1. Long-term results after PCI of unprotected distal left main coronary artery stenosis: the Bifurcations Bad Krozingen (BBK)-Left Main Registry
- Author
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Nikolaus Löffelhardt, Willibald Hochholzer, Kambis Mashayekhi, Thomas Comberg, Christian M. Valina, Michael Gick, Thomas G. Nührenberg, Franz-Josef Neumann, Nadja Banholzer, Aurel Toma, Miroslaw Ferenc, and Jürgen Rothe
- Subjects
Male ,medicine.medical_specialty ,Time Factors ,medicine.medical_treatment ,Left Main Coronary Artery Stenosis ,030204 cardiovascular system & hematology ,Coronary Angiography ,03 medical and health sciences ,Percutaneous Coronary Intervention ,0302 clinical medicine ,Restenosis ,Risk Factors ,Interquartile range ,Cause of Death ,Germany ,Internal medicine ,medicine ,Humans ,Registries ,cardiovascular diseases ,030212 general & internal medicine ,Myocardial infarction ,Aged ,Retrospective Studies ,business.industry ,Coronary Stenosis ,Percutaneous coronary intervention ,Drug-Eluting Stents ,General Medicine ,Prognosis ,equipment and supplies ,medicine.disease ,Coronary Vessels ,Survival Rate ,Stenosis ,Treatment Outcome ,surgical procedures, operative ,Conventional PCI ,Cardiology ,Female ,Cardiology and Cardiovascular Medicine ,business ,Mace ,Follow-Up Studies - Abstract
Percutaneous coronary intervention (PCI) of unprotected distal left main stenosis (UDLM) is increasingly performed as an alternative to surgical treatment. The optimal strategy for stenting in this setting is still a matter of debate. Therefore, this analysis investigated the long-term clinical outcome of a single- versus a double-stenting strategy for treatment of UDLM. From a large registry, 867 consecutive patients with UDLM undergoing either single or double stenting with drug-eluting stents (DES) were identified. Follow-up was up to 10 (median 3.1, interquartile range 1.1–5.3) years. Primary endpoint was MACE consisting of all-cause death, myocardial infarction, or target lesion re-intervention (TLR). Secondary clinical endpoints included these single endpoints and stent thrombosis. MACE occurred in 41.5% after single and in 49.0% after double stenting (P = 0.03). TLR was lower after single (17.4%) as compared to double stenting (27.2%; P
- Published
- 2018
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