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2. Proceedings from the Consensus Conference on Trauma Patient-Reported Outcome Measures

Author

Amtmann, Dagmar, Bixby, Pam, Brighton, Brian, Burstin, Helen, Burns, Chris, Caldwell, Michelle, Chaney, Eric, Chung, Kevin, Cipolle, Mark, deRoon-Cassine, Terri, Dicker, Rochelle, Fallat, Mary E., Gabbe, Belinda, Gfeller, Bob, Jr., Gioia, Gerard, Haut, Elliott, Hendrix, Jason, Hoeft, Chris, Hotz, Heidi, Keavany, Kathleen, Levy-Carrick, Nomi, Manley, Geoffrey T., Michetti, Christopher, Miller, Anna, Miller, Cate, Morris, David S., Naik-Mathuria, Bindi J., Neal, Melanie, Patel, Bhavin, Newgard, Craig, Nitzschke, Stephanie, Okonkwo, David O., Polk, Travis, Price, Michelle, Rivara, Fred, Sochor, Mark, Stein, Deb, Subacius, Haris, Taylor, H. Gerry, Thomas, William, III, Wagner, Amy, Winfield, Rob, Zatzick, Douglas F., Zielinski, Martin D., Sakran, Joseph V., Ezzeddine, Hiba, Schwab, C. William, Bonne, Stephanie, Brasel, Karen J., Burd, Randall S., Cuschieri, Joseph, Ficke, James, Gaines, Barbara A., Giacino, Joseph T., Gibran, Nicole S., Haider, Adil, Hall, Erin C., Herrera-Escobar, Juan P., Joseph, Bellal, Kao, Lillian, Kurowski, Brad G., Livingston, David, Mandell, Samuel P., Nehra, Deepika, Sarani, Babak, Seamon, Mark, Yonclas, Peter, Zarzaur, Ben, Stewart, Ronald, Bulger, Eileen, and Nathens, Avery B.

Published
2020
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3. Heart failure supported by veno-arterial extracorporeal membrane oxygenation (ECMO): a systematic review of pre-clinical models

Author

Sacha Rozencwajg, Silver Heinsar, Jacky Suen, Gianluigi Li Bassi, Maximilian Malfertheiner, Leen Vercaemst, Lars Mikael Broman, Matthieu Schmidt, Alain Combes, Indrek Rätsep, John F. Fraser, Jonathan E. Millar, and on behalf of the European Extracorporeal Life Support Organisation (EuroELSO) Innovations Workgroup & the National Health Medical Research Council Australia Centre of Research Excellence for Advanced Cardio-respiratory Therapies Improving Organ Support (NHMRC CREACTIONS)

Subjects
Heart failure, Extracorporeal membrane oxygenation, Animal models, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9
Abstract

Abstract Objectives Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is increasingly being used to treat patients with refractory severe heart failure. Large animal models are developed to help understand physiology and build translational research projects. In order to better understand those experimental models, we conducted a systematic literature review of animal models combining heart failure and VA-ECMO. Studies selection A systematic review was performed using Medline via PubMed, EMBASE, and Web of Science, from January 1996 to January 2019. Animal models combining experimental acute heart failure and ECMO were included. Clinical studies, abstracts, and studies not employing VA-ECMO were excluded. Data extraction Following variables were extracted, relating to four key features: (1) study design, (2) animals and their peri-experimental care, (3) heart failure models and characteristics, and (4) ECMO characteristics and management. Results Nineteen models of heart failure and VA-ECMO were included in this review. All were performed in large animals, the majority (n = 13) in pigs. Acute myocardial infarction (n = 11) with left anterior descending coronary ligation (n = 9) was the commonest mean of inducing heart failure. Most models employed peripheral VA-ECMO (n = 14) with limited reporting. Conclusion Among models that combined severe heart failure and VA-ECMO, there is a large heterogeneity in both design and reporting, as well as methods employed for heart failure. There is a need for standardization of reporting and minimum dataset to ensure translational research achieve high-quality standards.

Published
2020
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4. Extracorporeal membrane oxygenation (ECMO) and the acute respiratory distress syndrome (ARDS): a systematic review of pre-clinical models

Author

Jonathan E. Millar, Nicole Bartnikowski, Viktor von Bahr, Maximilian V. Malfertheiner, Nchafatso G. Obonyo, Mirko Belliato, Jacky Y. Suen, Alain Combes, Daniel F. McAuley, Roberto Lorusso, John F. Fraser, on behalf of the European Extracorporeal Life Support Organisation (EuroELSO) Innovations Workgroup, and the National Health Medical Research Council Australia Centre of Research Excellence for Advanced Cardio-respiratory Therapies Improving Organ Support (NHMRC CREACTIONS)

Subjects
Extracorporeal membrane oxygenation, Acute respiratory distress syndrome, Animal models, Pre-clinical models, Systematic review, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9
Abstract

Abstract Objectives Extracorporeal membrane oxygenation (ECMO) is an increasingly accepted means of supporting those with severe acute respiratory distress syndrome (ARDS). Given the high mortality associated with ARDS, numerous animal models have been developed to support translational research. Where ARDS is combined with ECMO, models are less well characterized. Therefore, we conducted a systematic literature review of animal models combining features of experimental ARDS with ECMO to better understand this situation. Data sources MEDLINE and Embase were searched between January 1996 and December 2018. Study selection Inclusion criteria: animal models combining features of experimental ARDS with ECMO. Exclusion criteria: clinical studies, abstracts, studies in which the model of ARDS and ECMO has been reported previously, and studies not employing veno-venous, veno-arterial, or central ECMO. Data extraction Data were extracted to fully characterize models. Variables related to four key features: (1) study design, (2) animals and their peri-experimental care, (3) models of ARDS and mechanical ventilation, and (4) ECMO and its intra-experimental management. Data synthesis Seventeen models of ARDS and ECMO were identified. Twelve were published after 2009. All were performed in large animals, the majority (n = 10) in pigs. The median number of animals included in each study was 17 (12–24), with a median study duration of 8 h (5–24). Oleic acid infusion was the commonest means of inducing ARDS. Most models employed peripheral veno-venous ECMO (n = 12). The reporting of supportive measures and the practice of mechanical ventilation were highly variable. Descriptions of ECMO equipment and its management were more complete. Conclusion A limited number of models combine the features of experimental ARDS with ECMO. Among those that do, there is significant heterogeneity in both design and reporting. There is a need to standardize the reporting of pre-clinical studies in this area and to develop best practice in their design.

Published
2019
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6. Structural brain alterations associated with suicidal thoughts and behaviors in young people: results from 21 international studies from the ENIGMA Suicidal Thoughts and Behaviours consortium

Author

Universidad de Sevilla. Departamento de Psiquiatría, American Foundation for Suicide Prevention (AFSP), Australian National Health and Medical Research Council (NHMRC), Biotechnology Research Center, Brain and Behavior Research Foundation, CJ Martin Fellowship (NHMRC), Deborah E. Powell Center for Women's Health Seed Grant, University of Minnesota, European Commission (EC). Fondo Europeo de Desarrollo Regional (FEDER) /Fondo Social Europeo "Invertir en tu futuro", Famous Doctors Project of Yunnan Province Plan, For the Love of Travis Foundation, Fundacion Instituto de Investigacion Marques de Valdecilla, Deutsche Forschungsgemeinschaft / German Research Foundation (DFG), Good Talk, Instituto de Salud Carlos III, Interdisziplinares Zentrum fur Klinische Forschung, UKJ, International Bipolar Foundation, Ministerio italiano de Salud, J. Jacobson Fund., Janette Mary O'Neil Research Fellowship, Keith Pettigrew Family Bequest, Klingenstein Third Generation Foundation, Lansdowne Foundation, Medical Faculty Munster, Innovative Medizinische Forschung, Medical Leader Foundation of Yunnan Province, Minnesota Medical Foundation, MQ Brighter Futures, MQ Brighter Futures Award, National Alliance for Research on Schizophrenia and Depression, National Center for Advancing Translational Sciences (CTSI), National Institutes of Health, National Center for Complementary and Integrative Health (NCCIH), National Institute of Mental Health (NIMH), NHMRC Career Development Fellowships, NIAAA, Program "Investissements d'avenir", Ray and Dagmar Dolby Family Fund., Social Safety and Resilience program of Leiden University, Stanford Center for Cognitive and Neurobiological Imaging, Stanford Maternal Child Health Research Institute, U.S. National Institute of Mental Health, UCSF Research Evaluation and Allocation Committee (REAC), University of Minnesota, Women's Health Research at Yale, van Velzen, Laura S., Dauvermann, Maria R., Colic, Lejla, Villa, Luca M., Savage, Hannah S., Toenders, Yara J., Crespo Facorro, Benedicto, Schmaal, Lianne, Universidad de Sevilla. Departamento de Psiquiatría, American Foundation for Suicide Prevention (AFSP), Australian National Health and Medical Research Council (NHMRC), Biotechnology Research Center, Brain and Behavior Research Foundation, CJ Martin Fellowship (NHMRC), Deborah E. Powell Center for Women's Health Seed Grant, University of Minnesota, European Commission (EC). Fondo Europeo de Desarrollo Regional (FEDER) /Fondo Social Europeo "Invertir en tu futuro", Famous Doctors Project of Yunnan Province Plan, For the Love of Travis Foundation, Fundacion Instituto de Investigacion Marques de Valdecilla, Deutsche Forschungsgemeinschaft / German Research Foundation (DFG), Good Talk, Instituto de Salud Carlos III, Interdisziplinares Zentrum fur Klinische Forschung, UKJ, International Bipolar Foundation, Ministerio italiano de Salud, J. Jacobson Fund., Janette Mary O'Neil Research Fellowship, Keith Pettigrew Family Bequest, Klingenstein Third Generation Foundation, Lansdowne Foundation, Medical Faculty Munster, Innovative Medizinische Forschung, Medical Leader Foundation of Yunnan Province, Minnesota Medical Foundation, MQ Brighter Futures, MQ Brighter Futures Award, National Alliance for Research on Schizophrenia and Depression, National Center for Advancing Translational Sciences (CTSI), National Institutes of Health, National Center for Complementary and Integrative Health (NCCIH), National Institute of Mental Health (NIMH), NHMRC Career Development Fellowships, NIAAA, Program "Investissements d'avenir", Ray and Dagmar Dolby Family Fund., Social Safety and Resilience program of Leiden University, Stanford Center for Cognitive and Neurobiological Imaging, Stanford Maternal Child Health Research Institute, U.S. National Institute of Mental Health, UCSF Research Evaluation and Allocation Committee (REAC), University of Minnesota, Women's Health Research at Yale, van Velzen, Laura S., Dauvermann, Maria R., Colic, Lejla, Villa, Luca M., Savage, Hannah S., Toenders, Yara J., Crespo Facorro, Benedicto, and Schmaal, Lianne

Abstract

Identifying brain alterations associated with suicidal thoughts and behaviors (STBs) in young people is critical to understanding their development and improving early intervention and prevention. The ENIGMA Suicidal Thoughts and Behaviours (ENIGMA-STB) consortium analyzed neuroimaging data harmonized across sites to examine brain morphology associated with STBs in youth. We performed analyses in three separate stages, in samples ranging from most to least homogeneous in terms of suicide assessment instrument and mental disorder. First, in a sample of 577 young people with mood disorders, in which STBs were assessed with the Columbia Suicide Severity Rating Scale (C-SSRS). Second, in a sample of young people with mood disorders, in which STB were assessed using different instruments, MRI metrics were compared among healthy controls without STBs (HC; N = 519), clinical controls with a mood disorder but without STBs (CC; N = 246) and young people with current suicidal ideation (N = 223). In separate analyses, MRI metrics were compared among HCs (N = 253), CCs (N = 217), and suicide attempters (N = 64). Third, in a larger transdiagnostic sample with various assessment instruments (HC = 606; CC = 419; Ideation = 289; HC = 253; CC = 432; Attempt=91). In the homogeneous C-SSRS sample, surface area of the frontal pole was lower in young people with mood disorders and a history of actual suicide attempts (N = 163) than those without a lifetime suicide attempt (N = 323; FDR-p = 0.035, Cohen’s d = 0.34). No associations with suicidal ideation were found. When examining more heterogeneous samples, we did not observe significant associations. Lower frontal pole surface area may represent a vulnerability for a (non-interrupted and non-aborted) suicide attempt; however, more research is needed to understand the nature of its relationship to suicide risk.

Published
2022

8. Extracorporeal membrane oxygenation (ECMO) and the acute respiratory distress syndrome (ARDS): a systematic review of pre-clinical models

Author

Millar, Jonathan E., Bartnikowski, Nicole, von Bahr, Viktor, Malfertheiner, Maximilian V., Obonyo, Nchafatso G., Belliato, Mirko, Suen, Jacky Y., Combes, Alain, McAuley, Daniel F., Lorusso, Roberto, Fraser, John F., on behalf of the European Extracorporeal Life Support Organisation (EuroELSO) Innovations Workgroup, and the National Health Medical Research Council Australia Centre of Research Excellence for Advanced Cardio-respiratory Therapies Improving Organ Support (NHMRC CREACTIONS)

Published
2019
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10. The genetic architecture of the human cerebral cortex

Author

Universidad de Sevilla. Departamento de Psiquiatría, 23andMe, AbbVie, Alzheimer's Association, Alzheimer's Drug Discovery Foundation, Araclon Biotech, Australian NHMRC, Bayer Healthcare, AG, Bergen Research Foundation, BioClinica, Inc., Biogen, BMBF through the Integrated Network IntegraMent under the e:Med Program, Bristol-Myers Squibb Company, Canadian Institutes of Health Research, CereSpir, Inc., Cogstate, Department of Defense ADNI, Dr Einar Martens Fund, Eisai Inc., Elan Pharmaceuticals, Inc., Eli Lilly and Company, EuroImmun, European Research Council (ERC) under the European Union's Horizon 2020 research and innovation program (H2020), F. Hoffmann-La Roche, Ltd., Fujirebio, GE Healthcare, Genentech, Inc., German Federal Ministry of Education and Science (BMBF), German Research Foundation (DFG), Heinz Nixdorf Foundation (Germany), HelseVest RHF, Initiative and Networking Fund of the Helmholtz Association, IXICO Ltd., Janssen Alzheimer Immunotherapy Research AMP; Development, LLC., Johnson AMP; Johnson Pharmaceutical Research AMP; Development, LLC, K.G. Jebsen Foundation, Kavli Foundation, Lumosity, Lundbeck, Macquarie Group Foundation, Merck Co., Inc., Meso Scale Diagnostics, LLC, Michael J. Fox Foundation (MJFF), National Health and Medical Research Council (NHMRC), National Institute of Biomedical Imaging and Bioengineering, National Institute on Aging (NIA), National Institutes of Health (NIH) Big Data to Knowledge (BD2K) Initiative, a cross-NIH partnership, Neurobehavioral Genetics Unit, NeuroRx Research, Neurotrack Technologies, NHMRC, NHMRC Senior Research Fellowship, APP1103623, NIH U01, NLM, Novartis Pharmaceuticals Corporation, NSW Health, Pfizer, Inc., Piramal Imaging, Pratt Foundation, QIMR Berghofer Fellowship, Ramsay Health Care, Research Council of Norway, Schizophrenia Research Institute (Australia), Servier, Swiss National Science Foundation, Takeda Pharmaceutical Company, Torsten and Ragnar Soderbergs Foundation, Transition Therapeutics, UK Medical Research Council (MRC), University of Bergen, Viertel Charitable Foundation, Wallenberg Scholar grant from the Knut and Alice Wallenberg Foundation, Wellcome, Grasby, Katrina L, Jahanshad, Neda, Painter, Jodie N., Colodro-Conde, Lucía, Bralten, Janita, Hibar, Derrek P., Crespo Facorro, Benedicto, Universidad de Sevilla. Departamento de Psiquiatría, 23andMe, AbbVie, Alzheimer's Association, Alzheimer's Drug Discovery Foundation, Araclon Biotech, Australian NHMRC, Bayer Healthcare, AG, Bergen Research Foundation, BioClinica, Inc., Biogen, BMBF through the Integrated Network IntegraMent under the e:Med Program, Bristol-Myers Squibb Company, Canadian Institutes of Health Research, CereSpir, Inc., Cogstate, Department of Defense ADNI, Dr Einar Martens Fund, Eisai Inc., Elan Pharmaceuticals, Inc., Eli Lilly and Company, EuroImmun, European Research Council (ERC) under the European Union's Horizon 2020 research and innovation program (H2020), F. Hoffmann-La Roche, Ltd., Fujirebio, GE Healthcare, Genentech, Inc., German Federal Ministry of Education and Science (BMBF), German Research Foundation (DFG), Heinz Nixdorf Foundation (Germany), HelseVest RHF, Initiative and Networking Fund of the Helmholtz Association, IXICO Ltd., Janssen Alzheimer Immunotherapy Research AMP; Development, LLC., Johnson AMP; Johnson Pharmaceutical Research AMP; Development, LLC, K.G. Jebsen Foundation, Kavli Foundation, Lumosity, Lundbeck, Macquarie Group Foundation, Merck Co., Inc., Meso Scale Diagnostics, LLC, Michael J. Fox Foundation (MJFF), National Health and Medical Research Council (NHMRC), National Institute of Biomedical Imaging and Bioengineering, National Institute on Aging (NIA), National Institutes of Health (NIH) Big Data to Knowledge (BD2K) Initiative, a cross-NIH partnership, Neurobehavioral Genetics Unit, NeuroRx Research, Neurotrack Technologies, NHMRC, NHMRC Senior Research Fellowship, APP1103623, NIH U01, NLM, Novartis Pharmaceuticals Corporation, NSW Health, Pfizer, Inc., Piramal Imaging, Pratt Foundation, QIMR Berghofer Fellowship, Ramsay Health Care, Research Council of Norway, Schizophrenia Research Institute (Australia), Servier, Swiss National Science Foundation, Takeda Pharmaceutical Company, Torsten and Ragnar Soderbergs Foundation, Transition Therapeutics, UK Medical Research Council (MRC), University of Bergen, Viertel Charitable Foundation, Wallenberg Scholar grant from the Knut and Alice Wallenberg Foundation, Wellcome, Grasby, Katrina L, Jahanshad, Neda, Painter, Jodie N., Colodro-Conde, Lucía, Bralten, Janita, Hibar, Derrek P., and Crespo Facorro, Benedicto

Abstract

INTRODUCTION The cerebral cortex underlies our complex cognitive capabilities. Variations in human cortical surface area and thickness are associated with neurological, psychological, and behavioral traits and can be measured in vivo by magnetic resonance imaging (MRI). Studies in model organisms have identified genes that influence cortical structure, but little is known about common genetic variants that affect human cortical structure. RATIONALE To identify genetic variants associated with human cortical structure at both global and regional levels, we conducted a genome-wide association meta-analysis of brain MRI data from 51,665 individuals across 60 cohorts. We analyzed the surface area and average thickness of the whole cortex and 34 cortical regions with known functional specializations. RESULTS We identified 369 nominally genome-wide significant loci (P < 5 × 10−8) associated with cortical structure in a discovery sample of 33,992 participants of European ancestry. Of the 360 loci for which replication data were available, 241 loci influencing surface area and 66 influencing thickness remained significant after replication, with 237 loci passing multiple testing correction (P < 8.3 × 10−10; 187 influencing surface area and 50 influencing thickness). Common genetic variants explained 34% (SE = 3%) of the variation in total surface area and 26% (SE = 2%) in average thickness; surface area and thickness showed a negative genetic correlation (rG = −0.32, SE = 0.05, P = 6.5 × 10−12), which suggests that genetic influences have opposing effects on surface area and thickness. Bioinformatic analyses showed that total surface area is influenced by genetic variants that alter gene regulatory activity in neural progenitor cells during fetal development. By contrast, average thickness is influenced by active regulatory elements in adult brain samples, which may reflect processes that occur after mid-fetal development, such as myelination, branching, or pruning. When co

Published
2020

12. Big data to real world evidence: Post-market surveillance of HER2-targeted therapies for metastatic breast cancer in Australia

Author

Pearson, Sallie, Public Health & Community Medicine, Faculty of Medicine, UNSW, Houssami, Nehmat, Sydney School of Public Health, Sydney Medical School, University of Sydney. Sydney, Australia, Lord, Sarah, School of Medicine, University of Notre Dame Australia; NHMRC Clinical Trials Centre, University of Sydney. Sydney, Australia, Kiely, Belinda, NHMRC Clinical Trials Centre, University of Sydney. Sydney, Australia, Daniels, Benjamin, Community Medicine, Faculty of Medicine, UNSW, Pearson, Sallie, Public Health & Community Medicine, Faculty of Medicine, UNSW, Houssami, Nehmat, Sydney School of Public Health, Sydney Medical School, University of Sydney. Sydney, Australia, Lord, Sarah, School of Medicine, University of Notre Dame Australia; NHMRC Clinical Trials Centre, University of Sydney. Sydney, Australia, Kiely, Belinda, NHMRC Clinical Trials Centre, University of Sydney. Sydney, Australia, and Daniels, Benjamin, Community Medicine, Faculty of Medicine, UNSW

Abstract

Regulatory, subsidy, and treatment decisions are based primarily on evidence from randomised clinical trials conducted in highly selected patient populations and under standardised conditions, limiting the extent to which outcomes can be extrapolated to the general population. Evidence from the real-world marketplace is needed to provide answers to many questions around the use and impact of cancer medicines. Traditionally, these issues have not been addressed systematically and the wealth of data generated by Australia’s universal health care system has been significantly underutilised, particularly with respect to post-market surveillance of cancer medicines. This dissertation utilises routinely collected Australian health data to generate real-world data around the use and impact of medicines to treat HER2-positive metastatic breast cancer (HER2+MBC), primarily trastuzumab. Between 2001–2015 trastuzumab for HER2+MBC was publicly subsidised by the Herceptin Program. This funding arrangement defined the largest cohort of HER2+MBC patients (n = 5,899), internationally, and created a unique data holding comprising linked medicine dispensings, medical service claims, and patient characteristics data for every woman in Australia treated with trastuzumab for HER2+MBC.We detail the patterns of treatment and survival outcomes; examine how regulatory policies impacted treatment; and explore patient sub-groups excluded from clinical trials. We found that patients received trastuzumab for longer than reported in clinical trials, though survival outcomes were similar and improved over the tenure of the Herceptin Program. Combination treatment with chemotherapy was widespread and often outside of regulatory guidelines, while a change to restrictions for lapatinib, resulted in a brief period of wider uptake. A sub-group of patients treated with neo/adjuvant trastuzumab who relapsed and again received trastuzumab for MBC had relatively short durations of treatment and survival o

Published
2018

18. Changes in attitudes and practices of optometrists in their management of diabetic retinopathy after the release of NHMRC guidelines.

Author

Wright, Ms Suzie, Ba, Suzie E Wright, Mph, Rob McKay Mbbs, Mph, Kathryn I Taylor Mbbs, PhD, Jill E Keeffe, Mph, Catherine A McCarty PhD, and Distribution, Working Group for the Evaluation of Nhmrc Retinopathy Guideline

Subjects
OPTOMETRISTS, DIABETIC retinopathy treatment
Abstract

ABSTRACT The purpose of this study was to document attitudes and practices of Australian optometrists in their management of diabetic retinopathy prior to the release of the National Health and Medical Research Council (NHMRC) Clinical Practice Guidelines for the Management of Diabetic Retinopathy and at two time points following their release. A self- administered questionnaire was mailed to a stratified random sample of 500 Australian optometrists at the three time points. The same sample was used for the first two surveys and a new random sample was drawn for the second follow-up survey. The response to the three questionnaires was 86%, 80% and 84%, respectively. More than 90% of optometrists reported receiving a copy of the guidelines and 82% reported receiving the supplementary Retinopathy Chart. Fifty-seven per cent reported having read the guidelines at least once in entirety and 65% reported that they refer to the Retinopathy Chart at least monthly in their clinical practice. There was a significant decrease in the number of optometrists who reported that patient unwillingness to be dilated and their fear of precipitating angle closure glaucoma were moderate or major barriers to performing dilated ophthalmoscopy. Concomitantly, the percentage of optometrists who reported that they often or always perform dilated ophthalmoscopy on new patients with diabetes increased significantly from 74.5% (95% confidence limit = 70.2, 78.8) to 81.5% (95% confidence limit = 77.5, 85.5). There have been some significant changes in the self-reported management practices of optometrists in relation to diabetic retinopathy since the release of the NHMRC guidelines and Retinopathy Chart. [ABSTRACT FROM AUTHOR]

Published
2001
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19. Seroprevalence and associated risk factors of Toxoplasma gondii infection in a representative Australian human population: The Busselton health study

Author

<p>This work was supported by the Joint Project of the Australian National Health and Medical Research Council (NHMRC) and the National Natural Science Foundation of China (NSFC) (NHMRC <a href="https://www.sciencedirect.com/science/article/pii/S2213398420300415?via%3Dihub#gs7">APP1112767</a>-NSFC <a href="https://www.sciencedirect.com/science/article/pii/S2213398420300415?via%3Dihub#gs8">81561128020</a>). Funds from the grant were used to purchase the ELISA kits used in this study.</p>, Molan, Aus, Nosaka, Kazunori, Hunter, Michael, Wang, Wei, <p>This work was supported by the Joint Project of the Australian National Health and Medical Research Council (NHMRC) and the National Natural Science Foundation of China (NSFC) (NHMRC <a href="https://www.sciencedirect.com/science/article/pii/S2213398420300415?via%3Dihub#gs7">APP1112767</a>-NSFC <a href="https://www.sciencedirect.com/science/article/pii/S2213398420300415?via%3Dihub#gs8">81561128020</a>). Funds from the grant were used to purchase the ELISA kits used in this study.</p>, Molan, Aus, Nosaka, Kazunori, Hunter, Michael, and Wang, Wei

Abstract

Molan, A., Nosaka, K., Hunter, M., & Wang, W. (2020). Seroprevalence and associated risk factors of Toxoplasma gondii infection in a representative Australian human population: The Busselton health study. Clinical Epidemiology and Global Health, 8(3), 808-814. doi: https://doi.org/10.1016/j.cegh.2020.02.005

20. Variable outcomes of human heart attack recapitulated in genetically diverse mice

Author

<p>...This work was supported by National Health and Medical Research Council (NHMRC) Australia Fellowship (546133, N.A.R.), Australian Research Council (ARC) Stem Cells Australia (SR1100102, N.A.R.), NHMRC/Heart Foundation Career Development Fellowship (1049980, M.R.), a trampoline grant from the Association Française contre les Myopathies (17822, K.J.N.), an Australian Research Council Future Fellowship (FT100100734, K.J.N.), an NHMRC Program Grant (1037321, G.M.), an NHMRC Project Grant (1069173, G.M.), and the Diabetes Research Foundation of WA (G.M.), a United States National Institutes of Health Research Grant (R01HL116449, J.W.H.).</p>, Salimova, Ekaterina, Nowak, Kristen J., Estrada, Ana C., Furtado, Milena B., McNamara, Elyshia, Nguyen, Quang, Balmer, Lois, Preuss, Christoph, Holmes, Jeffrey W., Ramialison, Mirana, Morahan, Grant, Rosenthal, Nadia A., <p>...This work was supported by National Health and Medical Research Council (NHMRC) Australia Fellowship (546133, N.A.R.), Australian Research Council (ARC) Stem Cells Australia (SR1100102, N.A.R.), NHMRC/Heart Foundation Career Development Fellowship (1049980, M.R.), a trampoline grant from the Association Française contre les Myopathies (17822, K.J.N.), an Australian Research Council Future Fellowship (FT100100734, K.J.N.), an NHMRC Program Grant (1037321, G.M.), an NHMRC Project Grant (1069173, G.M.), and the Diabetes Research Foundation of WA (G.M.), a United States National Institutes of Health Research Grant (R01HL116449, J.W.H.).</p>, Salimova, Ekaterina, Nowak, Kristen J., Estrada, Ana C., Furtado, Milena B., McNamara, Elyshia, Nguyen, Quang, Balmer, Lois, Preuss, Christoph, Holmes, Jeffrey W., Ramialison, Mirana, Morahan, Grant, and Rosenthal, Nadia A.

Abstract

Salimova, E., Nowak, K. J., Estrada, A. C., Furtado, M. B., McNamara, E., Nguyen, Q., ... Rosenthal, N. A. (2019). Variable outcomes of human heart attack recapitulated in genetically diverse mice. Nature Partner Journals Regenerative Medicine, 4(1), Article 5. Available here

21. Controlled ecological evaluation of an implemented exercise-training programme to prevent lower limb injuries in sport: Population-level trends in hospital-treated injuries

Author

<p>This study was funded by a National Health and Medical Research Council (NHMRC) Partnership Project Grant (ID 565907) with additional support (both cash and in kind) from the project partner agencies: the Australian Football League (AFL); Victorian Health Promotion Foundation (VicHealth); NSW Sporting Injuries Committee (NSWSIC); JLT Sport, a division of Jardine Lloyd Thompson Australia Pty Ltd; the Department of Planning and Community Development; Sport and Recreation Victoria Division (SRV) and Sports Medicine Australia National and Victorian Branches (SMA). CFF was partially supported by an NHMRC Principal Research Fellowship (ID1058737). JLC was supported by a NHMRC practitioner fellowship (ID1058493). AD received full salary support from the NHMRC Partnership Project Grant. Aspects of this research are related to the work of the Australian Centre for Research into Injury in Sport and its Prevention (ACRISP), which is one of the IOC centres of research excellence for the prevention of injuries and promotion of health in athletes.</p>, Finch, Caroline F., Gray, Shannon E., Akram, Muhammad, Donaldson, Alex, Lloyd, David G., Cook, Jill L., <p>This study was funded by a National Health and Medical Research Council (NHMRC) Partnership Project Grant (ID 565907) with additional support (both cash and in kind) from the project partner agencies: the Australian Football League (AFL); Victorian Health Promotion Foundation (VicHealth); NSW Sporting Injuries Committee (NSWSIC); JLT Sport, a division of Jardine Lloyd Thompson Australia Pty Ltd; the Department of Planning and Community Development; Sport and Recreation Victoria Division (SRV) and Sports Medicine Australia National and Victorian Branches (SMA). CFF was partially supported by an NHMRC Principal Research Fellowship (ID1058737). JLC was supported by a NHMRC practitioner fellowship (ID1058493). AD received full salary support from the NHMRC Partnership Project Grant. Aspects of this research are related to the work of the Australian Centre for Research into Injury in Sport and its Prevention (ACRISP), which is one of the IOC centres of research excellence for the prevention of injuries and promotion of health in athletes.</p>, Finch, Caroline F., Gray, Shannon E., Akram, Muhammad, Donaldson, Alex, Lloyd, David G., and Cook, Jill L.

Abstract

Finch, C. F., Gray, S. E., Akram, M., Donaldson, A., Lloyd, D. G., & Cook, J. L. (2019). Controlled ecological evaluation of an implemented exercise-training programme to prevent lower limb injuries in sport: population-level trends in hospital-treated injuries. British Journal of Sports Medicine, 53(8), 487–492. Available here

23. Dementia prevention: the time to act is now.

Author

Chong, Terence WH, Macpherson, Helen, Schaumberg, Mia A, Brown, Belinda M, Naismith, Sharon L, Steiner, Genevieve Z, and NHMRC National Institute for Dementia Research, Dementia Prevention Special Interest Group*

Abstract

Keywords: Dementia; Prevention and control; Alzheimer disease; Public health; Risk factors; Neurocognitive disorders EN Dementia Prevention and control Alzheimer disease Public health Risk factors Neurocognitive disorders 302 302 1 04/21/21 20210415 NES 210415 A multilayered action plan is needed for a substantial, timely and sustained investment in dementia prevention In 2012, the Australian Government declared dementia as the ninth National Health Priority Area. Mobilise peak health advocacy bodies to promote and coordinate public health messaging on dementia risk factors that cut across chronic conditions. b How do we ensure value for money and sustainability of dementia prevention public health campaigns? Resource and coordinate a whole-of-community approach including government, public and private health care, community services and education sectors to operationalise guidelines and multifaceted dementia prevention programs throughout life. b Dementia prevention is everyone's business. [Extracted from the article]

Published
2021
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24. The urinary peptidome as a noninvasive biomarker development strategy for prenatal screening of Down's syndrome

Author

<p>National Natural Science Foundation of China (Grant Numbers: 51673119, 81773527, 81273170, 81370083, and 81573215)</p> <p>Australia-China International Collaborative Grant (NHMRC APP1112767 - NSFC 81561128020).</p> <p>China Scholarship Council (CSC Number: 201708110200).</p>, Shan, Dan, Wang, Hao, Khatri, Prekshya, Niu, Yue, Song, Wei, Zhao, Shenglong, Jiang, Yan, Ma, Qingwei, Liu, Xinchao, Zhang, Rong, Wang, Wei, Yin, Chenghong, <p>National Natural Science Foundation of China (Grant Numbers: 51673119, 81773527, 81273170, 81370083, and 81573215)</p> <p>Australia-China International Collaborative Grant (NHMRC APP1112767 - NSFC 81561128020).</p> <p>China Scholarship Council (CSC Number: 201708110200).</p>, Shan, Dan, Wang, Hao, Khatri, Prekshya, Niu, Yue, Song, Wei, Zhao, Shenglong, Jiang, Yan, Ma, Qingwei, Liu, Xinchao, Zhang, Rong, Wang, Wei, and Yin, Chenghong

Abstract

Shan, D., Wang, H., Khatri, P., Niu, Y., Song, W., Zhao, S., ... Yin, C. (2019). The urinary peptidome as a noninvasive biomarker development strategy for prenatal screening of Down's syndrome. Omics: A Journal of Integrative Biology, 23(9), 439-447. Available here

25. Type 2 diabetes mellitus is associated with the immunoglobulin G N-glycome through putative proinflammatory mechanisms in an Australian population

Author

<p>National Health and Medical Research Council (NHMRC).</p> <p>Further funding information available at: <a href="https://doi.org/10.1089/omi.2019.0075" target="_blank" title="Link to publication">https://doi.org/10.1089/omi.2019.0075</a></p>, Li, Xingang, Wang, Hao, Russell, Alyce, Cao, Weijie, Wang, Xueqing, Ge, Siqi, Zheng, Yulu, Guo, Zheng, Hou, Haifeng, Song, Manshu, Yu, Xinwei, Wang, Youxin, Hunter, Michael, Roberts, Peter, Lauc, Gordan, Wang, Wei, <p>National Health and Medical Research Council (NHMRC).</p> <p>Further funding information available at: <a href="https://doi.org/10.1089/omi.2019.0075" target="_blank" title="Link to publication">https://doi.org/10.1089/omi.2019.0075</a></p>, Li, Xingang, Wang, Hao, Russell, Alyce, Cao, Weijie, Wang, Xueqing, Ge, Siqi, Zheng, Yulu, Guo, Zheng, Hou, Haifeng, Song, Manshu, Yu, Xinwei, Wang, Youxin, Hunter, Michael, Roberts, Peter, Lauc, Gordan, and Wang, Wei

Abstract

Li, X., Wang, H., Russell, A., Cao, W., Wang, X., Ge, S., ... & Yu, X. (2019).Type 2 diabetes mellitus is associated with the immunoglobulin G N-glycome through putative proinflammatory mechanisms in an Australian population. OMICS: A Journal of Integrative Biology, 23(12), 631-639. Available here

26. Next-generation (glycomic) biomarkers for cardiometabolic health: A community-based study of immunoglobulin G N-glycans in a Chinese Han population

Author

<p>National Health and Medical Research Council (NHMRC).</p> <p>Further funding information available at: <a href="https://doi.org/10.1089/omi.2019.0099" target="_blank" title="Link to publication">https://doi.org/10.1089/omi.2019.0099</a></p>, Wang, Hao, Li, Xingang, Wang, Xueqing, Liu, Di, Zhang, Xiaoyu, Cao, Weijie, Zheng, Yulu, Guo, Zheng, Li, Dong, Xing, Weijia, Hou, Haifeng, Wu, Lijuan, Song, Manshu, Zhong, Zhaohua, Wang, Youxin, Tan, Xuerui, Lauc, Gordan, Wang, Wei, <p>National Health and Medical Research Council (NHMRC).</p> <p>Further funding information available at: <a href="https://doi.org/10.1089/omi.2019.0099" target="_blank" title="Link to publication">https://doi.org/10.1089/omi.2019.0099</a></p>, Wang, Hao, Li, Xingang, Wang, Xueqing, Liu, Di, Zhang, Xiaoyu, Cao, Weijie, Zheng, Yulu, Guo, Zheng, Li, Dong, Xing, Weijia, Hou, Haifeng, Wu, Lijuan, Song, Manshu, Zhong, Zhaohua, Wang, Youxin, Tan, Xuerui, Lauc, Gordan, and Wang, Wei

Abstract

Wang, H., Li, X., Wang, X., Liu, D., Zhang, X., Cao, W., ... Wei, W. (2019). Next-generation (glycomic) biomarkers for cardiometabolic health: A community-based study of immunoglobulin G N-glycans in a Chinese Han population. OMICS: A Journal of Integrative Biology, 23(12), 649-659. Available here

27. Population-based case-control study revealed metabolomic biomarkers of suboptimal health status in Chinese population—potential utility for innovative approach by predictive, preventive, and personalized medicine

Author

<p>This work was partially supported by National Natural Science Foundation of China (Grant Numbers: 81673247 & 81773527) and China- Australia International Collaborative Grant (NSFC 81561128020, NHMRC APP1112767). HW and XW were supported by the China Scholarship Council (CSC 201708110200 and CSC 201608230108).</p>, Wang, Hao, Tian, Qiuyue, Zhang, Jie, Liu, Hongqi, Zhang, Xiaoyu, Cao, Weijie, Zhang, Jinxia, Anto, Enoch Odame, Li, Xingang, Wang, Xueqing, Liu, Di, Zheng, Yulu, Guo, Zheng, Wu, Lijuan, Song, Manshu, Wang, Youxin, Wang, Wei, <p>This work was partially supported by National Natural Science Foundation of China (Grant Numbers: 81673247 & 81773527) and China- Australia International Collaborative Grant (NSFC 81561128020, NHMRC APP1112767). HW and XW were supported by the China Scholarship Council (CSC 201708110200 and CSC 201608230108).</p>, Wang, Hao, Tian, Qiuyue, Zhang, Jie, Liu, Hongqi, Zhang, Xiaoyu, Cao, Weijie, Zhang, Jinxia, Anto, Enoch Odame, Li, Xingang, Wang, Xueqing, Liu, Di, Zheng, Yulu, Guo, Zheng, Wu, Lijuan, Song, Manshu, Wang, Youxin, and Wang, Wei

Abstract

This is a post-peer-review, pre-copyedit version of an article published in EPMA Journal. The final authenticated version is available online at: https://doi.org/10.1007/s13167-020-00200-7 Wang, H., Tian, Q., Zhang, J., Liu, H., Zhang, X., Cao, W., ... & Wang, W. (2020). Population-based case-control study revealed metabolomic biomarkers of suboptimal health status in Chinese population—potential utility for innovative approach by predictive, preventive, and personalized medicine. EPMA Journal, 11, 147 - 160.

28. Amylin and beta amyloid proteins interact to form amorphous heterocomplexes with enhanced toxicity in neuronal cells

Author

<p>Edith Cowan University - Open Access Support Scheme 2020</p> <p>NHMRC Dementia research development fellowship</p>, Bharadwaj, Prashant, Solomon, Tanya, Sahoo, Bikash, Ignasiak, Katarzyna, Gaskin, Scott, Rowles, Joanne, Verdile, Guiseppe, Howard, Mark, Bond, Charles S., Ramamoorthy, Ayyalusamy, Martins, Ralph, Newsholme, Philip, <p>Edith Cowan University - Open Access Support Scheme 2020</p> <p>NHMRC Dementia research development fellowship</p>, Bharadwaj, Prashant, Solomon, Tanya, Sahoo, Bikash, Ignasiak, Katarzyna, Gaskin, Scott, Rowles, Joanne, Verdile, Guiseppe, Howard, Mark, Bond, Charles S., Ramamoorthy, Ayyalusamy, Martins, Ralph, and Newsholme, Philip

Abstract

Bharadwaj, P., Solomon, T., Sahoo, B.R., Ignasiak, K., Gaskin, S., Rowles, J., ... & Martins, R. N. (2020). Amylin and beta amyloid proteins interact to form amorphous heterocomplexes with enhanced toxicity in neuronal cells. Scientific Reports, 10 Article 10356. https://doi.org/10.1038/s41598-020-66602-9

29. Deciding to enrol in a cancer trial: A systematic review of qualitative studies

Author

<p>NHMRC Centre for Research Excellence in Prostate Cancer Survivorship</p>, Viljoen, Bianca, Chambers, Suzanne K., Dunn, Jeff, Ralph, Nicholas, March, Sonja, <p>NHMRC Centre for Research Excellence in Prostate Cancer Survivorship</p>, Viljoen, Bianca, Chambers, Suzanne K., Dunn, Jeff, Ralph, Nicholas, and March, Sonja

Abstract

Viljoen, B., Chambers, S. K., Dunn, J., Ralph, N., & March, S. (2020). Deciding to enrol in a cancer trial: A systematic review of qualitative studies. Journal of Multidisciplinary Healthcare, 13, 1257-1281. https://doi.org/10.2147/JMDH.S266281

30. Impaired central drive to plantarflexors and minimal ankle proprioceptive deficit in people with multiple sclerosis

Author

<p>NHMRC Program Grant on Motor Impairment</p>, Djajadikarta, Zoë J., Dongés, Siobhan C., Brooks, Jack, Kennedy, David S., Gandevia, Simon C., Taylor, Janet L., <p>NHMRC Program Grant on Motor Impairment</p>, Djajadikarta, Zoë J., Dongés, Siobhan C., Brooks, Jack, Kennedy, David S., Gandevia, Simon C., and Taylor, Janet L.

Abstract

Djajadikarta, Z. J., Dongés, S. C., Brooks, J., Kennedy, D. S., Gandevia, S. C., & Taylor, J. L. (2020). Impaired central drive to plantarflexors and minimal ankle proprioceptive deficit in people with multiple sclerosis. Multiple Sclerosis and Related Disorders, 46, article 102584. https://doi.org/10.1016/j.msard.2020.102584

31. Prostate cancer survivorship priorities for men and their partners: Delphi consensus from a nurse specialist cohort

Author

<p>National Health and Medical Research Council (NHMRC). </p> <p>Prostate Cancer Foundation of Australia.</p>, Ralph, Nicholas, Green, Anna, Sara, Sally, McDonald, Suzanne, Norris, Philip, Terry, Victoria, Dunn, Jeffrey C., Chambers, Suzanne K., <p>National Health and Medical Research Council (NHMRC). </p> <p>Prostate Cancer Foundation of Australia.</p>, Ralph, Nicholas, Green, Anna, Sara, Sally, McDonald, Suzanne, Norris, Philip, Terry, Victoria, Dunn, Jeffrey C., and Chambers, Suzanne K.

Abstract

Ralph, N., Green, A., Sara, S., McDonald, S., Norris, P., Terry, V., ... Chambers, S. K. (2020). Prostate cancer survivorship priorities for men and their partners: Delphi consensus from a nurse specialist cohort. Journal of Clinical Nursing, 29(1-2), 265-273. https://doi.org/10.1111/jocn.15096

32. Considerations for multi-centre conditioned pain modulation (CPM) research; an investigation of the inter-rater reliability, level of agreement and confounders for the Achilles tendon and Triceps Surae

Author

<p>Australian Government Research Training Program (RTP) Fee Offset Scholarship NHMRC Early Career Fellowship</p>, Murphy, Myles, Gibson, William, Chivers, Paola, Docking, Sean, Rio, Ebonie, <p>Australian Government Research Training Program (RTP) Fee Offset Scholarship NHMRC Early Career Fellowship</p>, Murphy, Myles, Gibson, William, Chivers, Paola, Docking, Sean, and Rio, Ebonie

Abstract

This is an author's accepted manuscript of: Murphy, M., Gibson, W., Chivers, P., Docking, S., & Rio, E. (2021). Considerations for multi-centre conditioned pain modulation (CPM) research; an investigation of the inter-rater reliability, level of agreement and confounders for the Achilles tendon and triceps surae. British Journal of Pain, 15(1), 91-101. SAGE. https://doi.org/10.1177/2049463720912208

33. When a health policy cuts both ways: Impact of the National Emergency Access Target policy on staff and emergency department performance

Author

<p>This project was funded by the Australian National Health and Medical Research Council (NHMRC) Partnership Grant No. APP1029492 with cash contributions from the following organisations: Department of Health of Western Australia, Australasian College for Emergency Medicine, Ministry of Health of NSW and the Emergency Care Institute, NSW Agency for Clinical Innovation, and the Emergency Medicine Foundation, Queensland.</p>, Forero, Roberto, Man, Nicola, Nahidi, Shizar, Fitzgerald, Gerard, Fatovich, Daniel, Mohsin, Mohammed, Ngo, Hanh, Toloo, Ghasem (Sam), Gibson, Nick, McCarthy, Sally, Mountain, David, Hillman, Ken, <p>This project was funded by the Australian National Health and Medical Research Council (NHMRC) Partnership Grant No. APP1029492 with cash contributions from the following organisations: Department of Health of Western Australia, Australasian College for Emergency Medicine, Ministry of Health of NSW and the Emergency Care Institute, NSW Agency for Clinical Innovation, and the Emergency Medicine Foundation, Queensland.</p>, Forero, Roberto, Man, Nicola, Nahidi, Shizar, Fitzgerald, Gerard, Fatovich, Daniel, Mohsin, Mohammed, Ngo, Hanh, Toloo, Ghasem (Sam), Gibson, Nick, McCarthy, Sally, Mountain, David, and Hillman, Ken

Abstract

Forero, R., Man, N., Nahidi, S., Fitzgerald, G., Fatovich, D., Mohsin, M., ... & Hillman, K. (2020). When a health policy cuts both ways: Impact of the National Emergency Access Target policy on staff and emergency department performance. Emergency Medicine Australasia. 32(2) 228 - 239. Available here.

34. Amla therapy as a potential modulator of Alzheimer's disease risk factors and physiological change

Author

<p>Edith Cowan University, ECU</p> <p>BrightFocus Foundation</p> <p>National Health and Medical Research Council, NHMRC</p> <p>Curtin University of Technology</p>, Teimouri, Elham, Rainey-Smith, Stephanie, Bharadwaj, Prashant, Verdile, Giuseppe, Martins, Ralph N., <p>Edith Cowan University, ECU</p> <p>BrightFocus Foundation</p> <p>National Health and Medical Research Council, NHMRC</p> <p>Curtin University of Technology</p>, Teimouri, Elham, Rainey-Smith, Stephanie, Bharadwaj, Prashant, Verdile, Giuseppe, and Martins, Ralph N.

Abstract

Teimouri, E., Rainey-Smith, S. R., Bharadwaj, P., Verdile, G., & Martins, R. N. (2020). Amla therapy as a potential modulator of Alzheimer's disease risk factors and physiological change. Journal of Alzheimer's Disease, 74(3), 713-733. https://doi.org/10.3233/JAD-191033

35. Modelling biological age based on plasma peptides in Han Chinese adults

Author

<p>This work was supported by grants from the National Natural Science Foundation of China (NSFC) (81673247, 81872682 and 81773527), the Joint Project of the NSFC and the Australian National Health and Medical Research Council (NHMRC) (NSFC 81561128020-NHMRC APP1112767).</p>, Cao, Weijie, Zheng, Deqiang, Wang, Guohua, Zhang, Jie, Ge, Siqi, Singh, Manjot, Wang, Hao, Song, Manshu, Li, Dong, Wang, Wei, Wang, Youxin, <p>This work was supported by grants from the National Natural Science Foundation of China (NSFC) (81673247, 81872682 and 81773527), the Joint Project of the NSFC and the Australian National Health and Medical Research Council (NHMRC) (NSFC 81561128020-NHMRC APP1112767).</p>, Cao, Weijie, Zheng, Deqiang, Wang, Guohua, Zhang, Jie, Ge, Siqi, Singh, Manjot, Wang, Hao, Song, Manshu, Li, Dong, Wang, Wei, and Wang, Youxin

Abstract

Cao, W., Zheng, D., Wang, G., Zhang, J., Ge, S., Singh, M., ... & Xu, X. (2020). Modelling biological age based on plasma peptides in Han Chinese adults. Aging, 12(11). https://doi.org/10.18632/aging.103286

36. Roles of bone-derived hormones in type 2 diabetes and cardiovascular pathophysiology

Author

<p>This work was supported by the National Health and Medical Research Council (NHMRC) of Australia in the form of a project grants 1156634 & 1158242 to K.L. The salary of J.L. is supported by a National Heart Foundation Future Leader Fellowship (ID: 102817).</p>, Lin, Xuzhu, Onda, Danise-Ann, Yang, Chien-Hsin, Lewis, Joshua R., Levinger, Itamar, Loh, Kim, <p>This work was supported by the National Health and Medical Research Council (NHMRC) of Australia in the form of a project grants 1156634 & 1158242 to K.L. The salary of J.L. is supported by a National Heart Foundation Future Leader Fellowship (ID: 102817).</p>, Lin, Xuzhu, Onda, Danise-Ann, Yang, Chien-Hsin, Lewis, Joshua R., Levinger, Itamar, and Loh, Kim

Abstract

Lin, X., Onda, D. A., Yang, C. H., Lewis, J., Levinger, I., & Loh, K. (2020). Roles of Bone-derived Hormones in Type 2 Diabetes and Cardiovascular Pathophysiology. Molecular Metabolism, Article no. 101040. https://doi.org/10.1016/j.molmet.2020.101040

37. Detection and prognostic role of heterogeneous populations of melanoma circulating tumour cells

Author

<p>Edith Cowan University, ECU</p> <p>National Health and Medical Research Council, NHMRC</p>, Aya-Bonilla, Carlos Alberto, Morici, Michael, Hong, Xin, McEvoy, Ashleigh Cavell, Sullivan, Ryan Joseph, Freeman, James, Calapre, Leslie, Khattak, Muhammad Adnan, Meniawy, Tarek, Millward, Michael, Ziman, Mel, Gray, Elin Solomonovna, <p>Edith Cowan University, ECU</p> <p>National Health and Medical Research Council, NHMRC</p>, Aya-Bonilla, Carlos Alberto, Morici, Michael, Hong, Xin, McEvoy, Ashleigh Cavell, Sullivan, Ryan Joseph, Freeman, James, Calapre, Leslie, Khattak, Muhammad Adnan, Meniawy, Tarek, Millward, Michael, Ziman, Mel, and Gray, Elin Solomonovna

Abstract

Aya-Bonilla, C. A., Morici, M., Hong, X., McEvoy, A. C., Sullivan, R. J., Freeman, J., ... & Ziman, M. (2020). Detection and prognostic role of heterogeneous populations of melanoma circulating tumour cells. British Journal of Cancer, 122(7), 1059-1067. https://doi.org/10.1038/s41416-020-0750-9

38. Global status of toxoplasma gondii infection: Systematic review and prevalence snapshots

Author

<p>Australian National Health and Medical Research Council (NHMRC) .</p> <p>National Natural Science Foundation of China (NSFC).</p>, Molan, A., Nosaka, K., Hunter, M., Wang, Wei, <p>Australian National Health and Medical Research Council (NHMRC) .</p> <p>National Natural Science Foundation of China (NSFC).</p>, Molan, A., Nosaka, K., Hunter, M., and Wang, Wei

Abstract

Molan, A., Nosaka, K., Hunter, M., & Wang, W. (2019). Global status of toxoplasma gondii infection: Systematic review and prevalence snapshots. Tropical Biomedicine, 36(4), 898-925. http://msptm.org/vol-36-no-4-dec/

39. Bowel patterns, gastrointestinal symptoms, and emotional well-being in adolescents: A cohort study

Author

<p>National Health and Medical Research Council (NHMRC).</p> <p>Raine Medical Research Foundation.</p> <p>Further funding information available at: <a href="https://doi.org/10.1111/jgh.14699" target="_blank" title="Link to publication">https://doi.org/10.1111/jgh.14699</a></p>, Ayonrinde, Oyekoya T., Sanfilippo, Frank M., O'Sullivan, Therese A ., Adams, Leon A., Ayonrinde, Oyedeji A., Robinson, Monique, Oddy, Wendy H., Olynyk, John K., <p>National Health and Medical Research Council (NHMRC).</p> <p>Raine Medical Research Foundation.</p> <p>Further funding information available at: <a href="https://doi.org/10.1111/jgh.14699" target="_blank" title="Link to publication">https://doi.org/10.1111/jgh.14699</a></p>, Ayonrinde, Oyekoya T., Sanfilippo, Frank M., O'Sullivan, Therese A ., Adams, Leon A., Ayonrinde, Oyedeji A., Robinson, Monique, Oddy, Wendy H., and Olynyk, John K.

Abstract

Ayonrinde, O. T., Sanfilippo, F. M., O'Sullivan, T. A., Adams, L. A., Ayonrinde, O. A., Robinson, M., ... Olynyk, J. K. (2019). Bowel patterns, gastrointestinal symptoms and emotional well‐being in adolescents–A cohort study. Journal of Gastroenterology and Hepatology, 34(11), 1946-1954. Available here

40. Combining whole-school and targeted programs for the reduction of bullying victimization: A randomized, effectiveness trial

Author

<p>National Health and Medical Research Council, NHMRC Macquarie University Australian Research Council, ARC</p>, Rapee, Ronald M., Shaw, Therese, Hunt, Caroline, Bussey, Kay, Hudson, Jennifer L., Mihalopoulos, Catherine, Roberts, Clare, Fitzpatrick, Sally, Radom, Naomi, Cordin, Tommy, Epstein, Melanie, Cross, Donna, <p>National Health and Medical Research Council, NHMRC Macquarie University Australian Research Council, ARC</p>, Rapee, Ronald M., Shaw, Therese, Hunt, Caroline, Bussey, Kay, Hudson, Jennifer L., Mihalopoulos, Catherine, Roberts, Clare, Fitzpatrick, Sally, Radom, Naomi, Cordin, Tommy, Epstein, Melanie, and Cross, Donna

Abstract

Rapee, R. M., Shaw, T., Hunt, C., Bussey, K., Hudson, J. L., Mihalopoulos, C., ... & Epstein, M. (2020). Combining whole‐school and targeted programs for the reduction of bullying victimization: A randomized, effectiveness trial. Aggressive Behavior, 46(3), 193-209. https://doi.org/10.1002/ab.21881

41. Multidisciplinary rehabilitation reduces hypothalamic grey matter volume loss in individuals with preclinical Huntington's disease: A nine-month pilot study

Author

<p>Lotterywest.</p> <p>Wellcome trust.</p> <p>National Health and Medical Research Council (NHMRC).</p>, Bartlett, Danielle M., Dominguez D., Juan F., Lazar, Alpar S., Kordsachia, Catarina C., Rankin, Tim J., Lo, Johnny, Govus, Andrew D., Power, Brian D., Lampit, Amit, Eastwood, Peter R., Ziman, Mel R., Cruickshank, Travis M., <p>Lotterywest.</p> <p>Wellcome trust.</p> <p>National Health and Medical Research Council (NHMRC).</p>, Bartlett, Danielle M., Dominguez D., Juan F., Lazar, Alpar S., Kordsachia, Catarina C., Rankin, Tim J., Lo, Johnny, Govus, Andrew D., Power, Brian D., Lampit, Amit, Eastwood, Peter R., Ziman, Mel R., and Cruickshank, Travis M.

Abstract

Bartlett, D. M., Lazar, A. S., Kordsachia, C. C., Rankin, T. J., Lo, J., Govus, A. D., ... & Cruickshank, T. M. (2020). Multidisciplinary rehabilitation reduces hypothalamic grey matter volume loss in individuals with preclinical Huntington's disease: A nine-month pilot study. Journal of the Neurological Sciences, 408, Article 116522. https://doi.org/10.1016/j.jns.2019.116522

42. Benefit–cost analysis of an interprofessional education program within a residential aged care facility in Western Australia

Author

<p>National Health and Medical Research Council (NHMRC) Cognitive Decline Partnership Centre (CDPC).</p>, Nguyen, Kim-Huong, Seaman, Karla, Saunders, Rosemary, Williams, Elly, Harrup-Gregory, Jane, Comans, Tracy, <p>National Health and Medical Research Council (NHMRC) Cognitive Decline Partnership Centre (CDPC).</p>, Nguyen, Kim-Huong, Seaman, Karla, Saunders, Rosemary, Williams, Elly, Harrup-Gregory, Jane, and Comans, Tracy

Abstract

Nguyen, K. H., Seaman, K., Saunders, R., Williams, E., Harrup-Gregory, J., & Comans, T. (2019). Benefit–cost analysis of an interprofessional education program within a residential aged care facility in Western Australia. Journal of Interprofessional Care, 33(6), 619-627. Available here

43. The detection of CMV in saliva can mark a systemic infection with CMV in renal transplant recipients

Author

<p>National Health and Medical Research Council of Australia (NHMRC)</p> <p>Curtin University</p>, Waters, Shelley, Lee, Silvia, Lloyd, Megan, Irish, Ashley, Price, Patricia, <p>National Health and Medical Research Council of Australia (NHMRC)</p> <p>Curtin University</p>, Waters, Shelley, Lee, Silvia, Lloyd, Megan, Irish, Ashley, and Price, Patricia

Abstract

Waters, S., Lee, S., Lloyd, M., Irish, A., & Price, P. (2019). The detection of CMV in saliva can mark a systemic infection with CMV in renal transplant recipients. International Journal of Molecular Sciences, 20(20). Available here.

44. Hyperuricemia is associated with immunoglobulin G N-glycosylation: A community-based study of glycan biomarkers

Author

<p>National Health and Medical Research Council (NHMRC).</p> <p>National Natural Science Foundation of China.</p> <p>National Key R&D Program of China.</p> <p>European Commission Horizon 2020.</p> <p>Science and Technology Development Project in Taian.</p>, Hou, Haifeng, Xu, Xizhu, Sun, Fengjing, Zhang, Xiaoyu, Dong, Hualei, Wang, Liang, Ge, Siqi, An, Kang, Sun, Qi, Li, Yuejin, Cao, Weijie, Song, Manshu, Hu, Shuangjie, Xing, Weijia, Wang, Wei, Li, Dong, Wang, Youxin, <p>National Health and Medical Research Council (NHMRC).</p> <p>National Natural Science Foundation of China.</p> <p>National Key R&D Program of China.</p> <p>European Commission Horizon 2020.</p> <p>Science and Technology Development Project in Taian.</p>, Hou, Haifeng, Xu, Xizhu, Sun, Fengjing, Zhang, Xiaoyu, Dong, Hualei, Wang, Liang, Ge, Siqi, An, Kang, Sun, Qi, Li, Yuejin, Cao, Weijie, Song, Manshu, Hu, Shuangjie, Xing, Weijia, Wang, Wei, Li, Dong, and Wang, Youxin

Abstract

Hou, H., Xu, X., Sun, F., Zhang, X., Dong, H., Wang, L., ... Wang, Y. (2019). Hyperuricemia is associated with immunoglobulin G N-glycosylation: A community-based study of glycan biomarkers. Omics: A Journal of Integrative Biology, 23(12), 660-667. Available here

45. Breastfeeding and nutrition to 2 years of age and risk of childhood acute lymphoblastic leukemia and brain tumors

Author

<p>NHMRC, National Health and Medical Research Council</p>, Greenop, Kathryn R., Bailey, Helen D., Millar, Margaret, Scott, Rodney J., Attia, John, Ashton, Lesley J., Downie, Peter, Armstrong, Bruce K., Milne, Elizabeth, <p>NHMRC, National Health and Medical Research Council</p>, Greenop, Kathryn R., Bailey, Helen D., Millar, Margaret, Scott, Rodney J., Attia, John, Ashton, Lesley J., Downie, Peter, Armstrong, Bruce K., and Milne, Elizabeth

Abstract

Greenop, K.R., Bailey, H.D., Miller, M., Scott, R.J., Attia, J., Ashton, L.J., Downie, P., Armstrong, B.K., Milne, E. (2015). Breastfeeding and nutrition to 2 years of age and risk of childhood acute lymphoblastic leukemia and brain tumors in Nutrition and Cancer, 67(3), 431-441. Available here.

46. Utilization of N-glycosylation profiles as risk stratification biomarkers for suboptimal health status and metabolic syndrome in a Ghanaian population

Author

<p>This study was supported partially by the Joint Project of the Australian National Health & Medical Research Council and the National Natural Science Foundation of China (NHMRC APP1112767-NSFC 81561128020), National Natural Science Foundation of China (grant numbers 8177120753, 81673247 and 81573215), Edith Cowan University Collaboration Enhancement Scheme 2017 (round 1), the National Key Technology Support Program of China (2012BAI37B03), as well as by funding from the European Structural and Investments funds for ‘Croatian National Centre of Research Excellence in Personalized Healthcare’ (contract no.KK.01.1.1.01.0010) and funding from the European Union’s Horizon 2020 research and innovation program under the Marie Sklodowska–Curie grant for project GlySign (contract no. 722095)</p>, Adua, Eric, Memarian, Elham, Russell, Alyce, Trbojević-Akmačić, Irena, Gudelj, Ivan, Jurić, Julija, Roberts, Peter, Lauc, Gordan, Wang, Wei, <p>This study was supported partially by the Joint Project of the Australian National Health & Medical Research Council and the National Natural Science Foundation of China (NHMRC APP1112767-NSFC 81561128020), National Natural Science Foundation of China (grant numbers 8177120753, 81673247 and 81573215), Edith Cowan University Collaboration Enhancement Scheme 2017 (round 1), the National Key Technology Support Program of China (2012BAI37B03), as well as by funding from the European Structural and Investments funds for ‘Croatian National Centre of Research Excellence in Personalized Healthcare’ (contract no.KK.01.1.1.01.0010) and funding from the European Union’s Horizon 2020 research and innovation program under the Marie Sklodowska–Curie grant for project GlySign (contract no. 722095)</p>, Adua, Eric, Memarian, Elham, Russell, Alyce, Trbojević-Akmačić, Irena, Gudelj, Ivan, Jurić, Julija, Roberts, Peter, Lauc, Gordan, and Wang, Wei

Abstract

Adua, E., Memarian, E., Russell, A., Trbojević-Akmačić, I., Gudelj, I., Jurić, J., ... & Wang, W. (2019). Utilization of N-glycosylation profiles as risk stratification biomarkers for suboptimal health status and metabolic syndrome in a Ghanaian population. Biomarkers in Medicine, 13(15), 1273-1287. Available here.

47. Why not use the immunoglobulin G N-glycans as predictor variables in disease biomarker-phenotype association studies? A multivariate analysis

Author

<p>National Health and Medical Research Council (NHMRC).</p> <p>Further funding information available at: <a href="https://doi.org/10.1089/omi.2019.0155" target="_blank" title="Link to publication">https://doi.org/10.1089/omi.2019.0155</a></p>, Russell, Alyce C., Kepka, Agnieszka, Trbojević-Akmačić, Irena, Ugrina, Ivo, Song, Manshu, <p>National Health and Medical Research Council (NHMRC).</p> <p>Further funding information available at: <a href="https://doi.org/10.1089/omi.2019.0155" target="_blank" title="Link to publication">https://doi.org/10.1089/omi.2019.0155</a></p>, Russell, Alyce C., Kepka, Agnieszka, Trbojević-Akmačić, Irena, Ugrina, Ivo, and Song, Manshu

Abstract

Russell, A. C., Kepka, A., Trbojević-Akmačić, I., Ugrina, I., Song, M., Hui, J., ... & Wang, W. (2019). Why not use the immunoglobulin G N-glycans as predictor variables in disease biomarker-phenotype association studies? A multivariate analysis. OMICS: A Journal of Integrative Biology, 23(12), 668-670. Available here

48. Glycomics for type 2 diabetes biomarker discovery: Promise of immunoglobulin G subclass-specific fragment crystallizable N-glycosylation in the Uyghur population

Author

<p>National Health and Medical Research Council (NHMRC).</p> <p>Further funding information available at: <a href="https://doi.org/10.1089/omi.2019.0052" target="_blank" title="Link to publication">https://doi.org/10.1089/omi.2019.0052</a> </p>, Liu, Jiaonan, Dolikun, Mamatyusupu, Štambuk, Jerko, Trbojević-Akmačić, Irena, Zhang, Jie, Zhang, Jinxia, Wang, Hao, Meng, Xiaoni, Razdorov, Genadij, Menon, Desmond, Zheng, Deqiang, Wu, Lijuan, Wang, Youxin, Song, Manshu, Lauc, Gordan, Wang, Wei, <p>National Health and Medical Research Council (NHMRC).</p> <p>Further funding information available at: <a href="https://doi.org/10.1089/omi.2019.0052" target="_blank" title="Link to publication">https://doi.org/10.1089/omi.2019.0052</a> </p>, Liu, Jiaonan, Dolikun, Mamatyusupu, Štambuk, Jerko, Trbojević-Akmačić, Irena, Zhang, Jie, Zhang, Jinxia, Wang, Hao, Meng, Xiaoni, Razdorov, Genadij, Menon, Desmond, Zheng, Deqiang, Wu, Lijuan, Wang, Youxin, Song, Manshu, Lauc, Gordan, and Wang, Wei

Abstract

Liu, J., Dolikun, M., Štambuk, J., Trbojević-Akmačić, I., Zhang, J., Zhang, J., ... Wang, W. (2019). Glycomics for type 2 diabetes biomarker discovery: Promise of immunoglobulin G subclass-specific fragment crystallizable N-glycosylation in the Uyghur population. OMICS: A Journal of Integrative Biology, 23(12), 640-648. Available here

49. Childhood folate, B6, B12, and food group intake and the risk of childhood brain tumors: results from an Australian case–control study

Author

<p>NHMRC, National Health and Medical Research Council</p>, Greenop, Kathryn R., Miller, Margaret, Bailey, Helen D., de Klerk, Nicholas H., Attia, John, Kellie, Stewart J., Bower, Carol, Armstrong, Bruce K., Milne, Elizabeth, <p>NHMRC, National Health and Medical Research Council</p>, Greenop, Kathryn R., Miller, Margaret, Bailey, Helen D., de Klerk, Nicholas H., Attia, John, Kellie, Stewart J., Bower, Carol, Armstrong, Bruce K., and Milne, Elizabeth

Abstract

Greenop, K.R., Miller, M., Bailey, H.D., de Klerk, N.H., Attia, J., Kellie, S.J., Bower, C., Armstrong, B.K., Milne, E. (2015). Childhood folate, B6, B12, and food group intake and the risk of childhood brain tumors: results from an Australian case–control study in Cancer Causes and Control, 26(6), 871-879. Available here.

50. Paternal dietary folate, B6 and B12 intake, and the risk of childhood brain tumors

Author

<p>NHMRC, National Health and Medical Research Council</p>, Greenop, Kathryn R., Miller, Margaret, Bailey, Helen D., Scott, Rodney J., Attia, John, Bower, Carol, van Bockxmeer, Frank M., Ashton, Lesley J., Armstrong, Bruce K., Milne, Elizabeth, <p>NHMRC, National Health and Medical Research Council</p>, Greenop, Kathryn R., Miller, Margaret, Bailey, Helen D., Scott, Rodney J., Attia, John, Bower, Carol, van Bockxmeer, Frank M., Ashton, Lesley J., Armstrong, Bruce K., and Milne, Elizabeth

Abstract

Greenop, K.R., Miller, M., Bailey, H.D., Scott, R.J., Attia, J., Bower, C., Van Bockxmeer, F.M., Ashton, L.J., Armstrong, B.K., Milne, E. (2015). Paternal dietary folate, B6 and B12 intake, and the risk of childhood brain tumors in Nutrition and Cancer, 67(2), 224-230. Available here.

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