12,822 results on '"Muresan AN"'
Search Results
2. Diversities and similarities exhibited by multi-planetary systems and their architectures: I. Orbital spacings
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Muresan, Alexandra, Persson, Carina, and Fridlund, Malcolm
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Astrophysics - Earth and Planetary Astrophysics - Abstract
The rich diversity of multi-planetary systems and their architectures is greatly contrasted by the uniformity exhibited within many of these systems. Previous studies have shown that compact Kepler systems tend to exhibit a peas-in-a-pod architecture: Planets in the same system tend to have similar sizes and masses and be regularly spaced in orbits with low eccentricities and mutual inclinations. This work extends on previous research and examines a larger and more diverse sample comprising all the systems with a minimum of three confirmed planets, resulting in 282 systems and 991 planets. We investigated the system architectures, focusing on the orbital spacings between adjacent planets as well as their relationships with the planets' sizes and masses. We also quantified the similarities of the sizes, masses, and spacings of planets within each system, conducting both intra- and inter-system analyses. Our results corroborate previous research showing that planets orbiting the same star tend to be regularly spaced and that pairs of adjacent planets with radii<1 R_Earth predominantly have orbital period ratios (PRs)<2. In contrast to other studies, we identified a significant similarity of adjacent orbital spacings not only at PRs<4 but also at 1.17
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- 2024
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3. Metabolomic biomarkers of polycystic ovary syndrome related-obesity: a review of the literature
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Vonica Camelia Larisa, Farcas Anca Daniela, Roman Gabriela, Muresan Andrada Alina, Fodor Adriana, Cernea Simona, and Georgescu Carmen Emanuela
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untargeted metabolomics ,polycystic ovary syndrome ,obesity ,biomarkers ,targeted metabolomics ,Medicine - Abstract
Background and objectives: Polycystic ovary syndrome (PCOS) displays a phenotype-dependent cardio-metabolic risk. By performing a systematic search of the literature, we aimed to summarize metabolomic signatures associated with obesity in PCOS women.
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- 2020
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4. Latent Space Interpretation for Stylistic Analysis and Explainable Authorship Attribution
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Alshomary, Milad, Ri, Narutatsu, Apidianaki, Marianna, Patel, Ajay, Muresan, Smaranda, and McKeown, Kathleen
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Computer Science - Computation and Language - Abstract
Recent state-of-the-art authorship attribution methods learn authorship representations of texts in a latent, non-interpretable space, hindering their usability in real-world applications. Our work proposes a novel approach to interpreting these learned embeddings by identifying representative points in the latent space and utilizing LLMs to generate informative natural language descriptions of the writing style of each point. We evaluate the alignment of our interpretable space with the latent one and find that it achieves the best prediction agreement compared to other baselines. Additionally, we conduct a human evaluation to assess the quality of these style descriptions, validating their utility as explanations for the latent space. Finally, we investigate whether human performance on the challenging AA task improves when aided by our system's explanations, finding an average improvement of around +20% in accuracy., Comment: 8 pages, 8 figures, under review
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- 2024
5. Enhanced Fractional-Order Nonsingular Terminal Sliding Mode Control for Fully Submerged Hydrofoil Craft with Actuator Saturation
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Niu, Hongmin, Zhao, Shiquan, Muresan, Cristina I., and Ionescu, Clara Mihaela
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- 2025
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6. Latent Space Interpretation for Stylistic Analysis and Explainable Authorship Attribution.
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Milad Alshomary, Narutatsu Ri, Marianna Apidianaki, Ajay Patel, Smaranda Muresan, and Kathleen R. McKeown
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- 2025
7. Autotuners and Fractional Calculus. Applications to the Control of Nonlinear Processes
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Muresan, Cristina, Birs, Isabela, De Keyser, Robin, Yabuno, Hiroshi, editor, Lacarbonara, Walter, editor, Balachandran, Balakumar, editor, Fidlin, Alexander, editor, Rega, Giuseppe, editor, Kuroda, Masaharu, editor, and Maruyama, Shinichi, editor
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- 2025
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8. 'Is ChatGPT a Better Explainer than My Professor?': Evaluating the Explanation Capabilities of LLMs in Conversation Compared to a Human Baseline
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Li, Grace, Alshomary, Milad, and Muresan, Smaranda
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Computer Science - Computation and Language - Abstract
Explanations form the foundation of knowledge sharing and build upon communication principles, social dynamics, and learning theories. We focus specifically on conversational approaches for explanations because the context is highly adaptive and interactive. Our research leverages previous work on explanatory acts, a framework for understanding the different strategies that explainers and explainees employ in a conversation to both explain, understand, and engage with the other party. We use the 5-Levels dataset was constructed from the WIRED YouTube series by Wachsmuth et al., and later annotated by Booshehri et al. with explanatory acts. These annotations provide a framework for understanding how explainers and explainees structure their response when crafting a response. With the rise of generative AI in the past year, we hope to better understand the capabilities of Large Language Models (LLMs) and how they can augment expert explainer's capabilities in conversational settings. To achieve this goal, the 5-Levels dataset (We use Booshehri et al.'s 2023 annotated dataset with explanatory acts.) allows us to audit the ability of LLMs in engaging in explanation dialogues. To evaluate the effectiveness of LLMs in generating explainer responses, we compared 3 different strategies, we asked human annotators to evaluate 3 different strategies: human explainer response, GPT4 standard response, GPT4 response with Explanation Moves., Comment: 6 figures, 5 pages
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- 2024
9. Connecting the Dots: Evaluating Abstract Reasoning Capabilities of LLMs Using the New York Times Connections Word Game
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Samadarshi, Prisha, Mustafa, Mariam, Kulkarni, Anushka, Rothkopf, Raven, Chakrabarty, Tuhin, and Muresan, Smaranda
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Computer Science - Computation and Language ,Computer Science - Artificial Intelligence - Abstract
The New York Times Connections game has emerged as a popular and challenging pursuit for word puzzle enthusiasts. We collect 438 Connections games to evaluate the performance of state-of-the-art large language models (LLMs) against expert and novice human players. Our results show that even the best performing LLM, Claude 3.5 Sonnet, which has otherwise shown impressive reasoning abilities on a wide variety of benchmarks, can only fully solve 18% of the games. Novice and expert players perform better than Claude 3.5 Sonnet, with expert human players significantly outperforming it. We create a taxonomy of the knowledge types required to successfully cluster and categorize words in the Connections game. We find that while LLMs perform relatively well on categorizing words based on semantic relations they struggle with other types of knowledge such as Encyclopedic Knowledge, Multiword Expressions or knowledge that combines both Word Form and Meaning. Our results establish the New York Times Connections game as a challenging benchmark for evaluating abstract reasoning capabilities in AI systems.
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- 2024
10. Understanding Figurative Meaning through Explainable Visual Entailment
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Saakyan, Arkadiy, Kulkarni, Shreyas, Chakrabarty, Tuhin, and Muresan, Smaranda
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Computer Science - Computation and Language ,Computer Science - Artificial Intelligence ,Computer Science - Computer Vision and Pattern Recognition - Abstract
Large Vision-Language Models (VLMs) have demonstrated strong capabilities in tasks requiring a fine-grained understanding of literal meaning in images and text, such as visual question-answering or visual entailment. However, there has been little exploration of the capabilities of these models when presented with images and captions containing figurative meaning, such as metaphors or humor. To close this gap, we propose a new task framing the figurative meaning understanding problem as an explainable visual entailment task, where the model has to predict whether the image (premise) entails a caption (hypothesis) and justify the predicted label with a textual explanation. The figurative phenomena can be present in the image, in the caption, or both. Using a human-AI collaboration approach, we build the accompanying expert-verified dataset V-FLUTE, containing 6,027 {image, caption, label, explanation} instances spanning five diverse figurative phenomena: metaphors, similes, idioms, sarcasm, and humor. Through automatic evaluation, we find that VLMs struggle to generalize from literal to figurative meaning, particularly when it is present in images. Further, we identify common types of errors in VLM reasoning (hallucination and incomplete or unsound reasoning) across classes of models via human evaluation., Comment: NAACL 2025 Main Conference
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- 2024
11. Navigating the Landscape of Hint Generation Research: From the Past to the Future
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Jangra, Anubhav, Mozafari, Jamshid, Jatowt, Adam, and Muresan, Smaranda
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Computer Science - Computation and Language ,Computer Science - Human-Computer Interaction - Abstract
Digital education has gained popularity in the last decade, especially after the COVID-19 pandemic. With the improving capabilities of large language models to reason and communicate with users, envisioning intelligent tutoring systems (ITSs) that can facilitate self-learning is not very far-fetched. One integral component to fulfill this vision is the ability to give accurate and effective feedback via hints to scaffold the learning process. In this survey article, we present a comprehensive review of prior research on hint generation, aiming to bridge the gap between research in education and cognitive science, and research in AI and Natural Language Processing. Informed by our findings, we propose a formal definition of the hint generation task, and discuss the roadmap of building an effective hint generation system aligned with the formal definition, including open challenges, future directions and ethical considerations., Comment: Submitted to TACL'24
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- 2024
12. Studies on morpho-structure and ionic conductivity of apatite-type lanthanum silicate doped with transitional metal cations
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Perhaita, Ioana, Muresan, Laura Elena, Borodi, Gheorghe, Popa, Adriana, Nicoara, Adrian, and Tudoran, Lucian Barbu
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- 2024
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13. Magnetic resonance used as a differential diagnostic tool between inflammatory cancer of the sigmoid and acute sigmoid diverticulitis
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Cornel Dragos Cheregi, Teodora Gabriela Alexescu, Andrei Vasile Pascalau, Ovidiu Laurean Pop, Calin Magheru, Ioana Maria Muresan, Nicoleta Ramona Suciu, Maur Sebastian Horgos, and Mihai Stefan Muresan
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diverticulitis of the sigmoid ,sigmoid cancer ,differential diagnostic tool ,mri ,Medicine (General) ,R5-920 - Abstract
Sigmoid diverticulitis is a common disease characterized by a well-standardized diagnostic approach and treatment. Colorectal cancer is the third most common malignancy worldwide, irrespective of gender. In 2020, CRC global-related mortality rate was estimated at 935 173 cases, with an incidence of 9.3% in men and 9.5% in women. The diagnosis of acute diverticulitis is always made by performing a contrast-enhanced-computed tomography (CT) of the abdomen. Current diagnosis guidelines do not recommend the use of a magnetic resonance imaging (MRI) for further and more precise assessment of a suspected sigmoid diverticulitis diagnosed by CT. Early lower-gastrointestinal (lower-GI) endoscopy is rarely conducted; thus, the diagnosis delay could have a negative impact over the oncological outcome of the disease. Few and scarce data can be found related to this issue, with only a recent Swedish study paying attention towards early identification of neoplastic disease residing on a background of sigmoid diverticulitis, facilitated by MRI. The purpose of this study is to evaluate the feasibility of systematically performing an abdominal MRI included in the primary assessment of acute diverticulitis already diagnosed by CT, in order to argument in favor of an early lower-GI endoscopy where a positive MRI for neoplasia is found.
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- 2024
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14. Large Language Models are Few-Shot Training Example Generators: A Case Study in Fallacy Recognition
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Alhindi, Tariq, Muresan, Smaranda, and Nakov, Preslav
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Computer Science - Computation and Language - Abstract
Recognizing fallacies is crucial for ensuring the quality and validity of arguments across various domains. However, computational fallacy recognition faces challenges due to the diverse genres, domains, and types of fallacies found in datasets. This leads to a highly multi-class, and even multi-label, setup with substantial class imbalance. In this study, we aim to enhance existing models for fallacy recognition by incorporating additional context and by leveraging large language models to generate synthetic data, thus increasing the representation of the infrequent classes. We experiment with GPT3.5 to generate synthetic examples and we examine the impact of prompt settings for this. Moreover, we explore zero-shot and few-shot scenarios to evaluate the effectiveness of using the generated examples for training smaller models within a unified fallacy recognition framework. Furthermore, we analyze the overlap between the synthetic data and existing fallacy datasets. Finally, we investigate the usefulness of providing supplementary context for detecting fallacy types that need such context, e.g., diversion fallacies. Our evaluation results demonstrate consistent improvements across fallacy types, datasets, and generators. The code and the synthetic datasets are all publicly available.
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- 2023
15. Identifying Self-Disclosures of Use, Misuse and Addiction in Community-based Social Media Posts
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Yang, Chenghao, Chakrabarty, Tuhin, Hochstatter, Karli R, Slavin, Melissa N, El-Bassel, Nabila, and Muresan, Smaranda
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Computer Science - Computation and Language - Abstract
In the last decade, the United States has lost more than 500,000 people from an overdose involving prescription and illicit opioids making it a national public health emergency (USDHHS, 2017). Medical practitioners require robust and timely tools that can effectively identify at-risk patients. Community-based social media platforms such as Reddit allow self-disclosure for users to discuss otherwise sensitive drug-related behaviors. We present a moderate size corpus of 2500 opioid-related posts from various subreddits labeled with six different phases of opioid use: Medical Use, Misuse, Addiction, Recovery, Relapse, Not Using. For every post, we annotate span-level extractive explanations and crucially study their role both in annotation quality and model development. We evaluate several state-of-the-art models in a supervised, few-shot, or zero-shot setting. Experimental results and error analysis show that identifying the phases of opioid use disorder is highly contextual and challenging. However, we find that using explanations during modeling leads to a significant boost in classification accuracy demonstrating their beneficial role in a high-stakes domain such as studying the opioid use disorder continuum., Comment: NAACL 2024 Findings (Camera-Ready Version). Codes and Data are available at https://github.com/yangalan123/OpioidID
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- 2023
16. Learning to Follow Object-Centric Image Editing Instructions Faithfully
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Chakrabarty, Tuhin, Singh, Kanishk, Saakyan, Arkadiy, and Muresan, Smaranda
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Computer Science - Computation and Language ,Computer Science - Computer Vision and Pattern Recognition - Abstract
Natural language instructions are a powerful interface for editing the outputs of text-to-image diffusion models. However, several challenges need to be addressed: 1) underspecification (the need to model the implicit meaning of instructions) 2) grounding (the need to localize where the edit has to be performed), 3) faithfulness (the need to preserve the elements of the image not affected by the edit instruction). Current approaches focusing on image editing with natural language instructions rely on automatically generated paired data, which, as shown in our investigation, is noisy and sometimes nonsensical, exacerbating the above issues. Building on recent advances in segmentation, Chain-of-Thought prompting, and visual question answering, we significantly improve the quality of the paired data. In addition, we enhance the supervision signal by highlighting parts of the image that need to be changed by the instruction. The model fine-tuned on the improved data is capable of performing fine-grained object-centric edits better than state-of-the-art baselines, mitigating the problems outlined above, as shown by automatic and human evaluations. Moreover, our model is capable of generalizing to domains unseen during training, such as visual metaphors., Comment: Findings of EMNLP 2023 (Long paper)
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- 2023
17. NormDial: A Comparable Bilingual Synthetic Dialog Dataset for Modeling Social Norm Adherence and Violation
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Li, Oliver, Subramanian, Mallika, Saakyan, Arkadiy, CH-Wang, Sky, and Muresan, Smaranda
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Computer Science - Computation and Language ,Computer Science - Computers and Society - Abstract
Social norms fundamentally shape interpersonal communication. We present NormDial, a high-quality dyadic dialogue dataset with turn-by-turn annotations of social norm adherences and violations for Chinese and American cultures. Introducing the task of social norm observance detection, our dataset is synthetically generated in both Chinese and English using a human-in-the-loop pipeline by prompting large language models with a small collection of expert-annotated social norms. We show that our generated dialogues are of high quality through human evaluation and further evaluate the performance of existing large language models on this task. Our findings point towards new directions for understanding the nuances of social norms as they manifest in conversational contexts that span across languages and cultures., Comment: EMNLP 2023 Main Conference, Short Paper; Data at https://github.com/Aochong-Li/NormDial
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- 2023
18. Fractional order control for unstable first order processes with time delays
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Muresan, Cristina I. and Birs, Isabela
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- 2024
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19. Art or Artifice? Large Language Models and the False Promise of Creativity
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Chakrabarty, Tuhin, Laban, Philippe, Agarwal, Divyansh, Muresan, Smaranda, and Wu, Chien-Sheng
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Computer Science - Computation and Language ,Computer Science - Artificial Intelligence ,Computer Science - Human-Computer Interaction - Abstract
Researchers have argued that large language models (LLMs) exhibit high-quality writing capabilities from blogs to stories. However, evaluating objectively the creativity of a piece of writing is challenging. Inspired by the Torrance Test of Creative Thinking (TTCT), which measures creativity as a process, we use the Consensual Assessment Technique [3] and propose the Torrance Test of Creative Writing (TTCW) to evaluate creativity as a product. TTCW consists of 14 binary tests organized into the original dimensions of Fluency, Flexibility, Originality, and Elaboration. We recruit 10 creative writers and implement a human assessment of 48 stories written either by professional authors or LLMs using TTCW. Our analysis shows that LLM-generated stories pass 3-10X less TTCW tests than stories written by professionals. In addition, we explore the use of LLMs as assessors to automate the TTCW evaluation, revealing that none of the LLMs positively correlate with the expert assessments., Comment: ACM CHI 2024
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- 2023
20. Creativity Support in the Age of Large Language Models: An Empirical Study Involving Emerging Writers
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Chakrabarty, Tuhin, Padmakumar, Vishakh, Brahman, Faeze, and Muresan, Smaranda
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Computer Science - Human-Computer Interaction ,Computer Science - Artificial Intelligence ,Computer Science - Computation and Language ,Computer Science - Computers and Society - Abstract
The development of large language models (LLMs) capable of following instructions and engaging in conversational interactions sparked increased interest in their utilization across various support tools. We investigate the utility of modern LLMs in assisting professional writers via an empirical user study (n=30). The design of our collaborative writing interface is grounded in the cognitive process model of writing that views writing as a goal-oriented thinking process encompassing non-linear cognitive activities: planning, translating, and reviewing. Participants are asked to submit a post-completion survey to provide feedback on the potential and pitfalls of LLMs as writing collaborators. Upon analyzing the writer-LLM interactions, we find that while writers seek LLM's help across all three types of cognitive activities, they find LLMs more helpful in translation and reviewing. Our findings from analyzing both the interactions and the survey responses highlight future research directions in creative writing assistance using LLMs.
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- 2023
21. ICLEF: In-Context Learning with Expert Feedback for Explainable Style Transfer
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Saakyan, Arkadiy and Muresan, Smaranda
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Computer Science - Computation and Language - Abstract
While state-of-the-art large language models (LLMs) can excel at adapting text from one style to another, current work does not address the explainability of style transfer models. Recent work has explored generating textual explanations from larger teacher models and distilling them into smaller student models. One challenge with such approach is that LLM outputs may contain errors that require expertise to correct, but gathering and incorporating expert feedback is difficult due to cost and availability. To address this challenge, we propose ICLEF, a novel human-AI collaboration approach to model distillation that incorporates scarce expert human feedback by combining in-context learning and model self-critique. We show that our method leads to generation of high-quality synthetic explainable style transfer datasets for formality (e-GYAFC) and subjective bias (e-WNC). Via automatic and human evaluation, we show that specialized student models fine-tuned on our datasets outperform generalist teacher models on the explainable style transfer task in one-shot settings, and perform competitively compared to few-shot teacher models, highlighting the quality of the data and the role of expert feedback. In an extrinsic task of authorship attribution, we show that explanations generated by smaller models fine-tuned on e-GYAFC are more predictive of authorship than explanations generated by few-shot teacher models., Comment: ACL 2024 Main, Camera Ready
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- 2023
22. Hepatotoxicity induced by immune checkpoint inhibitors
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Flaviu Muresan, Olga Hilda Orasan, Angela Cozma, Madalina Daiana Bancos, Lorena Ciumarnean, Mircea Vasile Milaciu, Tinca Codruta Pocol, Nicoleta Valentina Leach, Teodora Gabriela Alexescu, Ovidiu Vasile Fabian, George Ciulei, and Mirela Georgiana Perne
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immune checkpoint inhibitors ,liver toxicity ,immunotherapy ,immune-related adverse events ,Medicine (General) ,R5-920 - Abstract
Immune checkpoint inhibitors (ICIs) are an effective immunotherapeutic approach for cancers affecting the lung, skin, kidney, mammary gland, or certain hematologic malignancies. Regarding the prognosis of these oncological conditions, treatments with ICIs open new therapeutic perspectives with benefits for both patients and healthcare providers. A drawback of immune checkpoint inhibition is the occurrence of immune-related adverse events that can involve a wide range of organs, such as the liver. Given widespread usage of immunotherapy, the number of patients who suffer from this unwanted condition has increased. Hepatopathy induced by ICIs can be severe and can even lead to death. Detecting liver toxicity in ICIs regiments requires a close monitorization of patients during and after the treatment. Such hepatopathies often involve discontinuation of immune checkpoint inhibitors and administration of corticosteroids. In conclusion, hepatopathies induced by immune checkpoint inhibitors require a comprehensive understanding for effective management, both to protect the patient's life during therapy and to ensure longer survival after cessation of treatment.
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- 2024
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23. Assessing semantic interoperability in environmental sciences: variety of approaches and semantic artefacts
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Di Muri, Cristina, Pulieri, Martina, Raho, Davide, Muresan, Alexandra N., Tarallo, Andrea, Titocci, Jessica, Nestola, Enrica, Basset, Alberto, Mazzoni, Sabrina, and Rosati, Ilaria
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- 2024
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24. Membranous urethral length is the single independent predictor of urinary continence recovery at 12 months following Retzius-sparing robot-assisted radical prostatectomy
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Fonseca, Jorge, Moraes-Fontes, Maria Francisca, Sousa, Inês, Oliveira, Francisco, Froes, Gonçalo, Gaivão, Ana, Palmas, Artur, Rebola, Jorge, Muresan, Ciprian, Santos, Tiago, Dias, Daniela, Varandas, Mário, Lopez-Beltran, Antonio, Ribeiro, Ricardo, and Fraga, Avelino
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- 2024
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25. Transcriptionally active chromatin loops contain both ‘active’ and ‘inactive’ histone modifications that exhibit exclusivity at the level of nucleosome clusters
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Koestler, Stefan A., Ball, Madeleine L., Muresan, Leila, Dinakaran, Vineet, and White, Robert
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- 2024
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26. Efficacy, Safety, and Tolerability of Doravirine/Lamivudine/Tenofovir Disoproxil Fumarate Fixed-Dose Combination Tablets in Adolescents Living With HIV: Results Through Week 96 from IMPAACT 2014
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Rungmaitree, Supattra, Aurpibul, Linda, Best, Brookie M, Li, Xiang, Warshaw, Meredith G, Wan, Hong, Tobin, Nicole H, Jumes, Patricia, Leavitt, Randi, McCarthy, Katie, Scheckter, Rachel, Ounchanum, Pradthana, Violari, Avy, Teppler, Hedy, Campbell, Havilland, Krotje, Chelsea, Townley, Ellen, Moye, Jack, Melvin, Ann J, Beck, Justine, Sise, Thucuma, Kapogiannis, Bill G, George, Kathleen, Morgan, Patricia, Woolwine-Cunningham, Yvonne, Leblanc, Rebecca, Trabert, Kathleen, Mendell, Jeanne, Alvero, Carmelita, Farhad, Mona, Pasyar, Sarah, Muresan, Petronella, Patel, Nehali, English, Adrienne, Heince, Ryan, Jones, Sandra, Cooper, Ellen, McLaud, Debra, McFarland, Elizabeth, Hays, Shane Curran, Dunn, Jennifer, Navarro, Kacey, Robson, Amanda, Ndiwani, Hilda, Mathiba, Ruth, Ramsagar, Nastassja, Chotirosniramit, Nuntisa, Khamrong, Chintana, Chantong, Jiraporn, Srita, Angkana, Cressey, Tim R, Sukrakanchana, Praornsuda, Kaewmamuang, Kanyanee, Thaweesombat, Yupawan, Vanprapar, Nirun, Chokephaibulkit, Kulkanya, Kongstan, Nantaka, and Lermankul, Watcharee
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Biomedical and Clinical Sciences ,Clinical Sciences ,HIV/AIDS ,Infectious Diseases ,Clinical Trials and Supportive Activities ,Clinical Research ,Pediatric ,Sexually Transmitted Infections ,6.1 Pharmaceuticals ,Infection ,Good Health and Well Being ,Adolescent ,Female ,Humans ,Male ,Anti-HIV Agents ,Anti-Retroviral Agents ,HIV Infections ,HIV Seropositivity ,Lamivudine ,RNA ,Tenofovir ,Treatment Outcome ,adolescents ,doravirine ,HIV-1 ,MK-1439A ,IMPAACT 2014 study team ,Medical microbiology ,Paediatrics - Abstract
BackgroundIMPAACT 2014 study is a phase I/II, multicenter, open-label, nonrandomized study of doravirine (DOR) co-formulated with lamivudine (3TC) and tenofovir disoproxil fumarate (TDF) as fixed-dose combination (DOR FDC) in adolescents with HIV-1. We report the efficacy, safety, and tolerability of DOR FDC through 96 weeks.MethodsParticipants were adolescents aged 12 to
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- 2023
27. I Spy a Metaphor: Large Language Models and Diffusion Models Co-Create Visual Metaphors
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Chakrabarty, Tuhin, Saakyan, Arkadiy, Winn, Olivia, Panagopoulou, Artemis, Yang, Yue, Apidianaki, Marianna, and Muresan, Smaranda
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Computer Science - Computation and Language ,Computer Science - Artificial Intelligence ,Computer Science - Computer Vision and Pattern Recognition ,Computer Science - Human-Computer Interaction - Abstract
Visual metaphors are powerful rhetorical devices used to persuade or communicate creative ideas through images. Similar to linguistic metaphors, they convey meaning implicitly through symbolism and juxtaposition of the symbols. We propose a new task of generating visual metaphors from linguistic metaphors. This is a challenging task for diffusion-based text-to-image models, such as DALL$\cdot$E 2, since it requires the ability to model implicit meaning and compositionality. We propose to solve the task through the collaboration between Large Language Models (LLMs) and Diffusion Models: Instruct GPT-3 (davinci-002) with Chain-of-Thought prompting generates text that represents a visual elaboration of the linguistic metaphor containing the implicit meaning and relevant objects, which is then used as input to the diffusion-based text-to-image models.Using a human-AI collaboration framework, where humans interact both with the LLM and the top-performing diffusion model, we create a high-quality dataset containing 6,476 visual metaphors for 1,540 linguistic metaphors and their associated visual elaborations. Evaluation by professional illustrators shows the promise of LLM-Diffusion Model collaboration for this task . To evaluate the utility of our Human-AI collaboration framework and the quality of our dataset, we perform both an intrinsic human-based evaluation and an extrinsic evaluation using visual entailment as a downstream task., Comment: ACL 2023 (Findings)
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- 2023
28. TOI-1130: A photodynamical analysis of a hot Jupiter in resonance with an inner low-mass planet
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Korth, J., Gandolfi, D., Šubjak, J., Howard, S., Ataiee, S., Collins, K. A., Quinn, S. N., Mustill, A. J., Guillot, T., Lodieu, N., Smith, A. M. S., Esposito, M., Rodler, F., Muresan, A., Abe, L., Albrecht, S. H., Alqasim, A., Barkaoui, K., Beck, P. G., Burke, C. J., Butler, R. P., Conti, D. M., Collins, K. I., Crane, J. D., Dai, F., Deeg, H. J., Evans, P., Grziwa, S., Hatzes, A. P., Hirano, T., Horne, K., Huang, C. X., Jenkins, J. M., Kabáth, P., Kielkopf, J. F., Knudstrup, E., Latham, D. W., Livingston, J., Luque, R., Mathur, S., Murgas, F., Osborne, H. L. M., Pallé, E., Persson, C. M., Rodriguez, J. E., Rose, M., Rowden, P., Schwarz, R. P., Seager, S., Serrano, L. M., Sha, L., Shectman, S. A., Shporer, A., Srdoc, G., Stockdale, C., Tan, T. G., Teske, J. K., Van Eylen, V., Vanderburg, A., Vanderspek, R., Wang, S. X., and Winn, J. N.
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Astrophysics - Earth and Planetary Astrophysics - Abstract
The TOI-1130 is a known planetary system around a K-dwarf consisting of a gas giant planet, TOI-1130 c, on an 8.4-day orbit, accompanied by an inner Neptune-sized planet, TOI-1130 b, with an orbital period of 4.1 days. We collected precise radial velocity (RV) measurements of TOI-1130 with the HARPS and PFS spectrographs as part of our ongoing RV follow-up program. We perform a photodynamical modeling of the HARPS and PFS RVs, and transit photometry from the Transiting Exoplanet Survey Satellite (TESS) and the TESS Follow-up Observing Program. We determine the planet masses and radii of TOI-1130 b and TOI-1130 c to be Mb = 19.28 $\pm$ 0.97 M$_\oplus$ and Rb = 3.56 $\pm$ 0.13 R$_\oplus$, and Mc = 325.59 $\pm$ 5.59 M$_\oplus$ and Rc = 13.32+1.55-1.41 R$_\oplus$, respectively. We spectroscopically confirm TOI-1130 b that was previously only validated. We find that the two planets orbit with small eccentricities in a 2:1 resonant configuration. This is the first known system with a hot Jupiter and an inner lower mass planet locked in a mean-motion resonance. TOI-1130 belongs to the small yet increasing population of hot Jupiters with an inner low-mass planet that challenges the pathway for hot Jupiter formation. We also detect a linear RV trend possibly due to the presence of an outer massive companion., Comment: 19 pages, Accepted to A&A
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- 2023
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29. Sociocultural Norm Similarities and Differences via Situational Alignment and Explainable Textual Entailment
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CH-Wang, Sky, Saakyan, Arkadiy, Li, Oliver, Yu, Zhou, and Muresan, Smaranda
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Computer Science - Computation and Language - Abstract
Designing systems that can reason across cultures requires that they are grounded in the norms of the contexts in which they operate. However, current research on developing computational models of social norms has primarily focused on American society. Here, we propose a novel approach to discover and compare descriptive social norms across Chinese and American cultures. We demonstrate our approach by leveraging discussions on a Chinese Q&A platform (Zhihu) and the existing SocialChemistry dataset as proxies for contrasting cultural axes, align social situations cross-culturally, and extract social norms from texts using in-context learning. Embedding Chain-of-Thought prompting in a human-AI collaborative framework, we build a high-quality dataset of 3,069 social norms aligned with social situations across Chinese and American cultures alongside corresponding free-text explanations. To test the ability of models to reason about social norms across cultures, we introduce the task of explainable social norm entailment, showing that existing models under 3B parameters have significant room for improvement in both automatic and human evaluation. Further analysis of cross-cultural norm differences based on our dataset shows empirical alignment with the social orientations framework, revealing several situational and descriptive nuances in norms across these cultures., Comment: EMNLP 2023 Main Conference (Long Paper)
- Published
- 2023
30. A Weak Supervision Approach for Few-Shot Aspect Based Sentiment
- Author
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Vacareanu, Robert, Varia, Siddharth, Halder, Kishaloy, Wang, Shuai, Paolini, Giovanni, John, Neha Anna, Ballesteros, Miguel, and Muresan, Smaranda
- Subjects
Computer Science - Computation and Language - Abstract
We explore how weak supervision on abundant unlabeled data can be leveraged to improve few-shot performance in aspect-based sentiment analysis (ABSA) tasks. We propose a pipeline approach to construct a noisy ABSA dataset, and we use it to adapt a pre-trained sequence-to-sequence model to the ABSA tasks. We test the resulting model on three widely used ABSA datasets, before and after fine-tuning. Our proposed method preserves the full fine-tuning performance while showing significant improvements (15.84% absolute F1) in the few-shot learning scenario for the harder tasks. In zero-shot (i.e., without fine-tuning), our method outperforms the previous state of the art on the aspect extraction sentiment classification (AESC) task and is, additionally, capable of performing the harder aspect sentiment triplet extraction (ASTE) task.
- Published
- 2023
31. Multitask Instruction-based Prompting for Fallacy Recognition
- Author
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Alhindi, Tariq, Chakrabarty, Tuhin, Musi, Elena, and Muresan, Smaranda
- Subjects
Computer Science - Computation and Language - Abstract
Fallacies are used as seemingly valid arguments to support a position and persuade the audience about its validity. Recognizing fallacies is an intrinsically difficult task both for humans and machines. Moreover, a big challenge for computational models lies in the fact that fallacies are formulated differently across the datasets with differences in the input format (e.g., question-answer pair, sentence with fallacy fragment), genre (e.g., social media, dialogue, news), as well as types and number of fallacies (from 5 to 18 types per dataset). To move towards solving the fallacy recognition task, we approach these differences across datasets as multiple tasks and show how instruction-based prompting in a multitask setup based on the T5 model improves the results against approaches built for a specific dataset such as T5, BERT or GPT-3. We show the ability of this multitask prompting approach to recognize 28 unique fallacies across domains and genres and study the effect of model size and prompt choice by analyzing the per-class (i.e., fallacy type) results. Finally, we analyze the effect of annotation quality on model performance, and the feasibility of complementing this approach with external knowledge., Comment: In Proceedings of the 2022 Conference on Empirical Methods in Natural Language Processing, pages 8172 - 8187
- Published
- 2023
32. Synchronous cervical sympathetic chain schwannoma, parathyroid adenoma and hypofunctional nodular goiter - a case report and literature review
- Author
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Flaviu Muresan, Alexandrina-Manuela Muresan, Gabriel-Emil Petre, Iacob Domsa, Vasile Ovidiu Fabian, and Olga Hilda Orasan
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parapharyngeal space tumor ,carotid body tumor ,paraganglioma ,cervical sympathetic chain schwannoma ,horner`s syndrome ,vagal schwannoma ,Medicine (General) ,R5-920 - Abstract
Simultaneously diagnosing cervical sympathetic chain schwannoma, nodular goiter and parathyroid adenoma is a very rare event during clinical practice. We had the opportunity to find this unusual association on a female patient. While nodular goiter and parathyroid adenoma are more common diseases and easier to diagnose, identifying the etiology of a parapharyngeal space tumor remains a challenge and requires multiple imaging studies such as computed tomography scan, magnetic resonance imaging or angiography. A cervical sympathetic chain schwannoma, a carotid body tumor, a paraganglioma or a vagal schwannoma must be taken into account as possible diagnostic variants. Complaints such as Horner`s syndrome, hoarse voice or dysphagia may suggest a nerve originating tumor, but this is a rare situation. Only the surgical exploration is successful in detecting the tumor origin from the cervical sympathetic chain. Even so, the exact origin of the tumor cannot usually be detected without surgical exploration and removal of the piece or biopsies. Therefore, the pathological report of the specimen (adding or not immunohistochemistry tests) is mandatory to be able to confirm the diagnosis of schwannoma.
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- 2024
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33. Acute Calculous Cholecystitis Associated with Leptospirosis: Which is the Emergency? A Case Report and Literature Review
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Moriczi Renata, Muresan Mircea Gabriel, Neagoe Radu, Sala Daniela, Torok Arpad, Bara Tivadar, Balmos Ioan Alexandru, Ion Razvan, and Vasiesiu Anca Meda
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leptospirosis ,acute cholecystitis ,gallbladder stones ,weil's disease ,Medical emergencies. Critical care. Intensive care. First aid ,RC86-88.9 - Abstract
Leptospirosis is a bacterium with a worldwide distribution and belongs to the group of zoonoses that can affect both humans and animals. Most cases of leptospirosis present as a mild, anicteric infection. However, a small percentage of cases develop Weil’s disease, characterized by bleeding and elevated levels of bilirubin and liver enzymes. It can also cause inflammation of the gallbladder. Acute acalculous cholecystitis has been described as a manifestation of leptospirosis in a small percentage of cases; however, no association between leptospirosis and acute acalculous cholecystitis has been found in the literature.
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- 2024
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34. HD 20329b: An ultra-short-period planet around a solar-type star found by TESS
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Murgas, F., Nowak, G., Masseron, T., Parviainen, H., Luque, R., Pallé, E., Korth, Judith, Carleo, I., Csizmadia, Sz., Esparza-Borges, E., Alqasim, Ahlam, Cochran, William D., Dai, Fei, Deeg, Hans J., Gandolfi, D., Goffo, Elisa, Kabáth, Petr, Lam, K. W. F., Livingston, John, Muresan, Alexandra, Osborne, H. L. M., Persson, Carina M., Serrano, L. M., Smith, Alexis M. S., Van Eylen, Vincent, Orell-Miquel, J., Hinkel, Natalie R., Galán, D., Puig-Subirà, M., Stangret, M., Fukui, A., Kagetani, T., Narita, N., Ciardi, David R., Boyle, Andrew W., Ziegler, Carl, Briceño, César, Law, Nicholas, Mann, Andrew W., Jenkins, Jon M., Latham, David W., Quinn, Samuel N., Ricker, G., Seager, S., Shporer, Avi, Ting, Eric B., Vanderspek, R., and Winn, Joshua N.
- Subjects
Astrophysics - Earth and Planetary Astrophysics ,Astrophysics - Solar and Stellar Astrophysics - Abstract
We used TESS light curves and HARPS-N spectrograph radial velocity measurements to establish the physical properties of the transiting exoplanet candidate found around the star HD 20329 (TOI-4524). We performed a joint fit of the light curves and radial velocity time series to measure the mass, radius, and orbital parameters of the candidate. We confirm and characterize HD 20329b, an ultra-short-period (USP) planet transiting a solar-type star. The host star (HD 20329, $V = 8.74$ mag, $J = 7.5$ mag) is characterized by its G5 spectral type with $\mathrm{M}_\star= 0.90 \pm 0.05$ M$_\odot$, $\mathrm{R}_\star = 1.13 \pm 0.02$ R$_\odot$, and $\mathrm{T}_{\mathrm{eff}} = 5596 \pm 50$ K; it is located at a distance $d= 63.68 \pm 0.29$ pc. By jointly fitting the available TESS transit light curves and follow-up radial velocity measurements, we find an orbital period of $0.9261 \pm (0.5\times 10^{-4})$ days, a planetary radius of $1.72 \pm 0.07$ $\mathrm{R}_\oplus$, and a mass of $7.42 \pm 1.09$ $\mathrm{M}_\oplus$, implying a mean density of $\rho_\mathrm{p} = 8.06 \pm 1.53$ g cm$^{-3}$. HD 20329b joins the $\sim$30 currently known USP planets with radius and Doppler mass measurements., Comment: Accepted for publication in A&A, 26 pages
- Published
- 2022
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35. HD 191939 revisited: New and refined planet mass determinations, and a new planet in the habitable zone
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Orell-Miquel, J., Nowak, G., Murgas, F., Palle, E., Morello, G., Luque, R., Badenas-Agusti, M., Ribas, I., Lafarga, M., Espinoza, N., Morales, J. C., Zechmeister, M., Alqasim, A., Cochran, W. D., Gandolfi, D., Goffo, E., Kabáth, P., Korth, J., Livingston, J., Lam, K. W. F., Muresan, A., Persson, C. M., and Van Eylen, V.
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Astrophysics - Earth and Planetary Astrophysics - Abstract
HD 191939 (TOI-1339) is a nearby (d=54pc), bright (V=9mag), and inactive Sun-like star (G9 V) known to host a multi-planet transiting system. Ground-based spectroscopic observations confirmed the planetary nature of the three transiting sub-Neptunes (HD 191939 b, c, and d) originally detected by TESS and were used to measure the masses for planets b and c with 3$\sigma$ precision. These previous observations also reported the discovery of an additional Saturn-mass planet (HD 191939 e) and evidence for a further, very long-period companion (HD 191939 f). Here, we report the discovery of a new non-transiting planet in the system and a refined mass determination of HD 191939 d. The new planet, HD 191939 g, has a minimum mass of 13.5$\pm$2.0 M$_\oplus$ and a period of about 280 d. This period places the planet within the conservative habitable zone of the host star, and near a 1:3 resonance with HD 191939 e. The compilation of 362 radial velocity measurements with a baseline of 677 days from four different high-resolution spectrographs also allowed us to refine the properties of the previously known planets, including a 4.6$\sigma$ mass determination for planet d, for which only a 2$\sigma$ upper limit had been set until now. We confirm the previously suspected low density of HD 191939 d, which makes it an attractive target for attempting atmospheric characterisation. Overall, the planetary system consists of three sub-Neptunes interior to a Saturn-mass and a Uranus-mass planet plus a high-mass long-period companion. This particular configuration has no counterpart in the literature and makes HD 191939 an exceptional multi-planet transiting system with an unusual planet demographic worthy of future observation., Comment: Accepted for publication in A&A. 20 pages, 8 figures
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- 2022
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- View/download PDF
36. CONSISTENT: Open-Ended Question Generation From News Articles
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Chakrabarty, Tuhin, Lewis, Justin, and Muresan, Smaranda
- Subjects
Computer Science - Computation and Language - Abstract
Recent work on question generation has largely focused on factoid questions such as who, what, where, when about basic facts. Generating open-ended why, how, what, etc. questions that require long-form answers have proven more difficult. To facilitate the generation of open-ended questions, we propose CONSISTENT, a new end-to-end system for generating open-ended questions that are answerable from and faithful to the input text. Using news articles as a trustworthy foundation for experimentation, we demonstrate our model's strength over several baselines using both automatic and human=based evaluations. We contribute an evaluation dataset of expert-generated open-ended questions.We discuss potential downstream applications for news media organizations., Comment: EMNLP 2022 Findings
- Published
- 2022
37. TOI-969: a late-K dwarf with a hot mini-Neptune in the desert and an eccentric cold Jupiter
- Author
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Lillo-Box, J., Gandolfi, D., Armstrong, D. J., Collins, K. A., Nielsen, L. D., Luque, R., Korth, J., Sousa, S. G., Quinn, S. N., Acuña, L., Howell, S. B., Morello, G., Hellier, C., Giacalone, S., Hoyer, S., Stassun, K., Palle, E., Aguichine, A., Mousis, O., Adibekyan, V., Silva, T. Azevedo, Barrado, D., Deleuil, M., Eastman, J. D., Hawthorn, F., Irwin, J. M., Jenkins, J. M., Latham, D. W., Muresan, A., Persson, C. M., Santerne, A., Santos, N. C., Savel, A. B., Osborn, H. P., Teske, J., Wheatley, P. J., Winn, J. N., Barros, S. C. C., Butler, R. P., Caldwell, D. A., Charbonneau, D., Cloutier, R., Crane, J. D., Demangeon, O. D. S., Díaz, R. F., Dumusque, X., Esposito, M., Falk, B., Gill, H., Hojjatpanah, S., Kreidberg, L., Mireles, I., Osborn, A., Ricker, G. R., Rodriguez, J. E., Schwarz, R. P., Seager, S., Bell, J. Serrano, Shectman, S. A., Shporer, A., Vezie, M., Wang, S. X., and Zhou, G.
- Subjects
Astrophysics - Earth and Planetary Astrophysics - Abstract
The current architecture of a given multi-planetary system is a key fingerprint of its past formation and dynamical evolution history. Long-term follow-up observations are key to complete their picture. In this paper we focus on the confirmation and characterization of the components of the TOI-969 planetary system, where TESS detected a Neptune-size planet candidate in a very close-in orbit around a late K-dwarf star. We use a set of precise radial velocity observations from HARPS, PFS and CORALIE instruments covering more than two years in combination with the TESS photometric light curve and other ground-based follow-up observations to confirm and characterize the components of this planetary system. We find that TOI-969 b is a transiting close-in ($P_b\sim 1.82$ days) mini-Neptune planet ($m_b=9.1^{+1.1}_{-1.0}$ M$_{\oplus}$, $R_b=2.765^{+0.088}_{-0.097}$ R$_{\oplus}$), thus placing it on the {lower boundary} of the hot-Neptune desert ($T_{\rm eq,b}=941\pm31$ K). The analysis of its internal structure shows that TOI-969 b is a volatile-rich planet, suggesting it underwent an inward migration. The radial velocity model also favors the presence of a second massive body in the system, TOI-969 c, with a long period of $P_c=1700^{+290}_{-280}$ days and a minimum mass of $m_{c}\sin{i_c}=11.3^{+1.1}_{-0.9}$ M$_{\rm Jup}$, and with a highly-eccentric orbit of $e_c=0.628^{+0.043}_{-0.036}$. The TOI-969 planetary system is one of the few around K-dwarfs known to have this extended configuration going from a very close-in planet to a wide-separation gaseous giant. TOI-969 b has a transmission spectroscopy metric of 93, and it orbits a moderately bright ($G=11.3$ mag) star, thus becoming an excellent target for atmospheric studies. The architecture of this planetary system can also provide valuable information about migration and formation of planetary systems., Comment: Accepted for publication in A&A. 25 pages, 15 figures, 12 tables
- Published
- 2022
- Full Text
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38. Affective Idiosyncratic Responses to Music
- Author
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CH-Wang, Sky, Li, Evan, Li, Oliver, Muresan, Smaranda, and Yu, Zhou
- Subjects
Computer Science - Computation and Language ,Computer Science - Artificial Intelligence ,Computer Science - Computers and Society ,Computer Science - Sound ,Electrical Engineering and Systems Science - Audio and Speech Processing - Abstract
Affective responses to music are highly personal. Despite consensus that idiosyncratic factors play a key role in regulating how listeners emotionally respond to music, precisely measuring the marginal effects of these variables has proved challenging. To address this gap, we develop computational methods to measure affective responses to music from over 403M listener comments on a Chinese social music platform. Building on studies from music psychology in systematic and quasi-causal analyses, we test for musical, lyrical, contextual, demographic, and mental health effects that drive listener affective responses. Finally, motivated by the social phenomenon known as w\v{a}ng-y\`i-y\'un, we identify influencing factors of platform user self-disclosures, the social support they receive, and notable differences in discloser user activity., Comment: EMNLP 2022 Main Conference; see Github https://github.com/skychwang/music-emotions
- Published
- 2022
39. NormSAGE: Multi-Lingual Multi-Cultural Norm Discovery from Conversations On-the-Fly
- Author
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Fung, Yi R., Chakraborty, Tuhin, Guo, Hao, Rambow, Owen, Muresan, Smaranda, and Ji, Heng
- Subjects
Computer Science - Computation and Language ,Computer Science - Artificial Intelligence - Abstract
Norm discovery is important for understanding and reasoning about the acceptable behaviors and potential violations in human communication and interactions. We introduce NormSage, a framework for addressing the novel task of conversation-grounded multi-lingual, multi-cultural norm discovery, based on language model prompting and self-verification. NormSAGE leverages the expressiveness and implicit knowledge of the pretrained GPT-3 language model backbone, to elicit knowledge about norms through directed questions representing the norm discovery task and conversation context. It further addresses the risk of language model hallucination with a self-verification mechanism ensuring that the norms discovered are correct and are substantially grounded to their source conversations. Evaluation results show that our approach discovers significantly more relevant and insightful norms for conversations on-the-fly compared to baselines (>10+% in Likert scale rating). The norms discovered from Chinese conversation are also comparable to the norms discovered from English conversation in terms of insightfulness and correctness (<3% difference). In addition, the culture-specific norms are promising quality, allowing for 80% accuracy in culture pair human identification. Finally, our grounding process in norm discovery self-verification can be extended for instantiating the adherence and violation of any norm for a given conversation on-the-fly, with explainability and transparency. NormSAGE achieves an AUC of 95.4% in grounding, with natural language explanation matching human-written quality.
- Published
- 2022
40. Instruction Tuning for Few-Shot Aspect-Based Sentiment Analysis
- Author
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Varia, Siddharth, Wang, Shuai, Halder, Kishaloy, Vacareanu, Robert, Ballesteros, Miguel, Benajiba, Yassine, John, Neha Anna, Anubhai, Rishita, Muresan, Smaranda, and Roth, Dan
- Subjects
Computer Science - Computation and Language - Abstract
Aspect-based Sentiment Analysis (ABSA) is a fine-grained sentiment analysis task which involves four elements from user-generated texts: aspect term, aspect category, opinion term, and sentiment polarity. Most computational approaches focus on some of the ABSA sub-tasks such as tuple (aspect term, sentiment polarity) or triplet (aspect term, opinion term, sentiment polarity) extraction using either pipeline or joint modeling approaches. Recently, generative approaches have been proposed to extract all four elements as (one or more) quadruplets from text as a single task. In this work, we take a step further and propose a unified framework for solving ABSA, and the associated sub-tasks to improve the performance in few-shot scenarios. To this end, we fine-tune a T5 model with instructional prompts in a multi-task learning fashion covering all the sub-tasks, as well as the entire quadruple prediction task. In experiments with multiple benchmark datasets, we show that the proposed multi-task prompting approach brings performance boost (by absolute 8.29 F1) in the few-shot learning setting., Comment: Camera ready copy for WASSA at ACL 2023
- Published
- 2022
41. BigNeuron: a resource to benchmark and predict performance of algorithms for automated tracing of neurons in light microscopy datasets
- Author
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Manubens-Gil, Linus, Zhou, Zhi, Chen, Hanbo, Ramanathan, Arvind, Liu, Xiaoxiao, Liu, Yufeng, Bria, Alessandro, Gillette, Todd, Ruan, Zongcai, Yang, Jian, Radojević, Miroslav, Zhao, Ting, Cheng, Li, Qu, Lei, Liu, Siqi, Bouchard, Kristofer E, Gu, Lin, Cai, Weidong, Ji, Shuiwang, Roysam, Badrinath, Wang, Ching-Wei, Yu, Hongchuan, Sironi, Amos, Iascone, Daniel Maxim, Zhou, Jie, Bas, Erhan, Conde-Sousa, Eduardo, Aguiar, Paulo, Li, Xiang, Li, Yujie, Nanda, Sumit, Wang, Yuan, Muresan, Leila, Fua, Pascal, Ye, Bing, He, Hai-yan, Staiger, Jochen F, Peter, Manuel, Cox, Daniel N, Simonneau, Michel, Oberlaender, Marcel, Jefferis, Gregory, Ito, Kei, Gonzalez-Bellido, Paloma, Kim, Jinhyun, Rubel, Edwin, Cline, Hollis T, Zeng, Hongkui, Nern, Aljoscha, Chiang, Ann-Shyn, Yao, Jianhua, Roskams, Jane, Livesey, Rick, Stevens, Janine, Liu, Tianming, Dang, Chinh, Guo, Yike, Zhong, Ning, Tourassi, Georgia, Hill, Sean, Hawrylycz, Michael, Koch, Christof, Meijering, Erik, Ascoli, Giorgio A, and Peng, Hanchuan
- Subjects
Biological Sciences ,Networking and Information Technology R&D (NITRD) ,Bioengineering ,Machine Learning and Artificial Intelligence ,Benchmarking ,Microscopy ,Imaging ,Three-Dimensional ,Neurons ,Algorithms ,Technology ,Medical and Health Sciences ,Developmental Biology ,Biological sciences - Abstract
BigNeuron is an open community bench-testing platform with the goal of setting open standards for accurate and fast automatic neuron tracing. We gathered a diverse set of image volumes across several species that is representative of the data obtained in many neuroscience laboratories interested in neuron tracing. Here, we report generated gold standard manual annotations for a subset of the available imaging datasets and quantified tracing quality for 35 automatic tracing algorithms. The goal of generating such a hand-curated diverse dataset is to advance the development of tracing algorithms and enable generalizable benchmarking. Together with image quality features, we pooled the data in an interactive web application that enables users and developers to perform principal component analysis, t-distributed stochastic neighbor embedding, correlation and clustering, visualization of imaging and tracing data, and benchmarking of automatic tracing algorithms in user-defined data subsets. The image quality metrics explain most of the variance in the data, followed by neuromorphological features related to neuron size. We observed that diverse algorithms can provide complementary information to obtain accurate results and developed a method to iteratively combine methods and generate consensus reconstructions. The consensus trees obtained provide estimates of the neuron structure ground truth that typically outperform single algorithms in noisy datasets. However, specific algorithms may outperform the consensus tree strategy in specific imaging conditions. Finally, to aid users in predicting the most accurate automatic tracing results without manual annotations for comparison, we used support vector machine regression to predict reconstruction quality given an image volume and a set of automatic tracings.
- Published
- 2023
42. Anesthesia Control Using Fractional Order Controller.
- Author
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Eva-Henrietta Dulf, Paul-Andrei Pintea, and Cristina I. Muresan
- Published
- 2024
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43. Connecting the Dots: Evaluating Abstract Reasoning Capabilities of LLMs Using the New York Times Connections Word Game.
- Author
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Prisha Samadarshi, Mariam Mustafa, Anushka Kulkarni, Raven Rothkopf, Tuhin Chakrabarty, and Smaranda Muresan
- Published
- 2024
44. Identifying Self-Disclosures of Use, Misuse and Addiction in Community-based Social Media Posts.
- Author
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Chenghao Yang, Tuhin Chakrabarty, Karli R. Hochstatter, Melissa N. Slavin, Nabila El-Bassel, and Smaranda Muresan
- Published
- 2024
- Full Text
- View/download PDF
45. Uncertainty and its Effect on Optimal Multidrug Control of Hemodynamic Variables.
- Author
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Teodora Popescu, Isabela Roxana Birs, Ghada Ben Othman, Erhan Yumuk, Marcian Mihai, Erwin Hegedus, Dana Copot, Robin De Keyser, Clara M. Ionescu, and Cristina I. Muresan
- Published
- 2024
- Full Text
- View/download PDF
46. Experimental Validation of a Fractional Order Autotuner for a Two Rotor Aerodynamical System.
- Author
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Cristina I. Muresan, Marcian Mihai, Erwin Hegedus, Elisabeta Kozma, and Isabela Roxana Birs
- Published
- 2024
- Full Text
- View/download PDF
47. ICLEF: In-Context Learning with Expert Feedback for Explainable Style Transfer.
- Author
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Arkadiy Saakyan and Smaranda Muresan
- Published
- 2024
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- View/download PDF
48. Large Language Models are Few-Shot Training Example Generators: A Case Study in Fallacy Recognition.
- Author
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Tariq Alhindi, Smaranda Muresan, and Preslav Nakov
- Published
- 2024
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49. Creativity Support in the Age of Large Language Models: An Empirical Study Involving Professional Writers.
- Author
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Tuhin Chakrabarty, Vishakh Padmakumar, Faeze Brahman, and Smaranda Muresan
- Published
- 2024
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50. Adapting Supervised Machine Learning for Analysis of Neurobiological Signals.
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Andrei Ciuparu, Ann Christin Garvert, Koen Gerard Alois Vervaeke, and Raul Cristian Muresan
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- 2024
- Full Text
- View/download PDF
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