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2. The first case report of emphysematous pyelonephritis and bacteremia due to Oligella urethralis.

Author

Yamaguchi H, Yamaguchi Y, Hadano Y, Hayashi K, Nagahara C, Muratani T, and Ohkusu K

Subjects
Aged, 80 and over, Alcaligenaceae classification, Alcaligenaceae drug effects, Alcaligenaceae genetics, Anti-Bacterial Agents pharmacology, Bacteremia microbiology, Blood microbiology, DNA, Bacterial chemistry, DNA, Bacterial genetics, DNA, Ribosomal chemistry, DNA, Ribosomal genetics, Drug Resistance, Bacterial, Female, Fluoroquinolones pharmacology, Gram-Negative Bacterial Infections microbiology, Humans, Long-Term Care, Pyelonephritis microbiology, RNA, Ribosomal, 16S genetics, Radiography, Abdominal, Sequence Analysis, DNA, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization, Tomography, X-Ray Computed, Urine microbiology, Alcaligenaceae isolation & purification, Bacteremia complications, Bacteremia diagnosis, Gram-Negative Bacterial Infections diagnosis, Pyelonephritis complications, Pyelonephritis diagnosis
Abstract

Oligella urethralis (O. urethralis) is an organism that rarely causes infections in humans. We report the case of a 90-year-old bedridden woman with progressive dementia who was placed in a long-term-care facility. She was admitted to our hospital due to fever and unconsciousness with pyuria. The abdominal computed tomography showed left pneumatosis and urinary stone. Fluoroquinolones-resistant O. urethralis, which was identified by the Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry (MALDI-TOF MS) and the 16S rRNA gene sequencing, was isolated form the blood and urine cultures at admission. To the best of our knowledge, this is the first case of emphysematous pyelonephritis caused by O. urethralis., (Copyright © 2017 Elsevier GmbH. All rights reserved.)

Published
2017
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3. Liver abscess caused by multidrug-resistant Pseudomonas aeruginosa treated with colistin; a case report and review of the literature.

Author

Yaita K, Sameshima I, Takeyama H, Matsuyama S, Nagahara C, Hashiguchi R, Moronaga Y, Tottori N, Komatsu M, Oshiro Y, and Yamaguchi Y

Subjects
Aged, Anti-Bacterial Agents administration & dosage, Anti-Bacterial Agents adverse effects, Anti-Bacterial Agents therapeutic use, Bacteremia drug therapy, Cephalosporins therapeutic use, Cholangitis complications, Cholangitis therapy, Colistin administration & dosage, Colistin adverse effects, Drug Resistance, Multiple, Bacterial, Humans, Kidney drug effects, Male, Microbial Sensitivity Tests, Penicillanic Acid analogs & derivatives, Penicillanic Acid therapeutic use, Piperacillin therapeutic use, Piperacillin, Tazobactam Drug Combination, Colistin therapeutic use, Liver Abscess, Pyogenic drug therapy, Liver Abscess, Pyogenic etiology, Pseudomonas Infections drug therapy, Pseudomonas Infections etiology, Pseudomonas aeruginosa drug effects
Abstract

A 77-year-old man had undergone left-lobe liver resection and a choledochojejunostomy six years previously, and thereafter he suffered from a postoperative relapse of cholangitis. He was admitted to our hospital due to liver abscesses and bacteremia caused by multidrug-resistant Pseudomonas aeruginosa. Empirical treatment with piperacillin/tazobactam was started, and the patient initially recovered. However, he developed a second case of sepsis caused by piperacillin/tazobactam-resistant P. aeruginosa bacteremia originating from a new liver abscess. We changed the piperacillin/tazobactam to colistin and flomoxef and continued the two antibiotics for one month. During the antibiotic therapy, the patient successfully underwent bile duct stent placement.

Published
2013
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