574 results on '"Myllyharju Johanna"'
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2. Optimisation of substrate feeding in shake flask cultures of Pichia pastoris for recombinant protein production
3. Collagen prolyl 4-hydroxylase isoenzymes I and II have sequence specificity towards different X-Pro-Gly triplets
4. Sandwich ELISA for quantitative detection of human collagen prolyl 4-hydroxylase
5. Improved production of human type II procollagen in the yeast Pichia pastoris in shake flasks by a wireless-controlled fed-batch system
6. Type I and type V procollagen triple helix uses different subsets of the molecular ensemble for lysine posttranslational modifications in the rER
7. Crystal structure of the collagen prolyl 4-hydroxylase (C-P4H) catalytic domain complexed with PDI: Toward a model of the C-P4H α2β2 tetramer
8. Contribution of HIF-P4H isoenzyme inhibition to metabolism indicates major beneficial effects being conveyed by HIF-P4H-2 antagonism
9. PHD2 deletion in endothelial or arterial smooth muscle cells reveals vascular cell type-specific responses in pulmonary hypertension and fibrosis
10. Deletion of hypoxia-inducible factor prolyl 4-hydroxylase 2 in FoxD1-lineage mesenchymal cells leads to congenital truncal alopecia
11. Activation of the hypoxia response pathway protects against age-induced cardiac hypertrophy
12. Inactivation of mouse transmembrane prolyl 4-hydroxylase increases blood brain barrier permeability and ischemia-induced cerebral neuroinflammation
13. Activation of the hypoxia response protects mice from amyloid-β accumulation
14. Structure of transmembrane prolyl 4-hydroxylase reveals unique organization of EF and dioxygenase domains
15. The glucose-sensing transcription factor ChREBP is targeted by proline hydroxylation
16. A long hypoxia-inducible factor 3 isoform 2 is a transcription activator that regulates erythropoietin
17. HIF-P4H-2 inhibition enhances intestinal fructose metabolism and induces thermogenesis protecting against NAFLD
18. Null mutation in P4h-tm leads to decreased fear and anxiety and increased social behavior in mice
19. Systemic inactivation of hypoxia-inducible factor prolyl 4-hydroxylase 2 in mice protects from alcohol-induced fatty liver disease
20. Interactions between lysyl oxidases and ADAMTS proteins suggest a novel crosstalk between two extracellular matrix families
21. Contribution of collagen XIII to lung function and development of pulmonary fibrosis
22. Collagen prolyl 4-hydroxylase isoenzymes I and II have sequence specificity towards different X-Pro-Gly triplets
23. Proline hydroxylation in collagen supports integrin binding by two distinct mechanisms
24. Premature Aggregation of Type IV Collagen and Early Lethality in Lysyl Hydroxylase 3 Null Mice
25. CD146+ cells are essential for kidney vasculature development
26. Severe Extracellular Matrix Abnormalities and Chondrodysplasia in Mice Lacking Collagen Prolyl 4-Hydroxylase Isoenzyme II in Combination with a Reduced Amount of Isoenzyme I
27. Kinetic Analysis of HIF Prolyl Hydroxylases
28. HIF-P4H-2 deficiency protects against skeletal muscle ischemia-reperfusion injury
29. Intracellular Post-Translational Modifications of Collagens
30. Molecular Biology and Biosynthesis of Collagens
31. The Structural Motifs for Substrate Binding and Dimerization of the α Subunit of Collagen Prolyl 4-Hydroxylase
32. Recombinant expression of human collagens
33. Prolyl 4-Hydroxlase Activity Is Essential for Development and Cuticle Formation in the Human Infective Parasitic Nematode Brugia malayi
34. PHD1 regulates p53‐mediated colorectal cancer chemoresistance
35. Hypoxia-inducible Factor-1 (HIF-1) but Not HIF-2 Is Essential for Hypoxic Induction of Collagen Prolyl 4-Hydroxylases in Primary Newborn Mouse Epiphyseal Growth Plate Chondrocytes
36. Transmembrane prolyl 4-hydroxylase is a fourth prolyl 4-hydroxylase regulating EPO production and erythropoiesis
37. Reduced Bone Mass in Collagen Prolyl 4‐Hydroxylase P4ha1 +/− ; P4ha2 −/− Compound Mutant Mice
38. Collagen binding specificity of the discoidin domain receptors: Binding sites on collagens II and III and molecular determinants for collagen IV recognition by DDR1
39. Chlamydomonas reinhardtii Has Multiple Prolyl 40-Hydroxylases, One of Which Is Essential for Proper Cell Was Assembly
40. Extracellular Matrix and Developing Growth Plate
41. Collagen Hydroxylases
42. Deficiency of a Transmembrane Prolyl 4-Hydroxylase in the Zebrafish Leads to Basement Membrane Defects and Compromised Kidney Function
43. Hearts of Hypoxia-inducible Factor Prolyl 4-Hydroxylase-2 Hypomorphic Mice Show Protection against Acute Ischemia-Reperfusion Injury
44. Hypoxia-inducible factor (HIF)-3α is subject to extensive alternative splicing in human tissues and cancer cells and is regulated by HIF-1 but not HIF-2
45. Missense Mutations That Cause Bruck Syndrome Affect Enzymatic Activity, Folding, and Oligomerization of Lysyl Hydroxylase 2
46. The Crystal Structure of an Algal Prolyl 4-Hydroxylase Complexed with a Proline-rich Peptide Reveals a Novel Buried Tripeptide Binding Motif
47. T-Cell Activation Leads to Reduced Collagen Maturation in Atherosclerotic Plaques of Apoe−/− Mice
48. Roles of the human hypoxia-inducible factor (HIF)-3α variants in the hypoxia response
49. Lysyl Oxidase Oxidizes Cell Membrane Proteins and Enhances the Chemotactic Response of Vascular Smooth Muscle Cells
50. Characterization of Recombinant Human Prolyl 3-Hydroxylase Isoenzyme 2, an Enzyme Modifying the Basement Membrane Collagen IV
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