1,965 results on '"Myers, Andrew"'
Search Results
2. Application of mesh refinement to relativistic magnetic reconnection
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Jambunathan, Revathi, Jones, Henry, Corrales, Lizzette, Klion, Hannah, Rowan, Michael, Myers, Andrew, Zhang, Weiqun, and Vay, Jean-Luc
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Physics - Computational Physics ,Astrophysics - High Energy Astrophysical Phenomena ,Physics - Plasma Physics - Abstract
During relativistic magnetic reconnection, antiparallel magnetic fields undergo a rapid change in topology, releasing a large amount of energy in the form of non-thermal particle acceleration. This work explores the application of mesh refinement to 2D reconnection simulations to efficiently model the ineherent disparity in length-scales. We have systematically investigated the effects of mesh refinement and determined necessary modifications to the algorithm required to mitigate non-physical artifacts at the coarse-fine interface. We have used the ultrahigh-order Pseudo-Spectral Analytical Time-Domain (PSATD) Maxwell solver to analyze how its use can mitigate the numerical dispersion that occurs with the finite-difference time-domain (FDTD) (or ``Yee'') method. Absorbing layers are introduced at the coarse-fine interface to eliminate spurious effects that occur with mesh refinement. We also study how damping the electromagnetic fields and current density in the absorbing layer can help prevent the non-physical accumulation of charge and current density at the coarse-fine interface. Using a mesh refinement ratio of 8 for two-dimensional magnetic reconnection simulations, we obtained good agreement with the high resolution baseline simulation, using only 36% of the macroparticles and 71% of the node-hours needed for the baseline. The methods presented here are especially applicable to 3D systems where higher memory savings are expected than in 2D, enabling comprehensive, computationally efficient 3D reconnection studies in the future.
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- 2024
3. SCIF: A Language for Compositional Smart Contract Security
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Yao, Siqiu, Ni, Haobin, Myers, Andrew C., and Cecchetti, Ethan
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Computer Science - Cryptography and Security ,Computer Science - Programming Languages - Abstract
Securing smart contracts remains a fundamental challenge. At its core, it is about building software that is secure in composition with untrusted code, a challenge that extends far beyond blockchains. We introduce SCIF, a language for building smart contracts that are compositionally secure. SCIF is based on the fundamentally compositional principle of secure information flow, but extends this core mechanism to include protection against reentrancy attacks, confused deputy attacks, and improper error handling, even in the presence of malicious contracts that do not follow SCIF's rules. SCIF supports a rich ecosystem of interacting principals with partial trust through its mechanisms for dynamic trust management. SCIF has been implemented as a compiler to Solidity. We describe the SCIF language, including its static checking rules and runtime. Finally, we implement several applications with intricate security reasoning, showing how SCIF supports building complex smart contracts securely and gives programmer accurate diagnostics about potential security bugs.
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- 2024
4. Seeking What Is Right: The Old Testament and the Good Life by Iain Provan (review)
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Myers, Andrew
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- 2022
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5. Synthesizing Particle-In-Cell Simulations through Learning and GPU Computing for Hybrid Particle Accelerator Beamlines
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Sandberg, Ryan, Lehe, Remi, Mitchell, Chad, Garten, Marco, Myers, Andrew, Qiang, Ji, Vay, Jean-Luc, and Huebl, Axel
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Information and Computing Sciences ,Applied Computing ,Physical Sciences ,Bioengineering ,Machine Learning and Artificial Intelligence ,Generic health relevance ,ATAP-GENERAL ,ATAP-2024 ,ATAP-BELLA Center ,ATAP-AMP - Published
- 2024
6. AMReX and pyAMReX: Looking Beyond ECP
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Myers, Andrew, Zhang, Weiqun, Almgren, Ann, Antoun, Thierry, Bell, John, Huebl, Axel, and Sinn, Alexander
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Computer Science - Distributed, Parallel, and Cluster Computing - Abstract
AMReX is a software framework for the development of block-structured mesh applications with adaptive mesh refinement (AMR). AMReX was initially developed and supported by the AMReX Co-Design Center as part of the U.S. DOE Exascale Computing Project, and is continuing to grow post-ECP. In addition to adding new functionality and performance improvements to the core AMReX framework, we have also developed a Python binding, pyAMReX, that provides a bridge between AMReX-based application codes and the data science ecosystem. pyAMReX provides zero-copy application GPU data access for AI/ML, in situ analysis and application coupling, and enables rapid, massively parallel prototyping. In this paper we review the overall functionality of AMReX and pyAMReX, focusing on new developments, new functionality, and optimizations of key operations. We also summarize capabilities of ECP projects that used AMReX and provide an overview of new, non-ECP applications., Comment: 12 pages, 1 figure, submitted to the International Journal of High Performance Computing Applications
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- 2024
7. Synthesizing Particle-in-Cell Simulations Through Learning and GPU Computing for Hybrid Particle Accelerator Beamlines
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Sandberg, Ryan T., Lehe, Remi, Mitchell, Chad E., Garten, Marco, Myers, Andrew, Qiang, Ji, Vay, Jean-Luc, and Huebl, Axel
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Physics - Accelerator Physics ,Physics - Computational Physics - Abstract
Particle accelerator modeling is an important field of research and development, essential to investigating, designing and operating some of the most complex scientific devices ever built. Kinetic simulations of relativistic, charged particle beams and advanced plasma accelerator elements are often performed with high-fidelity particle-in-cell simulations, some of which fill the largest GPU supercomputers. Start-to-end modeling of a particle accelerator includes many elements and it is desirable to integrate and model advanced accelerator elements fast, in effective models. Traditionally, analytical and reduced-physics models fill this role. The vast data from high-fidelity simulations and power of GPU-accelerated computation open a new opportunity to complement traditional modeling without approximations: surrogate modeling through machine learning. In this paper, we implement, present and benchmark such a data-driven workflow, synthesising a fully GPU-accelerated, conventional-surrogate simulation for hybrid particle accelerator beamlines., Comment: 11 pages, 10 figures. Accepted to PASC24 proceedings
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- 2024
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8. Secure Synthesis of Distributed Cryptographic Applications (Technical Report)
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Acay, Coşku, Gancher, Joshua, Recto, Rolph, and Myers, Andrew C.
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Computer Science - Cryptography and Security ,Computer Science - Programming Languages - Abstract
Developing secure distributed systems is difficult, and even harder when advanced cryptography must be used to achieve security goals. Following prior work, we advocate using secure program partitioning to synthesize cryptographic applications: instead of implementing a system of communicating processes, the programmer implements a centralized, sequential program, which is automatically compiled into a secure distributed version that uses cryptography. While this approach is promising, formal results for the security of such compilers are limited in scope. In particular, no security proof yet simultaneously addresses subtleties essential for robust, efficient applications: multiple cryptographic mechanisms, malicious corruption, and asynchronous communication. In this work, we develop a compiler security proof that handles these subtleties. Our proof relies on a novel unification of simulation-based security, information-flow control, choreographic programming, and sequentialization techniques for concurrent programs. While our proof targets hybrid protocols, which abstract cryptographic mechanisms as idealized functionalities, our approach offers a clear path toward leveraging Universal Composability to obtain end-to-end, modular security results with fully instantiated cryptographic mechanisms. Finally, following prior observations about simulation-based security, we prove that our result guarantees robust hyperproperty preservation, an important criterion for compiler correctness that preserves all source-level security properties in target programs.
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- 2024
9. A Compiler from Array Programs to Vectorized Homomorphic Encryption
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Recto, Rolph and Myers, Andrew C.
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Computer Science - Programming Languages ,Computer Science - Cryptography and Security - Abstract
Homomorphic encryption (HE) is a practical approach to secure computation over encrypted data. However, writing programs with efficient HE implementations remains the purview of experts. A difficult barrier for programmability is that efficiency requires operations to be vectorized in inobvious ways, forcing efficient HE programs to manipulate ciphertexts with complex data layouts and to interleave computations with data movement primitives. We present Viaduct-HE, a compiler generates efficient vectorized HE programs. Viaduct-HE can generate both the operations and complex data layouts required for efficient HE programs. The source language of Viaduct-HE is array-oriented, enabling the compiler to have a simple representation of possible vectorization schedules. With such a representation, the compiler searches the space of possible vectorization schedules and finds those with efficient data layouts. After finding a vectorization schedule, Viaduct-HE further optimizes HE programs through term rewriting. The compiler has extension points to customize the exploration of vectorization schedules, to customize the cost model for HE programs, and to add back ends for new HE libraries. Our evaluation of the prototype Viaduct-HE compiler shows that it produces efficient vectorized HE programs with sophisticated data layouts and optimizations comparable to those designed by experts.
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- 2023
10. Emerging Trends in Customer Management in a Changing World
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Dibley, Anne, Clark, Moira, and Myers, Andrew
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customer management ,organizational culture ,customer innovation ,customer engagement ,Marketing. Distribution of products ,HF5410-5417.5 ,Economics as a science ,HB71-74 - Abstract
The number of customer management related research publications has increased significantly over the last decade (a 70 per cent increase); where key areas or themes have mainly focused upon subjects such as customer satisfaction, customer service, customer loyalty, customer relationship management and customer value. The number of published articles relating to customer relationship management appears to be on the decline, having peaked in 2013 (a 25 per cent decrease); whilst other key themes have remained fairly steady. This would suggest that new trends in customer management are emerging, or are on the increase. The objective of this paper is to explore and highlight current and future trends in customer management by means of a literature review of marketing and related journals/texts spanning the last twelve months. The outcomes of this review and their relevance to marketing and customer management include themes relating to getting the organizational culture right, as well as adapting and connecting better with customers. Furthermore themes relating to personalization and designing customer journeys, as well as understanding the influence of innovation, co-creation and social media, can all influence brand credibility among customers. The themes highlighted all relate to ways in which companies can enhance their engagement and interaction with customers in a changing world; a world that is changing because of advances in technology and a proliferation of online communication, alongside increasingly powerful and demanding customers. Today’s customers prefer to buy from companies who, not only genuinely understand their needs, but also understand how their offerings fit into their customers’ lives. This paper summarizes trends that are relevant to both academia and business, where customers’ expectations of companies are higher than ever before. Looking beyond customer relationship management can help companies better understand these new trends and innovations and how they can prepare better for the future.
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- 2016
11. Promoting Excellence in Customer Management: Emerging Trends in Business
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Clark, Moira, Harrington, Tony, and Myers, Andrew
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trend analysis ,engaged culture ,customer journey ,customer innovations ,customer-centric focus ,Marketing. Distribution of products ,HF5410-5417.5 ,Economics as a science ,HB71-74 - Abstract
The importance of customer management as an area for research inspired the formation of an academic, UK based customer management research centre in 2006. The Centre is a unique collaboration between business and academia, which aims to promote excellence in customer management. Together its members discuss and share current challenges to create a genuine opportunity that harnesses the forward thinking that delivers growth; building transferable knowledge and turning it into effective practice. The purpose of this paper is to share the findings of a ten year longitudinal study of customer management issues that have been identified by businesses that have collaborated with the research centre; and to identify emerging trends in marketing that are being reported and which will provide opportunities for future research through practical best practice case study examples. Over the last decade many themes have emerged and have been researched within the Centre; areas such as gaining insight into on-line and off-line customer experiences, managing out-sourced relationships, multi-channel marketing and dealing with service recovery through effective complaint handling. Using social media for innovation, collaboration and commercialization has also been a key theme that has frequently been raised. One area that members have identified as an emerging focus for research is managing the customer journey more effectively so that organizations can make it easier to become a customer whilst simultaneously adding value to the customer experience. A further research opportunity is exploring how organizations can effectively develop the softer side of their business to improve customer management, for example, how to achieve an engaged culture and climate so that it improves business performance. By identifying these emerging business trends it is then possible to design a research agenda that will help companies to continuously innovate and adapt; leading to an improved customer-centric focus and sustaining a competitive edge.
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- 2016
12. Structural basis of Cfr-mediated antimicrobial resistance and mechanisms to evade it
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Aleksandrova, Elena V., Wu, Kelvin J. Y., Tresco, Ben I. C., Syroegin, Egor A., Killeavy, Erin E., Balasanyants, Samson M., Svetlov, Maxim S., Gregory, Steven T., Atkinson, Gemma C., Myers, Andrew G., and Polikanov, Yury S.
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- 2024
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13. Patterns of Comorbidities and Prescribing and Dispensing of Non-steroidal Anti-inflammatory Drugs (NSAIDs) Among Patients with Osteoarthritis in the USA: Real-World Study
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Ide, Joshua, Shoaibi, Azza, Wagner, Kerstin, Weinstein, Rachel, Boyle, Kathleen E., and Myers, Andrew
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- 2024
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14. Particle-in-Cell Simulations of Relativistic Magnetic Reconnection with Advanced Maxwell Solver Algorithms
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Klion, Hannah, Jambunathan, Revathi, Rowan, Michael E., Yang, Eloise, Willcox, Donald, Vay, Jean-Luc, Lehe, Remi, Myers, Andrew, Huebl, Axel, and Zhang, Weiqun
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Astrophysics - High Energy Astrophysical Phenomena ,Computer Science - Computational Engineering, Finance, and Science - Abstract
Relativistic magnetic reconnection is a non-ideal plasma process that is a source of non-thermal particle acceleration in many high-energy astrophysical systems. Particle-in-cell (PIC) methods are commonly used for simulating reconnection from first principles. While much progress has been made in understanding the physics of reconnection, especially in 2D, the adoption of advanced algorithms and numerical techniques for efficiently modeling such systems has been limited. With the GPU-accelerated PIC code WarpX, we explore the accuracy and potential performance benefits of two advanced Maxwell solver algorithms: a non-standard finite difference scheme (CKC) and an ultrahigh-order pseudo-spectral method (PSATD). We find that for the relativistic reconnection problem, CKC and PSATD qualitatively and quantitatively match the standard Yee-grid finite-difference method. CKC and PSATD both admit a time step that is 40% longer than Yee, resulting in a ~40% faster time to solution for CKC, but no performance benefit for PSATD when using a current deposition scheme that satisfies Gauss's law. Relaxing this constraint maintains accuracy and yields a 30% speedup. Unlike Yee and CKC, PSATD is numerically stable at any time step, allowing for a larger time step than with the finite-difference methods. We found that increasing the time step 2.4-3 times over the standard Yee step still yields accurate results, but only translates to modest performance improvements over CKC due to the current deposition scheme used with PSATD. Further optimization of this scheme will likely improve the effective performance of PSATD., Comment: 19 pages, 10 figures. Submitted to ApJ
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- 2023
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15. The James Webb Space Telescope Mission
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Gardner, Jonathan P., Mather, John C., Abbott, Randy, Abell, James S., Abernathy, Mark, Abney, Faith E., Abraham, John G., Abraham, Roberto, Abul-Huda, Yasin M., Acton, Scott, Adams, Cynthia K., Adams, Evan, Adler, David S., Adriaensen, Maarten, Aguilar, Jonathan Albert, Ahmed, Mansoor, Ahmed, Nasif S., Ahmed, Tanjira, Albat, Rüdeger, Albert, Loïc, Alberts, Stacey, Aldridge, David, Allen, Mary Marsha, Allen, Shaune S., Altenburg, Martin, Altunc, Serhat, Alvarez, Jose Lorenzo, Álvarez-Márquez, Javier, de Oliveira, Catarina Alves, Ambrose, Leslie L., Anandakrishnan, Satya M., Andersen, Gregory C., Anderson, Harry James, Anderson, Jay, Anderson, Kristen, Anderson, Sara M., Aprea, Julio, Archer, Benita J., Arenberg, Jonathan W., Argyriou, Ioannis, Arribas, Santiago, Artigau, Étienne, Arvai, Amanda Rose, Atcheson, Paul, Atkinson, Charles B., Averbukh, Jesse, Aymergen, Cagatay, Bacinski, John J., Baggett, Wayne E., Bagnasco, Giorgio, Baker, Lynn L., Balzano, Vicki Ann, Banks, Kimberly A., Baran, David A., Barker, Elizabeth A., Barrett, Larry K., Barringer, Bruce O., Barto, Allison, Bast, William, Baudoz, Pierre, Baum, Stefi, Beatty, Thomas G., Beaulieu, Mathilde, Bechtold, Kathryn, Beck, Tracy, Beddard, Megan M., Beichman, Charles, Bellagama, Larry, Bely, Pierre, Berger, Timothy W., Bergeron, Louis E., Darveau-Bernier, Antoine, Bertch, Maria D., Beskow, Charlotte, Betz, Laura E., Biagetti, Carl P., Birkmann, Stephan, Bjorklund, Kurt F., Blackwood, James D., Blazek, Ronald Paul, Blossfeld, Stephen, Bluth, Marcel, Boccaletti, Anthony, Boegner Jr., Martin E., Bohlin, Ralph C., Boia, John Joseph, Böker, Torsten, Bonaventura, N., Bond, Nicholas A., Bosley, Kari Ann, Boucarut, Rene A., Bouchet, Patrice, Bouwman, Jeroen, Bower, Gary, Bowers, Ariel S., Bowers, Charles W., Boyce, Leslye A., Boyer, Christine T., Boyer, Martha L., Boyer, Michael, Boyer, Robert, Bradley, Larry D., Brady, Gregory R., Brandl, Bernhard R., Brannen, Judith L., Breda, David, Bremmer, Harold G., Brennan, David, Bresnahan, Pamela A., Bright, Stacey N., Broiles, Brian J., Bromenschenkel, Asa, Brooks, Brian H., Brooks, Keira J., Brown, Bob, Brown, Bruce, Brown, Thomas M., Bruce, Barry W., Bryson, Jonathan G., Bujanda, Edwin D., Bullock, Blake M., Bunker, A. J., Bureo, Rafael, Burt, Irving J., Bush, James Aaron, Bushouse, Howard A., Bussman, Marie C., Cabaud, Olivier, Cale, Steven, Calhoon, Charles D., Calvani, Humberto, Canipe, Alicia M., Caputo, Francis M., Cara, Mihai, Carey, Larkin, Case, Michael Eli, Cesari, Thaddeus, Cetorelli, Lee D., Chance, Don R., Chandler, Lynn, Chaney, Dave, Chapman, George N., Charlot, S., Chayer, Pierre, Cheezum, Jeffrey I., Chen, Bin, Chen, Christine H., Cherinka, Brian, Chichester, Sarah C., Chilton, Zachary S., Chittiraibalan, Dharini, Clampin, Mark, Clark, Charles R., Clark, Kerry W., Clark, Stephanie M., Claybrooks, Edward E., Cleveland, Keith A., Cohen, Andrew L., Cohen, Lester M., Colón, Knicole D., Coleman, Benee L., Colina, Luis, Comber, Brian J., Comeau, Thomas M., Comer, Thomas, Reis, Alain Conde, Connolly, Dennis C., Conroy, Kyle E., Contos, Adam R., Contreras, James, Cook, Neil J., Cooper, James L., Cooper, Rachel Aviva, Correia, Michael F., Correnti, Matteo, Cossou, Christophe, Costanza, Brian F., Coulais, Alain, Cox, Colin R., Coyle, Ray T., Cracraft, Misty M., Noriega-Crespo, Alberto, Crew, Keith A., Curtis, Gary J., Cusveller, Bianca, Maciel, Cleyciane Da Costa, Dailey, Christopher T., Daugeron, Frédéric, Davidson, Greg S., Davies, James E., Davis, Katherine Anne, Davis, Michael S., Day, Ratna, de Chambure, Daniel, de Jong, Pauline, De Marchi, Guido, Dean, Bruce H., Decker, John E., Delisa, Amy S., Dell, Lawrence C., Dellagatta, Gail, Dembinska, Franciszka, Demosthenes, Sandor, Dencheva, Nadezhda M., Deneu, Philippe, DePriest, William W., Deschenes, Jeremy, Dethienne, Nathalie, Detre, Örs Hunor, Diaz, Rosa Izela, Dicken, Daniel, DiFelice, Audrey S., Dillman, Matthew, Disharoon, Maureen O., van Dishoeck, Ewine F., Dixon, William V., Doggett, Jesse B., Dominguez, Keisha L., Donaldson, Thomas S., Doria-Warner, Cristina M., Santos, Tony Dos, Doty, Heather, Douglas Jr., Robert E., Doyon, René, Dressler, Alan, Driggers, Jennifer, Driggers, Phillip A., Dunn, Jamie L., DuPrie, Kimberly C., Dupuis, Jean, Durning, John, Dutta, Sanghamitra B., Earl, Nicholas M., Eccleston, Paul, Ecobichon, Pascal, Egami, Eiichi, Ehrenwinkler, Ralf, Eisenhamer, Jonathan D., Eisenhower, Michael, Eisenstein, Daniel J., Hamel, Zaky El, Elie, Michelle L., Elliott, James, Elliott, Kyle Wesley, Engesser, Michael, Espinoza, Néstor, Etienne, Odessa, Etxaluze, Mireya, Evans, Leah, Fabreguettes, Luce, Falcolini, Massimo, Falini, Patrick R., Fatig, Curtis, Feeney, Matthew, Feinberg, Lee D., Fels, Raymond, Ferdous, Nazma, Ferguson, Henry C., Ferrarese, Laura, Ferreira, Marie-Héléne, Ferruit, Pierre, Ferry, Malcolm, Filippazzo, Joseph Charles, Firre, Daniel, Fix, Mees, Flagey, Nicolas, Flanagan, Kathryn A., Fleming, Scott W., Florian, Michael, Flynn, James R., Foiadelli, Luca, Fontaine, Mark R., Fontanella, Erin Marie, Forshay, Peter Randolph, Fortner, Elizabeth A., Fox, Ori D., Framarini, Alexandro P., Francisco, John I., Franck, Randy, Franx, Marijn, Franz, David E., Friedman, Scott D., Friend, Katheryn E., Frost, James R., Fu, Henry, Fullerton, Alexander W., Gaillard, Lionel, Galkin, Sergey, Gallagher, Ben, Galyer, Anthony D., Marín, Macarena García, Gardner, Lisa E., Garland, Dennis, Garrett, Bruce Albert, Gasman, Danny, Gáspár, András, Gastaud, René, Gaudreau, Daniel, Gauthier, Peter Timothy, Geers, Vincent, Geithner, Paul H., Gennaro, Mario, Gerber, John, Gereau, John C., Giampaoli, Robert, Giardino, Giovanna, Gibbons, Paul C., Gilbert, Karolina, Gilman, Larry, Girard, Julien H., Giuliano, Mark E., Gkountis, Konstantinos, Glasse, Alistair, Glassmire, Kirk Zachary, Glauser, Adrian Michael, Glazer, Stuart D., Goldberg, Joshua, Golimowski, David A., Gonzaga, Shireen P., Gordon, Karl D., Gordon, Shawn J., Goudfrooij, Paul, Gough, Michael J., Graham, Adrian J., Grau, Christopher M., Green, Joel David, Greene, Gretchen R., Greene, Thomas P., Greenfield, Perry E., Greenhouse, Matthew A., Greve, Thomas R., Greville, Edgar M., Grimaldi, Stefano, Groe, Frank E., Groebner, Andrew, Grumm, David M., Grundy, Timothy, Güdel, Manuel, Guillard, Pierre, Guldalian, John, Gunn, Christopher A., Gurule, Anthony, Gutman, Irvin Meyer, Guy, Paul D., Guyot, Benjamin, Hack, Warren J., Haderlein, Peter, Hagan, James B., Hagedorn, Andria, Hainline, Kevin, Haley, Craig, Hami, Maryam, Hamilton, Forrest Clifford, Hammann, Jeffrey, Hammel, Heidi B., Hanley, Christopher J., Hansen, Carl August, Hardy, Bruce, Harnisch, Bernd, Harr, Michael Hunter, Harris, Pamela, Hart, Jessica Ann, Hartig, George F., Hasan, Hashima, Hashim, Kathleen Marie, Hashimoto, Ryan, Haskins, Sujee J., Hawkins, Robert Edward, Hayden, Brian, Hayden, William L., Healy, Mike, Hecht, Karen, Heeg, Vince J., Hejal, Reem, Helm, Kristopher A., Hengemihle, Nicholas J., Henning, Thomas, Henry, Alaina, Henry, Ronald L., Henshaw, Katherine, Hernandez, Scarlin, Herrington, Donald C., Heske, Astrid, Hesman, Brigette Emily, Hickey, David L., Hilbert, Bryan N., Hines, Dean C., Hinz, Michael R., Hirsch, Michael, Hitcho, Robert S., Hodapp, Klaus, Hodge, Philip E., Hoffman, Melissa, Holfeltz, Sherie T., Holler, Bryan Jason, Hoppa, Jennifer Rose, Horner, Scott, Howard, Joseph M., Howard, Richard J., Huber, Jean M., Hunkeler, Joseph S., Hunter, Alexander, Hunter, David Gavin, Hurd, Spencer W., Hurst, Brendan J., Hutchings, John B., Hylan, Jason E., Ignat, Luminita Ilinca, Illingworth, Garth, Irish, Sandra M., Isaacs III, John C., Jackson Jr., Wallace C., Jaffe, Daniel T., Jahic, Jasmin, Jahromi, Amir, Jakobsen, Peter, James, Bryan, James, John C., James, LeAndrea Rae, Jamieson, William Brian, Jandra, Raymond D., Jayawardhana, Ray, Jedrzejewski, Robert, Jeffers, Basil S., Jensen, Peter, Joanne, Egges, Johns, Alan T., Johnson, Carl A., Johnson, Eric L., Johnson, Patricia, Johnson, Phillip Stephen, Johnson, Thomas K., Johnson, Timothy W., Johnstone, Doug, Jollet, Delphine, Jones, Danny P., Jones, Gregory S., Jones, Olivia C., Jones, Ronald A., Jones, Vicki, Jordan, Ian J., Jordan, Margaret E., Jue, Reginald, Jurkowski, Mark H., Justis, Grant, Justtanont, Kay, Kaleida, Catherine C., Kalirai, Jason S., Kalmanson, Phillip Cabrales, Kaltenegger, Lisa, Kammerer, Jens, Kan, Samuel K., Kanarek, Graham Childs, Kao, Shaw-Hong, Karakla, Diane M., Karl, Hermann, Kassin, Susan A., Kauffman, David D., Kavanagh, Patrick, Kelley, Leigh L., Kelly, Douglas M., Kendrew, Sarah, Kennedy, Herbert V., Kenny, Deborah A., Keski-Kuha, Ritva A., Keyes, Charles D., Khan, Ali, Kidwell, Richard C., Kimble, Randy A., King, James S., King, Richard C., Kinzel, Wayne M., Kirk, Jeffrey R., Kirkpatrick, Marc E., Klaassen, Pamela, Klingemann, Lana, Klintworth, Paul U., Knapp, Bryan Adam, Knight, Scott, Knollenberg, Perry J., Knutsen, Daniel Mark, Koehler, Robert, Koekemoer, Anton M., Kofler, Earl T., Kontson, Vicki L., Kovacs, Aiden Rose, Kozhurina-Platais, Vera, Krause, Oliver, Kriss, Gerard A., Krist, John, Kristoffersen, Monica R., Krogel, Claudia, Krueger, Anthony P., Kulp, Bernard A., Kumari, Nimisha, Kwan, Sandy W., Kyprianou, Mark, Labador, Aurora Gadiano, Labiano, Álvaro, Lafrenière, David, Lagage, Pierre-Olivier, Laidler, Victoria G., Laine, Benoit, Laird, Simon, Lajoie, Charles-Philippe, Lallo, Matthew D., Lam, May Yen, LaMassa, Stephanie Marie, Lambros, Scott D., Lampenfield, Richard Joseph, Lander, Matthew Ed, Langston, James Hutton, Larson, Kirsten, Larson, Melora, LaVerghetta, Robert Joseph, Law, David R., Lawrence, Jon F., Lee, David W., Lee, Janice, Lee, Yat-Ning Paul, Leisenring, Jarron, Leveille, Michael Dunlap, Levenson, Nancy A., Levi, Joshua S., Levine, Marie B., Lewis, Dan, Lewis, Jake, Lewis, Nikole, Libralato, Mattia, Lidon, Norbert, Liebrecht, Paula Louisa, Lightsey, Paul, Lilly, Simon, Lim, Frederick C., Lim, Pey Lian, Ling, Sai-Kwong, Link, Lisa J., Link, Miranda Nicole, Lipinski, Jamie L., Liu, XiaoLi, Lo, Amy S., Lobmeyer, Lynette, Logue, Ryan M., Long, Chris A., Long, Douglas R., Long, Ilana D., Long, Knox S., López-Caniego, Marcos, Lotz, Jennifer M., Love-Pruitt, Jennifer M., Lubskiy, Michael, Luers, Edward B., Luetgens, Robert A., Luevano, Annetta J., Lui, Sarah Marie G. Flores, Lund III, James M., Lundquist, Ray A., Lunine, Jonathan, Lützgendorf, Nora, Lynch, Richard J., MacDonald, Alex J., MacDonald, Kenneth, Macias, Matthew J., Macklis, Keith I., Maghami, Peiman, Maharaja, Rishabh Y., Maiolino, Roberto, Makrygiannis, Konstantinos G., Malla, Sunita Giri, Malumuth, Eliot M., Manjavacas, Elena, Marini, Andrea, Marrione, Amanda, Marston, Anthony, Martel, André R, Martin, Didier, Martin, Peter G., Martinez, Kristin L., Maschmann, Marc, Masci, Gregory L., Masetti, Margaret E., Maszkiewicz, Michael, Matthews, Gary, Matuskey, Jacob E., McBrayer, Glen A., McCarthy, Donald W., McCaughrean, Mark J., McClare, Leslie A., McClare, Michael D., McCloskey, John C., McClurg, Taylore D., McCoy, Martin, McElwain, Michael W., McGregor, Roy D., McGuffey, Douglas B., McKay, Andrew G., McKenzie, William K., McLean, Brian, McMaster, Matthew, McNeil, Warren, De Meester, Wim, Mehalick, Kimberly L., Meixner, Margaret, Meléndez, Marcio, Menzel, Michael P., Menzel, Michael T., Merz, Matthew, Mesterharm, David D., Meyer, Michael R., Meyett, Michele L., Meza, Luis E., Midwinter, Calvin, Milam, Stefanie N., Miller, Jay Todd, Miller, William C., Miskey, Cherie L., Misselt, Karl, Mitchell, Eileen P., Mohan, Martin, Montoya, Emily E., Moran, Michael J., Morishita, Takahiro, Moro-Martín, Amaya, Morrison, Debra L., Morrison, Jane, Morse, Ernie C., Moschos, Michael, Moseley, S. H., Mosier, Gary E., Mosner, Peter, Mountain, Matt, Muckenthaler, Jason S., Mueller, Donald G., Mueller, Migo, Muhiem, Daniella, Mühlmann, Prisca, Mullally, Susan Elizabeth, Mullen, Stephanie M., Munger, Alan J, Murphy, Jess, Murray, Katherine T., Muzerolle, James C., Mycroft, Matthew, Myers, Andrew, Myers, Carey R., Myers, Fred Richard R., Myers, Richard, Myrick, Kaila, Nagle IV, Adrian F., Nayak, Omnarayani, Naylor, Bret, Neff, Susan G., Nelan, Edmund P., Nella, John, Nguyen, Duy Tuong, Nguyen, Michael N., Nickson, Bryony, Nidhiry, John Joseph, Niedner, Malcolm B., Nieto-Santisteban, Maria, Nikolov, Nikolay K., Nishisaka, Mary Ann, Nota, Antonella, O'Mara, Robyn C., Oboryshko, Michael, O'Brien, Marcus B., Ochs, William R., Offenberg, Joel D., Ogle, Patrick Michael, Ohl, Raymond G., Olmsted, Joseph Hamden, Osborne, Shannon Barbara, O'Shaughnessy, Brian Patrick, Östlin, Göran, O'Sullivan, Brian, Otor, O. Justin, Ottens, Richard, Ouellette, Nathalie N. -Q., Outlaw, Daria J., Owens, Beverly A., Pacifici, Camilla, Page, James Christophe, Paranilam, James G., Park, Sang, Parrish, Keith A., Paschal, Laura, Patapis, Polychronis, Patel, Jignasha, Patrick, Keith, Pattishall Jr., Robert A., Paul, Douglas William, Paul, Shirley J., Pauly, Tyler Andrew, Pavlovsky, Cheryl M., Peña-Guerrero, Maria, Pedder, Andrew H., Peek, Matthew Weldon, Pelham, Patricia A., Penanen, Konstantin, Perriello, Beth A., Perrin, Marshall D., Perrine, Richard F., Perrygo, Chuck, Peslier, Muriel, Petach, Michael, Peterson, Karla A., Pfarr, Tom, Pierson, James M., Pietraszkiewicz, Martin, Pilchen, Guy, Pipher, Judy L., Pirzkal, Norbert, Pitman, Joseph T., Player, Danielle M., Plesha, Rachel, Plitzke, Anja, Pohner, John A., Poletis, Karyn Konstantin, Pollizzi, Joseph A., Polster, Ethan, Pontius, James T., Pontoppidan, Klaus, Porges, Susana C., Potter, Gregg D., Prescott, Stephen, Proffitt, Charles R., Pueyo, Laurent, Neira, Irma Aracely Quispe, Radich, Armando, Rager, Reiko T., Rameau, Julien, Ramey, Deborah D., Alarcon, Rafael Ramos, Rampini, Riccardo, Rapp, Robert, Rashford, Robert A., Rauscher, Bernard J., Ravindranath, Swara, Rawle, Timothy, Rawlings, Tynika N., Ray, Tom, Regan, Michael W., Rehm, Brian, Rehm, Kenneth D., Reid, Neill, Reis, Carl A., Renk, Florian, Reoch, Tom B., Ressler, Michael, Rest, Armin W., Reynolds, Paul J., Richon, Joel G., Richon, Karen V., Ridgaway, Michael, Riedel, Adric Richard, Rieke, George H., Rieke, Marcia, Rifelli, Richard E., Rigby, Jane R., Riggs, Catherine S., Ringel, Nancy J., Ritchie, Christine E., Rix, Hans-Walter, Robberto, Massimo, Robinson, Michael S., Robinson, Orion, Rock, Frank W., Rodriguez, David R., del Pino, Bruno Rodríguez, Roellig, Thomas, Rohrbach, Scott O., Roman, Anthony J., Romelfanger, Frederick J., Romo Jr., Felipe P., Rosales, Jose J., Rose, Perry, Roteliuk, Anthony F., Roth, Marc N., Rothwell, Braden Quinn, Rouzaud, Sylvain, Rowe, Jason, Rowlands, Neil, Roy, Arpita, Royer, Pierre, Rui, Chunlei, Rumler, Peter, Rumpl, William, Russ, Melissa L., Ryan, Michael B., Ryan, Richard M., Saad, Karl, Sabata, Modhumita, Sabatino, Rick, Sabbi, Elena, Sabelhaus, Phillip A., Sabia, Stephen, Sahu, Kailash C., Saif, Babak N., Salvignol, Jean-Christophe, Samara-Ratna, Piyal, Samuelson, Bridget S., Sanders, Felicia A., Sappington, Bradley, Sargent, B. A., Sauer, Arne, Savadkin, Bruce J., Sawicki, Marcin, Schappell, Tina M., Scheffer, Caroline, Scheithauer, Silvia, Scherer, Ron, Schiff, Conrad, Schlawin, Everett, Schmeitzky, Olivier, Schmitz, Tyler S., Schmude, Donald J., Schneider, Analyn, Schreiber, Jürgen, Schroeven-Deceuninck, Hilde, Schultz, John J., Schwab, Ryan, Schwartz, Curtis H., Scoccimarro, Dario, Scott, John F., Scott, Michelle B., Seaton, Bonita L., Seely, Bruce S., Seery, Bernard, Seidleck, Mark, Sembach, Kenneth, Shanahan, Clare Elizabeth, Shaughnessy, Bryan, Shaw, Richard A., Shay, Christopher Michael, Sheehan, Even, Sheth, Kartik, Shih, Hsin-Yi, Shivaei, Irene, Siegel, Noah, Sienkiewicz, Matthew G., Simmons, Debra D., Simon, Bernard P., Sirianni, Marco, Sivaramakrishnan, Anand, Slade, Jeffrey E., Sloan, G. C., Slocum, Christine E., Slowinski, Steven E., Smith, Corbett T., Smith, Eric P., Smith, Erin C., Smith, Koby, Smith, Robert, Smith, Stephanie J., Smolik, John L., Soderblom, David R., Sohn, Sangmo Tony, Sokol, Jeff, Sonneborn, George, Sontag, Christopher D., Sooy, Peter R., Soummer, Remi, Southwood, Dana M., Spain, Kay, Sparmo, Joseph, Speer, David T., Spencer, Richard, Sprofera, Joseph D., Stallcup, Scott S., Stanley, Marcia K., Stansberry, John A., Stark, Christopher C., Starr, Carl W., Stassi, Diane Y., Steck, Jane A., Steeley, Christine D., Stephens, Matthew A., Stephenson, Ralph J., Stewart, Alphonso C., Stiavelli, Massimo, Stockman Jr., Hervey, Strada, Paolo, Straughn, Amber N., Streetman, Scott, Strickland, David Kendal, Strobele, Jingping F., Stuhlinger, Martin, Stys, Jeffrey Edward, Such, Miguel, Sukhatme, Kalyani, Sullivan, Joseph F., Sullivan, Pamela C., Sumner, Sandra M., Sun, Fengwu, Sunnquist, Benjamin Dale, Swade, Daryl Allen, Swam, Michael S., Swenton, Diane F., Swoish, Robby A., Litten, Oi In Tam, Tamas, Laszlo, Tao, Andrew, Taylor, David K., Taylor, Joanna M., Plate, Maurice te, Van Tea, Mason, Teague, Kelly K., Telfer, Randal C., Temim, Tea, Texter, Scott C., Thatte, Deepashri G., Thompson, Christopher Lee, Thompson, Linda M., Thomson, Shaun R., Thronson, Harley, Tierney, C. M., Tikkanen, Tuomo, Tinnin, Lee, Tippet, William Thomas, Todd, Connor William, Tran, Hien D., Trauger, John, Trejo, Edwin Gregorio, Truong, Justin Hoang Vinh, Tsukamoto, Christine L., Tufail, Yasir, Tumlinson, Jason, Tustain, Samuel, Tyra, Harrison, Ubeda, Leonardo, Underwood, Kelli, Uzzo, Michael A., Vaclavik, Steven, Valenduc, Frida, Valenti, Jeff A., Van Campen, Julie, van de Wetering, Inge, Van Der Marel, Roeland P., van Haarlem, Remy, Vandenbussche, Bart, Vanterpool, Dona D., Vernoy, Michael R., Costas, Maria Begoña Vila, Volk, Kevin, Voorzaat, Piet, Voyton, Mark F., Vydra, Ekaterina, Waddy, Darryl J., Waelkens, Christoffel, Wahlgren, Glenn Michael, Walker Jr., Frederick E., Wander, Michel, Warfield, Christine K., Warner, Gerald, Wasiak, Francis C., Wasiak, Matthew F., Wehner, James, Weiler, Kevin R., Weilert, Mark, Weiss, Stanley B., Wells, Martyn, Welty, Alan D., Wheate, Lauren, Wheeler, Thomas P., White, Christy L., Whitehouse, Paul, Whiteleather, Jennifer Margaret, Whitman, William Russell, Williams, Christina C., Willmer, Christopher N. A., Willott, Chris J., Willoughby, Scott P., Wilson, Andrew, Wilson, Debra, Wilson, Donna V., Windhorst, Rogier, Wislowski, Emily Christine, Wolfe, David J., Wolfe, Michael A., Wolff, Schuyler, Wondel, Amancio, Woo, Cindy, Woods, Robert T., Worden, Elaine, Workman, William, Wright, Gillian S., Wu, Carl, Wu, Chi-Rai, Wun, Dakin D., Wymer, Kristen B., Yadetie, Thomas, Yan, Isabelle C., Yang, Keith C., Yates, Kayla L., Yeager, Christopher R., Yerger, Ethan John, Young, Erick T., Young, Gary, Yu, Gene, Yu, Susan, Zak, Dean S., Zeidler, Peter, Zepp, Robert, Zhou, Julia, Zincke, Christian A., Zonak, Stephanie, and Zondag, Elisabeth
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Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
Twenty-six years ago a small committee report, building on earlier studies, expounded a compelling and poetic vision for the future of astronomy, calling for an infrared-optimized space telescope with an aperture of at least $4m$. With the support of their governments in the US, Europe, and Canada, 20,000 people realized that vision as the $6.5m$ James Webb Space Telescope. A generation of astronomers will celebrate their accomplishments for the life of the mission, potentially as long as 20 years, and beyond. This report and the scientific discoveries that follow are extended thank-you notes to the 20,000 team members. The telescope is working perfectly, with much better image quality than expected. In this and accompanying papers, we give a brief history, describe the observatory, outline its objectives and current observing program, and discuss the inventions and people who made it possible. We cite detailed reports on the design and the measured performance on orbit., Comment: Accepted by PASP for the special issue on The James Webb Space Telescope Overview, 29 pages, 4 figures
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- 2023
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16. From Compact Plasma Particle Sources to Advanced Accelerators with Modeling at Exascale
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Huebl, Axel, Lehe, Remi, Zoni, Edoardo, Shapoval, Olga, Sandberg, Ryan T., Garten, Marco, Formenti, Arianna, Jambunathan, Revathi, Kumar, Prabhat, Gott, Kevin, Myers, Andrew, Zhang, Weiqun, Almgren, Ann, Mitchell, Chad E., Qiang, Ji, Grote, David, Sinn, Alexander, Diederichs, Severin, Thevenet, Maxence, Fedeli, Luca, Clark, Thomas, Zaim, Neil, Vincenti, Henri, and Vay, Jean-Luc
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Physics - Accelerator Physics ,Computer Science - Software Engineering ,Physics - Plasma Physics - Abstract
Developing complex, reliable advanced accelerators requires a coordinated, extensible, and comprehensive approach in modeling, from source to the end of beam lifetime. We present highlights in Exascale Computing to scale accelerator modeling software to the requirements set for contemporary science drivers. In particular, we present the first laser-plasma modeling on an exaflop supercomputer using the US DOE Exascale Computing Project WarpX. Leveraging developments for Exascale, the new DOE SCIDAC-5 Consortium for Advanced Modeling of Particle Accelerators (CAMPA) will advance numerical algorithms and accelerate community modeling codes in a cohesive manner: from beam source, over energy boost, transport, injection, storage, to application or interaction. Such start-to-end modeling will enable the exploration of hybrid accelerators, with conventional and advanced elements, as the next step for advanced accelerator modeling. Following open community standards, we seed an open ecosystem of codes that can be readily combined with each other and machine learning frameworks. These will cover ultrafast to ultraprecise modeling for future hybrid accelerator design, even enabling virtual test stands and twins of accelerators that can be used in operations., Comment: 4 pages, 3 figures, presented at the 20th Advanced Accelerator Concepts Workshop (AAC22)
- Published
- 2023
17. Cold War Dixie: Militarization and Modernization in the American South by Kari Frederickson (review)
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Myers, Andrew H.
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- 2014
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18. Stanford researchers say school kids can do safe and simple biological experiments over the internet
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Myers, Andrew
- Published
- 2017
19. Ebola: Virology, Clinical Considerations, and Outbreak Response and Prevention
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Oxner, Asa, Myers, Andrew, Somboonwit, Charurut, editor, Shapshak, Paul, editor, Kangueane, Pandjassarame, editor, Balaji, S., editor, Sinnott, John T., editor, Menezes, Lynette J., editor, and Oxner, Asa, editor
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- 2024
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20. BMX: Biological modelling and interface exchange
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Palmer, Bruce J, Almgren, Ann S, Johnson, Connah GM, Myers, Andrew T, and Cannon, William R
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Information and Computing Sciences ,Biological Sciences ,Applied Computing ,Software ,Computing Methodologies ,Bacteria - Abstract
High performance computing has a great potential to provide a range of significant benefits for investigating biological systems. These systems often present large modelling problems with many coupled subsystems, such as when studying colonies of bacteria cells. The aim to understand cell colonies has generated substantial interest as they can have strong economic and societal impacts through their roles in in industrial bioreactors and complex community structures, called biofilms, found in clinical settings. Investigating these communities through realistic models can rapidly exceed the capabilities of current serial software. Here, we introduce BMX, a software system developed for the high performance modelling of large cell communities by utilising GPU acceleration. BMX builds upon the AMRex adaptive mesh refinement package to efficiently model cell colony formation under realistic laboratory conditions. Using simple test scenarios with varying nutrient availability, we show that BMX is capable of correctly reproducing observed behavior of bacterial colonies on realistic time scales demonstrating a potential application of high performance computing to colony modelling. The open source software is available from the zenodo repository https://doi.org/10.5281/zenodo.8084270 under the BSD-2-Clause licence.
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- 2023
21. Pushing the Frontier in the Design of Laser-Based Electron Accelerators with Groundbreaking Mesh-Refined Particle-In-Cell Simulations on Exascale-Class Supercomputers
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Fedeli, Luca, Huebl, Axel, Boillod-Cerneux, France, Clark, Thomas, Gott, Kevin, Hillairet, Conrad, Jaure, Stephan, Leblanc, Adrien, Lehe, Rémi, Myers, Andrew, Piechurski, Christelle, Sato, Mitsuhisa, Zaim, Neïl, Zhang, Weiqun, Vay, Jean-Luc, and Vincenti, Henri
- Abstract
(150 word max) We present a first-of-kind mesh-refined (MR) massively parallel Particle-In-Cell (PIC) code for kinetic plasma simulations optimized on the Frontier, Fugaku, Summit, and Perlmutter supercomputers. Major innovations, implemented in the WarpX PIC code, include: (i) a three level parallelization strategy that demonstrated performance portability and scaling on millions of A64FX cores and tens of thousands of AMD and Nvidia GPUs (ii) a groundbreaking mesh refinement capability that provides between 1.5 x to 4 x savings in computing requirements on the science case reported in this paper, (iii) an efficient load balancing strategy between multiple MR levels. The MR PIC code enabled 3D simulations of laser-matter interactions on Frontier, Fugaku, and Summit, which have so far been out of the reach of standard codes. These simulations helped remove a major limitation of compact laser-based electron accelerators, which are promising candidates for next generation high-energy physics experiments and ultra-high dose rate FLASH radiotherapy.
- Published
- 2022
22. Invisible disabilities and college academic success: New evidence from a mediation analysis
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Myers, Andrew, Halpern-Manners, Andrew, and McLeod, Jane D.
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- 2024
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23. A flexible type system for fearless concurrency
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Milano, Mae, Turcotti, Joshua, and Myers, Andrew C
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Information and Computing Sciences ,Software Engineering ,concurrency ,type systems ,aliasing - Published
- 2022
24. PICSAR-QED: a Monte Carlo module to simulate Strong-Field Quantum Electrodynamics in Particle-In-Cell codes for exascale architectures
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Fedeli, Luca, Zaïm, Neïl, Sainte-Marie, Antonin, Thévenet, Maxence, Huebl, Axel, Myers, Andrew, Vay, Jean-Luc, and Vincenti, Henri
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Physics - Plasma Physics ,Physics - Computational Physics - Abstract
Physical scenarios where the electromagnetic fields are so strong that Quantum ElectroDynamics (QED) plays a substantial role are one of the frontiers of contemporary plasma physics research. Investigating those scenarios requires state-of-the-art Particle-In-Cell (PIC) codes able to run on top high-performance computing machines and, at the same time, able to simulate strong-field QED processes. This work presents the PICSAR-QED library, an open-source, portable implementation of a Monte Carlo module designed to provide modern PIC codes with the capability to simulate such processes, and optimized for high-performance computing. Detailed tests and benchmarks are carried out to validate the physical models in PICSAR-QED, to study how numerical parameters affect such models, and to demonstrate its capability to run on different architectures (CPUs and GPUs). Its integration with WarpX, a state-of-the-art PIC code designed to deliver scalable performance on upcoming exascale supercomputers, is also discussed and validated against results from the existing literature., Comment: 33 pages, 7 figures, 4 tables
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- 2021
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25. HiPACE++: a portable, 3D quasi-static Particle-in-Cell code
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Diederichs, Severin, Benedetti, Carlo, Huebl, Axel, Lehe, Rémi, Myers, Andrew, Sinn, Alexander, Vay, Jean-Luc, Zhang, Weiqun, and Thévenet, Maxence
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Physics - Computational Physics ,Physics - Accelerator Physics ,Physics - Plasma Physics - Abstract
Modeling plasma accelerators is a computationally challenging task and the quasi-static particle-in-cell algorithm is a method of choice in a wide range of situations. In this work, we present the first performance-portable, quasi-static, three-dimensional particle-in-cell code HiPACE++. By decomposing all the computation of a 3D domain in successive 2D transverse operations and choosing appropriate memory management, HiPACE++ demonstrates orders-of-magnitude speedups on modern scientific GPUs over CPU-only implementations. The 2D transverse operations are performed on a single GPU, avoiding time-consuming communications. The longitudinal parallelization is done through temporal domain decomposition, enabling near-optimal strong scaling from 1 to 512 GPUs. HiPACE++ is a modular, open-source code enabling efficient modeling of plasma accelerators from laptops to state-of-the-art supercomputers.
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- 2021
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26. Reference monopile designs for US East Coast sites supporting the IEA 15 MW reference turbine using a novel conceptual design methodology
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Mroczek, Maciej M., Arwade, Sanjay Raja, Davis, Michael, Hallowell, Spencer, Myers, Andrew, Riyanto, Raditya Danu, and Pang, Weichiang
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- 2024
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27. PICSAR-QED: a Monte Carlo module to simulate strong-field quantum electrodynamics in particle-in-cell codes for exascale architectures
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Fedeli, Luca, Zaïm, Neïl, Sainte-Marie, Antonin, Thévenet, Maxence, Huebl, Axel, Myers, Andrew, Vay, Jean-Luc, and Vincenti, Henri
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strong-field QED ,particle-in-cell codes ,nonlinear Breit-Wheeler pair production ,inverse Compton photon emission ,Monte Carlo methods ,exascale supercomputing ,Physical Sciences ,Fluids & Plasmas - Abstract
Physical scenarios where the electromagnetic fields are so strong that quantum electrodynamics (QED) plays a substantial role are one of the frontiers of contemporary plasma physics research. Investigating those scenarios requires state-of-the-art particle-in-cell (PIC) codes able to run on top high-performance computing (HPC) machines and, at the same time, able to simulate strong-field QED processes. This work presents the PICSAR-QED library, an open-source, portable implementation of a Monte Carlo module designed to provide modern PIC codes with the capability to simulate such processes, and optimized for HPC. Detailed tests and benchmarks are carried out to validate the physical models in PICSAR-QED, to study how numerical parameters affect such models, and to demonstrate its capability to run on different architectures (CPUs and GPUs). Its integration with WarpX, a state-of-the-art PIC code designed to deliver scalable performance on upcoming exascale supercomputers, is also discussed and validated against results from the existing literature.
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- 2022
28. MFIX-Exa: A path toward exascale CFD-DEM simulations
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Musser, Jordan, Almgren, Ann S, Fullmer, William D, Antepara, Oscar, Bell, John B, Blaschke, Johannes, Gott, Kevin, Myers, Andrew, Porcu, Roberto, Rangarajan, Deepak, Rosso, Michele, Zhang, Weiqun, and Syamlal, Madhava
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Information and Computing Sciences ,Applied Computing ,CFD-DEM ,MFIX ,AMReX ,HPC ,exascale ,ECP ,embedded boundaries ,multiphase ,method-of-lines ,Distributed Computing ,Applied computing ,Distributed computing and systems software - Abstract
MFIX-Exa is a computational fluid dynamics–discrete element model (CFD-DEM) code designed to run efficiently on current and next-generation supercomputing architectures. MFIX-Exa combines the CFD-DEM expertise embodied in the MFIX code—which was developed at NETL and is used widely in academia and industry—with the modern software framework, AMReX, developed at LBNL. The fundamental physics models follow those of the original MFIX, but the combination of new algorithmic approaches and a new software infrastructure will enable MFIX-Exa to leverage future exascale machines to optimize the modeling and design of multiphase chemical reactors.
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- 2022
29. A Calculus for Flow-Limited Authorization
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Arden, Owen, Gollamudi, Anitha, Cecchetti, Ethan, Chong, Stephen, and Myers, Andrew C.
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Computer Science - Cryptography and Security ,Computer Science - Programming Languages ,F.3.1 ,F.3.2 ,D.4.6 - Abstract
Real-world applications routinely make authorization decisions based on dynamic computation. Reasoning about dynamically computed authority is challenging. Integrity of the system might be compromised if attackers can improperly influence the authorizing computation. Confidentiality can also be compromised by authorization, since authorization decisions are often based on sensitive data such as membership lists and passwords. Previous formal models for authorization do not fully address the security implications of permitting trust relationships to change, which limits their ability to reason about authority that derives from dynamic computation. Our goal is an approach to constructing dynamic authorization mechanisms that do not violate confidentiality or integrity. The Flow-Limited Authorization Calculus (FLAC) is a simple, expressive model for reasoning about dynamic authorization as well as an information flow control language for securely implementing various authorization mechanisms. FLAC combines the insights of two previous models: it extends the Dependency Core Calculus with features made possible by the Flow-Limited Authorization Model. FLAC provides strong end-to-end information security guarantees even for programs that incorporate and implement rich dynamic authorization mechanisms. These guarantees include noninterference and robust declassification, which prevent attackers from influencing information disclosures in unauthorized ways. We prove these security properties formally for all FLAC programs and explore the expressiveness of FLAC with several examples., Comment: 58 pages
- Published
- 2021
30. Compositional Security for Reentrant Applications
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Cecchetti, Ethan, Yao, Siqiu, Ni, Haobin, and Myers, Andrew C.
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Computer Science - Cryptography and Security ,Computer Science - Programming Languages ,D.4.6 - Abstract
The disastrous vulnerabilities in smart contracts sharply remind us of our ignorance: we do not know how to write code that is secure in composition with malicious code. Information flow control has long been proposed as a way to achieve compositional security, offering strong guarantees even when combining software from different trust domains. Unfortunately, this appealing story breaks down in the presence of reentrancy attacks. We formalize a general definition of reentrancy and introduce a security condition that allows software modules like smart contracts to protect their key invariants while retaining the expressive power of safe forms of reentrancy. We present a security type system that provably enforces secure information flow; in conjunction with run-time mechanisms, it enforces secure reentrancy even in the presence of unknown code; and it helps locate and correct recent high-profile vulnerabilities.
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- 2021
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31. Particle-in-cell Simulation of the Neutrino Fast Flavor Instability
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Richers, Sherwood, Willcox, Don E., Ford, Nicole M., and Myers, Andrew
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Astrophysics - High Energy Astrophysical Phenomena ,Physics - Plasma Physics - Abstract
Neutrinos drive core-collapse supernovae, launch outflows from neutron star merger accretion disks, and set the ratio of protons to neutrons in ejecta from both systems that generate heavy elements in the universe. Neutrinos of different flavors interact with matter differently, and much recent work has suggested that fast flavor instabilities are likely ubiquitous in both systems, but the final flavor content after the instability saturates has not been well understood. In this work we present particle-in-cell calculations which follow the evolution of all flavors of neutrinos and antineutrinos through saturation and kinematic decoherence. We conduct one-dimensional three-flavor simulations of neutrino quantum kinetics to demonstrate the outcome of this instability in a few example cases. We demonstrate the growth of both axially symmetric and asymmetric modes whose wavelength and growth rate match predictions from linear stability analysis. Finally, we vary the number density, flux magnitude, and flux direction of the neutrinos and antineutrinos and demonstrate that these factors modify both the growth rate and post-saturation neutrino flavor abundances. Weak electron lepton number (ELN) crossings in these simulations produce both slow growth of the instability and little difference between the flavor abundances in the initial and final states. In all of these calculations the same number of neutrinos and antineutrinos change flavor, making the least abundant between them the limiting factor for post-saturation flavor change. Many more simulations and multi-dimensional simulations are needed to fully probe the parameter space of the initial conditions., Comment: 15 pages, 10 figures, plus references and appendices. Accepted to PRD
- Published
- 2021
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32. Probing strong-field QED with Doppler-boosted PetaWatt-class lasers
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Fedeli, Luca, Sainte-Marie, Antonin, Zaïm, Neil, Thévenet, Maxence, Vay, Jean-Luc, Myers, Andrew, Quéré, Fabien, and Vincenti, Henri
- Subjects
Physics - Plasma Physics - Abstract
We propose a scheme to explore regimes of strong-field Quantum Electrodynamics (SF-QED) otherwise unattainable with the currently available laser technology. The scheme relies on relativistic plasma mirrors curved by radiation pressure to boost the intensity of PetaWatt-class laser pulses by Doppler effect and focus them to extreme field intensities. We show that very clear SF-QED signatures could be observed by placing a secondary target where the boosted beam is focused., Comment: 5 figures
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- 2020
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33. Heterogeneous Paxos: Technical Report
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Sheff, Isaac, Wang, Xinwen, van Renesse, Robbert, and Myers, Andrew C.
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Computer Science - Distributed, Parallel, and Cluster Computing ,Computer Science - Cryptography and Security ,Computer Science - Databases - Abstract
In distributed systems, a group of $\textit{learners}$ achieve $\textit{consensus}$ when, by observing the output of some $\textit{acceptors}$, they all arrive at the same value. Consensus is crucial for ordering transactions in failure-tolerant systems. Traditional consensus algorithms are homogeneous in three ways: - all learners are treated equally, - all acceptors are treated equally, and - all failures are treated equally. These assumptions, however, are unsuitable for cross-domain applications, including blockchains, where not all acceptors are equally trustworthy, and not all learners have the same assumptions and priorities. We present the first consensus algorithm to be heterogeneous in all three respects. Learners set their own mixed failure tolerances over differently trusted sets of acceptors. We express these assumptions in a novel $\textit{Learner Graph}$, and demonstrate sufficient conditions for consensus. We present $\textit{Heterogeneous Paxos}$: an extension of Byzantine Paxos. Heterogeneous Paxos achieves consensus for any viable Learner Graph in best-case three message sends, which is optimal. We present a proof-of-concept implementation, and demonstrate how tailoring for heterogeneous scenarios can save resources and latency.
- Published
- 2020
34. Implementation of an Electronic Medical Record Alert Significantly Increases Lung Cancer Screening Uptake
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Park, Ju Ae, Yalamanchili, Sriya, Brown, Zeliene, Myers, Andrew, Weyant, Michael J., Mahajan, Amit K., Connolly, Christopher Patrick, and Suzuki, Kei
- Published
- 2024
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35. The hidden crisis: Long COVID's association with housing stability and home accessibility among people with disabilities
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Goddard, Kelsey, Myers, Andrew, and Ipsen, Catherine
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- 2024
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36. “Patiently waiting”: How do non-driving disabled adults get around in rural America?
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Myers, Andrew and Standley, Krys
- Published
- 2024
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37. Handling Bidirectional Control Flow: Technical Report
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Zhang, Yizhou, Salvaneschi, Guido, and Myers, Andrew C.
- Subjects
Computer Science - Programming Languages - Abstract
Pressed by the difficulty of writing asynchronous, event-driven code, mainstream languages have recently been building in support for a variety of advanced control-flow features. Meanwhile, experimental language designs have suggested effect handlers as a unifying solution to programmer-defined control effects, subsuming exceptions, generators, and async--await. Despite these trends, complex control flow---in particular, control flow exhibiting a bidirectional pattern---remains challenging to manage. We introduce bidirectional algebraic effects, a new programming abstraction that supports bidirectional control transfer in a more natural way. Handlers of bidirectional effects can raise further effects to transfer control back to the site where the initiating effect was raised, and can use themselves to handle their own effects. We present applications of this expressive power, which falls out naturally as we push toward the unification of effectful programming with object-oriented programming. We pin down the mechanism and the unification formally using a core language that generalizes to effect operations and effect handlers. The usual propagation semantics of control effects such as exceptions conflicts with modular reasoning in the presence of effect polymorphism---it breaks parametricity. Bidirectionality exacerbates the problem. Hence, we set out to show the core language, which builds on the existing tunneling semantics for algebraic effects, is not only type-safe (no effects go unhandled), but also abstraction-safe (no effects are accidentally handled). We devise a step-indexed logical-relations model, and construct its parametricity and soundness proofs. These core results are fully mechanized in Coq. Preliminary experiments show that as a first-class language feature, bidirectional handlers can be implemented efficiently., Comment: Technical report of paper "Handling Bidirectional Control Flow" (OOPSLA 2020)
- Published
- 2020
38. AMReX: Block-Structured Adaptive Mesh Refinement for Multiphysics Applications
- Author
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Zhang, Weiqun, Myers, Andrew, Gott, Kevin, Almgren, Ann, and Bell, John
- Subjects
Computer Science - Mathematical Software ,Computer Science - Computational Engineering, Finance, and Science ,Computer Science - Distributed, Parallel, and Cluster Computing - Abstract
Block-structured adaptive mesh refinement (AMR) provides the basis for the temporal and spatial discretization strategy for a number of ECP applications in the areas of accelerator design, additive manufacturing, astrophysics, combustion, cosmology, multiphase flow, and wind plant modelling. AMReX is a software framework that provides a unified infrastructure with the functionality needed for these and other AMR applications to be able to effectively and efficiently utilize machines from laptops to exascale architectures. AMR reduces the computational cost and memory footprint compared to a uniform mesh while preserving accurate descriptions of different physical processes in complex multi-physics algorithms. AMReX supports algorithms that solve systems of partial differential equations (PDEs) in simple or complex geometries, and those that use particles and/or particle-mesh operations to represent component physical processes. In this paper, we will discuss the core elements of the AMReX framework such as data containers and iterators as well as several specialized operations to meet the needs of the application projects. In addition we will highlight the strategy that the AMReX team is pursuing to achieve highly performant code across a range of accelerator-based architectures for a variety of different applications., Comment: 16 pages, 9 figures, submitted to IJHPCA
- Published
- 2020
39. The Cost of Software-Based Memory Management Without Virtual Memory
- Author
-
Zagieboylo, Drew, Suh, G. Edward, and Myers, Andrew C.
- Subjects
Computer Science - Hardware Architecture ,Computer Science - Programming Languages - Abstract
Virtual memory has been a standard hardware feature for more than three decades. At the price of increased hardware complexity, it has simplified software and promised strong isolation among colocated processes. In modern computing systems, however, the costs of virtual memory have increased significantly. With large memory workloads, virtualized environments, data center computing, and chips with multiple DMA devices, virtual memory can degrade performance and increase power usage. We therefore explore the implications of building applications and operating systems without relying on hardware support for address translation. Primarily, we investigate the implications of removing the abstraction of large contiguous memory segments. Our experiments show that the overhead to remove this reliance is surprisingly small for real programs. We expect this small overhead to be worth the benefit of reducing the complexity and energy usage of address translation. In fact, in some cases, performance can even improve when address translation is avoided.
- Published
- 2020
40. Nyx: A Massively Parallel AMR Code for Computational Cosmology
- Author
-
Sexton, Jean, Lukic, Zarija, Almgren, Ann, Daley, Chris, Friesen, Brian, Myers, Andrew, and Zhang, Weiqun
- Subjects
Information and Computing Sciences ,Information and computing sciences - Published
- 2021
41. Charlotte: Composable Authenticated Distributed Data Structures, Technical Report
- Author
-
Sheff, Isaac, Wang, Xinwen, Ni, Haobin, van Renesse, Robbert, and Myers, Andrew C.
- Subjects
Computer Science - Distributed, Parallel, and Cluster Computing ,Computer Science - Cryptography and Security - Abstract
We present Charlotte, a framework for composable, authenticated distributed data structures. Charlotte data is stored in blocks that reference each other by hash. Together, all Charlotte blocks form a directed acyclic graph, the blockweb; all observers and applications use subgraphs of the blockweb for their own data structures. Unlike prior systems, Charlotte data structures are composable: applications and data structures can operate fully independently when possible, and share blocks when desired. To support this composability, we define a language-independent format for Charlotte blocks and a network API for Charlotte servers. An authenticated distributed data structure guarantees that data is immutable and self-authenticating: data referenced will be unchanged when it is retrieved. Charlotte extends these guarantees by allowing applications to plug in their own mechanisms for ensuring availability and integrity of data structures. Unlike most traditional distributed systems, including distributed databases, blockchains, and distributed hash tables, Charlotte supports heterogeneous trust: different observers may have their own beliefs about who might fail, and how. Despite heterogeneity of trust, Charlotte presents each observer with a consistent, available view of data. We demonstrate the flexibility of Charlotte by implementing a variety of integrity mechanisms, including consensus and proof of work. We study the power of disentangling availability and integrity mechanisms by building a variety of applications. The results from these examples suggest that developers can use Charlotte to build flexible, fast, composable applications with strong guarantees.
- Published
- 2019
42. Development and Implementation of Integrated Radiologist-Speech Pathologist Report for Modified Barium Swallow Study: Experience at a Multi-hospital Single Health Care System
- Author
-
Doddi, Sishir, Bera, Kaustav, Myers, Andrew, Ramaiya, Nikhil, and Tirumani, Sree Harsha
- Published
- 2023
- Full Text
- View/download PDF
43. ESG in Growth Listed Companies: Closing the Gaps
- Author
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Morais, Filipe, Simnett, Jenny, Kakabadse, Andrew, Kakabadse, Nada, Myers, Andrew, Ward, Tim, Câmara, Paulo, editor, and Morais, Filipe, editor
- Published
- 2022
- Full Text
- View/download PDF
44. The humanizing effect of market interaction
- Author
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Harris, Colin, Myers, Andrew, and Kaiser, Adam
- Published
- 2023
- Full Text
- View/download PDF
45. Synthesizing Particle-In-Cell Simulations through Learning and GPU Computing for Hybrid Particle Accelerator Beamlines
- Author
-
Sandberg, Ryan, primary, Lehe, Remi, additional, Mitchell, Chad, additional, Garten, Marco, additional, Myers, Andrew, additional, Qiang, Ji, additional, Vay, Jean-Luc, additional, and Huebl, Axel, additional
- Published
- 2024
- Full Text
- View/download PDF
46. A Case of Scedosporium prolificans Pulmonary Infection in a Patient with Acute Myeloid Leukemia
- Author
-
Arjomand, Abdullah, primary, Myers, Andrew, additional, and Akella, Padmastuti, additional
- Published
- 2024
- Full Text
- View/download PDF
47. A Web of Blocks
- Author
-
Sheff, Isaac, Wang, Xinwen, Myers, Andrew C., and van Renesse, Robbert
- Subjects
Computer Science - Distributed, Parallel, and Cluster Computing ,Computer Science - Databases - Abstract
Blockchains offer a useful abstraction: a trustworthy, decentralized log of totally ordered transactions. Traditional blockchains have problems with scalability and efficiency, preventing their use for many applications. These limitations arise from the requirement that all participants agree on the total ordering of transactions. To address this fundamental shortcoming, we introduce Charlotte, a system for maintaining decentralized, authenticated data structures, including transaction logs. Each data structurestructure -- indeed, each block -- specifies its own availability and integrity properties, allowing Charlotte applications to retain the full benefits of permissioned or permissionless blockchains. In Charlotte, a block can be atomically appended to multiple logs, allowing applications to be interoperable when they want to, without inefficiently forcing all applications to share one big log. We call this open graph of interconnected blocks a blockweb. We allow new kinds of blockweb applications that operate beyond traditional chains. We demonstrate the viability of Charlotte applications with proof-of-concept servers running interoperable blockchains. Using performance data from our prototype, we estimate that when compared with traditional blockchains, Charlotte offers multiple orders of magnitude improvement in speed and energy efficiency.
- Published
- 2018
48. AMReX: a framework for block-structured adaptive mesh refinement
- Author
-
Zhang, Weiqun, Almgren, Ann, Beckner, Vince, Bell, John, Blaschke, Johannes, Chan, Cy, Day, Marcus, Friesen, Brian, Gott, Kevin, Graves, Daniel, Katz, Max, Myers, Andrew, Nguyen, Tan, Nonaka, Andrew, Rosso, Michele, Williams, Samuel, and Zingale, Michael
- Subjects
Information and Computing Sciences ,Information and computing sciences - Published
- 2019
49. Tetracyclines Modify Translation by Targeting Key Human rRNA Substructures
- Author
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Mortison, Jonathan D, Schenone, Monica, Myers, Jacob A, Zhang, Ziyang, Chen, Linfeng, Ciarlo, Christie, Comer, Eamon, Natchiar, S Kundhavai, Carr, Steven A, Klaholz, Bruno P, and Myers, Andrew G
- Subjects
Biochemistry and Cell Biology ,Biological Sciences ,Cancer ,Biotechnology ,Generic health relevance ,Cell Line ,Tumor ,Dose-Response Relationship ,Drug ,Humans ,Models ,Molecular ,Molecular Structure ,Protein Biosynthesis ,RNA ,Ribosomal ,Ribosomes ,Structure-Activity Relationship ,Tetracyclines ,RNA-seq ,chemoproteomics ,diazirine ,photocrosslinking ,ribosome ,target identification ,tetracyclines ,translation ,Biochemistry and cell biology ,Medicinal and biomolecular chemistry - Abstract
Apart from their antimicrobial properties, tetracyclines demonstrate clinically validated effects in the amelioration of pathological inflammation and human cancer. Delineation of the target(s) and mechanism(s) responsible for these effects, however, has remained elusive. Here, employing quantitative mass spectrometry-based proteomics, we identified human 80S ribosomes as targets of the tetracyclines Col-3 and doxycycline. We then developed in-cell click selective crosslinking with RNA sequence profiling (icCL-seq) to map binding sites for these tetracyclines on key human rRNA substructures at nucleotide resolution. Importantly, we found that structurally and phenotypically variant tetracycline analogs could chemically discriminate these rRNA binding sites. We also found that tetracyclines both subtly modify human ribosomal translation and selectively activate the cellular integrated stress response (ISR). Together, the data reveal that targeting of specific rRNA substructures, activation of the ISR, and inhibition of translation are correlated with the anti-proliferative properties of tetracyclines in human cancer cell lines.
- Published
- 2018
50. Python-based in situ analysis and visualization
- Author
-
Loring, Burlen, Myers, Andrew, Camp, David, and Bethel, E Wes
- Subjects
Information and Computing Sciences ,Applied Computing ,Python ,in situ analysis ,in situ visualization - Abstract
This work focuses on enabling the use of Python-based methods for the purpose of performing in situ analysis and visualization. This approach facilitates access to and use of a rapidly growing collection of Python-based, third-party libraries for analysis and visualization, as well as lowering the barrier to entry for user-written Python analysis codes. Beginning with a simulation code that is instrumented to use the SENSEI in situ interface, we present how to couple it with a Python-based data consumer, which may be run in situ, and in parallel at the same concurrency as the simulation. We present two examples that demonstrate the new capability. One is an analysis of the reaction rate in a proxy simulation of a chemical reaction on a 2D substrate, while the other is a coupling of an AMR simulation to Yt, a parallel visualization and analysis library written in Python. In the examples, both the simulation and Python in situ method run in parallel on a large-scale HPC platform.
- Published
- 2018
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