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47 results on '"Muñoz Torrico, Marcela"'

2. Delamanid-containing regimens and multidrug-resistant tuberculosis: A systematic review and meta-analysis

Author

Nasiri, Mohammad Javad, Zangiabadian, Moein, Arabpour, Erfan, Amini, Sirus, Khalili, Farima, Centis, Rosella, D'Ambrosio, Lia, Denholm, Justin T., Schaaf, H. Simon, van den Boom, Martin, Kurhasani, Xhevat, Dalcolmo, Margareth Pretti, Al-Abri, Seif, Chakaya, Jeremiah, Alffenaar, Jan-Willem, Akkerman, Onno, Silva, Denise Rossato, Muňoz-Torrico, Marcela, Seaworth, Barbara, Pontali, Emanuele, Saderi, Laura, Tiberi, Simon, Zumla, Alimuddin, Migliori, Giovanni Battista, and Sotgiu, Giovanni

Published
2022
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4. MDR/XDR-TB management of patients and contacts: Challenges facing the new decade. The 2020 clinical update by the Global Tuberculosis Network

Author

Arkub, T. Abu, Akkerman, O.W., Aleksa, A., Belilovski, E., Bernal, E., Blanc, F-X., Boeree, M., Borisov, S., Bruchfeld, J., Cadiñanos Loidi, J., Caminero, J.A., Carvalho, A.C., Cebrian Gallardo, J.J., Charalampos, Danila, E., Davies Forsman, L., Denholm, J., Dheda, K., Diel, R., Diktanas, S., Dobler, C., Enwerem, M., Esposito, S., Escobar Salinas, N., Filippov, A., Formenti, B., García García, J.M., Goletti, D., Gomez Rosso, R., Gualano, G., Isaakidis, P., Kaluzhenina, A., Koirala, S., Kuksa, L., Kunst, H., Li, Y., Magis-Escurra, C., Manfrin, V., Manga, S., Manika, K., Marchese, V., Martínez Robles, E., Maryandyshev, A., Matteelli, A., Mariani, A., Mazza-Stalder, J., Mello, F., Mendoza, L., Mesi, A., Miliauskas, S., Mustafa Hamdan, H., Ndjeka, N., Nieto Marcos, M., Ottenhoff, T.H.M., Palmero, D.J., Palmieri, F., Papavasileiou, A., Payen, M.C., Pontarelli, A., Pretti Dalcolmo, M., Quirós Fernandez, S., Romero, R., Rossato Silva, D., Santos, A.P., Seaworth, B., Sinitsyn, M., Skrahina, A., Solovic, I., Spanevello, A., Tadolini, M., Torres, C., Udwadia, Z., van den Boom, M., Volchenkov, G.V., Yedilbayev, A., Zaleskis, R., Zellweger, J.P., Migliori, Giovanni Battista, Tiberi, Simon, Zumla, Alimuddin, Petersen, Eskild, Chakaya, Jeremiah Muhwa, Wejse, Christian, Muñoz Torrico, Marcela, Duarte, Raquel, Alffenaar, Jan Willem, Schaaf, H. Simon, Marais, Ben J., Cirillo, Daniela Maria, Alagna, Riccardo, Rendon, Adrian, Pontali, Emanuele, Piubello, Alberto, Figueroa, José, Ferlazzo, Gabriella, García-Basteiro, Alberto, Centis, Rosella, Visca, Dina, D’Ambrosio, Lia, and Sotgiu, Giovanni

Published
2020
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12. Rapid Identification of Drug Resistance and Phylogeny in M. tuberculosis, Directly from Sputum Samples

Author

Barbosa-Amezcua, Martín, primary, Cuevas-Córdoba, Betzaida, additional, Fresno, Cristóbal, additional, Haase-Hernández, Joshua I., additional, Carrillo-Sánchez, Karol, additional, Mata-Rocha, Minerva, additional, Muñoz-Torrico, Marcela, additional, Bäcker, Claudia, additional, González-Covarrubias, Vanessa, additional, Alaez-Verson, Carmen, additional, and Soberón, Xavier, additional

Published
2022
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14. Screening for Tuberculosis in Migrants: A Survey by the Global Tuberculosis Network

Author

D’Ambrosio, Lia, primary, Centis, Rosella, additional, Dobler, Claudia C., additional, Tiberi, Simon, additional, Matteelli, Alberto, additional, Denholm, Justin, additional, Zenner, Dominik, additional, Al-Abri, Seif, additional, Alyaquobi, Fatma, additional, Arbex, Marcos Abdo, additional, Belilovskiy, Evgeny, additional, Blanc, François-Xavier, additional, Borisov, Sergey, additional, Carvalho, Anna Cristina C., additional, Chakaya, Jeremiah Muhwa, additional, Cocco, Nicola, additional, Codecasa, Luigi Ruffo, additional, Dalcolmo, Margareth Pretti, additional, Dheda, Keertan, additional, Dinh-Xuan, Anh Tuan, additional, Esposito, Susanna R., additional, García-García, José-María, additional, Li, Yang, additional, Manga, Selene, additional, Marchese, Valentina, additional, Muñoz Torrico, Marcela, additional, Pontali, Emanuele, additional, Rendon, Adrián, additional, Rossato Silva, Denise, additional, Singla, Rupak, additional, Solovic, Ivan, additional, Sotgiu, Giovanni, additional, van den Boom, Martin, additional, Nhung, Nguyen Viet, additional, Zellweger, Jean-Pierre, additional, and Migliori, Giovanni Battista, additional

Published
2021
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15. A bioinformatics pipeline for Mycobacterium tuberculosis sequencing that cleans contaminant reads from sputum samples

Author

Cuevas-Córdoba, Betzaida, primary, Fresno, Cristóbal, additional, Haase-Hernández, Joshua I., additional, Barbosa-Amezcua, Martín, additional, Mata-Rocha, Minerva, additional, Muñoz-Torrico, Marcela, additional, Salazar-Lezama, Miguel A., additional, Martínez-Orozco, José A., additional, Narváez-Díaz, Luis A., additional, Salas-Hernández, Jorge, additional, González-Covarrubias, Vanessa, additional, and Soberón, Xavier, additional

Published
2021
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19. Expression of Surfactant protein D (SP-D) distinguishes severe pandemic influenza A(H1N1) from COVID-19

Author

Choreño-Parra, José Alberto, Jiménez-Álvarez, Luis Armando, Ramírez-Martínez, Gustavo, Cruz-Lagunas, Alfredo, Thapa, Mahima, Fernández-López, Luis Alejandro, Carnalla-Cortés, Martha, Choreño-Parra, Eduardo M, Mena-Hernández, Lourdes, Sandoval-Vega, Montserrat, Hernández-Montiel, Erika Mariana, Hernández-García, Diana Lizzeth, Ramírez-Noyola, Jazmín Ariadna, Reyes-López, Cynthia Estefania, Domínguez-Faure, Andrea, Zamudio-López, Guillermo Yamil, Márquez-García, Eduardo, Moncada-Morales, Angélica, Mendoza-Milla, Criselda, Cervántes-Rosete, Diana, Muñoz-Torrico, Marcela, Luna-Rivero, Cesar, García-Latorre, Ethel A, Guadarrama-Ortíz, Parménides, Ávila-Moreno, Federico, Domínguez-Cherit, Guillermo, Rodríguez-Reyna, Tatiana Sofía, Mudd, Philip A, Hernández-Cárdenas, Carmen Margarita, Khader, Shabaana A, and Zúñiga, Joaquín

Subjects
Adult, Male, surfactant protein D, SARS-CoV-2, Coinfection, COVID-19, influenza A(H1N1)pdm09, Gene Expression, Enzyme-Linked Immunosorbent Assay, acute respiratory distress syndrome, Middle Aged, Prognosis, Pulmonary Surfactant-Associated Protein D, Severity of Illness Index, Young Adult, AcademicSubjects/MED00290, Influenza A Virus, H1N1 Subtype, Host-Pathogen Interactions, Influenza, Human, Major Article, Humans, Female, Symptom Assessment, Biomarkers, Aged
Abstract

The differentiation between influenza and coronavirus disease 2019 (COVID-19) could constitute a diagnostic challenge during the ongoing winter owing to their clinical similitude. Thus, novel biomarkers are required to enable making this distinction. Here, we evaluated whether the surfactant protein D (SP-D), a collectin produced at the alveolar epithelium with known immune properties, was useful to differentiate pandemic influenza A(H1N1) from COVID-19 in critically ill patients. Our results revealed high serum SP-D levels in patients with severe pandemic influenza but not those with COVID-19. This finding was validated in a separate cohort of mechanically ventilated patients with COVID-19 who also showed low plasma SP-D levels. However, plasma SP-D levels did not distinguish seasonal influenza from COVID-19 in mild-to-moderate disease. Finally, we found that high serum SP-D levels were associated with death and renal failure among severe pandemic influenza cases. Thus, our studies have identified SP-D as a unique biomarker expressed during severe pandemic influenza but not COVID-19.

Published
2021

20. Additional file 1 of Anti-tuberculosis chemotherapy alters TNFR2 expression on CD4+ lymphocytes in both drug-sensitive and -resistant tuberculosis: however, only drug-resistant tuberculosis maintains a pro-inflammatory profile after a long time

Author

Téllez-Navarrete, Norma A., Ramon-Luing, Lucero A., Muñoz-Torrico, Marcela, Preciado-García, Mario, Medina-Quero, Karen, Hernandez-Pando, Rogelio, and Chavez-Galan, Leslie

Subjects
immune system diseases, virus diseases, chemical and pharmacologic phenomena, hemic and immune systems
Abstract

Additional file 1: Table S1. Profiles of Drug-Resistant TB patients. Fig. S1. Representative flow cytometric analysis of PBMC in subjects with DS-TB and DR-TB. Peripheral mononuclear cells (PBMC) were analyzed by flow cytometry, representative analysis of one subject is showed. Cells gate was selected on the base of forward scatter (FSC)/side scatter (SSC). Then, singles FSC ad SSC dot plot were realized, posteriorly live cells gate was restricted (Pe-Texas Red negative), and CD3+CD4+ lymphocytes cells were identified. From the CD3+CD4+ gate, the co-expression of CD25+ and FOXP3 was measured to identify four subpopulations; activated CD4+ T cells (Q1: CD4+CD25+FOXP3-), conventional Treg cells (Q2: CD4+CD25+FOXP3+), unconventional Treg cells (Q3: CD4+CD25-FOXP3+), and others CD4+ T cells (Q4: CD4+CD25-FOXP3-) (A). Then, the expressions of tmTNF, tmTNFR1, and tmTNFR2 were measured in each CD4+ subpopulation (black histogram), FMO was used to identify the background signal (gray histogram) (B). Finally, from live cells gate, CD3+CD4+ cells were identified, and then the expressions CD45RA and CCR7 expression were evaluated: Naïve (CD45RA+/CCR7+), central memory (TCM, CD45RA-/CCR7+), effector memory (TEM, CD45RA-/CCR7-), and effector memory RA (TEMRA, CD45RA+/CCR7-) (C). Fig. S2. TEMRA and Naïve CD4+ T cells subpopulations are lower in DR-TB than in DS-TB after anti-TB therapy. Peripheral mononuclear cells (PBMC) from DS-TBand DR-TB patients were obtained at diagnosis time (basal), 2 months (2m) and 6 months (6m) of starting the anti-TB therapy, PBMC were prepared for flow cytometry. Then, frequency of CD4+ cell populations were measured: TEMRA cells (CD4+CD45RA+CCR7-) (A), Naïve cells (CD4+CD45RA+CCR7+) (B), EM cells (CD4+CD45RA-CCR7+)(C), and CM cells (CD4+CD45RA-CCR7-) (D). DS-TB=11, DR-TB=7. Bar graphs showing means ± SEM. One Way ANOVA with Dunn's post-test multiple comparisons tests.

Published
2021
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21. Expression of Surfactant Protein D Distinguishes Severe Pandemic Influenza A(H1N1) from Coronavirus Disease 2019

Author

Choreño-Parra, José Alberto, primary, Jiménez-Álvarez, Luis Armando, additional, Ramírez-Martínez, Gustavo, additional, Cruz-Lagunas, Alfredo, additional, Thapa, Mahima, additional, Fernández-López, Luis Alejandro, additional, Carnalla-Cortés, Martha, additional, Choreño-Parra, Eduardo M, additional, Mena-Hernández, Lourdes, additional, Sandoval-Vega, Montserrat, additional, Hernández-Montiel, Erika Mariana, additional, Hernández-García, Diana Lizzeth, additional, Ramírez-Noyola, Jazmín Ariadna, additional, Reyes-López, Cynthia Estefania, additional, Domínguez-Faure, Andrea, additional, Zamudio-López, Guillermo Yamil, additional, Márquez-García, Eduardo, additional, Moncada-Morales, Angélica, additional, Mendoza-Milla, Criselda, additional, Cervántes-Rosete, Diana, additional, Muñoz-Torrico, Marcela, additional, Luna-Rivero, Cesar, additional, García-Latorre, Ethel A, additional, Guadarrama-Ortíz, Parménides, additional, Ávila-Moreno, Federico, additional, Domínguez-Cherit, Guillermo, additional, Rodríguez-Reyna, Tatiana Sofía, additional, Mudd, Philip A, additional, Hernández-Cárdenas, Carmen Margarita, additional, Khader, Shabaana A, additional, and Zúñiga, Joaquín, additional

Published
2021
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22. Outcome of treatment of MDR-TB or drug-resistant patients treated with bedaquiline and delamanid: Results from a large global cohort

Author

Koirala, S., Borisov, Sergey, Danila, Edvardas, Mariandyshev, A., Shrestha, B., Lukhele, N., Dalcolmo, Margareth Pretti, Shakya, S.R., Miliauskas, S., Kuksa, Liga, Manga, Selene, Aleksa, Alena, Denholm, Justin, Khadka, H.B., Skrahina, Alena, Diktanas, S., Ferrarese, Maurizio, Bruchfeld, Judith, Koleva, A., Piubello, Alberto, Koirala, G.S., Udwadia, Zarir Farokh, Palmero, Domingo Juan, Muñoz Torrico, Marcela, GC, R., Gualano, Gina, Grecu, V.I., Motta, I., Papavasileiou, A., Li, Yang, Hoefsloot, Wouter, Kunst, Heinke, Mazza Stalder, J., Payen, Marie Christine, Akkerman, Onno, Bernal, Enrique, Manfrin, Vinicio, Matteelli, Alberto, Mustafa Hamdan, Hamdan, Nieto Marcos, Magnolia, Cadiñanos Loidi, Julen, Cebrian Gallardo, Jose Joaquín, Duarte, Raquel, Escobar Salinas, N., Gomez Rosso, Roscio Gomez, Laniado Laborín, Rafael, Martínez Robles, Elena, Quirós Fernandez, S., Rendón, Adrián, Solovic, Ivan, Tadolini, Marina, Viggiani, Pietro, Belilovski, Evgeny, Boeree, Martin J., Cai, Qingshan, Davidavičienė, Edita, Forsman, L.D., De Los Rios Jefe, Jorge, Drakšienė, J., Duga, A., Elamin, S.E., Filippov, Alexey, Garcia, A., Gaudiesiute, I., Gavazova, B., Gayoso, Regina, Gruslys, V., Jonsson, Jerker, Khimova, E., Madonsela, G., Magis Escurra, C., Marchese, Valentina, Matei, M., Moschos, C., Nakčerienė, B., Nicod, L., Palmieri, Fabrizio, Pontarelli, Agostina, Šmite, Agnese, Souleymane, Mahamadou Bassirou, Vescovo, Marisa, Zablockis, R., Zhurkin, Dmitry, Alffenaar, Jan Willem, Caminero, Jose A., Codecasa, Luigi Ruffo, García García, José María, Esposito, Susanna R., Saderi, L., Spanevello, Antonio, Visca, Dina, Tiberi, Simon, Pontali, Emanuele, Centis, Rosella, D'Ambrosio, L., van den Boom, Martin, Sotgiu, Giovanni, Migliori, Giovanni Battista, Koirala, S., Borisov, Sergey, Danila, Edvardas, Mariandyshev, A., Shrestha, B., Lukhele, N., Dalcolmo, Margareth Pretti, Shakya, S.R., Miliauskas, S., Kuksa, Liga, Manga, Selene, Aleksa, Alena, Denholm, Justin, Khadka, H.B., Skrahina, Alena, Diktanas, S., Ferrarese, Maurizio, Bruchfeld, Judith, Koleva, A., Piubello, Alberto, Koirala, G.S., Udwadia, Zarir Farokh, Palmero, Domingo Juan, Muñoz Torrico, Marcela, GC, R., Gualano, Gina, Grecu, V.I., Motta, I., Papavasileiou, A., Li, Yang, Hoefsloot, Wouter, Kunst, Heinke, Mazza Stalder, J., Payen, Marie Christine, Akkerman, Onno, Bernal, Enrique, Manfrin, Vinicio, Matteelli, Alberto, Mustafa Hamdan, Hamdan, Nieto Marcos, Magnolia, Cadiñanos Loidi, Julen, Cebrian Gallardo, Jose Joaquín, Duarte, Raquel, Escobar Salinas, N., Gomez Rosso, Roscio Gomez, Laniado Laborín, Rafael, Martínez Robles, Elena, Quirós Fernandez, S., Rendón, Adrián, Solovic, Ivan, Tadolini, Marina, Viggiani, Pietro, Belilovski, Evgeny, Boeree, Martin J., Cai, Qingshan, Davidavičienė, Edita, Forsman, L.D., De Los Rios Jefe, Jorge, Drakšienė, J., Duga, A., Elamin, S.E., Filippov, Alexey, Garcia, A., Gaudiesiute, I., Gavazova, B., Gayoso, Regina, Gruslys, V., Jonsson, Jerker, Khimova, E., Madonsela, G., Magis Escurra, C., Marchese, Valentina, Matei, M., Moschos, C., Nakčerienė, B., Nicod, L., Palmieri, Fabrizio, Pontarelli, Agostina, Šmite, Agnese, Souleymane, Mahamadou Bassirou, Vescovo, Marisa, Zablockis, R., Zhurkin, Dmitry, Alffenaar, Jan Willem, Caminero, Jose A., Codecasa, Luigi Ruffo, García García, José María, Esposito, Susanna R., Saderi, L., Spanevello, Antonio, Visca, Dina, Tiberi, Simon, Pontali, Emanuele, Centis, Rosella, D'Ambrosio, L., van den Boom, Martin, Sotgiu, Giovanni, and Migliori, Giovanni Battista

Published
2021

23. Screening for tuberculosis in migrants: a survey by the global tuberculosis network

Author

D’Ambrosio, Lia, Centis, Rosella, Dobler, Claudia C., Tiberi, Simon, Matteelli, Alberto, Denholm, Justin, Zenner, Dominik, Al-Abri, Seif, Alyaquobi, Fatma, Arbex, Marcos Abdo, Belilovski, Evgeny, Blanc, François Xavier, Borisov, Sergey, Carvalho, Anna Cristina C., Chakaya, Jeremiah Muhwa, Cocco, Nicola, Codecasa, Luigi Ruffo, Dalcolmo, Margareth Pretti, Dheda, Keertan, Dinh Xuan, Anh Tuan, Esposito, Susanna R., García García, José María, Li, Yang, Manga, Selene, Marchese, Valentina, Muñoz Torrico, Marcela, Pontali, Emanuele, Rendón, Adrián, Rossato Silva, Denise, Singla, Rupak, Solovic, Ivan, Sotgiu, Giovanni, Van den Boom, Martin, Nhung, Nguyen Viet, Zellweger, Jean Pierre, Migliori, Giovanni Battista, D’Ambrosio, Lia, Centis, Rosella, Dobler, Claudia C., Tiberi, Simon, Matteelli, Alberto, Denholm, Justin, Zenner, Dominik, Al-Abri, Seif, Alyaquobi, Fatma, Arbex, Marcos Abdo, Belilovski, Evgeny, Blanc, François Xavier, Borisov, Sergey, Carvalho, Anna Cristina C., Chakaya, Jeremiah Muhwa, Cocco, Nicola, Codecasa, Luigi Ruffo, Dalcolmo, Margareth Pretti, Dheda, Keertan, Dinh Xuan, Anh Tuan, Esposito, Susanna R., García García, José María, Li, Yang, Manga, Selene, Marchese, Valentina, Muñoz Torrico, Marcela, Pontali, Emanuele, Rendón, Adrián, Rossato Silva, Denise, Singla, Rupak, Solovic, Ivan, Sotgiu, Giovanni, Van den Boom, Martin, Nhung, Nguyen Viet, Zellweger, Jean Pierre, and Migliori, Giovanni Battista

Abstract

Tuberculosis (TB) does not respect borders, and migration confounds global TB control and elimination. Systematic screening of immigrants from TB high burden settings and—to a lesser degree TB infection (TBI)—is recommended in most countries with a low incidence of TB. The aim of the study was to evaluate the views of a diverse group of international health professionals on TB management among migrants. Participants expressed their level of agreement using a six-point Likert scale with different statements in an online survey available in English, French, Mandarin, Spanish, Portuguese and Russian. The survey consisted of eight sections, covering TB and TBI screening and treatment in migrants. A total of 1055 respondents from 80 countries and territories participated between November 2019 and April 2020. The largest professional groups were pulmonologists (16.8%), other clinicians (30.4%), and nurses (11.8%). Participants generally supported infection control and TB surveillance established practices (administrative interventions, personal protection, etc.), while they disagreed on how to diagnose and manage both TB and TBI, particularly on which TBI regimens to use and when patients should be hospitalised. The results of this first knowledge, attitude and practice study on TB screening and treatment in migrants will inform public health policy and educational resources.

Published
2021

24. Phenotype of Peripheral NK Cells in Latent, Active, and Meningeal Tuberculosis

Author

Choreño-Parra, José Alberto, primary, Jiménez-Álvarez, Luis Armando, additional, Maldonado-Díaz, Ellis Daniela, additional, Cárdenas, Graciela, additional, Fernández-Lopez, Luis Alejandro, additional, Soto-Hernandez, José Luis, additional, Muñoz-Torrico, Marcela, additional, Ramírez-Martínez, Gustavo, additional, Cruz-Lagunas, Alfredo, additional, Vega-López, Armando, additional, Domínguez-López, María Lilia, additional, Sánchez-Garibay, Carlos, additional, Guadarrama-Ortíz, Parménides, additional, Giono, Silvia, additional, Jiménez-Zamudio, Luis Antonio, additional, Khader, Shabaana A., additional, García-Latorre, Ethel A., additional, Salinas-Lara, Citlaltepetl, additional, and Zúñiga, Joaquín, additional

Published
2021
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26. Surveillance of adverse events in the treatment of drug-resistant tuberculosis: A global feasibility study

Author

Akkerman, Onno, Aleksa, Alena, Alffenaar, Jan-Willem, Al-Marzouqi, Nada Hassan, Arias-Guillén, Miguel, Belilovski, Evgeny, Bernal, Enrique, Boeree, Martin J., Borisov, Sergey E., Bruchfeld, Judith, Cadiñanos Loidi, Julen, Cai, Qingshan, Caminero, Jose A., Cebrian Gallardo, Jose Joaquín, Centis, Rosella, Codecasa, Luigi Ruffo, D’Ambrosio, Lia, Dalcolmo, Margareth, Danila, Edvardas, Dara, Masoud, Davidavičienė, Edita, Davies Forsman, Lina, De Los Rios Jefe, Jorge, Denholm, Justin, Duarte, Raquel, Elamin, Seifeldin Eltaeb, Ferrarese, Maurizio, Filippov, Alexey, Ganatra, Shashank, Garcia, Ana, García-García, José-María, Gayoso, Regina, Giraldo Montoya, Angela Maria, Gomez Rosso, Roscio Gomez, Gualano, Gina, Hoefsloot, Wouter, Ilievska-Poposka, Biljana, Jonsson, Jerker, Khimova, Elena, Kuksa, Liga, Kunst, Heinke, Laniado-Laborín, Rafael, Li, Yang, Magis-Escurra, Cecile, Manfrin, Vinicio, Manga, Selene, Marchese, Valentina, Martínez Robles, Elena, Maryandyshev, Andrei, Matteelli, Alberto, Migliori, Giovanni Battista, Mullerpattan, Jai B., Munoz-Torrico, Marcela, Mustafa Hamdan, Hamdan, Nieto Marcos, Magnolia, Noordin, Noorliza Mohamad, Palmero, Domingo Juan, Palmieri, Fabrizio, Payen, Marie-Christine, Piubello, Alberto, Pontali, Emanuele, Pontarelli, Agostina, Quirós, Sarai, Rendon, Adrian, Skrahina, Alena, Šmite, Agnese, Solovic, Ivan, Sotgiu, Giovanni, Souleymane, Mahamadou Bassirou, Spanevello, Antonio, Stošić, Maja, Tadolini, Marina, Tiberi, Simon, Udwadia, Zarir Farokh, van den Boom, Martin, Vescovo, Marisa, Viggiani, Pietro, Visca, Dina, Zhurkin, Dmitry, and Zignol, Matteo

Published
2019
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27. Worldwide Effects of Coronavirus Disease Pandemic on Tuberculosis Services, January–April 2020

Author

Migliori, Giovanni Battista, primary, Thong, Pei Min, additional, Akkerman, Onno, additional, Alffenaar, Jan-Willem, additional, Álvarez-Navascués, Fernando, additional, Assao-Neino, Mourtala Mohamed, additional, Bernard, Pascale Valérie, additional, Biala, Joshua Sorba, additional, Blanc, François-Xavier, additional, Bogorodskaya, Elena M., additional, Borisov, Sergey, additional, Buonsenso, Danilo, additional, Calnan, Marianne, additional, Castellotti, Paola Francesca, additional, Centis, Rosella, additional, Chakaya, Jeremiah Muhwa, additional, Cho, Jin-Gun, additional, Codecasa, Luigi Ruffo, additional, D'Ambrosio, Lia, additional, Denholm, Justin, additional, Enwerem, Martin, additional, Ferrarese, Maurizio, additional, Galvão, Tatiana, additional, García-Clemente, Marta, additional, García-García, José-María, additional, Gualano, Gina, additional, Gullón-Blanco, José Antonio, additional, Inwentarz, Sandra, additional, Ippolito, Giuseppe, additional, Kunst, Heinke, additional, Maryandyshev, Andrei, additional, Melazzini, Mario, additional, de Queiroz Mello, Fernanda Carvalho, additional, Muñoz-Torrico, Marcela, additional, Njungfiyini, Patrick Bung, additional, Palmero, Domingo Juan, additional, Palmieri, Fabrizio, additional, Piccioni, Pavilio, additional, Piubello, Alberto, additional, Rendon, Adrian, additional, Sabriá, Josefina, additional, Saporiti, Matteo, additional, Scognamiglio, Paola, additional, Sharma, Samridhi, additional, Silva, Denise Rossato, additional, Souleymane, Mahamadou Bassirou, additional, Spanevello, Antonio, additional, Tabernero, Eva, additional, Tadolini, Marina, additional, Tchangou, Michel Eke, additional, Thornton, Alice Boi Yatta, additional, Tiberi, Simon, additional, Udwadia, Zarir F., additional, Sotgiu, Giovanni, additional, Ong, Catherine Wei Min, additional, and Goletti, Delia, additional

Published
2020
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29. Prospective evaluation of improving fluoroquinolone exposure using centralised therapeutic drug monitoring (TDM) in patients with tuberculosis (PERFECT): a study protocol of a prospective multicentre cohort study

Author

van den Elsen, Simone HJ, primary, Sturkenboom, Marieke GG, additional, Akkerman, Onno, additional, Barkane, Linda, additional, Bruchfeld, Judith, additional, Eather, Geoffrey, additional, Heysell, Scott K, additional, Hurevich, Henadz, additional, Kuksa, Liga, additional, Kunst, Heinke, additional, Kuhlin, Johanna, additional, Manika, Katerina, additional, Moschos, Charalampos, additional, Mpagama, Stellah G, additional, Muñoz Torrico, Marcela, additional, Skrahina, Alena, additional, Sotgiu, Giovanni, additional, Tadolini, Marina, additional, Tiberi, Simon, additional, Volpato, Francesca, additional, van der Werf, Tjip S, additional, Wilson, Malcolm R, additional, Zúñiga, Joaquin, additional, Touw, Daan J, additional, Migliori, Giovanni B, additional, and Alffenaar, Jan-Willem, additional

Published
2020
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30. S100A8/A9 regulates CD11b expression and neutrophil recruitment during chronic tuberculosis

Author

Scott, Ninecia R., primary, Swanson, Rosemary V., additional, Al-Hammadi, Noor, additional, Domingo-Gonzalez, Racquel, additional, Rangel-Moreno, Javier, additional, Kriel, Belinda A., additional, Bucsan, Allison N., additional, Das, Shibali, additional, Ahmed, Mushtaq, additional, Mehra, Smriti, additional, Treerat, Puthayalai, additional, Cruz-Lagunas, Alfredo, additional, Jimenez-Alvarez, Luis, additional, Muñoz-Torrico, Marcela, additional, Bobadilla-Lozoya, Karen, additional, Vogl, Thomas, additional, Walzl, Gerhard, additional, du Plessis, Nelita, additional, Kaushal, Deepak, additional, Scriba, Thomas J., additional, Zúñiga, Joaquín, additional, and Khader, Shabaana A., additional

Published
2020
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31. Post-tuberculosis lung disease: a comparison of Brazilian, Italian, and Mexican cohorts.

Author

Rossato Silva, Denise, Ambos Freitas, Alana, Reis Guimarães, Amanda, D’Ambrosio, Lia, Centis, Rosella, Muñoz-Torrico, Marcela, Visca, Dina, and Battista Migliori, Giovanni

Subjects
PULMONARY function tests, TUBERCULOSIS, LUNG diseases, TUBERCULOSIS patients, BLOOD gases, MULTIDRUG-resistant tuberculosis
Abstract

Objective: To evaluate lung function in a cohort of patients with a history of pulmonary tuberculosis in Brazil, as well as to evaluate the decline in lung function over time and compare it with that observed in similar cohorts in Mexico and Italy. Methods: The three cohorts were compared in terms of age, smoking status, pulmonary function test results, six-minute walk test results, and arterial blood gas results. In the Brazilian cohort, pulmonary function test results, six-minute walk test results, and arterial blood gas results right after the end of tuberculosis treatment were compared with those obtained at the end of the follow-up period. Results: The three cohorts were very different regarding pulmonary function test results. The most common ventilatory patterns in the Brazilian, Italian, and Mexican cohorts were an obstructive pattern, a mixed pattern, and a normal pattern (in 58 patients [50.9%], in 18 patients [41.9%], and in 26 patients [44.1%], respectively). Only 2 multidrug-resistant tuberculosis cases were included in the Brazilian cohort, whereas, in the Mexican cohort, 27 cases were included (45.8%). Mean PaO2 and mean SaO2 were lower in the Mexican cohort than in the Brazilian cohort (p < 0.0001 and p < 0.002 for PaO2 and SaO2, respectively). In the Brazilian cohort, almost all functional parameters deteriorated over time. Conclusions: This study reinforces the importance of early and effective treatment of drug-susceptible tuberculosis patients, because multidrug-resistant tuberculosis increases lung damage. When patients complete their tuberculosis treatment, they should be evaluated as early as possible, and, if post-tuberculosis lung disease is diagnosed, they should be managed and offered pulmonary rehabilitation because there is evidence that it is effective in these patients. [ABSTRACT FROM AUTHOR]

Published
2022
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32. MDR/XDR-TB management of patients and contacts: Challenges facing the new decade. The 2020 clinical update by the Global Tuberculosis Network

Author

Migliori, Giovanni Battista, Tiberi, Simon, Zumla, Alimuddin, Petersen, Eskild, Chakaya, Jeremiah Muhwa, Wejse, Christian, Muñoz Torrico, Marcela, Duarte, Raquel, Alffenaar, Jan Willem, Schaaf, H. Simon, Marais, Ben J., Cirillo, Daniela Maria, Alagna, Riccardo, Rendón, Adrián, Pontali, Emanuele, Piubello, Alberto, Figueroa, José, Ferlazzo, Gabriella, García Basteiro, Alberto, Centis, Rosella, Visca, Dina, D’Ambrosio, Lia, Sotgiu, Giovanni, Migliori, Giovanni Battista, Tiberi, Simon, Zumla, Alimuddin, Petersen, Eskild, Chakaya, Jeremiah Muhwa, Wejse, Christian, Muñoz Torrico, Marcela, Duarte, Raquel, Alffenaar, Jan Willem, Schaaf, H. Simon, Marais, Ben J., Cirillo, Daniela Maria, Alagna, Riccardo, Rendón, Adrián, Pontali, Emanuele, Piubello, Alberto, Figueroa, José, Ferlazzo, Gabriella, García Basteiro, Alberto, Centis, Rosella, Visca, Dina, D’Ambrosio, Lia, and Sotgiu, Giovanni

Abstract

The continuous flow of new research articles on MDR-TB diagnosis, treatment, prevention and rehabilitation requires frequent update of existing guidelines. This review is aimed at providing clinicians and public health staff with an updated and easy-to-consult document arising from consensus of Global Tuberculosis Network (GTN) experts. The core published documents and guidelines have been reviewed, including the recently published MDR-TB WHO rapid advice and ATS/CDC/ERS/IDSA guidelines. After a rapid review of epidemiology and risk factors, the clinical priorities on MDR-TB diagnosis (including whole genome sequencing and drug-susceptibility testing interpretations) and treatment (treatment design and management, TB in children) are discussed. Furthermore, the review comprehensively describes the latest information on contact tracing and LTBI management in MDR- TB contacts, while providing guidance on post-treatment functional evaluation and rehabilitation of TB sequelae, infection control and other public health priorities

Published
2020

33. Surveillance of adverse events in the treatment of drug-resistant tuberculosis: first global report

Author

Borisov, Sergey, primary, Danila, Edvardas, additional, Maryandyshev, Andrei, additional, Dalcolmo, Margareth, additional, Miliauskas, Skaidrius, additional, Kuksa, Liga, additional, Manga, Selene, additional, Skrahina, Alena, additional, Diktanas, Saulius, additional, Codecasa, Luigi Ruffo, additional, Aleksa, Alena, additional, Bruchfeld, Judith, additional, Koleva, Antoniya, additional, Piubello, Alberto, additional, Udwadia, Zarir Farokh, additional, Akkerman, Onno W., additional, Belilovski, Evgeny, additional, Bernal, Enrique, additional, Boeree, Martin J., additional, Cadiñanos Loidi, Julen, additional, Cai, Qingshan, additional, Cebrian Gallardo, Jose Joaquín, additional, Dara, Masoud, additional, Davidavičienė, Edita, additional, Forsman, Lina Davies, additional, De Los Rios, Jorge, additional, Denholm, Justin, additional, Drakšienė, Jacinta, additional, Duarte, Raquel, additional, Elamin, Seifeldin Eltaeb, additional, Escobar Salinas, Nadia, additional, Ferrarese, Maurizio, additional, Filippov, Alexey, additional, Garcia, Ana, additional, García-García, José-María, additional, Gaudiesiute, Ieva, additional, Gavazova, Blagovesta, additional, Gayoso, Regina, additional, Gomez Rosso, Roscio, additional, Gruslys, Vygantas, additional, Gualano, Gina, additional, Hoefsloot, Wouter, additional, Jonsson, Jerker, additional, Khimova, Elena, additional, Kunst, Heinke, additional, Laniado-Laborín, Rafael, additional, Li, Yang, additional, Magis-Escurra, Cecile, additional, Manfrin, Vinicio, additional, Marchese, Valentina, additional, Martínez Robles, Elena, additional, Matteelli, Alberto, additional, Mazza-Stalder, Jesica, additional, Moschos, Charalampos, additional, Muñoz-Torrico, Marcela, additional, Mustafa Hamdan, Hamdan, additional, Nakčerienė, Birutė, additional, Nicod, Laurent, additional, Nieto Marcos, Magnolia, additional, Palmero, Domingo Juan, additional, Palmieri, Fabrizio, additional, Papavasileiou, Apostolos, additional, Payen, Marie-Christine, additional, Pontarelli, Agostina, additional, Quirós, Sarai, additional, Rendon, Adrian, additional, Saderi, Laura, additional, Šmite, Agnese, additional, Solovic, Ivan, additional, Souleymane, Mahamadou Bassirou, additional, Tadolini, Marina, additional, van den Boom, Martin, additional, Vescovo, Marisa, additional, Viggiani, Pietro, additional, Yedilbayev, Askar, additional, Zablockis, Rolandas, additional, Zhurkin, Dmitry, additional, Zignol, Matteo, additional, Visca, Dina, additional, Spanevello, Antonio, additional, Caminero, José A., additional, Alffenaar, Jan-Willem, additional, Tiberi, Simon, additional, Centis, Rosella, additional, D'Ambrosio, Lia, additional, Pontali, Emanuele, additional, Sotgiu, Giovanni, additional, and Migliori, Giovanni Battista, additional

Published
2019
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34. Fatores de risco para tuberculose: diabetes, tabagismo, álcool e uso de outras drogas

Author

Silva, Denise Rossato, Dalcolmo, Margareth Maria Pretti, Tiberi, Simon, Arbex, Marcos Abdo, Muñoz-Torrico, Marcela Verónica, Duarte, Raquel, D’Ambrosio, Lia, Visca, Dina, Rendon, Adrian, Gaga, Mina, Zumla, Allmuddin I., and Migliori, Giovanni Battista

Subjects
Tabagismo, Diabetes mellitus, Fatores de risco, Drogas ilícitas, Tuberculosis/therapy, Tuberculose, Extensively drugresistant tuberculosis, Revisão, Antitubercular agents, Tuberculosis, multidrug-resistant, Bebidas alcoólicas
Abstract

A tuberculose continua a ser um importante problema de saúde para a humanidade. Embora os esforços para controlar a epidemia tenham reduzido sua mortalidade e incidência, há vários fatores predisponentes a ser controlados a fim de reduzir a carga da doença. Este artigo de revisão aborda alguns dos fatores de risco associados à infecção por tuberculose, como diabetes, tabagismo, uso de álcool e uso de outras drogas, que podem também contribuir para maus resultados do tratamento da tuberculose. A tuberculose pode levar a complicações no curso e no manejo de outras doenças, como o diabetes. Portanto, é importante identificar essas comorbidades em pacientes com tuberculose a fim de assegurar um manejo adequado de ambas as condições. Tuberculosis continues to be a major public health problem. Although efforts to control the epidemic have reduced mortality and incidence, there are several predisposing factors that should be modified in order to reduce the burden of the disease. This review article will address some of the risk factors associated with tuberculosis infection and active tuberculosis, including diabetes, smoking, alcohol use, and the use of other drugs, all of which can also contribute to poor tuberculosis treatment results. Tuberculosis can also lead to complications in the course and management of other diseases, such as diabetes. It is therefore important to identify these comorbidities in tuberculosis patients in order to ensure adequate management of both conditions.

Published
2018

35. Risk factors for tuberculosis: diabetes, smoking, alcohol use, and the use of other drugs

Author

Silva, Denise Rossato, primary, Muñoz-Torrico, Marcela, additional, Duarte, Raquel, additional, Galvão, Tatiana, additional, Bonini, Eduardo Henrique, additional, Arbex, Flávio Ferlin, additional, Arbex, Marcos Abdo, additional, Augusto, Valéria Maria, additional, Rabahi, Marcelo Fouad, additional, and Mello, Fernanda Carvalho de Queiroz, additional

Published
2018
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36. Team approach to manage difficult-to-treat TB cases: Experiences in Europe and beyond

Author

D'Ambrosio, Lia, Bothamley, Graham Henry, Caminero Luna, José Antonio, Duarte, Raquel, Guglielmetti, Lorenzo, Muñoz Torrico, Marcela Verónica M., Payen, Marie-Christine, Saavedra Herrera, N., Salazar Lezama, Miguel Ángel M.A., Skrahina, Alena, Tadolini, Marina, Tiberi, Simon, Veziris, Nicolas, Migliori, Giovanni Battista, D'Ambrosio, Lia, Bothamley, Graham Henry, Caminero Luna, José Antonio, Duarte, Raquel, Guglielmetti, Lorenzo, Muñoz Torrico, Marcela Verónica M., Payen, Marie-Christine, Saavedra Herrera, N., Salazar Lezama, Miguel Ángel M.A., Skrahina, Alena, Tadolini, Marina, Tiberi, Simon, Veziris, Nicolas, and Migliori, Giovanni Battista

Abstract

As recommended by the World Health Organization (WHO), optimal management of MDR-TB cases can be ensured by a multi-speciality consultation body known as ‘TB Consilium’. This body usually includes different medical specialities, competences and perspectives (e.g. clinical expertise both for adults and children; surgical, radiological and public health expertise; psychological background and nursing experience, among others), thus lowering the risk of making mistakes – or managing the patients inappropriately, in order to improve their clinical outcomes. At present, several high MDR-TB burden countries in the different WHO regions (and beyond) have introduced TB Consilium-like bodies at the national or subnational level to reach consensus on the best treatment approach for their patients affected by TB. In addition, in countries/settings where a formal system of consultation does not exist, specialized staff from MDR-TB reference centres or international organizations usually spend a considerable amount of their working time responding to phone or e-mail clinical queries on how to manage M/XDR-TB cases. The aim of this manuscript is to describe the different experiences with the TB Consilia both at the international level (European Respiratory Society – ERS/WHO TB Consilium) and in some of the countries where this experience operates successfully in Europe and beyond. The Consilium experiences are described around the following topics: (1) history, aims and focus; (2) management and funding; (3) technical functioning and structure; (4) results achieved. In addition a comparative analysis of the TB Consilia in the different countries has been performed., SCOPUS: sh.j, info:eu-repo/semantics/published

Published
2018

37. Interleukin-17 limits hypoxia-inducible factor 1α and development of hypoxic granulomas during tuberculosis

Author

Domingo-Gonzalez, Racquel, primary, Das, Shibali, additional, Griffiths, Kristin L., additional, Ahmed, Mushtaq, additional, Bambouskova, Monika, additional, Gopal, Radha, additional, Gondi, Suhas, additional, Muñoz-Torrico, Marcela, additional, Salazar-Lezama, Miguel A., additional, Cruz-Lagunas, Alfredo, additional, Jiménez-Álvarez, Luis, additional, Ramirez-Martinez, Gustavo, additional, Espinosa-Soto, Ramón, additional, Sultana, Tamanna, additional, Lyons-Weiler, James, additional, Reinhart, Todd A., additional, Arcos, Jesus, additional, de la Luz Garcia-Hernandez, Maria, additional, Mastrangelo, Michael A., additional, Al-Hammadi, Noor, additional, Townsend, Reid, additional, Balada-Llasat, Joan-Miquel, additional, Torrelles, Jordi B., additional, Kaplan, Gilla, additional, Horne, William, additional, Kolls, Jay K., additional, Artyomov, Maxim N., additional, Rangel-Moreno, Javier, additional, Zúñiga, Joaquín, additional, and Khader, Shabaana A., additional

Published
2017
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38. Efecto del polimorfismo -197GA en la producción de IL-17A en respuesta a cepas hipervirulentas de M. tuberculosis

Author

Espinosa-Soto, Ramón, primary, Regino-Zamarripa, Nora Elemi, additional, León-Avila, Gloria, additional, Giono-Cerezo, Silvia, additional, Muñoz-Torrico, Marcela, additional, Salazar-Lezama, Miguel Ángel, additional, Márquez-García, Eduardo, additional, García-Sancho, María E, additional, Cruz-Lagunas, Alfredo, additional, Mendoza-Milla, Criselda, additional, Jiménez-Álvarez, Luis A, additional, Ramírez-Martínez, Gustavo, additional, and Zúñiga, Joaquín, additional

Published
2017
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39. Is there a rationale for pulmonary rehabilitation following successful chemotherapy for tuberculosis?

Author

Muñoz-Torrico, Marcela, primary, Rendon, Adrian, additional, Centis, Rosella, additional, D'Ambrosio, Lia, additional, Fuentes, Zhenia, additional, Torres-Duque, Carlos, additional, Mello, Fernanda, additional, Dalcolmo, Margareth, additional, Pérez-Padilla, Rogelio, additional, Spanevello, Antonio, additional, and Migliori, Giovanni Battista, additional

Published
2016
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40. Fatores de risco para tuberculose: diabetes, tabagismo, álcool e uso de outras drogas.

Author

Rossato Silva, Denise, Muñoz-Torrico, Marcela, Duarte, Raquel, Galvão, Tatiana, Henrique Bonini, Eduardo, Ferlin Arbex, Flávio, Abdo Arbex, Marcos, Maria Augusto, Valéria, Fouad Rabahi, Marcelo, and de Queiroz Mello, Fernanda Carvalho

Abstract

Copyright of Brazilian Journal of Pulmonology / Jornal Brasileiro de Pneumologia is the property of Sociedade Brasileira de Pneumologia e Tisiologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2018
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42. Clinical cases

Author

Tiberi, Simon, primary, Payen, Marie Christine, additional, Manika, Katerina, additional, Ladeira, Inês, additional, Gonzalez Sanz, Marta, additional, and Muñoz-Torrico, Marcela, additional

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43. Humoral and cellular responses to a non-adjuvanted monovalent H1N1 pandemic influenza vaccine in hospital employees

Author

Herrera, Ma Teresa, primary, Gonzalez, Yolanda, additional, Juárez, Esmeralda, additional, Hernández-Sánchez, Fernando, additional, Carranza, Claudia, additional, Sarabia, Carmen, additional, Guzman-Beltran, Silvia, additional, Manjarrez, Ma Eugenia, additional, Muñoz-Torrico, Marcela, additional, Garcia-Garcia, Lourdes, additional, Sada, Eduardo, additional, and Torres, Martha, additional

Published
2013
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45. Post-tuberculosis lung disease: a comparison of Brazilian, Italian, and Mexican cohorts.

Author

Silva DR, Freitas AA, Guimarães AR, D'Ambrosio L, Centis R, Muñoz-Torrico M, Visca D, and Migliori GB

Subjects
Brazil epidemiology, Humans, Lung, Mexico epidemiology, Oxygen, Tuberculosis, Tuberculosis, Multidrug-Resistant drug therapy, Tuberculosis, Multidrug-Resistant epidemiology, Tuberculosis, Pulmonary drug therapy, Tuberculosis, Pulmonary epidemiology
Abstract

Objective: To evaluate lung function in a cohort of patients with a history of pulmonary tuberculosis in Brazil, as well as to evaluate the decline in lung function over time and compare it with that observed in similar cohorts in Mexico and Italy., Methods: The three cohorts were compared in terms of age, smoking status, pulmonary function test results, six-minute walk test results, and arterial blood gas results. In the Brazilian cohort, pulmonary function test results, six-minute walk test results, and arterial blood gas results right after the end of tuberculosis treatment were compared with those obtained at the end of the follow-up period., Results: The three cohorts were very different regarding pulmonary function test results. The most common ventilatory patterns in the Brazilian, Italian, and Mexican cohorts were an obstructive pattern, a mixed pattern, and a normal pattern (in 58 patients [50.9%], in 18 patients [41.9%], and in 26 patients [44.1%], respectively). Only 2 multidrug-resistant tuberculosis cases were included in the Brazilian cohort, whereas, in the Mexican cohort, 27 cases were included (45.8%). Mean PaO2 and mean SaO2 were lower in the Mexican cohort than in the Brazilian cohort (p < 0.0001 and p < 0.002 for PaO2 and SaO2, respectively). In the Brazilian cohort, almost all functional parameters deteriorated over time., Conclusions: This study reinforces the importance of early and effective treatment of drug-susceptible tuberculosis patients, because multidrug-resistant tuberculosis increases lung damage. When patients complete their tuberculosis treatment, they should be evaluated as early as possible, and, if post-tuberculosis lung disease is diagnosed, they should be managed and offered pulmonary rehabilitation because there is evidence that it is effective in these patients.

Published
2022
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46. Screening for Tuberculosis in Migrants: A Survey by the Global Tuberculosis Network.

Author

D'Ambrosio L, Centis R, Dobler CC, Tiberi S, Matteelli A, Denholm J, Zenner D, Al-Abri S, Alyaquobi F, Arbex MA, Belilovskiy E, Blanc FX, Borisov S, Carvalho ACC, Chakaya JM, Cocco N, Codecasa LR, Dalcolmo MP, Dheda K, Dinh-Xuan AT, Esposito SR, García-García JM, Li Y, Manga S, Marchese V, Muñoz Torrico M, Pontali E, Rendon A, Rossato Silva D, Singla R, Solovic I, Sotgiu G, van den Boom M, Nhung NV, Zellweger JP, and Migliori GB

Abstract

Tuberculosis (TB) does not respect borders, and migration confounds global TB control and elimination. Systematic screening of immigrants from TB high burden settings and-to a lesser degree TB infection (TBI)-is recommended in most countries with a low incidence of TB. The aim of the study was to evaluate the views of a diverse group of international health professionals on TB management among migrants. Participants expressed their level of agreement using a six-point Likert scale with different statements in an online survey available in English, French, Mandarin, Spanish, Portuguese and Russian. The survey consisted of eight sections, covering TB and TBI screening and treatment in migrants. A total of 1055 respondents from 80 countries and territories participated between November 2019 and April 2020. The largest professional groups were pulmonologists (16.8%), other clinicians (30.4%), and nurses (11.8%). Participants generally supported infection control and TB surveillance established practices (administrative interventions, personal protection, etc.), while they disagreed on how to diagnose and manage both TB and TBI, particularly on which TBI regimens to use and when patients should be hospitalised. The results of this first knowledge, attitude and practice study on TB screening and treatment in migrants will inform public health policy and educational resources.

Published
2021
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47. [The response of the intensive care units during the influenza A H1N1 pandemic: the experience in Chiapas, Mexico].

Author

Volkow P, Bautista E, de la Rosa M, Manzano G, Muñoz-Torrico MV, and Pérez-Padilla R

Subjects
Critical Care, Humans, Mexico epidemiology, Ventilators, Mechanical, Influenza A Virus, H1N1 Subtype, Influenza, Human epidemiology, Influenza, Human therapy, Intensive Care Units statistics & numerical data, Pandemics
Abstract

Respiratory virus epidemics had highlighted the importance of the Intensive Care Unit (ICU) to save life of severe cases. ICU functioning and outcomes depends on infrastructure and trained healthcare personnel. In Chiapas, a Southern state in Mexico,an area to care for severe H1N1 cases on respiratory distress during the second H1N1-2009 outbreak, had to be habilitated.This had to be done without sufficient equipment and ICU un-experienced healthcare workers. It was possible to improve its performance through training and standardizing attention care processes for critically ill patients. In preparation for the next pandemic it is essential to designate hospitals with preexistent ICU where to refer severe cases and avoid improvisations.The experience in Chiapas showed that standardization of medical care processes are clue and in case of an overwhelming emergency it is possible to habilitate an ICU although it is imperative to take advantage from installed facilities in each city with the official authority.

Published
2011
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