Search

Your search keyword '"Nagao, Takuya"' showing total 33 results
Start Over Author "Nagao, Takuya"
33 results on '"Nagao, Takuya"'

4. Aggressive and frequent resection of recurrences in retroperitoneal sarcoma contributes to long-term survival

Author

Komori, Koji, Tsukushi, Satoshi, Yoshida, Masahiro, Kinoshita, Takashi, Oshiro, Taihei, Ouch, Akira, Ito, Seiji, Abe, Tetsuya, Misawa, Kazunari, Ito, Yuichi, Natsume, Seiji, Higaki, Eiji, Okuno, Masataka, Hosoi, Takahiro, Shoji, Kawakatsu, Kunitomo, Aina, Oki, Satoshi, Suenaga, Yasuhito, Maeda, Shingo, Nagao, Takuya, Dei, Hideyuki, Numata, Yoshihisa, Aritake, Tsukasa, Tawada, Kakeru, and Shimizu, Yasuhiro

Published
2021
Full Text
View/download PDF

5. Clinical validation of the suppressive impact of letrozole on liver fibrosis in patients with breast cancer undergoing continuous letrozole administration: A retrospective study.

Author

Ohkawa, Kazuyoshi, Nakabori, Tasuku, Mukai, Kaori, Kozumi, Kazuhiro, Urabe, Makiko, Kai, Yugo, Takada, Ryoji, Ikezawa, Kenji, Yamaguchi, Yuko, Nagao, Takuya, Enomoto, Hatsune, Tachiki, Hidehisa, Higuchi, Ayako, Watanabe, Noriyuki, and Nakayama, Takahiro

Subjects
HEPATIC fibrosis, CANCER patients, BREAST cancer, LETROZOLE, ANASTROZOLE, ASPARTATE aminotransferase
Abstract

Treatment strategies for preventing liver fibrosis have not yet been established. Letrozole, widely used for breast cancer, has recently been reported to suppress liver fibrosis in murine models. Therefore, we aimed to validate the suppressive effects of letrozole on liver fibrosis in the clinical setting. From 2006 to 2020, 23 consecutive patients who received continuous letrozole treatment for 24 months or more and had a liver fibrosis marker FIB-4 index of ≥ 2.30, were included. Forty-three patients who underwent anastrozole treatment for 24 months or more and had a liver fibrosis marker FIB-4 index of ≥ 2.30, were also included as controls. The Fisher exact, chi-square, unpaired Student t, and paired Student t test were used to analyze the data. The patient characteristics were similar between the letrozole- and anastrozole-treated patient groups. Among the letrozole-treated patients, the mean FIB-4 index tended to decline during letrozole treatment; a significant decrease was observed at 18 and 24 months compared with the baseline values (p = 0.044 and p = 0.013). In addition, the mean aspartate aminotransferase-to-platelet ratio index (APRI) decreased during letrozole treatment; the values at 18 and 24 months were significantly lower than those at baseline (p = 0.024 and p = 0.026). In contrast, among anastrozole-treated patients, the mean FIB-4 index and APRI did not change during anastrozole treatment. When changes in the FIB-4 index were further examined in a limited number of patients with a FIB-4 index ≥ 2.67, a significant reduction in the FIB-4 index at 24 months compared with baseline was also observed in letrozole-treated patients (p = 0.023), but not in anastrozole-treated patients. In conclusion, our findings support a possible suppressive effect of letrozole on liver fibrosis in the clinical setting. Further studies are required to better understand the pharmacological effects of letrozole. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

13. Relationship between the level of sacral resection and short-term outcomes in patients undergoing total pelvic exenteration combined with sacral resection for rectal cancer

Author

Komori, Koji, primary, Tsukushi, Satoshi, additional, Yoshida, Masahiro, additional, Kinoshita, Takashi, additional, Sato, Yusuke, additional, Ouchi, Akira, additional, Ito, Seiji, additional, Abe, Tetsuya, additional, Misawa, Kazunari, additional, Ito, Yuichi, additional, Natsume, Seiji, additional, Higaki, Eiji, additional, Okuno, Masataka, additional, Fujieda, Hironori, additional, Kawakatsu, Shoji, additional, Kunitomo, Aina, additional, Oki, Satoshi, additional, Maeda, Shingo, additional, Nagao, Takuya, additional, Aritake, Tsukasa, additional, Tawada, Kakeru, additional, Akaza, Satoru, additional, and Shimizu, Yasuhiro, additional

Published
2022
Full Text
View/download PDF

14. Effect of Body Composition Change during Neoadjuvant Chemotherapy for Esophageal Squamous Cell Carcinoma

Author

Onishi, Sachiyo, primary, Tajika, Masahiro, additional, Tanaka, Tsutomu, additional, Yamada, Keisaku, additional, Kamiya, Tomoyasu, additional, Abe, Tetsuya, additional, Higaki, Eiji, additional, Fujieda, Hironori, additional, Nagao, Takuya, additional, Inaba, Yoshitaka, additional, Muro, Kei, additional, Shimizu, Masahito, additional, and Niwa, Yasumasa, additional

Published
2022
Full Text
View/download PDF

15. ASO Visual Abstract: Significance of Antimicrobial Prophylaxis for Prevention of Early-Onset Pneumonia after Radical Esophageal Cancer Resection: A Retrospective Analysis of 356 Patients Undergoing Thoracoscopic Esophagectomy

Author

Higaki, Eiji, primary, Abe, Tetsuya, additional, Fujieda, Hironori, additional, Hosoi, Takahiro, additional, Nagao, Takuya, additional, Komori, Koji, additional, Ito, Seiji, additional, Itoh, Naoya, additional, Matsuo, Keitaro, additional, and Shimizu, Yasuhiro, additional

Published
2021
Full Text
View/download PDF

16. Significance of Antimicrobial Prophylaxis for the Prevention of Early-Onset Pneumonia After Radical Esophageal Cancer Resection: A Retrospective Analysis of 356 Patients Undergoing Thoracoscopic Esophagectomy

Author

Higaki, Eiji, primary, Abe, Tetsuya, additional, Fujieda, Hironori, additional, Hosoi, Takahiro, additional, Nagao, Takuya, additional, Komori, Koji, additional, Ito, Seiji, additional, Itoh, Naoya, additional, Matsuo, Keitaro, additional, and Shimizu, Yasuhiro, additional

Published
2021
Full Text
View/download PDF

17. Should the Supraclavicular Lymph Nodes be Considered Regional Lymph Nodes in Cervical Esophageal Cancer?

Author

Numata, Yoshihisa, primary, Abe, Tetsuya, additional, Higaki, Eiji, additional, Hosoi, Takahiro, additional, Fujieda, Hironori, additional, Nagao, Takuya, additional, Hanai, Nobuhiro, additional, Suzuki, Hidenori, additional, Nishikawa, Daisuke, additional, Matsuo, Keitaro, additional, Fujii, Tsutomu, additional, and Shimizu, Yasuhiro, additional

Published
2021
Full Text
View/download PDF

21. Long-Term Outcome of Patients with Locally Advanced Clinically Unresectable Esophageal Cancer Undergoing Conversion Surgery after Induction Chemotherapy with Docetaxel Plus Cisplatin and 5-Fluorouracil

Author

Abe, Tetsuya, primary, Higaki, Eiji, additional, Hosoi, Takahiro, additional, Nagao, Takuya, additional, Bando, Hideaki, additional, Kadowaki, Shigenori, additional, Muro, Kei, additional, Tanaka, Tsutomu, additional, Tajika, Masahiro, additional, Niwa, Yasumasa, additional, and Shimizu, Yasuhiro, additional

Published
2020
Full Text
View/download PDF

22. Robot‐assisted enucleation of a giant submucosal tumor in the upper esophagus.

Author

Aritake, Tsukasa, Abe, Tetsuya, Higaki, Eiji, Nagao, Takuya, Hosoi, Takahiro, Hosoda, Waki, Sakamoto, Shoko, Ito, Seiji, Komori, Koji, and Shimizu, Yasuhiro

Subjects
ESOPHAGEAL tumors, SURGICAL margin, SURGICAL robots, NEEDLE biopsy, ENDOSCOPIC ultrasonography, LIPOSARCOMA, ESOPHAGEAL cancer
Abstract

Few reports have demonstrated robotic surgery for large tumors in the upper esophagus. We report a case of a 52‐year‐old woman with a giant submucosal tumor in the upper esophagus successfully enucleated using robotic surgery. She presented with odynophagia and dysphagia, with subsequent evaluation revealing a submucosal mass measuring approximately 10 cm in diameter in the upper esophagus. The mass was compressing the trachea and enlarged over 3 years. Endoscopic ultrasound fine needle aspiration of the tumor was non‐diagnostic. Robot‐assisted esophageal submucosal tumor enucleation was performed for diagnosis and treatment. Flexible forceps control allowed for a multi‐directional approach to dissect the tumor and stable forceps handling was critical in this delicate procedure. Subsequent pathological review revealed a well‐differentiated esophageal liposarcoma. While surgical margins were not entirely negative, the local recurrence rate of the tumor is low. At the patient's request, we decided to observe the patient without additional resection. [ABSTRACT FROM AUTHOR]

Published
2022
Full Text
View/download PDF

23. Surgical Strategy for Rectovaginal Fistula After Colorectal Anastomosis at a High-volume Cancer Center According to Image Type and Colonoscopy Findings

Author

KOMORI, KOJI, primary, KINOSHITA, TAKASHI, additional, OSHIRO, TAIHEI, additional, OUCHI, AKIRA, additional, ITO, SEIJI, additional, ABE, TETSUYA, additional, SENDA, YOSHIKI, additional, MISAWA, KAZUNARI, additional, ITO, YUICHI, additional, NATSUME, SEIJI, additional, HIGAKI, EIJI, additional, OKUNO, MASATAKA, additional, HOSOI, TAKAHIRO, additional, NAGAO, TAKUYA, additional, KUNITOMO, AINA, additional, OKI, SATOSHI, additional, TAKANO, JIN, additional, SUENAGA, YASUHITO, additional, MAEDA, SHINGO, additional, DEI, HIDEYUKI, additional, NUMATA, YOSHIHISA, additional, and SHIMIZU, YASUHIRO, additional

Published
2019
Full Text
View/download PDF

26. Gastric lymphangioma coexisting with mucosal gastric cancer: a rare case report.

Author

Matsushita, Aika, Yuasa, Norihiro, Miyake, Hideo, Nagai, Hidemasa, Nagao, Takuya, and Fujino, Masahiko

Abstract

We describe a case of gastric lymphangioma coexisting with mucosal gastric cancer. A 76-year-old man was diagnosed with an advanced gastric cancer (cT2N0M0, Stage I) presenting a nodular protruded lesion with irregular central depression. The surgically resected specimen showed a 4 × 3 cm sessile protruded lesion in the anterior wall of the lower stomach. Histopathological examination revealed a mucosal adenocarcinoma was located immediately above the lymphangioma and was elevated by the cystic component of lymphangioma without admixture, which suggested that the two components arose separately. The mucosal adenocarcinoma was masquerading as an advanced gastric cancer due to the protrusion by the lymphangioma. [ABSTRACT FROM AUTHOR]

Published
2020
Full Text
View/download PDF

28. Utility of human hepatocyte spheroids for evaluation of hepatotoxicity

Author

Ogihara, Takuo, primary, Iwai, Hisakazu, additional, Inoue, Yukiko, additional, Katagi, Jun, additional, Matsumoto, Norihito, additional, Motoi-Ohtsuji, Makiko, additional, Kakiki, Motoharu, additional, Kaneda, Shinya, additional, Nagao, Takuya, additional, Kusumoto, Kumiko, additional, Ozeki, Emiko, additional, Jomura, Tomoko, additional, Tanaka, Sho, additional, Ueda, Tadayoshi, additional, Ohta, Kunihiro, additional, Ohkura, Takako, additional, Arakawa, Hiroshi, additional, and Nagai, Daichi, additional

Published
2015
Full Text
View/download PDF

33. [Secondary Dementia Due to Leptomeningeal Metastasis of Breast Cancer Improved by Whole Brain Radiation].

Author

Asai M, Tanaka H, Goto Y, Yamada T, Yuasa N, Takeuchi E, Miyake H, Nagai H, Yoshioka Y, Okuno M, Kawai N, Minami T, Nagao T, Maeda S, Mouri K, Fukata K, Mizuno H, Iwase T, and Miyata K

Subjects
Brain Neoplasms diagnostic imaging, Brain Neoplasms secondary, Female, Humans, Magnetic Resonance Imaging, Meningeal Neoplasms diagnostic imaging, Meningeal Neoplasms secondary, Middle Aged, Brain Neoplasms radiotherapy, Breast Neoplasms pathology, Dementia etiology, Meningeal Neoplasms radiotherapy
Abstract

A 62-year-old woman received chemotherapy for breast cancer with bone metastasis and malignant pleural and pericardial effusion. She was examined by imaging for progressive cognitive impairment and headache. Enhanced MRI findings showed multiple solid tumors on brain surface, and brain perfusion scintigraphy showed blood flow decrease in both parietal lobes. She was diagnosed with secondary dementia due to leptomeningeal metastases of breast cancer, and whole brain external irradiation was performed(30 Gy/15 Fr). After treatment, multiple tumors were decreased in size and her cognitive impair- ment was improved.

Published
2017

Catalog

Books, media, physical & digital resources
See catalog results