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34 results on '"Nechaeva, Natalia"'

1. SERS for Bacteria, Viruses, and Protein Biosensing

Author

Kurochkin, Ilya N., Eremenko, Arkadiy V., Evtushenko, Evgeniy G., Nechaeva, Natalia L., Durmanov, Nikolay N., Guliev, Rustam R., Ryzhikov, Ilya A., Boginskaya, Irina A., Sarychev, Andrey K., Ivanov, A. V., Lagarkov, Andrey N., Rai, Mahendra, editor, Reshetilov, Anatoly, editor, Plekhanova, Yulia, editor, and Ingle, Avinash P, editor

Published
2021
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6. In Situ SERS Sensing by a Laser-Induced Aggregation of Silver Nanoparticles Templated on a Thermoresponsive Polymer

Author

Sigolaeva, Larisa V., primary, Nechaeva, Natalia L., additional, Ignatov, Anton I., additional, Filatova, Lyubov Y., additional, Sharifullin, Timur Z., additional, Eichhorn, Jonas, additional, Schacher, Felix H., additional, Pergushov, Dmitry V., additional, Merzlikin, Alexander M., additional, and Kurochkin, Ilya N., additional

Published
2022
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7. SERS for Bacteria, Viruses, and Protein Biosensing

Author

Kurochkin, Ilya N., Eremenko, Arkadiy V., Evtushenko, Evgeniy G., Nechaeva, Natalia L., Durmanov, Nikolay N., Guliev, Rustam R., Ryzhikov, Ilya A., Boginskaya, Irina A., Sarychev, Andrey K., Ivanov, A. V., and Lagarkov, Andrey N.

Subjects
SERS, enzymes, viruses, biosensing, bacteria, Article, proteins
Abstract

In this chapter, various techniques are reviewed with focus on the identification of complex biological agents such as bacteria, viruses, proteins, and enzymes using SERS-active silver substrates. Biological targets have multiple peculiarities that add to the challenges of the SERS biosensing. In regards to the direct non-labeled sensing of bacteria, it was discovered that all bands in the registered SER spectra were generated by metabolites released from bacterial cells. It undermined the prior notion of non-labeled detection and identification of bacteria based on the presumed spectra of cellular walls. However, it also provides new opportunities for the SERS analysis of bacteria. The SERS measurements of viruses can be performed with SERS-active surfaces or colloidal solutions of silver nanoparticles. However, the use of surfaces requires extensive sample preparation and often lacks sensitivity, while colloidal SERS substrates have another problem—most types of silver nanoparticles are negatively charged and have a poor interaction with likewise predominantly negatively charged virions. Thus, a challenge is posed to develop SERS-ready positively charged silver nanoparticles or use other methods to enforce the non-specific binding of viruses to the silver surfaces. Meanwhile, SER spectra of proteins are nearly impossible to acquire at adequate sensitivity. Thus, non-direct measurements are the only way. SERS provides the most benefits when working with relatively small molecules, so small molecules serving as Raman probes can be used as an intermediary to produce SER spectra. For enzymes like butyrylcholinesterase, it means measuring SER spectra of substrates and products of the relevant reaction, while for other proteins, specialized techniques must be developed. It can be concluded that biological targets require a case-by-case approach. Prior experiences with direct SERS measurements of highly Raman-active molecules like R6G and others often used in fundamental studies might not be relevant in bioanalytics.

Published
2020

8. Human Angiotensin I-Converting Enzyme Produced by Different Cells: Classification of the SERS Spectra with Linear Discriminant Analysis

Author

Boginskaya, Irina, primary, Safiullin, Robert, additional, Tikhomirova, Victoria, additional, Kryukova, Olga, additional, Nechaeva, Natalia, additional, Bulaeva, Naida, additional, Golukhova, Elena, additional, Ryzhikov, Ilya, additional, Kost, Olga, additional, Afanasev, Konstantin, additional, and Kurochkin, Ilya, additional

Published
2022
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10. Развитие познавательной активности ребенка дошкольного возраста

Author

Chebotariova Iuliia Evgen'evna, Katelnikova Anna Sergeevna, and Nechaeva Natalia Anatolevna

Subjects
развитие, ребенок, познавательная активность, любознательность
Abstract

В статье представлен анализ понятия «познавательная активность», процесс развития познавательной активности в дошкольном возрасте, а также факторы, влияющие на формирование познавательной активности.

Published
2021

11. Formirovanie samootsenki rebenka doshkol'nogo vozrasta

Author

Chebotariova Iuliia Evgen'evna, Koreeva Tatiana Viacheslavovna, and Nechaeva Natalia Anatolevna

Subjects
самооценка, развитие, дети, педагогика
Abstract

В статье представлен анализ понятия «самооценка», процесс формирования самооценки в дошкольном возрасте, факторы, влияющие на становление самооценки.

Published
2021

12. Formirovanie lichnosti v doshkol'nom vozraste

Author

Chebotariova Iuliia Evgen'evna and Nechaeva Natalia Anatolevna

Subjects
воспитание, дошкольники, педагогика, личность
Abstract

В статье представлен анализ понятия «личность», процесс становления личности в дошкольном возрасте, факторы развития личности.

Published
2021

14. SERS Sensor for Human Glycated Albumin Direct Assay Based on Machine Learning Methods.

Author

Slipchenko, Ekaterina A., Boginskaya, Irina A., Safiullin, Robert R., Ryzhikov, Ilya A., Sedova, Marina V., Afanasev, Konstantin N., Nechaeva, Natalia L., Kurochkin, Ilya N., Merzlikin, Alexander M., and Lagarkov, Andrey N.

Subjects
MACHINE learning, FISHER discriminant analysis, DATA augmentation, SERUM albumin, SERS spectroscopy, RANDOM forest algorithms
Abstract

In this study, a non-labeled sensor system for direct determining human glycated albumin levels for medical application is proposed. Using machine learning methods applied to surface-enhanced Raman scattering (SERS) spectra of human glycated albumin and serum human albumin enabled the avoidance of complex sample preparation. By implementing linear discriminant analysis and regularized linear regression, classification and regression problems were solved based on the spectra obtained as a result of the experiment. The results show that, coupled with data augmentation and a special cross-validation procedure, the methods we employed yield better results in the corresponding tasks in comparison with popular random forest methods and the support vector method. The results show that SERS, in combination with machine learning methods, can be a powerful and effective tool for the simple and direct assay of protein mixtures. [ABSTRACT FROM AUTHOR]

Published
2022
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15. Взаимодействие педагогов ДОУ в работе с детьми с ОВЗ

Author

Panina Svetlana Iurevna, Gudina Viktoriia Iurevna, and Nechaeva Natalia Iurevna

Subjects
педагогический процесс, дети с ОВЗ, образовательное пространство
Abstract

В статье анализируется проблема взаимодействия педагогов ДОУ при работе с детьми с ОВЗ. Авторами отмечено возрастание количества детей с ОВЗ, что актуализирует обращение к заявленной проблематике.

Published
2020

16. Формирование личности в дошкольном возрасте

Author

Чеботарёва Юлия Евгеньевна, МБДОУ «Д/С №46 «Колокольчик», Chebotariova Iuliia Evgen'evna, MSBEI K/g of a combined type №46 "Kolokolchik", Нечаева Наталья Анатольевна, Nechaeva Natalia Anatolevna, Чеботарёва Юлия Евгеньевна, МБДОУ «Д/С №46 «Колокольчик», Chebotariova Iuliia Evgen'evna, MSBEI K/g of a combined type №46 "Kolokolchik", Нечаева Наталья Анатольевна, and Nechaeva Natalia Anatolevna

Abstract

В статье представлен анализ понятия «личность», процесс становления личности в дошкольном возрасте, факторы развития личности.

Published
2021

17. Формирование самооценки ребенка дошкольного возраста

Author

Чеботарёва Юлия Евгеньевна, МБДОУ «Д/С №46 «Колокольчик», Chebotariova Iuliia Evgen'evna, MSBEI K/g of a combined type №46 "Kolokolchik", Кореева Татьяна Вячеславовна, Koreeva Tatiana Viacheslavovna, Нечаева Наталья Анатольевна, Nechaeva Natalia Anatolevna, Чеботарёва Юлия Евгеньевна, МБДОУ «Д/С №46 «Колокольчик», Chebotariova Iuliia Evgen'evna, MSBEI K/g of a combined type №46 "Kolokolchik", Кореева Татьяна Вячеславовна, Koreeva Tatiana Viacheslavovna, Нечаева Наталья Анатольевна, and Nechaeva Natalia Anatolevna

Abstract

В статье представлен анализ понятия «самооценка», процесс формирования самооценки в дошкольном возрасте, факторы, влияющие на становление самооценки.

Published
2021

18. Развитие познавательной активности ребенка дошкольного возраста

Author

Чеботарёва Юлия Евгеньевна, МБДОУ «Д/С №46 «Колокольчик», Chebotariova Iuliia Evgen'evna, MSBEI K/g of a combined type №46 "Kolokolchik", Кательникова Анна Сергеевна, Katelnikova Anna Sergeevna, Нечаева Наталья Анатольевна, Nechaeva Natalia Anatolevna, Чеботарёва Юлия Евгеньевна, МБДОУ «Д/С №46 «Колокольчик», Chebotariova Iuliia Evgen'evna, MSBEI K/g of a combined type №46 "Kolokolchik", Кательникова Анна Сергеевна, Katelnikova Anna Sergeevna, Нечаева Наталья Анатольевна, and Nechaeva Natalia Anatolevna

Abstract

В статье представлен анализ понятия «познавательная активность», процесс развития познавательной активности в дошкольном возрасте, а также факторы, влияющие на формирование познавательной активности.

Published
2021

20. Human angiotensin I‐converting enzyme study by surface‐enhanced Raman spectroscopy

Author

Boginskaya, Irina, primary, Nechaeva, Natalia, additional, Tikhomirova, Victoria, additional, Kryukova, Olga, additional, Evdokimov, Valery, additional, Bulaeva, Naida, additional, Golukhova, Elena, additional, Ryzhikov, Ilya, additional, Kost, Olga, additional, Afanasev, Konstantin, additional, Vereshchagin, Konstantin, additional, and Kurochkin, Ilya, additional

Published
2021
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22. Взаимодействие педагогов ДОУ в работе с детьми с ОВЗ

Author

Панина Светлана Юрьевна, МБДОУ «Д/С №46 «Колокольчик», Panina Svetlana Iurevna, MSBEI K/g of a combined type №46 "Kolokolchik", Гудина Виктория Юрьевна, Gudina Viktoriia Iurevna, Нечаева Наталья Анатольевна, МБДОУ Д/С №46 «Колокольчик», Nechaeva Natalia Iurevna, MBDOU D/S KV 46 "Kolokol'chik" g. Belgoroda, Панина Светлана Юрьевна, МБДОУ «Д/С №46 «Колокольчик», Panina Svetlana Iurevna, MSBEI K/g of a combined type №46 "Kolokolchik", Гудина Виктория Юрьевна, Gudina Viktoriia Iurevna, Нечаева Наталья Анатольевна, МБДОУ Д/С №46 «Колокольчик», Nechaeva Natalia Iurevna, and MBDOU D/S KV 46 "Kolokol'chik" g. Belgoroda

Abstract

В статье анализируется проблема взаимодействия педагогов ДОУ при работе с детьми с ОВЗ. Авторами отмечено возрастание количества детей с ОВЗ, что актуализирует обращение к заявленной проблематике.

Published
2020

28. Laser intensity limits in surface‐enhanced linear and nonlinear Raman micro‐spectroscopy of organic molecule/Au‐nanoparticle conjugates

Author

Fabelinsky, Victor I., primary, Kozlov, Dimitrii N., additional, Polivanov, Yury N., additional, Smirnov, Valery V., additional, Bokova‐Sirosh, Sofia N., additional, Obraztsova, Elena D., additional, Arzumanyan, Grigory M., additional, Mamatkulov, Kahramon Z., additional, Afanasiev, Konstantin N., additional, Boginskaya, Irina A., additional, Budashov, Igor A., additional, and Nechaeva, Natalia L., additional

Published
2019
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30. Развитие познавательной активности у младших школьников с ЗПР

Author

Нечаева Наталья Семёновна, ФГБОУ ВО «Мурманский арктический государственный университет», Nechaeva Natalia Semionovna, FSBEI of HE "Murmansk Arctic State University", Нечаева Наталья Семёновна, ФГБОУ ВО «Мурманский арктический государственный университет», Nechaeva Natalia Semionovna, and FSBEI of HE "Murmansk Arctic State University"

Abstract

Статья посвящена анализу понятия «познавательная активность», проблеме развития познавательной активности у младших школьников с задержкой психического развития.

Published
2018

33. Surface-enhanced micro-CARS mapping of a nanostructured cerium dioxide/aluminum film surface with gold nanoparticle-bound organic molecules

Author

Fabelinsky, Viktor I., primary, Kozlov, Dimitrii N., additional, Orlov, Sergey N., additional, Polivanov, Yury N., additional, Shcherbakov, Ivan A., additional, Smirnov, Valery V., additional, Vereschagin, Konstantin A., additional, Arzumanyan, Grigory M., additional, Mamatkulov, Kahramon Z., additional, Afanasiev, Konstantin N., additional, Lagarkov, Andrey N., additional, Ryzhikov, Ilya A., additional, Sarychev, Andrey K., additional, Budashov, Igor A., additional, Nechaeva, Natalia L., additional, and Kurochkin, Ilya N., additional

Published
2018
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