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The race to capture consumers' attention has rapidly increased in the past years. Besides the importance of the channels, the elements composing an ad are as crucial as ever in promoting compelling messages relevant to the target group. Music is one of the mechanisms through which the interest of consumers can be aroused while enhancing the advertising message and giving it more nuance. There have been several attempts to understand advertising music better, but most of the works focus on individual dimensions. There is a need to understand advertising music choices more coherently and complexly. The present study aims to provide a comprehensive instrument of several items that help understand musical congruency within an ad. The paper provides a content analysis of 95 global musical ads for 2019-2022. The primary product/service categories are reviewed, and the dimensions used in the analysis present the essential aspects of musical congruency, underlining the importance of original music composed for the ads, the capacity to adapt to various music sources, and giving additional importance to elements such as pitch, dynamics, and tempo. The paper offers a bigger picture of the musical landscape in advertising and interweaves music knowledge and elements with advertising purposes. [ABSTRACT FROM AUTHOR]

Social media is associated with the rise of new types of celebrities called influencers, who share their current experiences and ideas and often endorse brands. Developing and keeping a large community of followers is one of the most important goals of influencers. The size of their audiences is one of the elements that make them relevant to the advertising industry. The main objective of the present research is to explore the mechanism that determines users' online behavior related to influencers, such as following them on social media. Moreover, the study examined the role of the perceived information quality and of the perceived trust of the influencers in shaping audiences' attitudes toward influencers. The moderating role of the frequency of Instagram and YouTube use on the relationship between perceived information quality and trustworthiness was explored by conducting an online survey (N=1088). The main takeaway from the study is that influencers who want to grow their audiences have to create perceived quality content. This can contribute to both positive attitudes and the development of trust. Also, the frequency of Instagram use has a small moderating role, while the frequency of YouTube use has no effects on the trustworthiness of the influencers. [ABSTRACT FROM AUTHOR]

News sharing on social network sites is a common nowadays activity with complex implications. Our model combines content characteristics such as perceived information quality with the intensity of SNS use and risk propensity as predictors for news sharing on Facebook. We conducted a survey (N= 586) consists of early stage adults from Romania and Germany. In line with previous research, perceived information enjoyability and perceived information relevance are predictors for news sharing for both groups. Contrary to previous literature, perceived information reliability do not influence news sharing. Risk-taking propensity has also no influence on news sharing for none of our researched group. [ABSTRACT FROM AUTHOR]

In the present study we focus on the use of social network sites by Romanian and German youth in a comparative manner. Our research questions are 1. Are there differences in the use of social network sites by young people in Germany and Romania? 2. Are there differences in the motivation to use social network sites? and 3. How do they see the information shared on social networks? The present study is of exploratory nature and it was only the first step in analyzing the differences between Romanian and German students with respect to the use of SNS such as Facebook, Instagram, Snapchat and WhatsApp. Based on a qualitative methodology, our results cannot be subject for generalization. Nevertheless, we emphasized some relevant tendency such as: a migration towards Instagram in both Romania and Germany and similar reasons for this behavior. Privacy seemed to be much more relevant for the German students than for the Romanian and this is reflected in news sharing behavior. Differences in the diffusion of information and innovation are not that relevant taking into consideration a global digital perspective. [ABSTRACT FROM AUTHOR]

The aim of the present paper is identifying the mechanisms through which students form their interpersonal and professional universe in the academic medium, as well as the profile of the opinion leaders they follow and aspire to. For the empirical part, there were three focusgroups and 24 interviews designed, with students from all years of study. The focus groups were made with students from the College of Political, Administrative and Communication Sciences (BabeŞ-Bolyai University) and the interviews were carried with students from the College of Automatics and Computers (Technical University). There was also a pilot-experiment with the students from the College of Political, Administrative and Communication Sciences, designed to generate new data with which to associate the information obtained in the focus-groups. [ABSTRACT FROM AUTHOR]

The study is a qualitative approach on how the cultural imperialism affects the belongingness feeling of the Romanian youth. The main role in this phenomenon is attributed to the mass media. The methods used involve a pre-test, consisting of a focus group, combined with an experiment and a small survey, and further on, a series of interviews. The provided answers help at shaping a general image of how different generations, and especially the present young generation, perceive themselves in comparison to the Western values. This "inside-outside" approach of the subject allows making a sketch of the modern Romanian youth. [ABSTRACT FROM AUTHOR]

Transition to market economy has produced major changes within the Romanian industrial sector. Entire production units went bankrupt determining the arising of a new issue related to urban space: brownfields. Deindustrialization represents one of the major trends of cities' recent history. The phenomenon of industry restructuring meant in the majority of cases its disappearance accompanied by the dropout of the initial locations while conversion was carried out following the demolition of initial establishments in view of building new ones. The article analyses the violent transformation of the industrial sector from Iasi, carrying out an in-depth analysis of the Iasi industry before and after the falling of communism as well as the effects of deindustrialization on the morphology of Iasi. As the conversion of industrial regions is dependent on economic imperatives, there is at present a need for approaching the concept of sustainable development in the context of a reconstructing environment. [ABSTRACT FROM AUTHOR]

• Overview of human-wildlife interactions governance measures. • Human–wildlife conflicts could be diminished through social network approach. • Interconnected management system for HWI. Human-wildlife interactions (HWI) are present in areas where wild animals and humans compete for limited space, sometimes resulting in potentially harmful conflicts on both sides. The upper Prahova Valley within the central Carpathian range of Romania represents an area where interactions between humans and wildlife can still be found, but potentially conflicting due to the presence of both large intact natural habitats and increasing human pressure over the environment. In our study, we hypothesize that an adequate understanding of the HWI problem involves analyses on landscape pattern, natural or human induced triggering factors, and local stakeholders' perception of the phenomenon including the measures they consider suitable for optimizing their interactions with wild animals. Therefore, the goal of our paper was to analyse the characteristics of the HWI phenomenon in the upper Prahova Valley, based on exploring the local stakeholders' perspective. The study methodology consists of three steps: (i) applying 450 questionnaires to local stakeholders in order to extract HWI data; (ii) detecting the interconnection between various types of HWI and the perception of local people, using statistical and network approaches; and (iii) develop a set of recommendations which are applicable at both, local and regional decisional level in order to decrease the negative impact of HWI, enhance wildlife conservation strategies and promote a sustainable interactions with humans and mitigate potential conflicts that occur between humans and wildlife. The results indicate that the brown bear, wild boar and red fox were constantly increasing in HWI after 1990, while interactions with Eurasian wolf, stone marten, European polecat, roe deer and mountain viper were usually scarcer. The brown bear and wild boar were the prior species involved in conflict interactions with humans, such as the destruction of fences, orchards, or gardens. The bear was the only wildlife responsible for non-fatal human attacks. Locals consider the lack of wildlife food supply by the forest staff and the deficient forest management practices after 1990 to be the main triggering factors of these negative HWI. They perceive that the interactions with these animals pose a high risk to human security. Our results stand as a strong argument for a complex management system concerning the HWI phenomenon which adapts upper-level policies and governance decisions to both local stakeholder's needs and wildlife management objectives to be achieved in order to attain a favorable conservation status. [ABSTRACT FROM AUTHOR]

We aimed to investigate immunohistochemical expression of the p53 tumor suppressor protein, and the B-cell lymphoma-2 (Bcl-2) apoptotic protein in colorectal adenocarcinoma patients with or without type 2 diabetes mellitus (T2DM). Tissue sections from 95 paraffin-embedded colorectal adenocarcinomas, originating from 52 T2DM and 43 non-diabetic patients, were immunostained for p53 [Ventana mouse monoclonal primary antibody (mAb) in vitro diagnostic (IVD) anti-p53, clone Bp53-11] and Bcl-2 (Ventana mAb IVD anti-Bcl-2, clone Bcl-2/124). Immunohistochemistry analysis did not find statistically significant differences between the two groups, but analysis on subgroups of patients in terms of presence or absence of obesity identified overexpression of p53 (>70% of cells) in the T2DM obese patients compared to non-diabetics. Overexpression of p53 was present in 80% of tumor cells coming from T2DM obese patients compared to 37.2% of tumor cells coming from non-diabetics obese and non-obese, and in 36.6% of tumor cells coming from non-diabetic non-obese patients (p=0.024). There was a single non-diabetic obese patient with p53 overexpression. Most cancer cells of T2DM obese patients presented more frequently p53 overexpression by comparison with cancer cells of the T2DM non-obese patients (80% vs 40.5%, p=0.028). Bcl-2/p53 co-expression was an infrequent event in T2DM patients' group. The results of this study suggest that patients with colorectal adenocarcinoma that associate T2DM and obesity exhibit higher p53 protein expression in malignant cells. In conclusion, our research highlights that obesity is a potential key factor in the relationship between T2DM and colorectal cancer.

Background: The increased incidence of both colorectal cancer and diabetes mellitus, as well as the fact that they are important causes of high morbidity and especially mortality, place the two pathologies on the list of priorities of the health system. There are studies which have observed that diabetes mellitus is directly involved in carcinogenesis and is an independent risk factor for colorectal cancer. The diabetic patient requires a complex medical-surgical approach, so setting the risk criteria for them can be the starting point for improving the survival rate. Materials and methods: The association between colorectal cancer and diabetes mellitus as well as screening criteria were analyzed in a descriptive prospective study (442 patients) conducted in the Dr. I. Cantacuzino Clinical Hospital during 2017-2018. In the study, patients were distributed in two clusters, one with diabetes mellitus (N = 194) and one without diabetes mellitus (N = 248) in which basic clinical and laboratory evaluations were performed followed by screening colonoscopies. Results: Statistically significant (p 0.005) correlations were highlighted between 7 of the variables tested and the positive results on colonoscopy, which were subsequently combined to achieve a risk score. Conclusions: Diabetes mellitus is an independent risk factor and a negative prognostic factor for colorectal cancer. The risk score described as a result of this study is a feasible, simple solution for early detection of precursor lesions or neoplasms with the ultimate goal of improving the prognosis and survival of these patient., (Celsius.)

Peritoneal dialysis (PD) is a method of renal function replacement which has a series of advantages like greater autonomy of the patient with fewer hospital visits and better preservation of residual renal function, but it has also disadvantages. The main disadvantages are a limited life-time due to peritoneal membrane failure and the risk of infections. The main complication of PD remains peritonitis, which is responsible for the most cases of method failure. There are also other complications which incorrect treated may lead to failure of the method: mechanical complications, abdominal wall defects, exit site and tunnel infections. Encapsulating peritoneal sclerosis is a rare entity found in PD patients but with high morbidity and mortality. We have retrospectively analyzed the patients with end stage renal disease under peritoneal dialysis which were admitted to Surgical Clinic "I. Juvara" of the Clinical Hospital "Dr. I. Cantacuzino" between 2007 and 2017 for surgical complications related to PD. The patients were assigned in two groups: with non-infectious and infectious complications. We have found 109 patients which have had 126 surgical interventions related to peritoneal dialysis. Out of these, 30 interventions consisted in catheter removal for loss of ultrafiltration capacity, so these were excluded from analysis. The lot resulted consisted in 80 patients with 91 complications: 42 non-infectious and 49 infectious. Mean age was 60.5 (+-12.3) years. Sex distribution was 2.75/1 male/female. Diabetes mellitus was present at 45 (56,25 %) patients. Comparing the patients with non-infectious with those with infectious complications we found significant association between type of complications and the length of PD in the sense that infectious complications tend to appear later than the non-infectious. Also, the loss of peritoneal dialysis is strongly associated with infectious complications. Looking inside groups we found that abdominal wall defects are associated with the history of previous abdominal surgery (p 0,001). Regarding the morbidity and mortality only infectious complications had associated mortality in our study, there were no significant differences in morbidity rate between groups. Between all these patients we have also identified 16 with encapsultating peritoneal sclerosis. In most cases the diagnosis was established during the intervention for another complication. We have registered a 20% morality rate at these patients. Conclusions: Noninfectious surgical complications are not raising problems for diagnosis or surgical treatment, but an incorrect treatment may lead to failure of the PD. Infectious complications and especially peritonitis remains the main cause of method failure. These are generating the highest rates of morbidity and mortality from peritoneal dialysis complications. Even if the immediate surgical intervention for peritonitis related to peritoneal dialysis is usually unnecessary, surgical observation is absolutely mandatory in every case. The absence of a response to the proper medical treatment is an indication for peritoneal cavity exploration inclusive by laparoscopy/laparotomy. Any delay in diagnosis and definitive treatment can lead to loss of peritoneal membrane function and even death of the patient. Encapsulated peritoneal sclerosis is a rare but serious complication of PD. The risk for developing EPS increases with the duration of PD treatment. No predictive and reliable screening tests especially in the early stages of EPS were found. So, it is important not to underestimate the clinical symptoms, diagnosis being based on a high index of suspicion. The only established basic treatment of EPS is enterolysis of peritoneal adhesions, and time should not be unnecessarily wasted on conservative treatment., (Celsius.)

Background: Diabetic foot complications result from the association between peripheral vascular disease, neuropathy and a precarious healing process. Peripheral neuropathy observed in diabetics affects all components of the nervous system, contributing to the occurrence of leg ulcers, musculoskeletal changes, resulting in severe deformities. The clinical manifestation of these complications ranges from simple lesions to complex entities threatening the loss of pelvic limb or even life (1,2). Methods: In our surgery department, a significant number of patients with diabetic foot lesions are hospitalized and treated annually, 40% having clinical manifestations of diabetic neuropathy associated. In 2017, a total of 448 patients were hospitalized for complications of diabetes. We performed a retrospective analysis of 150 consecutive patients who underwent surgery for neuropathic diabetic foot lesions. Results: The analyzed patients had a favorable postoperative progression, benefiting from distal perfusion. Ray resection was the preferred surgical intervention. Major amputation was performed in 10% of cases with extensive gangrene and sepsis, amputation of the calf being preferred in all situations. Conclusions: The management of these patients is delicate, often multidisciplinary approach being necessary. A well-managed therapeutic attitude can make the difference between preserving or losing the pelvic limb., (Celsius.)

Background: the patient with diabetes has an increased susceptibility to infections, with negative evolutionary potential leading to increased morbidity and mortality compared to the general population. The cause is the alteration of immune defense mechanisms, the hyperglycemic environment leading to alteration of neutrophil function, suppression of the antioxidant system and humoral activity, systemic micro and macroangiopathy, neuropathy, depression of antibacterial activity of the genitourinary and digestive tract. Infections localized at the soft tissue (skin, fascia and aponeurosis, subcutaneous tissue, muscles) in the diabetic patient require a complex medico-surgical approach in which aggressive surgical treatment should be complemented by metabolic balancing and sustained antibiotic therapy. Materials and methods: these peculiarities will be exposed and analyzed in a retrospective descriptive study performed at the General Surgery Clinic. Juvara of the clinical hospital Dr. I. Cantacuzino, during the period of Jan. 2013- Dec.2017, which followed the type of lesions, their localization, the germs involved, the comorbidities, the biologic parameters, the antibiotic and surgical treatment as well as the postoperative evolution. The study does not include patients with localized infections in the diabetic foot, a particular pathological entity that will be analyzed separately in a separate study. Results: 150 diabetic patients with soft tissue infections localized in the upper limb, calf, thigh, perineum, abdominal and thoracic wall were identified. The most frequent localization was found in the lower limb (54%). The incidence of these infections was higher in males (55%), and the most affected age group was 60-69 years (38%). Most patients had type II diabetes (93%). Among the associated comorbidities, cardiovascular diseases and obesity are the most common, explaining to a large extent the complicated evolution, potentially lethal of this pathology. From the bacteriological perspective, a plurimicrobian flora is identified, staphylococcus aureus being most frequently encountered. The antibiotic treatment was initiated immediately empirically, subsequently according to the antibiogram; the most commonly used antibiotic classes being cephalosporins and carbapenems. Surgical interventions were in their majority of debridement and necrectomy, but in a few cases limb amputation was necessary. In particular, the number of surgical interventions performed in the same patient and in the same hospital stay was between 1 and 7 interventions. Conclusions: Soft tissue infections in the diabetic patient have a heterogeneous aspect with specific particularities requiring careful clinical examination, multidisciplinary treatment including rapid, serial surgical interventions to control the growing aggression of the germs involved. Fast and caseadapted therapeutic decisions, careful observation of the patient's general condition and of the wound several times a day are essential to achieving favorable postoperative outcomes., (Celsius.)

Colorectal cancer and Diabetes Mellitus represent a major public health issue, first, by the number of new cases which are at an alarming rate. Secondly, by the negative effect over the quality of life, socio-economic status and lifespan, representing high morbidity and mortality causes. Diabetes Mellitus is the disease of the century with a global prevalence (standardised-age) which doubled since 1980, rising from 4,7% to 8,5% in adult population. In 2012, the estimated number of fatalities caused by Diabetes Mellitus and other related complications was at 3,7 million, out of which 43% were patients under the age of 70. Neoplasia represents the second cause of death, after cardiovascular disease. The occurrence of Colorectal cancer (CRCA) is rated for men and women at 3rd and 2nd place. However, the rate of mortality from CRCA is in the 4th place, representing 8,5% out of the total cancer related deaths. 52% of these cases are recorded in underdeveloped countries, considering their level, this reflects a very low survival rate. Moreover, every year, approximately 1.4 million cases are being diagnosed out of which 55% appear in overdeveloped countries. Screening for colorectal cancer refers to the periodical evaluation of the asymptomatic patients who are at a risk of developing this type of neoplasia. The colorectal cancer contains a series of particularities which makes it ideal for screening. Since the end of the 19th century there has been a high suspicion that type II diabetes, through direct etiological mechanisms, may play a part in carcinogenesis (breast, endometrium, colorectal, pancreas, liver, non-Hodgkin's lymphoma). At the moment, the relevant published literature presents type II diabetes as an independent risk factor for colorectal cancer. Although, despite experimental proof, many epidemiological studies, case-controlled studies and meta-analysis, there still is the necessity for prospective studies which can intensify the existing results and can allow the colorectal cancer screening to adapt to these patients., (Celsius.)