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4 results on '"N. L. Boddington"'

1. Estimating vaccine effectiveness against severe influenza in England and Scotland 2011/2012: applying the screening method to data from intensive care surveillance systems

Author

Helen K. Green, Hongxin Zhao, Jim McMenamin, HL Thomas, N. L. Boddington, Nick Andrews, Richard Pebody, and Arlene Reynolds

Subjects
Adult, Trivalent influenza vaccine, medicine.medical_specialty, Adolescent, Epidemiology, Population, law.invention, Cohort Studies, law, Intensive care, Influenza, Human, medicine, Humans, Child, education, Aged, education.field_of_study, business.industry, Confounding, Infant, Middle Aged, Original Papers, Intensive care unit, Confidence interval, Surgery, Hospitalization, Vaccination, Intensive Care Units, Logistic Models, Infectious Diseases, England, Influenza Vaccines, Child, Preschool, Emergency medicine, business, Sentinel Surveillance, Cohort study
Abstract

SUMMARYMethods for estimating vaccine effectiveness (VE) against severe influenza are not well established. We used the screening method to estimate VE against influenza resulting in intensive care unit (ICU) admission in England and Scotland in 2011/2012. We extracted data on confirmed influenza ICU cases from severe influenza surveillance systems, and obtained their 2011/2012 trivalent influenza vaccine (TIV) status from primary care. We compared case vaccine uptake with population vaccine uptake obtained from routine monitoring systems, adjusting for age group, specific risk group, region and week. Of 60 influenza ICU cases reported, vaccination status was available for 56 (93%). Adjusted VE against ICU admission for those aged ⩾65 years was −10% [95% confidence interval (CI) −207 to 60], consistent with evidence of poor protection from the 2011/2012 TIV in 2011/2012. Adjusted VE for those aged

Published
2013
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2. The United Kingdom public health response to an imported laboratory confirmed case of a novel coronavirus in September 2012

Author

Carlos Carvalho, Nicholas Price, E. Crawley-Boevey, William Newsholme, S. R. Anderson, Colin S Brown, HL Thomas, David Irwin, Helen K. Green, John M Watson, E. Gilgunn-Jones, Cliona M. Rooney, C. Y. W. Tong, Mike Catchpole, N. L. Boddington, E. Aarons, D. Tucker, Hongxin Zhao, C. Langrish, J.P. Crofts, Meera Chand, Richard Pebody, Barry Evans, Alison Bermingham, Kevin E. Brown, and Nick Phin

Subjects
medicine.medical_specialty, Respiratory illness, Epidemiology, business.industry, Public health, Public Health, Environmental and Occupational Health, MEDLINE, Severe disease, medicine.disease_cause, Respiratory isolation, Virology, Intensive care, medicine, Respiratory system, Intensive care medicine, business, Coronavirus
Abstract

On 22 September 2012, a novel coronavirus, very closely related to that from a fatal case in Saudi Arabia three months previously, was detected in a previously well adult transferred to intensive care in London from Qatar with severe respiratory illness. Strict respiratory isolation was instituted. Ten days after last exposure, none of 64 close contacts had developed severe disease, with 13 of 64 reporting mild respiratory symptoms. The novel coronavirus was not detected in 10 of 10 symptomatic contacts tested.

Published
2012
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3. Severe respiratory illness caused by a novel coronavirus, in a patient transferred to the United Kingdom from the Middle East, September 2012

Author

Robin Gopal, E. Aarons, C. Langrish, Katja Hoschler, Richard M. Myers, C. Y. W. Tong, William Newsholme, Helen K. Green, Maria Zambon, Richard Pebody, Nicholas Price, Kevin K. Brown, Meera Chand, Colin S Brown, N. L. Boddington, Christian Drosten, Alison Bermingham, Monica Galiano, and Ron A. M. Fouchier

Subjects
Disease reservoir, medicine.medical_specialty, Pediatrics, Respiratory illness, Middle East, medicine.diagnostic_test, Epidemiology, business.industry, musculoskeletal, neural, and ocular physiology, Public Health, Environmental and Occupational Health, Outbreak, macromolecular substances, medicine.disease_cause, Throat culture, nervous system, Virology, Disease Notification, Medicine, Respiratory system, business, Intensive care medicine, Coronavirus
Abstract

Coronaviruses have the potential to cause severe transmissible human disease, as demonstrated by the severe acute respiratory syndrome (SARS) outbreak of 2003. We describe here the clinical and virological features of a novel coronavirus infection causing severe respiratory illness in a patient transferred to London, United Kingdom, from the Gulf region of the Middle East.

Published
2012
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4. The United Kingdom public health response to an imported laboratory confirmed case of a novel coronavirus in September 2012

Author

R G, Pebody, M A, Chand, H L, Thomas, H K, Green, N L, Boddington, C, Carvalho, C S, Brown, S R, Anderson, C, Rooney, E, Crawley-Boevey, D J, Irwin, E, Aarons, C, Tong, W, Newsholme, N, Price, C, Langrish, D, Tucker, H, Zhao, N, Phin, J, Crofts, A, Bermingham, E, Gilgunn-Jones, K E, Brown, B, Evans, M, Catchpole, and J M, Watson

Subjects
Adult, Coronavirus, Male, Travel, Clinical Laboratory Techniques, London, Public Health Practice, Saudi Arabia, Humans, Coronavirus Infections, Severe Acute Respiratory Syndrome, United Kingdom
Abstract

On 22 September 2012, a novel coronavirus, very closely related to that from a fatal case in Saudi Arabia three months previously, was detected in a previously well adult transferred to intensive care in London from Qatar with severe respiratory illness. Strict respiratory isolation was instituted. Ten days after last exposure, none of 64 close contacts had developed severe disease, with 13 of 64 reporting mild respiratory symptoms. The novel coronavirus was not detected in 10 of 10 symptomatic contacts tested.

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