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168 results on '"Mulcahy, M. F."'

21. Irish Society of Gastroenterology — Summer Meeting Held at Educational Centre, Althnagelvin Area Hospital, Londonderry on Friday 5th and Saturday 6th June, 1987

Author

Geraghty, J. G., Burke, P. E., McGovern, E., Shaw, K. M., Tobin, A., O’Leary, D., Dillon, M. E., O’Morain, C., Doyle, C. T., Brady, Caitriona, Gibney, M. J., Kelly, S. B., Wall, J., Panesar, K. J. S., O’Donohoe, M. K., Blake, A., Waldron, R. P., Dervan, P., Fitzpatrick, J. M., Cotter, P., Burke, G. J., Moran, K., McEntee, G., Jones, B., Duignan, J. P., Hone, R., O’Malley, E., Brennan, F., Whitehead, H., O’Connor, F. A., O’Dwyer, P. J., Martin, E. W., Kelly, S. B., Hershman, M. J., Habib, N. A., Williamson, R. C. N., Spencer, J., Wood, C. B., Kelly, Jacinta, Weir, D. G., Feighery, C., Doyle, C. T., Hanjavanit, C., Mulcahy, M. F., Courtney, M. G., Daly, P. A., Temperley, I. J., Keeling, P. W. N., Weir, D. G., Keating, J. J., Maxwell, W. J., Hogan, F. P., Keeling, P. W. N., McColl, Teresa, O’Leary, D., O’Morain, C. A., O’Connell, P. R., Horgan, P. G., Kirwan, W. O., O’Reilly, T., MacMathuna, P., Keeling, P. W. N., Feely, J., MacGowan, S. W., Bouchier-Hayes, D. J., Broe, P. J., Kennedy, N. P., Walsh, J. P., Maxwell, W. P., Hogan, F. P., Keeling, P. W. N., Coghlan, G., Gilligan, D., Humphries, H., McKenna, D., Dooley, C., Sweeney, E., Keane, C., O’Morain, C., O’Mahony, S., Whelton, M. J., Kearney, J., Keating, J., Kennedy, N., Keeling, P. W. N., Gibney, M. J., Deasy, J., Primrose, J., Holdsworth, P., Quirk, P., Dixon, M., Johnston, D., Healy, M., O’Connor, M. P., Weir, D. G., Keane, C. T., O’Moore, R. R., Nally, C. V., McMullin, L. J., Cianachan, A. S., Scott, G. W., O’Connor, M. P., Healy, M., Keane, C. T., O’Moore, R. R., Weir, D. G., Walsh, T. N., O’Malley, V. P., Given, H. F., O’Connor, H. J., Burrows, F. G., Neuberger, J., Elias, E., Kennedy, M. M., Hayes, M., Gibney, M. J., Keeling, P. W. N., Collins, A. -M., O’Connor, M. P., Weir, D. G., Gibney, M., Keeling, P., O’Sullivan, G., Kent, P., Gillen, P., Hennessy, T. P. J., Maxwell, W. J., Hogan, F. P., Keating, J. J., Keeling, P. W. N., Deasy, J. M., Lavelle, J. P., Clery, A. P., Coghlan, G., Gilligan, D., Humphries, H., McKenna, D., Sweeney, E., Keane, C., and O’Morain, C.

Published
1988
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22. Bonamia ostreae in the Native Oyster Ostrea edulis

Author

Culloty, S. C. and Mulcahy, M. F.

Subjects
MEHS
Abstract

Ireland has a long history of producing and harvesting native flat oysters, Ostrea edulis. At the start of the nineteenth century, almost every bay and harbour, around the coast had abundant beds of native oysters. Intensive dredging to meet the demands of the markets in Dublin and England depleted the stocks, so that in 1845 the government passed legislation to permit the formation of private oyster beds to improve the ailing stocks. According to the book on “Shellfish & Shellfisheries of Ireland” (Wilkins, 2004) Irish stocks began to collapse between 1850 and 1860. By the second half of the twentieth century, only the beds of Tralee Bay, Galway Bay and Clew Bay were still yielding a good return for local fishermen. The arrival of the oyster parasite Bonamia ostreae in the mid 1980s was an additional blow to the Irish native oyster stocks. This report sets out to document the spread and the impact of the Bonamia ostreae parasite in Irish bays since the 1980s., Funder: Marine Institute

Published
2007

31. Effect of hyperacute immunotherapy in addition to standard adjuvant therapy for resected pancreatic cancer on disease-free and overall survival: Preliminary analysis of phase II data.

Author

Hardacre, J. M., primary, Mulcahy, M. F., additional, Talamonti, M., additional, Obel, J. C., additional, Rocha Lima, C. S., additional, Safran, H., additional, Rossi, G. R., additional, Tennant, L., additional, Vahanian, N. N., additional, and Link, C. J., additional

Published
2010
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34. E2205: A phase II study to measure response rate and toxicity of neoadjuvant chemoradiotherapy (CRT) with oxaliplatin (OX) and infusional 5-fluorouracil (5-FU) plus cetuximab (C) followed by postoperative docetaxel (DT) and C in patients with operable adenocarcinoma of the esophagus.

Author

Gibson, M. K., primary, Catalano, P. J., additional, Kleinberg, L., additional, Staley, C. A., additional, Montgomery, E., additional, Song, W., additional, Mulcahy, M. F., additional, Leichman, L. P., additional, and Benson, A. B., additional

Published
2010
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40. A double-blind, placebo-controlled, randomized phase III trial of gemcitabine (G) plus bevacizumab (B) versus gemcitabine plus placebo (P) in patients (pts) with advanced pancreatic cancer (PC): A preliminary analysis of Cancer and Leukemia Group B (CALGB

Author

Kindler, H. L., primary, Niedzwiecki, D., additional, Hollis, D., additional, Oraefo, E., additional, Schrag, D., additional, Hurwitz, H., additional, McLeod, H. L., additional, Mulcahy, M. F., additional, Schilsky, R. L., additional, and Goldberg, R. M., additional

Published
2007
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42. Susceptibility of a number of bivalve species to the protozoan parasite Bonamia ostreae and their ability to act as vectors for this parasite

Author

Culloty, S. C., Novoa, Beatriz, Pernas, María, Longshaw, Matt, Mulcahy, M. F., Feist, Stephen W., Figueras Huerta, Antonio, Culloty, S. C., Novoa, Beatriz, Pernas, María, Longshaw, Matt, Mulcahy, M. F., Feist, Stephen W., and Figueras Huerta, Antonio

Abstract

The protozoan parasite Bonamia ostreae (Pichot et al., 1980) is a serious pathogen of the native European flat oyster Ostrea edulis. Field and laboratory based experiments were carried out in Ireland and Spain to investigate the susceptibility to this protozoan of the Pacific oyster Crassostrea gigas, the mussels Mytilus edulis and Mytilus galloprovincialis, the European native clam Ruditapes decussatus and the Manila clam Ruditapes philippinarum. Their ability to act as vectors or intermediate hosts was also investigated. The study corroborated previous findings that demonstrated that flat oysters can be successfully infected both naturally in the field and experimentally in the laboratory, and the pathogen can be transmitted directly between flat oysters in the laboratory. However, the other bivalves tested could not be infected with the parasite either naturally or experimentally, and these bivalves did not appear to act as vectors or intermediate hosts for the parasite. These results have implications for movements of bivalves between areas within the European Union.

Published
1999

45. Environmental risk factors associated with amoebic gill disease in cultured salmon,Salmo salarL., smolts in Ireland.

Author

Bermingham, M L and Mulcahy, M F

Subjects
*BACTERIAL gill disease, *BACTERIAL diseases in fishes, *ATLANTIC salmon, *CILIATA, *FISH diseases, *VIRUS diseases in fishes
Abstract

A 2-year study was carried out on amoebic gill disease (AGD) involving monthly samples of 1+ Atlantic salmon,Salmo salarL., smolts, histological assessment of the gills and analysis of environmental data. Gill pathology was seen before amoebae could be detected microscopically. These changes in gill integrity were associated with marine environmental conditions, particularly elevated ammonium, nitrite and chlorophyll levels. The results suggest that the environmental changes predispose salmon to colonization by amoebae and ciliates. High densities of histophagous scuticociliates were observed in the gills during periods of advanced gill pathology. A number of different amoebae were observed in close association with gill pathology.Neoparamoebawas not seen in high densities, nor was it associated with gill pathology, indicating thatNeoparamoebamay not be the primary agent of the AGD in Irish salmonid culture. [ABSTRACT FROM AUTHOR]

Published
2004
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47. COMPARISON OF TECHNIQUES FOR DIAGNOSIS OF BROWN RING DISEASE AND DETECTION OF VIBRIO TAPETIS IN THE MANILA CLAM, VENERUPIS (RUDITAPES) PHILIPPINARUM.

Author

Drummond, L. C., O'Reilly, P., Mulcahy, M. F., and Culloty', S. C.

Abstract

The bacterium, Vibrio tapetis, is the aetiological agent of Brown Ring Disease (BRD), which affects the Manila clam, Venerupis (Ruditapes) philippinarum. Two PCR assays for detection of V. tapetis were applied to a sample of 52 Manila clams, and evaluated in comparison with the more traditional V. tapetis detection method of microbiological isolation and characterization, as well as the traditional BRD diagnostic technique of shell valve analysis. The pathogen was detected in 15.4% of the sample using the PCR assay of Rodríguez et al. (2003, 2006) in 50% of the sample using the PCR assay of Paillard et al. (2006) and in 36.5% of the sample by microbiological methods. Whereas shell valve analysis was the least sensitive technique, detecting BRD in 7.7% of the sample, it was an essential diagnostic tool because it was the only technique that identified the disease, rather than the aetiological agent. None of the four techniques was sufficient on its own for effective BRD diagnosis; rather various combinations of two techniques were the minimum required. The combination of shell valve analysis with the assay of Paillard et al. (2006) proved to be the most sensitive and rapid of those tested. Shell valve analysis was the most time-efficient and cost-effective technique, whereas microbiological characterization was the most time-consuming, and PCR detection, using either set of primers, the most expensive. These results may need to be considered in light of diagnosis and management of BRD. [ABSTRACT FROM AUTHOR]

Published
2006
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48. THE SUSCEPTIBILITY OF YOUNG PRESPAWNING OYSTERS, OSTREA EDULIS, TO BONAMIA OSTREAE.

Author

Lynch, S. A., Armitage, D. V., Wylde, S., Mulcahy, M. F., and Culloty, S. C.

Abstract

Young prespawning oysters, Ostrea edulis, were held over 6 mo at two different Bonamia ostreae-endemic sites in Ireland, to determine to what extent they could become infected with this protozoan parasite. Prevalence and intensity of infection were monitored, using the traditional method of ventricular heart smears and polymerase chain reaction (PCR). Results showed that 0+ and 1+ oysters were susceptible to infection. Infection was observed in the naïve and previously exposed oysters 2 months post relaying. Of ventricular heart smears and PCR, PCR was the more sensitive diagnostic technique in detecting B. ostreae in most of the oysters. Current methods recommended by the Office International Epizooties (OlE) and the European Union (EU), histology and screening of heart smears for B. ostreae, may be inadequate because certain low levels of infection may go undetected. [ABSTRACT FROM AUTHOR]

Published
2005
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