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159 results on '"Nagata Yoshihiko"'

2. The effect of an external magnetic force on cell adhesion and proliferation of magnetically labeled mesenchymal stem cells

Author

Nakamae Toshio, Adachi Nobuo, Kobayashi Takaaki, Nagata Yoshihiko, Nakasa Tomoyuki, Tanaka Nobuhiro, and Ochi Mitsuo

Subjects
Sports medicine, RC1200-1245
Abstract

Abstract Background As the strategy for tissue regeneration using mesenchymal stem cells (MSCs) for transplantation, it is necessary that MSCs be accumulated and kept in the target area. To accumulate MSCs effectively, we developed a novel technique for a magnetic targeting system with magnetically labeled MSCs and an external magnetic force. In this study, we examined the effect of an external magnetic force on magnetically labeled MSCs in terms of cell adhesion and proliferation. Methods Magnetically labeled MSCs were plated at the bottom of an insert under the influence of an external magnetic force for 1 hour. Then the inserts were turned upside down for between 1 and 24 hours, and the number of MSCs which had fallen from the membrane was counted. The gene expression of MSCs affected magnetic force was analyzed with microarray. In the control group, the same procedure was done without the external magnetic force. Results At 1 hour after the inserts were turned upside down, the average number of fallen MSCs in the magnetic group was significantly smaller than that in the control group, indicating enhanced cell adhesion. At 24 hours, the average number of fallen MSCs in the magnetic group was also significantly smaller than that in control group. In the magnetic group, integrin alpha2, alpha6, beta3 BP, intercellular adhesion molecule-2 (ICAM-2), platelet/endothelial cell adhesion molecule-1 (PECAM-1) were upregulated. At 1, 2 and 3 weeks after incubation, there was no statistical significant difference in the numbers of MSCs in the magnetic group and control group. Conclusions The results indicate that an external magnetic force for 1 hour enhances cell adhesion of MSCs. Moreover, there is no difference in cell proliferation after using an external magnetic force on magnetically labeled MSCs.

Published
2010
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4. Generalizations of Ho-Lee's binomial interest rate model I: from one- to multi-factor

Author

Akahori, Jirô, Aoki, Hiroki, and Nagata, Yoshihiko

Subjects
Mathematics - Probability, Quantitative Finance - Pricing of Securities, 91B28, 60G50
Abstract

In this paper a multi-factor generalization of Ho-Lee model is proposed. In sharp contrast to the classical Ho-Lee, this generalization allows for those movements other than parallel shifts, while it still is described by a recombining tree, and is stationary to be compatible with principal component analysis. Based on the model, generalizations of duration-based hedging are proposed. A continuous-time limit of the model is also discussed., Comment: 34 pages, 3 figures

Published
2006

10. Tendon-Bone Insertion Repair and Regeneration Using Polyglycolic Acid Sheet in the Rabbit Rotator Cuff Injury Model

Author

Yokoya, Shin, Mochizuki, Yu, Nagata, Yoshihiko, Deie, Masataka, and Ochi, Mitsuo

Subjects
Rotator cuff (Anatomy) -- Injuries -- Physiological aspects -- Medical examination -- Methods -- Research -- Health aspects, Tissue engineering -- Physiological aspects -- Methods -- Research -- Health aspects, Thermoplastics -- Health aspects -- Physiological aspects -- Research -- Methods, Rotator cuff repair -- Health aspects -- Physiological aspects -- Research -- Methods, Health, Sports and fitness, Physiological aspects, Medical examination, Research, Injuries, Methods, Health aspects
Abstract

Byline: Shin Yokoya, MD (Department of Orthopaedic Surgery, Programs for Applied Biomedicine, Division of Clinical Medical Science, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan); Yu Mochizuki, MD, PhD [...]

Published
2008
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19. Analysis of excitation and coherent amplitude enhancement of surface acoustic waves by the phase velocity scanning method.

Author

Yamanaka, Kazushi, Kolosov, O. V., Nagata, Yoshihiko, Koda, Toshio, Nishino, Hideo, and Tsukahara, Yusuke

Subjects
ACOUSTIC surface waves, ELECTRONIC excitation, SCATTERING amplitude (Physics)
Abstract

Presents an analysis of excitation and coherent amplitude enhancement of surface acoustic waves (SAW) generated by phase velocity scanning method. Details of a theoretical formulation for the characteristics of surface acoustic waves; Characteristics of the amplitude of the SAW; Factor that affects SAW frequency.

Published
1993
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24. Generalizations of Ho-Lee's binomial interest rate model I: from one- to multi-factor

Author

Akahori, Jir��, Aoki, Hiroki, and Nagata, Yoshihiko

Subjects
FOS: Economics and business, 60G50, 91B28, Probability (math.PR), FOS: Mathematics, Pricing of Securities (q-fin.PR), Quantitative Finance - Pricing of Securities, Mathematics - Probability
Abstract

In this paper a multi-factor generalization of Ho-Lee model is proposed. In sharp contrast to the classical Ho-Lee, this generalization allows for those movements other than parallel shifts, while it still is described by a recombining tree, and is stationary to be compatible with principal component analysis. Based on the model, generalizations of duration-based hedging are proposed. A continuous-time limit of the model is also discussed., 34 pages, 3 figures

Published
2006

28. Evaluation of Heart Rate Variability by Using Wavelet Transform and a Recurrent Neural Network

Author

NATIONAL INST OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY IBARAKI (JAPAN), Fukuda, Osamu, Nagata, Yoshihiko, Homma, Keiko, Tsuji, Toshio, NATIONAL INST OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY IBARAKI (JAPAN), Fukuda, Osamu, Nagata, Yoshihiko, Homma, Keiko, and Tsuji, Toshio

Abstract

The purpose of this paper is to evaluate the physical and mental stress based on the physiological index, and a new evaluation method of heart rate variability is proposed. This method combines the wavelet transform with a recurrent neural network. The features of the proposed method are as follows: 1. The wavelet transform is utilized for the feature extraction so that the local change of heart rate variability in the time-frequency domain can be extracted 2. In order to learn and evaluate the different patterns of heart rate variability caused by individual variations, body conditions, circadian rhythms and so on, a new recurrent neural network which incorporates a hidden Markov Model is used in the experiments, a mental workload was given to five subjects, and the subjective rating scores of their mental stress were evaluated using heart rate variability. It was confirmed from the experiments that the proposed method could achieve high learning/evaluating performances., Papers from 23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, October 25-26, 2001 held in Istanbul, Turkey. See also ADM001351 for entire conference on cd-rom.

Published
2001

39. Acoustic Imaging of Plate Thickness and Sound Velocity during Tensile Testing at Low Temperature

Author

Sato, Harumichi, Kolosov, Oleg, Nagata, Yoshihiko, Koda, Toshio, Yamanaka, Kazushi, Sato, Harumichi, Kolosov, Oleg, Nagata, Yoshihiko, Koda, Toshio, and Yamanaka, Kazushi

Abstract

In many procedures important in engineering and science, such as plastic working, tensile, bending, creep and fatigue tests, both the geometrical shape and material properties of objects change simultaneously. Therefore, simultaneous measurement of these quantities has been sought. In this paper we present a novel method for simultaneous imaging of the thickness of and sound velocity in a plate. After evaluating the accuracy of this method in a low-temperature acoustic microscope, it was applied to a stainless steel plate that underwent the stress-induced martensitic transformation, and thickness and sound velocity images around a notch in the plate were obtained. Since the thickness and velocity images differ slightly, the possibility of independent but simultaneous imaging of plate thickness and sound velocity was confirmed.

Published
1994

48. Residual strains and disorder in ZnSSe epitaxial films on GaAs

Author

Kanemitsu, Yoshihiko, primary, Yamamoto, Aishi, additional, Matsue, Hitoshi, additional, Nabeta, Hiroyuki, additional, Masumoto, Yasuaki, additional, Yamaga, Shigeki, additional, Yoshikawa, Akihiko, additional, Yamanaka, Kazushi, additional, Nagata, Yoshihiko, additional, and Koda, Toshio, additional

Published
1992
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