Search

Your search keyword '"Nelson, Christopher"' showing total 3,508 results
Start Over Author "Nelson, Christopher"
3,508 results on '"Nelson, Christopher"'

3. Theology

Author

Nelson, Christopher

Published
2023

7. Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits.

Author

Keaton, Jacob, Kamali, Zoha, Xie, Tian, Vaez, Ahmad, Williams, Ariel, Goleva, Slavina, Ani, Alireza, Evangelou, Evangelos, Hellwege, Jacklyn, Yengo, Loic, Young, William, Traylor, Matthew, Giri, Ayush, Zheng, Zhili, Zeng, Jian, Chasman, Daniel, Morris, Andrew, Caulfield, Mark, Hwang, Shih-Jen, Kooner, Jaspal, Conen, David, Attia, John, Morrison, Alanna, Loos, Ruth, Kristiansson, Kati, Schmidt, Reinhold, Hicks, Andrew, Pramstaller, Peter, Nelson, Christopher, Samani, Nilesh, Risch, Lorenz, Gyllensten, Ulf, Melander, Olle, Riese, Harriette, Wilson, James, Campbell, Harry, Rich, Stephen, Psaty, Bruce, Lu, Yingchang, Guo, Xiuqing, Rice, Kenneth, Vollenweider, Peter, Sundström, Johan, Langenberg, Claudia, Tobin, Martin, Giedraitis, Vilmantas, Luan, Jianan, Tuomilehto, Jaakko, Kutalik, Zoltan, Ripatti, Samuli, Salomaa, Veikko, Girotto, Giorgia, Trompet, Stella, Jukema, J, van der Harst, Pim, Ridker, Paul, Giulianini, Franco, Vitart, Veronique, Goel, Anuj, Watkins, Hugh, Harris, Sarah, Deary, Ian, van der Most, Peter, Oldehinkel, Albertine, Keavney, Bernard, Hayward, Caroline, Campbell, Archie, Boehnke, Michael, Scott, Laura, Boutin, Thibaud, Mamasoula, Chrysovalanto, Järvelin, Marjo-Riitta, Peters, Annette, Gieger, Christian, Lakatta, Edward, Cucca, Francesco, Hui, Jennie, Knekt, Paul, Enroth, Stefan, De Borst, Martin, Polašek, Ozren, Concas, Maria, Catamo, Eulalia, Cocca, Massimiliano, Li-Gao, Ruifang, Hofer, Edith, Schmidt, Helena, Spedicati, Beatrice, Waldenberger, Melanie, Strachan, David, Laan, Maris, Teumer, Alexander, Dörr, Marcus, Gudnason, Vilmundur, Cook, James, Ruggiero, Daniela, Kolcic, Ivana, Boerwinkle, Eric, Traglia, Michela, and Lehtimäki, Terho

Subjects
Female, Humans, Male, Blood Pressure, Genetic Predisposition to Disease, Genetic Risk Score, Genome-Wide Association Study, Hypertension, Multifactorial Inheritance, Polymorphism, Single Nucleotide, Risk Factors
Abstract

Hypertension affects more than one billion people worldwide. Here we identify 113 novel loci, reporting a total of 2,103 independent genetic signals (P

Published
2024

8. Investigating the Impact of Gender Composition on Team Performance: A Cross-Cultural Study of Student Teams

Author

Randazzo-Davis, Maria and Nelson, Christopher

Abstract

This study investigated if the gender composition of teams impacts performance by examining the relationship between student-level variables of cultural intelligence and global knowledge and team-level variables of team performance. Data were collected from 1,922 students across 40 countries participating in 446 teams. Results of independent samples t-tests, as well as multiple regression analyses at the student and team levels, showed that gender and international status were related to global knowledge and cultural intelligence, whereas gender, global knowledge, and cultural intelligence were all significantly related to team performance. The coefficient of variation was found to be low, suggesting that other variables might be related to team performance, cultural intelligence, and global knowledge. Implications and limitations are discussed.

Published
2023

9. Genetic architecture of telomere length in 462,666 UK Biobank whole-genome sequences

Author

Burren, Oliver S., Dhindsa, Ryan S., Deevi, Sri V. V., Wen, Sean, Nag, Abhishek, Mitchell, Jonathan, Hu, Fengyuan, Loesch, Douglas P., Smith, Katherine R., Razdan, Neetu, Olsson, Henric, Platt, Adam, Vitsios, Dimitrios, Wu, Qiang, Codd, Veryan, Nelson, Christopher P., Samani, Nilesh J., March, Ruth E., Wasilewski, Sebastian, Carss, Keren, Fabre, Margarete, Wang, Quanli, Pangalos, Menelas N., and Petrovski, Slavé

Published
2024
Full Text
View/download PDF

13. Is atrial fibrillation in HFpEF a distinct phenotype? Insights from multiparametric MRI and circulating biomarkers

Author

Dattani, Abhishek, Brady, Emer M., Kanagala, Prathap, Stoma, Svetlana, Parke, Kelly S., Marsh, Anna-Marie, Singh, Anvesha, Arnold, Jayanth R., Moss, Alastair J., Zhao, Lei, Cvijic, Mary Ellen, Fronheiser, Matthew, Du, Shuyan, Costet, Philippe, Schafer, Peter, Carayannopoulos, Leon, Chang, Ching-Pin, Gordon, David, Ramirez-Valle, Francisco, Jerosch-Herold, Michael, Nelson, Christopher P., Squire, Iain B., Ng, Leong L., Gulsin, Gaurav S., and McCann, Gerry P.

Published
2024
Full Text
View/download PDF

14. OXR1 maintains the retromer to delay brain aging under dietary restriction

Author

Wilson, Kenneth A., Bar, Sudipta, Dammer, Eric B., Carrera, Enrique M., Hodge, Brian A., Hilsabeck, Tyler A. U., Bons, Joanna, Brownridge, III, George W., Beck, Jennifer N., Rose, Jacob, Granath-Panelo, Melia, Nelson, Christopher S., Qi, Grace, Gerencser, Akos A., Lan, Jianfeng, Afenjar, Alexandra, Chawla, Geetanjali, Brem, Rachel B., Campeau, Philippe M., Bellen, Hugo J., Schilling, Birgit, Seyfried, Nicholas T., Ellerby, Lisa M., and Kapahi, Pankaj

Published
2024
Full Text
View/download PDF

15. contents

Author

Nelson, Christopher T., Chow, Rey, Harootunian, Harry, and Miyoshi, Masao

Published
2008

16. 4 in a samurai village

Author

Nelson, Christopher T., Chow, Rey, Harootunian, Harry, and Miyoshi, Masao

Published
2008

17. notes

Author

Nelson, Christopher T., Chow, Rey, Harootunian, Harry, and Miyoshi, Masao

Published
2008

18. bibliography

Author

Nelson, Christopher T., Chow, Rey, Harootunian, Harry, and Miyoshi, Masao

Published
2008

19. index

Author

Nelson, Christopher T., Chow, Rey, Harootunian, Harry, and Miyoshi, Masao

Published
2008

20. title page, copyright

Author

Nelson, Christopher T., Chow, Rey, Harootunian, Harry, and Miyoshi, Masao

Published
2008

26. acknowledgments

Author

Nelson, Christopher T., Chow, Rey, Harootunian, Harry, and Miyoshi, Masao

Published
2008

31. Hedging irrigated maize crop yields using temperature derivatives in Malawi

Author

Prince Blackson Dennis Chirwa and Nelson Christopher Dzupire

Subjects
Derivatives, Growing degree day, Temperature, Barrier option pricing, Science (General), Q1-390, Social sciences (General), H1-99
Abstract

Agriculture production yield varies with weather changes. This causes farmers incur loses. For instance, extreme temperature leads to low maize yield. This study describes incomplete temperature weather derivatives in agriculture markets and applies risk management hedging techniques. It focuses on hedging crop yield against extreme temperatures during irrigation, farming which is done without greenhouse. This study's primary goal is to hedge irrigated maize crop yields using temperature derivatives. This is achieved firstly by modelling a daily average temperature stochastical model. Then, deriving statistical properties of the model based on 1990–2020 Kasungu District Temperature historical data. Lastly, pricing temperature derivatives to hedge maize crop yield. This study uses 1990–2020 Kasungu District Temperature historical data. Then a stochastically Ornstein-Uhlenbeck process with the time-varying speed of reversion, seasonal mean, and local volatility that depends on the local average temperature was proposed. Based on the average temperature model, down and output barrier option pricing models for average temperature and growing degree day (GDD) are applied. The study results shows that when the GDD is above the barrier level the barrier option does not knock out. Hence gives the holder the right to buy the underlying asset since it does not reach or fall below a predefined level over the option's lifetime. If the GDD does not exceed the barrier level, then the farmer will not have to pay the premium because the option is invalid. On the same note, the farmer will have to exercise his right by paying the premium of calculated premium when the GDD exceeds the barrier level. In return for this, the farmer gets paid off which happens to be the difference between GDD and barrier multiplied $1. In line with Malawi's 2063 Millennium Development Goals (MDGs), this study acts as an eye opener for the government to put a policy on whether derivatives should be practised in our country hence, increase cash holding by improving the situation of the farmer and country.

Published
2024
Full Text
View/download PDF

33. Genome-wide association meta-analysis of spontaneous coronary artery dissection identifies risk variants and genes related to artery integrity and tissue-mediated coagulation.

Author

Adlam, David, Berrandou, Takiy-Eddine, Georges, Adrien, Nelson, Christopher, Giannoulatou, Eleni, Henry, Joséphine, Ma, Lijiang, Blencowe, Montgomery, Turley, Tamiel, Yang, Min-Lee, Chopade, Sandesh, Finan, Chris, Braund, Peter, Sadeg-Sayoud, Ines, Iismaa, Siiri, Kosel, Matthew, Zhou, Xiang, Hamby, Stephen, Cheng, Jenny, Liu, Lu, Tarr, Ingrid, Muller, David, dEscamard, Valentina, King, Annette, Brunham, Liam, Baranowska-Clarke, Ania, Debette, Stéphanie, Amouyel, Philippe, Olin, Jeffrey, Patil, Snehal, Hesselson, Stephanie, Junday, Keerat, Kanoni, Stavroula, Aragam, Krishna, Butterworth, Adam, Tweet, Marysia, Gulati, Rajiv, Combaret, Nicolas, Kadian-Dodov, Daniella, Kalman, Jonathan, Fatkin, Diane, Hingorani, Aroon, Saw, Jacqueline, Webb, Tom, Hayes, Sharonne, Yang, Xia, Ganesh, Santhi, Olson, Timothy, Kovacic, Jason, Graham, Robert, Samani, Nilesh, and Bouatia-Naji, Nabila

Subjects
Humans, Female, Genome-Wide Association Study, Vascular Diseases, Coronary Artery Disease, Myocardial Infarction
Abstract

Spontaneous coronary artery dissection (SCAD) is an understudied cause of myocardial infarction primarily affecting women. It is not known to what extent SCAD is genetically distinct from other cardiovascular diseases, including atherosclerotic coronary artery disease (CAD). Here we present a genome-wide association meta-analysis (1,917 cases and 9,292 controls) identifying 16 risk loci for SCAD. Integrative functional annotations prioritized genes that are likely to be regulated in vascular smooth muscle cells and artery fibroblasts and implicated in extracellular matrix biology. One locus containing the tissue factor gene F3, which is involved in blood coagulation cascade initiation, appears to be specific for SCAD risk. Several associated variants have diametrically opposite associations with CAD, suggesting that shared biological processes contribute to both diseases, but through different mechanisms. We also infer a causal role for high blood pressure in SCAD. Our findings provide novel pathophysiological insights involving arterial integrity and tissue-mediated coagulation in SCAD and set the stage for future specific therapeutics and preventions.

Published
2023

34. Polymeric jets throw light on the origin and nature of the forest of solar spicules

Author

Dey, Sahel, Chatterjee, Piyali, N., Murthy O. V. S., Korsos, Marianna B., Liu, Jiajia, Nelson, Christopher J., and Erdelyi, Robertus

Subjects
Astrophysics - Solar and Stellar Astrophysics, Physics - Fluid Dynamics
Abstract

Spicules are plasma jets, observed in the dynamic interface region between the visible solar surface and the hot corona. At any given time, it is estimated that about 3 million spicules are present on the Sun. We find an intriguing parallel between the simulated spicular forest in a solar-like atmosphere and the numerous jets of polymeric fluids when both are subjected to harmonic forcing. In a radiative magnetohydrodynamic numerical simulation with sub-surface convection, solar global surface oscillations are excited similarly to those harmonic vibrations. The jets thus produced match remarkably well with the forests of spicules detected in observations of the Sun. Taken together, the numerical simulations of the Sun and the laboratory fluid dynamics experiments provide insights into the mechanism underlying the ubiquity of jets: the nonlinear focusing of quasi-periodic waves in anisotropic media of magnetized plasma as well as polymeric fluids under gravity is sufficient to generate a forest of spicules on the Sun., Comment: Published in Nature Physics. Video files are available at https://rdcu.be/cZdld

Published
2022
Full Text
View/download PDF

35. Deconstructing heterogeneity of replicative senescence in human mesenchymal stem cells at single cell resolution

Author

Taherian Fard, Atefeh, Leeson, Hannah C., Aguado, Julio, Pietrogrande, Giovanni, Power, Dominique, Gómez-Inclán, Cecilia, Zheng, Huiwen, Nelson, Christopher B., Soheilmoghaddam, Farhad, Glass, Nick, Dharmaratne, Malindrie, Watson, Ebony R., Lu, Jennifer, Martin, Sally, Pickett, Hilda A., Cooper-White, Justin, Wolvetang, Ernst J., and Mar, Jessica C.

Published
2024
Full Text
View/download PDF

38. Surface-Driven Evolution of the Anomalous Hall Effect in Magnetic Topological Insulator MnBi2Te4 Thin Films

Author

Mazza, Alessandro R., Lapano, Jason, Meyer III, Harry M., Nelson, Christopher T., Smith, Tyler, Pai, Yun-Yi, Noordhoek, Kyle, Lawrie, Benjamin J., Charlton, Timothy R., Moore, Robert G., Ward, T. Zac, Du, Mao-Hua, Eres, Gyula, and Brahlek, Matthew

Subjects
Condensed Matter - Materials Science
Abstract

Understanding the effects of interfacial modification to the functional properties of magnetic topological insulator thin films is crucial for developing novel technological applications from spintronics to quantum computing. Here, we report that a large electronic and magnetic response is induced in the intrinsic magnetic topological insulator MnBi2Te4 by controlling the propagation of surface oxidation. We show that the formation of the surface oxide layer is confined to the top 1-2 unit cells but drives large changes in the overall magnetic response. Specifically, we observe a dramatic reversal of the sign of the anomalous Hall effect driven by finite thickness magnetism, which indicates that the film splits into distinct magnetic layers each with a unique electronic signature. These data reveal a delicate dependence of the overall magnetic and electronic response of MnBi2Te4 on the stoichiometry of the top layers. Our study suggests that perturbations resulting from surface oxidation may play a non-trivial role in the stabilization of the quantum anomalous Hall effect in this system and that understanding targeted modifications to the surface may open new routes for engineering novel topological and magnetic responses in this fascinating material., Comment: Accepted in Advanced Functional Materials

Published
2022

42. Genome-wide association meta-analysis identifies risk loci for abdominal aortic aneurysm and highlights PCSK9 as a therapeutic target

Author

Roychowdhury, Tanmoy, Klarin, Derek, Levin, Michael G., Spin, Joshua M., Rhee, Yae Hyun, Deng, Alicia, Headley, Colwyn A., Tsao, Noah L., Gellatly, Corry, Zuber, Verena, Shen, Fred, Hornsby, Whitney E., Laursen, Ina Holst, Verma, Shefali S., Locke, Adam E., Einarsson, Gudmundur, Thorleifsson, Gudmar, Graham, Sarah E., Dikilitas, Ozan, Pattee, Jack W., Judy, Renae L., Pauls-Verges, Ferran, Nielsen, Jonas B., Wolford, Brooke N., Brumpton, Ben M., Dilmé, Jaume, Peypoch, Olga, Juscafresa, Laura Calsina, Edwards, Todd L., Li, Dadong, Banasik, Karina, Brunak, Søren, Jacobsen, Rikke L., Garcia-Barrio, Minerva T., Zhang, Jifeng, Rasmussen, Lars M., Lee, Regent, Handa, Ashok, Wanhainen, Anders, Mani, Kevin, Lindholt, Jes S., Obel, Lasse M., Strauss, Ewa, Oszkinis, Grzegorz, Nelson, Christopher P., Saxby, Katie L., van Herwaarden, Joost A., van der Laan, Sander W., van Setten, Jessica, Camacho, Mercedes, Davis, Frank M., Wasikowski, Rachael, Tsoi, Lam C., Gudjonsson, Johann E., Eliason, Jonathan L., Coleman, Dawn M., Henke, Peter K., Ganesh, Santhi K., Chen, Y. Eugene, Guan, Weihua, Pankow, James S., Pankratz, Nathan, Pedersen, Ole B., Erikstrup, Christian, Tang, Weihong, Hveem, Kristian, Gudbjartsson, Daniel, Gretarsdottir, Solveig, Thorsteinsdottir, Unnur, Holm, Hilma, Stefansson, Kari, Ferreira, Manuel A., Baras, Aris, Kullo, Iftikhar J., Ritchie, Marylyn D., Christensen, Alex H., Iversen, Kasper K., Eldrup, Nikolaj, Sillesen, Henrik, Ostrowski, Sisse R., Bundgaard, Henning, Ullum, Henrik, Burgess, Stephen, Gill, Dipender, Gallagher, Katherine, Sabater-Lleal, Maria, Surakka, Ida, Jones, Gregory T., Bown, Matthew J., Tsao, Philip S., Willer, Cristen J., and Damrauer, Scott M.

Published
2023
Full Text
View/download PDF

43. A fly GWAS for purine metabolites identifies human FAM214 homolog medusa, which acts in a conserved manner to enhance hyperuricemia-driven pathologies by modulating purine metabolism and the inflammatory response

Author

Hilsabeck, Tyler AU, Liu-Bryan, Ru, Guo, Tracy, Wilson, Kenneth A, Bose, Neelanjan, Raftery, Daniel, Beck, Jennifer N, Lang, Sven, Jin, Kelly, Nelson, Christopher S, Oron, Tal, Stoller, Marshall, Promislow, Daniel, Brem, Rachel B, Terkeltaub, Robert, and Kapahi, Pankaj

Subjects
Genetics, Biotechnology, Aetiology, 2.1 Biological and endogenous factors, Inflammatory and immune system, Animals, Humans, Mice, Drosophila melanogaster, Genome-Wide Association Study, Gout, Hyperuricemia, Inflammation, Purines, Uric Acid, Drosophila Proteins, GWAS, Drosophila, Lifespan
Abstract

Elevated serum urate (hyperuricemia) promotes crystalline monosodium urate tissue deposits and gout, with associated inflammation and increased mortality. To identify modifiers of uric acid pathologies, we performed a fly Genome-Wide Association Study (GWAS) on purine metabolites using the Drosophila Genetic Reference Panel strains. We tested the candidate genes using the Drosophila melanogaster model of hyperuricemia and uric acid crystallization ("concretion formation") in the kidney-like Malpighian tubule. Medusa (mda) activity increased urate levels and inflammatory response programming. Conversely, whole-body mda knockdown decreased purine synthesis precursor phosphoribosyl pyrophosphate, uric acid, and guanosine levels; limited formation of aggregated uric acid concretions; and was sufficient to rescue lifespan reduction in the fly hyperuricemia and gout model. Levels of mda homolog FAM214A were elevated in inflammatory M1- and reduced in anti-inflammatory M2-differentiated mouse bone marrow macrophages, and influenced intracellular uric acid levels in human HepG2 transformed hepatocytes. In conclusion, mda/FAM214A acts in a conserved manner to regulate purine metabolism, promotes disease driven by hyperuricemia and associated tissue inflammation, and provides a potential novel target for uric acid-driven pathologies.

Published
2022

44. International Business Education Using Global Virtual Teams: Relationship between Cultural Intelligence, Global Knowledge, and Team Performance

Author

Randazzo-Davis, Maria and Nelson, Christopher

Abstract

Corporate employees must interact with people from different cultures in cross-cultural environments. This study examined the extent that cultural intelligence and global knowledge predicted team performance for university students engaged in collaborative team projects resembling the global corporate work environment. The sample for this study was 2,012 students who participated in the X-Culture Global Virtual Team Project during the spring semester of 2015. Participants were members of 412 teams representing 40 countries and attending 95 universities. Study results indicated that global knowledge and cultural intelligence significantly relate to team performance. Cultural intelligence is a significant partial mediation between global knowledge and team performance in international business courses.

Published
2020

45. Network Analysis

Author

Nelson, Christopher, Masys, Anthony J., Editor-in-Chief, Bichler, Gisela, Advisory Editor, Bourlai, Thirimachos, Advisory Editor, Johnson, Chris, Advisory Editor, Karampelas, Panagiotis, Advisory Editor, Leuprecht, Christian, Advisory Editor, Morse, Edward C., Advisory Editor, Skillicorn, David, Advisory Editor, Yamagata, Yoshiki, Advisory Editor, and Nelson, Christopher

Published
2023
Full Text
View/download PDF

46. Market Share Analysis

Author

Nelson, Christopher, Masys, Anthony J., Editor-in-Chief, Bichler, Gisela, Advisory Editor, Bourlai, Thirimachos, Advisory Editor, Johnson, Chris, Advisory Editor, Karampelas, Panagiotis, Advisory Editor, Leuprecht, Christian, Advisory Editor, Morse, Edward C., Advisory Editor, Skillicorn, David, Advisory Editor, Yamagata, Yoshiki, Advisory Editor, and Nelson, Christopher

Published
2023
Full Text
View/download PDF

47. Scripting an Illicit Strategic Trade Transaction

Author

Nelson, Christopher, Masys, Anthony J., Editor-in-Chief, Bichler, Gisela, Advisory Editor, Bourlai, Thirimachos, Advisory Editor, Johnson, Chris, Advisory Editor, Karampelas, Panagiotis, Advisory Editor, Leuprecht, Christian, Advisory Editor, Morse, Edward C., Advisory Editor, Skillicorn, David, Advisory Editor, Yamagata, Yoshiki, Advisory Editor, and Nelson, Christopher

Published
2023
Full Text
View/download PDF

48. Applying Strategic Trade Analysis

Author

Nelson, Christopher, Masys, Anthony J., Editor-in-Chief, Bichler, Gisela, Advisory Editor, Bourlai, Thirimachos, Advisory Editor, Johnson, Chris, Advisory Editor, Karampelas, Panagiotis, Advisory Editor, Leuprecht, Christian, Advisory Editor, Morse, Edward C., Advisory Editor, Skillicorn, David, Advisory Editor, Yamagata, Yoshiki, Advisory Editor, and Nelson, Christopher

Published
2023
Full Text
View/download PDF

49. Transshipment and Re-export Analysis

Author

Nelson, Christopher, Masys, Anthony J., Editor-in-Chief, Bichler, Gisela, Advisory Editor, Bourlai, Thirimachos, Advisory Editor, Johnson, Chris, Advisory Editor, Karampelas, Panagiotis, Advisory Editor, Leuprecht, Christian, Advisory Editor, Morse, Edward C., Advisory Editor, Skillicorn, David, Advisory Editor, Yamagata, Yoshiki, Advisory Editor, and Nelson, Christopher

Published
2023
Full Text
View/download PDF

50. Mirror Statistics

Author

Nelson, Christopher, Masys, Anthony J., Editor-in-Chief, Bichler, Gisela, Advisory Editor, Bourlai, Thirimachos, Advisory Editor, Johnson, Chris, Advisory Editor, Karampelas, Panagiotis, Advisory Editor, Leuprecht, Christian, Advisory Editor, Morse, Edward C., Advisory Editor, Skillicorn, David, Advisory Editor, Yamagata, Yoshiki, Advisory Editor, and Nelson, Christopher

Published
2023
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results