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11 results on '"Muralidharan, Geethika"'

1. Multi-meridian corneal imaging of air-puff induced deformation for improved detection of biomechanical abnormalities

Author

Curatolo, Andrea, primary, Birkenfeld, Judith S., additional, Martinez-Enriquez, Eduardo, additional, Germann, James A., additional, Muralidharan, Geethika, additional, Palací, Jesús, additional, Pascual, Daniel, additional, Eliasy, Ashkan, additional, Abass, Ahmed, additional, Solarski, Jędrzej, additional, Karnowski, Karol, additional, Wojtkowski, Maciej, additional, Elsheikh, Ahmed, additional, and Marcos, Susana, additional

Published
2020
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2. Effect of fixational eye movements in corneal topography measurement with OCT

Author

Castro, Alberto de, Martínez-Enríquez, Eduardo, Muralidharan, Geethika, Curatolo, A., Marcos, Susana, European Commission, and Ministerio de Economía y Competitividad (España)

Abstract

1 pag. -- This is a 2020 ARVO Annual Meeting abstract., Support COFUND Multiply: European Research Council (ERC) under European Union’s Horizon 2020 research and innovation programme H2020-MSCA-COFUND-2015-FP-713694; Spanish government grant FIS2017-84753-R

Published
2020

3. Customized swept-source optical coherence tomography system for air-puff induced corneal deformation imaging on multiple meridians

Author

Curatolo, A., Birkenfeld, J., Martínez-Enríquez, Eduardo, Germann, James, Palací, J., Pascual, Daniel, Muralidharan, Geethika, Solarski, J., Karnowski, Karol, Wojtkowski, Maciej, and Marcos, Susana

Abstract

PIE BiOS, San Francisco, California, United States, 17 Marzo 2020. -- SPIE Proceedings Vol. 11218: Ophthalmic Technologies XXX . -- https://www.spiedigitallibrary.org/conference-proceedings-of-spie/11218/2546050/Customized-swept-source-optical-coherence-tomography-system-for-air-puff/10.1117/12.2546050.full?SSO=1

Published
2020

4. Crystalline lens accommodation through multifocal corrections

Author

Muralidharan, Geethika, Birkenfeld, J., Viñas, María, Curatolo, A., Martínez-Enríquez, Eduardo, Castro, Alberto de, and Marcos, Susana

Abstract

Vancouver Convention Centre, Vancouver, B.C., April 28 – May 2 (2019)

Published
2019

5. Customized swept-source optical coherence tomography system for air-puff induced corneal deformation imaging on multiple meridians

Author

Curatolo, Andrea, Birkenfeld, J., Martínez-Enríquez, Eduardo, Germann, James, Palací, J., Pascual, Daniel, Muralidharan, Geethika, Solarski, J., Karnowski, Karol, Wojtkowski, Maciej, Marcos, Susana, Curatolo, Andrea, Birkenfeld, J., Martínez-Enríquez, Eduardo, Germann, James, Palací, J., Pascual, Daniel, Muralidharan, Geethika, Solarski, J., Karnowski, Karol, Wojtkowski, Maciej, and Marcos, Susana

Published
2020

6. Effect of fixational eye movements in corneal topography measurement with OCT

Author

European Commission, Ministerio de Economía y Competitividad (España), Castro, Alberto de, Martínez-Enríquez, Eduardo, Muralidharan, Geethika, Curatolo, Andrea, Marcos, Susana, European Commission, Ministerio de Economía y Competitividad (España), Castro, Alberto de, Martínez-Enríquez, Eduardo, Muralidharan, Geethika, Curatolo, Andrea, and Marcos, Susana

Published
2020

7. Detecting deformation asymmetries on multiple meridians in an ex vivo keratoconic eye model

Author

European Commission, Ministerio de Economía y Competitividad (España), Curatolo, Andrea, Birkenfeld, J., Martínez-Enríquez, Eduardo, Germann, James, Palací, J., Pascual, Daniel, Muralidharan, Geethika, Eliasy, A., Abass, A., Solarski, J., Karnowski, Karol, Wojtkowski, Maciej, Elsheikh, A., Marcos, Susana, European Commission, Ministerio de Economía y Competitividad (España), Curatolo, Andrea, Birkenfeld, J., Martínez-Enríquez, Eduardo, Germann, James, Palací, J., Pascual, Daniel, Muralidharan, Geethika, Eliasy, A., Abass, A., Solarski, J., Karnowski, Karol, Wojtkowski, Maciej, Elsheikh, A., and Marcos, Susana

Published
2020

8. Multi-meridian corneal imaging of air-puff induced deformation for improved detection of biomechanical abnormalities

Author

European Commission, Ministerio de Ciencia, Innovación y Universidades (España), Foundation for Polish Science, Curatolo, Andrea, Birkenfeld, J., Martínez-Enríquez, Eduardo, Germann, James, Muralidharan, Geethika, Palací, J., Pascual, Daniel, Eliasy, A., Abass, A., Solarski, J., Karnowski, K., Wojtkowski, M., Elsheikh, A., Marcos, Susana, European Commission, Ministerio de Ciencia, Innovación y Universidades (España), Foundation for Polish Science, Curatolo, Andrea, Birkenfeld, J., Martínez-Enríquez, Eduardo, Germann, James, Muralidharan, Geethika, Palací, J., Pascual, Daniel, Eliasy, A., Abass, A., Solarski, J., Karnowski, K., Wojtkowski, M., Elsheikh, A., and Marcos, Susana

Abstract

Corneal biomechanics play a fundamental role in the genesis and progression of corneal pathologies, such as keratoconus; in corneal remodeling after corneal surgery; and in affecting the measurement accuracy of glaucoma biomarkers, such as the intraocular pressure (IOP). Air-puff induced corneal deformation imaging reveals information highlighting normal and pathological corneal response to a non-contact mechanical excitation. However, current commercial systems are limited to monitoring corneal deformation only on one corneal meridian. Here, we present a novel custom-developed swept-source optical coherence tomography (SSOCT) system, coupled with a collinear air-puff excitation, capable of acquiring dynamic corneal deformation on multiple meridians. Backed by numerical simulations of corneal deformations, we propose two different scan patterns, aided by low coil impedance galvanometric scan mirrors that permit an appropriate compromise between temporal and spatial sampling of the corneal deformation profiles. We customized the air-puff module to provide an unobstructed SSOCT field of view and different peak pressures, air-puff durations, and distances to the eye. We acquired multi-meridian corneal deformation profiles (a) in healthy human eyes in vivo, (b) in porcine eyes ex vivo under varying controlled IOP, and (c) in a keratoconus-mimicking porcine eye ex vivo. We detected deformation asymmetries, as predicted by numerical simulations, otherwise missed on a single meridian that will substantially aid in corneal biomechanics diagnostics and pathology screening.

Published
2020

9. Customized swept-source optical coherence tomography system for air-puff induced corneal deformation imaging on multiple meridians (Conference Presentation)

Author

Curatolo, Andrea, primary, Birkenfeld, Judith, additional, Martínez, Eduardo, additional, Germann, James A., additional, Palací, Jesús, additional, Pascual, Daniel, additional, Muralidharan, Geethika, additional, Solarski, Jedrzej, additional, Karnowski, Karol, additional, Wojtkowski, Maciej, additional, and Marcos, Susana, additional

Published
2020
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11. Morphological changes of human crystalline lens in myopia

Author

European Commission, Ministerio de Ciencia, Innovación y Universidades (España), Muralidharan, Geethika, Martínez-Enríquez, Eduardo, Birkenfeld, J., Velasco Ocaña, Miriam, Pérez Merino, Pablo, Marcos, Susana, European Commission, Ministerio de Ciencia, Innovación y Universidades (España), Muralidharan, Geethika, Martínez-Enríquez, Eduardo, Birkenfeld, J., Velasco Ocaña, Miriam, Pérez Merino, Pablo, and Marcos, Susana

Abstract

Ocular biometric parameters, including full shape crystalline lens, were assessed in myopes and emmetropes using 3-D optical coherence tomography. The anterior chamber depth, the radius of the curvature of the anterior cornea, anterior lens, and posterior lens, lens thickness, lens equatorial diameter, surface area, equatorial position, volume, and power, were evaluated as functions of refractive errors and axial lengths while controlling for age effects. The crystalline lens appears to change with myopia consistent with lens thinning, equatorial, and capsular stretching while keeping constant volume. Axial elongation appears counteracted by a crystalline lens power reduction, while corneal power remains unaffected.

Published
2019

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