Search

Introduction: Post cholecystectomy the common bile duct dilates in an effort to restore the storage function of gall bladder and helps in metabolism of lipids. There are many studies determining the association of abnormal lipid parameters with gall stones but there are not many studies comparing the diameter of CBD pre and post cholecystectomy and its clinical implication. Hence, under the light of above-mentioned data, we planned the present study to assess the effect of cholecystectomy on common bile duct diameter and lipid profile. Methodology: Patients with gall bladder stone eligible for cholecystectomy were included in the study. In this study pre and post operative cholecystectomy values of lipid profile and CBD diameter were compared. Patients were followed up till one year post operative to assess changes. Results: Out of total 55 cases included in the study 38.2% were male and 78.2% has mixed type of stone. Post operatively Serum cholesterol, triglyceride, HDL and LDL value improved significantly at the end of one year follow up (p<0.01). Pre operative mean CBD diameter was 4.38 mm which was increased to 5.6 mm at the end of one year post operatively (p<0.01) Conclusion: Cholecystectomy leads to significant impact on in lipid profile. Significant compensatory dilatation of common bile duct diameter occurs post cholecystectomy. This indicates a very positive impact of cholecystectomy on lipid profile. [ABSTRACT FROM AUTHOR]

Introduction: Resection of pancreatic tissue is necessary for many pancreatic diseases. The most common form of cancer, pancreatic duct adenocarcinoma, manifests with early metastases and is thought to be resistant to other currently known treatment regimens. Such tumors present a complex and difficult management and handling challenge for a surgeon. Surgical resection affords a better prognosis with a median survival of 14-20 months following resection and up to 25% 5-year survival rates. In this study, data from 75 pancreatic resections for diverse malignant pancreatic lesions will be presented. Methods: At a teaching institute in Central India, this ongoing longitudinal study began in 2009 and was carried on till 2018. Only 75 of the 122 patients who underwent pancreatic resection were deemed appropriate for the current study. All patients were thoroughly examined after being admitted before being given the option of surgery. There were 22 female patients and 53 male patients. The age range for the group was 34-67 years. Results from a range of different malignancies and various pancreatic resection procedures are presented in this study. Results: One of the most aggressive cancers, pancreatic adenocarcinoma, responds to surgical treatment better than other alternative techniques. Out of 75 patients in our series, 32 had pancreatic head cancer, 28 had periampullary cancer, 2 had duodenal cancer, 8 had distal cholangiocarcinoma, and 1 had mucin-producing cystadenocarcinoma. Four patients had pancreatic cancer in both the body and tail. Fifty-three men and 22 women, ages 34-67 years, Whipple's operation and distal pancreatectomy were the most frequent procedures. In our series, survival ranged from 18 to 24 months, and the 5-year survival rate was 12%, which is primarily seen with periampullary carcinoma. Conclusion: The sole option for long-term survival or a cure for pancreatic cancer is surgery. Chemoradiation is ineffective as a first line of treatment. However, some reports contend that palliative chemotherapy actually improves the quality of life. The biology of the illness rules and determines the result; the kind of surgery performed had no bearing on survival, morbidity, or fatality. Context: The above study was taken up in the context of - pancreatic tumors and pathological types, how imaging helps in deciding the plan of surgical management without biopsy. Outcomes of pancreatic resections for pancreatic cancer. Settings and Design: In a suburban hospital which is a tertiary care center, this longitudinal prospective study was conducted from 2009 to 2018. [ABSTRACT FROM AUTHOR]