effects. The research focuses on the aims and objectives or religious education in Pakistan by analyzing the nature of curriculums of religious education at various levels. This study highlights the deficiency of the inclusion of the teachings of other religions in our religious education. The research consists of a current survey of the said topic, some findings and conclusions on the issue and few recommendations as well.

Published
2019
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45. Molecular phylogeny of Artemisia (Asteraceae-Anthemideae) with emphasis on undescribed taxa from Gilgit-Baltistan (Pakistan) based on nrDNA (ITS and ETS) and cpDNA (psbA-trnH) sequences

Author

Adil Hussain, Daniel Potter, Sangtae Kim, Muhammad Hayat, and Syed Bokhari

Subjects
Artemisia, Asteraceae, nrDNA, cpDNA, molecular phy, Plant ecology, QK900-989
Abstract

Background – Gilgit-Baltistan, the Northeast region of Pakistan, is well known for its floristic diversity, including members of the genus Artemisia. Artemisia is a large, taxonomically complex genus including ~500 species of both herbs and shrubs. This study was conducted to determine the phylogenetic position of ten undescribed Artemisia taxa from northern Pakistan, using nrDNA internal transcribed spacer (ITS), external transcribed spacer (ETS) and cpDNA intergenic spacer (psbA-trnH) regions.Methods – The phylogenetic relationships of 28 taxa of Artemisia using separate and combined data sets of sequences of three markers (ITS, ETS and psbA-trnH) were analysed with maximum parsimony, maximum likelihood, and Bayesian approaches. Key results – The results resolve northeastern Pakistani Artemisia, which represent five morphologically defined subgenera, into ten major clades. Subgenera Artemisia and Absinthium are shown to be polyphyletic, while Dracunculus, Pacifica and Tridentatae appear monophyletic. All species of subgenus Seriphidium are retrieved in a single clade that also includes annual species from subgenus Artemisia. In the Flora of Pakistan, Seriphidium is described as a separate genus but in this study, Seriphidium fell within the genus Artemisia. In addition, on the basis of phylogenetic analysis, we present evidence that ten as-yet undescribed taxa are present in northeastern Pakistan based on newly recognized three groups (Groups I, II and III) of taxa within the genus Artemisia. One undescribed taxon from group I was placed within the subgenus Dracunculus clade and the remaining nine taxa from groups II and III were placed in the subgenus Absinthium clade. Morphological studies coupled with modern molecular techniques may lead to a new infrageneric classification of the genus Artemisia. It will also clarify and characterize the undescribed taxa reported in this study.

Published
2019
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46. Effect of Cryogenic Treatment on Mechanical Properties of AISI 4340 and AISI 4140 Steel

Author

Abdul Rauf Jamali, Waseem Khan, Ali Dad Chandio, Zubai Anwer, and Muhammad Hayat Jokhio

Subjects
Technology, Engineering (General). Civil engineering (General), TA1-2040, Science
Abstract

From last epoch till to date, AISI 4340 and AISI 4140 have been widely used in different engineering applications. These applications include bolt, screws, gears, drive shafts, crane shaft and piston rods for engines due to its upright mechanical properties, cost-effective and easily available in market. In present work, deep cryogenic treatment effect on the mechanical properties of AISI 4340 and AISI 4140 have been studied. Present work was carried out at laboratory scale and can be extended for mass production. Our work is simple, straight forward safe and economical. In our work, samples were heat treated in simple muffle furnace and followed by cryogenic treatment in liquid nitrogen. Before cryogenic treatment, all samples were normalized at 860°C to obtain homogenized microstructure. Samples were also compared conventionally heat treatment with quenched in oil quenchant. Experimental results showed that after cryogenic treatment with tempering treatment, one could easily increase the tensile strength, impact toughness and hardness. Advanced optical microscopy (IMM 901) and SEM (Scanning Electron Microscopy), FIT Quanta 200 methods have also been deployed to reveal and interpret the internal structure of samples. It was found from microstructure that cryogenic treated sample increases the impact strength, hardness and tensile strength as compared conventional heat treated quenching approaches.

Published
2019

47. Examples of Accountability Process in Seerah: Appropriate Study of Duties of the Wafaqi Mohtasib (Federal Ombudsman), Pakistan= سیرت النبی ﷺ میں احتسابی عمل کی مثالیں:وفاقی محتسب پاکستان کے فرائض کا اختصاصی مطالعہ

Author

Dr. Muhammad Ikramullah and Muhammad Hayat Khan

Subjects
federal ombudsman, seerah, individual rights, public complaints, government initiatives, Islam, BP1-253, Religions. Mythology. Rationalism, BL1-2790
Abstract

In any society, the administration has a status of a pillar, and its good, bad move, directly impacts on society. There are institutions to compensate public complaints on government initiatives in many countries of the world that account for government workers. This institution in Pakistan is established as "Federal Ombudsman". Main responsibilities of this institute include the execution of Amr bil Mar’ūf and Nahi ‘An al Munkar, monitoring government employees, monitoring administrative matters, to hear the complaints of public against organizations and preventing them from violating individual rights. In this article, it has been reviewed that what type of guidance of the Prophet (peace be upon him) is in this matter, in order to evaluate the present system of "Federal Ombudsman" and bring it according to the guidance of Prophet Hood by removing the defects in it. Following the observation of the main responsibilities of the "Federal Ombudsman" in the paper, the guidance received from examples present in the Seerah was described, and recommendations have been made for further improvement after describing the results obtained from them.

Published
2019
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48. Antioxidant properties of Milk and dairy products: a comprehensive review of the current knowledge

Author

Imran Taj Khan, Muhammad Nadeem, Muhammad Imran, Rahman Ullah, Muhammad Ajmal, and Muhammad Hayat Jaspal

Subjects
Antioxidants activity, Milk, Carotenoids, Enzymatic antioxidants, Phytochemicals, Nutritional diseases. Deficiency diseases, RC620-627
Abstract

Abstract Milk and dairy products are integral part of human nutrition and they are considered as the carriers of higher biological value proteins, calcium, essential fatty acids, amino acids, fat, water soluble vitamins and several bioactive compounds that are highly significant for several biochemical and physiological functions. In recent years, foods containing natural antioxidants are becoming popular all over the world as antioxidants can neutralize and scavenge the free radicals and their harmful effects, which are continuously produced in the biological body. Uncontrolled free radicals activity can lead to oxidative stresses, which have been implicated in breakdown of vital biochemical compounds such as lipids, protein, DNA which may lead to diabetes, accelerated ageing, carcinogenesis and cardiovascular diseases. Antioxidant capacity of milk and milk products is mainly due to sulfur containing amino acids, such as cysteine, phosphate, vitamins A, E, carotenoids, zinc, selenium, enzyme systems, superoxide dismutase, catalase, glutathione peroxidase, milk oligosaccharides and peptides that are produced during fermentation and cheese ripening. Antioxidant activity of milk and dairy products can be enhanced by phytochemicals supplementation while fermented dairy products have been reported contained higher antioxidant capacity as compared to the non-fermented dairy products. Literature review has shown that milk and dairy products have antioxidant capacity, however, information regarding the antioxidant capacity of milk and dairy products has not been previously compiled. This review briefly describes the nutritional and antioxidant capacity of milk and dairy products.

Published
2019
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50. Meat Production and Supply Chain Under COVID-19 Scenario: Current Trends and Future Prospects

Author

Muawuz Ijaz, Muhammad Kashif Yar, Iftikhar Hussain Badar, Sher Ali, Md. Shafiqul Islam, Muhammad Hayat Jaspal, Zafar Hayat, Aneeqa Sardar, Sana Ullah, and Denise Guevara-Ruiz

Subjects
COVID-19, meat sector, supply chain, price fluctuation, meat production, Veterinary medicine, SF600-1100
Abstract

The COVID-19 pandemic impacted meat production, supply chain, and meat prices that caused a severe socio-economic crisis worldwide. Initially, meat and meat products' prices increased due to less production and increased demand because of panic buying. Whereas, later on, both meat production and demand were significantly decreased due to lockdown restrictions and lower purchasing power of the consumers that results in a decrease in meat prices. In early April 2020, meat packing facilities started to shut down due to the rapid spread of the COVID-19 virus among workers. Furthermore, meat producers and processors faced difficulty in harvesting and shipment of the products due to lockdown situations, decrease in labor force, restrictions in movement of animals within and across the country and change in legislation of local and international export market. These conditions adversely impacted the meat industry due to decrease in meat production, processing and distribution facilities. It is suggested that the integration among all the meat industry stakeholders is quite essential for the sustainability of the industry's supply chain to cope with such devastating conditions the future may hold. This review aimed to discuss different aspects of the meat industry and supply chain during the COVID-19 pandemic and proposed some future directions.

Published
2021
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