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We present Zillow Indoor Dataset (ZInD): A large indoor dataset with 71,474 panoramas from 1,524 real unfurnished homes. ZInD provides annotations of 3D room layouts, 2D and 3D floor plans, panorama location in the floor plan, and locations of windows and doors. The ground truth construction took over 1,500 hours of annotation work. To the best of our knowledge, ZInD is the largest real dataset with layout annotations. A unique property is the room layout data, which follows a real world distribution (cuboid, more general Manhattan, and non-Manhattan layouts) as opposed to the mostly cuboid or Manhattan layouts in current publicly available datasets. Also, the scale and annotations provided are valuable for effective research related to room layout and floor plan analysis. To demonstrate ZInD’s benefits, we benchmark on room layout estimation from single panoramas and multi-view registration.

Adversarial learning has been proven to be effective for capturing long-range and high-level label consistencies in semantic segmentation. Unique to medical imaging, capturing 3D semantics in an effective yet computationally efficient way remains an open problem. In this study, we address this computational burden by proposing a novel projective adversarial network, called PAN, which incorporates high-level 3D information through 2D projections. Furthermore, we introduce an attention module into our framework that helps for a selective integration of global information directly from our segmentor to our adversarial network. For the clinical application we chose pancreas segmentation from CT scans. Our proposed framework achieved state-of-the-art performance without adding to the complexity of the segmentor., Accepted for presentation in MICCAI 2019

Early detection of lung nodules is of great importance in lung cancer screening. Existing research recognizes the critical role played by CAD systems in early detection and diagnosis of lung nodules. However, many CAD systems, which are used as cancer detection tools, produce a lot of false positives (FP) and require a further FP reduction step. Furthermore, guidelines for early diagnosis and treatment of lung cancer are consist of different shape and volume measurements of abnormalities. Segmentation is at the heart of our understanding of nodules morphology making it a major area of interest within the field of computer aided diagnosis systems. This study set out to test the hypothesis that joint learning of false positive (FP) nodule reduction and nodule segmentation can improve the computer aided diagnosis (CAD) systems' performance on both tasks. To support this hypothesis we propose a 3D deep multi-task CNN to tackle these two problems jointly. We tested our system on LUNA16 dataset and achieved an average dice similarity coefficient (DSC) of 91% as segmentation accuracy and a score of nearly 92% for FP reduction. As a proof of our hypothesis, we showed improvements of segmentation and FP reduction tasks over two baselines. Our results support that joint training of these two tasks through a multi-task learning approach improves system performance on both. We also showed that a semi-supervised approach can be used to overcome the limitation of lack of labeled data for the 3D segmentation task., Accepted for publication at IEEE EMBC (40th International Engineering in Medicine and Biology Conference)

Deep learning has demonstrated tremendous revolutionary changes in the computing industry and its effects in radiology and imaging sciences have begun to dramatically change screening paradigms. Specifically, these advances have influenced the development of computer-aided detection and diagnosis (CAD) systems. These technologies have long been thought of as “second-opinion” tools for radiologists and clinicians. However, with significant improvements in deep neural networks, the diagnostic capabilities of learning algorithms are approaching levels of human expertise (radiologists, clinicians etc.), shifting the CAD paradigm from a “second opinion” tool to a more collaborative utility. This paper reviews recently developed CAD systems based on deep learning technologies for breast cancer diagnosis, explains their superiorities with respect to previously established systems, defines the methodologies behind the improved achievements including algorithmic developments, and describes remaining challenges in breast cancer screening and diagnosis. We also discuss possible future directions for new CAD models that continue to change as artificial intelligence algorithms evolve.

There are at least two categories of errors in radiology screening that can lead to suboptimal diagnostic decisions and interventions:(i)human fallibility and (ii)complexity of visual search. Computer aided diagnostic (CAD) tools are developed to help radiologists to compensate for some of these errors. However, despite their significant improvements over conventional screening strategies, most CAD systems do not go beyond their use as second opinion tools due to producing a high number of false positives, which human interpreters need to correct. In parallel with efforts in computerized analysis of radiology scans, several researchers have examined behaviors of radiologists while screening medical images to better understand how and why they miss tumors, how they interact with the information in an image, and how they search for unknown pathology in the images. Eye-tracking tools have been instrumental in exploring answers to these fundamental questions. In this paper, we aim to develop a paradigm shift CAD system, called collaborative CAD (C-CAD), that unifies both of the above mentioned research lines: CAD and eye-tracking. We design an eye-tracking interface providing radiologists with a real radiology reading room experience. Then, we propose a novel algorithm that unifies eye-tracking data and a CAD system. Specifically, we present a new graph based clustering and sparsification algorithm to transform eye-tracking data (gaze) into a signal model to interpret gaze patterns quantitatively and qualitatively. The proposed C-CAD collaborates with radiologists via eye-tracking technology and helps them to improve diagnostic decisions. The C-CAD learns radiologists' search efficiency by processing their gaze patterns. To do this, the C-CAD uses a deep learning algorithm in a newly designed multi-task learning platform to segment and diagnose cancers simultaneously., Submitted to Medical Image Analysis Journal (MedIA)