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2. Exploring Challenges Related to Breast Cancer to Identify Opportunities for Advocacy in Hawassa City, Southern Ethiopia: A Community-Based, Qualitative Study

Author

Netsanet Bogale, Bargude Balta, Gulema Demissie, Dereje Geleta, Michele Rakoff, Brandon Anderson, Natalie Johnson, Lisa Yee, and Lesley Taylor

Subjects
Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

PURPOSEThe aim of this study was to explore breast cancer (BC) challenges to identify opportunities for advocacy in southern Ethiopia in 2022.METHODSTwenty-five participants from four local districts (kebeles) in Hawassa City were selected as key contributors to future work. Semistructured in-depth interviews were held for two clinicians, two local health bureau managers, two media managers, and three religious leaders. Two focus group discussions were conducted: one included six BC survivors and a caregiver; the other included two health extension workers, three members of the Women's Development Group, two community volunteers, one kebele leader, and one traditional healer.RESULTSTo our knowledge, our study was the first time that most participants had assembled. Many referred to patients as victims and BC as a killer disease or curse. Community and religious leaders were concerned about challenges and willing to collaborate. Survivors, providers, and religious leaders were identified as key sources of information, positive messages, and leadership.CONCLUSIONRecommendations for advocacy work in Hawassa include lobbying for BC as a health priority; including BC within the health extension package; initiating programs for earlier detection; educating the community to remove stigmas of the disease and treatments; working with media to disseminate messages that are inclusive of people in remote areas and speaking different languages; improving availability, affordability, and access to care; and assisting patients with psychosocial support. A strategic collaboration between religious leaders and health care providers was identified to increase community awareness and support advocacy for patients.

Published
2023
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3. Frailty status and associated factors among older PLHIV in Southern Ethiopia

Author

Endrias Markos Woldesemayat, Natalie St Clair-Sullivan, Andargachew Kassa, Taye Gari, Keneni Gutema, Nana Chea, Kindie Woubshet, Netsanet Bogale, Amare Assefa, and Jaime Vera

Subjects
Medicine, Science
Abstract

Background Studies addressing frailty are limited in the global south, including Ethiopia. We estimated the prevalence of frailty and associated factors among older people living with HIV (PLHIV) attending a large Comprehensive Specialized Hospital in southern Ethiopia. Methods A systematic sample of 187 PLHIV and 187 HIV-negative controls > 50 years old were recruited between October 1 and November 30, 2021. Data on socio-demographic, behavioural and clinical characteristics were collected using a structured questionnaire. Frailty assessments were completed using the brief frailty instrument (B-FIT-2), which consists of 6 components. Scoring 5–6 points was frail, 2–4 points were pre-frail and below 2 was considered as non-frail. Logistic regression model was used to measure association between variables. Results Median (IQR) age was 53 (50, 80) for PLWH and 59 (55–66) for controls. Prevalence of frailty was 9.1% for PLHIV Versus 5.9% for controls. A significant proportion of PLHIV was pre-frail; 141 (75.4%) compared to controls 110 (58.8%). Pre-frailty status was associated with HIV diagnosis (adjusted odds ratio (aOR) 4.2; 95% CI 1.8–9.9), low age (aOR 0.3; 95% CI 0.1–0.6), lower educational attainment (aOR 2.2; 95% CI 1.0–4.9), being farmer (aOR 3.2; 95% CI 1.0–10.2) and having high or low body mass index (BMI) (aOR 11.3; 95% CI 4.0–25.8). HIV diagnosis (aOR 9.7; 95% CI 1.6–56.8), age (aOR 0.2; 95% CI 0.1–0.7), lower educational attainment (aOR 5.2; 95% CI 1.5–18.2), single status (aOR 4.2; 95% CI 1.3–13.6), farmer (aOR 19.5; 95% CI 3.5–109.1) and high or low BMI (aOR 47.3; 95% CI 13.8–161.9) predicted frailty. Conclusion A high proportion of frailty and pre-frailty was observed in a cohort of older PLHIV attending care in Southern Ethiopia. Future research should focus on interventions targeting factors associated with frailty.

Published
2023

4. Descriptive epidemiology of gynaecological cancers in southern Ethiopia: retrospective cross-sectional review

Author

Netsanet Bogale, Achamyelesh Gebretsadik, and Dubale Dulla

Subjects
Medicine
Abstract

Objective To determine the epidemiology of gynaecological cancer among patients treated at Hawassa University Comprehensive and Specialized Hospital (HUCSH) from 2013 to 2019.Design A retrospective cross-sectional review.Setting, participants, and outcome measure A total of 3002 patients’ cards with a diagnosis of cancer at a tertiary hospital named HUCSH were reviewed between February and May 2020. HUCSH is the only oncological care centre in the southern region of Ethiopia. Of this all-gynaecological cancer charts were extracted and descriptive and trend analyses were done. The review was conducted between February and May 2020.Result Out of all 3002 cancer cases, 522 (17.4%) cases of gynaecological cancers were identified in 7 years. Cervical cancer accounted for 385 (73.8%) of all gynaecological cancers in this study, the next most common gynaecological cancers were ovarian cancer 55(10.5%) and endometrial cancer 51(9.8%), respectively. The mean (SD) age was 44.84 (12.23). Trends of all identified gynaecological cancers showed continuous increments of caseload year to year. Since 2016 increment of cervical cancer is drastically vertical compared with others.Conclusion Despite the limited use of a registration and referral system in primary health institutions, the burden of gynaecological cancers has increased over time. Treatment steps should be taken as soon as possible after a cancer diagnosis to prevent the disease from progressing.

Published
2022
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6. Epidemiological Trends of Breast Cancer in Southern Ethiopia: A Seven-Year Retrospective Review

Author

Achamyelesh Gebretsadik, Netsanet Bogale, and Dereje. G Negera

Subjects
Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

Introduction African women are affected by cancer at an early age of their productivity. However, the exact prevalence and incidence of cancer, including breast cancer is not known in most sub-Saharan African countries, including Ethiopia because of lack of well-established cancer registry. This study aims to assess the epidemiology of breast cancer at Hawassa University Comprehensive Specialized Hospital (HUCSH), the biggest referral hospital with cancer treatment center serving the southern part of the country. Methods Retrospective review of charts of all patients with a diagnosis of breast cancer between 2013 and 2019 at HUCSH was conducted. A standardized questionnaire was used to collect relevant data that include sociodemographic, symptoms, type of diagnosis, treatment, and outcomes. Data were entered using epidata version 3.1 and analyzed using MS Excel and SPSS version 20. Results Five hundred fifty-nine (18.6%) breast cancer cases were retrieved in 7 years between 2013 and 2019. Of this, 548 (98%) were women. The median ages of the patents were 38 years. Invasive ductal carcinoma was the leading 309 (55.3%) histologic type followed by 185 (33.1%) lobular carcinoma. One hundred seventy-seven (31.7%) were moderately differentiated and 155 (27.7%) were poorly differentiated. Three hundred seventy-two (66.5%) were advanced breast cancer (Stages III and IV). Trends of breast cancer showed the case load is continuously increasing except with a slight reduction of cases in between 2015 and 2016. The majority were advanced breast cancer occurring at an early age by the time diagnosis made. Invasive ductal carcinomas were the predominant one. The trend also showed a continuous increment of cancer case load. Therefore, cancer registration center establishment, community awareness creation, and intensive early detection strategy are mandatory.

Published
2021
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7. Economic Burden of Cancer on Cancer Patients Treated at Hawassa University Comprehensive Specialized Hospital

Author

Lalisa Gemechu Bona, Dereje Geleta, Dubale Dulla, Bedilu Deribe, Mohammed Ayalew, Girma Ababi, Netsanet Bogale, Kurabachew Mengistu, Anteneh Gadissa, and Achamyelesh Gebretsadik

Subjects
Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

Cancer causes the highest economic loss of all of the leading 15 causes of death worldwide. The economic loss includes the loss of income and the expenses associated with health care costs. The Low awareness of the community toward cancer, the inadequacy of professionals and service providers, and the high budget consuming nature of the treatments are creating a great burden on the cancer patients. The objective of this study was to calculate patient side cancer treatment cost and to assess the contributing factors, among the cancer patients who were treated at Hawassa University Comprehensive Specialized Hospital. The health facility based cross-sectional study design was employed using a consecutive sampling technique. Questionnaires was used to collect primary data; while chart was used to collect the secondary data. Indirect costs incurred on these patients due to off job days were checked. Descriptive and inferential statistics were applied to illustrate the data. On average, $209.99 was spent on treatment by each cancer patients. Of these, medication cost is the highest ($20.77, IQR = 0.53-112.56) from the direct medical costs, and transportation cost is the highest ($58.33, IQR = 22.0-131.67) from the indirect medical costs. Inpatients paid $245.16 (IQR = 147.64-439.20); while outpatients paid $147.37 (IQR = 81.42-240.50). The patients lose about 55.99% of their average annual income. Outpatients pay $0, 92 less than in patients ( P = 0.00, CI -0.72-0.34), and the cost increases by $0.2 for the patients who came from Oromia. The cost of transportation and medication were the one which were significantly affecting the burden; but the total cost of treatment was lesser when compared to similar studies done in different areas. The cost balances toward the patients who came from the Oromiya region. Treatment service has to be extended to West Arsi Zone to minimize the cost of transportation and awareness about cancer is needed in the first place and due attention has to be given to thyroid cancer. Furthermore, facility side study should be done to see the complete picture of the burden.

Published
2021
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8. Prevalence and Predictor of Cervical Cancer Screening Service Uptake Among Women Aged 25 Years and Above in Sidama Zone, Southern Ethiopia, Using Health Belief Model

Author

Ermias Yunkura Gemeda MPH, Belayneh Bekele Kare MPH, Dereje Geleta Negera MPH, Lalisa Gemechu Bona MSc, Bedilu Deribe Derese MSc, Netsanet Bogale Akale MD, Kurabachew Mengistu Kebede MSc, Dubale Dulla Koboto MSc, and Achamyelesh Gebretsadik Tekle PhD

Subjects
Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

Cervical cancer is the fourth most common cancer affecting women worldwide, and the second leading cancer in Ethiopia. Screening gives protective benefits associated with a reduction in the incidence of invasive cervical cancer and mortality. However, the level of cervical cancer screening uptake is not well document in the country. This study aimed to determine the prevalence and predictors of cervical cancer screening service uptake among women aged 25 years and above in Sidama zone, southern Ethiopia, 2019. A cross-sectional study was conducted among 838 women aged 25 and above years by using an interviewer-administered questionnaire. Multi-stage sampling technique was employed to identify households with women age of 25 and above years who were residing in the selected kebele for more than 6 months. Descriptive and multivariable logistic regression done. P-value

Published
2020
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9. Global, regional, and national burden of disorders affecting the nervous system, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021

Author

Steinmetz, Jaimie D, Seeher, Katrin Maria, Schiess, Nicoline, Nichols, Emma, Cao, Bochen, Servili, Chiara, Cavallera, Vanessa, Cousin, Ewerton, Hagins, Hailey, Moberg, Madeline E, Mehlman, Max L, Abate, Yohannes Habtegiorgis, Abbas, Jaffar, Abbasi, Madineh Akram, Abbasian, Mohammadreza, Abbastabar, Hedayat, Abdelmasseh, Michael, Abdollahi, Mohammad, Abdollahi, Mozhan, Abdollahifar, Mohammad-Amin, Abd-Rabu, Rami, Abdulah, Deldar Morad, Abdullahi, Auwal, Abedi, Aidin, Abedi, Vida, Abeldańo Zuńiga, Roberto Ariel, Abidi, Hassan, Abiodun, Olumide, Aboagye, Richard Gyan, Abolhassani, Hassan, Aboyans, Victor, Abrha, Woldu Aberhe, Abualhasan, Ahmed, Abu-Gharbieh, Eman, Aburuz, Salahdein, Adamu, Lawan Hassan, Addo, Isaac Yeboah, Adebayo, Oladimeji M, Adekanmbi, Victor, Adekiya, Tayo Alex, Adikusuma, Wirawan, Adnani, Qorinah Estiningtyas Sakilah, Adra, Saryia, Afework, Tsion, Afolabi, Aanuoluwapo Adeyimika, Afraz, Ali, Afzal, Saira, Aghamiri, Shahin, Agodi, Antonella, Agyemang-Duah, Williams, Ahinkorah, Bright Opoku, Ahmad, Aqeel, Ahmad, Danish, Ahmad, Sajjad, Ahmadzade, Amir Mahmoud, Ahmed, Ali, Ahmed, Ayman, Ahmed, Haroon, Ahmed, Jivan Qasim, Ahmed, Luai A, Ahmed, Muktar Beshir, Ahmed, Syed Anees, Ajami, Marjan, Aji, Budi, Ajumobi, Olufemi, Akade, Seyed Esma'il, Akbari, Morteza, Akbarialiabad, Hossein, Akhlaghi, Shiva, Akinosoglou, Karolina, Akinyemi, Rufus Olusola, Akonde, Maxwell, Al Hasan, Syed Mahfuz, Alahdab, Fares, AL-Ahdal, Tareq Mohammed Ali, Al-amer, Rasmieh Mustafa, Albashtawy, Mohammed, AlBataineh, Mohammad T, Aldawsari, Khalifah A, Alemi, Hediyeh, Alemi, Sharifullah, Algammal, Abdelazeem M, Al-Gheethi, Adel Ali Saeed, Alhalaiqa, Fadwa Alhalaiqa Naji, Alhassan, Robert Kaba, Ali, Abid, Ali, Endale Alemayehu, Ali, Liaqat, Ali, Mohammed Usman, Ali, Musa Mohammed, Ali, Rafat, Ali, Shahid, Ali, Syed Shujait Shujait, Ali, Zahid, Alif, Sheikh Mohammad, Alimohamadi, Yousef, Aliyi, Ahmednur Adem, Aljofan, Mohamad, Aljunid, Syed Mohamed, Alladi, Suvarna, Almazan, Joseph Uy, Almustanyir, Sami, Al-Omari, Basem, Alqahtani, Jaber S, Alqasmi, Ibrahim, Alqutaibi, Ahmed Yaseen, Al-Shahi Salman, Rustam, Altaany, Zaid, Al-Tawfiq, Jaffar A, Altirkawi, Khalid A, Alvis-Guzman, Nelson, Al-Worafi, Yaser Mohammed, Aly, Hany, Aly, Safwat, Alzoubi, Karem H, Amani, Reza, Amindarolzarbi, Alireza, Amiri, Sohrab, Amirzade-Iranaq, Mohammad Hosein, Amu, Hubert, Amugsi, Dickson A, Amusa, Ganiyu Adeniyi, Amzat, Jimoh, Ancuceanu, Robert, Anderlini, Deanna, Anderson, David B, Andrei, Catalina Liliana, Androudi, Sofia, Angappan, Dhanalakshmi, Angesom, Teklit W, Anil, Abhishek, Ansari-Moghaddam, Alireza, Anwer, Razique, Arafat, Mosab, Aravkin, Aleksandr Y, Areda, Demelash, Ariffin, Hany, Arifin, Hidayat, Arkew, Mesay, Ärnlöv, Johan, Arooj, Mahwish, Artamonov, Anton A, Artanti, Kurnia Dwi, Aruleba, Raphael Taiwo, Asadi-Pooya, Ali A, Asena, Tilahun Ferede, Asghari-Jafarabadi, Mohammad, Ashraf, Muhammad, Ashraf, Tahira, Atalell, Kendalem Asmare, Athari, Seyyed Shamsadin, Atinafu, Bantalem Tilaye Tilaye, Atorkey, Prince, Atout, Maha Moh'd Wahbi, Atreya, Alok, Aujayeb, Avinash, Avan, Abolfazl, Ayala Quintanilla, Beatriz Paulina, Ayatollahi, Haleh, Ayinde, Olatunde O, Ayyoubzadeh, Seyed Mohammad, Azadnajafabad, Sina, Azizi, Zahra, Azizian, Khalil, Azzam, Ahmed Y, Babaei, Mahsa, Badar, Muhammad, Badiye, Ashish D, Baghdadi, Soroush, Bagherieh, Sara, Bai, Ruhai, Baig, Atif Amin, Balakrishnan, Senthilkumar, Balalla, Shivanthi, Baltatu, Ovidiu Constantin, Banach, Maciej, Bandyopadhyay, Soham, Banerjee, Indrajit, Baran, Mehmet Firat, Barboza, Miguel A, Barchitta, Martina, Bardhan, Mainak, Barker-Collo, Suzanne Lyn, Bärnighausen, Till Winfried, Barrow, Amadou, Bashash, Davood, Bashiri, Hamideh, Bashiru, Hameed Akande, Basiru, Afisu, Basso, João Diogo, Basu, Sanjay, Batiha, Abdul-Monim Mohammad, Batra, Kavita, Baune, Bernhard T, Bedi, Neeraj, Begde, Ahmet, Begum, Tahmina, Behnam, Babak, Behnoush, Amir Hossein, Beiranvand, Maryam, Béjot, Yannick, Bekele, Alehegn, Belete, Melaku Ashagrie, Belgaumi, Uzma Iqbal, Bemanalizadeh, Maryam, Bender, Rose G, Benfor, Bright, Bennett, Derrick A, Bensenor, Isabela M, Berice, Betyna, Bettencourt, Paulo J G, Beyene, Kebede A, Bhadra, Abhishek, Bhagat, Devidas S, Bhangdia, Kayleigh, Bhardwaj, Nikha, Bhardwaj, Pankaj, Bhargava, Ashish, Bhaskar, Sonu, Bhat, Ajay Nagesh, Bhat, Vivek, Bhatti, Gurjit Kaur, Bhatti, Jasvinder Singh, Bhatti, Rajbir, Bijani, Ali, Bikbov, Boris, Bilalaga, Mariah Malak, Biswas, Atanu, Bitaraf, Saeid, Bitra, Veera R, Bjørge, Tone, Bodolica, Virginia, Bodunrin, Aadam Olalekan, Boloor, Archith, Braithwaite, Dejana, Brayne, Carol, Brenner, Hermann, Briko, Andrey, Bringas Vega, Maria L, Brown, Julie, Budke, Christine M, Buonsenso, Danilo, Burkart, Katrin, Burns, Richard A, Bustanji, Yasser, Butt, Muhammad Hammad, Butt, Nadeem Shafique, Butt, Zahid A, Cabral, Lucas Scotta, Caetano dos Santos, Florentino Luciano, Calina, Daniela, Campos-Nonato, Ismael R, Cao, Chao, Carabin, Hélène, Cárdenas, Rosario, Carreras, Giulia, Carvalho, Andre F, Castańeda-Orjuela, Carlos A, Casulli, Adriano, Catalá-López, Ferrán, Catapano, Alberico L, Caye, Arthur, Cegolon, Luca, Cenderadewi, Muthia, Cerin, Ester, Chacón-Uscamaita, Pamela R, Chan, Jeffrey Shi Kai, Chanie, Gashaw Sisay, Charan, Jaykaran, Chattu, Vijay Kumar, Chekol Abebe, Endeshaw, Chen, Hui, Chen, Jianqi, Chi, Gerald, Chichagi, Fatemeh, Chidambaram, Saravana Babu, Chimoriya, Ritesh, Ching, Patrick R, Chitheer, Abdulaal, Chong, Yuen Yu, Chopra, Hitesh, Choudhari, Sonali Gajanan, Chowdhury, Enayet Karim, Chowdhury, Rajiv, Christensen, Hanne, Chu, Dinh-Toi, Chukwu, Isaac Sunday, Chung, Eric, Coberly, Kaleb, Columbus, Alyssa, Comachio, Josielli, Conde, Joao, Cortesi, Paolo Angelo, Costa, Vera Marisa, Couto, Rosa A S, Criqui, Michael H, Cruz-Martins, Natália, Dabbagh Ohadi, Mohammad Amin, Dadana, Sriharsha, Dadras, Omid, Dai, Xiaochen, Dai, Zhaoli, D'Amico, Emanuele, Danawi, Hadi A, Dandona, Lalit, Dandona, Rakhi, Darwish, Amira Hamed, Das, Saswati, Das, Subasish, Dascalu, Ana Maria, Dash, Nihar Ranjan, Dashti, Mohsen, De la Hoz, Fernando Pio, de la Torre-Luque, Alejandro, De Leo, Diego, Dean, Frances E, Dehghan, Amin, Dehghan, Azizallah, Dejene, Hiwot, Demant, Daniel, Demetriades, Andreas K, Demissie, Solomon, Deng, Xinlei, Desai, Hardik Dineshbhai, Devanbu, Vinoth Gnana Chellaiyan, Dhama, Kuldeep, Dharmaratne, Samath Dhamminda, Dhimal, Meghnath, Dias da Silva, Diana, Diaz, Daniel, Dibas, Mahmoud, Ding, Delaney D, Dinu, Monica, Dirac, M Ashworth, Diress, Mengistie, Do, Thanh Chi, Do, Thao Huynh Phuong, Doan, Khanh Duy Khanh, Dodangeh, Milad, Doheim, Mohamed Fahmy, Dokova, Klara Georgieva, Dongarwar, Deepa, Dsouza, Haneil Larson, Dube, John, Duraisamy, Senbagam, Durojaiye, Oyewole Christopher, Dutta, Sulagna, Dziedzic, Arkadiusz Marian, Edinur, Hisham Atan, Eissazade, Negin, Ekholuenetale, Michael, Ekundayo, Temitope Cyrus, El Nahas, Nevine, El Sayed, Iman, Elahi Najafi, Mohammad Amin, Elbarazi, Iffat, Elemam, Noha Mousaad, Elgar, Frank J, Elgendy, Islam Y, Elhabashy, Hala Rashad, Elhadi, Muhammed, Elilo, Legesse Tesfaye, Ellenbogen, Richard G, Elmeligy, Omar Abdelsadek Abdou, Elmonem, Mohamed A, Elshaer, Mohammed, Elsohaby, Ibrahim, Emamverdi, Mehdi, Emeto, Theophilus I, Endres, Matthias, Esezobor, Christopher Imokhuede, Eskandarieh, Sharareh, Fadaei, Abdolmajid, Fagbamigbe, Adeniyi Francis, Fahim, Ayesha, Faramarzi, Ali, Fares, Jawad, Farjoud Kouhanjani, Mohsen, Faro, Andre, Farzadfar, Farshad, Fatehizadeh, Ali, Fathi, Mobina, Fathi, Saeid, Fatima, Syeda Anum Fatima, Feizkhah, Alireza, Fereshtehnejad, Seyed-Mohammad, Ferrari, Alize J, Ferreira, Nuno, Fetensa, Getahun, Firouraghi, Neda, Fischer, Florian, Fonseca, Ana Catarina, Force, Lisa M, Fornari, Arianna, Foroutan, Behzad, Fukumoto, Takeshi, Gadanya, Muktar A, Gaidhane, Abhay Motiramji, Galali, Yaseen, Galehdar, Nasrin, Gan, Quan, Gandhi, Aravind P, Ganesan, Balasankar, Gardner, William M, Garg, Naval, Gau, Shuo-Yan, Gautam, Rupesh K, Gebre, Teshome, Gebrehiwot, Mesfin, Gebremeskel, Gebreamlak Gebremedhn, Gebreslassie, Haftay Gebremedhin, Getacher, Lemma, Ghaderi Yazdi, Bardiya, Ghadirian, Fataneh, Ghaffarpasand, Fariborz, Ghanbari, Reza, Ghasemi, MohammadReza, Ghazy, Ramy Mohamed, Ghimire, Sailaja, Gholami, Ali, Gholamrezanezhad, Ali, Ghotbi, Elena, Ghozy, Sherief, Gialluisi, Alessandro, Gill, Paramjit Singh, Glasstetter, Logan M, Gnedovskaya, Elena V, Golchin, Ali, Golechha, Mahaveer, Goleij, Pouya, Golinelli, Davide, Gomes-Neto, Mansueto, Goulart, Alessandra C, Goyal, Anmol, Gray, Richard J, Grivna, Michal, Guadie, Habtamu Alganeh, Guan, Bin, Guarducci, Giovanni, Guicciardi, Stefano, Gunawardane, Damitha Asanga, Guo, Hanbing, Gupta, Bhawna, Gupta, Rajeev, Gupta, Sapna, Gupta, Veer Bala, Gupta, Vivek Kumar, Gutiérrez, Reyna Alma, Habibzadeh, Farrokh, Hachinski, Vladimir, Haddadi, Rasool, Hadei, Mostafa, Hadi, Najah R, Haep, Nils, Haile, Teklehaimanot Gereziher, Haj-Mirzaian, Arvin, Hall, Brian J, Halwani, Rabih, Hameed, Sajid, Hamiduzzaman, Mohammad, Hammoud, Ahmad, Han, Hannah, Hanifi, Nasrin, Hankey, Graeme J, Hannan, Md. Abdul, Hao, Junwei, Harapan, Harapan, Hareru, Habtamu Endashaw, Hargono, Arief, Harlianto, Netanja I., Haro, Josep Maria, Hartman, Nicholas Nathaniel, Hasaballah, Ahmed I., Hasan, Faizul, Hasani, Hamidreza, Hasanian, Mohammad, Hassan, Amr, Hassan, Shoaib, Hassanipour, Soheil, Hassankhani, Hadi, Hassen, Mohammed Bheser, Haubold, Johannes, Hay, Simon I, Hayat, Khezar, Hegazy, Mohamed I, Heidari, Golnaz, Heidari, Mohammad, Heidari-Soureshjani, Reza, Hesami, Hamed, Hezam, Kamal, Hiraike, Yuta, Hoffman, Howard J, Holla, Ramesh, Hopf, Kathleen Pillsbury, Horita, Nobuyuki, Hossain, Md Mahbub, Hossain, Md. Belal, Hossain, Sahadat, Hosseinzadeh, Hassan, Hosseinzadeh, Mehdi, Hostiuc, Sorin, Hu, Chengxi, Huang, Junjie, Huda, Md. Nazmul, Hussain, Javid, Hussein, Nawfal R, Huynh, Hong-Han, Hwang, Bing-Fang, Ibitoye, Segun Emmanuel, Ilaghi, Mehran, Ilesanmi, Olayinka Stephen, Ilic, Irena M, Ilic, Milena D, Immurana, Mustapha, Iravanpour, Farideh, Islam, Sheikh Mohammed Shariful, Ismail, Faisal, Iso, Hiroyasu, Isola, Gaetano, Iwagami, Masao, Iwu, Chidozie C D, Iyer, Mahalaxmi, Jaan, Ali, Jacob, Louis, Jadidi-Niaragh, Farhad, Jafari, Mahboobeh, Jafarinia, Morteza, Jafarzadeh, Abdollah, Jahankhani, Kasra, Jahanmehr, Nader, Jahrami, Haitham, Jaiswal, Abhishek, Jakovljevic, Mihajlo, Jamora, Roland Dominic G, Jana, Somnath, Javadi, Nilofer, Javed, Saad, Javeed, Saad, Jayapal, Sathish Kumar, Jayaram, Shubha, Jiang, Heng, Johnson, Catherine Owens, Johnson, Walter D, Jokar, Mohammad, Jonas, Jost B, Joseph, Abel, Joseph, Nitin, Joshua, Charity Ehimwenma, Jürisson, Mikk, Kabir, Ali, Kabir, Zubair, Kabito, Gebisa Guyasa, Kadashetti, Vidya, Kafi, Fatemeh, Kalani, Rizwan, Kalantar, Farnaz, Kaliyadan, Feroze, Kamath, Ashwin, Kamath, Sagarika, Kanchan, Tanuj, Kandel, Amit, Kandel, Himal, Kanmodi, Kehinde Kazeem, Karajizadeh, Mehrdad, Karami, Jafar, Karanth, Shama D, Karaye, Ibraheem M, Karch, André, Karimi, Aliasghar, Karimi, Hanie, Karimi Behnagh, Arman, Kasraei, Hengameh, Kassebaum, Nicholas J, Kauppila, Joonas H, Kaur, Harkiran, Kaur, Navjot, Kayode, Gbenga A, Kazemi, Foad, Keikavoosi-Arani, Leila, Keller, Cathleen, Keykhaei, Mohammad, Khadembashiri, Mohammad Amin, Khader, Yousef Saleh, Khafaie, Morteza Abdullatif, Khajuria, Himanshu, Khalaji, Amirmohammad, Khamesipour, Faham, Khammarnia, Mohammad, Khan, Maseer, Khan, Moien AB, Khan, Yusra H, Khan Suheb, Mahammed Ziauddin, Khanmohammadi, Shaghayegh, Khanna, Tripti, Khatab, Khaled, Khatatbeh, Haitham, Khatatbeh, Moawiah Mohammad, Khateri, Sorour, Khatib, Mahalaqua Nazli, Khayat Kashani, Hamid Reza, Khonji, Mohammad Saeid, khorashadizadeh, Fatemeh, Khormali, Moein, Khubchandani, Jagdish, Kian, Saeid, Kim, Grace, Kim, Jihee, Kim, Min Seo, Kim, Yun Jin, 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and Dua, Tarun

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10. Global Burden of Cardiovascular Diseases and Risks, 1990-2022

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Mensah, George A., primary, Fuster, Valentin, additional, Murray, Christopher J.L., additional, Roth, Gregory A., additional, Mensah, George A., additional, Abate, Yohannes Habtegiorgis, additional, Abbasian, Mohammadreza, additional, Abd-Allah, Foad, additional, Abdollahi, Ashkan, additional, Abdollahi, Mohammad, additional, Abdulah, Deldar Morad, additional, Abdullahi, Auwal, additional, Abebe, Ayele Mamo, additional, Abedi, Aidin, additional, Abedi, Armita, additional, Abiodun, Olugbenga Olusola, additional, Ali, Hiwa Abubaker, additional, Abu-Gharbieh, Eman, additional, Abu-Rmeileh, Niveen M.E., additional, Aburuz, Salahdein, additional, Abushouk, Abdelrahman I., additional, Abu-Zaid, Ahmed, additional, Adane, Tigist Demssew, additional, Adderley, Nicola J., additional, Adebayo, Oladimeji M., additional, Aden, Bashir, additional, Adeyeoluwa, Temitayo Esther, additional, Adeyomoye, Olorunsola Israel, additional, Sakilah Adnani, Qorinah Estiningtyas, additional, Afrashteh, Fatemeh, additional, Afyouni, Shadi, additional, Afzal, Saira, additional, Agasthi, Pradyumna, additional, Agodi, Antonella, additional, Aguilera Arriagada, Constanza Elizabeth, additional, Agyemang-Duah, Williams, additional, Ahinkorah, Bright Opoku, additional, Ahmad, Aqeel, additional, Ahmad, Danish, additional, Ahmad, Firdos, additional, Ahmad, Muayyad M., additional, Ahmed, Ayman, additional, Ahmed, Haroon, additional, Ahmed, Muktar Beshir, additional, Ahmed, Syed Anees, additional, Ajami, Marjan, additional, Akinosoglou, Karolina, additional, Ala, Moein, additional, Ali AL-Ahdal, Tareq Mohammed, additional, Alalalmeh, Samer O., additional, Al-Aly, Ziyad, additional, Alam, Nazmul, additional, Al-amer, Rasmieh Mustafa, additional, Alashi, Alaa, additional, Albashtawy, Mohammed, additional, AlBataineh, Mohammad T., additional, Alema, Haileselasie Berhane, additional, Alemi, Sharifullah, additional, Alemu, Yihun Mulugeta, additional, Saeed Al-Gheethi, Adel Ali, additional, Alhabib, Khalid F., additional, Naji Alhalaiqa, Fadwa Alhalaiqa, additional, Ali, Mohammed Usman, additional, Ali, Rafat, additional, pursuing, PhD., additional, Shujait Ali, Syed Shujait, additional, Alicandro, Gianfranco, additional, Alikhani, Reyhaneh, additional, Aljunid, Syed Mohamed, additional, Alla, François, additional, Almahmeed, Wael, additional, Al-Marwani, Sabah, additional, Alonso, Jordi, additional, Al-Raddadi, Rajaa M., additional, Alvi, Farrukh Jawad, additional, Alvis-Guzman, Nelson, additional, Alvis-Zakzuk, Nelson J., additional, Alwafi, Hassan, additional, Aly, Hany, additional, Amegbor, Prince M., additional, Amin, Tarek Tawfik, additional, Amindarolzarbi, Alireza, additional, Amini-Rarani, Mostafa, additional, Amiri, Sohrab, additional, Ammirati, Enrico, additional, Anand, Tanu, additional, Ancuceanu, Robert, additional, Anderlini, Deanna, additional, Anil, Abhishek, additional, Ansari, Golnoosh, additional, Anyanwu, Philip Emeka, additional, Anyasodor, Anayochukwu Edward, additional, Carace Apostol, Geminn Louis, additional, Arabloo, Jalal, additional, Arafat, Mosab, additional, Aravkin, Aleksandr Y., additional, Aremu, Olatunde, additional, Armocida, Benedetta, additional, Ärnlöv, Johan, additional, Arowosegbe, Oluwaseyi Olalekan, additional, Artamonov, Anton A., additional, Artanti, Kurnia Dwi, additional, Arulappan, Judie, additional, Aruleba, Idowu Thomas, additional, Arumugam, Ashokan, additional, Aryan, Zahra, additional, Asghari-Jafarabadi, Mohammad, additional, Astell-Burt, Thomas, additional, Ataei, Mahshid, additional, Athar, Mohammad, additional, Atreya, Alok, additional, Aujayeb, Avinash, additional, Awotidebe, Adedapo Wasiu, additional, Aynalem, Amdehiwot A., additional, Azizi, Zahra, additional, Azzam, Ahmed Y., additional, Babu, Abraham Samuel, additional, Badar, Muhammad, additional, Bader, Feras, additional, Badiye, Ashish D., additional, Bagga, Arvind, additional, Bagherieh, Sara, additional, Asl, Farshad Bahrami, additional, Bai, 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Nazila, additional, Rezaeian, Mohsen, additional, Ribeiro, Antonio Luiz P., additional, Ribeiro, Daniela, additional, Rikhtegar, Reza, additional, Roever, Leonardo, additional, Romadlon, Debby Syahru, additional, Ronfani, Luca, additional, Sekhar Rout, Himanshu Sehar, additional, Roy, Nitai, additional, Roy, Priyanka, additional, Rynkiewicz, Andrzej, additional, Saad, Aly M.A., additional, Saadatian, Zahra, additional, Sabour, Siamak, additional, Sacco, Simona, additional, Sachdeva, Rajesh, additional, Saddik, Basema, additional, Sadeghi, Erfan, additional, Saeed, Umar, additional, Safaeinejad, Fahimeh, additional, Sharif-Askari, Fatemeh Saheb, additional, Sharif-Askari, Narjes Saheb, additional, Sahebkar, Amirhossein, additional, Sahoo, Soumya Swaroop, additional, Sajedi, Seyed Aidin, additional, Sajid, Mirza Rizwan, additional, Sakshaug, Joseph W., additional, Salam, Nasir, additional, Salami, Afeez Abolarinwa, additional, Saleh, Mohamed A., additional, Salehi, Sana, additional, Salem, Marwa Rashad, additional, Salem, Mohammed Z.Y., additional, Samadzadeh, Sara, additional, Samargandy, Saad, additional, Samuel, Vijaya Paul, additional, Samy, Abdallah M., additional, Sanabria, Juan, additional, Sanjeev, Rama Krishna, additional, Santric-Milicevic, Milena M., additional, Nadeem Saqib, Muhammad Arif, additional, Sarasmita, Made Ary, additional, Saravanan, Aswini, additional, Sarikhani, Yaser, additional, Sarkar, Tanmay, additional, Sarmiento-Suárez, Rodrigo, additional, Sarode, Gargi Sachin, additional, Sarode, Sachin C., additional, Sathish, Thirunavukkarasu, additional, Sathyanarayan, Anudeep, additional, Sawhney, Monika, additional, Sayyah, Mehdi, additional, Scarmeas, Nikolaos, additional, Schaarschmidt, Benedikt Michael, additional, Schuermans, Art, additional, Schumacher, Austin E., additional, Schutte, Aletta Elisabeth, additional, Schwebel, David C., additional, Sedighi, Mansour, additional, Seidu, Abdul-Aziz, additional, Semnani, Farbod, additional, Senapati, Sabyasachi, additional, Sengupta, Pallav, additional, Senthilkumaran, Subramanian, additional, Sepanlou, Sadaf G., additional, Sethi, Yashendra, additional, Seyedi, Seyed Arsalan, additional, Seylani, Allen, additional, Shabany, Maryam, additional, Shafeghat, Melika, additional, Shafie, Mahan, additional, Shah, Pritik A., additional, Shahbandi, Ataollah, additional, Shahid, Izza, additional, Shahid, Samiah, additional, Shahid, Wajeehah, additional, Shahwan, Moyad Jamal, additional, Shaikh, Masood Ali, additional, Sham, Sunder, additional, Shamim, Muhammad Aaqib, additional, Shanawaz, Mohd, additional, Sharfaei, Sadaf, additional, Sharifan, Amin, additional, Sharifi-Rad, Javad, additional, Sharma, Purva, additional, Sharma, Saurab, additional, Sharma, Ujjawal, additional, Sharma, Vishal, additional, Sheikh, Aziz, additional, Shiferaw, Desalegn Shiferaw, additional, Shigematsu, Mika, additional, Shin, Min-Jeong, additional, Shiri, Rahman, additional, Shishani, Kawkab, additional, Shittu, Aminu, additional, Shiue, Ivy, additional, Shivakumar, K.M., additional, Shrestha, Sunil, additional, Shuval, Kerem, additional, Sibhat, Migbar Mekonnen, additional, Sigfusdottir, Inga Dora, additional, Simpson, Colin R., additional, Singh, Abhinav, additional, Singh, Aditya, additional, Singh, Ambrish, additional, Singh, Jasvinder A., additional, Singh, Paramdeep, additional, Singh, Rajat, additional, Singh, Surjit, additional, Siraj, Md Shahjahan, additional, Skryabin, Valentin Yurievich, additional, Skryabina, Anna Aleksandrovna, additional, Sleet, David A., additional, Soleimani, Hamidreza, additional, Solikhah, Solikhah, additional, Soliman, Sameh S.M., additional, Son, Juyeon, additional, Song, Suhang, additional, Song, Yi, additional, Soriano, Joan B., additional, Spartalis, Michael, additional, Sreeramareddy, Chandrashekhar T., additional, Stafford, Lauryn K., additional, Stark, Benjamin A., additional, Steiropoulos, Paschalis, additional, Stortecky, Stefan, additional, Abdulkader, Rizwan Suliankatchi, additional, Sultana, Abida, additional, Sundström, Johan, additional, Swain, Chandan Kumar, additional, Damavandi, Payam Tabaee, additional, Tabatabaei, Seyyed Mohammad, additional, Malazy, Ozra Tabatabaei, additional, Tabatabaeizadeh, Seyed-Amir, additional, Tabatabai, Shima, additional, Tabb, Karen M., additional, Tabish, Mohammad, additional, Tabuchi, Takahiro, additional, Tadese, Fentaw, additional, Abkenar, Yasaman Taheri, additional, Taiba, Jabeen, additional, Talaat, Iman M., additional, Tampa, Mircea, additional, Lukenze Tamuzi, Jacques J.L., additional, Tan, Ker-Kan, additional, Tang, Haosu, additional, Tarkang, Elvis Enowbeyang, additional, Tat, Nathan Y., additional, Tavangar, Seyed Mohammad, additional, Tehrani, Hadi, additional, Teimoori, Mojtaba, additional, Temsah, Mohamad-Hani, additional, Hani Temsah, Reem Mohamad, additional, Teramoto, Masayuki, additional, Thangaraju, Pugazhenthan, additional, Thankappan, Kavumpurathu Raman, additional, Thapa, Rajshree, additional, Thapar, Rekha, additional, Thavamani, Aravind, additional, Thayakaran, Rasiah, additional, Thomas, Nikhil Kenny, additional, Tian, Jing, additional, Tichopad, Ales, additional, Tillawi, Tala, additional, Tonelli, Marcello, additional, Topor-Madry, Roman, additional, Touvier, Mathilde, additional, Tovani-Palone, Marcos Roberto, additional, Tran, Jasmine T., additional, Tran, Nghia Minh, additional, Van Tran, Phu, additional, Trihandini, Indang, additional, Tripathi, Avnish, additional, Tromans, Samuel Joseph, additional, Truong, Vien T., additional, Tri Tai Truyen, Thien Tan, additional, Tsatsakis, Aristidis, additional, Tsegay, Guesh Mebrahtom, additional, Tsermpini, Evangelia Eirini, additional, Tumurkhuu, Munkhtuya, additional, Tung, Kang, additional, Ubah, Chukwudi S., additional, Udoakang, Aniefiok John, additional, Udoh, Arit, additional, Ullah, Atta, additional, Ullah, Sana, additional, Umair, Muhammad, additional, Umar, Tungki Pratama, additional, Unim, Brigid, additional, Unnikrishnan, Bhaskaran, additional, Upadhyay, Era, additional, Usman, Jibrin Sammani, additional, Vahabi, Seyed Mohammad, additional, Vaithinathan, Asokan Govindaraj, additional, Valizadeh, Rohollah, additional, Van den Eynde, Jef, additional, Varga, Orsolya, additional, Varma, Siddhartha Alluri, additional, Vart, Priya, additional, Varthya, Shoban Babu, additional, Vasankari, Tommi Juhani, additional, Vellingiri, Balachandar, additional, Vervoort, Dominique, additional, Villafañe, Jorge Hugo, additional, Violante, Francesco S., additional, Viskadourou, Maria, additional, Volovat, Simona Ruxandra, additional, Vos, Theo, additional, Vujcic, Isidora S., additional, Wafa, Hatem A., additional, Wahab, Feras, additional, Wang, Cong, additional, Wang, Fang, additional, Wang, Nelson, additional, Wang, Shu, additional, Wang, Yanzhong, additional, Wang, Yuan-Pang, additional, Wei, Melissa Y., additional, Werdecker, Andrea, additional, Wickramasinghe, Nuwan Darshana, additional, Wijeratne, Tissa, additional, Wilandika, Angga, additional, Wilson, Shadrach, additional, Wolfe, Charles D.A., additional, Wongsin, Utoomporn, additional, Wu, Zenghong, additional, Xiao, Hong, additional, Xu, Suowen, additional, Xu, Xiaoyue, additional, Yadav, Lalit, additional, Yano, Yuichiro, additional, Yaribeygi, Habib, additional, Yasufuku, Yuichi, additional, Nia, Iman Yazdani, additional, Ye, Pengpeng, additional, Yesuf, Subah Abderehim, additional, Yezli, Saber, additional, Yiğit, Arzu, additional, Yiğit, Vahit, additional, Yilma, Mekdes Tigistu, additional, Yon, Dong Keon, additional, Yonemoto, Naohiro, additional, Yousefi, Zabihollah, additional, Yperzeele, Laetitia, additional, Yu, Chuanhua, additional, Yunusa, Ismaeel, additional, Zafari, Nima, additional, Tajrishi, Farbod Zahedi, additional, Zakham, Fathiah, additional, Zastrozhin, Mikhail Sergeevich, additional, Zeineddine, Mohammad A., additional, Zemedikun, Dawit T., additional, Zeng, Youjie, additional, Zhai, Chunxia, additional, Zhang, Chen, additional, Zhang, Haijun, additional, Zhang, Hongwei, additional, Zhang, Liqun, additional, Zhang, Ning, additional, Zhang, Yunquan, additional, Zhao, Hanqing, additional, Zheng, Peng, additional, Zhong, Chenwen, additional, Zhou, Shuduo, additional, Zhu, Bin, additional, Zhu, Lei, additional, Zielińska, Magdalena, additional, Zikarg, Yossef Teshome, additional, Zmaili, Mohammad, additional, Zoeckler, Leo Zucker, additional, Zou, Zhiyong, additional, Zumla, Alimuddin, additional, Zweck, Elric, additional, and Zyoud, Samer H., additional

Published
2023
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12. Quality of Life Among Breast Cancer Patients Attending Hawassa University Comprehensive Specialized Hospital Cancer Treatment Center

Author

Kurabachew Mengistu, Dubale Dulla Koboto, Girma Ababi, Dereje Geleta, Lalisa Gemechu, Achamyelesh Gebretsadik, Netsanet Bogale, and Bedilu Deribe

Subjects
medicine.medical_specialty, Descriptive statistics, Medical treatment, business.industry, medicine.disease, Cancer treatment, Breast cancer, Oncology, Quality of life, Family medicine, Global health, Social domain, Medicine, Sampling (medicine), business
Abstract

Background Breast cancer affects the overall quality of life (QOL) among its survivors. Limited evidence is available about the QOL among cases. Therefore, this study was intended to assess the quality of life of breast cancer patients attending the cancer treatment center at Hawassa University Comprehensive Specialized Hospital, Hawassa, southern Ethiopia. Methods An institution-based cross-sectional study was conducted among breast cancer patients attending cancer treatment at the Hawassa University Comprehensive Specialized Hospital between April and June, 2019. All breast cancer patients attending treatment the center were included in the study by universal sampling. Data were collected using a structured questionnaire containing demographic data, patient clinical factors and Quality of Life Instrument (WHOQOL)-BREF version 3.0. The collected data were entered into EpiData software version 3.1 and analyzed using SPSS Version 20.0. Descriptive statistics were presented in tables. Results A total of 259 respondents with a mean age of (SD) 44.89 (12.56) participated in study. The mean score of overall global health scale was 75.3 (SD±17.1) with the mean health satisfaction was 12.43 (SD±3.98). The highest mean score was observed in environmental domain, 93.31 (SD±19.76), despite social domain being very low, 36.69 (SD±7.62). Most of the participants were highly satisfied with the health care service that was provided, with a mean score of 16.1 (SD±3.1). In contrast, the majority of study participants were disappointed with the need for any medical treatment, body appearance, luxurious activities, and sexual life, with mean scores of 8.93 (SD±3.68), 8.74 (SD±4.26), 9.1 (SD±4.22), and 8.1 (SD±4.14), respectively. Conclusion Breast cancer patients in southern Ethiopia suffered from poor social and psychological support that, in turn, highly affected their life value. Therefore, due attention should be given to enhance social and psychological support for breast cancer patients as a whole.

Published
2020
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13. Prevalence of depression and anxiety symptoms and their determinant factors among patients with cancer in southern Ethiopia: a cross-sectional study

Author

Mohammed Ayalew, Bedilu Deribe, Bereket Duko, Dereje Geleta, Netsanet Bogale, Lalisa Gemechu, Achamyelesh Gebretsadik, Asres Bedaso, Ayalew, Mohammed, Deribe, Bedilu, Duko, Bereket, Geleta, Dereje, Bogale, Netsanet, Gemechu, Lalisa, Gebretsadik, Achamyelesh, and Bedaso, Asres

Subjects
suicide & self-harm, Depression, General Medicine, Anxiety, 1103 Clinical Sciences, 1117 Public Health and Health Services, 1199 Other Medical and Health Sciences, Cross-Sectional Studies, Mental Health, anxiety disorders, Neoplasms, depression & mood disorders, oncology, Prevalence, Medicine, Humans, Ethiopia, adult psychiatry
Abstract

ObjectiveThe study was aimed to assess the prevalence of depression and anxiety symptoms and their determinant factors among patients with cancer attending follow-up at Hawassa University Comprehensive Specialized Hospital cancer treatment centre, Ethiopia.DesignInstitution-based cross-sectional study design was implemented.SettingPatients with cancer at Hawassa University Comprehensive Specialized Hospital cancer treatment centre from October 2019 to December 2019.ParticipantsRandomly selected 415 patients with cancer who had follow-up at cancer treatment centre.Main outcome measuresAnxiety and depression symptoms were assessed using Hospital Anxiety and Depression Scale.ResultThe prevalence rates of depression and anxiety symptoms were found to be 244 (58.8%) and 249 (60.0%), respectively. Older age (>50 years) (AOR (adjusted OR)=2.24, 95% CI=1.14 to 4.40), being unemployed (AOR=1.96, 95% CI=1.08 to 3.56), advanced stage of cancer such as stage III (AOR=5.37, 95% CI=1.34 to 21.45) and stage IV (AOR=4.55, 95% CI=1.12 to 18.44), comorbid psychotic symptoms (AOR=1.67, 95% CI=1.07 to 2.61) and eating problem in the past 2 weeks (AOR=6.16, 95% CI=1.98 to 19.11) were independent factors significantly associated with depressive symptoms. In addition, cancer stage such as stage II (AOR=3.92, 95% CI=1.07 to 14.36) and stage IV (AOR=5.04, 95% CI=1.44 to 17.59) and comorbid psychotic symptoms (AOR=1.73, 95% CI=1.12 to 2.66) were significantly associated with anxiety symptoms.ConclusionDepression and anxiety symptoms among patients with cancer were considerably high. Age, occupation, cancer stage, comorbid psychotic symptoms and eating problem were determinant factors of depressive symptoms among patients with cancer. Moreover, cancer stage and comorbid psychosis were determinants of anxiety symptoms. Healthcare professionals working in the oncology unity need to conduct routine screening and treatment of depression and anxiety symptoms for patients with cancer.

Published
2022

14. Short-Course 2-Dimensional Radiation Therapy in the Palliative Treatment of Esophageal Cancer in a Developing Country: A Phase II Study (Sharon Project)

Author

E. Farina, Milly Buwenge, Alessio G. Morganti, Biniyam Tefera Deressa, Netsanet Bogale, Wondemagegnehu Tigeneh, Deressa B.T., Tigeneh W., Bogale N., Buwenge M., Morganti A.G., and Farina E.

Subjects
Adult, Male, Cancer Research, medicine.medical_specialty, Esophageal Neoplasms, medicine.medical_treatment, Adenocarcinoma, 030218 nuclear medicine & medical imaging, 03 medical and health sciences, 0302 clinical medicine, Laryngopharyngeal Reflux, medicine, Back pain, Humans, Radiology, Nuclear Medicine and imaging, Prospective Studies, Karnofsky Performance Status, Esophagus, Developing Countries, Aged, Radiation, Performance status, business.industry, Palliative Care, Middle Aged, Esophageal cancer, medicine.disease, Dysphagia, short course radiotherapy, palliative treatment, Esophageal Cancer, developing countries, Surgery, Radiation therapy, medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, Carcinoma, Squamous Cell, Quality of Life, Female, Radiation Dose Hypofractionation, Esophagogastric Junction, Ethiopia, medicine.symptom, Accelerated Radiation Therapy, Deglutition Disorders, business, Odynophagia
Abstract

Purpose Patients with locally advanced and metastatic esophageal cancer are usually affected by cancer-related symptoms, which worsen their performance status and quality of life. The aim of this study was to determine the efficacy of short-course accelerated radiation therapy for symptomatic palliation in a low resourced setting where only a 2-dimensional radiation therapy (RT) technique was available. Methods and Materials A phase II trial based on Simon’s 2-stage design was planned. A total dose of 12 Gy in 4 fractions, twice per day, over 2 days, ≥8 hours apart, using a 2-dimensional conventional RT technique was delivered with a Cobalt 60 unit (Equinox, Best Theratronics, Ottawa, Ontario). Symptoms were graded using the International Atomic Energy Agency scoring system. Results A total of 17 patients were treated (male/female = 10/7; median age, 50.0 years; range, 27-78 years; histology: 6 adenocarcinomas and 11 squamous cell carcinomas; tumor site: 4 gastresophageal junction and 13 esophagus). The most frequent baseline symptoms were dysphagia or regurgitation (100%), odynophagia (76%), and chest or back pain (53%). At 1 month after RT, all patients were alive with palliative response rates (complete plus partial) for dysphagia, regurgitation, odynophagia, and chest or back pain of 76%, 82%, 69%, and 56%, respectively. No patients presented acute ≥G3 toxicity. Conclusions Short-course accelerated radiation therapy treatment, planned and delivered using a conventional 2-dimensional RT technique, was effective and well tolerated for the symptomatic palliation of locally advanced or metastatic esophageal cancer. This schedule may be useful for RT centers in developing countries to reduce treatment times, costs, and patient waiting times before treatment.

Published
2020
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15. Perceived Quality of Nursing Care Among Cancer Patients Attending Hawassa University Comprehensive Specialized Hospital Cancer Treatment Center; Hawassa Southern Ethiopia: Cross-Sectional Study

Author

Lalisa Gemechu, Kurabachew Mengistu, Achamyelesh Gebretsadik, Netsanet Bogale, Mohammed Biset Ayalew, Anteneh Gadissa, Bedilu Deribe, Dubale Dula, Girma Ababi, and Dereje Geleta

Subjects
0301 basic medicine, medicine.medical_specialty, Cross-sectional study, Hawassa, 03 medical and health sciences, Nursing care, 0302 clinical medicine, Breast cancer, medicine, cancer, Original Research, Descriptive statistics, business.industry, quality of nursing care, Medical record, patents with cancer, Cancer, medicine.disease, Oncology nursing, 030104 developmental biology, Oncology, Cancer Management and Research, 030220 oncology & carcinogenesis, Family medicine, Spiritual care, business
Abstract

Bedilu Deribe,1 Mohammed Ayalew,1 Dereje Geleta,2 Lalisa Gemechu,3 Netsanet Bogale,4 Kurabachew Mengistu,4 Anteneh Gadissa,4 Dubale Dula,5 Girma Ababi,6 Achamyelesh Gebretsadik2 1Hawassa University School of Nursing, Hawassa, Ethiopia; 2Hawassa University School of Public Health, Hawassa, Ethiopia; 3Hawassa University Department of Environmental Health, Hawassa, Ethiopia; 4Hawassa University Faculty of Medicine, Hawassa, Ethiopia; 5Hawassa University Department of Midwifery, Hawassa, Ethiopia; 6Yanet Medical Center, Hawassa, EthiopiaCorrespondence: Bedilu DeribeHawassa University School of Nursing, Hawassa, South Ethiopia, EthiopiaTel +251933220151Email bediluderibe2002@gmail.comBackground: Cancer has become one of the most common and the second leading cause of death. According to grounded theory, quality care is meeting all the needs of the patients. Low-quality nursing care relates omission of nursing care required to meet patients’ need. Quality of nursing care in oncologic setting was nursing practice area where studies are limited.Objective: The aim of the study was to assess the perceived quality of nursing care among patients with cancer attending Hawassa University comprehensive specialized Hospital.Methods: A quantitative Cross-sectional study was conducted. Among the proposed 422 patients with cancer, using a simple random sampling technique 415 patients were included in this study. Seven data were discarded due to incompleteness and inconsistency between collected data and patient medical record. Data were collected using structured questionnaires and Quality of Oncology Nursing Care Scale. We carried out statistical analysis using SPSS V-20. We used descriptive analysis to examine the quality of oncology nursing care.Results: The mean age of patients was 42.51 (± 14.24) years, among patients diagnosed with cancer more than one-third 148 (35.70%) had breast cancer. The majority of patients with cancer 173 (41.70%) were in stage-III. Nearly two-third 266 (64.10%) of patients were on chemotherapy. Among study participants on treatment, 249 (60.00%) perceived they received good quality of nursing care. The mean score related to the domain of support and confirmation is 62.73 ± 7.26. In terms of spiritual care, the mean score is 21.03 ± 5.37.Conclusion: The perceived quality of nursing care was high however not all domains of oncology care were achieved. We recommend Detail and focused study to explore important predictors’ quality nursing care.Keywords: cancer, Hawassa, patents with cancer, quality of nursing care

Published
2021

16. Supplemental Material, Sampling_frame - Prevalence and Predictor of Cervical Cancer Screening Service Uptake Among Women Aged 25 Years and Above in Sidama Zone, Southern Ethiopia, Using Health Belief Model

Author

Ermias Yunkura Gemeda, Belayneh Bekele Kare, Dereje Geleta Negera, Lalisa Gemechu Bona, Bedilu Deribe Derese, Netsanet Bogale Akale, Kurabachew Mengistu Kebede, Dubale Dulla Koboto, and Achamyelesh Gebretsadik Tekle

Subjects
FOS: Clinical medicine, 111299 Oncology and Carcinogenesis not elsewhere classified
Abstract

Supplemental Material, Sampling_frame for Prevalence and Predictor of Cervical Cancer Screening Service Uptake Among Women Aged 25 Years and Above in Sidama Zone, Southern Ethiopia, Using Health Belief Model by Ermias Yunkura Gemeda, Belayneh Bekele Kare, Dereje Geleta Negera, Lalisa Gemechu Bona, Bedilu Deribe Derese, Netsanet Bogale Akale, Kurabachew Mengistu Kebede, Dubale Dulla Koboto and Achamyelesh Gebretsadik Tekle in Cancer Control

Published
2020
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17. Prevalence and Predictor of Cervical Cancer Screening Service Uptake Among Women Aged 25 Years and Above in Sidama Zone, Southern Ethiopia, Using Health Belief Model

Author

Gemeda, Ermias Yunkura, primary, Kare, Belayneh Bekele, additional, Negera, Dereje Geleta, additional, Bona, Lalisa Gemechu, additional, Derese, Bedilu Deribe, additional, Akale, Netsanet Bogale, additional, Kebede, Kurabachew Mengistu, additional, Koboto, Dubale Dulla, additional, and Tekle, Achamyelesh Gebretsadik, additional

Published
2020
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18. Hernia repair prevalence by age and gender among the Australian adult population from 2017 to 2021

Author

Thi Nga Le, Mohammad Afshar Ali, Svetla Gadzhanova, Renly Lim, Indu Bala, Kumsa Netsanet Bogale, and Marianne Gillam

Subjects
Hernia repair, Australia, prevalence, Public aspects of medicine, RA1-1270, Medicine (General), R5-920
Abstract

Despite of high annual rate of surgery worldwide, few national-level studies have explored the epidemiological aspects of various types of hernia repairs. Our study aims to examine the 5-year prevalence of hernia repairs in Australian adults. The number of hernia repair surgeries for femoral, inguinal, incisional, other abdominal, and epigastric hernias were extracted from the Australian Institute of Health and Welfare (AIHW) database from financial year (FY) FY2017 to FY2021. We calculated age-specific prevalence and prevalence ratio (PR) with a 95% confidence interval (CI) to compare the prevalence of hernia repairs by age group and sex. The highest prevalence per 100,000 population of hernia repairs was found in inguinal (223), followed by epigastric (111), other abdominal (59), incisional (52), and femoral hernia (10). People over 65 years old had highest PR of hernias. There was a gender-wise variation across types of hernia procedures. Around 89.6% of patients with inguinal hernia repairs were males, while only 10.4% were females. The PR was lower in males for femoral and incisional hernia when compared two genders with corresponding age groups. Women in the pregnancy group (20–39 years) had a high risk of ventral hernia repair when compared to males. Groups of patients who have higher risks of hernia repair should be prioritized for healthcare service delivery, but more research is needed in hernia epidemiology, in Australia and internationally. Also, our study could serve as a national and international reference for other hernia repair studies where healthcare system is comparable.

Published
2024
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