153 results on '"Nagamachi, Akiko"'
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2. DDX41 coordinates RNA splicing and transcriptional elongation to prevent DNA replication stress in hematopoietic cells
3. Application of prime editing system to introduce TP53 R248Q hotspot mutation in acute lymphoblastic leukemia cell line
4. UTX maintains the functional integrity of the murine hematopoietic system by globally regulating aging-associated genes
5. Acquired expression of CblQ367P in mice induces dysplastic myelopoiesis mimicking chronic myelomonocytic leukemia
6. Propagation of trimethylated H3K27 regulated by polycomb protein EED is required for embryogenesis, hematopoietic maintenance, and tumor suppression
7. Multiorgan failure with abnormal receptor metabolism in mice mimicking Samd9/9L syndromes
8. Fbxl10 overexpression in murine hematopoietic stem cells induces leukemia involving metabolic activation and upregulation of Nsg2
9. DDX41 coordinates RNA splicing and transcriptional elongation to prevent DNA replication stress in hematopoietic cells
10. Involvement of resistin-like molecule β in the development of methionine-choline deficient diet-induced non-alcoholic steatohepatitis in mice
11. Revertant somatic mosaicism as a cause of cancer
12. Association of aberrantASNSimprinting with asparaginase sensitivity and chromosomal abnormality in childhood BCP-ALL
13. Association between low doses of ionizing radiation, administered acutely or chronically, and time to onset of stroke in a rat model
14. Accumulation of versican facilitates wound healing: Implication of its initial ADAMTS-cleavage site
15. Effects of Radiation on Blood Pressure and Body Weight in the Spontaneously Hypertensive Rat Model. Are Radiation Effects on Blood Pressure Affected by Genetic Background?
16. Kinetics of cytokine receptor internalization under steady-state conditions affects growth of neighboring blood cells
17. Haploinsufficiency and acquired loss of Bcl11b and H2AX induces blast crisis of chronic myelogenous leukemia in a transgenic mouse model
18. A paralogous pair of mammalian host restriction factors form a critical host barrier against poxvirus infection
19. Association of aberrant ASNS imprinting with asparaginase sensitivity and chromosomal abnormality in childhood BCP-ALL
20. Association of aberrant ASNSimprinting with asparaginase sensitivity and chromosomal abnormality in childhood BCP-ALL
21. JMJD3 Plays Essential Roles in the Maintenance of Hematopoietic Stem Cells and Leukemic Stem Cells through the Regulation of p16INK4a
22. Impaired hematopoietic cell growth caused by the expression of P.R525H DDX41 mutation
23. Biological implications of somatic DDX41 p.R525H mutation in acute myeloid leukemia
24. Maintenance of the functional integrity of mouse hematopoiesis by EED and promotion of leukemogenesis by EED haploinsufficiency
25. Identification of cooperative genes for E2A‐PBX1 to develop acute lymphoblastic leukemia
26. Low Miki Expression in Myelodysplastic Syndromes Results in Polynuclear Cell Formation through Decondensation of Chromosomes in Prolonged Prometaphase
27. Defect in pre-ribosomal RNA processing is involved in myeloid leukemogenesis
28. Generation and Analysis of a Novel Mouse Model for Chronic Myelomonocytic Leukemia (CMML) with Acquired Expression of c-CBLQ367P
29. SETBP1 Mutations Drive Leukemic Transformation in ASXL1-Mutated MDS
30. Acquired Deficiency of A20 Results in Rapid Apoptosis, Systemic Inflammation, and Abnormal Hematopoietic Stem Cell Function
31. Haploinsufficiency Of SAMD9L, An Endosome Fusion Facilitator, In Mice Induces The Development Of Myeloid Malignancies Mimicking Human Diseases With Monosomy 7
32. Haploinsufficiency of SAMD9L, an Endosome Fusion Facilitator, Causes Myeloid Malignancies in Mice Mimicking Human Diseases with Monosomy 7
33. Haploinsufficiency of samd9L, encoding an endosome fusion facilitator, develops myeloid malignancies in mice mimicking human diseases with monosomy 7
34. Role of Pin1 Protein in the Pathogenesis of Nonalcoholic Steatohepatitis in a Rodent Model
35. Abnormal Mitosis Due to Impairment of Centrosome Maturation by the Deletion of Candidate 7q- Responsible Genes
36. Poly-ADP Ribosylation of Miki by tankyrase-1 Promotes Centrosome Maturation
37. Acquired expression of CblQ367Pin mice induces dysplastic myelopoiesis mimicking chronic myelomonocytic leukemia
38. Samd9L-Deficient Mice Develop Myeloid Malignancies Mimicking Human Diseases with Monosomy 7
39. The Dynactin Complex Maintains the Integrity of Metaphasic Centrosomes to Ensure Transition to Anaphase
40. Titan (Samd9L), a Candidate -7/7q- Responsible Gene Product, Downregulates Cytokine Signals by Facilitating Formation of Early Endosomes
41. A 5′ untranslated region containing the IRES element in the Runx1 gene is required for angiogenesis, hematopoiesis and leukemogenesis in a knock-in mouse model
42. Loss of Titan (Samd9L), a Candidate -7/7q- Responsible Gene Encoding An Actin Remodeling Regulator, Develops MDS/AML in Cooperation with Evi1 or Fbxl10.
43. Haploinsufficiency and acquired loss ofBcl11bandH2AXinduces blast crisis of chronic myelogenous leukemia in a transgenic mouse model
44. Identification of a common microdeletion cluster in 7q21.3 subband among patients with myeloid leukemia and myelodysplastic syndrome
45. Haploinsufficiency and Deficiency of a 7q Gene Titan (Samd9L) Predispose Leukemia Development in Cooperation with Deregulated Expression of a Transcription Factor, Evi1, or a Histone Demethylase, Fbxl10
46. Identification of Two 7q Genes Encoding Centrosomal Proteins as Myeloid Tumor-Suppressor Candidates.
47. Downregulation of a Candidate Myeloid Tumor Suppressor Gene Isolated from 7q21 Induces Abnormal Mitosis Due to Insufficient Centrosome Maturation.
48. Abnormal Mitosis and Genetic Instability Induced by Downregulation of Candidate Myeloid Tumor Suppressor Genes Isolated from the Long Arm of Chromosome 7.
49. Low MikiExpression in Myelodysplastic Syndromes Results in Polynuclear Cell Formation through Decondensation of Chromosomes in Prolonged Prometaphase
50. SETBP1Mutations Drive Leukemic Transformation in ASXL1-Mutated MDS
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