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Extra-cellular galectins 1, 3 and 9 (gal-1, -3 and -9) are known to act as soluble immunosuppressive agents in various malignancies. Previous publications have suggested that their expression is dependent on the metabolic status of producing cells and reciprocally that they can influence metabolic pathways in their target cells. Very little is known about the status of gal-1, -3 and -9 in patients bearing head and neck squamous cell carcinomas (HNSCC) and about their relationships with the systemic metabolic condition. This study was conducted in plasma samples from a prospective cohort of 83 HNSCC patients with advanced disease. These samples were used to explore the distribution of gal-1, -3 and -9 and simultaneously to profile a series of 87 metabolites assessed by mass spectrometry. We identified galectin and metabolic patterns within five disease categories defined according to the primary site and human papillomavirus (HPV) status (HPV-positive and -negative oropharyngeal carcinomas, carcinomas of the oral cavity, hypopharynx and larynx carcinomas). Remarkably, samples related to hypopharyngeal carcinomas displayed the highest average concentration of gal-9 (

Una idea resume lo que hemos aprendido en la Universidad de los niños EAFIT sobre hacer programas de comunicación de la ciencia en radio: un buen programa de radio es un taller educativo sonoro. Tanto el taller como el programa se basan en la diversidad como elemento enriquecedor, la ausencia de jerarquías respecto al conocimiento y la pregunta como puerta a la conversación y el intercambio de saberes., At EAFIT Children's University we have learnt that a good science radio show resembles an educational workshop. In the program, both workshop and radio shows are based on diversity as an enriching element, the absence of hierarchies regarding knowledge and the question as a door to conversation and the exchange of knowledge.

Las universidades de los niños son programas de comunicación y educación de la ciencia que comenzaron en la primera década del siglo XXI en Austria y Alemania. Hoy, existen más de 70 programas en Alemania y 400 en el mundo que acogen esta noción expandida de universidad, donde los niños y las niñas son interlocutores legítimos en la construcción del conocimiento., Children's universities are science education and communication programs around the world that started in the first decade of the twenty first century in Austria and Germany.

The cartoon of the science communication monster was used by various researchers to name the things that must have someone who wants to be a communicator of science using the parts of his body as dog snout, feet like amphibian, lint as phosphor sticks and thus get the best monster, La caricatura del monstruo divulgador la utilizaron diversos investigadores para nombrar las cosas que debe tener alguien que quiera ser comunicador de la ciencia utilizando las partes de su cuerpo como hocico de perro, pies como de anfibio, pelusas como palitos de fosforo y así obtener al mejor monstruo divulgador

When asked: How can science and technology contribute to Colombia's problems today? Various characters from sectors such as childhood, academia, youth, among others, express their point of view, although they agree that science is important because it allows them to know about different topics and understand why things., Ante la pregunta: ¿Cómo pueden la ciencia y la tecnología contribuir a los problemas de Colombia en la actualidad? Diversos personajes de sectores como la infancia, la academia, la juventud, entre otros, expresan su punto de vista, aunque coinciden en que la ciencia es importante porque les permite conocer de diferentes temas y entender el porque de las cosas.

The editor of the virtual encyclopedia, Wikipedia, Juan Sebastián recounts his experience and work with Wikipedia that has become his passion coming out of the spontaneity of wanting topics of his interest on the web to be found. There is also very good data from the members of this community from their roles to page figures as such and their alliances. El editor de la enciclopedia virtual, Wikipedia, Juan Sebastián relata su experiencia y trabajo con Wikipedia que se ha convertido en su pasión saliendo de la espontaneidad de querer que se encontraran temas de su interés en la web. También se encuentran unos muy buenos datos de los integrantes de esta comunidad desde sus roles hasta cifras de las páginas como tal y sus alianzas.

The editor of the virtual encyclopedia, Wikipedia, Juan Sebastián recounts his experience and work with Wikipedia that has become his passion coming out of the spontaneity of wanting topics of his interest on the web to be found. There is also very good data from the members of this community from their roles to page figures as such and their alliances., El editor de la enciclopedia virtual, Wikipedia, Juan Sebastián relata su experiencia y trabajo con Wikipedia que se ha convertido en su pasión saliendo de la espontaneidad de querer que se encontraran temas de su interés en la web. También se encuentran unos muy buenos datos de los integrantes de esta comunidad desde sus roles hasta cifras de las páginas como tal y sus alianzas.

Literature is the way Angela Posada Swafford communicates science, she is convinced that it is easier to learn with a story than with a lot of data, so she not only describes from her point of view, but also from beings who interact in the environment., La literatura es la forma en como Ángela Posada Swafford comunica la ciencia, está convencida de que es más fácil aprender con un cuento que con un montón de datos, por eso no solo describe desde su punto de vista, sino también desde los seres que interactúan en el entorno.

UNAM is a Mexican university that has integrated research and the extension of culture. This university has traveled the path of scientific dissemination that today allows it to be in charge of the Directorate, two museums, media and academic publications. Director Elaine Reynoso counts more of these processes. UNAM es una universidad mexicana que ha integrado la investigación y la extensión de la cultura. Esta universidad ha recorrido el camino de la divulgación científica que hoy le permite tener a cargo de la Dirección, dos museos, medios de comunicación y publicaciones académicas. La directora Elaine Reynoso cuenta más de estos procesos.

Endoglycan is a CD34-related sialomucin proposed to play a role in selectin-dependent adhesion of leukocytes to vasculature. Here we have investigated the distribution and function of endoglycan by generating a specific monoclonal antibody to an extracellular epitope of the protein. On non-hematopoietic cells, endoglycan is a relatively selective marker of smooth muscle cells of the gut, airway, and vasculature. Surprisingly, endoglycan does not appear to be a marker of vascular endothelia. Within the mature lineages of the hematopoietic system, endoglycan is restricted to a subset of CD4+CD8+ thymocytes and a subset of mature peripheral B cells. In the spleen of naïve mice, the highest levels of endoglycan surface expression is on marginal zone B (MZB) cells with much lower expression on follicular B cells. To further explore the regulation of endoglycan expression we treated splenocytes with a panel of toll-like receptor (TLR) ligands and cytokines. LPS, Pam3CSK4, CpG and IL-1 all enhanced endoglycan surface expression on splenic B cells approximately four-fold within 48 hrs. Interestingly, TLR ligand-dependent upregulation was blocked in the presence of IL-4, IL-5 or TGF-β, suggesting a selective requirement for endoglycan in T cell independent responses. This work was funded by an operating grant from the Heart and Stroke Foundation of Canada. EJF is a recipient of an NSERC post-graduate scholarship.