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377 results on '"Murphy, G. J."'

1. Quantum groups, differential calculi and the eigenvalues of the Laplacian

Author

Kustermans, J., Murphy, G. J., and Tuset, L.

Subjects
Mathematics - Quantum Algebra, 58B32, 58B34
Abstract

We study *-differential calculi over compact quantum groups in the sense of S.L. Woronowicz. Our principal results are the construction of a Hodge operator commuting with the Laplacian, the derivation of a corresponding Hodge decomposition of the calculus of forms, and, for Woronowicz' first calculus, the calculation of the eigenvalues of the Laplacian, Comment: 39 pages, LaTeX2e

Published
2001

2. Amenability and co-amenability of algebraic quantum groups

Author

Bedos, E., Murphy, G. J., and Tuset, L.

Subjects
Mathematics - Operator Algebras, 46L05, 46L65, 22D25
Abstract

We define concepts of amenability and co-amenability for algebraic quantum groups in the sense of A. Van Daele. We show that co-amenability of an algebraic quantum group always implies amenability of its dual. Various necessary and/or sufficient conditions for amenability or co-amenability are obtained. Co-amenability is shown to have interesting consequences for the modular theory in the case that the algebraic quantum group is of compact type., Comment: 25 pages, with some minor corrections, as to appear in the IJMMS

Published
2001

3. Amenability and co-amenability of algebraic quantum groups II

Author

Bedos, E., Murphy, G. J., and Tuset, L.

Subjects
Mathematics - Operator Algebras, 46L05, 46L65, 22D25
Abstract

We continue our study of the concepts of amenability and co-amenability for algebraic quantum groups in the sense of A. Van Daele and our investigation of their relationship with nuclearity and injectivity. One major tool for our analysis is that every non-degenerate *-representation of the universal C*-algebra associated to an algebraic quantum qroup has a unitary generator which may be described in a concrete way., Comment: 34 pages

Published
2001

4. Differential Calculi over Quantum Groups and Twisted Cyclic Cocycles

Author

Kustermans, J., Murphy, G. J., and Tuset, L.

Subjects
Mathematics - Quantum Algebra, 46L, 81R50
Abstract

We study some aspects of the theory of non-commutative differential calculi over complex algebras, especially over the Hopf algebras associated to compact quantum groups in the sense of S.L. Woronowicz. Our principal emphasis is on the theory of twisted graded traces and their associated twisted cyclic cocycles. One of our principal results is a new method of constructing differential calculi, using twisted graded traces., Comment: changes in layout

Published
2001

15. Pre‐operative and prehabilitation services in UK cardiac surgery centres.

Author

Gibbison, B., Murphy, G. J., Akowuah, E., Loubani, M., and Pufulete, M.

Subjects
*CARDIAC surgery, *PREHABILITATION, *ELECTIVE surgery
Abstract

Cardiac surgery has two distinct treatment pathways; approximately half of the 32,000 adult cardiac surgery episodes in the UK per year are planned (mean waiting time of 104 days) and half are urgent inpatients (mean waiting time of 11 days), plus a small number of emergency cases [[3]]. Prehabilitation is the practice of enhancing a patient's functional capacity before surgery, with the aim of improving postoperative outcomes [[1]]. 1 Table Pre-operative assessment (POA) service and prehabilitation components in urgent and elective cardiac surgery pathways from 34 cardiac surgery centres. [Extracted from the article]

Published
2023
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16. The association between iron deficiency and outcomes: a secondary analysis of the intravenous iron therapy to treat iron deficiency anaemia in patients undergoing major abdominal surgery (PREVENTT) trial.

Author

Richards, T., Miles, L. F., Clevenger, B., Keegan, A., Abeysiri, S., Rao Baikady, R., Besser, M. W., Browne, J. P., Klein, A. A., Macdougall, I. C., Murphy, G. J., Anker, S. D., Dahly, D., Richards, Toby, Besser, Martin, Browne, John, Clevenger, Ben, Kegan, Anastazia, Klein, Andrew, and Miles, Lachlan

Subjects
IRON deficiency anemia, IRON deficiency, INTRAVENOUS therapy, ABDOMINAL surgery, SECONDARY analysis, RED blood cell transfusion
Abstract

Summary: In the intravenous iron therapy to treat iron deficiency anaemia in patients undergoing major abdominal surgery (PREVENTT) trial, the use of intravenous iron did not reduce the need for blood transfusion or reduce patient complications or length of hospital stay. As part of the trial protocol, serum was collected at randomisation and on the day of surgery. These samples were analysed in a central laboratory for markers of iron deficiency. We performed a secondary analysis to explore the potential interactions between pre‐operative markers of iron deficiency and intervention status on the trial outcome measures. Absolute iron deficiency was defined as ferritin <30 μg.l−1; functional iron deficiency as ferritin 30–100 μg.l−1 or transferrin saturation < 20%; and the remainder as non‐iron deficient. Interactions were estimated using generalised linear models that included different subgroup indicators of baseline iron status. Co‐primary endpoints were blood transfusion or death and number of blood transfusions, from randomisation to 30 days postoperatively. Secondary endpoints included peri‐operative change in haemoglobin, postoperative complications and length of hospital stay. Most patients had iron deficiency (369/452 [82%]) at randomisation; one‐third had absolute iron deficiency (144/452 [32%]) and half had functional iron deficiency (225/452 [50%]). The change in pre‐operative haemoglobin with intravenous iron compared with placebo was greatest in patients with absolute iron deficiency, mean difference 8.9 g.l−1, 95%CI 5.3–12.5; moderate in functional iron deficiency, mean difference 2.8 g.l−1, 95%CI −0.1 to 5.7; and with little change seen in those patients who were non‐iron deficient. Subgroup analyses did not suggest that intravenous iron compared with placebo reduced the likelihood of death or blood transfusion at 30 days differentially across subgroups according to baseline ferritin (p = 0.33 for interaction), transferrin saturation (p = 0.13) or in combination (p = 0.45), or for the number of blood transfusions (p = 0.06, 0.29, and 0.39, respectively). There was no beneficial effect of the use of intravenous iron compared with placebo, regardless of the metrics to diagnose iron deficiency, on postoperative complications or length of hospital stay. [ABSTRACT FROM AUTHOR]

Published
2023
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20. Transfusion strategies in non-bleeding critically ill adults: a clinical practice guideline from the European Society of Intensive Care Medicine

Author

Vlaar, A. P., Oczkowski, S., de Bruin, S., Wijnberge, M., Antonelli, Massimo, Aubron, C., Aries, P., Duranteau, J., Juffermans, N. P., Meier, J., Murphy, G. J., Abbasciano, R., Muller, M., Shah, A., Perner, A., Rygaard, S., Walsh, T. S., Guyatt, G., Dionne, J. C., Cecconi, M., Antonelli M. (ORCID:0000-0003-3007-1670), Vlaar, A. P., Oczkowski, S., de Bruin, S., Wijnberge, M., Antonelli, Massimo, Aubron, C., Aries, P., Duranteau, J., Juffermans, N. P., Meier, J., Murphy, G. J., Abbasciano, R., Muller, M., Shah, A., Perner, A., Rygaard, S., Walsh, T. S., Guyatt, G., Dionne, J. C., Cecconi, M., and Antonelli M. (ORCID:0000-0003-3007-1670)

Abstract

Objective: To develop evidence-based clinical practice recommendations regarding transfusion practices in non-bleeding, critically ill adults. Design: A task force involving 13 international experts and three methodologists used the GRADE approach for guideline development. Methods: The task force identified four main topics: red blood cell transfusion thresholds, red blood cell transfusion avoidance strategies, platelet transfusion, and plasma transfusion. The panel developed structured guideline questions using population, intervention, comparison, and outcomes (PICO) format. Results: The task force generated 16 clinical practice recommendations (3 strong recommendations, 13 conditional recommendations), and identified five PICOs with insufficient evidence to make any recommendation. Conclusions: This clinical practice guideline provides evidence-based recommendations and identifies areas where further research is needed regarding transfusion practices and transfusion avoidance in non-bleeding, critically ill adults.

Published
2020

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