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1. Study on the Actual Situation of Entrances and Exits of Underground Stations Installed on Building Sites and the Application of Urban Development Systems

Author

Nakamura, Hideo, Murakami, Kiyonori, Kikuchi, Masahiko, Oosawa, Masaharu, di Prisco, Marco, Series Editor, Chen, Sheng-Hong, Series Editor, Vayas, Ioannis, Series Editor, Kumar Shukla, Sanjay, Series Editor, Sharma, Anuj, Series Editor, Kumar, Nagesh, Series Editor, Wang, Chien Ming, Series Editor, Cui, Zhen-Dong, Series Editor, Wu, Wei, editor, Leung, Chun Fai, editor, Zhou, Yingxin, editor, and Li, Xiaozhao, editor

Published
2024
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4. Clinicopathologic analysis of pineal parenchymal tumors of intermediate differentiation: a multi-institutional cohort study by the Kyushu Neuro-Oncology Study Group

Author

Yamashita, Shinji, Takeshima, Hideo, Hata, Nobuhiro, Uchida, Hiroyuki, Shinojima, Naoki, Yokogami, Kiyotaka, Nakano, Yoshiteru, Sakata, Kiyohiko, Fudaba, Hirotaka, Enomoto, Toshiyuki, Nakahara, Yukiko, Ujifuku, Kenta, Sugawara, Kenichi, Iwaki, Tooru, Sangatsuda, Yuhei, Yoshimoto, Koji, Hanaya, Ryousuke, Mukasa, Akitake, Suzuki, Kohei, Yamamoto, Junkoh, Negoto, Tetsuya, Nakamura, Hideo, Momii, Yasutomo, Fujiki, Minoru, Abe, Hiroshi, Masuoka, Jun, Abe, Tatsuya, Matsuo, Takayuki, and Ishiuchi, Shogo

Published
2023
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5. Analysis of Changes Before, During, and After Simulated Postoperative Delirium Experience Using VR for Clinical Nurses

Author

Matsuura, Jumpei, Kunii, Takahiro, Noborio, Hiroshi, Onishi, Katsuhiko, Nakamura, Hideo, Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Yung, Moti, Editorial Board Member, and Kurosu, Masaaki, editor

Published
2022
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7. A C19MC-LIN28A-MYCN Oncogenic Circuit Driven by Hijacked Super-enhancers Is a Distinct Therapeutic Vulnerability in ETMRs: A Lethal Brain Tumor

Author

Sin-Chan, Patrick, Mumal, Iqra, Suwal, Tannu, Ho, Ben, Fan, Xiaolian, Singh, Irtisha, Du, Yuchen, Lu, Mei, Patel, Neilket, Torchia, Jonathon, Popovski, Dean, Fouladi, Maryam, Guilhamon, Paul, Hansford, Jordan R, Leary, Sarah, Hoffman, Lindsey M, Levy, Jean M Mulcahy, Lassaletta, Alvaro, Solano-Paez, Palma, Rivas, Eloy, Reddy, Alyssa, Gillespie, G Yancey, Gupta, Nalin, Van Meter, Timothy E, Nakamura, Hideo, Wong, Tai-Tong, Ra, Young-Shin, Kim, Seung-Ki, Massimi, Luca, Grundy, Richard G, Fangusaro, Jason, Johnston, Donna, Chan, Jennifer, Lafay-Cousin, Lucie, Hwang, Eugene I, Wang, Yin, Catchpoole, Daniel, Michaud, Jean, Ellezam, Benjamin, Ramanujachar, Ramya, Lindsay, Holly, Taylor, Michael D, Hawkins, Cynthia E, Bouffet, Eric, Jabado, Nada, Singh, Sheila K, Kleinman, Claudia L, Barsyte-Lovejoy, Dalia, Li, Xiao-Nan, Dirks, Peter B, Lin, Charles Y, Mack, Stephen C, Rich, Jeremy N, and Huang, Annie

Subjects
Rare Diseases, Neurosciences, Cancer, Genetics, Biotechnology, 5.1 Pharmaceuticals, Development of treatments and therapeutic interventions, Biomarkers, Tumor, Brain Neoplasms, Cell Cycle, Cell Transformation, Neoplastic, Chromosomes, Human, Pair 19, Chromosomes, Human, Pair 2, DNA Copy Number Variations, Enhancer Elements, Genetic, Epigenesis, Genetic, Gene Expression Regulation, Gene Regulatory Networks, Genetic Association Studies, Genetic Predisposition to Disease, Humans, MicroRNAs, Models, Biological, Multigene Family, N-Myc Proto-Oncogene Protein, Neoplasms, Germ Cell and Embryonal, Oncogenes, RNA-Binding Proteins, C19MC, ETMR, LIN28A, MYCN, brain tumor, cell-cycle, epigenetics, microRNA, super-enhancer, therapeutics, Oncology and Carcinogenesis, Oncology & Carcinogenesis
Abstract

Embryonal tumors with multilayered rosettes (ETMRs) are highly lethal infant brain cancers with characteristic amplification of Chr19q13.41 miRNA cluster (C19MC) and enrichment of pluripotency factor LIN28A. Here we investigated C19MC oncogenic mechanisms and discovered a C19MC-LIN28A-MYCN circuit fueled by multiple complex regulatory loops including an MYCN core transcriptional network and super-enhancers resulting from long-range MYCN DNA interactions and C19MC gene fusions. Our data show that this powerful oncogenic circuit, which entraps an early neural lineage network, is potently abrogated by bromodomain inhibitor JQ1, leading to ETMR cell death.

Published
2019

9. Development of a VR/HMD System for Simulating Several Scenarios of Post-Operative Delirium

Author

Matsuura, Jumpei, Kunii, Takahiro, Noborio, Hiroshi, Watanabe, Kaoru, Onishi, Katsuhiko, Nakamura, Hideo, Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Woeginger, Gerhard, Editorial Board Member, Yung, Moti, Editorial Board Member, and Kurosu, Masaaki, editor

Published
2021
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11. Intertumoral Heterogeneity within Medulloblastoma Subgroups

Author

Cavalli, Florence MG, Remke, Marc, Rampasek, Ladislav, Peacock, John, Shih, David JH, Luu, Betty, Garzia, Livia, Torchia, Jonathon, Nor, Carolina, Morrissy, A Sorana, Agnihotri, Sameer, Thompson, Yuan Yao, Kuzan-Fischer, Claudia M, Farooq, Hamza, Isaev, Keren, Daniels, Craig, Cho, Byung-Kyu, Kim, Seung-Ki, Wang, Kyu-Chang, Lee, Ji Yeoun, Grajkowska, Wieslawa A, Perek-Polnik, Marta, Vasiljevic, Alexandre, Faure-Conter, Cecile, Jouvet, Anne, Giannini, Caterina, Rao, Amulya A Nageswara, Li, Kay Ka Wai, Ng, Ho-Keung, Eberhart, Charles G, Pollack, Ian F, Hamilton, Ronald L, Gillespie, G Yancey, Olson, James M, Leary, Sarah, Weiss, William A, Lach, Boleslaw, Chambless, Lola B, Thompson, Reid C, Cooper, Michael K, Vibhakar, Rajeev, Hauser, Peter, van Veelen, Marie-Lise C, Kros, Johan M, French, Pim J, Ra, Young Shin, Kumabe, Toshihiro, López-Aguilar, Enrique, Zitterbart, Karel, Sterba, Jaroslav, Finocchiaro, Gaetano, Massimino, Maura, Van Meir, Erwin G, Osuka, Satoru, Shofuda, Tomoko, Klekner, Almos, Zollo, Massimo, Leonard, Jeffrey R, Rubin, Joshua B, Jabado, Nada, Albrecht, Steffen, Mora, Jaume, Van Meter, Timothy E, Jung, Shin, Moore, Andrew S, Hallahan, Andrew R, Chan, Jennifer A, Tirapelli, Daniela PC, Carlotti, Carlos G, Fouladi, Maryam, Pimentel, José, Faria, Claudia C, Saad, Ali G, Massimi, Luca, Liau, Linda M, Wheeler, Helen, Nakamura, Hideo, Elbabaa, Samer K, Perezpeña-Diazconti, Mario, de León, Fernando Chico Ponce, Robinson, Shenandoah, Zapotocky, Michal, Lassaletta, Alvaro, Huang, Annie, Hawkins, Cynthia E, Tabori, Uri, Bouffet, Eric, Bartels, Ute, Dirks, Peter B, Rutka, James T, Bader, Gary D, Reimand, Jüri, Goldenberg, Anna, Ramaswamy, Vijay, and Taylor, Michael D

Subjects
Genetics, Rare Diseases, Pediatric Cancer, Cancer, Brain Cancer, Pediatric Research Initiative, Pediatric, Human Genome, Brain Disorders, Cluster Analysis, Cohort Studies, DNA Copy Number Variations, DNA Methylation, Gene Expression Profiling, Genomics, Humans, Medulloblastoma, Precision Medicine, copy number, gene expression, integrative clustering, medulloblastoma, methylation, subgroups, Neurosciences, Oncology and Carcinogenesis, Oncology & Carcinogenesis
Abstract

While molecular subgrouping has revolutionized medulloblastoma classification, the extent of heterogeneity within subgroups is unknown. Similarity network fusion (SNF) applied to genome-wide DNA methylation and gene expression data across 763 primary samples identifies very homogeneous clusters of patients, supporting the presence of medulloblastoma subtypes. After integration of somatic copy-number alterations, and clinical features specific to each cluster, we identify 12 different subtypes of medulloblastoma. Integrative analysis using SNF further delineates group 3 from group 4 medulloblastoma, which is not as readily apparent through analyses of individual data types. Two clear subtypes of infants with Sonic Hedgehog medulloblastoma with disparate outcomes and biology are identified. Medulloblastoma subtypes identified through integrative clustering have important implications for stratification of future clinical trials.

Published
2017

12. Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors

Author

Torchia, Jonathon, Golbourn, Brian, Feng, Shengrui, Ho, Ching, Sin-Chan, Patrick, Vasiljevic, Alexandre, Norman, Joseph D, Guilhamon, Paul, Garzia, Livia, Agamez, Natalia R, Lu, Mei, Chan, Tiffany S, Picard, Daniel, de Antonellis, Pasqualino, Khuong-Quang, Dong-Anh, Planello, Aline C, Zeller, Constanze, Barsyte-Lovejoy, Dalia, Lafay-Cousin, Lucie, Letourneau, Louis, Bourgey, Mathieu, Yu, Man, Gendoo, Deena MA, Dzamba, Misko, Barszczyk, Mark, Medina, Tiago, Riemenschneider, Alexandra N, Morrissy, A Sorana, Ra, Young-Shin, Ramaswamy, Vijay, Remke, Marc, Dunham, Christopher P, Yip, Stephen, Ng, Ho-keung, Lu, Jian-Qiang, Mehta, Vivek, Albrecht, Steffen, Pimentel, Jose, Chan, Jennifer A, Somers, Gino R, Faria, Claudia C, Roque, Lucia, Fouladi, Maryam, Hoffman, Lindsey M, Moore, Andrew S, Wang, Yin, Choi, Seung Ah, Hansford, Jordan R, Catchpoole, Daniel, Birks, Diane K, Foreman, Nicholas K, Strother, Doug, Klekner, Almos, Bognár, Laszló, Garami, Miklós, Hauser, Péter, Hortobágyi, Tibor, Wilson, Beverly, Hukin, Juliette, Carret, Anne-Sophie, Van Meter, Timothy E, Hwang, Eugene I, Gajjar, Amar, Chiou, Shih-Hwa, Nakamura, Hideo, Toledano, Helen, Fried, Iris, Fults, Daniel, Wataya, Takafumi, Fryer, Chris, Eisenstat, David D, Scheinemann, Katrin, Fleming, Adam J, Johnston, Donna L, Michaud, Jean, Zelcer, Shayna, Hammond, Robert, Afzal, Samina, Ramsay, David A, Sirachainan, Nongnuch, Hongeng, Suradej, Larbcharoensub, Noppadol, Grundy, Richard G, Lulla, Rishi R, Fangusaro, Jason R, Druker, Harriet, Bartels, Ute, Grant, Ronald, Malkin, David, McGlade, C Jane, Nicolaides, Theodore, Tihan, Tarik, Phillips, Joanna, Majewski, Jacek, Montpetit, Alexandre, Bourque, Guillaume, Bader, Gary D, Reddy, Alyssa T, Gillespie, G Yancey, and Warmuth-Metz, Monika

Subjects
Genetics, Human Genome, Rare Diseases, Orphan Drug, Cancer, 2.1 Biological and endogenous factors, Development of treatments and therapeutic interventions, Aetiology, 5.1 Pharmaceuticals, Cell Line, Tumor, Cell Proliferation, Cell Survival, Central Nervous System Neoplasms, Chromatin, DNA Methylation, Dasatinib, Epigenesis, Genetic, Epigenomics, Humans, Mutation, Protein Kinase Inhibitors, Pyrimidines, Receptor, Platelet-Derived Growth Factor beta, Rhabdoid Tumor, SMARCB1 Protein, Teratoma, ATRT, enhancer, epigenomics, genomics, rhabdoid tumors, subgroup-specific therapeutics, Neurosciences, Oncology and Carcinogenesis, Oncology & Carcinogenesis
Abstract

We recently reported that atypical teratoid rhabdoid tumors (ATRTs) comprise at least two transcriptional subtypes with different clinical outcomes; however, the mechanisms underlying therapeutic heterogeneity remained unclear. In this study, we analyzed 191 primary ATRTs and 10 ATRT cell lines to define the genomic and epigenomic landscape of ATRTs and identify subgroup-specific therapeutic targets. We found ATRTs segregated into three epigenetic subgroups with distinct genomic profiles, SMARCB1 genotypes, and chromatin landscape that correlated with differential cellular responses to a panel of signaling and epigenetic inhibitors. Significantly, we discovered that differential methylation of a PDGFRB-associated enhancer confers specific sensitivity of group 2 ATRT cells to dasatinib and nilotinib, and suggest that these are promising therapies for this highly lethal ATRT subtype.

Published
2016

13. A case of a pilocytic astrocytoma with histological features of anaplasia and unprecedent genetic alterations.

Author

Moritsubo, Mayuko, Furuta, Takuya, Negoto, Tetsuya, Nakamura, Hideo, Uchiyama, Yusuke, Morioka, Motohiro, Oshima, Koichi, and Sugita, Yasuo

Subjects
ASTROCYTOMAS, DNA analysis, GLIOMAS, BRAIN tumors, KI-67 antigen
Abstract

We report a case of pediatric glioma with uncommon imaging, morphological, and genetic features. A one‐year‐old boy incidentally presented with a tumor in the fourth ventricle. The tumor was completely resected surgically and investigated pathologically. The mostly circumscribed tumor had piloid features but primitive and anaplastic histology, such as increasing cellularity and mitosis. The Ki‐67 staining index was 25% at the hotspot. KIAA1549::BRAF fusion and KIAA1549 partial deletions were detected by direct PCR, supported by Sanger sequencing. To the best of our knowledge, this is the first report of a glioma with both deletion of KIAA1549 p.P1771_P1899 and fusion of KIAA1549::BRAF. The tumor could not be classified using DNA methylome analysis. The present tumor fell into the category of pilocytic astrocytoma with histological features of anaplasia (aPA). Further studies are needed to establish pediatric aPA. [ABSTRACT FROM AUTHOR]

Published
2024
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19. A multicenter, randomized, placebo-controlled phase IIb trial of an autologous formalin-fixed tumor vaccine for newly diagnosed glioblastomas

Author

Muragaki, Yoshihiro, primary, Ishikawa, Eiichi, additional, Maruyama, Takashi, additional, Nitta, Masayuki, additional, Saito, Taiichi, additional, Ikuta, Soko, additional, Komori, Takashi, additional, Kawamata, Takakazu, additional, Yamamoto, Tetsuya, additional, Tsuboi, Koji, additional, Matsumura, Akira, additional, Nakamura, Hideo, additional, Kuroda, Junichiro, additional, Abe, Tatsuya, additional, Momii, Yasutomo, additional, Saito, Ryuta, additional, Tominaga, Teiji, additional, Tabei, Yusuke, additional, Suzuki, Ichiro, additional, Arakawa, Yoshiki, additional, Miyamoto, Susumu, additional, Matsutani, Masao, additional, Karasawa, Katsuyuki, additional, Nakazato, Yoichi, additional, Maebayashi, Katsuya, additional, Hashimoto, Koichi, additional, and Ohno, Tadao, additional

Published
2023
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24. Subgroup-specific structural variation across 1,000 medulloblastoma genomes.

Author

Northcott, Paul, Shih, David, Peacock, John, Garzia, Livia, Morrissy, A, Zichner, Thomas, Stütz, Adrian, Korshunov, Andrey, Reimand, Jüri, Schumacher, Steven, Beroukhim, Rameen, Ellison, David, Marshall, Christian, Lionel, Anath, Mack, Stephen, Dubuc, Adrian, Yao, Yuan, Ramaswamy, Vijay, Luu, Betty, Rolider, Adi, Cavalli, Florence, Wang, Xin, Remke, Marc, Wu, Xiaochong, Chiu, Readman, Chu, Andy, Chuah, Eric, Corbett, Richard, Hoad, Gemma, Jackman, Shaun, Li, Yisu, Lo, Allan, Mungall, Karen, Nip, Ka, Qian, Jenny, Raymond, Anthony, Thiessen, Nina, Varhol, Richard, Birol, Inanc, Moore, Richard, Mungall, Andrew, Holt, Robert, Kawauchi, Daisuke, Roussel, Martine, Kool, Marcel, Jones, David, Witt, Hendrick, Fernandez-L, Africa, Kenney, Anna, Wechsler-Reya, Robert, Dirks, Peter, Aviv, Tzvi, Grajkowska, Wieslawa, Perek-Polnik, Marta, Haberler, Christine, Delattre, Olivier, Reynaud, Stéphanie, Doz, François, Pernet-Fattet, Sarah, Cho, Byung-Kyu, Kim, Seung-Ki, Wang, Kyu-Chang, Scheurlen, Wolfram, Eberhart, Charles, Fèvre-Montange, Michelle, Jouvet, Anne, Pollack, Ian, Fan, Xing, Muraszko, Karin, Gillespie, G, Di Rocco, Concezio, Massimi, Luca, Michiels, Erna, Kloosterhof, Nanne, French, Pim, Kros, Johan, Olson, James, Ellenbogen, Richard, Zitterbart, Karel, Kren, Leos, Thompson, Reid, Cooper, Michael, Lach, Boleslaw, McLendon, Roger, Bigner, Darell, Fontebasso, Adam, Albrecht, Steffen, Jabado, Nada, Lindsey, Janet, Bailey, Simon, Van Meir, Erwin, Fouladi, Maryam, Nakamura, Hideo, Cinalli, Giuseppe, Garami, Miklós, Hauser, Peter, Saad, Ali, Iolascon, Achille, Jung, Shin, and Carlotti, Carlos

Subjects
Carrier Proteins, Cerebellar Neoplasms, Child, DNA Copy Number Variations, Gene Duplication, Genes, myc, Genome, Human, Genomic Structural Variation, Genomics, Hedgehog Proteins, Humans, Medulloblastoma, NF-kappa B, Nerve Tissue Proteins, Oncogene Proteins, Fusion, Proteins, RNA, Long Noncoding, Signal Transduction, Transforming Growth Factor beta, Translocation, Genetic
Abstract

Medulloblastoma, the most common malignant paediatric brain tumour, is currently treated with nonspecific cytotoxic therapies including surgery, whole-brain radiation, and aggressive chemotherapy. As medulloblastoma exhibits marked intertumoural heterogeneity, with at least four distinct molecular variants, previous attempts to identify targets for therapy have been underpowered because of small samples sizes. Here we report somatic copy number aberrations (SCNAs) in 1,087 unique medulloblastomas. SCNAs are common in medulloblastoma, and are predominantly subgroup-enriched. The most common region of focal copy number gain is a tandem duplication of SNCAIP, a gene associated with Parkinsons disease, which is exquisitely restricted to Group 4α. Recurrent translocations of PVT1, including PVT1-MYC and PVT1-NDRG1, that arise through chromothripsis are restricted to Group 3. Numerous targetable SCNAs, including recurrent events targeting TGF-β signalling in Group 3, and NF-κB signalling in Group 4, suggest future avenues for rational, targeted therapy.

Published
2012

29. JCOG0911 INTEGRA study: a randomized screening phase II trial of interferonβ plus temozolomide in comparison with temozolomide alone for newly diagnosed glioblastoma

Author

Wakabayashi, Toshihiko, Natsume, Atsushi, Mizusawa, Junki, Katayama, Hiroshi, Fukuda, Haruhiko, Sumi, Minako, Nishikawa, Ryo, Narita, Yoshitaka, Muragaki, Yoshihiro, Maruyama, Takashi, Ito, Tamio, Beppu, Takaaki, Nakamura, Hideo, Kayama, Takamasa, Sato, Shinya, Nagane, Motoo, Mishima, Kazuhiko, Nakasu, Yoko, Kurisu, Kaoru, Yamasaki, Fumiyuki, Sugiyama, Kazuhiko, Onishi, Takanori, Iwadate, Yasuo, Terasaki, Mizuhiko, Kobayashi, Hiroyuki, Matsumura, Akira, Ishikawa, Eiichi, Sasaki, Hikaru, Mukasa, Akitake, Matsuo, Takayuki, Hirano, Hirofumi, Kumabe, Toshihiro, Shinoura, Nobusada, Hashimoto, Naoya, Aoki, Tomokazu, Asai, Akio, Abe, Tatsuya, Yoshino, Atsuo, Arakawa, Yoshiki, Asano, Kenichiro, Yoshimoto, Koji, Shibui, Soichiro, and Members of Japan Clinical Oncology Group Brain Tumor Study Group (JCOG-BTSG)

Published
2018
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33. Data from NKX2.2 Suppresses Self-Renewal of Glioma-Initiating Cells

Author

Muraguchi, Teruyuki, primary, Tanaka, Shingo, primary, Yamada, Daisuke, primary, Tamase, Akira, primary, Nakada, Mitsutoshi, primary, Nakamura, Hideo, primary, Hoshii, Takayuki, primary, Ooshio, Takako, primary, Tadokoro, Yuko, primary, Naka, Kazuhito, primary, Ino, Yasushi, primary, Todo, Tomoki, primary, Kuratsu, Jun-ichi, primary, Saya, Hideyuki, primary, Hamada, Jun-ichiro, primary, and Hirao, Atsushi, primary

Published
2023
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39. Supplementary Figures 1-5, Table 1 from NKX2.2 Suppresses Self-Renewal of Glioma-Initiating Cells

Author

Muraguchi, Teruyuki, primary, Tanaka, Shingo, primary, Yamada, Daisuke, primary, Tamase, Akira, primary, Nakada, Mitsutoshi, primary, Nakamura, Hideo, primary, Hoshii, Takayuki, primary, Ooshio, Takako, primary, Tadokoro, Yuko, primary, Naka, Kazuhito, primary, Ino, Yasushi, primary, Todo, Tomoki, primary, Kuratsu, Jun-ichi, primary, Saya, Hideyuki, primary, Hamada, Jun-ichiro, primary, and Hirao, Atsushi, primary

Published
2023
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42. Supplementary Figures SF1-SF8 from Mathematical Modeling and Mutational Analysis Reveal Optimal Therapy to Prevent Malignant Transformation in Grade II IDH-Mutant Gliomas

Author

Aoki, Kosuke, primary, Suzuki, Hiromichi, primary, Yamamoto, Takashi, primary, Yamamoto, Kimiyo N., primary, Maeda, Sachi, primary, Okuno, Yusuke, primary, Ranjit, Melissa, primary, Motomura, Kazuya, primary, Ohka, Fumiharu, primary, Tanahashi, Kuniaki, primary, Hirano, Masaki, primary, Nishikawa, Tomohide, primary, Shimizu, Hiroyuki, primary, Kitano, Yotaro, primary, Yamaguchi, Junya, primary, Yamazaki, Shintaro, primary, Nakamura, Hideo, primary, Takahashi, Masamichi, primary, Narita, Yoshitaka, primary, Nakada, Mitsutoshi, primary, Deguchi, Shoichi, primary, Mizoguchi, Masahiro, primary, Momii, Yasutomo, primary, Muragaki, Yoshihiro, primary, Abe, Tatsuya, primary, Akimoto, Jiro, primary, Wakabayashi, Toshihiko, primary, Saito, Ryuta, primary, Ogawa, Seishi, primary, Haeno, Hiroshi, primary, and Natsume, Atsushi, primary

Published
2023
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43. Supplementary Table from Mathematical Modeling and Mutational Analysis Reveal Optimal Therapy to Prevent Malignant Transformation in Grade II IDH-Mutant Gliomas

Author

Aoki, Kosuke, primary, Suzuki, Hiromichi, primary, Yamamoto, Takashi, primary, Yamamoto, Kimiyo N., primary, Maeda, Sachi, primary, Okuno, Yusuke, primary, Ranjit, Melissa, primary, Motomura, Kazuya, primary, Ohka, Fumiharu, primary, Tanahashi, Kuniaki, primary, Hirano, Masaki, primary, Nishikawa, Tomohide, primary, Shimizu, Hiroyuki, primary, Kitano, Yotaro, primary, Yamaguchi, Junya, primary, Yamazaki, Shintaro, primary, Nakamura, Hideo, primary, Takahashi, Masamichi, primary, Narita, Yoshitaka, primary, Nakada, Mitsutoshi, primary, Deguchi, Shoichi, primary, Mizoguchi, Masahiro, primary, Momii, Yasutomo, primary, Muragaki, Yoshihiro, primary, Abe, Tatsuya, primary, Akimoto, Jiro, primary, Wakabayashi, Toshihiko, primary, Saito, Ryuta, primary, Ogawa, Seishi, primary, Haeno, Hiroshi, primary, and Natsume, Atsushi, primary

Published
2023
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44. Supplementary Material and Methods from Mathematical Modeling and Mutational Analysis Reveal Optimal Therapy to Prevent Malignant Transformation in Grade II IDH-Mutant Gliomas

Author

Aoki, Kosuke, primary, Suzuki, Hiromichi, primary, Yamamoto, Takashi, primary, Yamamoto, Kimiyo N., primary, Maeda, Sachi, primary, Okuno, Yusuke, primary, Ranjit, Melissa, primary, Motomura, Kazuya, primary, Ohka, Fumiharu, primary, Tanahashi, Kuniaki, primary, Hirano, Masaki, primary, Nishikawa, Tomohide, primary, Shimizu, Hiroyuki, primary, Kitano, Yotaro, primary, Yamaguchi, Junya, primary, Yamazaki, Shintaro, primary, Nakamura, Hideo, primary, Takahashi, Masamichi, primary, Narita, Yoshitaka, primary, Nakada, Mitsutoshi, primary, Deguchi, Shoichi, primary, Mizoguchi, Masahiro, primary, Momii, Yasutomo, primary, Muragaki, Yoshihiro, primary, Abe, Tatsuya, primary, Akimoto, Jiro, primary, Wakabayashi, Toshihiko, primary, Saito, Ryuta, primary, Ogawa, Seishi, primary, Haeno, Hiroshi, primary, and Natsume, Atsushi, primary

Published
2023
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45. Data from Mathematical Modeling and Mutational Analysis Reveal Optimal Therapy to Prevent Malignant Transformation in Grade II IDH-Mutant Gliomas

Author

Aoki, Kosuke, primary, Suzuki, Hiromichi, primary, Yamamoto, Takashi, primary, Yamamoto, Kimiyo N., primary, Maeda, Sachi, primary, Okuno, Yusuke, primary, Ranjit, Melissa, primary, Motomura, Kazuya, primary, Ohka, Fumiharu, primary, Tanahashi, Kuniaki, primary, Hirano, Masaki, primary, Nishikawa, Tomohide, primary, Shimizu, Hiroyuki, primary, Kitano, Yotaro, primary, Yamaguchi, Junya, primary, Yamazaki, Shintaro, primary, Nakamura, Hideo, primary, Takahashi, Masamichi, primary, Narita, Yoshitaka, primary, Nakada, Mitsutoshi, primary, Deguchi, Shoichi, primary, Mizoguchi, Masahiro, primary, Momii, Yasutomo, primary, Muragaki, Yoshihiro, primary, Abe, Tatsuya, primary, Akimoto, Jiro, primary, Wakabayashi, Toshihiko, primary, Saito, Ryuta, primary, Ogawa, Seishi, primary, Haeno, Hiroshi, primary, and Natsume, Atsushi, primary

Published
2023
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46. Clinicopathologic analysis of pineal parenchymal tumors of intermediate differentiation: a multi-institutional cohort study by the Kyushu Neuro-Oncology Study Group

Author

Yamashita, Shinji, primary, Takeshima, Hideo, additional, Hata, Nobuhiro, additional, Uchida, Hiroyuki, additional, Shinojima, Naoki, additional, Yokogami, Kiyotaka, additional, Nakano, Yoshiteru, additional, Sakata, Kiyohiko, additional, Fudaba, Hirotaka, additional, Enomoto, Toshiyuki, additional, Nakahara, Yukiko, additional, Ujifuku, Kenta, additional, Sugawara, Kenichi, additional, Iwaki, Tooru, additional, Sangatsuda, Yuhei, additional, Yoshimoto, Koji, additional, Hanaya, Ryousuke, additional, Mukasa, Akitake, additional, Suzuki, Kohei, additional, Yamamoto, Junkoh, additional, Negoto, Tetsuya, additional, Nakamura, Hideo, additional, Momii, Yasutomo, additional, Fujiki, Minoru, additional, Abe, Hiroshi, additional, Masuoka, Jyun, additional, Abe, Tatsuya, additional, Matsuo, Takayuki, additional, and Ishiuchi, Shogo, additional

Published
2023
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47. Successful Treatment of Pure Aqueductal Pilomyxoid Astrocytoma and Arrested Hydrocephalus With Endoscopic Tumor Resection Followed by Chemotherapy: A Case Report and Technical Considerations

Author

Sakata, Kiyohiko, primary, Hashimoto, Aya, additional, Kotaki, Yoshikuni, additional, Yoshitake, Hidenobu, additional, Shimokawa, Shoko, additional, Komaki, Satoru, additional, Nakamura, Hideo, additional, Furuta, Takuya, additional, and Morioka, Motohiro, additional

Published
2023
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