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Your search keyword '"Mycobacteria -- Prevention"' showing total 4 results
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4 results on '"Mycobacteria -- Prevention"'

1. Mycobacterium ulcerans disease

Author

van der Weff, Tjip S., Stienstra, Ymkje, Johnson, R. Christian, Dick, Philip K., Adjei, Ohene, Fleischer, Bernhard, Wansbrough-Jones, Mark H., Johnson, Paul D.R., Portaels, Francoise, van der Graaf, Winette T.A., and Asiedu, Kingsley

Subjects
Mycobacteria -- Development and progression, Mycobacteria -- Prevention, Mycobacteria -- Research, Mycobacterium -- Development and progression, Mycobacterium -- Prevention, Mycobacterium -- Research
Abstract

Mycobacterium ulcerans disease (Buruli ulcer) is an important health problem in several west African countries. It is prevalent in scattered foci around the world, predominantly in riverine areas with a humid, hot climate. We review the epidemiology, bacteriology, transmission, immunology, pathology, diagnosis and treatment of infections. M. ulcerans is an ubiquitous micro-organism and is harboured by fish, snails, and water insects. The mode of transmission is unknown. Lesions are most common on exposed parts of the body, particularly on the limbs. Spontaneous healing may occur. Many patients in endemic areas present late with advanced, severe lesions. BCG vaccination yields a limited, relatively short-lived, immune protection. Recommended treatment consists of surgical debridement, followed by skin grafting if necessary. Many patients have functional limitations after healing. Better understanding of disease transmission and pathogenesis is needed for improved control and prevention of Buruli ulcer. Keywords Mycobacterium ulcerans/pathogenicity; Mycobacterium infections, Atypical/etiologylepidemiology/therapy; Review literature; Meta-analysis; Africa, Western (source: MeSH, NLM). Mots cles Mycobactefium ulceranslpathogenicite; Mycobacterium atypique, Infectionletiologielepidemiologieltherapeutique; Revue de la litterature; Meta-analyse; Afrique de l'Ouest (source: MeSH, INSERM). Palabras clave Mycobacterium ulcerans/patogenicidad; Micobacteriosis atipica/etiologia/epidemiologia/terapia; Literatura de revision; Metaanalisis; Africa Ocidental (fuente: DeCS, BIREME). [TEXT NOT REPRODUCIBLE IN ASCII.], Resume Infection a Mycobacterium ulcerans L'infection a Mycobacterium ulcerans (ulcere de Buruli) constitue un important probleme sanitaire dans plusieurs pays d'Afrique de l'Ouest. Elle est prevalente sous forme de foyers [...]

Published
2005

2. Cytotoxicity and antitubercular activity of allium sativum and lantana camara against mycobacterial isolates from people living with HIV/AIDS

Author

Dibua, U.E., Odo, G.E., Udengwu, S., and Esimone, C.O.

Subjects
Garlic -- Health aspects, HIV patients -- Care and treatment, Drug resistance in microorganisms -- Evaluation, Mycobacteria -- Prevention, Mycobacterium -- Prevention, Health
Abstract

The Antitubercular activity of Allium sativum and Lantana camara on multiple-drug-resistant Mycobacterium was investigated among Nigerian HIV-infected-persons. Minimal inhibitory concentration (MIC) was estimated by the well-in-agar-diffusion method and potency of extracts compared with standard drugs. Cytotoxicity was determined using brine shrimps. MIC of drugs was 0.33mg/ml, 0.25mg/ml and 0.20mg/ml for streptomycin, isoniazide and rifampicin. L. camara had MIC of 0.63mg/ml for M. tuberculosis and Unidentified M. avium complex and 0.89mg/ml for M. avium Complex while garlic had 0.64mg/ml for M. tuberculosis, 0.97mg/ml for M. avium Complex and 1mg/ml for Unidentified species. [LC.sub.50] of garlic was 49.1 ppm for M. tuberculosis, 56.5ppm for M. avium complex and 63.0ppm for the Unidentified species, while L. camara had 32.6ppm for M. tuberculosis, 55.9ppm for M. avium complex and 51.3ppm for Unidentified species. The observed activity of the extracts is consistent with their use in traditional medicine for the treatment of Mycobacterium species. Keywords: Antitubercular | cytotoxicity | Minimal inhibitory concentration (MIC) | HIV-infected-persons, Introduction Tuberculosis (TB), by members of the Mycobacterium tuberculosis complex, causes three million deaths a year worldwide (1). The disease is associated with impoverished economic conditions. The resurgence of M. [...]

Published
2010

3. Mycobacterium ulcerans infection (Buruli or Bairnsdale ulcer): Challenges in developing management strategies

Author

Asiedu, Kingsley and Wansbrough-Jones, Mark

Subjects
Mycobacteria -- Diagnosis, Mycobacteria -- Risk factors, Mycobacteria -- Prevention, Mycobacterium -- Diagnosis, Mycobacterium -- Risk factors, Mycobacterium -- Prevention, Polymerase chain reaction -- Observations, Health
Abstract

Various findings obtained from several observational studies are used to observe the combination of Buruli or Bairnsdale ulcer (BU), caused by the microorganism Mycobacterium ulcerans, with surgery, antibiotics or both. The polymerase chain reaction (PCR) testing of the excised tissue has played a very important role in the diagnosis of the disease, though the development of easier management strategies still remains a challenge.

Published
2007

4. Swimming with the fishes

Subjects
Mycobacteria -- Health aspects, Mycobacteria -- Prevention, Mycobacterium -- Health aspects, Mycobacterium -- Prevention
Published
2004

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