Search

Your search keyword '"N.N. Khanna"' showing total 23 results
Start Over Author "N.N. Khanna"
23 results on '"N.N. Khanna"'

1. Arrhythmia and Time of Day in Maintenance Hemodialysis: Secondary Analysis of the Monitoring in Dialysis Study

Author

Qandeel H. Soomro, Bruce A. Koplan, Alexandru I. Costea, Prabir Roy-Chaudhury, James A. Tumlin, Vijay Kher, Don E. Williamson, Saurabh Pokhariyal, Candace K. McClure, David M. Charytan, Don Williamson, James Tumlin, Vikranth Reddy, Kowdle Chandrasekhar Prakash, David Charytan, Suresh Chandra Tiwari, Amber Podoll, Sanjeev Jasuja, G. Leslie Walters, Kraig Wangsnes, Alexandru Costea, Selcuk Tombul, Balbir Singh, Brajesh Mishra, Sachin Yalagudri, Abhijeet Shelke, Calambur Narasimhan, A.M. Karthigesan, Abraham Oomman, K.P. Pramod Kumar, Bruce Koplan, Upendra Kaul, Tapan Ghose, Ripen Gupta, Arvind Sethi, Nikhil Kumar, Ramesh Hariharan, Rajnish Sardana, Arif Wahab, N.N. Khanna, Mark Smith, Suresh Kamath, Claude Galphin, Puneet Sodhi, Rajsekara Chakravarthy, Subba Rao Budithi, Finnian McCausland, Sanjeev Gulati, Munawer Dijoo, Upendra Singh, Salil Jain, Vishal Saxena, Gaurav Sagar, Rachel Fissell, Robert Foley, Charles A. Herzog, Peter McCullough, John D. Rogers, Peter Zimetbaum, Manish Assar, Mark Kremers, and Wolfgang C. Winkelmayer

Subjects
Arrhythmia, atrial fibrillation, bradycardia, circadian rhythm, dialysis, end-stage kidney disease, Diseases of the genitourinary system. Urology, RC870-923
Abstract

Rationale & Objective: The incidence of arrhythmia varies by time of day. How this affects individuals on maintenance dialysis is uncertain. Our objective was to quantify the relationship of arrhythmia with the time of day and timing of dialysis. Study Design: Secondary analysis of the Monitoring in Dialysis study, a multicenter prospective cohort study. Settings & Participants: Loop recorders were implanted for continuous cardiac monitoring in 66 participants on maintenance dialysis with a follow up of 6 months. Exposure: Time of day based on 6-hour intervals. Outcomes: Event rates of clinically significant arrhythmia. Analytical Approach: Negative binomial mixed effects regression models for repeated measures were used to evaluate data from the Monitoring in Dialysis study for differences in diurnal patterns of clinically significant arrhythmia among those with end-stage kidney disease with heart failure and end-stage kidney disease alone. We additionally analyzed rates according to presence of heart failure, time of dialysis shift, and dialysis versus nondialysis day. Results: Rates of clinically significant arrhythmia peaked between 12:00 AM and 5:59 AM and were more than 1.5-fold as frequent during this interval than the rest of the day. In contrast, variations in atrial fibrillation peaked between 6:00 AM and 11:59 AM, but variations across the day were qualitatively small. Clinically significant arrhythmia occurred at numerically higher rate in individuals with end-stage kidney disease and heart failure (5.9 events/mo; 95% CI, 1.3-26.8) than those without heart failure (4.0 events/mo; 95% CI, 0.9-17.9). Although differences in overall rate were not significant, their periodicity was significantly different (P

Published
2024
Full Text
View/download PDF

2. Implantable Loop Recorder Monitoring and the Incidence of Previously Unrecognized Atrial Fibrillation in Patients on Hemodialysis

Author

Bruce A. Koplan, Wolfgang C. Winkelmayer, Alexandru I. Costea, Prabir Roy-Chaudhury, James A. Tumlin, Vijay Kher, Don E. Williamson, Saurabh Pokhariyal, David M. Charytan, Don Williamson, MD, Prabir Roy-Chaudhury, MD, James Tumlin, MD, Vijay Kher, MD, Vikranth Reddy, MD, Kowdle Chandrasekhar Prakash, MD, David Charytan, MD MSc, Suresh Chandra Tiwari, MD, Saurabh Pokhariyal, MD, Amber Podoll, MD, Sanjeev Jasuja, MD, G. Leslie Walters, MD, Kraig Wangsnes, MD, Alexandru Costea, MD, Selcuk Tombul, MD, Balbir Singh, MD, Brajesh Mishra, MD, Sachin Yalagudri, MD, Abhijeet Shelke, MD, Calambur Narasimhan, MD, A.M. Karthigesan, MD, Abraham Oomman, MD, K P Pramod Kumar, MD, Bruce Koplan, MD, Upendra Kaul, MD, Tapan Ghose, MD, Ripen Gupta, MD, Arvind Sethi, MD, Nikhil Kumar, MD, Ramesh Hariharan, MD, Rajnish Sardana, MD, Arif Wahab, MD, N.N. Khanna, MD, Mark Smith, MD, Suresh Kamath, MD, Claude Galphin, MD, Puneet Sodhi, MD, Rajsekara Chakravarthy, MD, Subba Rao Budithi, MD, Finnian McCausland, MB, MMSc, Sanjeev Gulati, MD, Munawer Dijoo, MD, Upendra Singh, MD, Salil Jain, MD, Vishal Saxena, MD, Gaurav Sagar, MD, David Charytan, MD, MSc, Rachel Fissell, MD, Robert Foley, MD, Charles A. Herzog, MD, Peter A. McCullough, MD, John D. Rogers, MD, James A. Tumlin, MD, Peter Zimetbaum, MD, Manish Assar, MD, Mark Kremers, MD, and Wolfgang C. Winkelmayer, MD, ScD

Subjects
arrhythmias, atrial fibrillation, hemodialysis, kidney failure, end stage kidney diseae (ESKD), implantable loop recorder, Diseases of the genitourinary system. Urology, RC870-923
Abstract

Introduction: Atrial fibrillation (AF) is common in patients with kidney failure on hemodialysis (KF-HD). We determined both AF incidence and burden in patients with KF-HD using implantable loop recorder (ILR) monitoring. Methods: Patients with KF-HD were enrolled and received an ILR. In 6 monitoring months, the incidence of AF events lasting ≥6 minutes was captured. Demographic, clinical, and dialysis characteristics were collected, and associations with incident AF were estimated using negative binomial regression models and expressed as incidence rate ratios and 95% CIs. Results: We enrolled 66 patients with KF-HD (mean age = 56 years, 70% male); 59 (90%) were without previously diagnosed AF. AF lasting ≥6 minutes was detected in 18 of 59 subjects (31%) without previously diagnosed AF and in 5 of 7 subjects (71%) with a previous AF diagnosis. Among the 23 with detected AF, episodes were present on 16% of patient days. Although 14 of 23 patients (61%) had AF on 2.5 vs. 2.5 mEq/l: incidence rate ratio = 0.62; 95% CI, 0.48–0.80) was associated with lower AF risk whereas higher dialysate bicarbonate concentrations (>35 vs. 35 mEq/l: incidence rate ratio = 3.18; 95% CI, 1.13–8.94) were associated with higher AF risk. Conclusion: New AF was detected in approximately one-third of patients with KF-HD. AF affects a substantial proportion of patient days and may be an underappreciated cause of stroke in KF-HD.

Published
2022
Full Text
View/download PDF

3. Cardiological society of India document on safety measure during echo evaluation of cardiovascular disease in the time of COVID-19

Author

Rakesh Gupta, Mrinal Kanti Das, P.P. Mohanan, Pradip K. Deb, S.K. Parashar, H.K. Chopra, Sameer Shrivastava, Santanu Guha, Kewal C. Goswami, Rakesh Yadav, R. Alagesan, V. Amuthan, M. Bansal, R.N. Chakraborty, N. Chakraborti, S. Chandra, A. Chatterjee, D. Chatterjee, S.S. Chatterjee, A.L. Dutta, A. De, A. Garg, V.K. Garg, A. Goyal, N.K. Goyal, S.C. Govind, V.K. Gupta, Pradeep K. Hasija, A. Jabir, P. Jain, V. Jain, P.B. Jayagopal, R.R. Kasliwal, V.K. Katyal, P.G. Kerkar, Amal Kumar Khan, N.N. Khanna, M. Mandal, B. Majumder, S.S. Mishra, C.B. Meena, N. Naik, V.S. Narain, A.K. Pancholia, L.A. Pathak, C.K. Ponde, K. Raghu, S. Ray, D. Roy, D. Sarma, S. Shanmugasundarum, B.P. Singh, S. Tyagi, G. Vijayaraghavan, G.S. Wander, Harsh Wardhan, and N.C. Nanda

Subjects
COVID -19, Cardiovascular evaluation, Safety measures, Echocardiography, Cardiological Society of India, Surgery, RD1-811, Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract

An echocardiographic investigation is one of the key modalities of diagnosis in cardiology. There has been a rising presence of cardiological comorbidities in patients positive for COVID-19. Hence, it is becoming extremely essential to look into the correct safety precautions, healthcare professionals must take while conducting an echo investigation. The decision matrix formulated for conducting an echocardiographic evaluation is based on presence or absence of cardiological comorbidity vis-à-vis positive, suspected or negative for COVID-19. The safety measures have been constructed keeping in mind the current safety precautions by WHO, CDC and MoHFW, India.

Published
2020
Full Text
View/download PDF

4. Cardiological society of India position statement on COVID-19 and heart failure

Author

S. Harikrishnan, P.P. Mohanan, V.K. Chopra, Roy Ambuj, G. Sanjay, Manish Bansal, R.N. Chakraborty, Sharad Chandra, S.S. Chattarjee, H.K. Chopra, Cibu Mathew, P.K. Deb, A. Goyal, K.C. Goswami, R. Gupta, S. Guha, V. Gupta, P.K. Hasija, Harsh Wardhan, A. Jabir, P.B. Jayagopal, D. Kahali, V.K. Katyal, P.G. Kerkar, N.N. Khanna, B. Majumder, M. Mandal, C.B. Meena, N. Naik, V.K. Narain, L.A. Pathak, S. Ray, D. Roy, S.N. Routray, D. Sarma, S. Shanmugasundaram, B.P. Singh, S.K. Tyagi, K. Venugopal, G.S. Wander, Rakesh Yadav, and M.K. Das

Subjects
Coronavirus, COVID-19, Heart failure, Cardiac injury, Mortality, Cardiovascular disease, Surgery, RD1-811, Diseases of the circulatory (Cardiovascular) system, RC666-701
Published
2020
Full Text
View/download PDF

5. Cardiological Society of India: Document on acute MI care during COVID-19

Author

P.G. Kerkar, N. Naik, T. Alexander, V.K. Bahl, R.N. Chakraborty, S.S. Chatterjee, H.K. Chopra, S.I. Dani, P.K. Deb, K.C. Goswami, S. Guha, R. Gupta, V. Gupta, P.K. Hasija, P.B. Jayagopal, G. Justin Paul, D. Kahali, V.K. Katyal, N.N. Khanna, M. Mandal, S.S. Mishra, P.P. Mohanan, A. Mullasari, S. Mehta, A.K. Pancholia, S. Ray, D. Roy, S. Shanmugasundarm, S. Sharma, B.P. Singh, S. Tewari, S.K. Tyagi, K.N. Venugopal, G.S. Wander, R. Yadav, and M.K. Das

Subjects
Corona virus, ST-Elevation MI, Acute coronary syndrome, Coronary thrombosis, Surgery, RD1-811, Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract

The unprecedented and rapidly spreading Coronavirus Disease-19 (COVID-19) pandemic has challenged public health care systems globally. Based on worldwide experience, India has initiated a nationwide lockdown to prevent the exponential surge of cases. During COVID-19, management of cardiovascular emergencies like acute Myocardial Infarction (MI) may be compromised. Cardiological Society of India (CSI) has ventured in this moment of crisis to evolve a consensus document for care of acute MI. However, this care should be individualized, based on local expertise and governmental advisories.

Published
2020
Full Text
View/download PDF

8. Cardiological Society of India

Author

Santanu Guha, Rishi Sethi, Saumitra Ray, Vinay K. Bahl, S. Shanmugasundaram, Prafula Kerkar, Sivasubramanian Ramakrishnan, Rakesh Yadav, Gaurav Chaudhary, Aditya Kapoor, Ajay Mahajan, Ajay Kumar Sinha, Ajit Mullasari, Akshyaya Pradhan, Amal Kumar Banerjee, B.P. Singh, J. Balachander, Brian Pinto, C.N. Manjunath, Chandrashekhar Makhale, Debabrata Roy, Dhiman Kahali, Geevar Zachariah, G.S. Wander, H.C. Kalita, H.K. Chopra, A. Jabir, JagMohan Tharakan, Justin Paul, K. Venogopal, K.B. Baksi, Kajal Ganguly, Kewal C. Goswami, M. Somasundaram, M.K. Chhetri, M.S. Hiremath, M.S. Ravi, Mrinal Kanti Das, N.N. Khanna, P.B. Jayagopal, P.K. Asokan, P.K. Deb, P.P. Mohanan, Praveen Chandra, (Col.) R. Girish, O. Rabindra Nath, Rakesh Gupta, C. Raghu, Sameer Dani, Sandeep Bansal, Sanjay Tyagi, Satyanarayan Routray, Satyendra Tewari, Sarat Chandra, Shishu Shankar Mishra, Sibananda Datta, S.S. Chaterjee, Soumitra Kumar, Soura Mookerjee, Suma M. Victor, Sundeep Mishra, Thomas Alexander, Umesh Chandra Samal, and Vijay Trehan

Subjects
Surgery, RD1-811, Diseases of the circulatory (Cardiovascular) system, RC666-701
Published
2017
Full Text
View/download PDF

16. Primary outcomes of the Monitoring in Dialysis Study indicate that clinically significant arrhythmias are common in hemodialysis patients and related to dialytic cycle

Author

Prabir Roy-Chaudhury, Jim A. Tumlin, Bruce A. Koplan, Alexandru I. Costea, Vijay Kher, Don Williamson, Saurabh Pokhariyal, David M. Charytan, James Tumlin, Vikranth Reddy, Kowdle Chandrasekhar Prakash, David Charytan, Suresh Chandra Tiwari, Amber Podoll, Sanjeev Jasuja, G. Leslie Walters, Kraig Wangsnes, Alexandru Costea, Selcuk Tombul, Balbir Singh, Brajesh Mishra, Sachin Yalagudri, Abhijeet Shelke, Calambur Narasimhan, A.M. Karthigesan, Abraham Oomman, K.P. Pramod Kumar, Bruce Koplan, Upendra Kaul, Tapan Ghose, Ripen Gupta, Arvind Sethi, Nikhil Kumar, Ramesh Hariharan, Rajnish Sardana, Arif Wahab, N.N. Khanna, Mark Smith, Suresh Kamath, Claude Galphin, Puneet Sodhi, Rajsekara Chakravarthy, Subba Rao Budithi, Finnian McCausland, Sanjeev Gulati, Munawer Dijoo, Upendra Singh, Salil Jain, Vishal Saxena, Gaurav Sagar, Rachel Fissell, Robert Foley, Charles A. Herzog, Peter McCullough, John D. Rogers, James A. Tumlin, Peter Zimetbaum, Manish Assar, Mark Kremers, and Wolfgang C. Winkelmayer

Subjects
Adult, Male, Bradycardia, medicine.medical_specialty, Time Factors, medicine.medical_treatment, 030232 urology & nephrology, India, 030204 cardiovascular system & hematology, Ventricular tachycardia, Risk Assessment, Sudden death, End stage renal disease, 03 medical and health sciences, 0302 clinical medicine, Heart Rate, Renal Dialysis, Risk Factors, Dialysis Solutions, Internal medicine, medicine, Humans, Prospective Studies, cardiovascular diseases, Asystole, Dialysis, Aged, business.industry, Incidence, Sodium, Arrhythmias, Cardiac, Atrial fibrillation, Middle Aged, medicine.disease, United States, Death, Sudden, Cardiac, Treatment Outcome, Nephrology, cardiovascular system, Cardiology, Kidney Failure, Chronic, Calcium, Female, Hemodialysis, medicine.symptom, business, Biomarkers
Abstract

Sudden death is one of the more frequent causes of death for hemodialysis patients, but the underlying mechanisms, contribution of arrhythmia, and associations with serum chemistries or the dialysis procedure are incompletely understood. To study this, implantable loop recorders were utilized for continuous cardiac rhythm monitoring to detect clinically significant arrhythmias including sustained ventricular tachycardia, bradycardia, asystole, or symptomatic arrhythmias in hemodialysis patients over six months. Serum chemistries were tested pre- and post-dialysis at least weekly. Dialysis procedure data were collected at every session. Associations with clinically significant arrhythmias were assessed using negative binomial regression modeling. Sixty-six patients were implanted and 1678 events were recorded in 44 patients. The majority were bradycardias (1461), with 14 episodes of asystole and only one of sustained ventricular tachycardia. Atrial fibrillation, although not defined as clinically significant arrhythmias, was detected in 41% of patients. With thrice-weekly dialysis, the rate was highest during the first dialysis session of the week and was increased during the last 12 hours of each inter-dialytic interval, particularly the long interval. Among serum and dialytic parameters, only higher pre-dialysis serum sodium and dialysate calcium over 2.5 mEq/L were independently associated with clinically significant arrhythmias. Thus, clinically significant arrhythmias are common in hemodialysis patients, and bradycardia and asystole rather than ventricular tachycardia may be key causes of sudden death in hemodialysis patients. Associations with the temporal pattern of dialysis suggest that modification of current dialysis practices could reduce the incidence of sudden death.

Published
2018
Full Text
View/download PDF

17. Interventional management of hypertension

Author

N.N. Khanna and Suparna Rao

Subjects
03 medical and health sciences, medicine.medical_specialty, 0302 clinical medicine, business.industry, Medicine, Interventional management, 030212 general & internal medicine, 030204 cardiovascular system & hematology, business, Intensive care medicine
Published
2017
Full Text
View/download PDF

18. Catheter directed thrombolytic therapy and percutaneous thrombectomy

Author

Suparna Rao and N.N. Khanna

Subjects
medicine.medical_specialty, business.industry, Cardiogenic shock, medicine.medical_treatment, Thrombolysis, medicine.disease, May–Thurner syndrome, Surgery, Pulmonary embolism, Catheter, Internal medicine, medicine.artery, Pulmonary artery, medicine, Cardiology, Thrombus, business, Post-thrombotic syndrome
Abstract

40% of DVTs occur in the femoral and iliac veins and have a high risk of pulmonary thromboembolism and Post Thrombotic Syndrome (PTS), which can be avoided by timely interventional management. Catheter Directed Thrombolytic Therapy (CDTT) and Pharmacomechanical Catheter-Directed Thrombolysis (PCDT), (combination of CDTT with percutaneous mechanical thrombectomy) techniques enhance the efficiency and rate of thrombus removal. It also uncovers the May Thurner syndrome in many cases. Massive Pulmonary Embolism (PE) is associated with high morbidity and mortality due to thrombotic occlusion of main pulmonary artery and/or both major pulmonary arteries leading to severe hypoxemia, pulmonary artery hypertension and cardiogenic shock. Till now, open surgical pulmonary endarterectomy was the only option for prompt restoration of flow in major pulmonary arteries but carried a high mortality in hemodynamically unstable patients. Catheter based pulmonary thromboaspiration and intrapulmonary thrombolysis can be used. We present our experience in 45 consecutive patients of massive PE presenting with cardiogenic shock.

Published
2017
Full Text
View/download PDF

20. Electrical burns: a review of 80 cases

Author

Meera Dutta Chowdary, N.N. Khanna, J.K. Sinha, F.M. Tripathi, and V. Bhattacharya

Subjects
medicine.medical_specialty, business.industry, Incidence (epidemiology), Human factors and ergonomics, Poison control, General Medicine, Critical Care and Intensive Care Medicine, medicine.disease, Suicide prevention, Occupational safety and health, Acquired immunodeficiency syndrome (AIDS), Emergency medicine, Injury prevention, Emergency Medicine, medicine, Surgery, Rural electrification, Medical emergency, business
Abstract

Eighty cases of electrical burns admitted over a period of 12 years from 1965 have been analysed with respect to age and sex distribution, incidence, site of burn, mode of electrical contact, management and complications. Mortality in the present review was 3–75 per cent. It is felt that before undertaking massive rural electrification in a developing community, the hazards of electricity should be explained by various means, including the use of audio-visual aids, since the majority of these accidents are avoidable and occur in the younger age groups.

Published
1978
Full Text
View/download PDF

21. Repair of distal penile hypospadias—A new technique

Author

N.N. Khanna

Subjects
Male, Hypospadias, business.industry, Penile skin, Distal penile hypospadias, Skin Transplantation, Anatomy, Transplantation, Autologous, medicine.anatomical_structure, Urethra, Otorhinolaryngology, Methods, medicine, Humans, Surgery, business, Penis
Abstract

Summary A new operation for the repair of distal penile hypospadias has been described in which the whole of the penile skin is rotated through 180° to provide cover to the shaft of the penis and the reconstructed urethra.

Published
1971
Full Text
View/download PDF

22. Plasma catecholamines in thermal burns

Author

N.N. Khanna, K.N. Udupa, F.M. Tripathi, J.K. Sinha, S. Guha, and J.P.N. Chansoria

Subjects
business.industry, Anesthesia, Emergency Medicine, Medicine, Surgery, In patient, General Medicine, Plasma catecholamine level, Critical Care and Intensive Care Medicine, business
Abstract

This present study is based on the observations on plasma catecholamines in 35 cases of thermal burns of varying severity. In all the groups, there was an initial rise in plasma catecholamine level followed by a gradual decline except in patients of burn index more than 26 who died and in whom values were persistently high. Results were also compared with that of normal controls and patients with planned and unplanned surgical trauma.

Published
1981
Full Text
View/download PDF

23. Gangrene of the scrotum: A series of 20 cases

Author

V. Venkateshwarlu, J.K. Sinha, F.M. Tripathi, and N.N. Khanna

Subjects
Adult, Male, Gangrene, medicine.medical_specialty, business.industry, Skin Transplantation, Middle Aged, medicine.disease, Transplantation, Autologous, Surgery, medicine.anatomical_structure, Otorhinolaryngology, Streptococcal Infections, Scrotum, medicine, Humans, Genital Diseases, Male, business, Aged
Published
1978
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results