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Rhinosporidiosis is caused by Rhinosporidium seeberi, a protist of class Mesomycetozoea, which comprises mostly uncultivable aquatic microbes at the animal-fungal boundary. It chiefly affects the mucous membranes of the nose, oropharynx and nasopharynx. It also involves many rare sites and may become disseminated to occur in a generalized form. Soil and water act as a reservoir for the organism. Rhinosporidiosis of the parotid duct is rare and there are very few reported cases in the Indian literature and world-wide. Our case report of a 20-year-old female presenting with facial swelling, the duct cyst was excised and submitted for histopathological examination which confirmed the diagnosis of rhinosporidiosis due to the presence of sporangia and endospores in the wall of the cyst. Keywords: Parotid duct, Rhinosporidiosis, Granulomatous disease, Wet mount

Abstract: Fibroadenoma of axillary breast tissue presents as a palpable mass, cyclic pain in the axilla, and with asthetic concerns. Axillary breast tissue can occur anywhere along the primitive embryonic milk lines, extending from the axilla to the groin, and can present unilaterally or bilaterally. The reported incidence of axillary breast tissue is 0.4%-6% in females. We had two cases of fibroadenoma in the axilla that were diagnosed on rapid on-site evaluation and later confirmed by routine cytology stains in young females. We report the cases for their rarity and high degree of clinical suspicion in the young reproductive age group female. We also emphasize the utility of ROSE in cytopathology., (Copyright © 2023 Copyright: © 2023 Journal of Cancer Research and Therapeutics.)

Background: Oral cancer is the 11 th common cancer in the world and ranks 6 th globally in deaths. The incidence of oral cancer in India accounts for approximately 30%-40% of all cancers., Aims and Objective: The present study was undertaken to evaluate the expression of Vimentin and E-cadherin in different grades of oral epithelial dysplasias (OEDs) and oral squamous cell carcinoma (OSCC)., Materials and Methods: Biopsies/blocks of oral cavity lesions were retrieved from the archives of the department. Normal oral mucosa (5 cases), oral epithelial dysplastic (60 cases) and different grades of OSCC (60 cases) evaluated by hematoxylin and eosin sections. Immunohistochemical analysis was done on the blocks and expression of E-cadherin and Vimentin was recorded., Results: Our study included various grades of OED, OSCC and normal mucosa as control cases. The mean age of OED and OSCC was 49 and 56 years, respectively, with male predominance. Tobacco habit was present in approximately 90% cases, and buccal mucosa was the most commonly involved site in oral cavity with whitish patch and ulceroproliferative lesions being the common clinical presentations respectively. In OED, downregulation and altered localization of e-cadherin (81.6%) and increased expression of vimentin (52.3%) along with their concurrent increase in the stroma represent epithelial mesenchymal transition. In OSCC, reduction in expression (<50%) for e-cadherin (56.6%) with altered localization for e-cadherin was seen in 88.3% of OSCC along with neoexpression of vimentin in the epithelial cells was seen in 68.3% suggestive of mesenchymal phenotypic modification ( P = 0.05)., Conclusion: It is very crucial to evaluate the invasiveness of dysplasia and tumor with specific molecular biomarker that may help in early prediction of malignancy and also guide in deciding best treatment strategy for established cases of malignancy., Competing Interests: There are no conflicts of interest., (Copyright: © 2022 Journal of Oral and Maxillofacial Pathology.)

Background: Cysticercosis is a zoonotic disease. It is caused by the larval form of the pork tapeworm Taenia solium. This disease is a public health problem in a country like India, but its incidence is underestimated. With the advent of fine needle aspiration cytology with rapid on-site evaluation, early detection of this disease is possible, especially when the lesion is in anatomically approachable superficial locations., Case Report: We had four cases of cysticercosis diagnosed by fine needle aspiration cytology with on-site evaluation using toluidine blue stain, followed by Giemsa and Papanicolaou stain. Our cases included three Hindu male patients of age 30 years, 23 years, 17 years and an 26 year old Hindu female., Conclusion: Fine needle aspiration cytology diagnosis of cysticercosis can be easily made provided the reporting cytologist is aware of the morphological criteria. Rapid on-site evaluation can further help in taking additional material and caution during staining process.