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5 results on '"NAKASAWA, Takashi"'

2. Critical regions for assembly of vertebrate nonmuscle myosin II

Author

Nakasawa, Takashi, Takahashi, Masayuki, Matsuzawa, Fumiko, Aikawa, Seiichi, Togashi, Yuki, Saitoh, Takayuki, Yamagishi, Akihiko, and Yazawa, Michio

Subjects
Vertebrates -- Research, Myosin -- Research, Biological sciences, Chemistry
Abstract

An assessment of the solubility of a series of truncated recombinant rod fragments of nonmuscle myosin IIB at various concentrations of NaCl was done to estimate the critical region for filament formation of vertebrate nonmuscle myosin II. Details of the two major electrostatic interactions that are essential for filament formation of nonmuscle myosin II are discussed.

Published
2005

3. Functions of Nonmuscle Myosin II Isoforms

Author

TAKAHASHI, Masayuki, NAKASAWA, Takashi, SATO, Masaaki, HIRATA, Naoya, MITSUHASHI, Mariko, and YAZAWA, Michio

Subjects
myosin II, filament, cell migration, phosphorylation, subcellular localization, nonmuscle cells
Abstract

非筋細胞ミオシンIIは, 運動を可能にする構造体(収縮装置)を, 必要なときに必要な場所で形成することで, さまざまな細胞の運動過程にかかわっている.本稿では, 最近我々が提唱したミオシンIIのフィラメント形成の分子機構モデルを紹介し, さらに細胞移動時におけるミオシンIIの各アイソフォームの機能について議論する.

Published
2006

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