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1. Transcriptomic and epigenetic responses shed light on soybean resistance to Phytophthora sansomeana

Author

Gwonjin Lee, Charlotte N. DiBiase, Beibei Liu, Tong Li, Austin G. McCoy, Martin I. Chilvers, Lianjun Sun, Dechun Wang, Feng Lin, and Meixia Zhao

Subjects
Plant culture, SB1-1110, Genetics, QH426-470
Abstract

Abstract Phytophthora root rot, caused by oomycete pathogens in the Phytophthora genus, poses a significant threat to soybean productivity. While resistance mechanisms against Phytophthora sojae have been extensively studied in soybean, the molecular basis underlying immune responses to Phytophthora sansomeana remains unclear. In this study, we investigated transcriptomic and epigenetic responses of two resistant (Colfax and NE2701) and two susceptible (Williams 82 and Senaki) soybean lines at four time points (2, 4, 8, and 16 h post inoculation [hpi]) after P. sansomeana inoculation. Comparative transcriptomic analyses revealed a greater number of differentially expressed genes (DEGs) upon pathogen inoculation in resistant lines, particularly at 8 and 16 hpi. These DEGs were predominantly associated with defense response, ethylene, and reactive oxygen species‐mediated defense pathways. Moreover, DE transposons were predominantly upregulated after inoculation, and more of them were enriched near genes in Colfax than other soybean lines. Notably, we identified a long non‐coding RNA (lncRNA) within the mapped region of the resistance gene that exhibited exclusive upregulation in the resistant lines after inoculation, potentially regulating two flanking LURP‐one‐related genes. Furthermore, DNA methylation analysis revealed increased CHH (where H = A, T, or C) methylation levels in lncRNAs after inoculation, with delayed responses in Colfax compared to Williams 82. Overall, our results provide comprehensive insights into soybean responses to P. sansomeana, highlighting potential roles of lncRNAs and epigenetic regulation in plant defense.

Published
2024
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2. HaloTag display enables quantitative single‐particle characterisation and functionalisation of engineered extracellular vesicles

Author

Roxana E. Mitrut, Devin M. Stranford, Beth N. DiBiase, Jonathan M. Chan, Matthew D. Bailey, Minrui Luo, Clare S. Harper, Thomas J. Meade, Muzhou Wang, and Joshua N. Leonard

Subjects
extracellular vesicle, HaloTag, quantification, single vesicle, Cytology, QH573-671
Abstract

Abstract Extracellular vesicles (EVs) play key roles in diverse biological processes, transport biomolecules between cells and have been engineered for therapeutic applications. A useful EV bioengineering strategy is to express engineered proteins on the EV surface to confer targeting, bioactivity and other properties. Measuring how incorporation varies across a population of EVs is important for characterising such materials and understanding their function, yet it remains challenging to quantitatively characterise the absolute number of engineered proteins incorporated at single‐EV resolution. To address these needs, we developed a HaloTag‐based characterisation platform in which dyes or other synthetic species can be covalently and stoichiometrically attached to engineered proteins on the EV surface. To evaluate this system, we employed several orthogonal quantification methods, including flow cytometry and fluorescence microscopy, and found that HaloTag‐mediated quantification is generally robust across EV analysis methods. We compared HaloTag‐labelling to antibody‐labelling of EVs using single vesicle flow cytometry, enabling us to measure the substantial degree to which antibody labelling can underestimate proteins present on an EV. Finally, we demonstrate the use of HaloTag to compare between protein designs for EV bioengineering. Overall, the HaloTag system is a useful EV characterisation tool which complements and expands existing methods.

Published
2024
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3. Design and construction of the fast photon detection system for COMPASS RICH-1

Author

J. Polak, M. Alexeev, V.N. Kolosov, Christian Schill, M. L. Colantoni, L. Steiger, H. Wollny, P. Schoenmeier, G. Menon, S. Gerassimov, F. Kunne, D. Neyret, M. Slunečka, M. Svec, A. Mann, A. Mutter, N. Dibiase, A. Lehmann, V. Duic, P. Ciliberti, S. Levorato, D. Panzieri, V. Diaz, B. Ketzer, F. Robinet, K. Königsmann, R. Joosten, R. Hagemann, B. Gobbo, M. Finger, W. Schröder, Eric Delagnes, M. Chiosso, Andrea Ferrero, F. Nerling, S. Dalla Torre, T. Dafni, R. Birsa, A. Maggiora, A. Teufel, Anne-Laure Martin, Laura Silva, F. Tessarotto, Daniel B. Kramer, P. Bordalo, F. Sozzi, P. Rebourgeard, S. Takekawa, H. Deschamps, H. Fischer, Soumen Paul, Ph. Abbon, O. Nähle, Andrea Bressan, C. Pizzolotto, I. Konorov, F.H. Heinsius, Miroslav Sulc, A. Magnon, M. Giorgi, O. Y. Denisov, W. Eyrich, D. von Harrach, G. Pesaro, Elena Rocco, Franco Bradamante, P. Schiavon, H. Angerer, Département d'Electronique, des Détecteurs et d'Informatique pour la Physique (ex SEDI) (DEDIP), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Département de Physique Nucléaire (ex SPhN) (DPHN), COMPASS, P., Abbon, M., Alexeev, H., Angerer, R., Birsa, P., Bordalo, Bradamante, Franco, Bressan, Andrea, M., Chiosso, Ciliberti, Piero, M., Colantoni, T., Dafni, S., Dallatorre, E., Delagne, O., Denisov, H., Deschamp, V., Diaz, N., Dibiase, Duic, Venicio, W., Eyrich, A., Ferrero, M., Finger, M., Fingerjr, H., Fischer, S., Gerassimov, Giorgi, Marcello, B., Gobbo, R., Hagemann, D., Vonharrach, F. H., Heinsiu, R., Joosten, B., Ketzer, V. N., Kolosov, K., Koenigsmann, I., Konorov, D., Kramer, F., Kunne, A., Lehmann, Levorato, Stefano, A., Maggiora, A., Magnon, A., Mann, Martin, Anna, G., Menon, A., Mutter, O., Naehle, F., Nerling, D., Neyret, D., Panzieri, S., Paul, Pesaro, Giulia, C., Pizzolotto, J., Polak, P., Rebourgeard, F., Robinet, E., Rocco, Schiavon, Paolo, C., Schill, P., Schoenmeier, W., Schroeder, L., Silva, M., Slunecka, Sozzi, Federica, L., Steiger, M., Sulc, M., Svec, Takekawa, Stefano, F., Tessarotto, A., Teufel, and H., Wollny

Subjects
Nuclear and High Energy Physics, Photomultiplier, Physics::Instrumentation and Detectors, Multi-anode photo-multiplier, [PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex], COMPASS, 01 natural sciences, Particle identification, law.invention, Optics, RICH, Quartz lens telescope, law, Compass, 0103 physical sciences, COMPASS experiment, Angular resolution, Electronics, 010306 general physics, Instrumentation, Cherenkov radiation, Physics, Large Hadron Collider, 010308 nuclear & particles physics, business.industry, Lens (optics), High Energy Physics::Experiment, business
Abstract

International audience; New photon detectors, based on the use of multi-anode photo-multiplier tubes coupled to individual lens telescopes and read out with a dedicated read-out electronics system, equip the central region of the Cherenkov imaging counter RICH-1 of the COMPASS experiment at CERN SPS. They are characterised by high photon yield, fast response and high rate capability and are successfully in operation since the 2006 COMPASS data taking. The photon detection system fully matches the expected performance. The design and construction of the photon detectors are described in detail.

Published
2010
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4. The COMPASS RICH-1 fast photon detection system

Author

P. Abbon, M. Alexeev, H. Angerer, R. Birsa, P. Bordalo, F. Bradamante, A. Bressan, M. Chiosso, P. Ciliberti, M.L. Colantoni, T. Dafni, S. Dalla Torre, E. Delagnes, O. Denisov, H. Deschamps, V. Diaz, N. Dibiase, V. Duic, W. Eyrich, A. Ferrero, M. Finger, M. Finger Jr., H. Fischer, S. Gerassimov, M. Giorgi, B. Gobbo, R. Hagemann, D. von Harrach, F.H. Heinsius, R. Joosten, B. Ketzer, V.N. Kolosov, K. Königsmann, I. Konorov, D. Kramer, F. Kunne, A. Lehmann, S. Levorato, A. Maggiora, A. Magnon, A. Mann, A. Martin, G. Menon, A. Mutter, O. Nähle, F. Nerling, D. Neyret, D. Panzieri, S. Paul, G. Pesaro, C. Pizzolotto, J. Polak, P. Rebourgeard, F. Robinet, E. Rocco, P. Schiavon, C. Schill, P. Schoenmeier, W. Schröder, L. Silva, M. Slunecka, F. Sozzi, L. Steiger, M. Sulc, M. Svec, S. Takekawa, F. Tessarotto, A. Teufel, H. Wollny, Abbon, P, Alexeev, M, Angerer, H, Birsa, R, Bordalo, P, Bradamante, F, Bressan, Andrea, Chiosso, M, Ciliberti, Piero, COLANTONI M., L, Dafni, T, DALLA TORRE, S, Delagnes, E, Denisov, O, Deschamps, H, Diaz, V, Dibiase, N, Duic, V, Eyrich, W, Ferrero, A, Finger, M, FINGER M., Jr, Fischer, H, Gerassimov, S, Giorgi, M, Gobbo, B, Hagemann, R, VON HARRACH, D, HEINSIUS F., H, Joosten, R, Ketzer, B, KOLOSOV V., N, Königsmann, K, Konorov, I, Kramer, D, Kunne, F, Lehmann, A, Levorato, Stefano, Maggiora, A, Magnon, A, Mann, A, Martin, Anna, Menon, G, Mutter, A, Nähle, O, Nerling, F, Neyret, D, Panzieri, D, Paul, S, Pesaro, G, Pizzolotto, C, Polak, J, Rebourgeard, P, Robinet, F, Rocco, E, Schiavon, Paolo, Schill, C, Schoenmeier, P, Schröder, W, Silva, L, Slunecka, M, Sozzi, F, Steiger, L, Sulc, M, Svec, M, Takekawa, Stefano, Tessarotto, F, Teufel, A, and Wollny, H.

Subjects
Physics, Nuclear and High Energy Physics, Photomultiplier, Physics::Instrumentation and Detectors, business.industry, Photon detector, Detector, law.invention, Lens (optics), Optics, Upgrade, law, Compass, Systems design, Optoelectronics, High Energy Physics::Experiment, business, Instrumentation, Photon detection
Abstract

A fast photon detection system has been built as a part of the upgrade of the COMPASS RICH-1 detector: it is based on 576 multi-anode photomultiplier tubes (MAPMTs) coupled to individual fused silica lens telescopes and fast readout electronics. This system has replaced the MWPCs with CsI photo-cathodes in the central region ( 1.3 m 2 , 25% of the total area) of the COMPASS RICH-1 photon detectors and has successfully been operated during the data taking in 2006 and 2007. We report about the fast photon detection system design, construction and commissioning, in particular about the design optimization and the validation tests of the lens telescopes. Preliminary values for the increased performances of COMPASS RICH-1 after the upgrade are also presented.

Published
2008
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5. The fast readout system for the MAPMTs of COMPASS RICH-1

Author

P. Abbon, M. Alexeev, H. Angerer, R. Birsa, P. Bordalo, F. Bradamante, A. Bressan, M. Chiosso, P. Ciliberti, M.L. Colantoni, T. Dafni, S. Dalla Torre, E. Delagnes, O. Denisov, H. Deschamps, V. Diaz, N. Dibiase, V. Duic, W. Eyrich, A. Ferrero, M. Finger, H. Fischer, S. Gerassimov, M. Giorgi, B. Gobbo, R. Hagemann, D. von Harrach, F.H. Heinsius, R. Joosten, B. Ketzer, V.N. Kolosov, K. Königsmann, I. Konorov, D. Kramer, F. Kunne, A. Lehmann, S. Levorato, A. Maggiora, A. Magnon, A. Mann, A. Martin, G. Menon, A. Mutter, O. Nähle, F. Nerling, D. Neyret, D. Panzieri, S. Paul, G. Pesaro, C. Pizzolotto, J. Polak, P. Rebourgeard, F. Robinet, E. Rocco, P. Schiavon, C. Schill, P. Schoenmeier, W. Schröder, L. Silva, M. Slunecka, F. Sozzi, L. Steiger, M. Sulc, M. Svec, S. Takekawa, F. Tessarotto, A. Teufel, H. Wollny, Abbon, P, Alexeev, M, Angerer, H, Birsa, R, Bordalo, P, Bradamante, Franco, Bressan, Andrea, Chiosso, M, Ciliberti, Piero, COLANTONI M., L, Dafni, T, DALLA TORRE, S, Delagnes, E, Denisov, O, Deschamps, H, Diaz, V, Dibiase, N, Duic, V, Eyrich, W, Ferrero, A, Finger, M, FINGER M., Jr, Fischer, H, Gerassimov, S, Giorgi, M, Gobbo, B, Hagemann, R, VON HARRACH, D, HEINSIUS F., H, Joosten, R, Ketzer, B, KOLOSOV V., N, Königsmann, K, Konorov, I, Kramer, D, Kunne, F, Lehmann, A, Levorato, Stefano, Maggiora, A, Magnon, A, Mann, A, Martin, Anna, Menon, G, Mutter, A, Nähle, O, Nerling, F, Neyret, D, Panzieri, D, Paul, S, Pesaro, G, Pizzolotto, C, Polak, J, Rebourgeard, P, Robinet, F, Rocco, E, Schiavon, Paolo, Schill, C, Schoenmeier, P, Schröder, W, Silva, L, Slunecka, M, Sozzi, F, Steiger, L, Sulc, M, Svec, M, Takekawa, Stefano, Tessarotto, F, Teufel, A, and Wollny, H.

Subjects
Physics, Nuclear and High Energy Physics, Photomultiplier, Physics - Instrumentation and Detectors, Physics::Instrumentation and Detectors, business.industry, Detector, Photon flux, FOS: Physical sciences, Readout electronics, Instrumentation and Detectors (physics.ins-det), Chip, Particle identification, Upgrade, Optics, Compass, Detectors and Experimental Techniques, business, Instrumentation
Abstract

A fast readout system for the upgrade of the COMPASS RICH detector has been developed and successfully used for data taking in 2006 and 2007. The new readout system for the multi-anode PMTs in the central part of the photon detector of the RICH is based on the high-sensitivity MAD4 preamplifier-discriminator and the dead-time free F1-TDC chip characterized by high-resolution. The readout electronics has been designed taking into account the high photon flux in the central part of the detector and the requirement to run at high trigger rates of up to 100 kHz with negligible dead-time. The system is designed as a very compact setup and is mounted directly behind the multi-anode photomultipliers. The data are digitized on the frontend boards and transferred via optical links to the readout system. The read-out electronics system is described in detail together with its measured performances., Comment: Proceeding of RICH2007 Conference, Trieste, Oct. 2007. v2: minor changes

Published
2008
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6. The COMPASS experiment at CERN

Author

P. Abbon, E. Albrecht, V.Yu. Alexakhin, Yu. Alexandrov, G.D. Alexeev, M.G. Alekseev, A. Amoroso, H. Angerer, V.A. Anosov, B. Badełek, F. Balestra, J. Ball, J. Barth, G. Baum, M. Becker, Y. Bedfer, P. Berglund, C. Bernet, R. Bertini, M. Bettinelli, R. Birsa, J. Bisplinghoff, P. Bordalo, M. Bosteels, F. Bradamante, A. Braem, A. Bravar, A. Bressan, G. Brona, E. Burtin, M.P. Bussa, V.N. Bytchkov, M. Chalifour, A. Chapiro, M. Chiosso, P. Ciliberti, A. Cicuttin, M. Colantoni, A.A. Colavita, S. Costa, M.L. Crespo, P. Cristaudo, T. Dafni, N. d’Hose, S. Dalla Torre, C. d’Ambrosio, S. Das, S.S. Dasgupta, E. Delagnes, R. De Masi, P. Deck, N. Dedek, D. Demchenko, O.Yu. Denisov, L. Dhara, V. Diaz, N. Dibiase, A.M. Dinkelbach, A.V. Dolgopolov, A. Donati, S.V. Donskov, V.A. Dorofeev, N. Doshita, D. Durand, V. Duic, W. Dünnweber, A. Efremov, P.D. Eversheim, W. Eyrich, M. Faessler, V. Falaleev, P. Fauland, A. Ferrero, L. Ferrero, M. Finger, H. Fischer, C. Franco, J. Franz, F. Fratnik, J.M. Friedrich, V. Frolov, U. Fuchs, R. Garfagnini, L. Gatignon, F. Gautheron, O.P. Gavrichtchouk, S. Gerassimov, R. Geyer, J.M. Gheller, A. Giganon, M. Giorgi, B. Gobbo, S. Goertz, A.M. Gorin, F. Gougnaud, S. Grabmüller, O.A. Grajek, A. Grasso, B. Grube, A. Grünemaier, A. Guskov, F. Haas, R. Hagemann, J. Hannappel, D. von Harrach, T. Hasegawa, J. Heckmann, S. Hedicke, F.H. Heinsius, R. Hermann, C. Heß, F. Hinterberger, M. von Hodenberg, N. Horikawa, S. Horikawa, I. Horn, C. Ilgner, A.I. Ioukaev, S. Ishimoto, I. Ivanchin, O. Ivanov, T. Iwata, R. Jahn, A. Janata, R. Joosten, N.I. Jouravlev, E. Kabuß, V. Kalinnikov, D. Kang, F. Karstens, W. Kastaun, B. Ketzer, G.V. Khaustov, Yu.A. Khokhlov, J. Kiefer, Yu. Kisselev, F. Klein, K. Klimaszewski, S. Koblitz, J.H. Koivuniemi, V.N. Kolosov, E.V. Komissarov, K. Kondo, K. Königsmann, A.K. Konoplyannikov, I. Konorov, V.F. Konstantinov, A.S. Korentchenko, A. Korzenev, A.M. Kotzinian, N.A. Koutchinski, O. Kouznetsov, K. Kowalik, D. Kramer, N.P. Kravchuk, G.V. Krivokhizhin, Z.V. Kroumchtein, J. Kubart, R. Kuhn, V. Kukhtin, F. Kunne, K. Kurek, N.A. Kuzmin, M. Lamanna, J.M. Le Goff, M. Leberig, A.A. Lednev, A. Lehmann, V. Levinski, S. Levorato, V. I Lyashenko, J. Lichtenstadt, T. Liska, I. Ludwig, A. Maggiora, M. Maggiora, A. Magnon, G.K. Mallot, A. Mann, I.V. Manuilov, C. Marchand, J. Marroncle, A. Martin, J. Marzec, L. Masek, F. Massmann, T. Matsuda, D. Matthiä, A.N. Maximov, G. Menon, W. Meyer, A. Mielech, Yu.V. Mikhailov, M.A. Moinester, F. Molinié, F. Mota, A. Mutter, T. Nagel, O. Nähle, J. Nassalski, S. Neliba, F. Nerling, D. Neyret, M. Niebuhr, T. Niinikoski, V.I. Nikolaenko, A.A. Nozdrin, A.G. Olshevsky, M. Ostrick, A. Padee, P. Pagano, S. Panebianco, B. Parsamyan, D. Panzieri, S. Paul, B. Pawlukiewicz, H. Pereira, D.V. Peshekhonov, V.D. Peshekhonov, D. Piedigrossi, G. Piragino, S. Platchkov, K. Platzer, J. Pochodzalla, J. Polak, V.A. Polyakov, G. Pontecorvo, A.A. Popov, J. Pretz, S. Procureur, C. Quintans, J.-F. Rajotte, S. Ramos, I. Razaq, P. Rebourgeard, D. Reggiani, G. Reicherz, A. Richter, F. Robinet, E. Rocco, E. Rondio, L. Ropelewski, J.Y. Roussé, A.M. Rozhdestvensky, D. Ryabchikov, A.G. Samartsev, V.D. Samoylenko, A. Sandacz, M. Sans Merce, H. Santos, M.G. Sapozhnikov, F. Sauli, I.A. Savin, P. Schiavon, C. Schill, T. Schmidt, H. Schmitt, L. Schmitt, P. Schönmeier, W. Schroeder, D. Seeharsch, M. Seimetz, D. Setter, A. Shaligin, O.Yu. Shevchenko, A.A. Shishkin, H.-W. Siebert, L. Silva, F. Simon, L. Sinha, A.N. Sissakian, M. Slunecka, G.I. Smirnov, D. Sora, S. Sosio, F. Sozzi, A. Srnka, F. Stinzing, M. Stolarski, V.P. Sugonyaev, M. Sulc, R. Sulej, G. Tarte, N. Takabayashi, V.V. Tchalishev, S. Tessaro, F. Tessarotto, A. Teufel, D. Thers, L.G. Tkatchev, T. Toeda, V.V. Tokmenin, S. Trippel, J. Urban, R. Valbuena, G. Venugopal, M. Virius, N.V. Vlassov, A. Vossen, M. Wagner, R. Webb, E. Weise, Q. Weitzel, U. Wiedner, M. Wiesmann, R. Windmolders, S. Wirth, W. Wiślicki, H. Wollny, A.M. Zanetti, K. Zaremba, M. Zavertyaev, J. Zhao, R. Ziegler, M. Ziembicki, Y.L. Zlobin, A. Zvyagin, Abbon, P, Albrecht, E, ALEXAKHIN V., Yu, Alexandrov, Yu, ALEXEEV G., D, ALEKSEEV M., G, Amoroso, A, Angerer, H, ANOSOV V., A, Badelek, B, Balestra, F, Ball, J, Barth, J, Baum, G, Becker, M, Bedfer, Y, Berglund, P, Bernet, C, Bertini, R, Bettinelli, M, Birsa, R, Bisplinghoff, J, Bordalo, P, Bosteels, M, Bradamante, Franco, Braem, A, Bravar, A, Bressan, Andrea, Brona, G, Burtin, E, BUSSA M., P, BYTCHKOV V., N, Chalifour, M, Chapiro, A, Chiosso, M, Ciliberti, Piero, Cicuttin, A, Colantoni, M, COLAVITA A., A, Costa, S, CRESPO M., L, Cristaudo, P, Dafni, T, D'Hose, N, DALLA TORRE, S, D'Ambrosio, C, Das, S, DASGUPTA S., S, Delagnes, E, DE MASI, R, Deck, P, Dedek, N, Demchenko, D, DENISOV O., Yu, Dhara, L, Diaz, V, Dibiase, N, DINKELBACH A., M, DOLGOPOLOV A., V, Donati, A, DONSKOV S., V, DOROFEEV V., A, Doshita, N, Durand, D, Duic, V, Dünnweber, W, Efremov, A, EVERSHEIM P., D, Eyrich, W, Faessler, M, Falaleev, V, Fauland, P, Ferrero, A, Ferrero, L, Finger, M, FINGER M., Jr, Fischer, H, Franco, C, Franz, J, Fratnik, F, FRIEDRICH J., M, Frolov, V, Fuchs, U, Garfagnini, R, Gatignon, L, Gautheron, F, GAVRICHTCHOUK O., P, Gerassimov, S, Geyer, R, GHELLER J., M, Giganon, A, Giorgi, Marcello, Gobbo, B, Goertz, S, GORIN A., M, Gougnaud, F, Grabmüller, S, GRAJEK O., A, Grasso, A, Grube, B, Grünemaier, A, Guskov, A, Haas, F, Hagemann, R, Hannappel, J, VON HARRACH, D, Hasegawa, T, Heckmann, J, Hedicke, S, HEINSIUS F., H, Hermann, R, Hess, C, Hinterberger, F, VON HODENBERG, M, Horikawa, N, Horikawa, S, Horn, I, Ilgner, C, IOUKAEV A., I, Ishimoto, S, Ivanchin, I, Ivanov, O, Iwata, T, Jahn, R, Janata, A, Joosten, R, JOURAVLEV N., I, Kabuss, E, Kalinnikov, V, Kang, D, Karstens, F, Kastaun, W, Ketzer, B, KHAUSTOV G., V, KHOKHLOV Y. U., A, Kiefer, J, Kisselev, Yu, Klein, F, Klimaszewski, K, Koblitz, S, KOIVUNIEMI J., H, KOLOSOV V., N, KOMISSAROV E., V, Kondo, K, Königsmann, K, KONOPLYANNIKOV A., K, Konorov, I, KONSTANTINOV V., F, KORENTCHENKO A., S, Korzenev, A, KOTZINIAN A., M, KOUTCHINSKI N., A, Kouznetsov, O, Kowalik, K, Kramer, D, KRAVCHUK N., P, KRIVOKHIZHIN G., V, KROUMCHTEIN Z., V, Kubart, J, Kuhn, R, Kukhtin, V, Kunne, F, Kurek, K, KUZMIN N., A, Lamanna, M, LE GOFF J., M, Leberig, M, LEDNEV A., A, Lehmann, A, Levinski, V, Levorato, Stefano, I., LYASHENKO V, Lichtenstadt, J, Liska, T, Ludwig, I, Maggiora, A, Maggiora, M, Magnon, A, MALLOT G., K, Mann, A, MANUILOV I., V, Marchand, C, Marroncle, J, Martin, Anna, Marzec, J, Masek, L, Massmann, F, Matsuda, T, Matthiä, D, MAXIMOV A., N, Menon, G, Meyer, W, Mielech, A, MIKHAILOV Y. U., V, MOINESTER M., A, Molinié, F, Mota, F, Mutter, A, Nagel, T, Nähle, O, Nassalski, J, Neliba, S, Nerling, F, Neyret, D, Niebuhr, M, Niinikoski, T, NIKOLAENKO V., I, NOZDRIN A., A, OLSHEVSKY A., G, Ostrick, M, Padee, A, Pagano, P, Panebianco, S, Parsamyan, B, Panzieri, D, Paul, S, Pawlukiewicz, B, Pereira, H, PESHEKHONOV D., V, PESHEKHONOV V., D, Piedigrossi, D, Piragino, G, Platchkov, S, Platzer, K, Pochodzalla, J, Polak, J, POLYAKOV V., A, Pontecorvo, G, POPOV A., A, Pretz, J, Procureur, S, Quintans, C, RAJOTTE J., F, Ramos, S, Razaq, I, Rebourgeard, P, Reggiani, D, Reicherz, G, Richter, A, Robinet, F, Rocco, E, Rondio, E, Ropelewski, L, ROUSSÉ J., Y, ROZHDESTVENSKY A., M, Ryabchikov, D, SAMARTSEV A., G, SAMOYLENKO V., D, Sandacz, A, SANS MERCE, M, Santos, H, SAPOZHNIKOV M., G, Sauli, F, SAVIN I., A, Schiavon, Paolo, Schill, C, Schmidt, T, Schmitt, H, Schmitt, L, Schönmeier, P, Schroeder, W, Seeharsch, D, Seimetz, M, Setter, D, Shaligin, A, SHEVCHENKO O., Yu, SHISHKIN A., A, SIEBERT H., W, Silva, L, Simon, F, Sinha, L, SISSAKIAN A., N, Slunecka, M, SMIRNOV G., I, Sora, D, Sosio, S, Sozzi, F, Srnka, A, Stinzing, F, Stolarski, M, SUGONYAEV V., P, Sulc, M, Sulej, R, Tarte, G, Takabayashi, N, TCHALISHEV V., V, Tessaro, S, Tessarotto, F, Teufel, A, Thers, D, TKATCHEV L., G, Toeda, T, TOKMENIN V., V, Trippel, S, Urban, J, Valbuena, R, Venugopal, G, Virius, M, VLASSOV N., V, Vossen, A, Wagner, M, Webb, R, Weise, E, Weitzel, Q, Wiedner, U, Wiesmann, M, Windmolders, R, Wirth, S, Wisblicki, W, Wollny, H, ZANETTI A., M, Zaremba, K, Zavertyaev, M, Zhao, J, Ziegler, R, Ziembicki, M, ZLOBIN Y., L, and Zvyagin, A.

Subjects
Nuclear and High Energy Physics, straw tube detector, Physics::Instrumentation and Detectors, Project commissioning, FOS: Physical sciences, fixed-target experiment, RICH detector, hadron structure, High Energy Physics - Experiment, target, MWPC, Nuclear physics, High Energy Physics - Experiment (hep-ex), Compass, Hadron spectroscopy, COMPASS experiment, scintillating fibre detector, Nuclear Experiment, silicon microstrip detectors, Instrumentation, Silicon microstrip detectors, Physics, Large Hadron Collider, Structure function, MicroMegas detector, front-end electronics, DAQ, micromegas detector, drift chamber, Physics::Accelerator Physics, High Energy Physics::Experiment, polarised, GEM detector, calorimetry, Particle Physics - Experiment, polarised DIS
Abstract

The COMPASS experiment makes use of the CERN SPS high-intensitymuon and hadron beams for the investigation of the nucleon spin structure and the spectroscopy of hadrons. One or more outgoing particles are detected in coincidence with the incoming muon or hadron. A large polarized target inside a superconducting solenoid is used for the measurements with the muon beam. Outgoing particles are detected by a two-stage, large angle and large momentum range spectrometer. The setup is built using several types of tracking detectors, according to the expected incident rate, required space resolution and the solid angle to be covered. Particle identification is achieved using a RICH counter and both hadron and electromagnetic calorimeters. The setup has been successfully operated from 2002 onwards using a muon beam. Data with a hadron beam were also collected in 2004. This article describes the main features and performances of the spectrometer in 2004; a short summary of the 2006 upgrade is also given., 84 papes, 74 figures

Published
2007
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7. Particle identification with COMPASS RICH-1

Author

P. Abbon, M. Alexeev, H. Angerer, G. Baum, R. Birsa, P. Bordalo, F. Bradamante, A. Bressan, M. Chiosso, P. Ciliberti, M. Colantoni, T. Dafni, S. Dalla Torre, E. Delagnes, O. Denisov, H. Deschamps, N. Dibiase, V. Duic, W. Eyrich, A. Ferrero, M. Finger, H. Fischer, C. Franco, S. Gerassimov, M. Giorgi, B. Gobbo, R. Hagemann, D. von Harrach, F.H. Heinsius, R. Joosten, B. Ketzer, V.N. Kolosov, K. Königsmann, I. Konorov, D. Kramer, F. Kunne, A. Lehmann, S. Levorato, A. Maggiora, A. Magnon, A. Mann, A. Martin, G. Menon, A. Mutter, O. Nähle, F. Nerling, D. Neyret, D. Panzieri, S. Paul, G. Pesaro, C. Pizzolotto, J. Polak, P. Rebourgeard, F. Robinet, E. Rocco, G. Sbrizzai, P. Schiavon, C. Schill, P. Schoenmeier, W. Schröder, M. Slunecka, F. Sozzi, L. Steiger, M. Sulc, M. Svec, S. Takekawa, F. Tessarotto, A. Teufel, H. Wollny, Département d'Electronique, des Détecteurs et d'Informatique pour la Physique (ex SEDI) (DEDIP), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Département de Physique Nucléaire (ex SPhN) (DPHN), COMPASS, P., Abbon, M., Alexeev, H., Angerer, G., Baum, R., Birsa, P., Bordalo, Bradamante, Franco, Bressan, Andrea, M., Chiosso, Ciliberti, Piero, M., Colantoni, T., Dafni, S., Dallatorre, E., Delagne, O., Denisov, H., Deschamp, N., Dibiase, Duic, Venicio, W., Eyrich, A., Ferrero, M., Finger, M., Fingerjr, H., Fischer, C., Franco, S., Gerassimov, Giorgi, Marcello, B., Gobbo, R., Hagemann, D., Vonharrach, F. H., Heinsiu, R., Joosten, B., Ketzer, V. N., Kolosov, K., Koenigsmann, I., Konorov, D., Kramer, F., Kunne, A., Lehmann, Levorato, Stefano, A., Maggiora, A., Magnon, A., Mann, Martin, Anna, G., Menon, A., Mutter, O., Naehle, F., Nerling, D., Neyret, D., Panzieri, S., Paul, Pesaro, Giulia, C., Pizzolotto, J., Polak, P., Rebourgeard, F., Robinet, E., Rocco, Sbrizzai, Giulio, Schiavon, Paolo, C., Schill, P., Schoenmeier, W., Schroeder, M., Slunecka, Sozzi, Federica, L., Steiger, M., Sulc, M., Svec, Takekawa, Stefano, F., Tessarotto, A., Teufel, and H., Wollny

Subjects
Nuclear and High Energy Physics, Physics::Instrumentation and Detectors, [PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex], 01 natural sciences, COMPASS, Particle identification, Compass, 0103 physical sciences, COMPASS experiment, Computer vision, 010306 general physics, Instrumentation, RICH, Physics, 010308 nuclear & particles physics, business.industry, Detector, Software package, Likelihood algorithms, Pattern recognition (psychology), High Energy Physics::Experiment, Artificial intelligence, business, Photon detection, Data reduction
Abstract

International audience; RICH-1 is a large size RICH detector in operation at the COMPASS experiment since 2001 and recently upgraded implementing a new photon detection system with increased performance.A dedicated software package has been developed to perform RICH-1 data reduction, pattern recognition and particle identification as well as a number of accessory tasks for detector studies.The software package, the algorithms implemented and the detector characterisation and performance are reported in detail.

Published
2011
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8. The experience of building and operating COMPASS RICH-1

Author

P. Abbon, M. Alexeev, H. Angerer, G. Baum, R. Birsa, P. Bordalo, F. Bradamante, A. Bressan, M. Chiosso, P. Ciliberti, M. Colantoni, T. Dafni, S. Dalla Torre, E. Delagnes, O. Denisov, H. Deschamps, N. Dibiase, V. Duic, W. Eyrich, A. Ferrero, M. Finger, H. Fischer, C. Franco, S. Gerassimov, M. Giorgi, B. Gobbo, R. Hagemann, D. von Harrach, F.H. Heinsius, R. Joosten, B. Ketzer, V.N. Kolosov, K. Königsmann, I. Konorov, D. Kramer, F. Kunne, A. Lehmann, S. Levorato, A. Maggiora, A. Magnon, A. Mann, A. Martin, G. Menon, A. Mutter, O. Nähle, F. Nerling, D. Neyret, D. Panzieri, S. Paul, G. Pesaro, C. Pizzolotto, J. Polak, P. Rebourgeard, F. Robinet, E. Rocco, G. Sbrizzai, P. Schiavon, C. Schill, P. Schoenmeier, W. Schröder, M. Slunecka, F. Sozzi, L. Steiger, M. Sulc, M. Svec, S. Takekawa, F. Tessarotto, A. Teufel, H. Wollny, Département d'Electronique, des Détecteurs et d'Informatique pour la Physique (ex SEDI) (DEDIP), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Département de Physique Nucléaire (ex SPhN) (DPHN), P., Abbon, M., Alexeev, H., Angerer, G., Baum, R., Birsa, P., Bordalo, Bradamante, Franco, Bressan, Andrea, M., Chiosso, Ciliberti, Piero, M., Colantoni, T., Dafni, S., Dallatorre, E., Delagne, O., Denisov, H., Deschamp, N., Dibiase, Duic, Venicio, W., Eyrich, A., Ferrero, M., Finger, M., Fingerjr, H., Fischer, C., Franco, S., Gerassimov, Giorgi, Marcello, B., Gobbo, R., Hagemann, D., Vonharrach, F. H., Heinsiu, R., Joosten, B., Ketzer, V. N., Kolosov, K., Koenigsmann, I., Konorov, D., Kramer, F., Kunne, A., Lehmann, Levorato, Stefano, A., Maggiora, A., Magnon, A., Mann, Martin, Anna, G., Menon, A., Mutter, O., Naehle, F., Nerling, D., Neyret, D., Panzieri, S., Paul, Pesaro, Giulia, C., Pizzolotto, J., Polak, P., Rebourgeard, F., Robinet, E., Rocco, Sbrizzai, Giulio, Schiavon, Paolo, C., Schill, P., Schoenmeier, W., Schroeder, M., Slunecka, Sozzi, Federica, L., Steiger, M., Sulc, M., Svec, Takekawa, Stefano, F., Tessarotto, A., Teufel, and H., Wollny

Subjects
Nuclear and High Energy Physics, Cherenkov detector, Physics::Instrumentation and Detectors, [PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex], COMPASS, 01 natural sciences, Particle identification, law.invention, Nuclear physics, CsI, MAPMT, Photon detection, PID, RICH, Instrumentation, Optics, law, Compass, 0103 physical sciences, COMPASS experiment, CsI photoconverter, 010306 general physics, Event reconstruction, Physics, Large Hadron Collider, Spectrometer, 010308 nuclear & particles physics, business.industry, Upgrade, High Energy Physics::Experiment, business
Abstract

COMPASS RICH-1 is a large size gaseous Imaging Cherenkov Detector providing hadron identification in the range from 3 to 55 GeV/c, in the wide acceptance spectrometer of the COMPASS Experiment at CERN SPS. It uses a 3 m long C(4)F(10) radiator, a 21 m(2) large VUV mirror surface and two kinds of photon detectors: MAPMTs and MWPCs with CsI photocathodes, covering a total of 5.5 m(2). It is in operation since 2002 and its performance has increased in time thanks to progressive optimization and mostly to a major upgrade which was implemented in 2006. The main characteristics of COMPASS RICH-1 components are described and some specific aspects related to the radiator gas system, the mirror alignment, the MWPC electrical stability and the readout electronics are discussed. Some key features of the event reconstruction and the PID analysis are presented together with results from the COMPASS RICH-1 performance characterization study. (C) 2010 Elsevier B.V. All rights reserved.

Published
2010
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9. Particle identification with the fast COMPASS RICH-1 detector

Author

P. Abbon, M. Alexeev, H. Angerer, R. Birsa, P. Bordalo, F. Bradamante, A. Bressan, M. Chiosso, P. Ciliberti, M.L. Colantoni, T. Dafni, S. Dalla Torre, E. Delagnes, O. Denisov, H. Deschamps, V. Diaz, N. Dibiase, V. Duic, W. Eyrich, A. Ferrero, M. Finger, H. Fischer, S. Gerassimov, M. Giorgi, B. Gobbo, R. Hagemann, D. von Harrach, F.H. Heinsius, R. Joosten, B. Ketzer, V.N. Kolosov, K. Königsmann, I. Konorov, D. Kramer, F. Kunne, A. Lehmann, S. Levorato, A. Maggiora, A. Magnon, A. Mann, A. Martin, G. Menon, A. Mutter, O. Nähle, F. Nerling, D. Neyret, D. Panzieri, S. Paul, G. Pesaro, C. Pizzolotto, J. Polak, P. Rebourgeard, F. Robinet, E. Rocco, P. Schiavon, C. Schill, W. Schröder, L. Silva, M. Slunecka, F. Sozzi, L. Steiger, M. Sulc, M. Svec, S. Takekawa, F. Tessarotto, A. Teufel, H. Wollny, Département d'Electronique, des Détecteurs et d'Informatique pour la Physique (ex SEDI) (DEDIP), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Département de Physique Nucléaire (ex SPhN) (DPHN), COMPASS, P., Abbon, M., Alexeev, H., Angereri, R., Birsa, P., Bordalo, Bradamante, Franco, Bressan, Andrea, M., Chiosso, Ciliberti, Piero, M. L., Colantoni, T., Dafni, S., Dalla Torre, E., Delagne, O., Denisov, H., Deschamp, V., Diaz, N., Dibiase, Duic, Venicio, W., Eyric, A., Ferrero, M., Finger, M. Finger J., R., H., Fischer, S., Gerassimov, Giorgi, Marcello, B., Gobbo, R., Hageman, D., von Harrach, F. H., Heinsiu, R., Jooste, B., Ketzeri, V. N., Kolosov, K., Königsman, I., Konorovi, D., Kramer, F., Kunne, A., Lehman, Levorato, Stefano, A., Maggiora, A., Magnon, A., Manni, Martin, Anna, G., Menon, A., Mutter, O., Näh, F., Nerling, D., Neyret, D., Panzieri, S., Pauli, Pesaro, Giulia, C., Pizzolotto, J., Pola, P., Rebourgeard, F., Robinet, E., Rocco, Schiavon, Paolo, C., Schill, W., Schröder, L., Silva, M., Slunecka, Sozzi, Federica, L., Steiger, M., Sulc, M., Svec, Takekawa, Stefano, F., Tessarotto, A., Teufeld, and H., Wollny

Subjects
Nuclear and High Energy Physics, Physics::Instrumentation and Detectors, Photon detector, Multi-anode photo-multiplier, ComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISION, High resolution, [PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex], 01 natural sciences, COMPASS, Particle identification, TDC, Optics, Compass, 0103 physical sciences, 010306 general physics, Instrumentation, RICH, Physics, 010308 nuclear & particles physics, business.industry, Detector, Charge (physics), Front-end electronics, Upgrade, High Energy Physics::Experiment, business, Photon detection, Front-end electronic
Abstract

International audience; A new photon detection system for the COMPASS RICH-1 detector has been designed and installed. In the central region, the project is based on multi-anode photo-multiplier technology accompanied by charge sensitive, high resolution and dead-time free time digitization. In the outer area, only the readout electronics for the existing photon detectors has been replaced. Details on the detector upgrade and its performance are presented.

Published
2010
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10. Development of a THGEM-based photon detectorfor RICH applications

Author

M. Alekseev, M. Alfonsi, R. Birsa, M. Chiosso, G. Croci, M. L. Colantoni, S. Dalla Torre, O. Denisov, V. Diaz, N. Dibiase, S. Duarte Pinto, A. Ferrero, M. Finger, M. Finger Jr, H. Fischer, G. Giacomini, B. Gobbo, R. Hagemann, F. H. Heinsius, F. Herrmann, K. Konigsmann, D. Kramer, L. Lauser, A. Maggiora, G. Menon, A. Mutter, F. Nerling, D. Panzieri, J. Polak, E. Rocco, L. Ropelewski, F. Sauli, C. Schill, S. Schopfere, M. Slunecka, L. Steiger, M. Sulc, S. Takekawa, F. Tessarotto, H. Wollny, BRADAMANTE, FRANCO, BRESSAN, Andrea, CILIBERTI, PIERO, DUIC, VENICIO, GIORGI, MARCELLO, LEVORATO, STEFANO, MARTIN, ANNA, PESARO, GIULIA, SBRIZZAI, GIULIO, SCHIAVON, PAOLO, SOZZI, FEDERICA, M., Alekseev, M., Alfonsi, R., Birsa, Bradamante, Franco, Bressan, Andrea, M., Chiosso, Ciliberti, Piero, G., Croci, M. L., Colantoni, S., Dalla Torre, O., Denisov, V., Diaz, N., Dibiase, S., Duarte Pinto, Duic, Venicio, A., Ferrero, M., Finger, M., Finger Jr, H., Fischer, G., Giacomini, Giorgi, Marcello, B., Gobbo, R., Hagemann, F. H., Heinsiu, F., Herrmann, K., Konigsmann, D., Kramer, L., Lauser, Levorato, Stefano, A., Maggiora, Martin, Anna, G., Menon, A., Mutter, F., Nerling, D., Panzieri, Pesaro, Giulia, J., Polak, E., Rocco, L., Ropelewski, F., Sauli, Sbrizzai, Giulio, Schiavon, Paolo, C., Schill, S., Schopfere, M., Slunecka, Sozzi, Federica, L., Steiger, M., Sulc, S., Takekawa, F., Tessarotto, and H., Wollny

Subjects
Detector Thgem
Published
2009

11. The upgrade project of the RICH-1 of the COMPASS Experiment

Author

P. Abbon, M. Alekseev, H. Angerer, R. Birsa, M. Bordalo, L. Busso, M. Chiosso, O. Cobanoglu, M. L. Colantoni, S. Dalla Torre, T. Dafni, E. Delagnes, H. Deshamps, V. Diaz, N. Dibiase, W. Eyrich, D. Faso, A. Ferrero, M. Finger, M. Finger Jr, H. Fischer, S. Gerassimov, B. Gobbo, R. Hagemann, D. von Harrach, F. H. Heinsius, R. Joosten, B. Ketzer, K. Konigsmann, V. N. Kolosov, I. Konorov, F. Kunne, A. Lehmann, A. Maggiora, A. Magnon, A. Mann, G. Mazza, G. Menon, A. Mutter, O. Nahle, F. Nerling, D. Neyret, S. Panebianco, D. Panzieri, S. Paul, J. Polak, D. Rebourgeard, F. Robinet, E. Rocco, C. Schill, W. Schroder, L. Silva, M. Slunecka, F. Sozzi, L. Steiger, M. Sulc, M. Svec, S. Takekawa, F. Tessarotto, A. Teufel, H. Wollny, BRADAMANTE, FRANCO, BRESSAN, Andrea, CILIBERTI, PIERO, DUIC, VENICIO, GIORGI, MARCELLO, LEVORATO, STEFANO, MARTIN, ANNA, PESARO, GIULIA, SCHIAVON, PAOLO, P., Abbon, M., Alekseev, H., Angerer, R., Birsa, M., Bordalo, Bradamante, Franco, Bressan, Andrea, L., Busso, M., Chiosso, Ciliberti, Piero, O., Cobanoglu, M. L., Colantoni, S., Dalla Torre, T., Dafni, E., Delagne, H., Deshamp, V., Diaz, N., Dibiase, Duic, Venicio, W., Eyrich, D., Faso, A., Ferrero, M., Finger, M., Finger Jr, H., Fischer, S., Gerassimov, Giorgi, Marcello, B., Gobbo, R., Hagemann, D., von Harrach, F. H., Heinsiu, R., Joosten, B., Ketzer, K., Konigsmann, V. N., Kolosov, I., Konorov, F., Kunne, A., Lehmann, Levorato, Stefano, A., Maggiora, A., Magnon, A., Mann, Martin, Anna, G., Mazza, G., Menon, A., Mutter, O., Nahle, F., Nerling, D., Neyret, S., Panebianco, D., Panzieri, S., Paul, Pesaro, Giulia, J., Polak, D., Rebourgeard, F., Robinet, E., Rocco, Schiavon, Paolo, C., Schill, W., Schroder, L., Silva, M., Slunecka, F., Sozzi, L., Steiger, M., Sulc, M., Svec, S., Takekawa, F., Tessarotto, A., Teufel, and H., Wollny

Subjects
Compass Experiment
Published
2009

12. A highly integrated low-cost readout system for the COMPASS RICH-1 detector2007 IEEE Nuclear Science Symposium Conference Record

Author

P. Abbon, M. Alekseev, H. Angerer, M. Apollonio, P. Bordalo, L. Busso, M. Chiosso, M. L. Colantoni, S. Costa, T. Dafni, E. Delagnes, H. Deschamps, V. Diaz, N. Dibiase, W. Eyrich, D. Faso, A. Ferrero, M. Finger, H. Fischer, M. Georgi, S. Gerassimov, B. Gobbo, R. Hagemann, D. von Harrach, F. H. Heinsius, R. Joosten, B. Ketzer, V. N. Kolosov, K. Konigsmann, I. Konorov, D. Kramer, F. Kunne, A. Lehmann, A. Maggiora, A. Magnon, A. Mann, G. Menon, A. Mutter, O. Nahle, F. Nerling, D. Neyret, S. Panebianco, D. Panzieri, S. Paul, C. Pizzolotto, J. Polak, P. Rebourgeard, F. Robinet, E. Rocco, C. Schill, W. Schroder, L. Silva, M. Slunecka, L. Steiger, M. Sulc, M. Svec, F. Tessarotto, A. Teufel, H. Wollny, BIRSA, RENATO, BRADAMANTE, FRANCO, BRESSAN, Andrea, CILIBERTI, PIERO, DALLA TORRE, SILVIA, DUIC, VENICIO, LEVORATO, STEFANO, MARTIN, ANNA, PAGANO, PAOLO, PESARO, GIULIA, SCHIAVON, PAOLO, SOZZI, FEDERICA, Bo Yu, P., Abbon, M., Alekseev, H., Angerer, M., Apollonio, Birsa, Renato, P., Bordalo, Bradamante, Franco, Bressan, Andrea, L., Busso, M., Chiosso, Ciliberti, Piero, M. L., Colantoni, S., Costa, T., Dafni, DALLA TORRE, Silvia, E., Delagne, H., Deschamp, V., Diaz, N., Dibiase, Duic, Venicio, W., Eyrich, D., Faso, A., Ferrero, M., Finger, H., Fischer, M., Georgi, S., Gerassimov, B., Gobbo, R., Hagemann, D., von Harrach, F. H., Heinsiu, R., Joosten, B., Ketzer, V. N., Kolosov, K., Konigsmann, I., Konorov, D., Kramer, F., Kunne, A., Lehmann, Levorato, Stefano, A., Maggiora, A., Magnon, A., Mann, Martin, Anna, G., Menon, A., Mutter, O., Nahle, F., Nerling, D., Neyret, Pagano, Paolo, S., Panebianco, D., Panzieri, S., Paul, Pesaro, Giulia, C., Pizzolotto, J., Polak, P., Rebourgeard, F., Robinet, E., Rocco, Schiavon, Paolo, C., Schill, W., Schroder, L., Silva, M., Slunecka, Sozzi, Federica, L., Steiger, M., Sulc, M., Svec, F., Tessarotto, A., Teufel, and H., Wollny

Subjects
Photons, Readout systems, Photodetectors, Field emission cathodes, Detectors, Detectors, Field emission cathodes, Particle beams, Photodetectors, Photomultipliers, Photons, Readout systems, Particle beams, Photomultipliers
Abstract

Particle identification at high multiplicities is a key feature of the COMPASS experiment at CERN's SPS. Hadrons up to 50 GeV/c are identified by a RICH detector with a large horizontal and vertical acceptance of ±250 mrad and ±180 mrad, respectively. The central region of the photon detector is equipped with multi-anode photomultiplier tubes, the remaining 75% of the total active area are covered by MWPCs with CsI photocathodes. In order to improve the performance of the detector at very high beam intensities, more than 62000 channels of a new analog readout system of file MWPCs, based on the APV25 chip, were developed and installed in 2006. The new system features good single photon detection efficiency due to its low noise, negligible dead time at trigger rates up to 50 kHz, and low cost. In addition, sampling of the MWPC signal allows us to measure the signal time with a resolution of about 30 ns or better. The architecture of the new readout system as well as the performance results of the RICH-1 detector in the outer region during 2006 COMPASS run will be discussed

Published
2007

13. Telemedicine in the treatment of diabetic pregnancy

Author

E. Borrello, E. Sciullo, Angela Napoli, A. Sabbatini, N. DiBiase, and F. Fallucca

Subjects
medicine.medical_specialty, Telemedicine, Fetus, Every Two Weeks, Perinatal mortality, business.industry, Endocrinology, Diabetes and Metabolism, medicine.disease, law.invention, Surgery, Randomized controlled trial, law, Metabolic control analysis, Diabetes mellitus, Emergency medicine, Internal Medicine, medicine, business, Diabetic pregnancy
Abstract

Good diabetic patient control requires that treatment be continuously adapted to the patient's behaviour and the control achieved, in order to get the glucose level within a predetermined target range. Several approaches have been documented. Self-monitoring of blood glucose (SMBG) has become a major element in the care of individuals with diabetes mellitus. In managing the pregnant diabetic patient it must be considered that two patients are being treated: the mother and the fetus. It appears that the strict maintenance of euglycaemia before conception and during the prenatal period may favourably influence perinatal mortality and morbidity. Assuming that easy access to diabetes care providers would allow patients to make appropriate adjustments to their management and thus improve their metabolic control, a controlled trial comparing customary management with continuous diabetes care providing access to patients' self-monitored glucose data, was undertaken in diabetic pregnancy. In the study, two groups were compared. The Dianet group (7 diabetic pregnant women) used a Diva System: they stored their data in blood glucose meters (ROMEO) with memory to store and transmit data when inserted into JULIET, and this data was directly carried through a telephone modem (JULIET + BOXTEL) to our service every week, and they came to the clinic every two weeks. The control group (10 pregnant diabetic women) recorded their data in a diary and came to the diabetes clinic every week. The use of the telphone modem (DIANET system) stimulated both the patient and the diabetes specialist to keep closer control of blood glucose levels. This might be especially useful in the treatment of diabetes in pregnancy because the patients are usually highly motivated to achieve better metabolic control, as was shown by (a) faster optimisation of blood glucose profiles, (b) better pre-breakfast and pre-lunch blood glucose concentration, (c) fewer hypoglycaemic episodes, in the DIANET versus the control group.

Published
1996
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14. The COMPASS RICH-1 detector upgrade

Author

P. Abbon, M. Alekseev, H. Angerer, M. Apollonio, R. Birsa, P. Bordalo, F. Bradamante, A. Bressan, L. Busso, M. Chiosso, P. Ciliberti, M. L. Colantoni, S. Costa, S. Dalla Torre, T. Dafni, E. Delagnes, H. Deschamps, V. Diaz, N. Dibiase, V. Duic, W. Eyrich, D. Faso, A. Ferrero, M. Finger, H. Fischer, S. Gerassimov, M. Giorgi, B. Gobbo, R. Hagemann, D. von Harrach, F. H. Heinsius, R. Joosten, B. Ketzer, K. Königsmann, V. N. Kolosov, I. Konorov, D. Kramer, F. Kunne, A. Lehmann, S. Levorato, A. Maggiora, A. Magnon, A. Mann, A. Martin, G. Menon, A. Mutter, O. Nähle, F. Nerling, D. Neyret, P. Pagano, S. Panebianco, D. Panzieri, S. Paul, G. Pesaro, J. Polak, P. Rebourgeard, F. Robinet, E. Rocco, P. Schiavon, C. Schill, W. Schröder, L. Silva, M. Slunecka, F. Sozzi, L. Steiger, M. Sulc, M. Svec, F. Tessarotto, A. Teufel, H. Wollny, Abbon, P, Alekseev, M, Angerer, H, Apollonio, M, Birsa, R, Bordalo, P, Bradamante, F, Bressan, Andrea, Busso, L, Chiosso, M, Ciliberti, Piero, COLANTONI M., L, Costa, S, DALLA TORRE, S, Dafni, T, Delagnes, E, Deschamps, H, Diaz, V, Dibiase, N, Duic, V, Eyrich, W, Faso, D, Ferrero, A, Finger, M, FINGER M., Jr, Fischer, H, Gerassimov, S, Giorgi, M, Gobbo, B, Hagemann, R, VON HARRACH, D, HEINSIUS F., H, Joosten, R, Ketzer, B, Königsmann, K, KOLOSOV V., N, Konorov, I, Kramer, D, Kunne, F, Lehmann, A, Levorato, S, Maggiora, A, Magnon, A, Mann, A, Martin, Anna, Menon, G, Mutter, A, Nähle, O, Nerling, F, Neyret, D, Pagano, P, Panebianco, S, Panzieri, D, Paul, S, Pesaro, G, Polak, J, Rebourgeard, P, Robinet, F, Rocco, E, Schiavon, Paolo, Schill, C, Schröder, W, Silva, L, Slunecka, M, Sozzi, F, Steiger, L, Sulc, M, Svec, M, Tessarotto, F, Teufel, A, and Wollny, H.

Subjects
Physics, Photomultiplier, Physics::Instrumentation and Detectors, business.industry, Cherenkov detector, Detector, General Physics and Astronomy, Ring-imaging Cherenkov detector, law.invention, Nuclear physics, Upgrade, Optics, law, Compass, COMPASS experiment, High Energy Physics::Experiment, General Materials Science, Physical and Theoretical Chemistry, business, Cherenkov radiation
Abstract

The COMPASS experiment at CERN provides hadron identification in a wide momentum range employing a large size gaseous Ring Imaging CHerenkov detector (RICH). The presence of large uncorrelated background in the COMPASS environment was limiting the efficiency of COMPASS RICH-1 in the very forward regime. A major upgrade of RICH-1 required a new technique for Cherenkov photon detection at count rates of several 106/s per channel in the central detector part, and a read-out system allowing for trigger rates of up to 100 kHz. To cope with these requirements, the photon detectors of the central region have been replaced with a fast photon detection system described here, while, in the peripheral regions, the existing multi-wire proportional chambers with CsI photo-cathodes have been equipped with a new read-out system based on APV preamplifiers and flash ADC chips. The new system consists of multi-anode photomultiplier tubes (MAPMTs) coupled to individual fused silica lens telescopes, and fast read-out electronics based on the MAD4 amplifier-discriminator and the dead-time free F1 TDC chip. The project was completely designed and implemented in less than two years: The upgraded detector is in operation since the 2006 CERN SPS run. We present the photon detection design, constructive aspects and test studies to characterise the single photon response of the MAPMTs coupled to the read-out system as well as the detector performance based on the 2006 data.

Published
2008

15. Pattern recognition and PID for COMPASS RICH-1

Author

P. Abbon, M. Alexeev, H. Angerer, R. Birsa, P. Bordalo, F. Bradamante, A. Bressan, M. Chiosso, P. Ciliberti, M.L. Colantoni, T. Dafni, S. Dalla Torre, E. Delagnes, O. Denisov, H. Deschamps, V. Diaz, N. Dibiase, V. Duic, W. Eyrich, A. Ferrero, M. Finger, H. Fischer, S. Gerassimov, M. Giorgi, B. Gobbo, R. Hagemann, D. von Harrach, F.H. Heinsius, R. Joosten, B. Ketzer, V.N. Kolosov, K. Königsmann, I. Konorov, D. Kramer, F. Kunne, A. Lehmann, S. Levorato, A. Maggiora, A. Magnon, A. Mann, A. Martin, G. Menon, A. Mutter, O. Nähle, F. Nerling, D. Neyret, D. Panzieri, S. Paul, G. Pesaro, C. Pizzolotto, J. Polak, P. Rebourgeard, F. Robinet, E. Rocco, P. Schiavon, C. Schill, P. Schoenmeier, W. Schröder, L. Silva, M. Slunecka, F. Sozzi, L. Steiger, M. Sulc, M. Svec, S. Takekawa, F. Tessarotto, A. Teufel, H. Wollny, Abbon, P, Alexeev, M, Angerer, H, Birsa, R, Bordalo, P, Bradamante, F, Bressan, Andrea, Chiosso, M, Ciliberti, Piero, COLANTONI M., L, Dafni, T, DALLA TORRE, S, Delagnes, E, Denisov, O, Deschamps, H, Diaz, V, Dibiase, N, Duic, V, Eyrich, W, Ferrero, A, Finger, M, FINGER M., Jr, Fischer, H, Gerassimov, S, Giorgi, M, Gobbo, B, Hagemann, R, VON HARRACH, D, HEINSIUS F., H, Joosten, R, Ketzer, B, KOLOSOV V., N, Königsmann, K, Konorov, I, Kramer, D, Kunne, F, Lehmann, A, Levorato, Stefano, Maggiora, A, Magnon, A, Mann, A, Martin, Anna, Menon, G, Mutter, A, Nähle, O, Nerling, F, Neyret, D, Panzieri, D, Paul, S, Pesaro, G, Pizzolotto, C, Polak, J, Rebourgeard, P, Robinet, F, Rocco, E, Schiavon, Paolo, Schill, C, Schoenmeier, P, Schröder, W, Silva, L, Slunecka, M, Sozzi, F, Steiger, L, Sulc, M, Svec, M, Takekawa, Stefano, Tessarotto, F, Teufel, A, and Wollny, H.

Subjects
Physics, Nuclear and High Energy Physics, Photomultiplier, Physics - Instrumentation and Detectors, business.industry, Photon detector, Detector, PID controller, FOS: Physical sciences, Pattern recognition, Instrumentation and Detectors (physics.ins-det), Photon yield, Particle identification, High Energy Physics - Experiment, High Energy Physics - Experiment (hep-ex), Compass, Pattern recognition (psychology), Artificial intelligence, Detectors and Experimental Techniques, business, Instrumentation
Abstract

A package for pattern recognition and PID by COMPASS RICH-1 has been developed and used for the analysis of COMPASS data collected in the years 2002 to 2004, and 2006-2007 with the upgraded RICH-1 photon detectors. It has allowed the full characterization of the detector in the starting version and in the upgraded one, as well as the PID for physics results. We report about the package structure and algorithms, and the detector characterization and PID results., 4 pages, 4 figures,to appear in the proceedings of 6th International Workshop on Ring Imaging Cherenkov Counters (RICH 2007), Trieste, Italy, 15-20 Oct 2007

Published
2008

16. Read-out electronics for fast photon detection with COMPASS RICH-1

Author

P. Abbon, M. Alexeev, H. Angerer, R. Birsa, P. Bordalo, F. Bradamante, A. Bressan, M. Chiosso, P. Ciliberti, M. Colantoni, T. Dafni, S. Dalla Torre, E. Delagnes, O. Denisov, H. Deschamps, V. Diaz, N. Dibiase, V. Duic, W. Eyrich, A. Ferrero, M. Finger, H. Fischer, S. Gerassimov, M. Giorgi, B. Gobbo, R. Hagemann, D. von Harrach, F.H. Heinsius, R. Joosten, B. Ketzer, V.N. Kolosov, K. Königsmann, I. Konorov, D. Kramer, F. Kunne, A. Lehmann, S. Levorato, A. Maggiora, A. Magnon, A. Mann, A. Martin, G. Menon, A. Mutter, O. Nähle, F. Nerling, D. Neyret, D. Panzieri, S. Paul, G. Pesaro, C. Pizzolotto, J. Polak, P. Rebourgeard, F. Robinet, E. Rocco, P. Schiavon, C. Schill, P. Schoenmeier, W. Schröder, L. Silva, M. Slunecka, F. Sozzi, L. Steiger, M. Sulc, M. Svec, S. Takekawa, F. Tessarotto, A. Teufel, and H. Wollny

Subjects
Physics, Nuclear and High Energy Physics, Photomultiplier, business.industry, Detector, Chip, Particle identification, Optics, Compass, COMPASS experiment, Electronics, business, Instrumentation, Photon detection
Abstract

A new read-out electronics system has been developed for the fast photon detection of the central region of the COMPASS RICH-1. The project is based on multi-anode photomultipliers read out by the high-sensitivity MAD4 preamplifier-discriminator and the dead-time free F1 TDC chip characterised by high time resolution. The system has been designed taking into account the high photon flux in the central region of the detector and the high rate requirement of the COMPASS experiment. The system is described in detail together with the measured performances. The new electronics system has been installed and used for the 2006 data taking; it entirely fulfils the expected performances.

Published
2008

17. The characterisation of the multianode photomultiplier tubes for the RICH-1 upgrade project at COMPASS

Author

P. Abbon, M. Alexeev, H. Angerer, R. Birsa, P. Bordalo, F. Bradamante, A. Bressan, M. Chiosso, P. Ciliberti, M.L. Colantoni, T. Dafni, S. Dalla Torre, E. Delagnes, O. Denisov, H. Deschamps, V. Diaz, N. Dibiase, V. Duic, W. Eyrich, A. Ferrero, M. Finger, H. Fischer, S. Gerassimov, M. Giorgi, B. Gobbo, R. Hagemann, D. von Harrach, F.H. Heinsius, R. Joosten, B. Ketzer, V.N. Kolosov, K. Königsmann, I. Konorov, D. Kramer, F. Kunne, A. Lehmann, S. Levorato, A. Maggiora, A. Magnon, A. Mann, A. Martin, G. Menon, A. Mutter, O. Nähle, F. Nerling, D. Neyret, D. Panzieri, S. Paul, G. Pesaro, C. Pizzolotto, J. Polak, P. Rebourgeard, F. Robinet, E. Rocco, P. Schiavon, C. Schill, P. Schoenmeier, W. Schroeder, L. Silva, M. Slunecka, F. Sozzi, L. Steiger, M. Sulc, M. Svec, S. Takekawa, F. Tessarotto, A. Teufel, H. Wollny, Abbon, P, Alexeev, M, Angerer, H, Birsa, R, Bordalo, P, Bradamante, F, Bressan, Andrea, Chiosso, M, Ciliberti, Piero, COLANTONI M., L, Dafni, T, DALLA TORRE, S, Delagnes, E, Denisov, O, Deschamps, H, Diaz, V, Dibiase, N, Duic, V, Eyrich, W, Ferrero, A, Finger, M, FINGER M., Jr, Fischer, H, Gerassimov, S, Giorgi, M, Gobbo, B, Hagemann, R, VON HARRACH, D, HEINSIUS F., H, Joosten, R, Ketzer, B, KOLOSOV V., N, Königsmann, K, Konorov, I, Kramer, D, Kunne, F, Lehmann, A, Levorato, Stefano, Maggiora, A, Magnon, A, Mann, A, Martin, Anna, Menon, G, Mutter, A, Nähle, O, Nerling, F, Neyret, D, Panzieri, D, Paul, S, Pesaro, G, Pizzolotto, C, Polak, J, Rebourgeard, P, Robinet, F, Rocco, E, Schiavon, Paolo, Schill, C, Schoenmeier, P, Schroeder, W, Silva, L, Slunecka, M, Sozzi, F, Steiger, L, Sulc, M, Svec, M, Takekawa, Stefano, Tessarotto, F, Teufel, A, and Wollny, H.

Subjects
Physics, Nuclear and High Energy Physics, Photomultiplier, Photon, Physics::Instrumentation and Detectors, business.industry, Detector, Optics, Upgrade, Compass, Quantum efficiency, business, Instrumentation, Cherenkov radiation, Dark current
Abstract

A major upgrade of the Cherenkov photon detection system of COMPASS RICH-1 has been performed and it has been in operation since the 2006 physics run. The inner part of the photon detector has been replaced by a different technology in order to measure Cherenkov photons at high photoelectron rates, up to several times 10 6 per second and per channel. Cherenkov photons from 200 to 750 nm are detected by 576 multianode photomultiplier tubes (MAPMTs) with 16 channels each, coupled to individual fused silica lens telescopes and fast, high sensitivity and high time resolution electronics read-out. To guarantee an optimal performance of the complete system, parameters like dark current, gain, uniformity, relative quantum efficiency have been measured for a totality of more than 600 MAPMTs (about 10 000 channels) in a fully automated test-stand, developed for this purpose. The ideal working point for each individual pixel could be ascertained by these measurements. In 2006 the newly equipped detector exhibited an excellent performance: about 56 detected photons per ring at saturation and a time resolution of better than 1 ns. We report about the MAPMT characterisation and the quality control set-up, protocol and results.

Published
2008

18. Fast photon detection for COMPASS RICH-1

Author

P. Abbon, M. Alekseev, H. Angerer, M. Apollonio, R. Birsa, P. Bordalo, F. Bradamante, A. Bressan, L. Busso, M. Chiosso, P. Ciliberti, M.L. Colantoni, S. Costa, N. Dibiase, T. Dafni, S. Dalla Torre, V. Diaz, V. Duic, E. Delagnes, H. Deschamps, W. Eyrich, D. Faso, A. Ferrero, M. Finger, H. Fischer, S. Gerassimov, M. Giorgi, B. Gobbo, D. von Harrach, F.H. Heinsius, R. Joosten, B. Ketzer, K. Königsmann, V.N. Kolosov, I. Konorov, D. Kramer, F. Kunne, S. Levorato, A. Maggiora, A. Magnon, A. Mann, A. Martin, G. Menon, A. Mutter, O. Nähle, D. Neyret, F. Nerling, P. Pagano, S. Paul, S. Panebianco, D. Panzieri, G. Pesaro, C. Pizzolotto, J. Polak, P. Rebourgeard, E. Rocco, F. Robinet, P. Schiavon, C. Schill, P. Schoenmeier, L. Silva, M. Slunecka, L. Steiger, F. Sozzi, M. Sulc, M. Svec, F. Tessarotto, A. Teufel, H. Wollny, Abbon, P, Alekseev, M, Angerer, H, Apollonio, M, Birsa, R, Bordalo, P, Bradamante, Franco, Bressan, Andrea, Busso, L, Chiosso, M, Ciliberti, Piero, COLANTONI M., L, Costa, S, Dibiase, N, Dafni, T, TORRE S., Dalla, Diaz, V, Duic, V, Delagnes, E, Deschamps, H, Eyrich, W, Faso, D, Ferrero, A, Finger, M, FINGER M., Jr, Fischer, H, Gerassimov, S, Giorgi, Marcello, Gobbo, B, VON HARRACH, D, HEINSIUS F., H, Joosten, R, Ketzer, B, Königsmann, K, KOLOSOV V., N, Konorov, I, Kramer, D, Kunne, F, Levorato, Stefano, Maggiora, A, Magnon, A, Mann, A, Martin, Anna, Menon, G, Mutter, A, Nähle, O, Neyret, D, Nerling, F, Pagano, P, Paul, S, Panebianco, S, Panzieri, D, Pesaro, G, Pizzolotto, C, Polak, J, Rebourgeard, P, Rocco, E, Robinet, F, Schiavon, Paolo, Schill, C, Schoenmeier, P, Silva, L, Slunecka, M, Steiger, L, Sozzi, F, Sulc, M, Svec, M, Tessarotto, F, Teufel, A, and Wollny, H.

Subjects
Physics, Nuclear and High Energy Physics, Photomultiplier, business.industry, UV lenses, Emphasis (telecommunications), Detector, COMPASS, Photocathode, Optics, Upgrade, Photon detection, Compass, RICH, Multianode photomultiplier tubes, Systems design, Electronics, business, Instrumentation
Abstract

A fast photon detection system has been built and assembled for the upgrade of COMPASS RICH-1. The system is based on multianode photomultipliers coupled to fused silica lenses to collect the light from a larger surface and to guide it to the photocathode, preserving the position information. The emphasis is on the fast response and high rate capability of the detectors and the associated electronics. The photon detection system is now ready and it will be employed in the 2006 COMPASS data taking. We report about the system design and construction.

Published
2007

19. The fast photon detection system of COMPASS RICH-1

Author

P. Abbon, M. Alekseev, H. Angerer, M. Apollonio, R. Birsa, P. Bordalo, F. Bradamante, A. Bressan, L. Busso, M. Chiosso, P. Ciliberti, M.L. Colantoni, S. Costa, T. Dafni, S. Dalla Torre, E. Delagnes, H. Deschamps, V. Diaz, N. Dibiase, V. Duic, W. Eyrich, D. Faso, A. Ferrero, M. Finger, H. Fischer, S. Gerassimov, M. Giorgi, B. Gobbo, D. von Harrach, F.H. Heinsius, R. Joosten, B. Ketzer, V.N. Kolosov, K. Königsmann, I. Konorov, D. Kramer, F. Kunne, A. Lehmann, S. Levorato, A. Maggiora, A. Magnon, A. Mann, A. Martin, G. Menon, A. Mutter, O. Nähle, F. Nerling, D. Neyret, P. Pagano, S. Panebianco, D. Panzieri, S. Paul, G. Pesaro, C. Pizzolotto, J. Polak, P. Rebourgeard, E. Rocco, F. Robinet, P. Schiavon, C. Schill, P. Schoenmeier, W. Schröder, L. Silva, M. Slunecka, F. Sozzi, L. Steiger, M. Sulc, M. Svec, F. Tessarotto, A. Teufel, H. Wollny, Abbon, P., Alekseev, M., Angerer, H., Apollonio, M., Birsa, R., Bordalo, P., Bradamante, F., Bressan, A., Busso, L., Chiosso, M., Ciliberti, P., Colantoni, M. L., Costa, S., Dafni, T., Dalla Torre, S., Delagnes, E., Deschamps, H., Diaz, V., Dibiase, N., Duic, V., Eyrich, W., Faso, D., Ferrero, A., Finger, M., Finger Jr., M., Fischer, H., Gerassimov, S., Giorgi, M., Gobbo, B., von Harrach, D., Heinsius, F. H., Joosten, R., Ketzer, B., Kolosov, V. N., Königsmann, K., Konorov, I., Kramer, D., Kunne, F., Lehmann, A., Levorato, S., Maggiora, A., Magnon, A., Mann, A., Martin, A., Menon, G., Mutter, A., Nähle, O., Nerling, F., Neyret, D., Pagano, P., Panebianco, S., Panzieri, D., Paul, S., Pesaro, G., Pizzolotto, Cecilia, Polak, J., Rebourgeard, P., Rocco, E., Robinet, F., Schiavon, P., Schill, C., Schoenmeier, P., Schröder, W., Silva, L., Slunecka, M., Sozzi, F., Steiger, L., Sulc, M., Svec, M., Tessarotto, F., Teufel, A., Wollny, H., Abbon, P, Alekseev, M, Angerer, H, Apollonio, M, Birsa, R, Bordalo, P, Bradamante, F, Bressan, Andrea, Busso, L, Chiosso, M, Ciliberti, Piero, COLANTONI M., L, Costa, S, Dafni, T, DALLA TORRE, S, Delagnes, E, Deschamps, H, Diaz, V, Dibiase, N, Duic, V, Eyrich, W, Faso, D, Ferrero, A, Finger, M, FINGER M., Jr, Fischer, H, Gerassimov, S, Giorgi, M, Gobbo, B, VON HARRACH, D, HEINSIUS F., H, Joosten, R, Ketzer, B, KOLOSOV V., N, Königsmann, K, Konorov, I, Kramer, D, Kunne, F, Lehmann, A, Levorato, Stefano, Maggiora, A, Magnon, A, Mann, A, Martin, Anna, Menon, G, Mutter, A, Nähle, O, Nerling, F, Neyret, D, Pagano, P, Panebianco, S, Panzieri, D, Paul, S, Pesaro, G, Pizzolotto, C, Polak, J, Rebourgeard, P, Rocco, E, Robinet, F, Schiavon, Paolo, Schill, C, Schoenmeier, P, Schröder, W, Silva, L, Slunecka, M, Sozzi, F, Steiger, L, Sulc, M, Svec, M, Tessarotto, F, and Teufel, A

Subjects
Photomultiplier, Nuclear and High Energy Physics, Photon, Multi-anode photomultiplier tubes, Physics::Instrumentation and Detectors, UV lenses, COMPASS, Photon detection, RICH, Instrumentation, law.invention, FAST-RICH, DEUTERON, READOUT, DESIGN, Optics, law, Multi-anode photomultiplier tube, Compass, COMPASS experiment, Nuclear and High Energy Physic, Physics, Large Hadron Collider, business.industry, Detector, Lens (optics), Upgrade, UV lense, High Energy Physics::Experiment, business
Abstract

A fast photon detection system has been built for the upgrade of COMPASS RICH-1, the large size gaseous RICH detector in use at the COMPASS Experiment at the CERN SPS since 2001. The photon detectors of the central region have been replaced by a new system based on multi-anode photomultipliers coupled to individual fused silica lens telescopes and a fast readout electronics system, while in the outer region the existing MWPCs with CsI photocathodes have been equipped with a new readout system, based on the APV chip. RICH-1 has been successfully operated in its upgraded version during the 2006 run. We report on the upgrade design and construction, and on the preliminary characterization of the upgraded RICH-1 performances: at saturation about 60 photons per ring have routinely been obtained and the background level has drastically been reduced thanks to the good time resolution of the new system, leading to a 2 σ π –K separation above 55 GeV/c.

Published
2007

20. A highly integrated low-cost readout system for the COMPASS RICH-1 detector

Author

P. Abbon, M. Alekseev, H. Angerer, M. Apollonio, R. Birsa, P. Bordalo, F. Bradamante, A. Bressan, L. Busso, M. Chiosso, P. Ciliberti, M. L. Colantoni, S. Costa, T. Dafni, S. Dalla Torre, E. Delagnes, H. Deschamps, V. Diaz, N. Dibiase, V. Duic, W. Eyrich, D. Faso, A. Ferrero, M. Finger, H. Fischer, M. Georgi, S. Gerassimov, B. Gobbo, R. Hagemann, D. von Harrach, F. H. Heinsius, R. Joosten, B. Ketzer, V. N. Kolosov, K. Konigsmann, I. Konorov, D. Kramer, F. Kunne, A. Lehmann, S. Levorato, A. Maggiora, A. Magnon, A. Mann, A. Martin, G. Menon, A. Mutter, O. Nahle, F. Nerling, D. Neyret, P. Pagano, S. Panebianco, D. Panzieri, S. Paul, G. Pesaro, C. Pizzolotto, J. Polak, P. Rebourgeard, F. Robinet, E. Rocco, P. Schiavon, C. Schill, W. Schroder, L. Silva, M. Slunecka, F. Sozzi, L. Steiger, M. Sulc, M. Svec, F. Tessarotto, A. Teufel, and H. Wollny

Subjects
Physics, Photomultiplier, Physics::Instrumentation and Detectors, business.industry, Detector, Photodetector, Dead time, Particle identification, Nuclear physics, Optics, Compass, Nuclear electronics, COMPASS experiment, High Energy Physics::Experiment, business
Abstract

Particle identification at high multiplicities is a key feature of the COMPASS experiment at CERN's SPS. Hadrons up to 50 GeV/c are identified by a RICH detector with a large horizontal and vertical acceptance of plusmn250 mrad and plusmn180 mrad, respectively. The central region of the photon detector is equipped with multi-anode photomultiplier tubes, the remaining 75% of the total active area are covered by MWPCs with Csl photocathodes. In order to improve the performance of the detector at very high beam intensities, more than 62000 channels of a new analog readout system of the MWPCs, based on the APV25 chip, were developed and installed in 2006. The new system features good single photon detection efficiency due to its low noise, negligible dead time at trigger rates up to 50 kHz, and low cost. In addition, sampling of the MWPC signal allows us to measure the signal time with a resolution of about 30 ns or better. The architecture of the new readout system as well as the performance results of the RICH-1 detector in the outer region during 2006 COMPASS run will be discussed.

Published
2007
Full Text
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21. Fast photon detection for the COMPASS RICH detector

Author

P. Abbon, M. Alekseev, H. Angerer, M. Apollonio, R. Birsa, P. Bordalo, F. Bradainante, A. Bressan, L. Busso, M. Chiosso, P. Ciliberti, M.L. Colantoni, S. Costa, S. Dalla Torre, T. Dafni, E. Delagnes, H. Deschamps, V. Diaz, N. Dibiase, V. Duic, W. Eyrich, D. Faso, A. Ferrero, M. Finger, H. Fischer, S. Gerassimov, M. Giorgi, B. Gobbo, R. Hagemann, D. von Harrach, F.H. Heinsius, R. Joosten, B. Ketzer, K. Königsmann, V.N. Kolosov, I. Konorov, D. Kramer, F. Kunne, A. Lehmann, S. Levorato, A. Maggiora, A. Magnon, A. Mann, A. Martin, G. Menon, A. Mutter, O. Nähle, F. Nerling, D. Neyret, P. Pagano, S. Panebianco, D. Panzieri, S. Paul, G. Pesaro, J. Polak, P. Rebourgeard, F. Robinet, E. Rocco, P. Schiavon, C. Schill, W. Schröder, L. Silva, M. Slunecka, F. Sozzi, L. Steiger, M. Sulc, M. Svec, F. Tessarotto, A. Teufel, H. Wollny, Abbon, P, Alekseev, M, Angerer, H, Apollonio, M, Birsa, R, Bordalo, P, Bradamante, Franco, Bressan, Andrea, Busso, L, Chiosso, M, Ciliberti, Piero, COLANTONI M., L, Costa, S, DALLA TORRE, S, Dafni, T, Delagnes, E, Deschamps, H, Diaz, V, Dibiase, N, Duic, V, Eyrich, W, Faso, D, Ferrero, A, Finger, M, FINGER M., Jr, Fischer, H, Gerassimov, S, Giorgi, Marcello, Gobbo, B, Hagemann, R, VON HARRACH, D, HEINSIUS F., H, Joosten, R, Ketzer, B, Königsmann, K, KOLOSOV V., N, Konorov, I, Kramer, D, Kunne, F, Lehmann, A, Levorato, Stefano, Maggiora, A, Magnon, A, Mann, A, Martin, Anna, Menon, G, Mutter, A, Nähle, O, Nerling, F, Neyret, D, Pagano, P, Panebianco, S, Panzieri, D, Paul, S, Pesaro, G, Polak, J, Rebourgeard, P, Robinet, F, Rocco, E, Schiavon, Paolo, Schill, C, Schröder, W, Silva, L, Slunecka, M, Sozzi, F, Steiger, L, Sulc, M, Svec, M, Tessarotto, F, Teufel, A, and Wollny, H.

Subjects
Physics, Nuclear and High Energy Physics, Photomultiplier, Physics - Instrumentation and Detectors, Photon, Large Hadron Collider, business.industry, Physics::Instrumentation and Detectors, Detector, Other Fields of Physics, FOS: Physical sciences, Instrumentation and Detectors (physics.ins-det), Atomic and Molecular Physics, and Optics, Ring-imaging Cherenkov detector, Optics, Compass, COMPASS experiment, High Energy Physics::Experiment, Detectors and Experimental Techniques, business, Cherenkov radiation
Abstract

The COMPASS experiment at the SPS accelerator at CERN uses a large scale Ring Imaging CHerenkov detector (RICH) to identify pions, kaons and protons in a wide momentum range. For the data taking in 2006, the COMPASS RICH has been upgraded in the central photon detection area (25% of the surface) with a new technology to detect Cherenkov photons at very high count rates of several 10^6 per second and channel and a new dead-time free read-out system, which allows trigger rates up to 100 kHz. The Cherenkov photons are detected by an array of 576 visible and ultra-violet sensitive multi-anode photomultipliers with 16 channels each. The upgraded detector showed an excellent performance during the 2006 data taking., Proceeding of the IPRD06 conference (Siena, Okt. 06)

Published
2006

22. TNF-alpha blockade induce clinical remission in patients affected by polymyalgia rheumatica associated to diabetes mellitus and/or osteoporosis: a seven cases report

Author

A, Migliore, U, Massafra, E, Carloni, C, Padalino, S, Martin Martin, F, Lasaracina, N, Dibiase, A, Alimonti, and M, Granata

Subjects
Aged, 80 and over, Tumor Necrosis Factor-alpha, Remission Induction, Antibodies, Monoclonal, Infliximab, Diabetes Mellitus, Type 1, Treatment Outcome, Diabetes Mellitus, Type 2, Polymyalgia Rheumatica, Antirheumatic Agents, Humans, Osteoporosis, Female, Aged
Abstract

Polymyalgia rheumatica (PMR) is a chronic inflammatory condition of the elderly, characterized by aching and morning stiffness in the cervical region, shoulders and pelvic girdles. A steroid treatment course of 6-24 months is often required, but, due to important side effects, it is troublesome if the PMR patient is also affected by diabetes mellitus (DM) and/or osteoporosis. Aim of our study is to test anti-TNF alpha treatment as a steroid sparing tool in PMR patients affected by DM or osteoporosis. In particular, we hypothesise that TNF alpha blockade can be useful not only in remission maintaining, but also in the induction of clinical remission without corticosteroids in this kind of patients. In a six months follow up, patients had clinical improvement, confirmed by physical medical examination, and a statistically significant reduction in ESR and CRP mean values. Anti-TNF alpha treatment was well tolerated by all patients. These preliminary data suggest than Infliximab can be useful in the treatment of PMR patients, not only for steroid sparing purposes, but also as first line therapy in PMR patients with severe comorbidity, such as diabetes mellitus or osteoporosis.

Published
2006

23. Design and status of COMPASS FAST-RICH

Author

P. Abbon, M. Alekseev, H. Angerer, M. Apollonio, R. Birsa, P. Bordalo, F. Bradamante, A. Bressan, L. Busso, M. Chiosso, P. Ciliberti, M.L. Colantoni, S. Costa, S. Dalla Torre, E. Delagnes, H. Deschamps, V. Diaz, N. Dibiase, V. Duic, W. Eyrich, D. Faso, A. Ferrero, M. Finger, H. Fisher, S. Gerassimov, M. Giorgi, B. Gobbo, D. von Harrach, F.H. Heinsius, S. Horikawa, R. Joosten, B. Ketzer, K. Königsmann, I. Konorov, D. Kramer, F. Kunne, A. Lehmann, A. Maggiora, A. Magnon, A. Martin, G. Menon, A. Mutter, O. Nähle, D. Neyret, P. Pagano, S. Panebianco, D. Panzieri, S. Paul, J. Polak, P. Rebourgeard, P. Schiavon, C. Schill, W. Schröder, L. Silva, M. Slunecka, F. Sozzi, L. Steiger, M. Sulc, F. Tessarotto, A. Teufel, Abbon, P, Alekseev, M, Angerer, H, Apollonio, M, Birsa, R, Bordalo, P, Bradamante, F, Bressan, Andrea, Busso, L, Chiosso, M, Ciliberti, Piero, COLANTONI M., L, Costa, S, DALLA TORRE, S, Delagnes, E, Deschamps, H, Diaz, V, Dibiase, N, Duic, V, Eyrich, W, Faso, D, Ferrero, A, Finger, M, FINGER M., Jr, Fisher, H, Gerassimov, S, Giorgi, Marcello, Gobbo, B, VON HARRACH, D, HEINSIUS F., H, Horikawa, S, Joosten, R, Ketzer, B, Königsmann, K, Konorov, I, Kramer, D, Kunne, F, Lehmann, A, Maggiora, A, Magnon, A, Martin, Anna, Menon, G, Mutter, A, Nähle, O, Neyret, D, Pagano, P, Panebianco, S, Panzieri, D, Paul, S, Polak, J, Rebourgeard, P, Schiavon, Paolo, Schill, C, Schröder, W, Silva, L, Slunecka, M, Sozzi, F, Steiger, L, Sulc, M, Tessarotto, F, and Teufel, A.

Subjects
Physics, Nuclear and High Energy Physics, Photomultiplier, business.industry, Context (language use), Photodetection, Chip, Photocathode, Optics, Upgrade, Compass, Electronics, business, Instrumentation
Abstract

In the context of the upgrade of COMPASS RICH-1, we are developing a fast photodetection system for RICH counters, based on UV extended Multi-Anode PhotoMultiplier Tubes (MAPMT) and a custom, low dead-time electronic readout system. Photons are concentrated on the MAPMT photocathode by an optical system that preserves the position information. The ratio between the collection and the photosensitive surfaces is ∼7.5 in our design, larger than in previous applications. A new front-end electronics, based on a modified version of the MAD4 discriminator chip, is being realized to digitize the MAPMT signals. We report about the design of the photodetection system and of the associated electronic readout system, and on the preliminary test beam results.

Published
2006

24. Possible evidence of quantum size effects in x‐ray photoemission spectra of ultrathin Si layers

Author

N. Dibiase, M. Scagliotti, G. Gabetta, Fulvio Parmigiani, and A. Lumachi

Subjects
Materials science, Physics and Astronomy (miscellaneous), Silicon, Physics::Optics, chemistry.chemical_element, Spectral line, Blueshift, X-ray photoelectron spectroscopy, chemistry, Quantum dot, Atomic physics, Thin film, Single crystal, Plasmon
Abstract

This letter reports the experimental evidence of a 2.3 eV blue shift of the plasmon loss lines observed in the x‐ray photoelectron spectra of an ultrathin Si layer equivalent to 1.5×1015 at./cm2 deposited onto a randomly oriented Al2O3 single crystal. The plasmon line shifts, which is roughly proportional to the deposited Si(mass)−2/3, are attributed to quantum confinement effects in agreement with electron energy loss measurements performed on nanosized Si particles.

Published
1995
Full Text
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25. Studies for a fast rich

Author

P. ABBON, M. ALEKSEEV, H. ANGERER, M. APOLLONIO, R. BIRSA, P. BORDALO, F. BRADAMANTE, A. BRESSAN, L. BUSSO, M. CHIOSSO, P. CILIBERTI, M. L. COLANTONI, S. COSTA, S. DALLA TORRE, H. DESCHAMPS, V. DIAZ, N. DIBIASE, V. DUIC, W. EYRICH, D. FASO, A. FERRERO, M. FINGER, H. FISCHER, S. GERASSIMOV, M. GIORGI, B. GOBBO, D. VON HARRACH, F. H. HEINSIUS, S. HORIKAWA, R. JOOSTEN, B. KETZER, K. KOENIGSMANN, V. N. KOLOSOV, I. KONOROV, D. KRAMER, F. KUNNE, A. LEHMAN, A. MAGGIORA, A. MAGNON, A. MARTIN, G. MENON, A. MUTTER, O. NAEHLE, D. NEYRET, F. NERLING, P. PAGANO, S. PANEBIANCO, D. PANZIERI, S. PAUL, J. POLAK, P. REBOURGEARD, P. SCHIAVON, C. SCHILL, W. SCHROEDER, L. SILVA, M. SLUNECKA, F. SOZZI, L. STEIGER, M. SULC, F. TESSAROTTO, and A. TEUFEL

26. Fast photon-detection for COMPASS RICH-1

Author

P. Abbon, M. Alexeev, H. Angerer, R. Birsa, P. Bordalo, F. Bradamante, A. Bressan, M. Chiosso, P. Ciliberti, M. L. Colantoni, T. Dafni, S. Dalla Torre, E. Delagnes, O. Denisov, H. Deschamps, V. Diaz, N. Dibiase, V. Duic, W. Eyrich, A. Ferrero, M. Finger, H. Fisher, S. Gerassimov, M. Giorgi, B. Gobbo, R. Hagemann, D. vonHarrac, F. H. Heinsius, R. Joosten, B. Ketzer, K. Königsmann, V. N. Kolosov, I. Konorov, D. Kramer, F. Kunne, A. Lehmann, S. Levorato, A. Maggiora, A. Magnon, A. Mann, A. Martin, G. Menon, A. Mutter, O. Nähle, D. Neyret, F. Nerling, S. Panebianco, D. Panzieri, S. Paul, G. Pesaro, C. Pizzolotto, J. Polak, P. Rebourgeard, F. Robinet, E. Rocco, P. Schiavon, C. Schill, W. Schoenmeier, W. Schröder, L. Silva, M. Sluneckai, F. Sozzi, L. Steiger, M. Sulc, M. Svec, F. Tessarotto, A. Teufel, and H. Wollny

Subjects
Physics, Optics, business.industry, Compass, business, Photon detection, Particle identification

27. Hartmann test of the COMPASS RICH-1 optical telescopes

Author

Abbon, P., Alekseev, M., Angerer, H., Apollonio, M., Birsa, R., Bordalo, P., Bradamante, F., Andrea Bressan, Busso, L., Chiosso, V. M., Ciliberti, P., Colantoni, M. L., Costa, S., Dibiase, N., Dafni, T., Torre, S. Dalla, Diaz, V., Duic, V., Delagnes, E., Deschamps, H., Eyrich, W., Faso, D., Ferrero, A., Finger, M., Fischer, H., Gerassimov, S., Giorgi, M., Gobbo, B., Hagemann, R., Harrach, D., Heinsius, F. H., Joosten, R., Ketzer, B., Koenigsmann, K., Kolosov, V. N., Konorov, I., Kramer, D., Kunne, F., Levorato, S., Maggiora, A., Magnon, A., Mann, A., Martin, A., Menon, G., Mutter, A., Naehle, O., Neyret, D., Nerling, F., Pagano, P., Paul, S., Panebianco, S., Panzieri, D., Pesaro, G., Pizzolotto, C., Polak, J., Rebourgeard, P., Rocco, E., Robinet, F., Schiavon, P., Schill, C., Schoenmeier, P., Silva, L., Slunecka, M., Steiger, L., Sozzi, F., Sulc, M., Svec, M., Tessarotto, F., Teufel, A., Wollny, H., P., Abbon, T., Dafni, E., Delagne, H., Deschamp, F., Kunne, A., Magnon, D., Neyret, S., Panebianco, P., Rebourgeard, F., Robinet, M., Alekseev, L., Busso, M., Chiosso, S., Costa, N., Dibiase, D., Faso, A., Ferrero, A., Maggiora, H., Angerer, S., Gerasimov, B., Ketzer, I., Konorov, A., Mann, S., Paul, M., Apollonio, R., Birsa, F., Bradamante, Bressan, Andrea, Ciliberti, Piero, S., DALLA TORRE, V., Diaz, V., Duic, M., Giorgi, B., Gobbo, Levorato, Stefano, Martin, Anna, G., Menon, P., Pagano, G., Pesaro, E., Rocco, Schiavon, Paolo, F., Sozzi, F., Tessarotto, P., Bordalo, L., Silva, M. L., Colantoni, D., Panzieri, W., Eyrich, C., Pizzolotto, P., Schonmeier, A., Teufel, M., Finger, M., Slunecka, H., Fischer, R., Hagemann, F. H., Heinsiu, K., Konigsmann, A., Mutter, F., Nerling, C., Schill, H., Wollny, D., VON HARRACH, R., Joosten, O., Nahle, V. N., Kolosov, D., Kramer, J., Polak, L., Steiger, M., Sulc, and M., Svec

Subjects
UV lenses, Hartmann test, Particle Physics - Experiment, COMPASS RICH1
Abstract

The central region of COMPASS RICH-1 has been equipped with a new photon detection system based on MultiAnode PhotoMultiplier Tubes (MAPMT). The Cherenkov photons are focused by an array of 576 fused silica telescopes onto 576 MAPMTs. The quality and positioning of all optical components have been tested by Hartmann method. The validation procedures are described. The quality of the optical concentrators was checked and alignment corrections were made. The upgraded detector showed excellent performances during 2006 data taking.

28. TNF-alpha blockade induce clinical remission in patients affected by polymyalgia rheumatica associated to diabetes mellitus and/or osteoporosis: a seven cases report.

Author

Migliore A, Massafra U, Carloni E, Padalino C, Martin Martin S, Lasaracina F, Dibiase N, Alimonti A, and Granata M

Subjects
Aged, Aged, 80 and over, Antirheumatic Agents therapeutic use, Female, Humans, Infliximab, Polymyalgia Rheumatica complications, Remission Induction, Treatment Outcome, Tumor Necrosis Factor-alpha antagonists & inhibitors, Antibodies, Monoclonal therapeutic use, Diabetes Mellitus, Type 1 complications, Diabetes Mellitus, Type 2 complications, Osteoporosis complications, Polymyalgia Rheumatica drug therapy, Tumor Necrosis Factor-alpha immunology
Abstract

Polymyalgia rheumatica (PMR) is a chronic inflammatory condition of the elderly, characterized by aching and morning stiffness in the cervical region, shoulders and pelvic girdles. A steroid treatment course of 6-24 months is often required, but, due to important side effects, it is troublesome if the PMR patient is also affected by diabetes mellitus (DM) and/or osteoporosis. Aim of our study is to test anti-TNF alpha treatment as a steroid sparing tool in PMR patients affected by DM or osteoporosis. In particular, we hypothesise that TNF alpha blockade can be useful not only in remission maintaining, but also in the induction of clinical remission without corticosteroids in this kind of patients. In a six months follow up, patients had clinical improvement, confirmed by physical medical examination, and a statistically significant reduction in ESR and CRP mean values. Anti-TNF alpha treatment was well tolerated by all patients. These preliminary data suggest than Infliximab can be useful in the treatment of PMR patients, not only for steroid sparing purposes, but also as first line therapy in PMR patients with severe comorbidity, such as diabetes mellitus or osteoporosis.

Published
2005

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