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3. Co-circulation of monkeypox virus subclades Ia and Ib in Kinshasa Province, Democratic Republic of the Congo, July to August 2024.

Author

Wawina-Bokalanga T, Akil-Bandali P, Kinganda-Lusamaki E, Lokilo E, Jansen D, Amuri-Aziza A, Makangara-Cigolo JC, Pukuta-Simbu E, Ola-Mpumbe R, Muyembe M, Kacita C, Paku-Tshambu P, Dantas PH, Tshiani-Mbaya O, Luakanda G, Nkuba-Ndaye A, Matondo M, Vakaniaki EH, Tessema S, Ndembi N, O'Toole Á, De Block T, Ngandu C, Hoff NA, Low N, Subissi L, Merritt S, Muyembe-Tamfum JJ, Liesenborghs L, Peeters M, Delaporte E, Kindrachuk J, Rimoin AW, Ahuka-Mundeke S, Rambaut A, Mwamba D, Vercauteren K, and Mbala-Kingebeni P

Subjects
Democratic Republic of the Congo epidemiology, Humans, Genome, Viral, RNA, Viral genetics, Male, Sequence Analysis, DNA, Mpox, Monkeypox epidemiology, Mpox, Monkeypox virology, Monkeypox virus genetics, Monkeypox virus isolation & purification, Phylogeny, Disease Outbreaks
Abstract

Between January and August 2024, mpox cases have been reported in nearly all provinces of the Democratic Republic of the Congo (DRC). Monkeypox virus genome sequences were obtained from 11 mpox cases' samples, collected in July-August 2024 in several health zones of Kinshasa. Characterisation of the sequences showed subclades Ia and Ib co-circulating in the Limete health zone, while phylogenetic analyses suggested multiple introductions of the two subclades in Kinshasa. This illustrates the growing complexity of Clade I mpox outbreaks in DRC.

Published
2024
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