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9. Supplementary Figure legend from SLFN11 is a BRCA Independent Biomarker for the Response to Platinum-Based Chemotherapy in High-Grade Serous Ovarian Cancer and Clear Cell Ovarian Carcinoma

Author

Akashi, Hidehiko, primary, Yachida, Nozomi, primary, Ueda, Haruka, primary, Yamaguchi, Manako, primary, Yamawaki, Kaoru, primary, Tamura, Ryo, primary, Suda, Kazuaki, primary, Ishiguro, Tatsuya, primary, Adachi, Sosuke, primary, Nagase, Yoshikazu, primary, Ueda, Yutaka, primary, Ueda, Masashi, primary, Abiko, Kaoru, primary, Kagabu, Masahiro, primary, Baba, Tsukasa, primary, Nakaoka, Hirofumi, primary, Enomoto, Takayuki, primary, Murai, Junko, primary, and Yoshihara, Kosuke, primary

Published
2024
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10. Supplementary Table 3 from SLFN11 is a BRCA Independent Biomarker for the Response to Platinum-Based Chemotherapy in High-Grade Serous Ovarian Cancer and Clear Cell Ovarian Carcinoma

Author

Akashi, Hidehiko, primary, Yachida, Nozomi, primary, Ueda, Haruka, primary, Yamaguchi, Manako, primary, Yamawaki, Kaoru, primary, Tamura, Ryo, primary, Suda, Kazuaki, primary, Ishiguro, Tatsuya, primary, Adachi, Sosuke, primary, Nagase, Yoshikazu, primary, Ueda, Yutaka, primary, Ueda, Masashi, primary, Abiko, Kaoru, primary, Kagabu, Masahiro, primary, Baba, Tsukasa, primary, Nakaoka, Hirofumi, primary, Enomoto, Takayuki, primary, Murai, Junko, primary, and Yoshihara, Kosuke, primary

Published
2024
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11. Supplementary Table 7 from SLFN11 is a BRCA Independent Biomarker for the Response to Platinum-Based Chemotherapy in High-Grade Serous Ovarian Cancer and Clear Cell Ovarian Carcinoma

Author

Akashi, Hidehiko, primary, Yachida, Nozomi, primary, Ueda, Haruka, primary, Yamaguchi, Manako, primary, Yamawaki, Kaoru, primary, Tamura, Ryo, primary, Suda, Kazuaki, primary, Ishiguro, Tatsuya, primary, Adachi, Sosuke, primary, Nagase, Yoshikazu, primary, Ueda, Yutaka, primary, Ueda, Masashi, primary, Abiko, Kaoru, primary, Kagabu, Masahiro, primary, Baba, Tsukasa, primary, Nakaoka, Hirofumi, primary, Enomoto, Takayuki, primary, Murai, Junko, primary, and Yoshihara, Kosuke, primary

Published
2024
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12. Supplementary Table 8 from SLFN11 is a BRCA Independent Biomarker for the Response to Platinum-Based Chemotherapy in High-Grade Serous Ovarian Cancer and Clear Cell Ovarian Carcinoma

Author

Akashi, Hidehiko, primary, Yachida, Nozomi, primary, Ueda, Haruka, primary, Yamaguchi, Manako, primary, Yamawaki, Kaoru, primary, Tamura, Ryo, primary, Suda, Kazuaki, primary, Ishiguro, Tatsuya, primary, Adachi, Sosuke, primary, Nagase, Yoshikazu, primary, Ueda, Yutaka, primary, Ueda, Masashi, primary, Abiko, Kaoru, primary, Kagabu, Masahiro, primary, Baba, Tsukasa, primary, Nakaoka, Hirofumi, primary, Enomoto, Takayuki, primary, Murai, Junko, primary, and Yoshihara, Kosuke, primary

Published
2024
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13. Supplementary Table 6 from SLFN11 is a BRCA Independent Biomarker for the Response to Platinum-Based Chemotherapy in High-Grade Serous Ovarian Cancer and Clear Cell Ovarian Carcinoma

Author

Akashi, Hidehiko, primary, Yachida, Nozomi, primary, Ueda, Haruka, primary, Yamaguchi, Manako, primary, Yamawaki, Kaoru, primary, Tamura, Ryo, primary, Suda, Kazuaki, primary, Ishiguro, Tatsuya, primary, Adachi, Sosuke, primary, Nagase, Yoshikazu, primary, Ueda, Yutaka, primary, Ueda, Masashi, primary, Abiko, Kaoru, primary, Kagabu, Masahiro, primary, Baba, Tsukasa, primary, Nakaoka, Hirofumi, primary, Enomoto, Takayuki, primary, Murai, Junko, primary, and Yoshihara, Kosuke, primary

Published
2024
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14. Data from SLFN11 is a BRCA Independent Biomarker for the Response to Platinum-Based Chemotherapy in High-Grade Serous Ovarian Cancer and Clear Cell Ovarian Carcinoma

Author

Akashi, Hidehiko, primary, Yachida, Nozomi, primary, Ueda, Haruka, primary, Yamaguchi, Manako, primary, Yamawaki, Kaoru, primary, Tamura, Ryo, primary, Suda, Kazuaki, primary, Ishiguro, Tatsuya, primary, Adachi, Sosuke, primary, Nagase, Yoshikazu, primary, Ueda, Yutaka, primary, Ueda, Masashi, primary, Abiko, Kaoru, primary, Kagabu, Masahiro, primary, Baba, Tsukasa, primary, Nakaoka, Hirofumi, primary, Enomoto, Takayuki, primary, Murai, Junko, primary, and Yoshihara, Kosuke, primary

Published
2024
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15. Supplementary Figure 2 from SLFN11 is a BRCA Independent Biomarker for the Response to Platinum-Based Chemotherapy in High-Grade Serous Ovarian Cancer and Clear Cell Ovarian Carcinoma

Author

Akashi, Hidehiko, primary, Yachida, Nozomi, primary, Ueda, Haruka, primary, Yamaguchi, Manako, primary, Yamawaki, Kaoru, primary, Tamura, Ryo, primary, Suda, Kazuaki, primary, Ishiguro, Tatsuya, primary, Adachi, Sosuke, primary, Nagase, Yoshikazu, primary, Ueda, Yutaka, primary, Ueda, Masashi, primary, Abiko, Kaoru, primary, Kagabu, Masahiro, primary, Baba, Tsukasa, primary, Nakaoka, Hirofumi, primary, Enomoto, Takayuki, primary, Murai, Junko, primary, and Yoshihara, Kosuke, primary

Published
2024
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16. Supplementary Table 9 from SLFN11 is a BRCA Independent Biomarker for the Response to Platinum-Based Chemotherapy in High-Grade Serous Ovarian Cancer and Clear Cell Ovarian Carcinoma

Author

Akashi, Hidehiko, primary, Yachida, Nozomi, primary, Ueda, Haruka, primary, Yamaguchi, Manako, primary, Yamawaki, Kaoru, primary, Tamura, Ryo, primary, Suda, Kazuaki, primary, Ishiguro, Tatsuya, primary, Adachi, Sosuke, primary, Nagase, Yoshikazu, primary, Ueda, Yutaka, primary, Ueda, Masashi, primary, Abiko, Kaoru, primary, Kagabu, Masahiro, primary, Baba, Tsukasa, primary, Nakaoka, Hirofumi, primary, Enomoto, Takayuki, primary, Murai, Junko, primary, and Yoshihara, Kosuke, primary

Published
2024
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17. Supplementary Table 4 from SLFN11 is a BRCA Independent Biomarker for the Response to Platinum-Based Chemotherapy in High-Grade Serous Ovarian Cancer and Clear Cell Ovarian Carcinoma

Author

Akashi, Hidehiko, primary, Yachida, Nozomi, primary, Ueda, Haruka, primary, Yamaguchi, Manako, primary, Yamawaki, Kaoru, primary, Tamura, Ryo, primary, Suda, Kazuaki, primary, Ishiguro, Tatsuya, primary, Adachi, Sosuke, primary, Nagase, Yoshikazu, primary, Ueda, Yutaka, primary, Ueda, Masashi, primary, Abiko, Kaoru, primary, Kagabu, Masahiro, primary, Baba, Tsukasa, primary, Nakaoka, Hirofumi, primary, Enomoto, Takayuki, primary, Murai, Junko, primary, and Yoshihara, Kosuke, primary

Published
2024
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18. Supplementary Table 5 from SLFN11 is a BRCA Independent Biomarker for the Response to Platinum-Based Chemotherapy in High-Grade Serous Ovarian Cancer and Clear Cell Ovarian Carcinoma

Author

Akashi, Hidehiko, primary, Yachida, Nozomi, primary, Ueda, Haruka, primary, Yamaguchi, Manako, primary, Yamawaki, Kaoru, primary, Tamura, Ryo, primary, Suda, Kazuaki, primary, Ishiguro, Tatsuya, primary, Adachi, Sosuke, primary, Nagase, Yoshikazu, primary, Ueda, Yutaka, primary, Ueda, Masashi, primary, Abiko, Kaoru, primary, Kagabu, Masahiro, primary, Baba, Tsukasa, primary, Nakaoka, Hirofumi, primary, Enomoto, Takayuki, primary, Murai, Junko, primary, and Yoshihara, Kosuke, primary

Published
2024
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19. Supplementary Table 1 from SLFN11 is a BRCA Independent Biomarker for the Response to Platinum-Based Chemotherapy in High-Grade Serous Ovarian Cancer and Clear Cell Ovarian Carcinoma

Author

Akashi, Hidehiko, primary, Yachida, Nozomi, primary, Ueda, Haruka, primary, Yamaguchi, Manako, primary, Yamawaki, Kaoru, primary, Tamura, Ryo, primary, Suda, Kazuaki, primary, Ishiguro, Tatsuya, primary, Adachi, Sosuke, primary, Nagase, Yoshikazu, primary, Ueda, Yutaka, primary, Ueda, Masashi, primary, Abiko, Kaoru, primary, Kagabu, Masahiro, primary, Baba, Tsukasa, primary, Nakaoka, Hirofumi, primary, Enomoto, Takayuki, primary, Murai, Junko, primary, and Yoshihara, Kosuke, primary

Published
2024
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20. Supplementary Figure 1 from SLFN11 is a BRCA Independent Biomarker for the Response to Platinum-Based Chemotherapy in High-Grade Serous Ovarian Cancer and Clear Cell Ovarian Carcinoma

Author

Akashi, Hidehiko, primary, Yachida, Nozomi, primary, Ueda, Haruka, primary, Yamaguchi, Manako, primary, Yamawaki, Kaoru, primary, Tamura, Ryo, primary, Suda, Kazuaki, primary, Ishiguro, Tatsuya, primary, Adachi, Sosuke, primary, Nagase, Yoshikazu, primary, Ueda, Yutaka, primary, Ueda, Masashi, primary, Abiko, Kaoru, primary, Kagabu, Masahiro, primary, Baba, Tsukasa, primary, Nakaoka, Hirofumi, primary, Enomoto, Takayuki, primary, Murai, Junko, primary, and Yoshihara, Kosuke, primary

Published
2024
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21. Supplementary Table 2 from SLFN11 is a BRCA Independent Biomarker for the Response to Platinum-Based Chemotherapy in High-Grade Serous Ovarian Cancer and Clear Cell Ovarian Carcinoma

Author

Akashi, Hidehiko, primary, Yachida, Nozomi, primary, Ueda, Haruka, primary, Yamaguchi, Manako, primary, Yamawaki, Kaoru, primary, Tamura, Ryo, primary, Suda, Kazuaki, primary, Ishiguro, Tatsuya, primary, Adachi, Sosuke, primary, Nagase, Yoshikazu, primary, Ueda, Yutaka, primary, Ueda, Masashi, primary, Abiko, Kaoru, primary, Kagabu, Masahiro, primary, Baba, Tsukasa, primary, Nakaoka, Hirofumi, primary, Enomoto, Takayuki, primary, Murai, Junko, primary, and Yoshihara, Kosuke, primary

Published
2024
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23. Tumor cell‐expressed lipolysis‐stimulated lipoprotein receptor negatively regulates T‐cell function

Author

Funauchi, Masashi, primary, Serada, Satoshi, additional, Hiramatsu, Kosuke, additional, Funajima, Eiji, additional, Kanda, Mizuki, additional, Nagase, Yoshikazu, additional, Nakagawa, Satoshi, additional, Ohkawara, Tomoharu, additional, Fujimoto, Minoru, additional, Suzuki, Yuji, additional, Ueda, Yutaka, additional, Kimura, Tadashi, additional, and Naka, Tetsuji, additional

Published
2023
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24. SLFN11 is a BRCA independent biomarker for the response to platinum-based chemotherapy in high-grade serous ovarian cancer and clear cell ovarian carcinoma

Author

Akashi, Hidehiko, primary, Yachida, Nozomi, additional, Ueda, Haruka, additional, Yamaguchi, Manako, additional, Yamawaki, Kaoru, additional, Tamura, Ryo, additional, Suda, Kazuaki, additional, Ishiguro, Tatsuya, additional, Adachi, Sosuke, additional, Nagase, Yoshikazu, additional, Ueda, Yutaka, additional, Ueda, Masashi, additional, Abiko, Kaoru, additional, Kagabu, Masahiro, additional, Baba, Tsukasa, additional, Nakaoka, Hirofumi, additional, Enomoto, Takayuki, additional, Murai, Junko, additional, and Yoshihara, Kosuke, additional

Published
2023
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27. Tumor cell‐expressed lipolysis‐stimulated lipoprotein receptor negatively regulates T‐cell function.

Author

Funauchi, Masashi, Serada, Satoshi, Hiramatsu, Kosuke, Funajima, Eiji, Kanda, Mizuki, Nagase, Yoshikazu, Nakagawa, Satoshi, Ohkawara, Tomoharu, Fujimoto, Minoru, Suzuki, Yuji, Ueda, Yutaka, Kimura, Tadashi, and Naka, Tetsuji

Subjects
LIPOPROTEIN receptors, IMMUNE checkpoint proteins, ANTIBODY-dependent cell cytotoxicity, T cells, IMMUNE checkpoint inhibitors
Abstract

Lipolysis‐stimulated lipoprotein receptor (LSR) is known as a lipoprotein receptor. LSR is expressed in various solid tumors, including epithelial ovarian, gastric, and colon cancers. High LSR expression is significantly associated with poor prognosis, but its role in cancer has not been fully elucidated. LSR belongs to the Ig protein superfamily, which is conserved in B7 family. Here, we assessed LSR as a novel immune checkpoint molecule. We developed a novel anti‐LSR antibody (#27‐6 mF‐18) that defects antibody‐dependent cellular cytotoxicity and complement‐dependent cytotoxicity activity. The #27‐6 mF‐18 cross‐reacts with both human and mouse LSR. We found that LSR was expressed on 4T1 murine breast cancer cell line. The #27‐6 mF‐18 exhibited antitumor effects against the 4T1 syngeneic tumor model, a poor immunogenic model refractory to treatment with anti‐PD‐1 or anti‐CTLA‐4 antibodies. Compared with control antibody‐treated mice, mice treated with #27‐6 mF‐18 showed significantly increased numbers of CD8+ T cells and a ratio of activated CD8+ T cells infiltrated in the tumor tissue. This antitumor effect was abrogated by CD8+ T‐cell depletion through anti‐CD8 antibody treatment, indicating that LSR negatively regulates tumor immunity by repressing CD8+ T cells. These findings show that LSR negatively regulates T‐cell immune activity. LSR targeting could provide immune checkpoint inhibitors for cancer immunotherapy. [ABSTRACT FROM AUTHOR]

Published
2024
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32. “Welcome to OBGYN World!” A novel recruitment event for medical students organized by the Japan Society of Obstetrics and Gynecology

Author

Miyake, Ryuta, primary, Komatsu, Hiroaki, additional, Ihira, Kei, additional, Hasegawa, Akihiro, additional, Maeda, Yuto, additional, Takemori, Satoshi, additional, Noguchi, Masashi, additional, Dofutsu, Mihoko, additional, Onodera, Yohei, additional, Shinagawa, Manaka, additional, Suemitsu, Tokumasa, additional, Sugita, Yosuke, additional, Higuchi, Yayoi, additional, Izaki, Nanae, additional, Kodera, Chisato, additional, Nagase, Yoshikazu, additional, Odawara, Kei, additional, Ogura, Junpei, additional, Osaku, Daiken, additional, Ohsuga, Takuma, additional, Enomoto, Naosuke, additional, Kanai, Takahiro, additional, Mishima, Sakurako, additional, Morita, Keiko, additional, Otsuka, Satoyo, additional, Suzuki, Kensuke, additional, Miura, Kiyonori, additional, and Yoshida, Yoshio, additional

Published
2022
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33. 2022-RA-1066-ESGO Metabolomics showed LSR promoted lipid metabolism in EOC

Author

Sakaguchi, Hitomi, primary, Hiramatsu, Kosuke, additional, Nagase, Yoshikazu, additional, Funauchi, Masashi, additional, Mamoru, Kakuda, additional, Nakagawa, Satoshi, additional, Miyoshi, Ai, additional, Kobayashi, Eiji, additional, Kimura, Toshihiro, additional, Ueda, Yutaka, additional, Naka, Tetsuji, additional, and Kimura, Tadashi, additional

Published
2022
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35. Assisted Reproductive Technique and Abnormal Cord Insertion: A Systematic Review and Meta-Analysis

Author

Matsuzaki, Shinya, primary, Ueda, Yutaka, additional, Matsuzaki, Satoko, additional, Nagase, Yoshikazu, additional, Kakuda, Mamoru, additional, Lee, Misooja, additional, Maeda, Michihide, additional, Kurahashi, Hiroki, additional, Hayashida, Harue, additional, Hisa, Tsuyoshi, additional, Mabuchi, Seiji, additional, and Kamiura, Shoji, additional

Published
2022
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45. "Welcome to OBGYN World!" A novel recruitment event for medical students organized by the Japan Society of Obstetrics and Gynecology.

Author

Miyake, Ryuta, Komatsu, Hiroaki, Ihira, Kei, Hasegawa, Akihiro, Maeda, Yuto, Takemori, Satoshi, Noguchi, Masashi, Dofutsu, Mihoko, Onodera, Yohei, Shinagawa, Manaka, Suemitsu, Tokumasa, Sugita, Yosuke, Higuchi, Yayoi, Izaki, Nanae, Kodera, Chisato, Nagase, Yoshikazu, Odawara, Kei, Ogura, Junpei, Osaku, Daiken, and Ohsuga, Takuma

Subjects
COVID-19, MEDICAL students, GYNECOLOGY, OBSTETRICS, QUESTIONNAIRES, DESCRIPTIVE statistics
Abstract

"Welcome to OBGYN World!" A novel recruitment event for medical students organized by the Japan Society of Obstetrics and Gynecology. Since 2012, the number of doctors in Japan who specialize in obstetrics and gynecology has shown a decreasing trend. To increase the number of doctors majoring in obstetrics and gynecology, the Japanese Trainees in Obstetrics and Gynecology subcommittee developed a new recruitment event called Welcome to OBGYN World! (WOW!); the aim of this event was to focus on lower grades of medical students. The present report describes the content of WOW! and the results of a post‐event questionnaire administered to participating students and tutors. WOW! was held online in order to avoid the risk of Coronavirus Disease 2019 infection for participants. Sixty of the 82 medical schools nationwide (73.2%) participated in this event. Overall, there were 285 participating students, ranging from first to fourth grade in medical school, and 106 tutors were involved to teach material at the event. In the post‐event questionnaire survey, 97.6% (248/254) and 100% of the participants stated they now had a high degree of interest in obstetrics and gynecology and found the specialty attractive, respectively. Furthermore, 93.6% (90/94) of the tutors stated that WOW! had helped recruitment activities in their universities. Based on this outcome, members of the Japanese Trainees of Obstetrics and Gynecology subcommittee will now try to increase the number of doctors specializing in obstetrics and gynecology by holding WOW! annually. [ABSTRACT FROM AUTHOR]

Published
2023
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48. Additional file 5 of Placenta previa with posterior extrauterine adhesion: clinical features and management practice

Author

Nagase, Yoshikazu, Matsuzaki, Shinya, Endo, Masayuki, Takeya Hara, Okada, Aiko, Mimura, Kazuya, Hiramatsu, Kosuke, Kakigano, Aiko, Nakatsuka, Erika, Miyake, Tatsuya, Takiuchi, Tsuyoshi, Ueda, Yutaka, Tomimatsu, Takuji, and Kimura, Tadashi

Subjects
embryonic structures, sense organs, skin and connective tissue diseases
Abstract

Additional file 5: Table S2. Patient characteristics of placenta previa with posterior extrauterine adhesion before and after practice change.

Published
2021
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49. Additional file of Placenta previa with posterior extrauterine adhesion: clinical features and management practice

Author

Nagase, Yoshikazu, Matsuzaki, Shinya, Endo, Masayuki, Takeya Hara, Okada, Aiko, Mimura, Kazuya, Hiramatsu, Kosuke, Kakigano, Aiko, Nakatsuka, Erika, Miyake, Tatsuya, Takiuchi, Tsuyoshi, Ueda, Yutaka, Tomimatsu, Takuji, and Kimura, Tadashi

Subjects
embryonic structures, reproductive and urinary physiology
Abstract

Additional file of Placenta previa with posterior extrauterine adhesion: clinical features and management practice

Published
2021
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50. Additional file 6 of Placenta previa with posterior extrauterine adhesion: clinical features and management practice

Author

Nagase, Yoshikazu, Matsuzaki, Shinya, Endo, Masayuki, Takeya Hara, Okada, Aiko, Mimura, Kazuya, Hiramatsu, Kosuke, Kakigano, Aiko, Nakatsuka, Erika, Miyake, Tatsuya, Takiuchi, Tsuyoshi, Ueda, Yutaka, Tomimatsu, Takuji, and Kimura, Tadashi

Abstract

Additional file 6: Table S3. The estimated reasons for posterior extrauterine adhesion.

Published
2021
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