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To investigate the correlation of prostatic parameters of transrectal ultrasonography with age in patients with benign prostatic hyperplasia (BPH) and the patterns of prostatic enlargement in different age groups of the patients.We retrospectively studied the reports of transrectal ultrasonography for 1 739 outpatients with BPH from January 2010 to December 2015, who were divided into four age groups, 50－59, 60－69, 70－79, and =≥80 years. We analyzed the patterns of prostatic enlargement in different age groups.The transrectal ultrasonographic prostatic parameters, most significantly the transitional zone index (TZI), of the BPH patients were positively correlated with age. And the prostatic parameters were gradually increased with aging, with statistically significant differences among different age groups (P0.05). The prostate was enlarged most quickly between 50 and 69 years of age.There is a positive correlation between age and prostatic parameters of transrectal ultrasonography, particularly the transitional zone index, in patients with BPH, which indicates that TZI can serve as one of the best criteria in evaluating BPH. The volume of the prostate, especially that of the transitional zone, is increased with aging, reaching the peak between 50 and 69 years, which is of great significance for further study of the development and progression of BPH.目的： 分析良性前列腺增生(BPH)患者直肠法超声测定前列腺参数（前列腺体积、移行带体积、移行带指数）与年龄的相关性，同时比较不同年龄人群的前列腺增长规律。 方法： 收集2010年1月至2015年12月在门诊就诊的BPH患者，并且行直肠法超声检查1 739例，按年龄分为4组（50~59，60~69,70~79, =≥80岁），分析不同年龄人群的BPH规律。 结果： 该人群中各超声测定参数与年龄的增长呈正相关，以移行带指数和年龄的相关性最大。而且研究还发现，随着年龄增长，各组间超声测定参数是在逐渐增大，差异有显著性（P0.05），并且提示在50~69岁之间前列腺增长速度最快。 结论： 该人群中，各超声测定参数和年龄的相关性较好，其中以移行带指数和年龄的相关性最好，移行带指数可作为临床研究BPH规律的最佳指标之一。同时随着年龄的增长，前列腺体积逐渐增大，并且以移行带体积增大更为迅速，而且还提示50~69岁是前列腺体积增长变化的高峰期，这对于更加深入研究BPH的发生和进展意义重大。.

There is a great clinical need for biodegradable materials, which were used as pins of circular staplers, for gastrointestinal reconstruction in medicine. In this work we compared the effects of the Mg–6Zn and the titanium alloys on collagen metabolism in the healing of the intestinal tract in vivo. The study included Sprague-Dawley rats and their effect was compared on rat’s intestinal tract, using serum magnesium, radiology, and immunohistochemistry in vivo. Radiographic and scanning electron microscope evaluation confirmed the degradation by Mg–6Zn alloy during the implantation period. Biochemical measurements including serum magnesium, creatinine, blood urea nitrogen and glutamic–pyruvic–transaminase proved that degradation of Mg–6Zn alloy showed no impact on serum magnesium and the function of other important organs. Superior to titanium alloy, Mg–6Zn alloy enhanced the expression of collagen I/III and relatively suppressed the expression of MMP-1/-13 in the healing tissues, leading to more mature collagen formation at the site of anastomosis. In conclusion, Mg–6Zn alloy performed better than titanium alloy on collagen metabolism and promoted the healing of intestinal anastomosis. Hence, Mg-6Zn may be a promising candidate for use of stapler pins for intestinal reconstruction in the clinically.