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16 results on '"Mylrea-Foley, Bronacha"'

1. Do differences in diagnostic criteria for late fetal growth restriction matter?

Author

Arabin, B., Berger, A., Bergman, E., Bhide, A., Bilardo, C.M., Breeze, A.C., Brodszki, J., Calda, P., Cesari, E., Cetin, I., Derks, J., Ebbing, C., Ferrazzi, E., Frusca, T., Ganzevoort, W., Gyselaers, W., Hecher, K., Klaritsch, P., Krofta, L., Lindgren, P., Lobmaier, S.M., Marlow, N, Maruotti, G.M., Mecacci, F., Myklestad, K., Prefumo, F., Raio, L., Richter, J., Sande, R.K., Valensise, H., Visser, G.H.A., Wee, L., Mylrea-Foley, Bronacha, Napolitano, Raffaele, Gordijn, Sanne, Wolf, Hans, Lees, Christoph C., and Stampalija, Tamara

Published
2023
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2. Reduced fetal growth velocity and weight loss are associated with adverse perinatal outcome in fetuses at risk of growth restriction

Author

Arabin, Bine, Berger, Astrid, Bergman, Eva, Bhide, Amarnath, Bilardo, Caterina M., Breeze, Andrew C., Brodszki, Jana, Calda, Pavel, Cesari, Elena, Cetin, Irene, Derks, Jan B., Ebbing, Catherine, Ferrazzi, Enrico, Frusca, Tiziana, Ganzevoort, Wessel, Gordijn, Sanne J., Gyselaers, Wilfried, Hecher, Kurt, Klaritsch, Philipp, Krofta, Ladislav, Lindgren, Peter, Lobmaier, Silvia M., Maruotti, Gisuseppe M., Mecacci, Federico, Myklestad, Kirsti, Napolitano, Rafaele., Prefumo, Federico, Raio, Luigi, Richter, Jute, Sande, Ragnar K., Thornton, Jim, Valensise, Herbert, Visser, Gerry H.A., Wee, Ling, Stampalija, Tamara, Wolf, Hans, Mylrea-Foley, Bronacha, Marlow, Neil, Stephens, Katie J., Shaw, Caroline J., and Lees, Christoph C.

Published
2023
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3. Do differences in diagnostic criteria for late fetal growth restriction matter?

Author

Mylrea-Foley, Bronacha, primary, Napolitano, Raffaele, additional, Gordijn, Sanne, additional, Wolf, Hans, additional, Lees, Christoph C., additional, Stampalija, Tamara, additional, Arabin, B., additional, Berger, A., additional, Bergman, E., additional, Bhide, A., additional, Bilardo, C.M., additional, Breeze, A.C., additional, Brodszki, J., additional, Calda, P., additional, Cesari, E., additional, Cetin, I., additional, Derks, J., additional, Ebbing, C., additional, Ferrazzi, E., additional, Frusca, T., additional, Ganzevoort, W., additional, Gyselaers, W., additional, Hecher, K., additional, Klaritsch, P., additional, Krofta, L., additional, Lindgren, P., additional, Lobmaier, S.M., additional, Marlow, N, additional, Maruotti, G.M., additional, Mecacci, F., additional, Myklestad, K., additional, Prefumo, F., additional, Raio, L., additional, Richter, J., additional, Sande, R.K., additional, Valensise, H., additional, Visser, G.H.A., additional, and Wee, L., additional

Published
2023
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4. All FGR definitions fall short

Author

MYLREA-FOLEY, Bronacha, primary, NAPOLITANO, Raffaele, additional, GORDIJN, Sanne, additional, WOLF, Hans, additional, STAMPALIJA, Tamara, additional, and LEES, Christoph C, additional

Published
2023
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6. Reduced fetal growth velocity and weight loss are associated with adverse perinatal outcome in fetuses at risk of growth restriction

Author

Stampalija, Tamara, primary, Wolf, Hans, additional, Mylrea-Foley, Bronacha, additional, Marlow, Neil, additional, Stephens, Katie J., additional, Shaw, Caroline J., additional, Lees, Christoph C., additional, Arabin, Bine, additional, Berger, Astrid, additional, Bergman, Eva, additional, Bhide, Amarnath, additional, Bilardo, Caterina M., additional, Breeze, Andrew C., additional, Brodszki, Jana, additional, Calda, Pavel, additional, Cesari, Elena, additional, Cetin, Irene, additional, Derks, Jan B., additional, Ebbing, Catherine, additional, Ferrazzi, Enrico, additional, Frusca, Tiziana, additional, Ganzevoort, Wessel, additional, Gordijn, Sanne J., additional, Gyselaers, Wilfried, additional, Hecher, Kurt, additional, Klaritsch, Philipp, additional, Krofta, Ladislav, additional, Lindgren, Peter, additional, Lobmaier, Silvia M., additional, Maruotti, Gisuseppe M., additional, Mecacci, Federico, additional, Myklestad, Kirsti, additional, Napolitano, Rafaele., additional, Prefumo, Federico, additional, Raio, Luigi, additional, Richter, Jute, additional, Sande, Ragnar K., additional, Thornton, Jim, additional, Valensise, Herbert, additional, Visser, Gerry H.A., additional, and Wee, Ling, additional

Published
2023
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9. Perinatal and 2-year neurodevelopmental outcome in late preterm fetal compromise : the TRUFFLE 2 randomised trial protocol

Author

Mylrea-Foley, Bronacha, Thornton, Jim G., Mullins, Edward, Marlow, Neil, Hecher, Kurt, Ammari, Christina, Arabin, Birgit, Berger, Astrid, Bergman, Eva, Bhide, Amarnath, Bilardo, Caterina, Binder, Julia, Breeze, Andrew, Brodszki, Jana, Calda, Pavel, Cannings-John, Rebecca, Cerny, Andrej, Cesari, Elena, Cetin, Irene, Dall'Asta, Andrea, Diemert, Anke, Ebbing, Cathrine, Eggebø, Torbjørn, Fantasia, Ilaria, Ferrazzi, Enrico, Frusca, Tiziana, Ghi, Tullio, Goodier, Jenny, Greimel, Patrick, Gyselaers, Wilfried, Hassan, Wassim, Von Kaisenberg, Constantin, Kholin, Alexey, Klaritsch, Philipp, Krofta, Ladislav, Lindgren, Peter, Lobmaier, Silvia, Marsal, Karel, Maruotti, Giuseppe M., Mecacci, Federico, Myklestad, Kirsti, Napolitano, Raffaele, Ostermayer, Eva, Papageorghiou, Aris, Potter, Claire, Prefumo, Federico, Raio, Luigi, Richter, Jute, Sande, Ragnar Kvie, Schlembach, Dietmar, Schleussner, Ekkehard, Stampalija, Tamara, Thilaganathan, Basky, Townson, Julia, Valensise, Herbert, Ha Visser, Gerard, Wee, Ling, Wolf, Hans, Lees, Christoph C., Mylrea-Foley, Bronacha, Thornton, Jim G., Mullins, Edward, Marlow, Neil, Hecher, Kurt, Ammari, Christina, Arabin, Birgit, Berger, Astrid, Bergman, Eva, Bhide, Amarnath, Bilardo, Caterina, Binder, Julia, Breeze, Andrew, Brodszki, Jana, Calda, Pavel, Cannings-John, Rebecca, Cerny, Andrej, Cesari, Elena, Cetin, Irene, Dall'Asta, Andrea, Diemert, Anke, Ebbing, Cathrine, Eggebø, Torbjørn, Fantasia, Ilaria, Ferrazzi, Enrico, Frusca, Tiziana, Ghi, Tullio, Goodier, Jenny, Greimel, Patrick, Gyselaers, Wilfried, Hassan, Wassim, Von Kaisenberg, Constantin, Kholin, Alexey, Klaritsch, Philipp, Krofta, Ladislav, Lindgren, Peter, Lobmaier, Silvia, Marsal, Karel, Maruotti, Giuseppe M., Mecacci, Federico, Myklestad, Kirsti, Napolitano, Raffaele, Ostermayer, Eva, Papageorghiou, Aris, Potter, Claire, Prefumo, Federico, Raio, Luigi, Richter, Jute, Sande, Ragnar Kvie, Schlembach, Dietmar, Schleussner, Ekkehard, Stampalija, Tamara, Thilaganathan, Basky, Townson, Julia, Valensise, Herbert, Ha Visser, Gerard, Wee, Ling, Wolf, Hans, and Lees, Christoph C.

Abstract

Introduction: Following the detection of fetal growth restriction, there is no consensus about the criteria that should trigger delivery in the late preterm period. The consequences of inappropriate early or late delivery are potentially important yet practice varies widely around the world, with abnormal findings from fetal heart rate monitoring invariably leading to delivery. Indices derived from fetal cerebral Doppler examination may guide such decisions although there are few studies in this area. We propose a randomised, controlled trial to establish the optimum method of timing delivery between 32 weeks and 36 weeks 6 days of gestation. We hypothesise that delivery on evidence of cerebral blood flow redistribution reduces a composite of perinatal poor outcome, death and short-term hypoxia-related morbidity, with no worsening of neurodevelopmental outcome at 2 years. Methods and analysis: Women with non-anomalous singleton pregnancies 32+0 to 36+6 weeks of gestation in whom the estimated fetal weight or abdominal circumference is <10th percentile or has decreased by 50 percentiles since 18-32 weeks will be included for observational data collection. Participants will be randomised if cerebral blood flow redistribution is identified, based on umbilical to middle cerebral artery pulsatility index ratio values. Computerised cardiotocography (cCTG) must show normal fetal heart rate short term variation (>= 4.5 msec) and absence of decelerations at randomisation. Randomisation will be 1:1 to immediate delivery or delayed delivery (based on cCTG abnormalities or other worsening fetal condition). The primary outcome is poor condition at birth and/or fetal or neonatal death and/or major neonatal morbidity, the secondary non-inferiority outcome is 2-year infant general health and neurodevelopmental outcome based on the Parent Report of Children's Abilities-Revised questionnaire. Ethics and dissemination: The Study Coordination Centre has obtained approval from Lon

Published
2022
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10. Perinatal and 2-year neurodevelopmental outcome in late preterm fetal compromise: the TRUFFLE 2 randomised trial protocol

Author

Mylrea-Foley, Bronacha, primary, Thornton, Jim G, additional, Mullins, Edward, additional, Marlow, Neil, additional, Hecher, Kurt, additional, Ammari, Christina, additional, Arabin, Birgit, additional, Berger, Astrid, additional, Bergman, Eva, additional, Bhide, Amarnath, additional, Bilardo, Caterina, additional, Binder, Julia, additional, Breeze, Andrew, additional, Brodszki, Jana, additional, Calda, Pavel, additional, Cannings-John, Rebecca, additional, Černý, Andrej, additional, Cesari, Elena, additional, Cetin, Irene, additional, Dall'Asta, Andrea, additional, Diemert, Anke, additional, Ebbing, Cathrine, additional, Eggebø, Torbjørn, additional, Fantasia, Ilaria, additional, Ferrazzi, Enrico, additional, Frusca, Tiziana, additional, Ghi, Tullio, additional, Goodier, Jenny, additional, Greimel, Patrick, additional, Gyselaers, Wilfried, additional, Hassan, Wassim, additional, Von Kaisenberg, Constantin, additional, Kholin, Alexey, additional, Klaritsch, Philipp, additional, Krofta, Ladislav, additional, Lindgren, Peter, additional, Lobmaier, Silvia, additional, Marsal, Karel, additional, Maruotti, Giuseppe M, additional, Mecacci, Federico, additional, Myklestad, Kirsti, additional, Napolitano, Raffaele, additional, Ostermayer, Eva, additional, Papageorghiou, Aris, additional, Potter, Claire, additional, Prefumo, Federico, additional, Raio, Luigi, additional, Richter, Jute, additional, Sande, Ragnar Kvie, additional, Schlembach, Dietmar, additional, Schleußner, Ekkehard, additional, Stampalija, Tamara, additional, Thilaganathan, Basky, additional, Townson, Julia, additional, Valensise, Herbert, additional, Visser, Gerard HA, additional, Wee, Ling, additional, Wolf, Hans, additional, and Lees, Christoph C, additional

Published
2022
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14. Reduced fetal growth velocity and weight loss are associated with adverse perinatal outcome in fetuses at risk of growth restriction

Author

Tamara Stampalija, Hans Wolf, Bronacha Mylrea-Foley, Neil Marlow, Katie J. Stephens, Caroline J. Shaw, Christoph C. Lees, Bine Arabin, Astrid Berger, Eva Bergman, Amarnath Bhide, Caterina M. Bilardo, Andrew C. Breeze, Jana Brodszki, Pavel Calda, Elena Cesari, Irene Cetin, Jan B. Derks, Catherine Ebbing, Enrico Ferrazzi, Tiziana Frusca, Wessel Ganzevoort, Sanne J. Gordijn, Wilfried Gyselaers, Kurt Hecher, Philipp Klaritsch, Ladislav Krofta, Peter Lindgren, Silvia M. Lobmaier, Gisuseppe M. Maruotti, Federico Mecacci, Kirsti Myklestad, Rafaele. Napolitano, Federico Prefumo, Luigi Raio, Jute Richter, Ragnar K. Sande, Jim Thornton, Herbert Valensise, Gerry H.A. Visser, Ling Wee, Stampalija, Tamara, Wolf, Han, Mylrea-Foley, Bronacha, Marlow, Neil, Stephens, Katie J, Shaw, Caroline J, Lees, Christoph C, VU University medical center, Obstetrics and Gynaecology, APH - Quality of Care, and Amsterdam Reproduction & Development (AR&D)

Subjects
Growth velocity, middle cerebral artery, hypoxemia, adverse outcome, cerebral blood flow redistribution, catabolism, Doppler, umbilical-cerebral ratio, Obstetrics and Gynecology, 610 Medicine & health, cerebro-placental ratio, brain sparing, fetal growth restriction, small for gestational age, growth velocity
Abstract

Background: Although fetal size is associated with adverse perinatal outcome, the relationship between fetal growth velocity and adverse perinatal outcome is unclear. Objective: This study aimed to evaluate the relationship between fetal growth velocity and signs of cerebral blood flow redistribution, and their association with birthweight and adverse perinatal outcome. Study Design: This study was a secondary analysis of the TRUFFLE-2 multicenter observational prospective feasibility study of fetuses at risk of fetal growth restriction between 32 +0 and 36 +6 weeks of gestation (n=856), evaluated by ultrasound biometry and umbilical and middle cerebral artery Doppler. Individual fetal growth velocity was calculated from the difference of birthweight and estimated fetal weight at 3, 2, and 1 week before delivery, and by linear regression of all available estimated fetal weight measurements. Fetal estimated weight and birthweight were expressed as absolute value and as multiple of the median for statistical calculation. The coefficients of the individual linear regression of estimated fetal weight measurements (growth velocity; g/wk) were plotted against the last umbilical-cerebral ratio with subclassification for perinatal outcome. The association of these measurements with adverse perinatal outcome was assessed. The adverse perinatal outcome was a composite of abnormal condition at birth or major neonatal morbidity. Results: Adverse perinatal outcome was more frequent among fetuses whose antenatal growth was

Published
2022
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15. Current practice in the diagnosis and management of fetal growth restriction: An international survey

Author

Ilaria Fantasia, Giulia Zamagni, Christoph Lees, Bronacha Mylrea‐Foley, Lorenzo Monasta, Edward Mullins, Federico Prefumo, Tamara Stampalija, Fantasia, Ilaria, Zamagni, Giulia, Lees, Christoph, Mylrea-Foley, Bronacha, Monasta, Lorenzo, Mullins, Edward, Prefumo, Federico, and Stampalija, Tamara

Subjects
fetal growth retardation, Gestational Age, Umbilical Arteries, Ultrasonography, Prenatal, 1117 Public Health and Health Services, Pregnancy, Surveys and Questionnaires, Humans, Obstetrics & Reproductive Medicine, OUTCOMES, middle cerebral artery, Science & Technology, Fetal Growth Retardation, Obstetrics and Gynecology, Obstetrics & Gynecology, Ultrasonography, Doppler, General Medicine, fetal Doppler, surveys and questionnaires, 1114 Paediatrics and Reproductive Medicine, Female, cardiotocography, Life Sciences & Biomedicine, Biomarkers, TRUFFLE
Abstract

INTRODUCTION: The aim of this survey was to evaluate the current practice in respect of diagnosis and management of fetal growth restriction among obstetricians in different countries. MATERIAL AND METHODS: An e-questionnaire was sent via REDCap with "click thru" links in emails and newsletters to obstetric practitioners in different countries and settings with different levels of expertise. Clinical scenarios in early and late fetal growth restriction were given, followed by structured questions/response pairings. RESULTS: A total of 275 participants replied to the survey with 87% of responses complete. Participants were obstetrician/gynecologists (54%; 148/275) and fetal medicine specialists (43%; 117/275), and the majority practiced in a tertiary teaching hospital (56%; 153/275). Delphi consensus criteria for fetal growth restriction diagnosis were used by 81% of participants (223/275) and 82% (225/274) included a drop in fetal growth velocity in their diagnostic criteria for late fetal growth restriction. For early fetal growth restriction, TRUFFLE criteria were used for fetal monitoring and delivery timing by 81% (223/275). For late fetal growth restriction, indices of cerebral blood flow redistribution were used by 99% (250/252), most commonly cerebroplacental ratio (54%, 134/250). Delivery timing was informed by cerebral blood flow redistribution in 72% (176/244), used from ≥32 weeks of gestation. Maternal biomarkers and hemodynamics, as additional tools in the context of early-onset fetal growth restriction (≤32 weeks of gestation), were used by 22% (51/232) and 46% (106/230), respectively. CONCLUSIONS: The diagnosis and management of fetal growth restriction are fairly homogeneous among different countries and levels of practice, particularly for early fetal growth restriction. Indices of cerebral flow distribution are widely used in the diagnosis and management of late fetal growth restriction, whereas maternal biomarkers and hemodynamics are less frequently assessed but more so in early rather than late fetal growth restriction. Further standardization is needed for the definition of cerebral blood flow redistribution. ispartof: ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA vol:101 issue:12 pages:1431-1439 ispartof: location:United States status: published

Published
2022

16. Longitudinal Doppler Assessments in Late Preterm Fetal Growth Restriction.

Author

Mylrea-Foley B, Wolf H, Stampalija T, Lees C, Arabin B, Berger A, Bergman E, Bhide A, Bilardo CM, Breeze AC, Brodszki J, Calda P, Cetin I, Cesari E, Derks J, Ebbing C, Ferrazzi E, Ganzevoort W, Frusca T, Gordijn SJ, Gyselaers W, Hecher K, Klaritsch P, Krofta L, Lindgren P, Lobmaier SM, Marlow N, Maruotti GM, Mecacci F, Myklestad K, Napolitano R, Prefumo F, Raio L, Richter J, Sande RK, Thornton J, Valensise H, Visser GHA, and Wee L

Subjects
Pregnancy, Infant, Newborn, Female, Humans, Prospective Studies, Ultrasonography, Prenatal, Infant, Small for Gestational Age, Ultrasonography, Doppler, Fetal Weight, Gestational Age, Umbilical Arteries diagnostic imaging, Fetal Growth Retardation, Premature Birth
Abstract

Purpose:  To assess the longitudinal variation of the ratio of umbilical and cerebral artery pulsatility index (UCR) in late preterm fetal growth restriction (FGR)., Materials and Methods:  A prospective European multicenter observational study included women with a singleton pregnancy, 32 + 0 -36 + 6 , at risk of FGR (estimated fetal weight [EFW] or abdominal circumference [AC] < 10 th percentile, abnormal arterial Doppler or fall in AC from 20-week scan of > 40 percentile points). The primary outcome was a composite of abnormal condition at birth or major neonatal morbidity. UCR was categorized as normal (< 0.9) or abnormal (≥ 0.9). UCR was assessed by gestational age at measurement interval to delivery, and by individual linear regression coefficient in women with two or more measurements., Results:  856 women had 2770 measurements; 696 (81 %) had more than one measurement (median 3 (IQR 2-4). At inclusion, 63 (7 %) a UCR ≥ 0.9. These delivered earlier and had a lower birth weight and higher incidence of adverse outcome (30 % vs. 9 %, relative risk 3.2; 95 %CI 2.1-5.0) than women with a normal UCR at inclusion. Repeated measurements after an abnormal UCR at inclusion were abnormal again in 67 % (95 %CI 55-80), but after a normal UCR the chance of finding an abnormal UCR was 6 % (95 %CI 5-7 %). The risk of composite adverse outcome was similar using the first or subsequent UCR values., Conclusion:  An abnormal UCR is likely to be abnormal again at a later measurement, while after a normal UCR the chance of an abnormal UCR is 5-7 % when repeated weekly. Repeated measurements do not predict outcome better than the first measurement, most likely due to the most compromised fetuses being delivered after an abnormal UCR., Competing Interests: The authors declare that they have no conflict of interest., (Thieme. All rights reserved.)

Published
2023
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