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Bilayer crystals, built by stacking crystalline monolayers, generate interlayer potentials that govern excitonic phenomena but are constrained by fixed covalent lattices and orientations. Replacing one layer with an atomically thin molecular crystal overcomes this limitation, as diverse functional groups enable tunable molecular lattices and interlayer potentials, tailoring a wide range of excitonic properties. Here, we report hybrid excitons in four-atom-thick hybrid bilayer crystals (HBCs), directly synthesized with single-crystalline perylene diimide (PDI) molecular crystal atop WS2 monolayers. These excitons arise from a hybridized bilayer band structure, revealed by lattice-scale first-principles calculations, inheriting properties from both monolayers. They exhibit bright photoluminescence with near-unity polarization above and below the WS2 bandgap, along with spectral signatures of exciton delocalization, supported by theory, while their energies and intensities are tuned by modifying the HBC composition by synthesis. Our work introduces a molecule-based 2D quantum materials platform for bottom-up design and control of optoelectronic properties., Comment: arXiv admin note: text overlap with arXiv:2412.12027

The superconducting order parameter at the KTaO3 interfaces and its dependence on interface orientation remains a subject of debate. The superconductivity at these interfaces exhibits strong resilience against in-plane magnetic field and violates Pauli limit. The interface orientation dependence of critical field and violation of Pauli limit, however, have not been investigated. To address this problem, we grew epitaxial LaMnO3/KTaO3 heterostructures using molecular beam epitaxy. We show that superconductivity is extremely robust against the in-plane magnetic field. Our results indicate that the interface orientation, despite impacting the critical temperature, does not affect the ratio of critical field to the Pauli limiting field. These results offer opportunities to engineer superconductors which are resilient against magnetic field.

Two-dimensional twisted bilayer moir\'e structures provide a versatile material platform for realizing a rich variety of strongly correlated electronic quantum phases intricately coupled with the periodically modulated lattice structures. In this work, we use ultrafast electron diffraction to directly reveal the photoinduced dynamic evolution of the moir\'e superlattice in $2^\circ$ and $57^\circ$ twisted WSe$_2$/MoSe$_2$ heterobilayers. Upon above-band-gap photoexcitation, the moir\'e superlattice diffraction features are enhanced within 1 ps and subsequently suppressed several picoseconds after, accompanied by a collective lattice excitation of a moir\'e phonon mode with sub-THz frequency. This unique response deviates markedly from typical photoinduced lattice heating, and suggests dynamic twisting and untwisting of the local moir\'e chiral structure. We infer large oscillations in the local twist angle, approaching $1^\circ$ peak to trough, that are driven by ultrafast charge carrier excitation and relaxation -- a phenomenon further supported by molecular dynamics simulations. Our findings suggest a novel approach for real-time dynamic reconfiguration of moire superlattices to achieve ultrafast modulation of their strongly correlated behaviors.

Lorentz invariance is a fundamental symmetry of spacetime and foundational to modern physics. One of its most important consequences is the constancy of the speed of light. This invariance, together with the geometry of spacetime, implies that no particle can move faster than the speed of light. In this article, we present the most stringent neutrino-based test of this prediction, using the highest energy neutrino ever detected to date, KM3-230213A. The arrival of this event, with an energy of $220^{+570}_{-110}\,\text{PeV}$, sets a constraint on $\delta \equiv c_\nu^2-1 < 4\times10^{-22}$.

This study investigates the scintillation properties of polycrystalline diamond for particle detection applications, particularly in neutron and alpha radiation environments. Polycrystalline diamonds provide a cost-effective alternative to monocrystalline diamonds while retaining essential detection properties. Photoluminescence measurements were performed to analyze emission spectra, revealing distinct characteristics based on impurity content and crystallinity. Scintillation responses were assessed using Silicon Photomultipliers (SiPMs), demonstrating the capability of polycrystalline diamond powders to respond to alpha irradiation, albeit with reduced resolution compared to traditional scintillators. A prototype neutron detector was developed by combining diamond powder with neutron-sensitive ${}^6$LiF, and its performance was evaluated through experimental testing and Geant4 simulations. The findings indicate that polycrystalline diamond-based detectors can achieve significant detection efficiency while remaining insensitive to gamma radiation, offering potential for portable neutron detection applications.

On February 13th, 2023, the KM3NeT/ARCA telescope detected a neutrino candidate with an estimated energy in the hundreds of PeVs. In this article, the observation of this ultra-high-energy neutrino is discussed in light of null observations above tens of PeV from the IceCube and Pierre Auger observatories. Performing a joint fit of all experiments under the assumption of an isotropic $E^{-2}$ flux, the best-fit single-flavour flux normalisation is $E^2 \Phi^{\rm 1f}_{\nu + \bar \nu} = 7.5 \times 10^{-10}~{\rm GeV cm^{-2} s^{-1} sr^{-1}}$ in the 90% energy range of the KM3NeT event. Furthermore, the ultra-high-energy data are then fit together with the IceCube measurements at lower energies, either with a single power law or with a broken power law, allowing for the presence of a new component in the spectrum. The joint fit including non-observations by other experiments in the ultra-high-energy region shows a slight preference for a break in the PeV regime if the ``High-Energy Starting Events'' sample is included, and no such preference for the other two IceCube samples investigated. A stronger preference for a break appears if only the KM3NeT data is considered in the ultra-high-energy region, though the flux resulting from such a fit would be inconsistent with null observations from IceCube and Pierre Auger. In all cases, the observed tension between KM3NeT and other datasets is of the order of $2.5\sigma-3\sigma$, and increased statistics are required to resolve this apparent tension and better characterise the neutrino landscape at ultra-high energies., Comment: 11 pages, 4 figures

The KM3NeT observatory detected the most energetic neutrino candidate ever observed, with an energy between 72 PeV and 2.6 EeV at the 90% confidence level. The observed neutrino is likely of cosmic origin. In this article, it is investigated if the neutrino could have been produced within the Milky Way. Considering the low fluxes of the Galactic diffuse emission at these energies, the lack of a nearby potential Galactic particle accelerator in the direction of the event and the difficulty to accelerate particles to such high energies in Galactic systems, we conclude that if the event is indeed cosmic, it is most likely of extragalactic origin.

Traveling waves are widely observed in the brain, but their precise computational function remains unclear. One prominent hypothesis is that they enable the transfer and integration of spatial information across neural populations. However, few computational models have explored how traveling waves might be harnessed to perform such integrative processing. Drawing inspiration from the famous ``Can one hear the shape of a drum?'' problem -- which highlights how spectral modes encode geometric information -- we introduce a set of convolutional recurrent neural networks that learn to produce traveling waves in their hidden states in response to visual stimuli. By applying a spectral decomposition to these wave-like activations, we obtain a powerful new representational space that outperforms equivalently local feed-forward networks on tasks requiring global spatial context. In particular, we observe that traveling waves effectively expand the receptive field of locally connected neurons, supporting long-range encoding and communication of information. We demonstrate that models equipped with this mechanism and spectral readouts solve visual semantic segmentation tasks demanding global integration, where local feed-forward models fail. As a first step toward traveling-wave-based representations in artificial networks, our findings suggest potential efficiency benefits and offer a new framework for connecting to biological recordings of neural activity.

Multi-class segmentation of the aorta in computed tomography angiography (CTA) scans is essential for diagnosing and planning complex endovascular treatments for patients with aortic dissections. However, existing methods reduce aortic segmentation to a binary problem, limiting their ability to measure diameters across different branches and zones. Furthermore, no open-source dataset is currently available to support the development of multi-class aortic segmentation methods. To address this gap, we organized the AortaSeg24 MICCAI Challenge, introducing the first dataset of 100 CTA volumes annotated for 23 clinically relevant aortic branches and zones. This dataset was designed to facilitate both model development and validation. The challenge attracted 121 teams worldwide, with participants leveraging state-of-the-art frameworks such as nnU-Net and exploring novel techniques, including cascaded models, data augmentation strategies, and custom loss functions. We evaluated the submitted algorithms using the Dice Similarity Coefficient (DSC) and Normalized Surface Distance (NSD), highlighting the approaches adopted by the top five performing teams. This paper presents the challenge design, dataset details, evaluation metrics, and an in-depth analysis of the top-performing algorithms. The annotated dataset, evaluation code, and implementations of the leading methods are publicly available to support further research. All resources can be accessed at https://aortaseg24.grand-challenge.org.

Controlling the spectral and polarization responses of two-dimensional (2D) crystals is vital for developing ultra-thin platforms for compact optoelectronic devices. However, independently tuning optical anisotropy and spectral response remains challenging in conventional semiconductors due to the intertwined nature of their lattice and electronic structures. Here, we report spectra-orthogonal optical anisotropy, where polarization anisotropy is tuned independently of spectral response, in wafer-scale, one-atom-thick 2D molecular crystal (2DMC) monolayers synthesized on monolayer transition metal dichalcogenide (TMD) crystals. Utilizing the concomitant spectral consistency and structural tunability of perylene derivatives, we demonstrate tunable optical polarization anisotropy in 2DMCs with similar spectral profiles, as confirmed by room-temperature scanning tunneling microscopy and cross-polarized reflectance microscopy. Additional angle-dependent analysis of the single- and polycrystalline molecular domains reveals an epitaxial relationship between the 2DMC and the TMD. Our results establish a scalable, molecule-based 2D crystalline platform for unique and tunable functionalities unattainable in covalent 2D solids.

Oscillations of atmospheric muon and electron neutrinos produce tau neutrinos with energies in the GeV range, which can be observed by the ORCA detector of the KM3NeT neutrino telescope in the Mediterranean Sea. First measurements with ORCA6, an early subarray corresponding to about 5$\%$ of the final detector, are presented. A sample of 5828 neutrino candidates has been selected from the analysed exposure of 433 kton-years. The $\nu_\tau$ normalisation, defined as the ratio between the number of observed and expected tau neutrino events, is measured to be $S_\tau = 0.48^{+0.5}_{-0.33}$. This translates into a $\nu_\tau$ charged-current cross section measurement of $\sigma_{\tau}^{\text{meas}} = (2.5 ^{+2.6}_{-1.8}) \times 10^{-38}$ cm$^{2}$ nucleon$^{-1}$ at the median $\nu_\tau$ energy of 20.3 GeV. The result is consistent with the measurements of other experiments. In addition, the current limit on the non-unitarity parameter affecting the $\tau$-row of the neutrino mixing matrix was improved, with $\alpha_{33}>$ 0.95 at the 95$\%$ confidence level., Comment: 25 pages, 8 figures

Due to the lack of a net magnetic moment, antiferromagnets possess a unique robustness to external magnetic fields and are thus predicted to play an important role in future magnetic technologies. However, this robustness also makes them quite difficult to control, and the development of novel methods to manipulate these systems with external stimuli is a fundamental goal of antiferromagnetic spintronics. In this work, we report evidence for a metastable reorientation of the order parameter in an antiferromagnetic semiconductor triggered by an ultrafast quench of the equilibrium order via photoexcitation above the band gap. The metastable state forms less than 10 ps after the excitation pulse, and persists for longer than 150 ps before decaying to the ground state via thermal fluctuations. Importantly, this transition cannot be induced thermodynamically, and requires the system to be driven out of equilibrium. Broadly speaking, this phenomenology is ultimately the result of large magnetoelastic coupling in combination with a relatively low symmetry of the magnetic ground state. Since neither of these properties are particularly uncommon in magnetic materials, the observations presented here imply a generic path toward novel device technology enabled by ultrafast dynamics in antiferromagnets., Comment: 41 pages, 27 figures

Conversational AI agents are commonly applied within single-user, turn-taking scenarios. The interaction mechanics of these scenarios are trivial: when the user enters a message, the AI agent produces a response. However, the interaction dynamics are more complex within group settings. How should an agent behave in these settings? We report on two experiments aimed at uncovering users' experiences of an AI agent's participation within a group, in the context of group ideation (brainstorming). In the first study, participants benefited from and preferred having the AI agent in the group, but participants disliked when the agent seemed to dominate the conversation and they desired various controls over its interactive behaviors. In the second study, we created functional controls over the agent's behavior, operable by group members, to validate their utility and probe for additional requirements. Integrating our findings across both studies, we developed a taxonomy of controls for when, what, and where a conversational AI agent in a group should respond, who can control its behavior, and how those controls are specified and implemented. Our taxonomy is intended to aid AI creators to think through important considerations in the design of mixed-initiative conversational agents., Comment: 31 pages, 7 figures. In Proceedings of the 30th International Conference on Intelligent User Interfaces (IUI '25), March 24-27, 2025, Cagliari, Italy

GaN has emerged to be a major semiconductor akin to silicon due to its revolutionary impacts in solid state lighting, critically enabled by p-type doping, and high-performance radio-frequency and power electronics. Suffering from inefficient hole doping and low hole mobility, quantum oscillations in p-type GaN have not been observed, hindering fundamental studies of valence bands and hole transport in GaN. Here, we present the first observation of quantum oscillations of holes in GaN. Shubnikov-de Haas (SdH) oscillations in hole resistivity are observed in a quantum-confined two-dimensional hole gas at a GaN/AlN interface, where polarization-induced doping overcomes thermal freeze-out, and a sharp and clean interface boosts the hole mobility enough to unmask the quantum oscillations. These holes degenerately occupy the light and heavy hole bands of GaN and have record-high mobilities of ~1900 cm2/Vs and ~400 cm2/Vs at 3K, respectively. We use magnetic fields up to 72 T to resolve SdH oscillations of holes from both valence bands to extract their respective sheet densities, quantum scattering times, and the effective masses of light holes (0.5-0.7 m0) and heavy holes (1.9 m0). SdH oscillations of heavy and light holes in GaN constitute a direct metrology of valence bands and open new venues for quantum engineering in this technologically important semiconductor. Like strained silicon transistors, strain-engineering of the valence bands of GaN is predicted to dramatically improve hole mobilities by reducing the hole effective mass, a proposal that can now be explored experimentally, particularly in a fully fabricated transistor, using quantum oscillations. Furthermore, the findings of this work suggest a blueprint to create 2D hole gases and observe quantum oscillations of holes in related wide bandgap semiconductors such as SiC and ZnO in which such techniques are not yet possible.

Studying the interstellar medium in nearby starbursts is essential for understanding the physical mechanisms driving these objects, thought to resemble young star-forming galaxies. This study aims to analyze the physical properties of the first spatially-resolved multi-wavelength SED of an extragalactic source, spanning six decades in frequency (from near-UV to cm wavelengths) at an angular resolution of 3$^{\prime\prime}$ (51 pc at the distance of NGC,253). We focus on the central molecular zone (CMZ) of NGC,253, which contains giant molecular clouds (GMCs) responsible for half of the galaxy's star formation. We use archival data, spanning optical to centimeter wavelengths, to compute SEDs with the GalaPy and CIGALE codes for validation, and analyze stellar optical spectra with the \textsc{starlight} code. Our results show significant differences between central and external GMCs in terms of stellar and dust masses, star formation rates (SFRs), and bolometric luminosities. We identify the best SFR tracers as radio continuum bands at 33 GHz, radio recombination lines, and the total infrared luminosity (L$_{\rm IR}$; 8-1000$\mu$m), as well as 60$\mu$m IR emission. BPT and WHAN diagrams indicate shock signatures in NGC~253's nuclear region, associating it with AGN/star-forming hybrids, though the AGN fraction is negligible ($\leq$7.5%). Our findings show significant heterogeneity in the CMZ, with central GMCs exhibiting higher densities, SFRs, and dust masses compared to external GMCs. We confirm that certain centimeter photometric bands can reliably estimate global SFR at GMC scales., Comment: Submitted to A&A. 33 pages (20 main text), 20 figures (13 main text)

In the era of precision measurements of neutrino oscillation parameters, it is necessary for experiments to disentangle discrepancies that may indicate physics beyond the Standard Model in the neutrino sector. KM3NeT/ORCA is a water Cherenkov neutrino detector under construction and anchored at the bottom of the Mediterranean Sea. The detector is designed to study the oscillations of atmospheric neutrinos and determine the neutrino mass ordering. This paper focuses on the initial configuration of ORCA, referred to as ORCA6, which comprises six out of the foreseen 115 detection units of photosensors. A high-purity neutrino sample was extracted during 2020 and 2021, corresponding to an exposure of 433 kton-years. This sample is analysed following a binned log-likelihood approach to search for invisible neutrino decay, in a three-flavour neutrino oscillation scenario, where the third neutrino mass state $\nu_3$ decays into an invisible state, e.g. a sterile neutrino. The resulting best fit of the invisible neutrino decay parameter is $\alpha_3 = 0.92^{+1.08}_{-0.57}\times 10^{-4}~\mathrm{eV^2}$, corresponding to a scenario with $\theta_{23}$ in the second octant and normal neutrino mass ordering. The results are consistent with the Standard Model, within a $2.1\,\sigma$ interval., Comment: 20 pages, 8 figures

Integrating the ATLAS/BNL VMM3a ASIC (Application Specific Integrated Circuit) into the RD51/SRS (Scalable Readout System) provides a self-triggered continuous readout system for various gaseous detectors. Since the system allows flexible parameters, such as switching the polarity, adjusting electronics gain or different peaking times, the settings can be adjusted for a wide range of detectors. The system allows particles to be recorded with a MHz interaction rate in energy, space, and time. The system will be introduced in the beginning, and short examples will be given for different applications. After, the Twin GEM TPC will be discussed in more detail to show the benefits of such a trigger-less system in combination with the Twin configuration. Last, a few results for the tracking performance and the possibility to operate as a tracking telescope will be shown. Thus, this presents the possibility of an extremely low material budget tracking system suitable for tracking from high to low-energy particle beams.

The Gaseous Electron Multiplier-based Time Projection Chamber (GEM-TPC) in TWIN configuration for particle tracking has been consolidated after extensive investigations in different facilities to study its tracking performance. The most attractive feature of this detector is its ultra-low material budget, which is 0.28\% X/X$_0$ and can be further reduced by decreasing the thickness of the gas traversed by the incident particles. Thus, it provides excellent position reconstruction and reduced multi-scattering. This detector consists of two GEM-TPCs with drift fields in opposite directions, achieved by rotating one 180 degrees in the middle plane with respect to the other. These two GEM-TPCs share the same gas volume, i.e., inside a single vessel. This configuration is called a TWIN configuration. The results presented in this work were measured using the newly integrated VMM3a/SRS readout electronics, an important milestone in improving overall performance and capabilities. In 2024, this detector was tested at the H4 beamline of the SPS at CERN, using muons and pions and with different gas mixtures like, for instance: Ar/CO$_2$ (70/30 \%), He/CO$_2$ (70/30 \%) and He/CO$_2$ (90/10 \%). The helium-based mixtures were used to commission the detector to track low momenta muons required in the PSI muon-induced X-ray emission (MIXE) experiment. The results obtained from these measurements, a brief discussion of the methodology used for the data analysis, and a comparison of the spatial resolution for different gas mixtures will be presented., Comment: 5 pages, 5 figures

The discovery of superconductivity under high pressure in Ruddlesden-Popper phases of bulk nickelates has sparked great interest in stabilizing ambient pressure superconductivity in thin-film form using epitaxial strain. Recently, signs of superconductivity have been observed in compressively strained bilayer nickelate thin films with an onset temperature exceeding 40 K, albeit with broad and two-step-like transitions. Here, we report intrinsic superconductivity and normal-state transport properties in compressively strained La$_2$PrNi$_2$O$_7$ thin films, achieved through a combination of isovalent Pr substitution, growth optimization, and precision ozone annealing. The superconducting onset occurs above 48 K, with zero resistance reached above 30 K, and the critical current density at 1.4 K is 100-fold larger than previous reports. The normal-state resistivity exhibits quadratic temperature dependence indicative of Fermi liquid behaviour, and other phenomenological similarities to transport in overdoped cuprates suggest parallels in their emergent properties., Comment: 18 pages, 4 figures

The discovery of high-temperature superconductivity in bulk La$_3$Ni$_2$O$_7$ under high hydrostatic pressure and, more recently, biaxial compression in epitaxial thin films has ignited significant interest in understanding the interplay between atomic and electronic structure in these compounds. Subtle changes in the nickel-oxygen bonding environment are thought to be key drivers for stabilizing superconductivity, but specific details of which bonds and which modifications are most relevant remains so far unresolved. While direct, atomic-scale structural characterization under hydrostatic pressure is beyond current experimental capabilities, static stabilization of strained La$_3$Ni$_2$O$_7$ films provides a platform well-suited to investigation with new picometer-resolution electron microscopy methods. Here, we use multislice electron ptychography to directly measure the atomic-scale structural evolution of La$_3$Ni$_2$O$_7$ thin films across a wide range of biaxial strains tuned via substrate. By resolving both the cation and oxygen sublattices, we study strain-dependent evolution of atomic bonds, providing the opportunity to isolate and disentangle the effects of specific structural motifs for stabilizing superconductivity. We identify the lifting of crystalline symmetry through modification of the nickel-oxygen octahedral distortions under compressive strain as a key structural ingredient for superconductivity. Rather than previously supposed $c$-axis compression, our results highlight the importance of in-plane biaxial compression in superconducting thin films, which suggests an alternative -- possibly cuprate-like -- understanding of the electronic structure. Identifying local regions of inhomogeneous oxygen stoichiometry and high internal strain near crystalline defects, we suggest potential pathways for improving the sharpness and temperature of the superconducting transition., Comment: 4 figures, 3 tables, 15 supplemental figures

PICOSEC Micromegas (MM) is a precise timing gaseous detector based on a Cherenkov radiator coupled with a semi-transparent photocathode and an MM amplifying structure. The detector conceprt was successfully demonstrated through a single-channel prototype, achieving sub-25 ps time resolution with Minimum Ionizing Particles (MIPs). A series of studies followed, aimed at developing robust, large-area, and scalable detectors with high time resolution, complemented by specialized fast-response readout electronics. This work presents recent advancements towards large-area resistive PICOSEC MM, including 10 $\times$ 10 $\text{cm}^2$ area prototypes and a 20 $\times$ 20 $\text{cm}^2$ prototype, which features the jointing of four photocathodes. The time resolution of these detector prototypes was tested during the test beam, achieved a timing performance of around 25 ps for individual pads in MIPs. Meanwhile, customized electronics have been developed dedicated to the high-precision time measurement of the large-area PICOSEC MM. The performance of the entire system was evaluated during the test beam, demonstrating its capability for large-area integration. These advancements highlight the potential of PICOSEC MM to meet the stringent requirements of future particle physics experiments.

Precise alignment of the electron beam is critical for successful application of scanning transmission electron microscopes (STEM) to understanding materials at atomic level. Despite the success of aberration correctors, aberration correction is still a complex process. Here we approach aberration correction from the perspective of accelerator physics and show it is equivalent to minimizing the emittance growth of the beam, the span of the phase space distribution of the probe. We train a deep learning model to predict emittance growth from experimentally accessible Ronchigrams. Both simulation and experimental results show the model can capture the emittance variation with aberration coefficients accurately. We further demonstrate the model can act as a fast-executing function for the global optimization of the lens parameters. Our approach enables new ways to quickly quantify and automate aberration correction that takes advantage of the rapid measurements possible with high-speed electron cameras. In part II of the paper, we demonstrate how the emittance metric enables rapid online tuning of the aberration corrector using Bayesian optimization., Comment: 27 pages, 6 figures

Aberration-corrected Scanning Transmission Electron Microscopy (STEM) has become an essential tool in understanding materials at the atomic scale. However, tuning the aberration corrector to produce a sub-{\AA}ngstr\"om probe is a complex and time-costly procedure, largely due to the difficulty of precisely measuring the optical state of the system. When measurements are both costly and noisy, Bayesian methods provide rapid and efficient optimization. To this end, we develop a Bayesian approach to fully automate the process by minimizing a new quality metric, beam emittance, which is shown to be equivalent to performing aberration correction. In part I, we derived several important properties of the beam emittance metric and trained a deep neural network to predict beam emittance growth from a single Ronchigram. Here we use this as the black box function for Bayesian Optimization and demonstrate automated tuning of simulated and real electron microscopes. We explore different surrogate functions for the Bayesian optimizer and implement a deep neural network kernel to effectively learn the interactions between different control channels without the need to explicitly measure a full set of aberration coefficients. Both simulation and experimental results show the proposed method outperforms conventional approaches by achieving a better optical state with a higher convergence rate., Comment: 24 pages, 12 figures

Combining gaseous detectors with a high-granularity pixelated charge readout enables experimental applications which otherwise could not be achieved. This includes high-resolution tracking of low-energetic particles, requiring ultra-low material budget, X-ray polarimetry at low energies ($\lessapprox$ 2 keV) or rare-event searches which profit from event selection based on geometrical parameters. In this article, the idea of embedding a pixel ASIC - specifically the Timepix4 - into a micro-pattern gaseous amplification stage is illustrated. Furthermore, the first results of reading out a triple-GEM detector with the Timepix4 (GEMPix4) are shown, including the first X-ray images taken with a Timepix4 utilising Through Silicon Vias (TSVs). Lastly, a new readout concept is presented, called the 'Silicon Readout Board', extending the use of pixel ASICs to read out gaseous detectors to a wider range of HEP applications.

Sliced inverse regression (SIR) is a popular sufficient dimension reduction method that identifies a few linear transformations of the covariates without losing regression information with the response. In high-dimensional settings, SIR can be combined with sparsity penalties to achieve sufficient dimension reduction and variable selection simultaneously. Nevertheless, both classical and sparse estimators assume the covariates are exogenous. However, endogeneity can arise in a variety of situations, such as when variables are omitted or are measured with error. In this article, we show such endogeneity invalidates SIR estimators, leading to inconsistent estimation of the true central subspace. To address this challenge, we propose a two-stage Lasso SIR estimator, which first constructs a sparse high-dimensional instrumental variables model to obtain fitted values of the covariates spanned by the instruments, and then applies SIR augmented with a Lasso penalty on these fitted values. We establish theoretical bounds for the estimation and selection consistency of the true central subspace for the proposed estimators, allowing the number of covariates and instruments to grow exponentially with the sample size. Simulation studies and applications to two real-world datasets in nutrition and genetics illustrate the superior empirical performance of the two-stage Lasso SIR estimator compared with existing methods that disregard endogeneity and/or nonlinearity in the outcome model., Comment: 63 pages

In this study, we explore the characteristics of `low-mass' ($\log(M_{\star}/M_{\odot}) \leq 8$) and `intermediate-mass' ($8 \lt \log(M_{\star}/M_{\odot}) \leq 10$) host galaxies of Type Ia supernovae (SNe Ia) from the second data release (DR2) of the Zwicky Transient Facility survey and investigate their correlations with different sub-types of SNe Ia. We use the photospheric velocities measured from the Si II $\lambda$6355 feature, SALT2 light-curve stretch ($x_1$) and host-galaxy properties of SNe Ia to re-investigate the existing relationship between host galaxy mass and Si II $\lambda$6355 velocities. We also investigate sub-type preferences for host populations and show that while the more energetic and brighter 91T-like SNe Ia tends to populate the younger host populations, 91bg-like SNe Ia populate in the older populations. Our findings suggest High Velocity SNe Ia (HV SNe Ia) not only comes from the older populations but they also come from young populations as well. Therefore, while our findings can partially provide support for HV SNe Ia relating to single degenerate progenitor models, they indicate that HV SNe Ia other than being a different population, might be a continued distribution with different explosion mechanisms. We lastly investigate the specific rate of SNe Ia in the volume-limited SN Ia sample of DR2 and compare with other surveys., Comment: 13 pages, 8 figures, accepted for publication in Astronomy & Astrophysics

Visual odometry (VO) aims to estimate camera poses from visual inputs -- a fundamental building block for many applications such as VR/AR and robotics. This work focuses on monocular RGB VO where the input is a monocular RGB video without IMU or 3D sensors. Existing approaches lack robustness under this challenging scenario and fail to generalize to unseen data (especially outdoors); they also cannot recover metric-scale poses. We propose Robust Metric Visual Odometry (RoMeO), a novel method that resolves these issues leveraging priors from pre-trained depth models. RoMeO incorporates both monocular metric depth and multi-view stereo (MVS) models to recover metric-scale, simplify correspondence search, provide better initialization and regularize optimization. Effective strategies are proposed to inject noise during training and adaptively filter noisy depth priors, which ensure the robustness of RoMeO on in-the-wild data. As shown in Fig.1, RoMeO advances the state-of-the-art (SOTA) by a large margin across 6 diverse datasets covering both indoor and outdoor scenes. Compared to the current SOTA DPVO, RoMeO reduces the relative (align the trajectory scale with GT) and absolute trajectory errors both by >50%. The performance gain also transfers to the full SLAM pipeline (with global BA & loop closure). Code will be released upon acceptance.

The first partial boundary data complex geometrical optics based methods for electrical impedance tomography in three dimensions are developed, and tested, on simulated and experimental data. The methods provide good localization of targets for both absolute and time-difference imaging, when large portions of the domain are inaccessible for measurement. As most medical applications of electrical impedance tomography are limited to partial boundary data, the development of partial boundary algorithms is highly desirable. While iterative schemes have been used traditionally, their high computational cost makes them cost-prohibitive for applications that need fast imaging. The proposed algorithms require no iteration and provide informative absolute or time-difference images exceptionally quickly in under 2 seconds. Reconstructions are compared to reference reconstructions from standard linear difference imaging (30 seconds) and total variation regularized absolute imaging (several minutes) The algorithms perform well under high levels of noise and incorrect domain modeling., Comment: 10 pages, 9 figures, 1 table

We introduce the Byte Latent Transformer (BLT), a new byte-level LLM architecture that, for the first time, matches tokenization-based LLM performance at scale with significant improvements in inference efficiency and robustness. BLT encodes bytes into dynamically sized patches, which serve as the primary units of computation. Patches are segmented based on the entropy of the next byte, allocating more compute and model capacity where increased data complexity demands it. We present the first FLOP controlled scaling study of byte-level models up to 8B parameters and 4T training bytes. Our results demonstrate the feasibility of scaling models trained on raw bytes without a fixed vocabulary. Both training and inference efficiency improve due to dynamically selecting long patches when data is predictable, along with qualitative improvements on reasoning and long tail generalization. Overall, for fixed inference costs, BLT shows significantly better scaling than tokenization-based models, by simultaneously growing both patch and model size.

AI assistants are being created to help software engineers conduct a variety of coding-related tasks, such as writing, documenting, and testing code. We describe the use of the watsonx Code Assistant (WCA), an LLM-powered coding assistant deployed internally within IBM. Through surveys of two user cohorts (N=669) and unmoderated usability testing (N=15), we examined developers' experiences with WCA and its impact on their productivity. We learned about their motivations for using (or not using) WCA, we examined their expectations of its speed and quality, and we identified new considerations regarding ownership of and responsibility for generated code. Our case study characterizes the impact of an LLM-powered assistant on developers' perceptions of productivity and it shows that although such tools do often provide net productivity increases, these benefits may not always be experienced by all users., Comment: 21 pages, 3 figures. To be published in CHI EA 2025

Recent advances in neural recording technology allow simultaneously recording action potentials from hundreds to thousands of neurons in awake, behaving animals. However, characterizing spike patterns in the resulting data, and linking these patterns to behaviour, remains a challenging task. The lack of a rigorous mathematical language for variable numbers of events (spikes) emitted by multiple agents (neurons) is an important limiting factor. We introduce a new mathematical operation to decompose complex spike patterns into a set of simple, structured elements. This creates a mathematical language that allows comparing spike patterns across trials, detecting sub-patterns, and making links to behaviour via a clear distance measure. We apply the method to dual Utah array recordings from macaque prefrontal cortex, where this technique reveals previously unseen structure that can predict both memory-guided decisions and errors in a virtual-reality working memory task. These results demonstrate that this technique provides a powerful new approach to understand structure in the spike times of neural populations, at a scale that will continue to grow more and more rapidly in upcoming years.

KM3NeT/ORCA is an underwater neutrino telescope under construction in the Mediterranean Sea. Its primary scientific goal is to measure the atmospheric neutrino oscillation parameters and to determine the neutrino mass ordering. ORCA can constrain the oscillation parameters $\Delta m^{2}_{31}$ and $\theta_{23}$ by reconstructing the arrival direction and energy of multi-GeV neutrinos crossing the Earth. Searches for deviations from the Standard Model of particle physics in the forward scattering of neutrinos inside Earth matter, produced by Non-Standard Interactions, can be conducted by investigating distortions of the standard oscillation pattern of neutrinos of all flavours. This work reports on the results of the search for non-standard neutrino interactions using the first six detection units of ORCA and 433 kton-years of exposure. No significant deviation from standard interactions was found in a sample of 5828 events reconstructed in the 1 GeV$-$1 TeV energy range. The flavour structure of the non-standard coupling was constrained at 90\% confidence level to be $|\varepsilon_{\mu\tau} | \leq 5.4 \times 10^{-3}$, $|\varepsilon_{e\tau} | \leq 7.4 \times 10^{-2}$, $|\varepsilon_{e\mu} | \leq 5.6 \times 10^{-2}$ and $-0.015 \leq \varepsilon_{\tau\tau} - \varepsilon_{\mu\mu} \leq 0.017$. The results are comparable to the current most stringent limits placed on the parameters by other experiments.

When fitting generalized linear mixed models (GLMMs), one important decision to make relates to the choice of the random effects distribution. As the random effects are unobserved, misspecification of this distribution is a real possibility. In this article, we investigate the consequences of random effects misspecification for point prediction and prediction inference in GLMMs, a topic on which there is considerably less research compared to consequences for parameter estimation and inference. We use theory, simulation, and a real application to explore the effect of using the common normality assumption for the random effects distribution when the correct specification is a mixture of normal distributions, focusing on the impacts on point prediction, mean squared prediction errors (MSEPs), and prediction intervals. We found that the optimal shrinkage is different under the two random effect distributions, so is impacted by misspecification. The unconditional MSEPs for the random effects are almost always larger under the misspecified normal random effects distribution, especially when cluster sizes are small. Results for the MSEPs conditional on the random effects are more complicated, but they remain generally larger under the misspecified distribution when the true random effect is close to the mean of one of the component distributions in the true mixture distribution. Results for prediction intervals indicate that overall coverage probability is not greatly impacted by misspecification.

We investigate the internal and external mechanisms that regulate and quench star formation (SF) in galaxies at $z \sim 0.3$ using MAGPI observations and the EAGLE, Magneticum, and IllustrisTNG cosmological simulations. Using SimSpin to generate mock observations of simulated galaxies, we match detection/resolution limits in star formation rates and stellar mass, along with MAGPI observational details including the average point spread function and pixel scale. While we find a good agreement in the slope of the global star-forming main sequence (SFMS) between MAGPI observations and all three simulations, the slope of the resolved SFMS does not agree within 1 $-$ 2$\sigma$. Furthermore, in radial SF trends, good agreement between observations and simulations exists only for galaxies far below the SFMS, where we capture evidence for inside-out quenching. The simulations overall agree with each other between $\sim1.5-4 \ R_{\rm e}$ but show varying central suppression within $R \sim 1.5 \ R_{\rm e}$ for galaxies on and below the SFMS, attributable to different AGN feedback prescriptions. All three simulations show similar dependencies of SF radial trends with environment. Central galaxies are subject to both internal and external mechanisms, showing increased SF suppression in the centre with increasing halo mass, indicating AGN feedback. Satellite galaxies display increasing suppression in the outskirts as halo mass increases, indicative of environmental processes. These results demonstrate the power of spatially resolved studies of galaxies; while global properties align, radial profiles reveal discrepancies between observations and simulations and their underlying physics., Comment: 20 pages, 10 figures, submitted to MNRAS

A molecular MCB junction in the partially wet phase has been used to probe effects related to open quantum systems. Although the exact quantum system, environment, and coupling, are not known the nature of the experiments shows a measurement influenced next measurement. The quantum system senses the measurement outcome and prepares itself in a state other than the state related to the measurement outcome. This triggers an alternation of measurements which are indicative of two current carrying states. In case three or more current carrying states are observed, there exists a fixed sequence of states that carry the current. We conclude that memory effects in these systems are responsible for these experimental observations.

We introduce TPCNet, a neural network predictor that combines Convolutional and Transformer architectures with Positional encodings, for neutral atomic hydrogen (HI) spectral analysis. Trained on synthetic datasets, our models predict cold neutral gas fraction ($f_\text{CNM}$) and HI opacity correction factor ($R_\text{HI}$) from emission spectra based on the learned relationships between the desired output parameters and observables (optically-thin column density and peak brightness). As a follow-up to Murray et al. (2020)'s shallow Convolutional Neural Network (CNN), we construct deep CNN models and compare them to TPCNet models. TPCNet outperforms deep CNNs, achieving a 10% average increase in testing accuracy, algorithmic (training) stability, and convergence speed. Our findings highlight the robustness of the proposed model with sinusoidal positional encoding applied directly to the spectral input, addressing perturbations in training dataset shuffling and convolutional network weight initializations. Higher spectral resolutions with increased spectral channels offer advantages, albeit with increased training time. Diverse synthetic datasets enhance model performance and generalization, as demonstrated by producing $f_\text{CNM}$ and $R_\text{HI}$ values consistent with evaluation ground truths. Applications of TPCNet to observed emission data reveal strong agreement between the predictions and Gaussian decomposition-based estimates (from emission and absorption surveys), emphasizing its potential in HI spectral analysis., Comment: This paper has 27 pages, 27 figures and two tables. The work has been accepted for publication in Monthly Notices of the Royal Astronomical Society Main Journal

The second data release of Type Ia supernovae (SNe Ia) observed by the Zwicky Transient Facility has provided a homogeneous sample of 3628 SNe Ia with photometric and spectral information. This unprecedented sample size enables us to better explore our currently tentative understanding of the dependence of host environment on SN Ia properties. In this paper, we make use of two-dimensional image decomposition to model the host galaxies of SNe Ia. We model elliptical galaxies as well as disk/spiral galaxies with or without central bulges and bars. This allows for the categorisation of SN Ia based on their morphological host environment, as well as the extraction of intrinsic galaxy properties corrected for both cosmological and atmospheric effects. We find that although this image decomposition technique leads to a significant bias towards elliptical galaxies in our final sample of galaxies, the overall results are robust. By successfully modelling 728 host galaxies, we find that the photometric properties of SNe Ia found in disks and in elliptical galaxies, correlate fundamentally differently with their host environment. We identified strong linear relations between light-curve stretch and our model-derived galaxy colour for both the elliptical (16.8$\sigma$) and disk (5.1$\sigma$) subpopulations of SNe Ia. Lower stretch SNe Ia are found in redder environments, which we identify as an age/metallicity effect. Within the subpopulation of SNe Ia found in disk containing galaxies, we find a significant linear trend (6.1$\sigma$) between light-curve stretch and model-derived local $r$-band surface brightness, which we link to the age/metallicity gradients found in disk galaxies. SN Ia colour shows little correlation with host environment as seen in the literature. We identify a possible dust effect in our model-derived surface brightness (3.3$\sigma$), for SNe Ia in disk galaxies., Comment: ZTF SN Ia DR2 release paper. Submitted to A&A (ZTF DR2 Special Issue)

Indirect dark matter detection methods are used to observe the products of dark matter annihilations or decays originating from astrophysical objects where large amounts of dark matter are thought to accumulate. With neutrino telescopes, an excess of neutrinos is searched for in nearby dark matter reservoirs, such as the Sun and the Galactic Centre, which could potentially produce a sizeable flux of Standard Model particles. The KM3NeT infrastructure, currently under construction, comprises the ARCA and ORCA undersea \v{C}erenkov neutrino detectors located at two different sites in the Mediterranean Sea, offshore of Italy and France, respectively. The two detector configurations are optimised for the detection of neutrinos of different energies, enabling the search for dark matter particles with masses ranging from a few GeV/c$^2$ to hundreds of TeV/c$^2$. In this work, searches for dark matter annihilations in the Galactic Centre and the Sun with data samples taken with the first configurations of both detectors are presented. No significant excess over the expected background was found in either of the two analyses. Limits on the velocity-averaged self-annihilation cross section of dark matter particles are computed for five different primary annihilation channels in the Galactic Centre. For the Sun, limits on the spin-dependent and spin-independent scattering cross sections of dark matter with nucleons are given for three annihilation channels.

Stability selection is a widely adopted resampling-based framework for high-dimensional structure estimation and variable selection. However, the concept of 'stability' is often narrowly addressed, primarily through examining selection frequencies, or 'stability paths'. This paper seeks to broaden the use of an established stability estimator to evaluate the overall stability of the stability selection framework, moving beyond single-variable analysis. We suggest that the stability estimator offers two advantages: it can serve as a reference to reflect the robustness of the outcomes obtained and help identify an optimal regularization value to improve stability. By determining this value, we aim to calibrate key stability selection parameters, namely, the decision threshold and the expected number of falsely selected variables, within established theoretical bounds. Furthermore, we explore a novel selection criterion based on this regularization value. With the asymptotic distribution of the stability estimator previously established, convergence to true stability is ensured, allowing us to observe stability trends over successive sub-samples. This approach sheds light on the required number of sub-samples addressing a notable gap in prior studies. The 'stabplot' package is developed to facilitate the use of the plots featured in this manuscript, supporting their integration into further statistical analysis and research workflows.

We show that the monodromoy group of Nikulin-type orbifolds is maximal and classify finite order symplectic automorphisms up to deformation in terms of their action on the second integral cohomology group.

It is essential to examine the physical or chemical properties of molecular gas in starburst galaxies to reveal the underlying mechanisms characterizing starbursts. We used non-negative matrix factorization (NMF) to extract individual molecular or physical components involved in the star formation process in NGC\,253. We used images of 148 transitions from 44 different species of the ALMA large program ALCHEMI. Additionally, we included the continuum images at ALMA Bands 3 and 7 from the same dataset. For the five NMF components (NF1--5), we obtained that their distributions correspond to various basic phenomena related to star formation: i) low-density gas extended through the galactic central molecular zone (NF2), ii) shocks (NF3), iii) starburst regions (NF4), and iv) young star-forming regions (NF5). The other component (NF1) is related to excitation; three components obtained by NMF (NF3, 1, and 5) show a strong dependence upon the upper state energies of transitions, and represent low-, intermediate-, and high-excitation, respectively. We also compared our results using principal component analysis (PCA) previously applied to the same dataset. Molecular components extracted from NMF are similar to the ones obtained from PCA. However, NMF is better at extracting components associated with a single physical component, while a single component in PCA usually contains information on multiple physical components. This is especially true for features with weak intensities like emission from outflows. Our results suggest that NMF can be one of promising methods interpreting molecular line survey data, especially in the upcoming era of wide-band receivers., Comment: 22 pages, 19 figures, 2 tables. accepted for Publication of the Astronomical Society of Japan. Author's original version

The rapid evolution of software libraries presents a significant challenge for code generation models, which must adapt to frequent version updates while maintaining compatibility with previous versions. Existing code completion benchmarks often overlook this dynamic aspect, and the one that does consider it relies on static code prediction tasks without execution-based evaluation, offering a limited perspective on a model's practical usability. To address this gap, we introduce \textbf{\GitChameleon{}}, a novel, manually curated dataset comprising 116 Python code completion problems, each conditioned on specific library versions and accompanied by executable unit tests. \GitChameleon{} is designed to rigorously assess the ability of modern large language models (LLMs) to generate version-specific code that is not only syntactically correct but also functionally accurate upon execution. Our comprehensive evaluations reveal that state-of-the-art LLMs struggle with this task; for instance, \textbf{GPT-4o} achieves a pass@10 of only 39.9\% (43.7\% when provided with error feedback), highlighting the complexity of the problem and the limitations of current models. By providing an execution-based benchmark that emphasizes the dynamic nature of code libraries, \GitChameleon{} serves as a critical tool to advance the development of more adaptable and reliable code generation models. For facilitation for further exploration of version-conditioned code generation, we make our code repository publicly accessible at \url{https://github.com/NizarIslah/GitChameleon}.

The KM3NeT Collaboration has tackled a common challenge faced by the astroparticle physics community, namely adapting the experiment-specific simulation software to work with the CORSIKA air shower simulation output. The proposed solution is an extension of the open-source code gSeaGen, allowing for the transport of muons generated by CORSIKA to a detector of any size at an arbitrary depth. The gSeaGen code was not only extended in terms of functionalities but also underwent a thorough redesign of the muon propagation routine, resulting in a more accurate and efficient simulation. This paper presents the capabilities of the new gSeaGen code as well as prospects for further developments., Comment: 27 pages, 13 figures, submitted to Computer Physics Communications

The PICOSEC-Micromegas (PICOSEC-MM) detector is a novel gaseous detector designed for precise timing resolution in experimental measurements. It eliminates time jitter from charged particles in ionization gaps by using extreme UV Cherenkov light emitted in a crystal, detected by a Micromegas photodetector with an appropriate photocathode. The first single-channel prototype tested in 150 GeV/c muon beams achieved a timing resolution below 25 ps, a significant improvement compared to standard Micropattern Gaseous Detectors (MPGDs). This work explores the specifications for applying these detectors in monitored neutrino beams for the ENUBET Project. Key aspects include exploring resistive technologies, resilient photocathodes, and scalable electronics. New 7-pad resistive detectors are designed to handle the particle flux. In this paper, two potential scenarios are briefly considered: tagging electromagnetic showers with a timing resolution below 30 ps in an electromagnetic calorimeter as well as individual particles (mainly muons) with about 20 ps respectively.

Stability selection is a versatile framework for structure estimation and variable selection in high-dimensional setting, primarily grounded in frequentist principles. In this paper, we propose an enhanced methodology that integrates Bayesian analysis to refine the inference of inclusion probabilities within the stability selection framework. Traditional approaches rely on selection frequencies for decision-making, often disregarding domain-specific knowledge and failing to account for the inherent uncertainty in the variable selection process. Our methodology uses prior information to derive posterior distributions of inclusion probabilities, thereby improving both inference and decision-making. We present a two-step process for engaging with domain experts, enabling statisticians to elucidate prior distributions informed by expert knowledge while allowing experts to control the weight of their input on the final results. Using posterior distributions, we offer Bayesian credible intervals to quantify uncertainty in the variable selection process. In addition, we highlight how selection frequencies can be uninformative or even misleading when covariates are correlated with each other, and demonstrate how domain expertise can alleviate such issues. Our approach preserves the versatility of stability selection and is suitable for a broad range of structure estimation challenges.

Antiterminators are essential components of bacterial transcriptional regulation, allowing the control of gene expression in response to fluctuating environmental conditions. RNA-binding antiterminators are particularly important regulatory proteins that play a significant role in preventing transcription termination by binding to specific RNA sequences. These RNA-binding antiterminators have been extensively studied for their roles in regulating various metabolic pathways. However, their role in modulating the physiology of pathogens requires further investigations. This review focuses on these RNA-binding proteins in both Gram-positive and Gram-negative bacteria, particularly on their structures, mechanism of action, and target genes. Additionally, the involvement of the antitermination mechanisms in bacterial pathogenicity will be discussed. This knowledge is crucial for understanding the regulatory mechanisms that govern bacterial pathogenicity, opening up exciting prospects for future research, and potentially new alternative strategies to fight against infectious diseases., Comment: arXiv admin comment: This version has been removed by arXiv administrators as the submitter did not have the rights to agree to the license at the time of submission

The growing use of naturalistic stimuli, such as feature films, brings research on emotions closer to ecologically valid settings within brain scanners, such as functional magnetic resonance imaging (fMRI). Music is another cultural artifact known to evoke emotions, and film soundtracks are often designed to enhance the emotional impact of the narrative. However, the neural basis of shared emotional perception during movie-watching, and its relationship to the soundtrack, remains unclear. In this study, participants watched Forrest Gump in a 3T fMRI scanner. The reported shared arousal and valence (positive and negative) was correlated with the spectrogram and tempo information extracted from the soundtrack. For neuroimaging, four regions of interest (ROIs) related to audiovisual input and narrative content were examined: the superior temporal sulcus (STS), amygdala, inferior frontal gyrus, and precuneus. Results: Strong correlations between spectral and tempo, and emotional features (Bonferroni corr). BOLD responses associated with shared positive and negative valence and high-arousal moments were compared to film events with low emotional agreement. Significant activations were found in the STS and precuneus (pFWE < 0.05 peak level). No significant responses were observed in the amygdala or inferior frontal gyrus, but whole-brain analysis (pFWE < 0.05 cluster extent) revealed frontal activity linked to negative valence, alongside expected occipito-temporal lobe responses to the audiovisual stimuli. The STS and precuneus were particularly active during shared emotional perception of valenced and high-arousal events, with the precuneus encoding valence from auditory information. Naturalistic stimuli show promise as diagnostic and therapeutic tools for emotion regulation deficits although challenges may arise when crafting an experimental control.