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Disposable diapers are considered indispensable hygiene products, which is reflected in their massive levels of consumption globally and waste generation. Most of the diaper waste is neither segregated nor treated and ends up in landfills or incinerators. The reported life cycle assessment highlights that the diaper waste is not solely generated after single-use but begins as early as the raw materials acquisition stage. Although what is done cannot be undone, diaper waste can be recycled. Diaper waste valorization has been explored on laboratory- and commercial-scales for years, with varying degrees of success. Leading diaper manufacturers such as Procter & Gamble, Kimberly-Clark, and Unicharm are making progress in establishing closed-loop recycling of used diapers and converting diaper waste into new diapers. However, the broad potential for possible new products made from diaper waste has yet to be fully exploited. This review focuses on the enormous promise of diaper waste from the perspective of emerging open-loop recycling pathways. We demonstrate that diaper waste can be harnessed and converted into nondiaper products, including energy pellets, anode material for lithium-ion batteries, concrete admixture, catalysts, soil amendment, and mushroom cultivation substrates. We also explore several active, commercial-scale diaper recycling approaches and provide a comprehensive blueprint to encourage open-loop recycling. Open-loop recycling is a practical strategy for managing diaper waste, rectifying environmental damage, and contributing to circular supply chains. Key words: disposable diapers waste, superabsorbent polymer, life cycle assessment, closed-loop recycling, open-loop recycling. Les couches jetables d'aujourd'hui sont devenues un choix indispensable parmi les produits d'hygiene, comme le refle-tent leur consommation mondiale massive et la production de dechets. Les dechets de couches ne sont generalement ni tries ni traites, et aboutissent dans les decharges ou les incinerateurs. L'analyse du cycle de vie montre que les dechets de couches ne sont pas uniquement generes apres l'usage unique, mais qu'ils commencent des le stade de l'acquisition des matieres premieres. Bien que ce qui est fait ne puisse etre defait, les dechets de couches peuvent etre recycles. La valorisation des dechets de couches a ete etudiee en laboratoire et a l'echelle commerciale pendant des annees, avec plus ou moins de succes. Les principaux fabri-cants de couches, tels que Procter & Gamble, Kimberly-Clark et Unicharm, progressent dans la mise en place d'un recyclage en circuit ferme des couches usagees et dans la transformation des dechets de couches en nouvelles couches. Cependant, le large eventail de possibles nouveaux produits faits a partir des dechets de couches n'a pas encore ete pleinement exploite. Cette etude se concentre sur l'enorme promesse offerte par les dechets de couches quant a de nouvelles voies de recyclage en boucle ouverte. Les auteurs demontrent que les dechets de couches ont ete exploites et convertis en produits autres que les couches, notamment en granules energetiques, en anodes pour les accumulateurs lithium-ion, en adjuvants pour beton, en catalyseurs, en amende-ments du sol et en substrats pour la culture des champignons. Ils explorent egalement plusieurs approches actives de recyclage des couches a l'echelle commerciale et fournissent un plan detaille pour encourager le recyclage en boucle ouverte. Le recyclage en boucle ouverte est une strategie pratique pour gerer les dechets de couches, rectifier les dommages environnementaux et con-tribuer aux chalnes d'approvisionnement circulaires. Mots-cles: dechets de couches jetables, polymere superabsorbant, analyse du cycle de vie, recyclage en boucle fermee, recyclage en boucle ouverte., 1. Introduction The invention of single-use disposable diapers has gained worldwide popularity because they offer optimal urine absorption, superior hygiene, and great convenience at a reasonable price, owing to highly [...]

ProteomicsDB (https://www.ProteomicsDB.org) is a multi-omics and multi-organism resource for life science research. In this update, we present our efforts to continuously develop and expand ProteomicsDB. The major focus over the last two years was improving the findability, accessibility, interoperability and reusability (FAIR) of the data as well as its implementation. For this purpose, we release a new application programming interface (API) that provides systematic access to essentially all data in ProteomicsDB. Second, we release a new open-source user interface (UI) and show the advantages the scientific community gains from such software. With the new interface, two new visualizations of protein primary, secondary and tertiary structure as well an updated spectrum viewer were added. Furthermore, we integrated ProteomicsDB with our deep-neural-network Prosit that can predict the fragmentation characteristics and retention time of peptides. The result is an automatic processing pipeline that can be used to reevaluate database search engine results stored in ProteomicsDB. In addition, we extended the data content with experiments investigating different human biology as well as a newly supported organism., (© The Author(s) 2021. Published by Oxford University Press on behalf of Nucleic Acids Research.)